GenomeNet

Database: Pfam
Entry: HTH_15
LinkDB: HTH_15
Original site: HTH_15 
#=GF ID   HTH_15
#=GF AC   PF12324.9
#=GF DE   Helix-turn-helix domain of alkylmercury lyase
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Gavin OL;
#=GF SE   Pfam-B_3505 (release 6.5)
#=GF GA   26.00 26.00;
#=GF TC   26.00 26.30;
#=GF NC   25.90 25.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Helix-turn-helix
#=GF DR   INTERPRO; IPR024259;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Alkylmercury lyase (EC:4.99.1.2) cleaves the carbon-mercury bond
#=GF CC   of organomercurials such as phenylmercuric acetate. This is the
#=GF CC   N terminal helix-turn-helix domain associated with Pfam:PF03243.
#=GF SQ   104
#=GS A0A238XE03_9PSEU/5-78     AC A0A238XE03.1
#=GS A0A0H5CCT3_9PSEU/2-64     AC A0A0H5CCT3.1
#=GS A0A1I1V331_9GAMM/6-78     AC A0A1I1V331.1
#=GS A0A077HKA5_9CORY/4-75     AC A0A077HKA5.1
#=GS F4CKR9_PSEUX/7-80         AC F4CKR9.1
#=GS G8MQ32_9BURK/2-74         AC G8MQ32.1
#=GS A0A1X1RHQ1_MYCCE/12-71    AC A0A1X1RHQ1.1
#=GS A0A292YZ31_9PSEU/8-81     AC A0A292YZ31.1
#=GS A0A1G9MES5_9ACTN/3-76     AC A0A1G9MES5.1
#=GS A0A0S3F5S7_9SPHN/3-74     AC A0A0S3F5S7.1
#=GS L7KT22_9ACTN/4-74         AC L7KT22.1
#=GS A0A1L3MDB1_9MICO/6-76     AC A0A1L3MDB1.1
#=GS A0A0M2K6C8_9MYCO/7-78     AC A0A0M2K6C8.1
#=GS A0A443HHB9_BYSSP/12-80    AC A0A443HHB9.1
#=GS I7IXG7_9CORY/4-75         AC I7IXG7.1
#=GS A0A0M8NNU5_9EURO/12-80    AC A0A0M8NNU5.1
#=GS K9AZL2_9MICO/3-76         AC K9AZL2.1
#=GS A0A2S2F980_9GAMM/6-77     AC A0A2S2F980.1
#=GS W9HAK1_9HYPO/2-72         AC W9HAK1.1
#=GS A0A0D1LE86_9MYCO/2-72     AC A0A0D1LE86.1
#=GS A0A1I1C415_9PSEU/9-80     AC A0A1I1C415.1
#=GS A0A2V4AXI6_9PSEU/5-77     AC A0A2V4AXI6.1
#=GS A0A1E7KGR4_9ACTN/7-80     AC A0A1E7KGR4.1
#=GS G8MQ18_9BURK/8-79         AC G8MQ18.1
#=GS F3NQD4_9ACTN/7-80         AC F3NQD4.1
#=GS A0A345XRV8_9ACTN/7-78     AC A0A345XRV8.1
#=GS A0A172UGQ6_9MYCO/6-76     AC A0A172UGQ6.1
#=GS C8PXI0_9PROT/5-78         AC C8PXI0.1
#=GS A0A1X0K9H8_9MYCO/11-84    AC A0A1X0K9H8.1
#=GS A0A069DL31_9BACL/7-78     AC A0A069DL31.1
#=GS A0A2S5TPC1_9RHIZ/2-75     AC A0A2S5TPC1.1
#=GS A0A2N0ZAM6_9BACI/7-80     AC A0A2N0ZAM6.1
#=GS A0A1H2L7Z9_9ACTN/25-77    AC A0A1H2L7Z9.1
#=GS D3PUY2_STANL/7-80         AC D3PUY2.1
#=GS A0A3A5N257_9MICC/2-75     AC A0A3A5N257.1
#=GS A0A2G1UGG2_9ALTE/7-75     AC A0A2G1UGG2.1
