GenomeNet

Database: Pfam
Entry: IL1_propep
LinkDB: IL1_propep
Original site: IL1_propep 
#=GF ID   IL1_propep
#=GF AC   PF02394.17
#=GF DE   Interleukin-1 propeptide
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_1500 (release 5.2)
#=GF GA   21.30 21.30;
#=GF TC   21.30 21.60;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR003502;
#=GF DR   PROSITE; PDOC00226;
#=GF DR   SCOP; 2mib; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The Interleukin-1 cytokines are translated as precursor
#=GF CC   proteins.  The N terminal approx. 115 amino acids form a
#=GF CC   propeptide that is cleaved off to release the active
#=GF CC   interleukin-1.
#=GF SQ   217
#=GS A0A0Q3X8K9_AMAAE/3-94    AC A0A0Q3X8K9.1
#=GS IL1B_DELLE/1-101         AC Q8WNR2.1
#=GS A0A2Y9Q796_DELLE/1-109   AC A0A2Y9Q796.1
#=GS G1PEV6_MYOLU/1-104       AC G1PEV6.1
#=GS F7CCI7_HORSE/1-103       AC F7CCI7.2
#=GS M4WG34_SHEEP/1-101       AC M4WG34.2
#=GS A0A2Y9T9X2_PHYMC/1-109   AC A0A2Y9T9X2.1
#=GS L5KV65_PTEAL/1-109       AC L5KV65.1
#=GS I3M045_ICTTR/1-109       AC I3M045.1
#=GS Q5BKB0_RAT/1-102         AC Q5BKB0.1
#=GS A0A287BHV2_PIG/1-105     AC A0A287BHV2.1
#=GS A0A2U4B011_TURTR/18-118  AC A0A2U4B011.1
#=GS IL1A_RABIT/1-109         AC P04822.1
#=GS IL1B_MOUSE/1-102         AC P10749.1
#=GS IL1B_MACFA/1-103         AC P79182.1
#=GS G3W2K5_SARHA/1-98        AC G3W2K5.1
#=GS F6SEZ4_MONDO/6-95        AC F6SEZ4.1
#=GS A0A091D913_FUKDA/1-111   AC A0A091D913.1
#=GS A0A340WC10_LIPVE/1-101   AC A0A340WC10.1
#=GS A0A452E7H6_CAPHI/1-95    AC A0A452E7H6.1
#=GS A0A452SK12_URSAM/1-84    AC A0A452SK12.1
#=GS A0A2K5R5T1_CEBCA/1-103   AC A0A2K5R5T1.1
#=GS Q2VCE2_CANLF/1-101       AC Q2VCE2.1
#=GS IL1B_BOVIN/1-101         AC P09428.2
#=GS A0A1U7Q9G0_MESAU/1-102   AC A0A1U7Q9G0.1
#=GS A0A2K5VDH8_MACFA/1-93    AC A0A2K5VDH8.1
#=GS IL1A_CANLF/1-105         AC O46612.1
#=GS L9JMH4_TUPCH/1-109       AC L9JMH4.1
#=GS A0A0M3KL74_CHLSB/1-72    AC A0A0M3KL74.1
#=GS A0A287AFR7_PIG/1-39      AC A0A287AFR7.1
#=GS A0A2K6DC85_MACNE/1-103   AC A0A2K6DC85.1
#=GS A0A384CVD5_URSMA/1-105   AC A0A384CVD5.1
#=GS A0A3Q7RVJ7_VULVU/1-101   AC A0A3Q7RVJ7.1
#=GS A0A2K5NFE1_CERAT/16-86   AC A0A2K5NFE1.1
#=GS A0A3P8SXI1_AMPPE/9-89    AC A0A3P8SXI1.1
#=GS A0A2K5ZAA3_MANLE/1-93    AC A0A2K5ZAA3.1
#=GS A0A287B6X4_PIG/1-101     AC A0A287B6X4.1
