GenomeNet

Database: Pfam
Entry: IL1_propep
LinkDB: IL1_propep
Original site: IL1_propep 
#=GF ID   IL1_propep
#=GF AC   PF02394.16
#=GF DE   Interleukin-1 propeptide
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_1500 (release 5.2)
#=GF GA   21.30 21.30;
#=GF TC   21.60 21.50;
#=GF NC   21.00 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR003502;
#=GF DR   PROSITE; PDOC00226;
#=GF DR   SCOP; 2mib; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The Interleukin-1 cytokines are translated as precursor
#=GF CC   proteins.  The N terminal approx. 115 amino acids form a
#=GF CC   propeptide that is cleaved off to release the active
#=GF CC   interleukin-1.
#=GF SQ   149
#=GS A0A0Q3X8K9_AMAAE/3-94    AC A0A0Q3X8K9.1
#=GS G1PEV6_MYOLU/1-104       AC G1PEV6.1
#=GS M4WG34_SHEEP/1-101       AC M4WG34.2
#=GS L5KV65_PTEAL/1-109       AC L5KV65.1
#=GS I3M045_ICTTR/1-109       AC I3M045.1
#=GS Q5BKB0_RAT/1-102         AC Q5BKB0.1
#=GS A0A287BHV2_PIG/1-105     AC A0A287BHV2.1
#=GS IL1A_RABIT/1-109         AC P04822.1
#=GS IL1B_MOUSE/1-102         AC P10749.1
#=GS G3W2K5_SARHA/1-98        AC G3W2K5.1
#=GS S9X3D6_CAMFR/1-102       AC S9X3D6.1
#=GS A0A091D913_FUKDA/1-111   AC A0A091D913.1
#=GS F7C3T8_HORSE/1-109       AC F7C3T8.1
#=GS Q2VCE2_CANLF/1-101       AC Q2VCE2.1
#=GS IL1B_BOVIN/1-101         AC P09428.2
#=GS A0A1U7Q9G0_MESAU/1-102   AC A0A1U7Q9G0.1
#=GS IL1A_CANLF/1-105         AC O46612.1
#=GS L9JMH4_TUPCH/1-109       AC L9JMH4.1
#=GS A0A0M3KL74_CHLSB/1-72    AC A0A0M3KL74.1
#=GS A0A2K5NFE1_CERAT/16-86   AC A0A2K5NFE1.1
#=GS A0A287B6X4_PIG/1-101     AC A0A287B6X4.1
#=GS IL1B_HORSE/1-103         AC Q28386.1
#=GS A0A2K5LYJ6_CERAT/1-93    AC A0A2K5LYJ6.1
#=GS G3W4G1_SARHA/1-105       AC G3W4G1.1
#=GS F7G8J2_MACMU/1-103       AC F7G8J2.1
#=GS A0A1S2ZW37_ERIEU/1-103   AC A0A1S2ZW37.1
#=GS A0A1D5P4U4_CHICK/28-109  AC A0A1D5P4U4.1
#=GS A0A286ZMX3_PIG/1-100     AC A0A286ZMX3.1
#=GS IL1A_MOUSE/1-111         AC P01582.1
#=GS A0A1U7SH35_ALLSI/1-89    AC A0A1U7SH35.1
#=GS IL1A_HORSE/1-109         AC Q28385.1
#=GS G5B005_HETGA/1-111       AC G5B005.1
#=GS A0A1S3FGQ2_DIPOR/1-111   AC A0A1S3FGQ2.1
#=GS IL1B_CANLF/1-102         AC Q28292.2
#=GS A0A0A0MPZ0_FELCA/1-103   AC A0A0A0MPZ0.1
#=GS R7VSW8_COLLI/1-96        AC R7VSW8.1
#=GS IL1A_MACMU/1-109         AC P48089.1
#=GS H9H271_MELGA/44-121      AC H9H271.1
#=GS H0YYU7_TAEGU/1-96        AC H0YYU7.1
#=GS IL1A_PIG/1-109           AC P18430.1
#=GS A0A1U7Q4M0_MESAU/1-111   AC A0A1U7Q4M0.1
#=GS A0A1U7TBU6_TARSY/1-103   AC A0A1U7TBU6.1
#=GS G3QLV0_GORGO/1-109       AC G3QLV0.1
#=GS F1MAF9_RAT/1-102         AC F1MAF9.3
#=GS A0A218UCE5_9PASE/1-96    AC A0A218UCE5.1
#=GS IL1B_PIG/1-102           AC P26889.1
#=GS IL1A_RAT/1-111           AC P16598.1
#=GS A0A0A0MPZ7_FELCA/1-100   AC A0A0A0MPZ7.2
#=GS H2QIK6_PANTR/1-103       AC H2QIK6.1
#=GS S9X0V8_CAMFR/4-111       AC S9X0V8.1
#=GS F1LQB1_RAT/1-108         AC F1LQB1.3
#=GS A3DTN5_MELGA/1-94        AC A3DTN5.1
#=GS IL1B_RAT/1-102           AC Q63264.1
#=GS F6RH14_CALJA/1-103       AC F6RH14.1
#=GS A0A2C9F3A1_PIG/1-101     AC A0A2C9F3A1.1
#=GS F6X1Q9_XENTR/3-109       AC F6X1Q9.1
#=GS O73909_CHICK/1-94        AC O73909.1
#=GS L5KTV2_PTEAL/1-104       AC L5KTV2.1
#=GS A0A287BRB4_PIG/1-105     AC A0A287BRB4.1
#=GS A0A2K5K1S5_COLAP/1-109   AC A0A2K5K1S5.1
#=GS L9JLW9_TUPCH/1-103       AC L9JLW9.1
#=GS U3JBA2_FICAL/1-96        AC U3JBA2.1
#=GS A0A1S3FFR2_DIPOR/1-102   AC A0A1S3FFR2.1
#=GS A0A1U7T5G9_TARSY/1-110   AC A0A1U7T5G9.1
#=GS A0A287AFR7_PIG/1-41      AC A0A287AFR7.1
#=GS A0A2I3HN27_NOMLE/1-103   AC A0A2I3HN27.1
#=GS IL1A_FELCA/1-109         AC O46613.1
#=GS IL1A_SHEEP/1-109         AC Q28579.1
#=GS IL1A_CERAT/1-109         AC P46647.1
#=GS G1LW58_AILME/1-105       AC G1LW58.1
#=GS G1TXR4_RABIT/16-96       AC G1TXR4.1
#=GS IL1B_FELCA/1-103         AC P41687.1
#=GS A0A1S2ZW61_ERIEU/1-109   AC A0A1S2ZW61.1