#=GS A0A3M8B3N1_9BACL/7-79     AC A0A3M8B3N1.1
#=GS A0A212U6I1_9MICO/3-72     AC A0A212U6I1.1
#=GS Q0AM71_MARMM/6-80         AC Q0AM71.1
#=GS L7KT71_9ACTN/5-74         AC L7KT71.1
#=GS A0A072TFB1_MEDTR/753-825  AC A0A072TFB1.1
#=GS B2I418_MYCMM/7-79         AC B2I418.1
#=GS A0A0F0LWT7_9MICO/6-75     AC A0A0F0LWT7.1
#=GS A0A2N7VRF1_9BURK/19-52    AC A0A2N7VRF1.1
#=GS A0A2A2TFF1_9CYAN/8-67     AC A0A2A2TFF1.1
#=GS A0A263CX74_9PSEU/7-78     AC A0A263CX74.1
#=GS U2TEH2_LEIAQ/4-73         AC U2TEH2.1
#=GS A4V7U8_PSEFS/6-77         AC A4V7U8.1
#=GS A0A1I1CL81_9PSEU/7-78     AC A0A1I1CL81.1
#=GS A0A0M8VCX8_9ACTN/7-80     AC A0A0M8VCX8.1
#=GS A0A1N7SP71_9BURK/6-79     AC A0A1N7SP71.1
#=GS A0A176I7H1_9GAMM/6-75     AC A0A176I7H1.1
#=GS W9GD57_9MICO/1-70         AC W9GD57.1
#=GS A0A1R1LCR2_9MICC/3-75     AC A0A1R1LCR2.1
#=GS A0A0Q7U5N2_9MICO/2-72     AC A0A0Q7U5N2.1
#=GS A0A1E8Q813_9MYCO/7-78     AC A0A1E8Q813.1
#=GS A0A2V4B1U6_9PSEU/1-34     AC A0A2V4B1U6.1
#=GS E2SED0_9ACTN/3-75         AC E2SED0.1
#=GS A0A1G9BC44_9MICO/5-75     AC A0A1G9BC44.1
#=GS A0A100W685_9MYCO/104-170  AC A0A100W685.1
#=GS A0A1X1YVR8_9MYCO/8-74     AC A0A1X1YVR8.1
#=GS A0A3D9UZ11_9MICO/3-76     AC A0A3D9UZ11.1
#=GS A0A0W1SI08_9GAMM/7-75     AC A0A0W1SI08.1
#=GS U1LQT7_9MICO/6-76         AC U1LQT7.1
#=GS A0A176I8U8_9GAMM/7-75     AC A0A176I8U8.1
#=GS V8CUJ7_9ACTN/5-76         AC V8CUJ7.1
#=GS A0A0J1D4T7_9BURK/5-78     AC A0A0J1D4T7.1
#=GS A0A2S2C7G9_9NOCA/4-74     AC A0A2S2C7G9.1
#=GS A0A132PAZ3_9MYCO/6-76     AC A0A132PAZ3.1
#=GS A0A3N3ZT65_9MICC/3-72     AC A0A3N3ZT65.1
#=GS G2G622_9ACTN/6-78         AC G2G622.1
#=GS A0A2V5EYY4_9MICC/2-75     AC A0A2V5EYY4.1
#=GS A0A346XV98_9ACTN/194-265  AC A0A346XV98.1
#=GS A0A3N4A9Y9_9PSED/7-73     AC A0A3N4A9Y9.1
#=GS U4L7Y8_PYROM/62-133       AC U4L7Y8.1
#=GS A0A1R4FMP8_9MICC/3-76     AC A0A1R4FMP8.1
#=GS A0A223S7P3_9ACTN/6-78     AC A0A223S7P3.1
#=GS A0A2T0M098_9PSEU/18-90    AC A0A2T0M098.1
#=GS A0A1V6PPQ7_9EURO/15-80    AC A0A1V6PPQ7.1
#=GS A0A2S2F8Z4_9GAMM/6-78     AC A0A2S2F8Z4.1
#=GS A4A3F8_9GAMM/7-75         AC A4A3F8.1
#=GS A0A0Q2UJA4_MYCGO/3-76     AC A0A0Q2UJA4.1
#=GS A0A0J6W8G5_9MYCO/2-72     AC A0A0J6W8G5.1
#=GS A0A1G5D7R2_9GAMM/16-76    AC A0A1G5D7R2.1
#=GS A0A316TP18_9ACTN/1-68     AC A0A316TP18.1
#=GS I4BSM2_MYCCN/7-78         AC I4BSM2.1
#=GS A0A2D0A3E5_9BURK/6-79     AC A0A2D0A3E5.1
