GenomeNet

Database: Pfam
Entry: HemX
LinkDB: HemX
Original site: HemX 
#=GF ID   HemX
#=GF AC   PF04375.14
#=GF DE   HemX, putative uroporphyrinogen-III C-methyltransferase
#=GF PI   DUF513; 
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   COG2959
#=GF GA   28.10 28.10;
#=GF TC   28.10 28.10;
#=GF NC   28.00 28.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   3062586
#=GF RT   Nucleotide sequence of the hemX gene, the third member of the
#=GF RT   Uro operon of Escherichia coli K12.
#=GF RA   Sasarman A, Echelard Y, Letowski J, Tardif D, Drolet M;
#=GF RL   Nucleic Acids Res. 1988;16:11835.
#=GF RN   [2]
#=GF RM   16079137
#=GF RT   Protein complexes of the Escherichia coli cell envelope.
#=GF RA   Stenberg F, Chovanec P, Maslen SL, Robinson CV, Ilag LL, von
#=GF RA   Heijne G, Daley DO;
#=GF RL   J Biol Chem. 2005;280:34409-34419.
#=GF DR   INTERPRO; IPR007470;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of bacterial putative uroporphyrinogen-III
#=GF CC   C-methyltransferase proteins. It forms one of the members of a
#=GF CC   complex of proteins involved in the biogenesis of the inner
#=GF CC   membrane in E.coli.  Uroporphorphyrin-III C-methyltransferase
#=GF CC   (HemX) is a single spanning inner membrane protein that
#=GF CC   regulates the activity of NAD(P)H:glutamyl-tRNA reductase (HemA)
#=GF CC   in the tetrapyrrole biosynthesis pathway [1,2].
#=GF SQ   1334
#=GS W1FXE5_ECOLX/32-364       AC W1FXE5.1
#=GS A0A095SFZ7_9GAMM/10-319   AC A0A095SFZ7.1
#=GS A0A0Q6MJV0_9BURK/13-358   AC A0A0Q6MJV0.1
#=GS A0A090V9U2_ESCVU/34-365   AC A0A090V9U2.1
#=GS M5E9Y5_9GAMM/32-357       AC M5E9Y5.1
#=GS D0KW76_HALNC/48-377       AC D0KW76.1
#=GS K5YLT1_9PSED/35-364       AC K5YLT1.1
#=GS A0A0D0SB07_9GAMM/1-195    AC A0A0D0SB07.1
#=GS A0A1A6DVW2_9BURK/15-368   AC A0A1A6DVW2.1
#=GS E3HEH1_ACHXA/36-390       AC E3HEH1.1
#=GS A0A0F4QLD9_9GAMM/273-599  AC A0A0F4QLD9.1
#=GS A0A1U9NDE9_9GAMM/31-360   AC A0A1U9NDE9.1
#=GS Q088L5_SHEFN/75-405       AC Q088L5.1
#=GS C6X7N9_METGS/35-362       AC C6X7N9.1
#=GS A0A127FD61_9GAMM/49-373   AC A0A127FD61.1
#=GS A0A0Q0HFY7_9GAMM/66-398   AC A0A0Q0HFY7.1
#=GS A0A1R3VZN8_9GAMM/32-372   AC A0A1R3VZN8.1
#=GS Q1ZLB0_PHOAS/51-379       AC Q1ZLB0.1
#=GS A0A1W9KYF0_9BURK/33-361   AC A0A1W9KYF0.1
#=GS A0A1G5HS90_9PROT/26-355   AC A0A1G5HS90.1
#=GS A0A0W0VPF4_9GAMM/41-369   AC A0A0W0VPF4.1
#=GS A0A1X1D8E3_9GAMM/32-363   AC A0A1X1D8E3.1
#=GS W0SIP4_9PROT/1-323        AC W0SIP4.1
#=GS A0A063BFQ1_9BURK/320-657  AC A0A063BFQ1.1
#=GS F3GHT2_PSESJ/48-380       AC F3GHT2.1
#=GS A0A0H3KL94_BURM1/322-655  AC A0A0H3KL94.1
#=GS A0A254VPE7_9BURK/13-341   AC A0A254VPE7.1
#=GS A0A1P8JT75_9BURK/40-366   AC A0A1P8JT75.1
#=GS R1H844_9GAMM/38-361       AC R1H844.1
#=GS A0A1Y6D9X1_9GAMM/29-373   AC A0A1Y6D9X1.1
#=GS C4K4E5_HAMD5/27-352       AC C4K4E5.1
#=GS A0A1R4B821_9VIBR/36-367   AC A0A1R4B821.1
#=GS A0A1Q9HH56_9VIBR/60-391   AC A0A1Q9HH56.1
#=GS A0A1T5KTL2_9GAMM/1-312    AC A0A1T5KTL2.1
#=GS L0M8J9_ENTBF/39-370       AC L0M8J9.1
#=GS A0A1F4EGZ4_9PROT/16-342   AC A0A1F4EGZ4.1
#=GS A0A2A6B240_9ALTE/46-382   AC A0A2A6B240.1
#=GS D4XA04_9BURK/35-392       AC D4XA04.1
#=GS Q4K3X5_PSEF5/27-359       AC Q4K3X5.1
#=GS W0B865_9GAMM/37-361       AC W0B865.1
#=GS C3K422_PSEFS/26-357       AC C3K422.1
#=GS A0A090SUA0_9VIBR/54-385   AC A0A090SUA0.1