#=GS B7ZSG9_XENLA/1-104       AC B7ZSG9.1
#=GS IL1B_RABIT/1-103         AC P14628.1
#=GS A0A1V4KH82_PATFA/1-96    AC A0A1V4KH82.1
#=GS B1AB80_HORSE/1-103       AC B1AB80.1
#=GS F6SEZ4_MONDO/6-96        AC F6SEZ4.1
#=GS S7Q8Z4_MYOBR/1-109       AC S7Q8Z4.1
#=GS H2UVE2_TAKRU/1-76        AC H2UVE2.1
#=GS Q712K7_ORNAN/1-117       AC Q712K7.1
#=GS A0A093NUK4_PYGAD/1-96    AC A0A093NUK4.1
#=GS A0A2K5NF39_CERAT/1-109   AC A0A2K5NF39.1
#=GS F6SXC0_MONDO/1-114       AC F6SXC0.1
#=GS H2QIK5_PANTR/1-109       AC H2QIK5.1
#=GS A0A151MMR4_ALLMI/1-92    AC A0A151MMR4.1
#=GS A0A1A6HM55_NEOLE/1-102   AC A0A1A6HM55.1
#=GS C9JWV2_HUMAN/1-103       AC C9JWV2.1
#=GS IL1A_HUMAN/1-109         AC P01583.1
#=GS M7AWZ8_CHEMY/58-162      AC M7AWZ8.1
#=GS A0A287B6V6_PIG/35-106    AC A0A287B6V6.1
#=GS A0A096NEW1_PAPAN/1-103   AC A0A096NEW1.1
#=GS IL1B_CAVPO/1-102         AC Q9WVG1.1
#=GS A0A0G2K003_RAT/1-109     AC A0A0G2K003.1
#=GS A0A1A6HKM2_NEOLE/2-87    AC A0A1A6HKM2.1
#=GS A0A091D3R2_FUKDA/1-101   AC A0A091D3R2.1
#=GS A0A140T838_BOVIN/1-101   AC A0A140T838.1
#=GS IL1B_HUMAN/1-103         AC P01584.2
#=GS G1LW44_AILME/1-104       AC G1LW44.1
#=GS IL1A_CAVPO/1-107         AC Q60480.1
#=GS IL1B_MUSPF/1-105         AC A4UYK8.1
#=GS A0A087QNQ2_APTFO/1-96    AC A0A087QNQ2.1
#=GS M3YEA4_MUSPF/1-112       AC M3YEA4.1
#=GS IL1A_BOVIN/1-109         AC P08831.1
#=GS G3QU53_GORGO/1-103       AC G3QU53.1
#=GS A0A226P217_COLVI/1-94    AC A0A226P217.1
#=GS G3SN89_LOXAF/1-109       AC G3SN89.1
#=GS A0A2K5LYI4_CERAT/1-103   AC A0A2K5LYI4.1
#=GS IL1B_SHEEP/1-101         AC P21621.2
#=GS A0A2I2UR90_FELCA/1-109   AC A0A2I2UR90.1
#=GS U3JBA1_FICAL/1-95        AC U3JBA1.1
#=GS A0A096NPG5_PAPAN/1-109   AC A0A096NPG5.1
#=GS A0A2K5JR15_COLAP/1-103   AC A0A2K5JR15.1
#=GS H0W1R8_CAVPO/1-114       AC H0W1R8.2
#=GS A0A2I3N9K4_PAPAN/1-93    AC A0A2I3N9K4.1
#=GS A0A2I3LTT5_PAPAN/1-101   AC A0A2I3LTT5.1
#=GS V8PGF3_OPHHA/156-223     AC V8PGF3.1
#=GS G1NSN5_MYOLU/1-109       AC G1NSN5.1
#=GS A0A2G9RS62_LITCT/1-103   AC A0A2G9RS62.1
#=GS A0A287AKL5_PIG/2-101     AC A0A287AKL5.1
#=GS G3I1B0_CRIGR/1-72        AC G3I1B0.1
#=GS H2P5G1_PONAB/1-111       AC H2P5G1.1
#=GS G3STJ8_LOXAF/1-100       AC G3STJ8.1
#=GS F6VT34_CALJA/1-109       AC F6VT34.1
#=GS A0A140T8E9_CANLF/1-105   AC A0A140T8E9.1
#=GS F7G8K0_MACMU/1-62        AC F7G8K0.2
#=GS S7NJ59_MYOBR/1-104       AC S7NJ59.1
#=GS G1QMS9_NOMLE/1-109       AC G1QMS9.2
#=GS A0A2G9RQ98_LITCT/32-134  AC A0A2G9RQ98.1
#=GS A0A287AFR7_PIG/35-78     AC A0A287AFR7.1
#=GS H2P5G2_PONAB/1-103       AC H2P5G2.1
#=GS I3M051_ICTTR/1-89        AC I3M051.2
#=GS C9JVK0_HUMAN/1-103       AC C9JVK0.1
#=GS A0T125_CANLF/1-95        AC A0T125.1
#=GS G7PMZ6_MACFA/1-109       AC G7PMZ6.1
#=GS A0A0D9RW29_CHLSB/1-62    AC A0A0D9RW29.1
#=GS H0WRY2_OTOGA/1-104       AC H0WRY2.1
#=GS G7PMZ7_MACFA/1-103       AC G7PMZ7.1
#=GS F1SUB9_PIG/1-101         AC F1SUB9.2
#=GS IL1B_MACMU/1-103         AC P48090.1
#=GS C9JSC2_HUMAN/1-103       AC C9JSC2.1
#=GS A0A287A4B5_PIG/3-100     AC A0A287A4B5.1
#=GS W5QI89_SHEEP/42-150      AC W5QI89.1
#=GS H2UVE3_TAKRU/1-76        AC H2UVE3.1
#=GS G5B006_HETGA/35-136      AC G5B006.1
#=GS IL1B_CERAT/1-103         AC P46648.1
#=GS L5LRV7_MYODS/1-109       AC L5LRV7.1
#=GS H0WRY4_OTOGA/1-103       AC H0WRY4.1
#=GS F7CCI7_HORSE/1-103       AC F7CCI7.1
A0A0Q3X8K9_AMAAE/3-94               ................................MAFVPDL--.......DVLE....-.-.......SSSPNEETFYGPDC.LCLQkKPRLDL.............EVAS-----..PGVDIQVTVTKGHPAR..TFHQA.....AVL.VAAV....TKPAH--..----KEFADSDLGGFLDDIFE----pv.................................................
G1PEV6_MYOLU/1-104                  ................................MAAVPELAN.......EVMA....Y.Y.......SDDENGLFFEADGP.QQTK.CSFQDL.............DLSP----L..GDGSIQLKVSQQLYNS..SFRRA.....VSV.VIAV....EKLRKVH..MVCPQDFQDDDLRSLFFFIFKEESI...................................................