#=GS A0A326UC72_9CHLR/9-76     AC A0A326UC72.1
#=GS A0A2V5F9X2_9MICC/6-78     AC A0A2V5F9X2.1
#=GS G2I8Q9_KOMMN/8-79         AC G2I8Q9.1
#=GS A0A0F7N5V0_9ACTN/7-78     AC A0A0F7N5V0.1
#=GS A0A1M5B4Y5_9GAMM/9-75     AC A0A1M5B4Y5.1
#=GS A0A2N7VRE8_9BURK/6-79     AC A0A2N7VRE8.1
#=GS A0A097IGF9_9CORY/4-75     AC A0A097IGF9.1
#=GS G2GNS4_9ACTN/6-78         AC G2GNS4.1
#=GS D4YL19_9MICO/3-76         AC D4YL19.1
#=GS B5EAP1_GEOBB/5-72         AC B5EAP1.1
#=GS A0A411YIA5_9ACTN/52-124   AC A0A411YIA5.1
#=GS C7NGB6_KYTSD/14-83        AC C7NGB6.1
#=GS A0A328VBB2_9CHLR/9-82     AC A0A328VBB2.1
#=GS A0A401ZEL1_9CHLR/8-79     AC A0A401ZEL1.1
#=GS L7LNN2_9ACTN/6-76         AC L7LNN2.1
#=GS D0L7Y2_GORB4/5-74         AC D0L7Y2.1
#=GS A0A260WP56_9NOCA/3-76     AC A0A260WP56.1
A0A238XE03_9PSEU/5-78                ...................ylad----RLSETLSPNLADPDLSWLWPPLLRLLACGSPVTVARLAAATGRTEPDVRRALARL..S..DTEYDEHGRIVGWG..
A0A0H5CCT3_9PSEU/2-64                ...................pals----------------AAEVRIAVALWRLLAEGEPVPVGALADRLGDAAGDVTAAVDGVlaG..SCQRDERGDIVA--f.
A0A1I1V331_9GAMM/6-78                ...........thlterllpifp-------------DFGAEGRELVRPLFRRLAHGRPVEPAELAAASGWSTAAVNETLSRW..W..GIRYDEEGRINGF-w.
A0A077HKA5_9CORY/4-75                .................tdqalt--------YLLSPARSGIDPELFVPLLRLLAEGEPVTVAELATASGRSEDTVRQGLAAV..P..DTEYDDEGRIIGL-a.
F4CKR9_PSEUX/7-80                    .......................QLVAQLADALYGTGHPATQPWLFRPLLRLLAEGEPVTLDRLAEAAGTSVDQVRQALAAE..P..DTEYDADGRVVGLG..
G8MQ32_9BURK/2-74                    .................klapyi------LERLTPTNRPKGFAEFLVALLGELAKGRPISRTTLARTLGWPAEQVAAVLEQA..T..STEYDNDGNIIG--y.
A0A1X1RHQ1_MYCCE/12-71               ..................irhdv-------------------ARFMVPMIRLVAEGRPVALERLAAASGVPVEEIESWLRAQ..P..GTDWDEDGRLLGFG..
A0A292YZ31_9PSEU/8-81                ......................h-LATRLGETVRSTTGADVMGQLWPVLLRELAAGHPVTVEGLGRVSGRGVVEVRDGLGGL..S..DTEYDETGAVLGH-r.
A0A1G9MES5_9ACTN/3-76                .......................DLSTQLPDRLNRPEETGLDPGLLVPLLRLLVDGDPVTIEQLATAAGRTPEQVCNGLAAV..P..DTEYDDQGRIVGQG..
A0A0S3F5S7_9SPHN/3-74                ......................p---TTYIEHFPSISRSQDSAELLVALLRELAKGRPVSRTTLAGILNWPDERIAAVLAQT..A..STEYDDDGNIIGHG..
L7KT22_9ACTN/4-74                    ..................dnlta-------DVFAKILPAGRDRALMRAALRLLAHGTPVTVTELAAAAGVPDLDPAQT-PIG..A..DVEYDEAGRIVGWG..