#=GS A0A2K5BVG7_AOTNA/2-101   AC A0A2K5BVG7.1
#=GS IL1B_HORSE/1-103         AC Q28386.1
#=GS A0A2K5LYJ6_CERAT/1-93    AC A0A2K5LYJ6.1
#=GS A0A2K5BVQ1_AOTNA/1-103   AC A0A2K5BVQ1.1
#=GS A0A3M0IUH0_HIRRU/1-96    AC A0A3M0IUH0.1
#=GS A0A2K5VDE4_MACFA/35-137  AC A0A2K5VDE4.1
#=GS A0A3Q7UJN8_URSAR/30-133  AC A0A3Q7UJN8.1
#=GS G3W4G1_SARHA/1-105       AC G3W4G1.1
#=GS A0A384BCQ4_BALAS/1-109   AC A0A384BCQ4.1
#=GS F7G8J2_MACMU/1-103       AC F7G8J2.1
#=GS IL1A_MACFA/1-109         AC P79340.1
#=GS A0A1S2ZW37_ERIEU/1-103   AC A0A1S2ZW37.1
#=GS A0A286ZMX3_PIG/1-100     AC A0A286ZMX3.1
#=GS A0A2K6U6E7_SAIBB/1-103   AC A0A2K6U6E7.1
#=GS IL1A_MOUSE/1-111         AC P01582.1
#=GS IL1A_HORSE/1-109         AC Q28385.1
#=GS G5B005_HETGA/1-111       AC G5B005.1
#=GS A0A1S3FGQ2_DIPOR/1-111   AC A0A1S3FGQ2.1
#=GS A0A3Q7S5W9_VULVU/1-105   AC A0A3Q7S5W9.1
#=GS IL1B_CANLF/1-102         AC Q28292.2
#=GS R7VSW8_COLLI/1-96        AC R7VSW8.1
#=GS IL1A_MACMU/1-109         AC P48089.1
#=GS H9H271_MELGA/44-121      AC H9H271.1
#=GS H0YYU7_TAEGU/1-96        AC H0YYU7.1
#=GS A0A452SK07_URSAM/1-104   AC A0A452SK07.1
#=GS IL1A_PIG/1-109           AC P18430.1
#=GS IL1B_CAPHI/1-101         AC P79162.1
#=GS A0A1U7Q4M0_MESAU/1-111   AC A0A1U7Q4M0.1
#=GS A0A1U7TBU6_TARSY/1-103   AC A0A1U7TBU6.1
#=GS G3QLV0_GORGO/1-109       AC G3QLV0.1
#=GS F1MAF9_RAT/1-102         AC F1MAF9.3
#=GS A0A2Y9E9G0_TRIMA/1-109   AC A0A2Y9E9G0.1
#=GS A0A218UCE5_9PASE/1-96    AC A0A218UCE5.1
#=GS IL1B_PIG/1-102           AC P26889.1
#=GS IL1A_RAT/1-111           AC P16598.1
#=GS H2QIK6_PANTR/1-103       AC H2QIK6.1
#=GS A0A402EJ04_9SAUR/34-139  AC A0A402EJ04.1
#=GS F1LQB1_RAT/1-108         AC F1LQB1.3
#=GS A0A2R9AMR9_PANPA/1-109   AC A0A2R9AMR9.1
#=GS A3DTN5_MELGA/1-94        AC A3DTN5.1
#=GS IL1B_RAT/1-102           AC Q63264.1
#=GS A0A3Q1LXP9_BOVIN/1-108   AC A0A3Q1LXP9.1
#=GS A0A3Q2KRY5_HORSE/4-92    AC A0A3Q2KRY5.1
#=GS A0A3Q7XCZ3_URSAR/4-103   AC A0A3Q7XCZ3.1
#=GS F6RH14_CALJA/1-103       AC F6RH14.1
#=GS A0A2C9F3A1_PIG/1-101     AC A0A2C9F3A1.1
#=GS F6X1Q9_XENTR/3-109       AC F6X1Q9.1
#=GS O73909_CHICK/1-94        AC O73909.1
#=GS H9GZN1_HORSE/1-88        AC H9GZN1.1
#=GS A0A2U3YMJ2_LEPWE/1-105   AC A0A2U3YMJ2.1
#=GS Q32YM7_TRIMA/1-100       AC Q32YM7.1
#=GS L5KTV2_PTEAL/1-104       AC L5KTV2.1
#=GS A0A2U3VWR1_ODORO/1-105   AC A0A2U3VWR1.1