#=GS A0A158JTX6_9BURK/366-702  AC A0A158JTX6.1
#=GS A0A1I4QH98_9ALTE/25-356   AC A0A1I4QH98.1
#=GS W0HNL8_9GAMM/69-398       AC W0HNL8.1
#=GS A0A1V3I8R7_9PAST/37-375   AC A0A1V3I8R7.1
#=GS A0A142LGK9_9PROT/17-352   AC A0A142LGK9.1
#=GS C7R6S1_KANKD/75-414       AC C7R6S1.1
#=GS A0A1B4VAM0_9GAMM/36-352   AC A0A1B4VAM0.1
#=GS A0A1F4IU77_9BURK/238-383  AC A0A1F4IU77.1
#=GS A0A240UN23_9GAMM/85-412   AC A0A240UN23.1
#=GS K8D9E8_CROSK/1-254        AC K8D9E8.1
#=GS Q3IF71_PSEHT/289-616      AC Q3IF71.1
#=GS A0A1G6LZR7_9BURK/28-369   AC A0A1G6LZR7.1
#=GS G9YXZ2_9ENTR/40-371       AC G9YXZ2.1
#=GS A0A1J0VKJ7_9GAMM/1-324    AC A0A1J0VKJ7.1
#=GS A0A1T0ASZ3_9PAST/73-423   AC A0A1T0ASZ3.1
#=GS A0A0F7M0X0_9GAMM/48-380   AC A0A0F7M0X0.1
#=GS A0A157ZYM6_9BURK/371-707  AC A0A157ZYM6.1
#=GS H0A9Q3_HALSG/8-122        AC H0A9Q3.1
#=GS A0A0L0TKL1_9BURK/38-373   AC A0A0L0TKL1.1
#=GS A0A1I2EIR6_9BURK/27-365   AC A0A1I2EIR6.1
#=GS A0A091AY33_9GAMM/16-343   AC A0A091AY33.1
#=GS A0A1C3EJK5_9GAMM/46-376   AC A0A1C3EJK5.1
#=GS Q82WS0_NITEU/10-334       AC Q82WS0.1
#=GS F9Q8X3_9PAST/33-367       AC F9Q8X3.1
#=GS A0A259R4C6_9GAMM/29-350   AC A0A259R4C6.1
#=GS A0A1I6HBG0_9GAMM/44-386   AC A0A1I6HBG0.1
#=GS A0A1D3RQ91_9BACT/26-379   AC A0A1D3RQ91.1
#=GS A0A1T1GT33_OCELI/1-140    AC A0A1T1GT33.1
#=GS Q15Z17_PSEA6/112-450      AC Q15Z17.1
#=GS A0A177MYX0_9GAMM/21-365   AC A0A177MYX0.1
#=GS A0A1H7W0W5_9GAMM/15-216   AC A0A1H7W0W5.1
#=GS A0A077FFL6_9PSED/27-359   AC A0A077FFL6.1
#=GS A0A0M2KC58_9GAMM/30-361   AC A0A0M2KC58.1
#=GS A0A0D5LHW5_9BURK/326-662  AC A0A0D5LHW5.1
#=GS A0A1A8T196_9GAMM/50-392   AC A0A1A8T196.1
#=GS Q7MYN0_PHOLL/32-363       AC Q7MYN0.1
#=GS J6CJ65_PASMD/4-48         AC J6CJ65.1
#=GS C3X715_OXAFO/23-359       AC C3X715.1
#=GS D3HP38_LEGLN/34-363       AC D3HP38.1
#=GS Q8XWW4_RALSO/348-690      AC Q8XWW4.1
#=GS A0A0S8YUC3_9PSED/29-361   AC A0A0S8YUC3.1
#=GS A0A0H2LZM9_VARPD/41-364   AC A0A0H2LZM9.1
#=GS G2IUI9_PSEUL/15-342       AC G2IUI9.1
#=GS A0A0T2YKY6_9BURK/33-238   AC A0A0T2YKY6.1
#=GS A0A1C2G2D2_9GAMM/24-334   AC A0A1C2G2D2.1
#=GS V5AF96_9PROT/106-320      AC V5AF96.1
#=GS M5CTE9_STEMA/11-325       AC M5CTE9.1
#=GS A0A1I6JTY5_9ALTE/27-366   AC A0A1I6JTY5.1
#=GS M4R4X4_BIBTR/77-424       AC M4R4X4.1
#=GS G8LKV9_ENTCL/38-369       AC G8LKV9.1
#=GS A0A0G3LMY4_XANCT/12-213   AC A0A0G3LMY4.1
#=GS F6AGQ6_PSEF1/30-362       AC F6AGQ6.1
#=GS A0A1Y6IW95_9VIBR/46-377   AC A0A1Y6IW95.1
#=GS A0A1A9MY26_9BURK/337-671  AC A0A1A9MY26.1
#=GS A0A1X9NJI7_9GAMM/29-366   AC A0A1X9NJI7.1
#=GS Q0AH87_NITEC/10-336       AC Q0AH87.1
#=GS A0A0Q8F2R3_9GAMM/10-205   AC A0A0Q8F2R3.1
#=GS K8WXY8_9GAMM/32-362       AC K8WXY8.1
#=GS A0A0Q0C2C5_PSESX/72-404   AC A0A0Q0C2C5.1
#=GS A0A1S1MUP8_9GAMM/274-600  AC A0A1S1MUP8.1
#=GS A0A1T1AQM5_RHOFE/40-360   AC A0A1T1AQM5.1
#=GS A0A1F4ET87_9PROT/15-343   AC A0A1F4ET87.1
#=GS W1HY39_KLEPN/34-89        AC W1HY39.1
#=GS A0A1S2CER2_9ALTE/24-357   AC A0A1S2CER2.1
#=GS A0A0F4NFJ3_9VIBR/62-393   AC A0A0F4NFJ3.1
#=GS V9H6K6_9NEIS/44-378       AC V9H6K6.1
#=GS A0A149W050_9PROT/14-327   AC A0A149W050.1
#=GS A0A0F3IKC9_9GAMM/21-362   AC A0A0F3IKC9.1
#=GS A0A135IAU9_9GAMM/77-404   AC A0A135IAU9.1
#=GS G2GYS1_9ENTR/29-362       AC G2GYS1.1
#=GS A0A0W1RT02_9GAMM/150-492  AC A0A0W1RT02.1
#=GS A0A1N7MKD5_9GAMM/128-476  AC A0A1N7MKD5.1
#=GS A0A256CSN9_9GAMM/585-904  AC A0A256CSN9.1