A0A1L3MDB1_9MICO/6-76                ...................phev------TERL-ASAETGMQPWLWVPALRLLAQGDPVDVQDLAGAVGRPVEEVRAAMETV..P..DVEYDGEGRIIGWG..
A0A0M2K6C8_9MYCO/7-78                ...........tvvstmdsvfsr------------QDSP--AGWLWQPLLRQLARGEPLTIADLAAATGRAGDEVAQAVGRL..R..DTEYDDAGRIVGYG..
A0A443HHB9_BYSSP/12-80               ........eqlknqlladmmaip--------------------AFFPALLRLVSRGEPVPIAALATEVHIPIHDIEQWLRQQ..P..GTDWDSQGRLLGFG..
I7IXG7_9CORY/4-75                    .................tdqalt--------YLLSPARSGIDPELFVPLLRLLAEGEPVTVAELATASGRSEDTVRQGLAAV..P..DTEYDDEGRIIGL-a.
A0A0M8NNU5_9EURO/12-80               ........eqlknqlladmmaip--------------------AFFPALLRLVSRGEPVPIAALATEVHIPIHDIEQWLRQQ..P..GTDWDSQGRLLGFG..
K9AZL2_9MICO/3-76                    .......................DLSTQLPDRLNRPEETGLDPGLLVPLLRLLVDGDPVTIEQLATAAGRTPEQACNGLAAV..P..DTEYDDQGRIVGQG..
A0A2S2F980_9GAMM/6-77                ......fvkeiaerfsvinrlhp-------------------TELLLPLLREIAKGSPVSRKTLATVLDWPADRVAAALDQV..P..STEYDDDGNIVGYG..
W9HAK1_9HYPO/2-72                    ..........aqllvdmvtflkd----------------QDLTTFLCTLLQLVAKGEPVPLTFLAAEAGLPLEQVESLLRAQ..R..GTDWDEQGRLLGFG..
A0A0D1LE86_9MYCO/2-72                .....................pn-----FLDRLTIPEESGLDPTMLVPLLRLLAAGEPVTVEALAAAVGLPVDEVTRRLAAV..P..DTEYDEQGRIVGQG..
A0A1I1C415_9PSEU/9-80                ....................gga-----LGDALKSTLNDSTLPWLWRPLLQLLARGEPVTVDDLAQATGRDADEVRRTVAAL..P..DTEYDEQGRILGYG..
A0A2V4AXI6_9PSEU/5-77                ......................h-FATDLADKLFGTDAATTGTSLMRAALRLLAHGEPITVTQLATAADVSAAAVESAPAA-..Q..DIEYDDQRRIVGWG..
A0A1E7KGR4_9ACTN/7-80                .......................QLTDRLTTAFAAAGHATARPWLWPALLKLLGRGEAVTTTQLADTTGKSEDEVRHALATL..P..DTEYDAAGRIVGSG..
G8MQ18_9BURK/8-79                    ......................p---TTYIEHFPSISRSQDSAELLVALLRELAKGRPVSRTTLAGILNWPDERIAAVLAQT..A..STEYDDDGNIIGHG..
F3NQD4_9ACTN/7-80                    ......................k-LADRLTAALGGGENVTGQPWLWRPLLQLLATGRPVTTGQLATATSHTEDDVRHALAAM..P..DTEYDGTGRIIGSG..
A0A345XRV8_9ACTN/7-78                .......................ELATRFSDTV--NRAPGVKLWLLRPLLRLLATGEPVTLDQLAAQADRTTEEIRAALADM..P..DTEYDTAGHIIGDG..
A0A172UGQ6_9MYCO/6-76                .................fattiv-------DTLFDS-TANTGTNLMGTAMRLLAAGEPITIEQLATAAGASVADVENAPA-A..A..DIEYDDRHRILGWG..
C8PXI0_9PROT/5-78                    .....................ry--VTEIANRLIPANQPKNLASLFSVLLHELIKGQSVSPTILATALNCDLEQLASILKEI..P..GIEYDNTGDIVGYG..
A0A1X0K9H8_9MYCO/11-84               .........aanlceklfgapnt-------------VGAGTRSHLLRVALRLLANGEPISPAHLAATAGVCKTELENA-TAS..T..DIEYDDQGRIVGWG..