#=GS A0A287BRB4_PIG/1-105     AC A0A287BRB4.1
#=GS A0A2K5K1S5_COLAP/1-109   AC A0A2K5K1S5.1
#=GS L9JLW9_TUPCH/1-103       AC L9JLW9.1
#=GS U3JBA2_FICAL/1-96        AC U3JBA2.1
#=GS A0A3Q1DAZ2_AMPOC/8-90    AC A0A3Q1DAZ2.1
#=GS A0A1S3FFR2_DIPOR/1-102   AC A0A1S3FFR2.1
#=GS A0A1U7T5G9_TARSY/1-110   AC A0A1U7T5G9.1
#=GS A0A2K6UJQ1_SAIBB/1-109   AC A0A2K6UJQ1.1
#=GS A0A2I3HN27_NOMLE/1-103   AC A0A2I3HN27.1
#=GS A0A287AFR7_PIG/36-78     AC A0A287AFR7.1
#=GS A0A4D9DQQ0_9SAUR/1-102   AC A0A4D9DQQ0.1
#=GS IL1A_FELCA/1-109         AC O46613.1
#=GS IL1A_SHEEP/1-109         AC Q28579.1
#=GS IL1A_CERAT/1-109         AC P46647.1
#=GS G1LW58_AILME/1-105       AC G1LW58.1
#=GS G1TXR4_RABIT/16-96       AC G1TXR4.1
#=GS Q9TTK2_TURTR/1-109       AC Q9TTK2.1
#=GS IL1B_FELCA/1-103         AC P41687.1
#=GS A0A3Q3LYR4_9TELE/12-96   AC A0A3Q3LYR4.1
#=GS A0A1S2ZW61_ERIEU/1-109   AC A0A1S2ZW61.1
#=GS B7ZSG9_XENLA/1-104       AC B7ZSG9.1
#=GS A0A2U3VWQ9_ODORO/1-105   AC A0A2U3VWQ9.1
#=GS A0A340WGC1_LIPVE/1-109   AC A0A340WGC1.1
#=GS IL1B_RABIT/1-103         AC P14628.1
#=GS A0A2K5YIB2_MANLE/1-109   AC A0A2K5YIB2.1
#=GS A0A2Y9KXY7_ENHLU/1-105   AC A0A2Y9KXY7.1
#=GS A0A0A0MPZ0_FELCA/36-138  AC A0A0A0MPZ0.2
#=GS A0A3Q2H3V0_HORSE/1-103   AC A0A3Q2H3V0.1
#=GS A0A1V4KH82_PATFA/1-96    AC A0A1V4KH82.1
#=GS B1AB80_HORSE/1-103       AC B1AB80.1
#=GS A0A2U3YM52_LEPWE/1-105   AC A0A2U3YM52.1
#=GS A0A2U3YM60_LEPWE/1-104   AC A0A2U3YM60.1
#=GS Q712K7_ORNAN/1-117       AC Q712K7.1
#=GS A0A2K5NF39_CERAT/1-109   AC A0A2K5NF39.1
#=GS A0A2Y9QBK0_DELLE/1-101   AC A0A2Y9QBK0.1
#=GS F6SXC0_MONDO/1-114       AC F6SXC0.1
#=GS A0A2K6DC97_MACNE/1-102   AC A0A2K6DC97.1
#=GS H2QIK5_PANTR/1-109       AC H2QIK5.1
#=GS A0A384BCN2_BALAS/1-101   AC A0A384BCN2.1
#=GS A0A151MMR4_ALLMI/1-92    AC A0A151MMR4.1
#=GS A0A2K6FGM6_PROCO/1-109   AC A0A2K6FGM6.1
#=GS A0A2K5ZAB0_MANLE/1-103   AC A0A2K5ZAB0.1
#=GS A0A1A6HM55_NEOLE/1-102   AC A0A1A6HM55.1
#=GS A0A2R9BYV3_PANPA/1-103   AC A0A2R9BYV3.1
#=GS C9JWV2_HUMAN/1-103       AC C9JWV2.1
#=GS IL1A_HUMAN/1-109         AC P01583.1
#=GS M7AWZ8_CHEMY/58-162      AC M7AWZ8.1
#=GS A0A287B6V6_PIG/35-106    AC A0A287B6V6.1
#=GS A0A096NEW1_PAPAN/1-103   AC A0A096NEW1.1
#=GS A0A0A0MPZ7_FELCA/1-100   AC A0A0A0MPZ7.3
#=GS A0A0G2K003_RAT/1-109     AC A0A0G2K003.1
#=GS IL1B_CAVPO/1-102         AC Q9WVG1.1