#=GS A0A1M5ZF23_9VIBR/53-384   AC A0A1M5ZF23.1
#=GS Q9K044_NEIMB/27-375       AC Q9K044.1
#=GS A0A1R1MHD2_9GAMM/62-407   AC A0A1R1MHD2.1
#=GS A0A1C3K8P0_9BURK/66-422   AC A0A1C3K8P0.1
#=GS W0HGZ8_9GAMM/69-398       AC W0HGZ8.1
#=GS F3L5T3_9GAMM/97-438       AC F3L5T3.1
#=GS A0A0J9BIW4_9BACT/32-363   AC A0A0J9BIW4.1
#=GS K0CKP0_ALCDB/9-325        AC K0CKP0.1
#=GS A0A1Y6G1V0_9GAMM/40-389   AC A0A1Y6G1V0.1
#=GS A0A0B1YT40_9BURK/321-655  AC A0A0B1YT40.1
#=GS A0A1D8YAK5_9GAMM/15-210   AC A0A1D8YAK5.1
#=GS C4SGB4_YERMO/35-366       AC C4SGB4.1
#=GS X2H5T1_9GAMM/63-368       AC X2H5T1.1
#=GS A0A1S2TYV9_9GAMM/40-362   AC A0A1S2TYV9.1
#=GS W0QCK7_9PAST/74-416       AC W0QCK7.1
#=GS A0A258YZL2_9PROT/15-335   AC A0A258YZL2.1
#=GS A0A161XYQ6_9GAMM/282-608  AC A0A161XYQ6.1
#=GS A6F226_9ALTE/27-357       AC A6F226.1
#=GS A0A0K8P436_IDESA/59-410   AC A0A0K8P436.1
#=GS F5S6H9_9NEIS/58-401       AC F5S6H9.1
#=GS A0A258P1U5_9BURK/24-369   AC A0A258P1U5.1
#=GS A0A1Y2ZVM1_9GAMM/21-351   AC A0A1Y2ZVM1.1
#=GS I4VPX7_9GAMM/2-296        AC I4VPX7.1
#=GS A0A0L0ASW6_9ENTR/33-364   AC A0A0L0ASW6.1
#=GS E6KZP5_9PAST/88-430       AC E6KZP5.1
#=GS A0A0A0EQC7_9GAMM/21-218   AC A0A0A0EQC7.1
#=GS A0A090U4W8_9VIBR/53-319   AC A0A090U4W8.1
#=GS I1XF49_METNJ/29-342       AC I1XF49.1
#=GS A0A0S8B7F4_9PROT/36-365   AC A0A0S8B7F4.1
#=GS A0A090P4U5_9VIBR/1-82     AC A0A090P4U5.1
#=GS A4BAQ0_9GAMM/45-359       AC A4BAQ0.1
#=GS A0A063Y7K9_9GAMM/1-319    AC A0A063Y7K9.1
#=GS Q63W72_BURPS/323-659      AC Q63W72.1
#=GS A0A1H4BAA5_9BURK/38-375   AC A0A1H4BAA5.1
#=GS A0A0K2E0V3_PISSA/148-321  AC A0A0K2E0V3.1
#=GS B2VG53_ERWT9/32-363       AC B2VG53.1
#=GS A0A1G3EUY9_9GAMM/30-324   AC A0A1G3EUY9.1
#=GS F3KX66_9BURK/46-391       AC F3KX66.1
#=GS A0A0R2UBW7_9GAMM/47-382   AC A0A0R2UBW7.1
#=GS M7CKC5_9ALTE/1-329        AC M7CKC5.1
#=GS A0A1I2JD65_9GAMM/36-368   AC A0A1I2JD65.1
#=GS A0A1E7RLZ8_9GAMM/14-322   AC A0A1E7RLZ8.1
#=GS A0A1N6X5M9_9GAMM/58-382   AC A0A1N6X5M9.1
#=GS A0A119V080_9BURK/322-657  AC A0A119V080.1
#=GS H3RIV6_PANSE/33-364       AC H3RIV6.1
#=GS A0A0B4XFN9_9GAMM/30-342   AC A0A0B4XFN9.1
#=GS A0A0R2T4S6_9GAMM/59-458   AC A0A0R2T4S6.1
#=GS A0A0Q6XNQ1_9BURK/1-335    AC A0A0Q6XNQ1.1
#=GS A0A1G2MXY2_9BACT/19-152   AC A0A1G2MXY2.1
#=GS A0A1W9NGR4_9GAMM/39-388   AC A0A1W9NGR4.1
#=GS A0A1I4PI60_9PROT/60-236   AC A0A1I4PI60.1
#=GS A4JGV3_BURVG/321-659      AC A4JGV3.1
#=GS A0A165J4M7_9BURK/24-361   AC A0A165J4M7.1
#=GS R4YSG1_OLEAN/35-353       AC R4YSG1.1
#=GS U3HBU6_PSEAC/27-359       AC U3HBU6.1
#=GS A0A1I5PV42_9PSED/30-362   AC A0A1I5PV42.1
#=GS A0A2G2A2R2_9COXI/21-336   AC A0A2G2A2R2.1
#=GS A0A1F4H7F5_9BURK/37-235   AC A0A1F4H7F5.1
#=GS A0A1W6Z1E1_9BORD/44-398   AC A0A1W6Z1E1.1
#=GS A0A1G6SW15_9BURK/35-359   AC A0A1G6SW15.1
#=GS A0A0J1GNP8_9GAMM/55-386   AC A0A0J1GNP8.1
#=GS A0A010SFG5_PSEFL/27-358   AC A0A010SFG5.1
#=GS A0A1G9TEY4_9BURK/22-355   AC A0A1G9TEY4.1
#=GS A6TGI6_KLEP7/34-365       AC A6TGI6.1
#=GS A0A011MTS1_9PROT/19-356   AC A0A011MTS1.1
#=GS A0A1A6C4U0_9GAMM/54-384   AC A0A1A6C4U0.1
#=GS A0A261UE79_9BORD/45-402   AC A0A261UE79.1
#=GS W4B0N8_9BACL/19-134       AC W4B0N8.1
#=GS A0A0W0ZRC5_9GAMM/39-362   AC A0A0W0ZRC5.1
#=GS A0A1Q8J2D3_9BURK/333-668  AC A0A1Q8J2D3.1
#=GS S2KI99_HALAF/164-493      AC S2KI99.1
#=GS B4E8C3_BURCJ/322-655      AC B4E8C3.1