A0A069DL31_9BACL/7-78                .......................ELVTLFDQN--KGEGGGSMKWLFRPLLQMLTKGEPVTVEDIATTTGKPLDEVKDILSTL..S..SVELDEQGRVVGFG..
A0A2S5TPC1_9RHIZ/2-75                .................klapyi------LERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQA..T..STEYDKDGNIIGYG..
A0A2N0ZAM6_9BACI/7-80                .......................ELVTLLDQRSKKREGGSSMQWIFRPTLQMLTEGEPVTIEDIATATGKPVEEVGKVVQSL..P..SVELDEQGRVVGYG..
A0A1H2L7Z9_9ACTN/25-77               .................plhigr---------------------------QLLTAGEPVTVDQVATAGGWTIEQLSTELRKH..P..GVDWTDDGRIAGFG..
D3PUY2_STANL/7-80                    ......................r-FDTWLSTSLADSEVGGGAWTIARSIQKLLLDGKPVPVAGLAAETGRSVEEVEQALEAM..P..SVEREPDGTVVGFG..
A0A3A5N257_9MICC/2-75                .................klapyi------LERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQA..T..STEYDKDGNIIGYG..
A0A2G1UGG2_9ALTE/7-75                ...............iverlglt---------------GEREAALHVTLLRELALGQPVTVERLAKSLNWTTDEAELVLEKL..PcgTIEYDGQGRLIGSG..
A0A3M8B3N1_9BACL/7-79                .......................QLANQLNKQF-DQGEASSMKWLFQPLLELLAKGEPVSVEDIVETTGKSVEEVENILSEL..P..SVERDEQGRVVGYG..
A0A212U6I1_9MICO/3-72                ......................d-LSMQLPERLSRLGE----TGLLIPLLRLLADGDPVTVQQLSVAAGRTIDEVRLGLAAM..Q..DTEYDDQGRIVGQG..
Q0AM71_MARMM/6-80                    .........qitavleagyigen---------------PKDLQRASLYIYRALASGKPISIASIAEHLGTPLETASRLLNLV..PpsAIELDDDGHIIGF-v.
L7KT71_9ACTN/5-74                    ................sipadvf----------ATIAPADRDRALLRAALRLLAHGAPVTVTELAAAAGVDAGDLEET-PIG..A..DIEYDEQGRVLGWG..
A0A072TFB1_MEDTR/753-825             ....................hta----ELVERLAMANQLEGFADLFVVLLRELSKGAPVSPAALALALDWPIERVSVALEQA..V..STEWDDYGNVVGYG..
B2I418_MYCMM/7-79                    .......................QLAHRLNDSL-GGDNPGSTPWMLRPLLDLLAHGAPVTIDQLADATATTVEQVRHALTAM..S..DTEYDEHGRIIGSG..
A0A0F0LWT7_9MICO/6-75                ...................aait-------DRL-ATAETGLEIWLWLPLLKLLAEGEPVTIADLATATGRTADEVQAALAAV..P..DTEYDDEGQIIGQG..
A0A2N7VRF1_9BURK/19-52               ..................lpprs---------------------------------------------RWPVERVAVALKQS..V..STEWDDDGNVTGYG..
A0A2A2TFF1_9CYAN/8-67                ...................kqtr----VYQQAFAEGEQEGIEEGKLFAVPPMLAAG--LTVEQIAEALGLTVDEVRQAAQAQ..S..S-------------q.
A0A263CX74_9PSEU/7-78                ...............tiastmdn--------VFSRQDSP--AGWLWQPLLRLLARGEPVTIADLAAATGRPGDEVAQAVGRL..R..DTEYDDAGRIVGYG..
U2TEH2_LEIAQ/4-73                    .....................nd----TLAERL-TSSETGQEASLWLPLMKLLAQGDPVEVSTLATVTGRSEADVQQALAAV..P..DIEYE-YGRIIGQG..
A4V7U8_PSEFS/6-77                    .....................yi---TEIAERLTPTNRPKGFAEFLVALLGELAKGRPISRTTLARTLGWPAEQVAAVLEQA..T..STEYDNDGNIIG--y.
A0A1I1CL81_9PSEU/7-78                .................tlastm------DSVFSRQDSP--TGWLWHPLLLLLSRGEPVTIPDLAITTGRAEEEVKQAMEQL..P..DTEYDDTGRIVGYG..