#=GS A0A1A6HKM2_NEOLE/2-87    AC A0A1A6HKM2.1
#=GS A0A2Y9FDJ9_PHYMC/1-101   AC A0A2Y9FDJ9.1
#=GS A0A091D3R2_FUKDA/1-101   AC A0A091D3R2.1
#=GS A0A140T838_BOVIN/1-101   AC A0A140T838.1
#=GS A0A2U4B015_TURTR/1-109   AC A0A2U4B015.1
#=GS IL1B_HUMAN/1-103         AC P01584.2
#=GS G1LW44_AILME/1-104       AC G1LW44.1
#=GS A0A2K6R176_RHIRO/1-103   AC A0A2K6R176.1
#=GS A0A2K6MJJ0_RHIBE/1-109   AC A0A2K6MJJ0.1
#=GS IL1A_CAVPO/1-107         AC Q60480.1
#=GS IL1B_MUSPF/1-105         AC A4UYK8.1
#=GS A0A2K6DDD6_MACNE/1-62    AC A0A2K6DDD6.1
#=GS A0A087QNQ2_APTFO/1-96    AC A0A087QNQ2.1
#=GS A0A2K6NJ18_RHIRO/1-109   AC A0A2K6NJ18.1
#=GS M3YEA4_MUSPF/1-112       AC M3YEA4.1
#=GS A0A3P8SW69_AMPPE/2-76    AC A0A3P8SW69.1
#=GS IL1A_BOVIN/1-109         AC P08831.1
#=GS A0A2K5S6C4_CEBCA/1-62    AC A0A2K5S6C4.1
#=GS G3QU53_GORGO/1-103       AC G3QU53.1
#=GS A0A226P217_COLVI/1-94    AC A0A226P217.1
#=GS G3SN89_LOXAF/1-109       AC G3SN89.1
#=GS A0A2K5LYI4_CERAT/1-103   AC A0A2K5LYI4.1
#=GS A0A2U3YM55_LEPWE/1-104   AC A0A2U3YM55.1
#=GS IL1B_SHEEP/1-101         AC P21621.2
#=GS A0A2Y9S2F9_TRIMA/1-108   AC A0A2Y9S2F9.1
#=GS C9WPT5_CYNSE/2-76        AC C9WPT5.1
#=GS U3JBA1_FICAL/1-95        AC U3JBA1.1
#=GS F6VT34_CALJA/1-109       AC F6VT34.2
#=GS A0A493SYV9_ANAPP/1-100   AC A0A493SYV9.1
#=GS A0A096NPG5_PAPAN/1-109   AC A0A096NPG5.1
#=GS A0A2U3ZG75_ODORO/1-104   AC A0A2U3ZG75.1
#=GS A0A2K5JR15_COLAP/1-103   AC A0A2K5JR15.1
#=GS H0W1R8_CAVPO/1-114       AC H0W1R8.2
#=GS A0A3L8RU54_CHLGU/1-96    AC A0A3L8RU54.1
#=GS A0A2I3N9K4_PAPAN/1-93    AC A0A2I3N9K4.1
#=GS A0A2Y9KR26_ENHLU/1-112   AC A0A2Y9KR26.1
#=GS A0A2I3LTT5_PAPAN/1-101   AC A0A2I3LTT5.1
#=GS Q9TTK1_TURTR/1-101       AC Q9TTK1.1
#=GS A0A2K6L2N5_RHIBE/1-103   AC A0A2K6L2N5.1
#=GS G1NSN5_MYOLU/1-109       AC G1NSN5.1
#=GS IL1A_CAPHI/1-109         AC P79161.1
#=GS IL1B_MACNE/1-103         AC P51493.1
#=GS A0A287AKL5_PIG/2-101     AC A0A287AKL5.1
#=GS A0A452SK04_URSAM/1-97    AC A0A452SK04.1
#=GS G3I1B0_CRIGR/1-72        AC G3I1B0.1
#=GS H2UVE3_TAKRU/1-76        AC H2UVE3.2
#=GS G3STJ8_LOXAF/1-100       AC G3STJ8.1
#=GS H2P5G1_PONAB/1-111       AC H2P5G1.1
#=GS A0A140T8E9_CANLF/1-105   AC A0A140T8E9.1
#=GS F7G8K0_MACMU/1-62        AC F7G8K0.2
#=GS I3M051_ICTTR/1-88        AC I3M051.2
#=GS G1QMS9_NOMLE/1-109       AC G1QMS9.2
#=GS F7C3T8_HORSE/1-109       AC F7C3T8.2