M4WG34_SHEEP/1-101                  ................................MATVPEPIN.......EVMA....Y.Y.......-SDANELLFEVDGP.KQMK.SCTQHL.............DLGS----M..GDGNIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLRSR-..-AYEHVFRDDDLRSILSFIFEEEPV...................................................
L5KV65_PTEAL/1-109                  ................................MAKVPDVFE.......DLKN....C.Y.......--SENEEYSSDADQ.LSLNqKSFYDT.............SYDTLHEDH..GGKLRSLGTSEASKMSqlTFKES.....VVV.LAAD...gKVLKKRR..LSFDQFITDEDLEAIANDT-KEEPI...................................................
I3M045_ICTTR/1-109                  ................................MAKVPDLFE.......DLKD....C.Y.......--SEDEDYNSTMDH.LSLHqKSFYTT.............SYHSLGETC..VDKLMSRSTSETSKTSklTFKES.....LVL.VSAN...gKTLKKRR..LSFHQPISDDDLEAIAYDL-EEEPI...................................................
Q5BKB0_RAT/1-102                    ................................MATVPELNC.......EIAA....F.-.......DSEENDLFFEADRP.QKIK.DCFQAL.............DLG-----C..PDESIQLQISQQHLDK..SFRKA.....VSL.IVAV....EKLWQLP..MSCPWSFQDEDPSTFFSFIFEEEPV...................................................
A0A287BHV2_PIG/1-105                ................................MATVPEPAK.......EVMQalcfY.Y.......SDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
IL1A_RABIT/1-109                    ................................MAKVPDLFE.......DLKN....C.F.......--SENEEYSSAIDH.LSLNqKSFYDA.............SYEPLHEDC..MNKVVSLSTSETSVSPnlTFQEN.....VVA.VTAS...gKILKKRR..LSLNQPITDVDLETNVSDP-EEGII...................................................
IL1B_MOUSE/1-102                    ................................MATVPELNC.......EMPP....F.-.......DSDENDLFFEVDGP.QKMK.GCFQTF.............DLG-----C..PDESIQLQISQQHINK..SFRQA.....VSL.IVAV....EKLWQLP..VSFPWTFQDEDMSTFFSFIFEEEPI...................................................
G3W2K5_SARHA/1-98                   ................................MARVPDIYE.......DLHL....Q.Y.......--SDNEEFISDTHH.VSSSqDSFYTN.............SSPYQEESC..TKLEISEKIHQLNS--..--QDC.....VDApVVKK....KKEKKKQ..ISESHPITS----------------nyvfnvgsnl.........................................
S9X3D6_CAMFR/1-102                  ................................MAAVPEPAS.......EMMA....Y.Y.......SDNDNDLLFEADGP.KQMK.CCVQPL.............DLGS----L..GDEGIKLQISHQLYNK..SFRQV.....VSV.IVAM....EKLSK--..CPYSQYFQDDDLRNIFSLIFEEEPV...................................................
A0A091D913_FUKDA/1-111              ................................MAEVPNLFE.......DLKS....C.Y.......--SENEEYASAIDR.FSLNqKSFYDT.............SYGPLDENC..MNKSVSLSTLQTSEVSelSFKEN.....LVV.VSTSa.hrKVLKKRR..LSLNQTITNEDLEAIINGP-EEEII...................................................
F7C3T8_HORSE/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLTqKSFYDA.............SYDPLPEDC..MDTFMSLSTSETSKTSklNFKES.....VVL.VAAN...gKTLKKRR..LSLNQFITNDDLEAIANDP-EEGII...................................................
Q2VCE2_CANLF/1-101                  ................................MAAVPELTS.......EMMA....Y.S.......SNNENDLFFEADGP.GNVK.CCCQDL.............NHSS----L..VDEGIQLQVSHQLCNK..SLRHF.....VSV.IVAL....EKLKK--..-PCPQVLQEDDLKSIFCYIFEEEPI...................................................
IL1B_BOVIN/1-101                    ................................MATVPEPIN.......EMMA....Y.Y.......-SDENELLFEADDP.KQMK.SCIQHL.............DLGS----M..GDGNIQLQISHQFYNK..SFRQV.....VSV.IVAM....EKLRNS-..-AYAHVFHDDDLRSILSFIFEEEPV...................................................
A0A1U7Q9G0_MESAU/1-102              ................................MATVPELDS.......EMIA....F.H.......-SDENDLFFEVDGL.QKMK.SCFQSL.............DLSY-----..PDESIQLQISKQDLNK..SFRQV.....VSV.IVAV....EKLWNTP..VPCPWTFQDEDLRTFFSFIFEEEPI...................................................
IL1A_CANLF/1-105                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLNqKSFYDM.............SCDPLHEDC..M----SLSTSEISKTSqlTFKEN.....VVV.VAAN...gKILKKRR..LSLSQFITDDDLEGIANDT--EEVIm..................................................
L9JMH4_TUPCH/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENAEYSSSIEH.LSLNqKSFYDS.............SYDPLQEDC..MGQFMTLNTSETSKIStlTFKES.....VVV.TVNG....KILKKRR..LSFSQPITDEDLKVIASDP-VEE--lvv................................................
A0A0M3KL74_CHLSB/1-72               ................................---------.......----....-.-.......--------------.--MK.CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLIPFIFEEEPI...................................................
A0A2K5NFE1_CERAT/16-86              ................................---------.......----....-.-.......--------------.----.------.............SYGPLHESC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSIADDNLEAIANDS-EEEII...................................................
A0A287B6X4_PIG/1-101                ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
IL1B_HORSE/1-103                    ................................MAAVPD-TS.......DMMT....Y.C.......SGNENDLFFEEDGP.KQMK.GSFQDL.............DLSS----M..GDGGIQLQFSHHLYNK..TFKHA.....MSI.IVAV....EKLKKIP..VPCSQAFQDDDLRSLFSVIFEEEPI...................................................
A0A2K5LYJ6_CERAT/1-93               ................................MAEVPELAS.......EMMA....Y.Y.......---------RSVGT.--LRqCSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLIPFIFEEEPV...................................................
G3W4G1_SARHA/1-105                  ................................MAMVPEITC.......EEMD....F.Y.......RDNEH-QFYESDGP.NQKK.GNLQCL.............DLCPKESLL..VEDDIQLKFTAQPH--..QFYRT.....VVV.VVAI....EKMKHLN..KICSQFFQDNDLMNIFTTIFQEEPI...................................................
F7G8J2_MACMU/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLRKML..VPCPQIFQDNDLSTLIPFIFEEEPV...................................................
A0A1S2ZW37_ERIEU/1-103              ................................MAAVPELAS.......EM-V....Y.Y.......SGNENDMLFEVDGP.KQMQ.CCFQDL.............DLSS----Q..GDDNIQLQISHQLYKK..KFRQV.....VSI.IVTV....EKLRHML..VPDSQFSQNDDLKSLFHIIFEEEPI...................................................