#=GS A0A0J5P827_9PAST/70-412   AC A0A0J5P827.1
#=GS A0A1J0TAE3_9ALTE/65-404   AC A0A1J0TAE3.1
#=GS A0A098U683_9BURK/49-389   AC A0A098U683.1
#=GS A0A0Q6Z0H7_9BURK/39-377   AC A0A0Q6Z0H7.1
#=GS A0A1Y5K5I2_9GAMM/284-611  AC A0A1Y5K5I2.1
#=GS H0J1I6_9GAMM/131-470      AC H0J1I6.1
#=GS A0A1V3THR7_9PAST/73-416   AC A0A1V3THR7.1
#=GS A0A1Z9KP53_9GAMM/27-349   AC A0A1Z9KP53.1
#=GS A0A1I0PZU1_9GAMM/37-357   AC A0A1I0PZU1.1
#=GS A0A0F7K1L1_9GAMM/50-391   AC A0A0F7K1L1.1
#=GS A4BU04_9GAMM/1-347        AC A4BU04.1
#=GS G8QPT0_DECSP/38-361       AC G8QPT0.1
#=GS A0A151JJ58_9VIBR/59-390   AC A0A151JJ58.1
#=GS C6WYU9_METML/16-344       AC C6WYU9.1
#=GS A0A254TL19_9BURK/39-381   AC A0A254TL19.1
#=GS A0A193LC00_9GAMM/52-399   AC A0A193LC00.1
#=GS A0A080K9R7_9GAMM/13-166   AC A0A080K9R7.1
#=GS A0A0L8AZB4_9BURK/23-347   AC A0A0L8AZB4.1
#=GS A0A1G7T869_9GAMM/173-504  AC A0A1G7T869.1
#=GS W9T170_9PSED/35-204       AC W9T170.1
#=GS E1VFU3_9GAMM/31-375       AC E1VFU3.1
#=GS A0A1H7GPM0_9BURK/23-372   AC A0A1H7GPM0.1
#=GS A0A1Y0KXB0_9PSED/28-360   AC A0A1Y0KXB0.1
#=GS A0A1F1QCN4_9PSED/27-359   AC A0A1F1QCN4.1
#=GS A0A0M9GFG6_9PSED/27-359   AC A0A0M9GFG6.1
#=GS S6B1X0_PSERE/29-361       AC S6B1X0.1
#=GS A0A1X1QRY6_9GAMM/39-367   AC A0A1X1QRY6.1
#=GS A0A1H7NHR9_9PSED/36-375   AC A0A1H7NHR9.1
#=GS A0A1V4LMG0_9PSED/28-360   AC A0A1V4LMG0.1
#=GS E5ANG7_PARRH/562-896      AC E5ANG7.1
#=GS N6Y1Z6_9RHOO/38-382       AC N6Y1Z6.1
#=GS A0A1V9DLT5_9GAMM/33-364   AC A0A1V9DLT5.1
#=GS F7NYJ5_9GAMM/39-372       AC F7NYJ5.1
#=GS A0A0W1AJX9_9GAMM/34-365   AC A0A0W1AJX9.1
#=GS H8L228_FRAAD/16-339       AC H8L228.1
#=GS A0A071M1B2_9ENTR/39-370   AC A0A071M1B2.1
#=GS A0A0Q9YYM1_9COXI/131-452  AC A0A0Q9YYM1.1
#=GS A0A1U9RDY1_9GAMM/137-477  AC A0A1U9RDY1.1
#=GS A0A060NL06_9BURK/248-367  AC A0A060NL06.1
#=GS A0A0Q4QLB5_9GAMM/11-325   AC A0A0Q4QLB5.1
#=GS A0A154R5G4_9GAMM/35-356   AC A0A154R5G4.1
#=GS A0A0S2TAA3_9GAMM/50-399   AC A0A0S2TAA3.1
#=GS A1SAQ2_SHEAM/34-361       AC A1SAQ2.1
#=GS A0A091B534_9GAMM/18-163   AC A0A091B534.1
#=GS A0A2A2DU62_9PSED/32-364   AC A0A2A2DU62.1
#=GS U1ZSQ7_9BURK/44-393       AC U1ZSQ7.1
#=GS A0A0W0NVY4_9PSED/27-359   AC A0A0W0NVY4.1
#=GS A0A1I0FEN3_9ALTE/21-357   AC A0A1I0FEN3.1
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D4GX69_HALVD/5-127                   ......................................................................................................................grs----LNLG.L..V...V..I....V..V...L...L..T....A..G..AV..........gAT.M....F.Y..Q.....YS.V...D.S.L.D.QQN................EQLR.ERN.A.A.L..EE.N.L.SQ...........................................................--.-.S..R....Q...N..L..S.A.T.R.T.EL.REL........ND.S.L....E....R.T.R....G....D...V.......S.Q...V....S...DS......L.E...........D....T....E.S....Q....L.SST.QNE.............lSST.RDEL..Q......ET..ESNLEDAR-----------------------.--..-.....---....-----------------..-..-..--..--.---------------...--..-................--.....-......-........-.......-.......-.....-.......-.......-.......-...-.-.....-......-....--...-..---.......................................--...-..-...-...-...-....-......-.......-...-....-.......-.......-...-...-...-...-...-...-...-------....---...--.----....--------------------------...------------------.---.-.---------------.-.---.-.-.----..-.-.-.---------------srise...........................