#=GS H2P5G2_PONAB/1-103       AC H2P5G2.1
#=GS C9JVK0_HUMAN/1-103       AC C9JVK0.1
#=GS A0T125_CANLF/1-95        AC A0T125.1
#=GS G7PMZ6_MACFA/1-109       AC G7PMZ6.1
#=GS A0A452SK66_URSAM/16-82   AC A0A452SK66.1
#=GS A0A3Q0FJI4_ALLSI/1-89    AC A0A3Q0FJI4.1
#=GS A0A0D9RW29_CHLSB/1-62    AC A0A0D9RW29.1
#=GS A7Y3X8_CAPHI/1-101       AC A7Y3X8.1
#=GS H0WRY2_OTOGA/1-104       AC H0WRY2.1
#=GS A0A2K5VBY6_MACFA/1-101   AC A0A2K5VBY6.1
#=GS A0A384CV32_URSMA/1-104   AC A0A384CV32.1
#=GS A0A2K6FAZ1_PROCO/1-103   AC A0A2K6FAZ1.1
#=GS F1SUB9_PIG/1-101         AC F1SUB9.2
#=GS C9JSC2_HUMAN/1-103       AC C9JSC2.1
#=GS IL1B_MACMU/1-103         AC P48090.1
#=GS A0A287A4B5_PIG/3-100     AC A0A287A4B5.1
#=GS A0A2Y9RYF7_TRIMA/1-100   AC A0A2Y9RYF7.1
#=GS W5QI89_SHEEP/42-150      AC W5QI89.1
#=GS A0A2K5VDC7_MACFA/1-103   AC A0A2K5VDC7.1
#=GS G5B006_HETGA/35-136      AC G5B006.1
#=GS IL1B_CERAT/1-103         AC P46648.1
#=GS H0WRY4_OTOGA/1-103       AC H0WRY4.1
A0A0Q3X8K9_AMAAE/3-94               ................................MAFVPDL--.......DVLE....-.-.......SSSPNEETFYGPDC.LCLQ.kKPRLDL.............EVAS-----..PGVDIQVTVTKGHPAR..TFHQA.....AVL.VAAV....TKPA..H--..----KEFADSDLGGFLDDIFE----pv................................................
IL1B_DELLE/1-101                    ................................MATVPEPTN.......EVMA....Y.Y.......-SDENDLLFEADGP.KQMK..CCVQPL.............DLNS----M..GDGSIHLQISHQLYNK..SLRRV.....VSV.IVAV....EKLQ..K--..IPCSQTFQDDGLRSIFSLIFEEEPV..................................................
A0A2Y9Q796_DELLE/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDA.............SYEPLHQDC..IDKYMSLNTPETSKTSklTFKEN.....VMM.VAAN...gKILK..NRW..LSLNRFLTDDDLEDIADGT-EEEII..................................................
G1PEV6_MYOLU/1-104                  ................................MAAVPELAN.......EVMA....Y.Y.......SDDENGLFFEADGP.QQTK..CSFQDL.............DLSP----L..GDGSIQLKVSQQLYNS..SFRRA.....VSV.VIAV....EKLR..KVH..MVCPQDFQDDDLRSLFFFIFKEESI..................................................
F7CCI7_HORSE/1-103                  ................................MAAVPD-TS.......DMMT....Y.C.......SGNENDLFFEEDGP.KQMK..GSFQDL.............DLSS----M..GDGGIQLQISHHLYNK..TFKHA.....MSI.IVAV....EKLK..KIP..VPCSQAFQDDDLRSLFSVIFEEEPI..................................................
