GenomeNet

Database: Pfam
Entry: IF2_N
LinkDB: IF2_N
Original site: IF2_N 
#=GF ID   IF2_N
#=GF AC   PF04760.15
#=GF DE   Translation initiation factor IF-2, N-terminal region
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF AU   Laursen BS;
#=GF AU   Studholme DJ;0000-0002-3010-6637
#=GF SE   DOMO:DM04974;
#=GF GA   25.00 25.00;
#=GF TC   25.00 25.00;
#=GF NC   24.90 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   1764105
#=GF RT   Tandem translation of E. coli initiation factor IF2 beta:
#=GF RT   purification and characterization in vitro of two active forms. 
#=GF RA   Nyengaard NR, Mortensen KK, Lassen SF, Hershey JW,
#=GF RA   Sperling-Petersen HU; 
#=GF RL   Biochem Biophys Res Commun 1991;181:1572-1579.
#=GF RN   [2]
#=GF RM   12600987
#=GF RT   A conserved structural motif at the N-terminus of bacterial
#=GF RT   translation initiation factor IF2. 
#=GF RA   Laursen BS, Mortensen KK, Sperling-Petersen HU, Hoffman DW; 
#=GF RL    0;0:0-0.
#=GF DR   INTERPRO; IPR006847;
#=GF DR   SCOP; 1nd9; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This conserved feature at the N-terminus of bacterial
#=GF CC   translation initiation factor IF2 has recently had its structure
#=GF CC   solved.  It shows structural similarity to the tRNA anticodon
#=GF CC   Stem Contact Fold domains of the methionyl-tRNA and
#=GF CC   glutaminyl-tRNA synthetases, and a similar fold is also found in
#=GF CC   the B5 domain of the phenylalanine-tRNA synthetase.
#=GF SQ   11075
#=GS A0A0C5JAQ4_9RHOO/1-53       AC A0A0C5JAQ4.1
#=GS A0A1M3NED6_9DELT/1-53       AC A0A1M3NED6.1
#=GS A0A178KA21_9GAMM/1-52       AC A0A178KA21.1
#=GS A0A0F3IKM7_9GAMM/1-53       AC A0A0F3IKM7.1
#=GS A0A1H8HM17_9BACI/1-53       AC A0A1H8HM17.1
#=GS A0A0M4MCR5_9ACTN/31-82      AC A0A0M4MCR5.1
#=GS A0A0F6QWG8_9CORY/2-54       AC A0A0F6QWG8.1
#=GS A0A1B1BGZ4_9MICO/3-54       AC A0A1B1BGZ4.1
#=GS A0A1W1ZW25_9DELT/470-521    AC A0A1W1ZW25.1
#=GS A0A1S2I1Q7_9MICO/359-408    AC A0A1S2I1Q7.1
#=GS A0A0U5GNS2_9EURO/417-469    AC A0A0U5GNS2.1
#=GS A0A1H8Z2C7_9GAMM/312-362    AC A0A1H8Z2C7.1
#=GS A0A0N1IXW2_9ACTN/22-71      AC A0A0N1IXW2.1