A0A1D5P4U4_CHICK/28-109             ..........pslseetfygpsclclqkkprl---------.......----....-.-.......--------------.----.------.............-----DSEH..TTVDVQVTVRKGRGAR..SFRRA.....AVL.VVAM....TKLLRR-..-PRSRDFADSDLSALLEEVFE----pv.................................................
A0A286ZMX3_PIG/1-100                ................................MATVPEPAK.......EVMN....N.G.......-DNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
IL1A_MOUSE/1-111                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSAIDH.LSLNqKSFYDA.............SYGSLHETC..TDQFVSLRTSETSKMSnfTFKES.....RVT.VSATssngKILKKRR..LSFSETFTEDDLQSITHDL-EET--i..................................................
A0A1U7SH35_ALLSI/1-89               ................................MAEVPDFLA.......DQME....T.C.......SMSEE-CFYEADYH.STVKgY--SAA.............PLSP-EESG..CGLNVQLQFTEPKTHR..GFRTT.....VVL.VGAV....EKMRRMP..Q------------------------spqlfkpv...........................................
IL1A_HORSE/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLTqKSFYDA.............SYDPLPEDC..MDTFMSLSTSETSKTSklNFKES.....VVL.VAAN...gKTLKKRR..LSLNQFITNDDLEAIANDP-EEGII...................................................
G5B005_HETGA/1-111                  ................................MAEIPNLFE.......DLKS....C.Y.......--SENEEYASAIDH.LSLNqKSFYDT.............SYGPLDKNC..MNTSMSLRTLETSEASelTFKKN.....LVV.VSTSa.hgTVLKKRW..LSLNQTITNEDLDAIANDP-EEEII...................................................
A0A1S3FGQ2_DIPOR/1-111              ................................MAKVPDLFE.......DLKN....C.Y.......--SEGEEYSSAVDY.VSLNqKSFYEA.............TYQPLNENC..MDKLMSQSTSETSKTSklTLNDG.....LVV.VAKSs.ngKILKKRL..LSLNQTLTDDDLEAINNDE-KEEII...................................................
IL1B_CANLF/1-102                    ................................MAAVPELTS.......EMMA....Y.S.......SNNENDLFFEADGPgNDVK.CCCQDL.............NHSS----L..VDEGIQLQVSHQLCNK..SLRHF.....VSV.IVAL....EKLKK--..-PCPQVLQEDDLKSIFCYIFEEEPI...................................................
A0A0A0MPZ0_FELCA/1-103              ................................MAAVPELTS.......EMMA....Y.Y.......-SDENDLFFEADGP.EKMK.GSLQNL.............SHSF----L..GDEGIQLQISHQPDNK..SLRHA.....VSV.IVAM....EKLKKIS..FPCSQPLQDEDLKSLFCCIFEEEPI...................................................
R7VSW8_COLLI/1-96                   ................................MAFVPDLDT.......--LE....-.-.......SSSLNEETFYGPNC.LCLQkKPRLDL.............EAT-----S..PGVGIQVMATKGHPTR..TFRRA.....AVL.MVAI....SKLLKR-..-PAHKDFADSDLGDFLDDIFE----pv.................................................
IL1A_MACMU/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSITDNNLEAIANDS-EEEII...................................................
H9H271_MELGA/44-121                 .....................hgsagcsaaal---------.......----....-.-.......--------------.----.-SLQKP.............RLDS---EH..TAVGVQVTVRKGRGAR..SFRQA.....AVL.VVAM....TKLLRR-..-PTRRDFADSDLSALLEEVFE----pv.................................................
H0YYU7_TAEGU/1-96                   ................................MAFVPDLDT.......L--E....-.-.......SSSLNEETFY--GP.NCLCpQKKPRL.............DLEG---TS..PGVGIQVTVTKGPLSR..TFRQA.....AVL.VVAV....TKLLKQ-..-PSRKDFADSDLGSFLDDIFE----pv.................................................
IL1A_PIG/1-109                      ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSDIDH.LSLNqKSFYDA.............SYEPLPGDG..MDKFMPLSTSKTSKTSrlNFKDS.....VVM.AAAN...gKILKKRR..LSLNQFITDDDLEAIANDT-EEEII...................................................
A0A1U7Q4M0_MESAU/1-111              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYNSAIDH.LSLSqKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMSslTFEES.....LVM.VAATsdkgKILKKRR..LGFNQAFAEDDLETITRNL-EET--i..................................................
A0A1U7TBU6_TARSY/1-103              ................................MATVPEPAS.......EMMD....Y.Y.......SSNEDDLFFEVDGP.KQMK.CSFQNL.............DVCP-----..LDEGIHLQISHQHHNK..SFRQI.....VSV.IVAV....EKLQKML..VPCPKAFQDNDLSALLSFIFEEEAI...................................................
G3QLV0_GORGO/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYHV.............TYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLKKRR..LSLSQSITDDDLEAIANDS-EEEII...................................................
F1MAF9_RAT/1-102                    ................................MAKVPDLFE.......DLKN....C.Y.......--R---ETESSFYH.LSLNqKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILKKRR..LSFNQPFTEDDLEAIAH--------...................................................
A0A218UCE5_9PASE/1-96               ................................MAFVPDLDT.......L--E....-.-.......SSSLNEETFY--GP.NCLCpQKKPRL.............DLEG---TS..PGVGIQVTVTKGTLSR..TFHQA.....AVL.VVAV....TKLLKQ-..-PSRKDFSDSDLGSFLDDIFE----pv.................................................
IL1B_PIG/1-102                      ................................MAIVPEPAK.......EVMA....N.Y.......GDNNNDLLFEADGP.KEMK.CCTQNL.............DLGS----L..RNGSIQLQISHQLWNK..SIRQM.....VSV.IVAV....EKPMKN-..-PSSQAFCDDDQKSIFSFIFEEEPI...................................................
IL1A_RAT/1-111                      ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSAIDH.LSLNqKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILKKRR..LSFNQPFTEDDLEAIAHDL-EET--i..................................................
A0A0A0MPZ7_FELCA/1-100              ................................MAKVPDLFE.......DLKN....C.Y.......----------SFHV.PSSQ.KSFYDA.............SYDPLHEDC..TDKFMSPSTSETSKTPqlTLKKS.....VVM.VAAN...gKILKKRR..LSLNQFLTADDLEAIANEV-EEEI-m..................................................
H2QIK6_PANTR/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....VSV.VVAM....DKLRKML..VPCPQTFQENDLSTFFPFIFEEEPI...................................................
S9X0V8_CAMFR/4-111                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYGSEIDH.LSLNqKSFYDA.............SYEPLQEDC..MDKLMSLSTSETSKTSklTFKES.....VVM.VASN...gKILKKRR..LSLNQFITNDDLEAIANDT-EE---at.................................................