A0A0M8VCX8_9ACTN/7-80                ......................k-LADRLTAALGGGENVTGQPWLWRPLLQLLATGRPVTTGQLATATSHTEDDVRHALAAM..P..DTEYDETGRIIGSG..
A0A1N7SP71_9BURK/6-79                ....................hyt---TELVERLTTAVPTEGFTELFVALLRELAKGKPVAPATLAAALQWPPERVAAALEQA..V..STEWDEDGNVVGYG..
A0A176I7H1_9GAMM/6-75                ..............eiverlglt---------------GEREAALHVTLLRELALGQPVTVERLAKSLNWTTDEAELVLEKL..PcgTIEYDGQGRLIGSG..
W9GD57_9MICO/1-70                    ......................e-----LTARLARTDETGLDAGLLIPLLRLLVDGEPVSVEQLAAAAGRRAEEVRRALAAV..P..DTEYDDQDRIVGQG..
A0A1R1LCR2_9MICC/3-75                .....................dn--ATQITERL-ASSETGMQPWLWLPLMRLLAQGDPVDVDDLAATTGRPVDDVRSALAAM..A..DTEYDGSGRIIGQG..
A0A0Q7U5N2_9MICO/2-72                .....................td-LTTDLSDRLARF----DEEALLVPLLRLLVDGDPVTIDDLAGAVKLPVDEVRARLAAT..P..DTEYDGQGRIIGQG..
A0A1E8Q813_9MYCO/7-78                ...........tvvstmdsvfsr------------QDSP--AGWLWQPLLRQLARGEPLTIADLAAATGRAGDEVAQAVGRL..R..DTEYDDAGRIVGYG..
A0A2V4B1U6_9PSEU/1-34                .....................md------------------------------------------AAHGQPVEEIRRALVTS..P..DIEYDDQGRIVGAG..
E2SED0_9ACTN/3-75                    .......................DLSSQLPQRLTRPEETGLDAGLLIPLLRLLVDGDAVTVEELAAAAGRTLEEVRRGLAAV..P..DTEYD-QGRIIGQG..
A0A1G9BC44_9MICO/5-75                .....................tn----QVTERL-TSGDAGLETWLWLPLMKLLAKGDAVDIADLAAASGRPAEDVHRALAAV..P..DTEYDGSGRIIGQG..
A0A100W685_9MYCO/104-170             ..............adsvsrdtd---------------QKTGRHLMRTAVRLLAGGGPVTVADLCAAAGVDRADLTTA-PAG..R..DIEYDDHHRIIGWG..
A0A1X1YVR8_9MYCO/8-74                ..............aadtllgph---------------HQAGRKLMRAAVRLLADGEPITMSQLATAAGVEVGDLTTT-PAG..H..DIEYDDQHRIIGWG..
A0A3D9UZ11_9MICO/3-76                .......................DLSTQLSQRLTGTEETGLDAGLLIPLLRLLVDGDPVTVEQLAAVAGCTLDEVRRGLAAV..P..DTEYDEQGRIIGQG..
A0A0W1SI08_9GAMM/7-75                ...............iverlglt---------------GEREAALHVTLLRELALGQPVTVERLAKSLNWTTDEAELVLEKL..PcgTIEYDGQGRLIGSG..
U1LQT7_9MICO/6-76                    ....................arq-----VTERL-ATAESGMQPWLWMPMLRLLAQGNPVILEDLATAVGRPVQEVRGAVEAV..P..DIEYDGEGRIIGLG..
A0A176I8U8_9GAMM/7-75                ...............iverlglt---------------GEREAALHVTLLRELALGQPVTVERLAKSLNWTTDEAELVLEKL..PcgTIEYDGQGRLIGSG..
V8CUJ7_9ACTN/5-76                    .....................pf--ATTIVDTLFDSTANAGTNLMGIA-MRLLAAGEPITIEQLAAAVGADVADVENAPA-A..A..DIEYDDQHRILGWG..
A0A0J1D4T7_9BURK/5-78                ....................hyt---SELVERLTLANRSESFADLFVVLLRELTKGAPVSPAALALALNWPVERVTAALEQA..V..STEWDDDGNVLGYG..
A0A2S2C7G9_9NOCA/4-74                ..................dnlta-------DVFAKILPAGRDRALMRAALRLLAHGTPVTVTELAAAAGVPDLDPAQT-PIG..A..DVEYDEAGRIVGWG..