#=GS A0A109W2T9_9ACTO/1-58       AC A0A109W2T9.1
#=GS IF2_DESPS/1-53              AC Q6AJY4.1
#=GS A0A2A2GYV7_9GAMM/1-52       AC A0A2A2GYV7.1
#=GS A0A1H6ZCJ3_9GAMM/342-388    AC A0A1H6ZCJ3.1
#=GS A0A261DD65_9RICK/261-312    AC A0A261DD65.1
#=GS A0A1G1Y6W1_9BACT/82-133     AC A0A1G1Y6W1.1
#=GS A0A1P9WY51_9BACT/529-580    AC A0A1P9WY51.1
#=GS A0A257FMH8_9BURK/435-486    AC A0A257FMH8.1
#=GS N9Y0X8_9CLOT/1-52           AC N9Y0X8.1
#=GS A0A1F8RIR7_9CHLR/12-63      AC A0A1F8RIR7.1
#=GS A0A1B9EJP0_9ACTN/24-72      AC A0A1B9EJP0.1
#=GS H8G622_9PSEU/105-155        AC H8G622.1
#=GS A0A132NCU7_HYDSH/96-147     AC A0A132NCU7.1
#=GS F8JFL1_HYPSM/368-419        AC F8JFL1.1
#=GS D6S5Q2_9LACO/324-375        AC D6S5Q2.1
#=GS W4QVZ9_BACA3/1-49           AC W4QVZ9.1
#=GS IF2_BORA1/1-53              AC Q2KXY7.1
#=GS IF2_NITMU/300-350           AC Q2Y7W2.1
#=GS A0A1Z1WKC2_9ACTN/24-73      AC A0A1Z1WKC2.1
#=GS A0A0F7PP34_9RHIZ/290-341    AC A0A0F7PP34.1
#=GS A0A1Y0M8P0_9FLAO/381-432    AC A0A1Y0M8P0.1
#=GS B1YI62_EXIS2/2-52           AC B1YI62.1
#=GS A0A1G7VTQ0_9BRAD/357-408    AC A0A1G7VTQ0.1
#=GS R5QVD1_9FIRM/1-53           AC R5QVD1.1
#=GS I3ZKG7_TERRK/1-53           AC I3ZKG7.1
#=GS A0A0Q4SF74_9FLAO/385-436    AC A0A0Q4SF74.1
#=GS A0A1N7GJI3_9ACTN/21-70      AC A0A1N7GJI3.1
#=GS V6S0V2_9FLAO/327-378        AC V6S0V2.1
#=GS A0A0D6N1R9_9PROT/316-367    AC A0A0D6N1R9.1
#=GS D0WR21_9ACTO/1-53           AC D0WR21.1
#=GS IF2_OCEIH/1-53              AC Q8EQU1.1
#=GS A0A1Q4HB01_9MYCO/24-72      AC A0A1Q4HB01.1
#=GS IF2_STRSY/1-53              AC A4VXH3.1
#=GS A0A1H2LVD0_9ACTN/432-481    AC A0A1H2LVD0.1
#=GS A0A254T7C1_9BURK/362-413    AC A0A254T7C1.1
#=GS IF2_CORA7/319-368           AC C3PH19.1
#=GS G8BN33_TETPH/54-106         AC G8BN33.1
#=GS IF2_PSEHT/310-361           AC Q3IJ53.1
#=GS A0A1D4IXH4_STACC/1-53       AC A0A1D4IXH4.1
#=GS A0A1Q8RJT1_9STRE/1-53       AC A0A1Q8RJT1.1
#=GS A0A2H3ERH4_9HELO/512-564    AC A0A2H3ERH4.1
#=GS A0A0F6BPI9_GEOS0/165-216    AC A0A0F6BPI9.1
#=GS A0A0S2FC44_9GAMM/302-353    AC A0A0S2FC44.1
#=GS A0A1F6LHL4_9BACT/83-134     AC A0A1F6LHL4.1
#=GS A0A0W1SDL1_9GAMM/1-52       AC A0A0W1SDL1.1
#=GS D4YV52_9LACO/7-59           AC D4YV52.1