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G8M5R1_9BURK/358-694                 .......................................................................................................................hr--GGVGIV.L..L...W..L....V..V...V...I.lA....V..A..AG..........aGA.F....V.L..N.....RK.F...-.-.-.D.RAD................TQLS.QRL.A.Q.A..DE.Q.N.AD...........................................................LR.A.K..A....D...Q..A..-.-.-.A.S.AT.TTL........NT.Q.I....I....Q.L.Q....G....K...L.......A.D...A....E...AH......S.Q...........A....L....Q.Q....Q....Y.QD-.LAS..............NRD.DWTV..A......EV..EQILSSASQQLQLTGNVQLALFALQSADERL.AS..T.....TGP....QVVAIRKAIAADIDKLK..S..A..PT..TD.LTGLAIKLDTAIDQI...GQ..L................PL.....S......G........E.......A.......P.....I.......E......rA.......R...A.Q.....A......A....EP...A..DSAsia.................................aatGE...P..R...W...K...V....L......W.......R...Q....It....ggI.......G...Q...Q...L...S...S...L...VSVRRID....NAD...AM.LTSP....DQGYFVRENVKLRLLSARLSLLSRSE...PTLKSDLRAADAALARYF.DAS.S.KKVQAVRDLVKQVDQ.A.SLA.V.A.VPNL..N.A.S.LAAVHQ---------fkr.............................
A0A091C0X1_9GAMM/17-337              ....................................................................................................................ragll------SW.L..L...A..A....I..V...V...V..A....L..G..AG...........GW.W....-.A..W.....QR.F...A.P.A.D.ESGpd...........lspEALD.ARL.L.D.A..EL.-.-.-A...........................................................LS.G.L..R....R...N..Q..Q.G.I.E.Q.RL.TDT........HA.R.T....G....L.L.R....E....E...V.......L.G...V....S...QR......A.A...........I....L....E.D....N....L.REL.SAQa...........aeGSE.SLRL..D......EV..ELLLGLAQARLAIAGDTAGAIRASQLALQAL.AP..L.....TDP....QYINVRQTLGQELAALR..A..L..PD..DP.RDQAAGELDALEATL...PR..L................SS.....R......A........P.......G.......T.....P.......P.......-.......-...-.-.....-......-....--...A..AGD.......................................SG...S..R...W...Q...R....L......L.......D...A....-.......-.......-...-...-...-...-...-...I...V--QVRP....SSS...QD.LISP....ADRATGEATLALELALARTALERRDD...TAFRASLQRIDQWLQRLY.-AD.D.ALLRERRERLAALAK.Q.PLA.P.A.LPDQ..G.A.A.LQQLRDLRRGR----dat.............................
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Q329X8_SHIDS/33-364                  .....................................................................................................................nnpa----LILS.A..V...A..I....A..I...A...L..A....A..G..VG...........LY.G....W.G..K.....QQ.A...V.N.Q.T.ATS................DALA.NQL.T.A.L..QK.A.Q.ES...........................................................--.-.-..-....-...Q..K..A.E.L.E.G.II.KQQ........AA.Q.L....K....Q.A.N....R....Q...Q.......E.T...L....A...KQ......L.D...........E....V....Q.Q....K....V.ATI.SGS..............DAK.TWLL..A......QA..DFLVKLAGRKLWSDQDVTTAAALLKSADASL.AD..M.....NDP....SLITVRRAITDDIASLS..A..V..SQ..VD.YDGIILKLNQLSNQV...DN..L................RL.....A......D........N.......D.......S.....D.......G.......S.......P...M.D.....S......N....GE...E..LSS.......................................SI...S..E...W...R...I....N......L.......Q...K....S.......W.......Q...N...F...M...D...N...F...ITIRRRD....DTA...VP.LLAP....NQDIYLRENIRSRLLVAAQAVPRHQQ...ETYRQALENVSTWVRAYY.DTD.D.ATTKAFLDEVDQLSQ.Q.NIS.M.D.LPET..L.Q.S.QAMLEKLMQTRVRN-l...............................