A0A132PAZ3_9MYCO/6-76                .................fattiv-------DTLFDS-TANTGTNLMGTAMRLLAAGEPITIEQLATAAGASVADVENAPA-A..A..DIEYDDRHRILGWG..
A0A3N3ZT65_9MICC/3-72                ......................d-LSMQLPERLSRLGE----TGLLIPLLRLLADGDPVTVQQLSVAAGRTIDEVRLGLAAM..L..DTEYDDQGRIVGQG..
G2G622_9ACTN/6-78                    .....................rk-LATRFTDTV--NRAPGVKLSLLRPLLTLLASGEPVTLDQLAAQADRTVDEIRQALADM..P..DTEYDTAGRIIGNG..
A0A2V5EYY4_9MICC/2-75                .................klapyi------LERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQA..T..STEYDKDGNIIGYG..
A0A346XV98_9ACTN/194-265             .......elvaalgraagqldep------------------QRRVALAIYRLLADRAQVAPEGIADATGINATTIESWLDEW..P..GVFRDPDGRVVGF-w.
A0A3N4A9Y9_9PSED/7-73                ...............ivnrlglt---------------GEAEATLHVALLRELVQGRPVTLKRLAASLNWTTDQVVQVREQL..PcgTVEYDGQGLV----gs
U4L7Y8_PYROM/62-133                  .......................ELVTLFDQN--KGEGGGSMKWLFRPLLQMLTKGEPVTVEDIATTTGKPLDEVKDILSTL..S..SVELDEQGRVVGFG..
A0A1R4FMP8_9MICC/3-76                ....................tid---HQALTYLLSPARSGIDPKLFVPLLRLLAEGEPVTIAELATASGRSEDTVRQGLAAV..P..DTEYDDEGRVIGL-a.
A0A223S7P3_9ACTN/6-78                ..........srfitrvteavrt--------------APGVGFALLRPLLSLLVAGEPVTIAQLATAVGHSEDEIRTALADL..P..DTEYDAQGRIIGYG..
A0A2T0M098_9PSEU/18-90               ................qiastld--------SLFRPETDTAGGWRGLTLLRLLSRGAPVIIGDLTAALGRPAGEVSRALAGT..P..DIEYDDQGRIVGAG..
A0A1V6PPQ7_9EURO/15-80               ...........ksqlladmmaip--------------------DFFPALLRLVSKGEPVPIAALATEVDIPIHDIEQWLHRQ..P..GTDWDGQGRLLGFG..
A0A2S2F8Z4_9GAMM/6-78                .....................ys---KKIAESLSSGNHPEEFATLFVTLLRQLVMGRPVSREALGTALGWSGQRVATVLEPA..P..GTEYDEQGNIIGLG..
A4A3F8_9GAMM/7-75                    ...............iverlglt---------------GEREAALHVTLLRELALGQPVTVERLAKSLNWTTDEAELVLEKL..PcgTIEYDGQGRLIGYG..
A0A0Q2UJA4_MYCGO/3-76                ......................p-LANRLTDLLGSTDNPSSTRWLFRPLLELLAHGQPVTTEQLADATASTVDQMRAALATM..P..DTEYDDRGRIIGNG..
A0A0J6W8G5_9MYCO/2-72                .....................pn-----FLDRLTIPEESGLDPTMLVPLLRLLAAGEPVTVEALAAAVGLPVDEVTRRLAAV..P..DTEYDEQGRIVGQG..
A0A1G5D7R2_9GAMM/16-76               ................pdfgegr--------------------ELVPVLFARLGRGQPVRMAELAEAVAWPEARLRDCLAAW..W..GIRFDESGRIAGF-w.
A0A316TP18_9ACTN/1-68                ......................m-------DRLTTPEETALDLPLLVPLLRLLAAGEPVDVSALAGAAGRTVDEVRARLAAV..P..DTEYDNHGRIIGQG..
I4BSM2_MYCCN/7-78                    ...........tvvstmdsvfsr------------QDSP--AGWLWQPLLRQLARGEPLTIADLAAATGRAGDEVAQAVGRL..R..DTEYDDAGRIVGYG..