M4WG34_SHEEP/1-101                  ................................MATVPEPIN.......EVMA....Y.Y.......-SDANELLFEVDGP.KQMK..SCTQHL.............DLGS----M..GDGNIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLR..SR-..-AYEHVFRDDDLRSILSFIFEEEPV..................................................
A0A2Y9T9X2_PHYMC/1-109              ................................MAEVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDA.............SYEPLHEDC..MDKFMSLNSSETSKTSklTFKEN.....VGM.VAAN...gKILK..KRW..LSLNQFITNDDLEDIANDT-EEEII..................................................
L5KV65_PTEAL/1-109                  ................................MAKVPDVFE.......DLKN....C.Y.......--SENEEYSSDADQ.LSLN.qKSFYDT.............SYDTLHEDH..GGKLRSLGTSEASKMSqlTFKES.....VVV.LAAD...gKVLK..KRR..LSFDQFITDEDLEAIANDT-KEEPI..................................................
I3M045_ICTTR/1-109                  ................................MAKVPDLFE.......DLKD....C.Y.......--SEDEDYNSTMDH.LSLH.qKSFYTT.............SYHSLGETC..VDKLMSRSTSETSKTSklTFKES.....LVL.VSAN...gKTLK..KRR..LSFHQPISDDDLEAIAYDL-EEEPI..................................................
Q5BKB0_RAT/1-102                    ................................MATVPELNC.......EIAA....F.-.......DSEENDLFFEADRP.QKIK..DCFQAL.............DLG-----C..PDESIQLQISQQHLDK..SFRKA.....VSL.IVAV....EKLW..QLP..MSCPWSFQDEDPSTFFSFIFEEEPV..................................................
A0A287BHV2_PIG/1-105                ................................MATVPEPAK.......EVMQalcfY.Y.......SDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A2U4B011_TURTR/18-118             ................................MATVPEPTN.......EVMA....Y.Y.......-SDENDLLFEADGP.KQMK..CCVQHL.............DLSS----T..GDESIHLQISHQLYNK..SFRHV.....VSV.IVAV....EKLQ..K--..IPCSQTFQDDGLRSIFSLIFEEEPV..................................................
IL1A_RABIT/1-109                    ................................MAKVPDLFE.......DLKN....C.F.......--SENEEYSSAIDH.LSLN.qKSFYDA.............SYEPLHEDC..MNKVVSLSTSETSVSPnlTFQEN.....VVA.VTAS...gKILK..KRR..LSLNQPITDVDLETNVSDP-EEGII..................................................
IL1B_MOUSE/1-102                    ................................MATVPELNC.......EMPP....F.-.......DSDENDLFFEVDGP.QKMK..GCFQTF.............DLG-----C..PDESIQLQISQQHINK..SFRQA.....VSL.IVAV....EKLW..QLP..VSFPWTFQDEDMSTFFSFIFEEEPI..................................................
IL1B_MACFA/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
G3W2K5_SARHA/1-98                   ................................MARVPDIYE.......DLHL....Q.Y.......--SDNEEFISDTHH.VSSS.qDSFYTN.............SSPYQEESC..TKLEISEKIHQLNS--..--QDC.....VDApVVKK....KKEK..KKQ..ISESHPITS----------------nyvfnvgsnl........................................
F6SEZ4_MONDO/6-95                   ................................MARVPDVLE.......AL--....-.H.......--SENEGFISDIGQ.ASLG.qDSFYP-.............SFSSH---H..KERWSSPEFSKKAHQL..NFQEG.....MAA.PVSQ....RKVK..KKR..RPFKN--------------------hypsdndslp........................................
A0A091D913_FUKDA/1-111              ................................MAEVPNLFE.......DLKS....C.Y.......--SENEEYASAIDR.FSLN.qKSFYDT.............SYGPLDENC..MNKSVSLSTLQTSEVSelSFKEN.....LVV.VSTSa.hrKVLK..KRR..LSLNQTITNEDLEAIINGP-EEEII..................................................