F1LQB1_RAT/1-108                    ................................MAKVPDLFE.......DLKN....C.Y.......--R---ETESSFYH.LSLNqKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILKKRR..LSFNQPFTEDDLEAIAHDL-EET--i..................................................
A3DTN5_MELGA/1-94                   mafvpdldvlessslseetfygpsclclqkkp---------.......----....-.-.......--------------.----.------.............RLD---SEH..TAVGVQVTVRKGRGAR..SFRQA.....AVL.VVAM....TKLLRR-..-PTRRDFADSDLSALLEEVFE----pv.................................................
IL1B_RAT/1-102                      ................................MATVPELNC.......EIAA....F.-.......DSEENDLFFEADRP.QKIK.DCFQAL.............DLG-----C..PDESIQLQISQQHLDK..SFRKA.....VSL.IVAV....EKLWQLP..MSCPWSFQDEDPSTFFSFIFEEEPV...................................................
F6RH14_CALJA/1-103                  ................................MAEVPELTS.......EMMT....Y.Y.......SGNEDDLFFEVDGP.KQMK.CSFQDL.............DLCP-----..VDGGIQLRLSRQHYSK..GFRQV.....VSV.VVAM....EKLRRMP..VYCPQTFQDNDLSTFFPFIFEEEPI...................................................
A0A2C9F3A1_PIG/1-101                ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
F6X1Q9_XENTR/3-109                  ................................MALVPDLSS.......IPME....S.-.......-CSGDDEMFYSDSP.PGMK.DSMKDDs..........qwHSHPGHCSQ..YNLDIHLQITQAKGSL.qSFKKA.....VIL.VVAV....EKLKR--..-GKETFFGDADLLGLLDSIFVEEEI...................................................
O73909_CHICK/1-94                   mafvpdldvlessslseetfygpsclclqkkp---------.......----....-.-.......--------------.----.------.............RLDS---EH..TTVDVQVTVRKGRGAR..SFRRA.....AVL.VVAM....TKLLRR-..-PRSRDFADSDLSALLEEVFE----pv.................................................
L5KTV2_PTEAL/1-104                  ................................MAAVPELAS.......EAMA....Y.Y.......SGNENDLFFEADGP.TQTK.RPFHNL.............ELGS----L..GDSGIQLQVSPQLCST..SPGQV.....VSV.LVAL....EELRAVP..TVCTQDLQEDDLRSLFFFIFEEEP-l..................................................
A0A287BRB4_PIG/1-105                ................................MATVPEPAK.......EVMQalcfY.Y.......SDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
A0A2K5K1S5_COLAP/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYDV.............SYDPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VATN...gKVLKKRR..LSLSQSITDDDLKAITSDS-EEEII...................................................
L9JLW9_TUPCH/1-103                  ................................MAVVPELAN.......EMMD....Y.Y.......SAEEDYLLFEADGP.KQTK.SFYQDV.............DFCS-----..PDKGIQLQISHQSYDK..SFKKF.....VSV.IVAV....EKLKKTL..VPCPQDFQDIDLSILFSLIFDEKPI...................................................
U3JBA2_FICAL/1-96                   ................................MAFVPDLDT.......LESN....-.-.......--SLNEEMLY--GP.NCLCpQKKPRL.............DLEV---TS..PGVGIQVTVTKGHLSR..TFRQA.....AVL.VAAV....TKLLKQ-..-PSHNDFSDSDLGSFFDDIFE----pv.................................................
A0A1S3FFR2_DIPOR/1-102              ................................MAAVPELTS.......EMMA....Y.H.......-SDENDLFFETDGP.KQMK.CCLQDL.............DLCY-----..PDEGIQLQLSHQYFNK..SFRQV.....VSL.IVAV....EKLRNKP..IPCSQAFQNDDLKTFFSIIFEEEP-m..................................................
A0A1U7T5G9_TARSY/1-110              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSTIDH.LSLNqKSFYAG............iSYGELHEDY..TDHSMSLSTSETSKTSklTIKET.....VVR.VAAS...gKILKKRR..LSLNQLITDDDLEAIANDS-EEEII...................................................
A0A287AFR7_PIG/1-41                 ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK.V-----.............---------..----------------..-----.....---.----....-------..-------------------------rpyssrp............................................
A0A2I3HN27_NOMLE/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK.CPFQDL.............DLCP-----..LDGGIQLRISHQHYSK..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLFPFIFEEEPI...................................................
IL1A_FELCA/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LTLNqKSFYDA.............SYDPLHEDC..TDKFMSPSTSETSKTPqlTLKKS.....VVM.VAAN...gKILKKRR..LSLNQFLTADDLEAIANEV-EEEI-m..................................................
IL1A_SHEEP/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLNqKSFYDA.............SYEPLREDH..MNKFMSLDTSETSKTSrlSFKEN.....VVM.VTAN...gKILKKRR..LSLNQFITDDDLEAIANDT-EEEII...................................................
IL1A_CERAT/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LFLNqKSFYDV.............SYGPLHESC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSIADDNLEAIANDS-EEEII...................................................
G1LW58_AILME/1-105                  ................................MAKVPDLFE.......DLKN....C.C.......--SENEEYSSEIDH.LSLNqKSFYDV.............SYDPLHEDC..M----SLSTSETSKTSqlTFKEN.....VVV.VATN...gKILKKRR..LSLNQFITDDDLEAITNDA-EEEI-m..................................................
G1TXR4_RABIT/16-96                  ......................haptdclvsp---------.......----....-.-.......--------------.---Q.SCFQDL.............DLC-----C..PDEGIQLRISCQPYNK..SFRQV.....LSV.VVAL....EKLRQKA..VPCPQAFQDDGLRTFFSLIFEEEPV...................................................
IL1B_FELCA/1-103                    ................................MAPVPELTS.......EMMA....Y.Y.......-SDENDLFFEADGP.EKMK.GSLQNL.............SHSF----L..GDEGIQLQISHQPDNK..SLRHA.....VSV.IVAM....EKLKKIS..FACSQPLQDEDLKSLFCCIFEEEPI...................................................
A0A1S2ZW61_ERIEU/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SEDEVYSSEVDH.ISLNqKSFYHA.............TYEPFHEKS..MDNFMSLSTFEISKTSnhTFKES.....TLM.VAAS...gKILKKRR..FSLNQFLTDDDLEAIANDP-EEEII...................................................
B7ZSG9_XENLA/1-104                  ................................MALVPDLSS.......IPME....G.Y.......--SGDDEMFYSDSP.SGMK.DDMEDA.............AQWQSSTSH..CSLDIHVQITHGKGSL.hSFRKA.....VVL.VVAV....EKLKR--..-GKERFFGDEDLLGLLDSIFVEEEI...................................................