A0A2D0A3E5_9BURK/6-79                ......................d-FAALVIDGLSRGSRLEAFAPVFVALLRELAKGSPVSVRVLARASGQSLDQVDAVLRQA..P..DIEYDPAGNIVGYG..
A0A326UC72_9CHLR/9-76                ............ittglieqlqs-----------------EQKELRLLILRRISQGGPVSKAQLASELHISEDGLEKRLHQL..P..DTEYNENGDVVGWG..
A0A2V5F9X2_9MICC/6-78                .....................ys---KKIAESLSSGNHPKEFATLFVALLRQLAMGGPVSREKLAGALGWSGARVATVLEQA..P..GTEYDDEANIIGLG..
G2I8Q9_KOMMN/8-79                    ......................p---TTYIEHFPLISRSQDSAELLVALLRELAKGRPVSRTTLAGILNWPDERIAAVLAQT..A..STEYDDDGNIIGHG..
A0A0F7N5V0_9ACTN/7-78                ......................a-FAARFTTSL--GNAPGLTMPLLRPLLTLLATREPVTISQLAEHAGRSEEDIRHTLACM..P..DTEYDTQGRIIGFG..
A0A1M5B4Y5_9GAMM/9-75                .................nrlglt---------------GEAEATLHVALLRELAQGRPVTLERLAASLNWTTDQVVQVLEQL..PcgTVEYDGQGRLVGYG..
A0A2N7VRE8_9BURK/6-79                .....................sy--ATEIADGLSAIHRRKGSAQFFVVLLREFAKGKAVSRQTLRIALGWPEASDTPMLGAM..P..DIEYDDRGDIVGYG..
A0A097IGF9_9CORY/4-75                .................tdqalt--------YLLSPARSGIDPELFVPLLRLLAEGEPVTVAELATASGRSEDTVRQGLAAV..P..DTEYDDEGRIIGL-a.
G2GNS4_9ACTN/6-78                    .....................qn-LAARFTDTV--NRAPGVKLWLLRPLLTLLATGEPVTVDQLAAQAGRTVDEIREALADM..A..DTEYDTQGRIIGNG..
D4YL19_9MICO/3-76                    .......................ELTTQLPERLNNTEETGLDAVLLIPLLRLIVEGGPVTVEQFAAAAGRPVDAVRTGLAAV..P..DTEYDDQGRIIGQG..
B5EAP1_GEOBB/5-72                    .......tlhdvlaglhcdhprv--------------------WL--FLLRALAKGRPVSRTTIANALNSSLSEIEAALASF..A..DTVYDEKGDVVACG..
A0A411YIA5_9ACTN/52-124              ......tnrlfdavcgtatpste------------------ERAAIRAVYASLRDGEPVTVPRLATTVEWDEARAHELLARL..P..NVERDATGAVIGFG..
C7NGB6_KYTSD/14-83                   ......................d-LSMQLPERLSRLGE----TGLLIPLLRLLADGDPVTVQQLSVAAGRTIDEVRLGLAAM..Q..DTEYDDQGRIVGQG..
A0A328VBB2_9CHLR/9-82                eelveqlaqrwlqqrawqrlrdq-----------------------LPLLRLLALGEPVSWDQLAEELGEPVERVRARLGTW..E..ELVVDEHGHILGAG..
A0A401ZEL1_9CHLR/8-79                ..................alida-----LTERLRASCRGYTK--LWLELLRLLGQGSAVEPGRLAEVMGMTEEALLEQLKEL..P..KIEYNASGQVVAAG..
L7LNN2_9ACTN/6-76                    .................ektlay---------LLSPSRSGLDPSLFVPLLRLLAEGEPVTIAELATASGRSENTVRRGLSSV..P..DAEYDDDGRILGL-a.
D0L7Y2_GORB4/5-74                    ................sipadvf----------ATIAPADRDRALLRAALRLLAHGAPVTVTELAAAAGVDAGDLEET-PIG..A..DIEYDEQGRVLGWG..
A0A260WP56_9NOCA/3-76                .......................DLSTQLPQRLTRPEETGLDAGLLIPLLRLLVDGDPVTVEQLAAAASRTLDDVRRGLAAV..P..DTEYDDQGRIIGQG..
#=GC seq_cons                        ..............................t.h...ttsthtstLhhsLLRLLAcGcPVolspLAsusGhss-cVcpsLsth..s..csEYD-pGRIlGhG..
//
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