A0A340WC10_LIPVE/1-101              ................................MATVPEPTN.......EVMD....Y.Y.......-SDENDLLFEADSP.KQMK..CCVQHL.............DLSS----T..GDGSIHLQISHQLYNK..SFRKV.....VSV.IVAM....EKLQ..K--..VPCSQTFQDDGLRSILSLIFQEEPV..................................................
A0A452E7H6_CAPHI/1-95               ................................MAKVPDLFE.......DLKN....C.Y.......--R-------EARH.IRIH..SYFPSS.............QKS------..FYDFMSLDTSETSKTSrlSFKEN.....VVM.VTAN...gKILK..KRR..LSLNQFITDDDLEAIANDT-EEEII..................................................
A0A452SK12_URSAM/1-84               ................................---------.......----....-.-.......--------SSEIDH.LSLN.qKSFYDV.............SYDPLHEDC..M----SLSTSETSKTSqlTFKEN.....VVV.VATN...gKILK..KRR..LSLNQFITDDDLEAITNDA-EEEI-m.................................................
A0A2K5R5T1_CEBCA/1-103              ................................MAEVPELTS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..MDGGIQLRLSPQHYSK..GFRQV.....VSV.VVAM....EKLR..KMP..VYCPQTFQDNDLSTFFPFIFEEEPV..................................................
Q2VCE2_CANLF/1-101                  ................................MAAVPELTS.......EMMA....Y.S.......SNNENDLFFEADGP.GNVK..CCCQDL.............NHSS----L..VDEGIQLQVSHQLCNK..SLRHF.....VSV.IVAL....EKLK..K--..-PCPQVLQEDDLKSIFCYIFEEEPI..................................................
IL1B_BOVIN/1-101                    ................................MATVPEPIN.......EMMA....Y.Y.......-SDENELLFEADDP.KQMK..SCIQHL.............DLGS----M..GDGNIQLQISHQFYNK..SFRQV.....VSV.IVAM....EKLR..NS-..-AYAHVFHDDDLRSILSFIFEEEPV..................................................
A0A1U7Q9G0_MESAU/1-102              ................................MATVPELDS.......EMIA....F.H.......-SDENDLFFEVDGL.QKMK..SCFQSL.............DLSY-----..PDESIQLQISKQDLNK..SFRQV.....VSV.IVAV....EKLW..NTP..VPCPWTFQDEDLRTFFSFIFEEEPI..................................................
A0A2K5VDH8_MACFA/1-93               ................................MAEVPELAS.......EMMA....Y.Y.......---------RSVGT.--LR.qCSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
IL1A_CANLF/1-105                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDM.............SCDPLHEDC..M----SLSTSEISKTSqlTFKEN.....VVV.VAAN...gKILK..KRR..LSLSQFITDDDLEGIANDT--EEVIm.................................................
L9JMH4_TUPCH/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENAEYSSSIEH.LSLN.qKSFYDS.............SYDPLQEDC..MGQFMTLNTSETSKIStlTFKES.....VVV.TVNG....KILK..KRR..LSFSQPITDEDLKVIASDP-VEE--lvv...............................................
A0A0M3KL74_CHLSB/1-72               ................................---------.......----....-.-.......--------------.--MK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPI..................................................
A0A287AFR7_PIG/1-39                 ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK..V-----.............---------..----------------..-----.....---.----....----..---..-------------------------rpyss.............................................
A0A2K6DC85_MACNE/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
A0A384CVD5_URSMA/1-105              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDV.............SYDPLHEDC..M----SLSTSETSKTSqlTFKEN.....VVV.VATN...gKILK..KRR..LSLNQFITDDDLEAITNDA-EEEI-m.................................................
A0A3Q7RVJ7_VULVU/1-101              ................................MAAVPELTS.......EMMA....Y.S.......SNNENDVFFEADGP.GNVK..CCCQDL.............NHSS----L..VDEGIQLQVSHQLCNK..SLRHF.....VSV.IVAL....EKLK..K--..-PCPQVLQGDDLKSIFRYIFEEEPI..................................................
A0A2K5NFE1_CERAT/16-86              ................................---------.......----....-.-.......--------------.----..------.............SYGPLHESC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSIADDNLEAIANDS-EEEII..................................................