A0A1X3CVE8_9NEIS/99-431              ........................................................................................................................q-SSGRAVA.V..V...A..L....A..F...S...L.lA....L..G..AG...........GF.L....F.V..Q.....GQ.N...-.L.L.K.TQE................MDFN.QKI.D.K.A..AL.G.E.SQ...........................................................--.-.N..A....A...L..L..Q.E.I.L.R.KQ.NNN........QN.V.L....D....Q.I.V....G....N...Q.......K.Q...N....A...DK......I.A...........A....A....N.K....A....Y.QEL.L-K..............GRA.DWLV..D......ET..ETMLNMGSQQLLLTGNVPAAVNVLENIESRL.SR..F.....DHP....ELLPIKQAVSADLTALK..N..R..PY..LD.VSAVSLRLDRLETAV...AG..L................PL.....M......V........D.......G.......A.....L.......K.......P.......G...Q.T.....A......Q....PA..aA..PAA.......................................NL...S..W...W...E...N....A......W.......Q...K....-.......T.......L...A...A...L...K...G...M...VEVRRLD....NND...AM.LIAP....EQVYFVRENLRLRLLDARTALLQHNG...EVYLNDLNNAETAVKQYF.DTA.S.PATQSWLRELGELKA.L.DLR.S.V.SDDV..LkN.S.LNAVRNY--------qevvrp..........................
A0A1J5MNZ4_9GAMM/79-415              .....................................................................................................................tpis-----KLA.I..L...C..L....I..L...V...L..L...lA..G..VA...........GY.G....V.D..K.....YL.K...-.E.Q.V.AQQak............idALVA.KQS.S.V.I..DE.I.T.T-...........................................................--.Q.L..N....Q...Q..V..K.E.L.Q.T.RN.QSL........TQ.K.L....T....DnV.E....T....Q...L.......A.S...Q....Q...QS......Q.T...........L....I....N.Q....K....I.AEL.SGR..............RPS.DWLL..A......EA..NYLVTIAGRKLWQEKDQKTAAALLATADKRI.AE..M.....HDE....SLIDIRRALAKDIATLS..A..L..PQ..DK.SQDIALAIDGLITQV...DN..L................KL.....N......T........V.......T.......L.....P.......D.......-.......-...A.I.....E......D....DV...Q..QSA.......................................AD...A..S...W...Q...D....N......L.......R...Q....T.......W.......Y...N...F...I...D...G...M...ITIRKRE....SNV...VP.LMSA....KQRWYLEENLKNKLVQAQLAVYRKQQ...QAFTSSIEVSRTWVLQFF.DRE.D.SATTFMLDELAKLEK.A.SIA.V.S.YPRD..L.L.S.RNLIGDEVVRR----niss............................
B4F1X1_PROMH/34-368                  ........................................................................................................................k-RSGLIGS.A..V...A..I....L..V...I...L..A....I..G..GG...........LY.Y....Y.T..T.....QQ.A...T.K.L.S.TEN................QSLK.SQL.A.Q.L..QQ.L.Q.DT...........................................................--.-.Y..Q....Q...R..F..D.N.I.D.S.QF.NSQ........KL.T.I....D....K.L.Q....N....E...R.......Q.V...T....E...RQ......I.Q...........N....L....Q.T....Q....F.AAI.SSA..............DVK.SWLL..A......QA..DFMVKMAGRKLWNDQDVVTAVSLLKGADSSL.AE..M.....NDP....SLLAIRRAINEDIGNLA..A..L..SK..ID.NDGTILQLNQLANQV...DN..L................RL.....S......G........F.......E.......R.....D.......G.......S.......P...M.D.....K......N....DE...A..ISG.......................................SL...S..D...W...K...Q....N......L.......S...K....S.......W.......K...S...F...M...D...D...F...ITIRRRD....STA...IP.LLAP....NQDIYLRENIRSRLLIASQAVPRHQT...EIYQQSLEAVSTWVRAYF.DTT.D.PNTTAFLDSINELEK.Q.PIT.L.A.MPTE..L.K.S.LSLLEKRVEKQIRN-l...............................
A0A198FPZ6_9GAMM/34-368              ........................................................................................................................k-RSGLIGS.A..V...A..I....F..V...I...L..A....I..G..GG...........FY.Y....Y.A..H.....QQ.S...S.K.L.S.LEN................QALK.SEL.A.E.I..QQ.R.Q.NT...........................................................--.-.V..Q....Q...R..F..D.N.I.D.S.LL.NSQ........KQ.T.I....E....Q.L.Q....N....D...N.......Q.I...T....E...QQ......L.Q...........K....L....Q.N....Q....F.SAI.SSA..............DVK.SWLL..A......QA..DFMVKMAGRKLWNDQDVVTAVSLLKGADSSL.AE..M.....NDP....SLFNIRQAINEDIANLA..A..L..TK..ID.NDGIILQLNQLANQV...DN..L................RL.....S......G........L.......E.......R.....N.......G.......S.......P...M.D.....K......N....DE...A..ISG.......................................SL...S..D...W...K...E....N......L.......S...K....S.......W.......K...G...F...M...D...D...F...ITIRRRD....TAT...TP.LLAP....NQDIYLRENIRSRLLIASQAIPRQQT...EIYQQSLEAVSTWVRAYF.DTT.D.PATQAFLDTLSELEK.Q.PIT.L.A.MPTE..L.K.S.PALLEKRVEKQIRN-l...............................