IL1B_RABIT/1-103                    ................................MATVPELTS.......EMMA....Y.H.......SGNENDLFFEADGP.NYMK.SCFQDL.............DLC-----C..PDEGIQLRISCQPYNK..SFRQV.....LSV.VVAL....EKLRQKA..VPCPQAFQDDGLRTFFSLIFEEEPV...................................................
A0A1V4KH82_PATFA/1-96               ................................MAFVPDLDT.......LE--....-.-.......SSSLTEETFYGPNC.LCLQkKPHLDL.............EVT-----S..PGVGIEVMATKGHPTG..TFRRA.....AVL.MVAV....TKLLKR-..-PVHKDFADSDLGDFLDDIFE----pv.................................................
B1AB80_HORSE/1-103                  ................................MAAVPD-TS.......DMMT....Y.C.......SGNENDLFFEEDGP.KQMK.GSFQDL.............DLSS----M..GDGGIQLQFSHQLYNK..TFKHV.....VSI.IVAM....EKLKKIP..VPCSQAFQDDDLRSLFSVIFEEEPI...................................................
F6SEZ4_MONDO/6-96                   ................................MARVPDVLE.......AL--....-.H.......--SENEGFISDIGQ.ASLGqDSFYP-.............SFSSH---H..KERWSSPEFSKKAHQL..NFQEG.....MAA.PVSQ....RKVKKKR..RPFKNH-------------------ypsdndslpe.........................................
S7Q8Z4_MYOBR/1-109                  ................................MAQVPDLFE.......DLKS....C.Y.......--SENEEYSSEIDQ.LSLSqKSFYDA.............SYDPLPKNC..MGQFLSLSTAGTSKTSqlTYKES.....VVV.VAAN...gKILKKRR..LSFNQFITNDDVETIANDP-EEEI-l..................................................
H2UVE2_TAKRU/1-76                   ..........................mesqmk---------.......----....-.-.......--------------.----.----SN.............ESK-MLQSQ..MPEGLELEITHHPL--..TMKSV.....VNL.VIAM....ERLKGNRseSLLSTEFRDENLLSMMMDTIVEEQI...................................................
Q712K7_ORNAN/1-117                  ................................MARVPDQSR.......DLME....C.Y.......SGDGEDQFYEVDGP.SQIK.SGFQDLkartcqetrihkeDKCS----P..CQMGIELKVTELPSSH..GFRKA.....VVL.VVAV....ERIKRQA..VSYNTSFMDRDLMDIFTSIFKEEPI...................................................
A0A093NUK4_PYGAD/1-96               ................................MAFVPDLDT.......--LE....-.-.......SSSLNEETFYGPDC.LCLEkKPCLDS.............EVTS-----..PGVGIQVTVANRHPTR..TFRQA.....ATL.VVAV....TKLLRQ-..-PTHKGFTDSDLGGFLDDIFE----pv.................................................
A0A2K5NF39_CERAT/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYDV.............SYGPLHESC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSIADDNLEAIANDS-EEEII...................................................
F6SXC0_MONDO/1-114                  ................................MATVPEMAC.......DVMD....F.YsffgfvyRDNDDSQFYEADGP.NQKKqGHLQYP.............DLCSKKCLL..EEDGIQLKFTAQSQ--..RFYRS.....VVV.VVAI....EKMRHLV..ELSSGLFQDNDLMNIFTSIFQEEPI...................................................
H2QIK5_PANTR/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLKKRR..LSLSQSITDDDLEAIANDS-EEEII...................................................
A0A151MMR4_ALLMI/1-92               .............................met---------.......----....-.C.......SMS-EECFYEADYP.STVKgYSAAPL.............SPG---ESG..CGMNVQLQFTEPKTHR..GFRTT.....VVL.VVAV....EKMRRM-..PQSPQLFSDCDLLNLFNAVFE----pvp................................................
A0A1A6HM55_NEOLE/1-102              ................................MATVPEFNS.......EMTA....F.H.......-SDDNDVFFEVDGP.QKMK.CCFQAA.............DLSY-----..PDESIQLQISQQHFNK..SFSQV.....VSL.IVAV....EKLWNIP..VPCPWTFQDEDLRTFFSFIFEEEPI...................................................
C9JWV2_HUMAN/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLRKML..VPCPQTFQENDLSTFFPFIFEEEPI...................................................
IL1A_HUMAN/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLKKRR..LSLSQSITDDDLEAIANDS-EEEII...................................................
M7AWZ8_CHEMY/58-162                 ................................MAAVPDVQE.......ELME....F.C.......-SVNDEQFYEVDHP.YLGK.SSNQGS.............SPCSLSQSCsaCDLGIQLQFTEQTSPK..VFRRS.....VVL.VIAT....EKMKKA-..-LKARPFTDDDLTGIFDTVFE----ti.................................................
A0A287B6V6_PIG/35-106               ............................iypq---------.......----....-.-.......--------------.----.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
A0A096NEW1_PAPAN/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLQISHEHYNR..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLIPFIFEEEPV...................................................
IL1B_CAVPO/1-102                    ................................MAAVPELSS.......EVTA....Y.H.......-SDENELFFEVDGP.NKMQ.YCFQDR.............DLCS-----..LDEGIKLQISHQHFNK..SFRQT.....VSL.IVAV....EKLRKKL..APCTWAFQDDDLRPLLPFIFEEEPI...................................................
A0A0G2K003_RAT/1-109                ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYS--LDH.LSLNqKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILKKRR..LSFNQPFTEDDLEAIAHDL-EET--i..................................................
A0A1A6HKM2_NEOLE/2-87               ............................eipl---------.......----....-.-.......--------------.-TKS.KSFYDA.............SYGSLHETC..TDKFISLRASETSRMSnfTFEES.....LVM.VAATsnqgKVLKKRR..LGFNQAFAEDDLEAITHNL-EET--i..................................................
A0A091D3R2_FUKDA/1-101              ................................MAAVPEFSD.......EVTA....Y.H.......-SDENEMFFEIDGP.KQ-Q.YCFQDL.............DLCS-----..LDEGIELQISHQHFNK..SFRQV.....VSL.IVAV....KKLRKEL..VPCPWTFQDNDLKTFFPFIFEEEPI...................................................
A0A140T838_BOVIN/1-101              ................................MATVPEPIN.......EMMA....Y.Y.......-SDENELLFEADGP.KQMK.SCIQHL.............DLGS----M..GDGNIQLQISHQFYNK..SFRQV.....VSV.IVAM....EKLRNS-..-AYAHVFHDDDLRSILSFIFEEEPV...................................................
IL1B_HUMAN/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLRKML..VPCPQTFQENDLSTFFPFIFEEEPI...................................................
