GenomeNet

Database: Pfam
Entry: Herpes_UL56
LinkDB: Herpes_UL56
Original site: Herpes_UL56 
#=GF ID   Herpes_UL56
#=GF AC   PF04534.12
#=GF DE   Herpesvirus UL56 protein
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF SE   DOMO:DM04377;
#=GF GA   25.00 25.00;
#=GF TC   36.30 37.30;
#=GF NC   23.00 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12050385
#=GF RT   Identification and characterization of the UL56 gene product of
#=GF RT   herpes simplex virus type 2. 
#=GF RA   Koshizuka T, Goshima F, Takakuwa H, Nozawa N, Daikoku T, Koiwai
#=GF RA   O, Nishiyama Y; 
#=GF RL   J Virol 2002;76:6718-6728.
#=GF DR   INTERPRO; IPR007620;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   In herpes simplex virus type 2, UL56 is thought to be a
#=GF CC   tail-anchored type II membrane protein involved in vesicular
#=GF CC   trafficking.  The C terminal hydrophobic region is required for
#=GF CC   association with the cytoplasmic membrane, and the N terminal
#=GF CC   proline-rich region is important for the translocation of UL56
#=GF CC   to the Golgi apparatus and cytoplasmic vesicles [1].
#=GF SQ   5
#=GS UL56_HHV2H/1-197         AC P28282.1
#=GS Q7T5C6_CHV1/16-191       AC Q7T5C6.1
#=GS Q2QBB9_CHV16/17-191      AC Q2QBB9.1
#=GS A0A060Q5A6_9ALPH/45-248  AC A0A060Q5A6.1
#=GS UL56_HHV11/1-196         AC P10240.1
UL56_HHV2H/1-197                    .............MALGAGHAHACRDDGDDSVIDAPPPYESVAGA.SAGQFVVIDIDTPTDSPPPYSAGTSPVGLVSPASSGDGEVCERGR.SRRAAWRAARRARRRAERRARRRSFGP..GGLFVETPLFLPETMIGAHPGVGGDLPSGLPTYAEATSDRPPTYAMVMAACPTE....PPGGSV..GPADQPRVQ.SSRTWRPPLVNSRELYRAQRAARC..............................................................
Q7T5C6_CHV1/16-191                  ...layegsrhcg---------------RSVSEDAPPPYSP-PPA.AEAVFVSIDIGESLEAPPPYSP-PVPRGEAGPP---PG---AAAR.ARRAQRRAARRSRRRAGRRAAR-----..GGDYA---LRSPPS------SVGAASPPALPSYSEALRDLPPPYDTVISVDAHDglesRTEASLvhHPQRHERPS.PSRLSRPPRVSSRELYRCRRAA--lv............................................................
Q2QBB9_CHV16/17-191                 ayegsrdlapalp-------------------VGAPPPYSPPPGT.D-ATFVSIDIGDPAEPPPPYS---------PPA-QGAGGRS----.SRRAQRRAARRSRRRAERRERLAARRPpdSGRRAD-----DSAESSASLDDAT-AAPALPTYREALRDLPPSYDTVISVDARDd..lHPQTEA..SPIDPRRGDrPSRPPRPPRVSSRELYRYRQAA--lf............................................................
A0A060Q5A6_9ALPH/45-248             ....thlslppsa------------------STSPPPPYFS--GRiDDTEYTSITLHSPTSPPPAYDPGDQLAQVVGPASRLAAPRPLRPQgGRRPSNRALRRAQRRSERRSQRRARCT..AGGFLQDPVSLPQTPLTAPWCEWGGPIALLPTYSESELDQPPPYTSP-------....------..---------.------------------------qpnsalqatpypqspapraqpvsitisepeetewedqapahferrprissrelnrmrlrgal
UL56_HHV11/1-196                    .............MASEAAQPDAGLWSAGNAFADPPPPYDSLSGR.NEGPFVVIDLDTPTDPPPPYSAGPLLSVPIPPTSSGEGEASERGR.SRQAAQRAARRARRRAERRAQRRSFGP..GGLLA-TPLFLPETRLVAPPDITRDLLSGLPTYAEAMSDHPPTYATVVAVRSTE....QPSGAL..APDDQRRTQ.NSGAWRPPRVNSRELYRAQRAARL..............................................................
#=GC seq_cons                       ....sh......s...............tssssDAPPPYsS.sGs.s-usFVSIDIcoPT-PPPPYSsGs..ss.luPASpGsGttstRuR.SRRAupRAARRARRRAERRApRRuhsP..GGtaApsPLhLPpT.lsAs.sluusssuuLPTYuEAhpDpPPoYsTVluVcup-....pPpuul..uPtDpcRsp.sSRs.RPPRVsSRELYRspRAA................................................................
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