A0A1H4F7B7_9GAMM/33-364              .......................................................................................................................qr--YGVLLG.A..A...A..I....V..I...A...L..G....L..S..GG...........VY.Y....Y.A..H.....QQ.T...S.K.Q.S.AIV................AQLQ.EQL.D.G.F..KQ.Q.Q.QQ...........................................................--.-.-..-....-...N..Q..Q.S.W.Q.Q.SL.AQQ........SQ.T.Q....N....A.S.E....Q....R...L.......T.A...L....N...SQ......V.G...........D....L....Q.E....K....L.DAL.SNH..............DAK.TWLL..S......EA..DFLVKMAGRKLWADKDVTTAGTLLKSADASL.AE..M.....KDP....SLIDLRRAITQDISTLA..S..V..NQ..VD.FDGIILKVNQLADQV...DN..L................RM.....A......D........S.......D.......L.....D.......E.......A.......P...M.D.....E......N....DT...S..LSA.......................................SW...S..E...W...R...Q....N......L.......S...K....S.......W.......H...N...F...L...S...E...F...ITVRRRD....SGA...EP.LLAP....NQDIYLRENIRARLLVAAQAVPRHQN...ETYRQSLETAAVWVRAYF.DNN.D.AATKAFLEQLDALSQ.Q.SVS.M.D.VPTE..L.Q.S.QPLLEKVMQTRVRN-l...............................
F0G4V4_9BURK/2-312                   .................................................................................................................alnrkvdr--------.-..-...-..-....-..-...-...-..-....-..-..--...........--.-....-.-..-.....--.-...-.-.-.-.---................--LD.DAL.V.A.R..QK.A.L.DA..........................................................qTA.E.T..R....T...K..T..E.Q.A.L.A.SA.HQV........DT.Q.L....A....Q.L.D....G....K...L.......A.D...A....Q...NA......Q.Q...........A....L....Q.Q....Q....Y.QD-.LSR..............NRD.AWML..E......EV..DQMLSSASQQLQLTGNTQLALIALQNADARL.AT..S.....QSA....QAVTVRKALAQDIEKLK..A..A..PS..AD.LTGLAIKLDDAIGKI...DA..L................PL.....A......G........E.......A.......I.....V.......Ph.....aA.......P...K.A.....V......E....PT...A..ASAav...................................aaGE...P..R...W...K...V....W......W.......H...Df.saG.......L.......G...Q...Q...L...K...G...L...VQVRRID....NAD...AM.LASP....DQGYFVRENVKLRLLTARLSLLARNE...SAMKADLHAAQASLGKYF.DQA.S.KDTQTVEDLLKQVDG.A.SLT.V.A.VPNL..N.T.S.LNAVQQF--------ksr.............................
A0A2D8R8Q8_9GAMM/88-433              ......................................................................................................................wpl-----WLA.F..L...L..L....L..I...A...L..G....-..A..AG...........WY.A....W.D..H.....LK.S...-.-.L.R.SDI...............dQSVE.SQL.S.K.V..ES.T.T.QQ...........................................................--.-.V..R....S...D..Q..S.A.F.T.S.SM.SNL........QQ.Q.L....Q....N.Y.D....Q....R...I.......D.E...L....S...AQ......L.D...........K....T....A.Q....Q....L.LAD.QAT..............SRT.DWLL..A......EA..EYLLRLANQRVLLEKDVESALAILIAADEAL.KE..T.....DEV....AVIPIRKTIASEMLALK..S..L..GE..VD.VTGAYLKLEALAQQV...AS..Mdesl.......mlkesPL.....A......K........Q.......T.......M.....E.......S.......G.......-...-.-.....-......-....--...-..--Eglvinpdae.....................qadtdtqeqAE...Q..P...W...Y...T....K......A.......L...S....T.......A.......Q...D...T...L...N...R...F...VIVRNLD....EPI...AP.LLAP....EQTHYLRQNLRLMIEQAELALLEQNQ...AIFSNSLEKAEKWIRSYF.VAD.S.SQTKALLDSIESLKA.I.SVD.P.E.LPDI..S.A.S.LRQLKGLLES-----vyq.............................
F4G3X6_ALIDK/23-359                  ......................................................................................................................ssg--SGAALF.T..L...S..V....I..S...M...A..A....L..V..GS...........AL.L....W.Q..R.....LS.S...-.-.-.-.-IQ................EQLA.RQT.A.D.S..GA.Q.A.IE...........................................................AR.A.L..A....Q...Q..A..Q.D.L.A.R.DT.SAR........LA.V.A....E....A.R.V....G....E...V.......A.L...Q....R...SQ......L.E...........E....L....M.Q....S....L.SR-.---..............SRD.ENLV..V......DI..DAGLRLAQQQAQLTGSLQPLVAALRSASQRI.ER..A.....AQP....RLAPVQRAMGQDLERLE..H..A..SV..TD.TAGLLGRLDDLVRQV...DD..L................PL.....V......S........G.......V.......A.....Q.......A.......A.......A...M.R.....H......Qa..gNG...Q..PAAaaa.................................aaaSE...P..R...W...Q...A....A......L.......R...R....T.......W.......EgvrD...E...T...R...G...L...VRVSRID....HPD...AM.LLAP....DQAFFLRENLKLKLLNARLALLARRM...DSARTDLAAATAALNKYF.DPA.S.RRTQNAATALQQLQS.H.TKA.A.E.TPQL..D.D.T.FAALAT---------aaagr...........................