G1LW44_AILME/1-104                  ................................MARVPEPTS.......EMSY....Y.C.......SDSENDLSFEADGP.SKMK.CCFQDL.............NSSF----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLKKIS..LPSSQLFQDDDLKNVFSCIFEEEPI...................................................
IL1A_CAVPO/1-107                    ................................-------FE.......DLKN....C.Y.......--SENEEYASAIDH.LSLNqKSFYDT.............NYDPLHENR..VDEPVSPNPYENSEESnfTLEDSsdssaVVL.TSAH...gEVLKKRR..LSLNQTMSNEDLEAIANDS-EEEII...................................................
IL1B_MUSPF/1-105                    ................................MARVPEPTS.......EVMS....YgY.......SDNENDLFFEADGP.GKMK.CCFQDL.............NNSY----L..EEEGIQLQISHQLHNK..SLSHF.....VSV.IVAL....EKLKKIS..VPCSLPLQGDDLMNVFHCIFEEEPI...................................................
A0A087QNQ2_APTFO/1-96               ................................MAFVPDLDT.......--LE....-.-.......SSSLNEETFYDPDC.LYLQkKPCLDS.............EVTS-----..PGVGIQVTVTHGQPTR..TFRRA.....ATL.VVAV....TKLLKQ-..-TMHKDFTDSDLGGFLDDIFE----pv.................................................
M3YEA4_MUSPF/1-112                  ................................MAKVPDLFEdlqifkkDLKN....C.Y.......--SENEEYSSEIDH.LSLSqKSFYDV.............NYDPLHEDC..M----SLRTSETSKTShlTFKED.....VVM.VAAS...gKILKKRR..LSLNQFITDDDLEVITNDT-EEEI-m..................................................
IL1A_BOVIN/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLNqKSFYDA.............SYEPLREDQ..MNKFMSLDTSETSKTSklSFKEN.....VVM.VAAS...gKILKKRR..LSLNQFITDDDLEAIANNT-EEEII...................................................
G3QU53_GORGO/1-103                  ................................MAEVPELTS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISHQHYSK..GFRQA.....VSV.VVAM....DKLRKML..VPCPQTFQENDLSTFFPFIFEEEPI...................................................
A0A226P217_COLVI/1-94               ................................MAFVPDLD-.......-VLE....S.N.......SLSEETFYSSACLC.LQKK.P-----.............RLDS---ER..TAMGMQVTVRKGHSAQ..SFRQA.....AEL.VVAM....TKLLQR-..-PTRKDFADSDLSMLLEEVFE----pv.................................................
G3SN89_LOXAF/1-109                  ................................MAKVPDLFE.......DLKD....C.Y.......--SENEEYSSNNDT.LSLIqKSFYDA.............NYGPLQEVC..MDKFMSLSTSETSKIAkpAFKES.....VAV.VSAT...gKILKKRR..LSLNQPITDEDLEAIANDP-EEEII...................................................
A0A2K5LYI4_CERAT/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLIPFIFEEEPV...................................................
IL1B_SHEEP/1-101                    ................................MATVPEPIN.......EVMA....Y.Y.......-SDENELLFEVDGP.KQMK.SCTQHL.............DLGS----M..GDGNIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLRSR-..-AYEHVFRDDDLRSILSFIFEEEPV...................................................
A0A2I2UR90_FELCA/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LTLNqKSFYDA.............SYDPLHEDC..TDKFMSPSTSETSKTPqlTLKKS.....VVM.VAAN...gKILKKRR..LSLNQFLTADDLEAIANEV-EEEI-m..................................................
U3JBA1_FICAL/1-95                   ................................MAFVPDLDT.......LESN....-.-.......--SLNEEMLY--GP.NCLCpQKKPRL.............DLEV---TS..PGVGIQVTVTKGHLSR..TFRQA.....AVL.VAAV....TKLLKQ-..-PSHNDFSDSDLGSFFDDIF-----gm.................................................
A0A096NPG5_PAPAN/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSIADDHLEAIANDS-EEEII...................................................
A0A2K5JR15_COLAP/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDHLFFEVDGP.KEMK.CSFQDL.............DLCP-----..LDGVIQLRISHEHYSK..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLNTLFPFIFEEEPI...................................................
H0W1R8_CAVPO/1-114                  ................................MAQCPNMLE.......DLKS....C.Y.......--SENEEYASAIDH.LSLNqKSFYDT.............NYDPLHENR..VDKPVSPNPYENSEESnfTLEDSsdssaVVL.TSAH...gEVLKKRR..LSLNQTMSNEDLEAIANDS-EEEII...................................................
A0A2I3N9K4_PAPAN/1-93               ................................MAEVPELAS.......EMMA....Y.Y.......---------RSVGT.--LRqCSFQDL.............DLCP-----..LDGGIQLQISHEHYNR..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLIPFIFEEEPV...................................................
A0A2I3LTT5_PAPAN/1-101              ................................MAKVPDMFE.......DLKN....C.Y.......---------RCISC.DLMK.KSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSIADDHLEAIANDS-EEEII...................................................
V8PGF3_OPHHA/156-223                ......................dwllftfqka---------.......----....-.-.......--------------.----.------.............--------F..QDSKVDVQVAVTKNEPlkSFRKA.....VLI.VIAS....ETMRK--..-SPASLFSDEDLLDILSTILE----pv.................................................
G1NSN5_MYOLU/1-109                  ................................MAQVPDLFE.......DLKS....C.Y.......--SENEEYSSEIDQ.LSLNqKSFYDA.............SYDPFPKNC..MGQFLSLSTSETSKTSqlTYKES.....VVV.VAAN...gKILKKRR..LSFNQFITDDDLETIANDP-EEEI-l..................................................
A0A2G9RS62_LITCT/1-103              ................................MAVVPEIND.......LPMD....S.Y.......--SEEEFYSECSTE.MKVDtNHFGWK.............GCIS-SQSS..CRSSITRDIRKPRKPM.sSLKKA.....INL.VVII....GRVSG-K..KNFECLFDDQDLLNY----------ilveedi............................................
A0A287AKL5_PIG/2-101                ......................cpgditeqal---------.......--CF....Y.Y.......SDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
G3I1B0_CRIGR/1-72                   ................................---------.......----....-.-.......--------------.--MK.CCFQSL.............DLSY-----..PDESIQLQITKQHHNK..SFRQV.....VSV.IVAV....EKLWNIP..VAGPWTLQDEDLRTFFSFIFEEEPI...................................................
H2P5G1_PONAB/1-111                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFLSXx..........xxSYGPLHEGC..MDQSVSLSISETSKHP.gLLHES.....MVV.VATN...gKVLKKRR..LSLSQSITDDDLQAIANGS-EEEII...................................................