#=GS A0A254NB88_9BURK/1-53       AC A0A254NB88.1
#=GS A0A162CW73_MYCKA/2-54       AC A0A162CW73.1
#=GS A0A0H0ZLB5_9MICC/367-416    AC A0A0H0ZLB5.1
#=GS A0A2D0KTU9_9GAMM/1-52       AC A0A2D0KTU9.1
#=GS A0A1G8YTE4_9ACTN/499-548    AC A0A1G8YTE4.1
#=GS IF2_MICLC/338-387           AC C5C9T1.1
#=GS A0A0A7JJA1_9PSED/269-320    AC A0A0A7JJA1.1
#=GS A0A1H9QGR2_9BACI/142-193    AC A0A1H9QGR2.1
#=GS F7KBA9_9FIRM/477-527        AC F7KBA9.1
#=GS A0A073IMG1_9RHOB/244-295    AC A0A073IMG1.1
#=GS A0A231P772_9ACTN/342-391    AC A0A231P772.1
#=GS E8W7F7_STRFA/24-72          AC E8W7F7.1
#=GS A0A1L7D2H0_9CORY/2-49       AC A0A1L7D2H0.1
#=GS K9YSE8_DACSA/463-515        AC K9YSE8.1
#=GS A0A1H3NNV7_9CLOT/1-50       AC A0A1H3NNV7.1
#=GS U2D9A1_9FIRM/120-170        AC U2D9A1.1
#=GS A0A1I7K9N9_9GAMM/266-317    AC A0A1I7K9N9.1
#=GS A0A0J1GM05_9GAMM/1-52       AC A0A0J1GM05.1
#=GS A0A1G5HVK1_9FIRM/1-49       AC A0A1G5HVK1.1
#=GS A0A1X0JHU7_9MYCO/328-377    AC A0A1X0JHU7.1
#=GS A0A291P2R2_9GAMM/1-53       AC A0A291P2R2.1
#=GS A0A1B9B0L2_9BACI/1-53       AC A0A1B9B0L2.1
#=GS H1XXM9_9BACT/349-400        AC H1XXM9.1
#=GS A0A1I3NV28_9BACL/22-72      AC A0A1I3NV28.1
#=GS A0A0F5ANT2_9GAMM/328-379    AC A0A0F5ANT2.1
#=GS R6QY68_9CLOT/219-270        AC R6QY68.1
#=GS A0A1I6SNM1_9BACL/7-55       AC A0A1I6SNM1.1
#=GS A0A2A9CH35_9BACI/1-52       AC A0A2A9CH35.1
#=GS A0A1F5S2K3_9BACT/84-135     AC A0A1F5S2K3.1
#=GS A0A1V8ZX16_9PSEU/27-79      AC A0A1V8ZX16.1
#=GS A0A1V2YJF7_9FIRM/13-63      AC A0A1V2YJF7.1
#=GS A0A1H1FG08_9ACTN/1-52       AC A0A1H1FG08.1
#=GS M2UE92_COCH5/411-463        AC M2UE92.1
#=GS A0A0C2VUT0_9BACL/1-53       AC A0A0C2VUT0.1
#=GS A0A1I4M578_9PROT/1-52       AC A0A1I4M578.1
#=GS A0A1H9Q9H8_9BACI/151-201    AC A0A1H9Q9H8.1
#=GS A0A2G4I5Z9_9BACT/2-52       AC A0A2G4I5Z9.1
#=GS R6LUA4_9FIRM/79-130         AC R6LUA4.1
#=GS U7UCT7_9FIRM/273-324        AC U7UCT7.1
#=GS A0A0A0C9P1_9CELL/87-135     AC A0A0A0C9P1.1
#=GS W0AL31_9SPHN/294-345        AC W0AL31.1
#=GS K1M1Y8_9LACT/1-51           AC K1M1Y8.1
#=GS A0A0G1R8N8_9BACT/83-134     AC A0A0G1R8N8.1
#=GS J2P8Z8_9SPHN/352-403        AC J2P8Z8.1
#=GS A0A0A7JJA1_9PSED/1-53       AC A0A0A7JJA1.1