A0A158EQ08_9BURK/399-735             ....................................................................................................................rggga---GTALL.W..L...V..L....L..I...V...V..V....V..A..GV...........GG.F....M.L..N.....RK.F...-.-.-.D.QRD................AQFA.QRL.Q.A.N..DT.Q.T.DA...........................................................--.-.L..R....A...Q..A..D.Q.A.A.S.SV.QAL........NT.Q.I....I....Q.F.Q....G....K...L.......T.D...A....Q...AQ......S.Q...........A....L....Q.Q....Q....Y.QD-.LAS..............NRD.DWTL..A......EV..EQILSSASQQLQLTGNVQLALFALQSADTRL.AA..T.....TGP....QIVTIRKAIAQDMEKLR..A..T..PS..TD.LTGLAIKLDTAIDQI...DS..L................PL.....A......G........E.......A.......P.....I.......A.......Q.......P...T.A.....H......A....DT...P..RDTasiaa.............................atgqpYW...K..V...W...L...Q....Q......L.......A...S....G.......I.......G...Q...Q...L...S...S...L...VTVRRID....NAD...AM.LASP....DQGYFVRENVKLRLLSARLSLLSRSE...PSLKSDLHAADTALGRYF.DQS.S.GKVKAVRTLLQQVDQ.A.SLA.V.T.VPDL..N.A.S.LAAVHQ---------fkr.............................
A0A286BT06_9ENTR/32-363              ........................................................................................................................k-SDGKVLS.A..V...A..I....V..I...A...L..A....I..G..AG...........LY.L....N.G..K.....HQ.A...D.L.Q.A.QTN................QNLS.EQL.S.A.L..QQ.Q.L.GS...........................................................--.-.-..-....-...D..K..Q.Q.L.T.Q.QL.DNA........SS.A.L....Q....E.T.R....T....L...Q.......D.N...S....A...KE......L.E...........T....L....R.D....K....V.ATI.SGN..............DTR.TWLL..A......QA..DYLVKLAGRKLWSDQDVTTAAALLKSADTSL.AD..M.....NDP....SVMNVRRALTQDISSLS..A..V..SQ..ID.YDGTILKLNQLSNGV...DN..L................RL.....A......D........N.......D.......S.....D.......D.......S.......P...M.D.....A......D....GG...E..LSS.......................................SL...H..E...W...R...Q....N......L.......V...K....S.......W.......H...N...F...M...D...D...F...ITIRRRD....NTA...QP.LLAP....NQDVYLRENIRSRLLIAAQAVPRHQD...EIYKQSIDAVSTWVRAWY.DTN.D.AATKAFLTQLDELSQ.Q.SIS.M.D.VPDT..L.E.S.QPLLEKLMQTRVRN-l...............................
A0A0E9M4T8_9PROT/44-374              ..................................................................................................................snlsigq--------.-..M...T..L....T..L...V...L..A....I..F..VW...........QW.F....D.A..H.....HQ.L...-.-.-.N.TLQ................QELA.KRL.T.E.M..DG.N.N.KA...........................................................NQ.V.L..V....K...Q..S..Q.E.S.L.S.AL.TNK........VT.A.L....E....S.A.N....A....E...A.......Q.S...E....R...AA......L.E...........T....L....Y.Q....E....M.SS-.---..............NRD.ETAL..A......EV..EQMLMIASQQLQLSANVKAALIAMQQADGRL.QR..M.....DRP....ALNNLRKSINGDMDRLR..T..L..PA..VD.TAGITLRLDNLIVAA...EI..I................PLn..heV......S........Q.......T.......T.....S.......A.......K.......P...T.M.....L......T....PI...T..TPT.......................................NE...N..S...W...Q...H....L......W.......R...E....-.......I.......W...Q...E...A...R...N...M...VRIEDMR....KRE...MP.LLSP....TESFFLRENLKLRLLSARLALLSRDE...TSFRNDLKAAADWVKRYF.DAN.S.TDGKQALTALQKMST.A.NIN.I.E.LPDI..N.G.S.IEAVRAY--------rmahekak........................
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Y602A_HAEIN/1-145                    ....................................................................................................................mxvnf--------.-..-...-..-....-..-...-...-..-....-..-..--...........--.-....-.-..-.....--.-...-.-.-.-.---................----.---.-.-.-..--.-.-.--...........................................................--.-.-..-....-...-..-..-.-.-.-.-.--.---........--.-.-....-....-.-.-....-....-...-.......-.-...-....-...--......-.-...........-....-....-.-....-....-.---.---..............---.----..-......--..-------------------------------.--..-.....---....-----------------..-..-..--..--.---------------...--..-................--.....-......-........-.......-.......-.....D.......-.......-.......E...T.S.....K......N....ND...K..LSN.......................................NI...T..D...W...Q...Q....N......I.......E...K....S.......A.......T...S...F...L...N...H...F...IRISPKQ...nSNK...KE.LLAP....NQDIYLRENIRLRLQLAIMAVPRQQN...ELYKQSLEAVSSWVRSYF.DTN.A.EVTQNFLKLVDGLTD.T.SIY.V.D.VPEQ..L.K.S.LTLLDKYLNRTA---ldv.............................
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