G3STJ8_LOXAF/1-100                  ................................MAAVPELFG.......DVRN....Y.Y.......SDNEDDLFFEPDGP.KQMK.CCFQDL.............DLCS----P..GDGGIRLQISQQHYNK..SFKQV.....VSV.IVAV....EKLKTIL..VPCSQSF----LTNLFSFIFEEEPI...................................................
F6VT34_CALJA/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSSIDH.LSLNqKSFYDV.............NYGSHHEEC..MDQSVSLSISETSKTSklTFKES.....VVI.VSTN...gKVLKKRR..LTLNHSITDDDLEGIANDI-EEEII...................................................
A0A140T8E9_CANLF/1-105              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLNqKSFYDM.............SCDPLHEDC..M----SLSTSEISKTSqlTFKEN.....VVV.VAAN...gKILKKRR..LSLSQFITDDDLEDIANDT--EEVIm..................................................
F7G8K0_MACMU/1-62                   ................................---------.......----....-.-.......--------------.----.------.............---------..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSITDNNLEAIANDS-EEEII...................................................
S7NJ59_MYOBR/1-104                  ................................MAAVPELTN.......EVMA....Y.Y.......SDNENDLFFEADGP.QQTK.CSFQDL.............DLSP----L..GDGGIQLKVSHQLCNS..SFRRA.....VSV.VIAV....EKLRKVP..MFCPKDFQDDDLRSLFFFIFKEESI...................................................
G1QMS9_NOMLE/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLKKRR..LSLSQSITDDDLEAITNDS-EEEII...................................................
A0A2G9RQ98_LITCT/32-134             ................................MAVVPEIND.......LPMD....S.Y.......--SEEEFYAECSSE.MKVDtNHFGWK.............GCIS-SQSS..CRSSITREIRKPRKPI.pSLKKA.....INL.VVII....GRVSG-K..NHFECLFDDQDLLNH----------ilveedi............................................
A0A287AFR7_PIG/35-78                ...........................rpyss---------.......----....-.-.......--------------.----.------.............---------..----------------..--RPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
H2P5G2_PONAB/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISHQHYSK..GFKQA.....VSV.VVAM....DKLRKML..VPCPQNFQDNDLSTFFPFIFEEEPI...................................................
I3M051_ICTTR/1-89                   ................................MAAVPELAS.......EMMA....Y.H.......-SDENDLFFEVDGP.KHMK.PIFCDP.............---------..----------------..-----.....---.----....-------..-------------------------wdddgyeydaavpvlncrlrdvqqkslvlsdpcelkalhlngpnlrqqvvf
C9JVK0_HUMAN/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLRKML..VPCPQTFQENDLSTFFPFIFEEEPI...................................................
A0T125_CANLF/1-95                   ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLNqKSFYDM.............SCDPLHEDC..M----SLSTSEISKTSqlTFKEN.....VVV.VAAN...gKILKKRR..LSLSQFITDDDLE------------d..................................................
G7PMZ6_MACFA/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLNqKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSITDNNLEAIANDS-EEEII...................................................
A0A0D9RW29_CHLSB/1-62               ................................---------.......----....-.-.......--------------.----.------.............---------..MDQSVSLSIYEISKTSklTFKQS.....MVV.VSTN...gKVLKKRR..LSLSQSITDNNLEAIANNS-EEEII...................................................
H0WRY2_OTOGA/1-104                  ................................MARVPDLFE.......D---....Y.Y.......--SENEEHSSAFDQ.LCLNqKSFYDA.............SHSSHNKDC..VDQFMCLSACETSKGSgcTVQES.....VVL.VTAK...gKVLKKRR..FNLDQSITDDDLEAIPHDK-K----ev.................................................
G7PMZ7_MACFA/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLRKML..VPCPQIFQDNDLSTLIPFIFEEEPV...................................................
F1SUB9_PIG/1-101                    ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
IL1B_MACMU/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK.CSFQDL.............DLCP-----..LGGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLRKML..VPCPQIFQDNDLSTLIPFIFEEEPV...................................................
C9JSC2_HUMAN/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLRKML..VPCPQTFQENDLSTFFPFIFEEEPI...................................................
A0A287A4B5_PIG/3-100                ........................gditeqal---------.......--CF....Y.Y.......SDNNNDLLFEADGP.KEMK.CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPMN--..-PSSQVVCDDDPKSIFSSVFEEEPI...................................................
W5QI89_SHEEP/42-150                 ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLNqKSFYDA.............SYEPLREDH..MNKFMSLDTSETSKTSrlSFKEN.....VVM.MTAN...gKILKKRR..LSLNQFITDDDLEAIANDT-EEEII...................................................
H2UVE3_TAKRU/1-76                   ..........................mesqmk---------.......----....-.-.......--------------.----.----SN.............ESK-MLQSQ..MPEGLELEITHHPL--..TMKSV.....VNL.VIAM....ERLKGNRseSLLSTEFRDENLLSMMMDTIVEEQI...................................................
G5B006_HETGA/35-136                 ................................MAAVPEFSN.......EVTA....Y.H.......-SDENEMFFEVDGP.KQMK.HCFQDL.............DLCS-----..LDEGIELQISHQHFKK..SFQQV.....VSL.IVAV....EKLRKEL..VPCPWTFQDNDLRTFFPFIFEEEPI...................................................
IL1B_CERAT/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SSNEDDLFFEVDGP.KQMK.CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLRKML..VPCPQTFQDNDLSTLIPFIFEEEPV...................................................
L5LRV7_MYODS/1-109                  ................................MAQVPDLFE.......DLKS....C.Y.......--SENEEYSSEIDQ.LSLNqKSFYDA.............SYDPLPKNC..MGRFLSLSTSETSETSqlTYKES.....VVV.VAAN...gKILKKRR..LSFNQFITDDDLETIANDP-EEEI-l..................................................
H0WRY4_OTOGA/1-103                  ................................MAAVPELTS.......EMMD....Y.Y.......SGNEDDLFFEAEGS.KQMK.CSFQDL.............DLCP-----..TDGGIQLHVSHQHYNK..DFRQV.....VSL.IVAM....EKLRNKP..VLCPKAFQDGDLSTFFPFIFEEEPI...................................................
F7CCI7_HORSE/1-103                  ................................MAAVPD-TS.......DMMT....Y.C.......SGNENDLFFEEDGP.KQMK.GSFQDL.............DLSS----M..GDGGIQLQISHHLYNK..TFKHA.....MSI.IVAV....EKLKKIP..VPCSQAFQDDDLRSLFSVIFEEEPI...................................................
#=GC seq_cons                       ................................MApVP-lhp.......-hhs....h.Y.........sEN-.h.ps.s..hphp.psF.-h.............shss....h..hDtulpLplScpptsp..oF+pu.....Vsl.VlAh....c+L+Kh...lshsQshpD-DLpslhstl.EEE.l...................................................
//
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