#=GS A0A017RUT5_9CLOT/1-53       AC A0A017RUT5.1
#=GS A0A1H9HW65_9FIRM/360-411    AC A0A1H9HW65.1
#=GS W6MSX3_9ASCO/209-261        AC W6MSX3.1
#=GS R5EIV2_9GAMM/267-318        AC R5EIV2.1
#=GS R6MSD2_9FIRM/1-53           AC R6MSD2.1
#=GS A0A062Y2A2_9BACT/330-381    AC A0A062Y2A2.1
#=GS Q4ECK1_9RICK/197-249        AC Q4ECK1.1
#=GS B9NTE9_9RHOB/245-296        AC B9NTE9.1
#=GS A0A0G4JR98_9GAMM/325-376    AC A0A0G4JR98.1
#=GS Q4C0K8_CROWT/6-56           AC Q4C0K8.1
#=GS A0A0V2FEN2_CAUVI/454-505    AC A0A0V2FEN2.1
#=GS IF2_THET8/1-52              AC P48515.2
#=GS IF2_THET8/1-52              DR PDB; 4KJZ D; 4-52;
#=GS IF2_THET8/1-52              DR PDB; 4B44 A; 2-52;
#=GS IF2_THET8/1-52              DR PDB; 4B47 A; 2-52;
#=GS IF2_THET8/1-52              DR PDB; 3J4J A; 1-52;
#=GS IF2_THET8/1-52              DR PDB; 4B43 A; 1-52;
#=GS IF2_THET8/1-52              DR PDB; 4B3X A; 1-52;
#=GS IF2_THET8/1-52              DR PDB; 4KJZ B; 3-52;
#=GS IF2_THET8/1-52              DR PDB; 4KJZ C; 3-52;
#=GS IF2_THET8/1-52              DR PDB; 4B48 A; 1-52;
#=GS IF2_THET8/1-52              DR PDB; 4KJZ A; 3-52;
#=GS A0A1S6QKI3_9LACO/1-53       AC A0A1S6QKI3.1
#=GS H8GE64_9PSEU/27-79          AC H8GE64.1
#=GS E8M0Q2_9VIBR/318-369        AC E8M0Q2.1
#=GS A0A1G5GMP1_9FIRM/422-472    AC A0A1G5GMP1.1
#=GS A0A1H0KQW3_9RALS/1-53       AC A0A1H0KQW3.1
#=GS A0A1F8KJ78_9CHLR/12-63      AC A0A1F8KJ78.1
#=GS A0A1M6EY06_9FIRM/2-52       AC A0A1M6EY06.1
#=GS A0A0U3DPT2_9LACT/208-259    AC A0A0U3DPT2.1
#=GS I2GE51_9BACT/585-636        AC I2GE51.1
#=GS A0A2C9XQ18_9ENTE/1-53       AC A0A2C9XQ18.1
#=GS A0A1Z5HXP2_9THEO/159-210    AC A0A1Z5HXP2.1
#=GS A0A1V6Q481_9EURO/478-530    AC A0A1V6Q481.1
#=GS A0A286E175_9ACTN/409-458    AC A0A286E175.1
#=GS A0A1A3MXG5_MYCAS/2-54       AC A0A1A3MXG5.1
#=GS A0A1Y4MAL2_9FIRM/199-250    AC A0A1Y4MAL2.1
#=GS R4WR77_9BURK/418-469        AC R4WR77.1
#=GS A0A1J5MNW1_9GAMM/311-362    AC A0A1J5MNW1.1
#=GS A0A1G6ANU1_EUBOX/334-384    AC A0A1G6ANU1.1
#=GS D5X0N4_THIK1/395-446        AC D5X0N4.1
#=GS A0A1P8YL00_9NOCA/24-72      AC A0A1P8YL00.1
#=GS R4PVX1_9BACT/12-63          AC R4PVX1.1
#=GS A0A1M5G6C7_9BACT/410-461    AC A0A1M5G6C7.1
#=GS A0A099VYJ9_9HELI/1-52       AC A0A099VYJ9.1
#=GS A0A268TWR8_9HELI/1-53       AC A0A268TWR8.1
#=GS N2BJ63_9ACTN/307-358        AC N2BJ63.1
#=GS A0A1H7K2L4_9BURK/396-447    AC A0A1H7K2L4.1
#=GS A0A1G0XG78_9BACT/6-58       AC A0A1G0XG78.1
#=GS A0A1I7MHS2_9MICC/346-394    AC A0A1I7MHS2.1
#=GS A0A0R2M4D3_9LACO/300-351    AC A0A0R2M4D3.1
#=GS U7PEK4_STASI/136-186        AC U7PEK4.1
#=GS A0A1I6HV16_9ALTE/279-330    AC A0A1I6HV16.1
#=GS A0A0B5IZH0_RAOOR/319-370    AC A0A0B5IZH0.1
#=GS D4H7W9_DENA2/486-537        AC D4H7W9.1
#=GS A0A0L8ATJ5_9BURK/1-53       AC A0A0L8ATJ5.1
#=GS A0A0L0KP79_9ACTN/24-73      AC A0A0L0KP79.1
#=GS D0LZ90_HALO1/480-532        AC D0LZ90.1
#=GS A0A1M7PHU5_9BACI/1-53       AC A0A1M7PHU5.1
#=GS G9WIE7_9LACT/257-306        AC G9WIE7.1
#=GS IF2_SHEPC/302-353           AC A4Y9C0.1
#=GS A0A0M2UWA9_9BACT/1-54       AC A0A0M2UWA9.1
#=GS A0A1M6KH43_MALRU/333-384    AC A0A1M6KH43.1
#=GS Q2CJN5_OCEGH/230-281        AC Q2CJN5.1
#=GS A0A0P6ZWB1_9SPHN/284-335    AC A0A0P6ZWB1.1
#=GS A0A1C5BJT5_9ACTN/24-72      AC A0A1C5BJT5.1
#=GS A0A1M3HGE7_9SPHI/428-479    AC A0A1M3HGE7.1
#=GS E9T6X5_RHOHA/19-69          AC E9T6X5.1
#=GS IF2_PSEMY/1-53              AC A4XYE0.1
#=GS F6AE34_PSEF1/1-53           AC F6AE34.1
#=GS W7DKG6_9PROT/378-429        AC W7DKG6.1
#=GS A4EH14_9RHOB/248-299        AC A4EH14.1
#=GS C2D4E7_LACBR/1-49           AC C2D4E7.1
#=GS A0A023DBA5_9BACI/157-208    AC A0A023DBA5.1
#=GS A0A1E4SIZ8_9ASCO/151-203    AC A0A1E4SIZ8.1
#=GS L0NKZ2_9RHIZ/311-362        AC L0NKZ2.1
#=GS C7MQV1_SACVD/2-54           AC C7MQV1.1
#=GS R6M7J9_9FIRM/2-67           AC R6M7J9.1
#=GS A0A1G7EXT3_9BACL/7-57       AC A0A1G7EXT3.1
#=GS I7L4X2_9LACO/7-58           AC I7L4X2.1
#=GS A0A1W9Z866_9MYCO/210-258    AC A0A1W9Z866.1
#=GS A0A1A9RWY6_9NEIS/2-52       AC A0A1A9RWY6.1
#=GS A0A1W1XD04_9CLOT/118-169    AC A0A1W1XD04.1
#=GS A0A0B4XSI4_9GAMM/330-381    AC A0A0B4XSI4.1
#=GS A0A078LY16_9PSED/252-303    AC A0A078LY16.1
#=GS A0A1G5B9X0_9FIRM/313-363    AC A0A1G5B9X0.1
#=GS G0V7K4_NAUCC/66-117         AC G0V7K4.1
#=GS A0A1Z4Q3E7_9CYAN/3-54       AC A0A1Z4Q3E7.1
#=GS A0A085G1S9_9ENTR/317-368    AC A0A085G1S9.1
#=GS G4CUB3_9ACTN/378-427        AC G4CUB3.1
#=GS A0A1G1KYW8_9BACT/1-45       AC A0A1G1KYW8.1
#=GS IF2_WOLSU/360-411           AC Q7M7X5.1
#=GS A0A1H7ITB9_9SPHN/374-425    AC A0A1H7ITB9.1
#=GS G2PJT3_MURRD/337-388        AC G2PJT3.1
#=GS A0A1X3D657_9NEIS/352-403    AC A0A1X3D657.1
#=GS A0A1H6QPU3_9FIRM/305-355    AC A0A1H6QPU3.1
#=GS A0A1G7D5N6_9PROT/298-349    AC A0A1G7D5N6.1
#=GS A0A1M6I514_9CLOT/1-52       AC A0A1M6I514.1
#=GS W6K461_9MICO/24-73          AC W6K461.1
#=GS A0A0N0UV55_9LACO/168-219    AC A0A0N0UV55.1
#=GS A0A0R1P333_9LACO/1-49       AC A0A0R1P333.1
#=GS A0A0C1DH07_9SPHI/446-497    AC A0A0C1DH07.1
#=GS A0A2G2CNW8_9HELI/2-53       AC A0A2G2CNW8.1
#=GS A0A1S8CGV7_9GAMM/318-369    AC A0A1S8CGV7.1
#=GS A0A0A2MIR2_9FLAO/396-447    AC A0A0A2MIR2.1
#=GS A0A1V9V8T6_9PROT/312-363    AC A0A1V9V8T6.1
#=GS IF2_COXBU/225-276           AC Q83BS1.1
#=GS A0A1S6HV43_9GAMM/314-365    AC A0A1S6HV43.1
#=GS G5GRW2_9FIRM/266-317        AC G5GRW2.1
#=GS A0A124FQA2_9BACT/1-52       AC A0A124FQA2.1
#=GS A0A0D0LE79_9NOCA/149-199    AC A0A0D0LE79.1
#=GS A0A1X3D657_9NEIS/1-53       AC A0A1X3D657.1
#=GS A0A1I3YUC4_9CELL/1-52       AC A0A1I3YUC4.1
#=GS A0A1V3N5B0_9SPHI/471-522    AC A0A1V3N5B0.1
#=GS I7K7M2_9CLOT/1-53           AC I7K7M2.1
#=GS A0A0D5NRE7_9BACL/313-363    AC A0A0D5NRE7.1
#=GS IF2_SHEWM/1-51              AC B1KRR0.1
#=GS A0A1T1BUL1_9FLAO/384-435    AC A0A1T1BUL1.1
#=GS G1XWR1_9PROT/50-101         AC G1XWR1.1
#=GS A0A099JH52_9MICO/370-419    AC A0A099JH52.1
#=GS A0A243QQB9_9ACTN/1-53       AC A0A243QQB9.1
#=GS C1HAP7_PARBA/430-482        AC C1HAP7.2
#=GS A0A1V9UM53_9PSED/1-52       AC A0A1V9UM53.1
#=GS A0A165L1W7_9BURK/1-53       AC A0A165L1W7.1
#=GS A0A085LF84_9MICO/358-405    AC A0A085LF84.1
#=GS A0A1Q8S132_9PEZI/440-492    AC A0A1Q8S132.1
#=GS H3NEZ5_9LACT/1-53           AC H3NEZ5.1
#=GS A0A081N379_9GAMM/303-354    AC A0A081N379.1
#=GS A0A0R2HNG1_CARDV/227-278    AC A0A0R2HNG1.1
#=GS A0A0U5MDL6_9PROT/295-346    AC A0A0U5MDL6.1
#=GS E0QSP5_9ACTO/329-379        AC E0QSP5.1
#=GS A0A1S6XFK3_9RHIZ/272-323    AC A0A1S6XFK3.1
#=GS R7GVI4_9FIRM/331-382        AC R7GVI4.1
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