A0A3P8SXI1_AMPPE/9-89               ....................lflkkmesemsc---------.......----....-.-.......--------------.----..------.............NMSEMWSQK..MPQGLDLEISDHPI--..TMRRV.....VNL.IIAM....ERLKagRSE..TVLSTDFRDENLLNIMLDSIVEEKI..................................................
A0A2K5ZAA3_MANLE/1-93               ................................MAEVPELAS.......EMMA....Y.Y.......---------RSVGT.--LR.qCSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
A0A287B6X4_PIG/1-101                ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A2K5BVG7_AOTNA/2-101              .............................fss---------.......---S....-.Y.......FDSENEEYSSSIDH.LSLN.qKSFYDV.............NYGSLHEEC..MDQSVSLNISETSKTSkfTFKES.....VVI.VSTN...gKVLK..KRR..LTLNQSITDDDLEAIANDI-EE---gk................................................
IL1B_HORSE/1-103                    ................................MAAVPD-TS.......DMMT....Y.C.......SGNENDLFFEEDGP.KQMK..GSFQDL.............DLSS----M..GDGGIQLQFSHHLYNK..TFKHA.....MSI.IVAV....EKLK..KIP..VPCSQAFQDDDLRSLFSVIFEEEPI..................................................
A0A2K5LYJ6_CERAT/1-93               ................................MAEVPELAS.......EMMA....Y.Y.......---------RSVGT.--LR.qCSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
A0A2K5BVQ1_AOTNA/1-103              ................................MAEVPELTS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..YSFQDL.............DLCP-----..MDGGIQLRLSRQHYSK..GFRQV.....VSV.VVAM....EKLR..KMP..VYCPQTFQDNDLSSFFPFIFEEEPI..................................................
A0A3M0IUH0_HIRRU/1-96               ................................MAFVPDLDT.......LESS....S.L.......---NEETFYGPNCP.CPQK..KPRLDL.............EVTS-----..PGVGIQVTVTKGHLSR..TFRQA.....AIL.VVAV....TKLL..KQ-..-PSHKDFADSDLGNFLDDIFE----pv................................................
A0A2K5VDE4_MACFA/35-137             ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
A0A3Q7UJN8_URSAR/30-133             ................................MARVPEPTS.......EMSY....Y.C.......SDNENDLFFEADGP.RKMK..CCFQDL.............NNSF----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPCSQLFQDDDLKNVFSCIFEEEPI..................................................
G3W4G1_SARHA/1-105                  ................................MAMVPEITC.......EEMD....F.Y.......RDNEH-QFYESDGP.NQKK..GNLQCL.............DLCPKESLL..VEDDIQLKFTAQPH--..QFYRT.....VVV.VVAI....EKMK..HLN..KICSQFFQDNDLMNIFTTIFQEEPI..................................................
A0A384BCQ4_BALAS/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDA.............SYEPLHEDC..MDKFISLNTSETSKTSklTFKEN.....VAK.VAAN...gKILK..KRR..LSLNQFITDDDLKDITNDT-EEEII..................................................
F7G8J2_MACMU/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
IL1A_MACFA/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEVSSSIDH.LSLN.qKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANDS-EEEII..................................................
A0A1S2ZW37_ERIEU/1-103              ................................MAAVPELAS.......EM-V....Y.Y.......SGNENDMLFEVDGP.KQMQ..CCFQDL.............DLSS----Q..GDDNIQLQISHQLYKK..KFRQV.....VSI.IVTV....EKLR..HML..VPDSQFSQNDDLKSLFHIIFEEEPI..................................................
A0A286ZMX3_PIG/1-100                ................................MATVPEPAK.......EVMN....N.G.......-DNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A2K6U6E7_SAIBB/1-103              ................................MAEVPELTS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..VDGGIQLRLSRQHDSK..GFRQV.....VSV.VMAM....EKLR..KMP..VYCPQTFQDNDLSTFFPFIFEEEPV..................................................
IL1A_MOUSE/1-111                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSAIDH.LSLN.qKSFYDA.............SYGSLHETC..TDQFVSLRTSETSKMSnfTFKES.....RVT.VSATssngKILK..KRR..LSFSETFTEDDLQSITHDL-EET--i.................................................
IL1A_HORSE/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLT.qKSFYDA.............SYDPLPEDC..MDTFMSLSTSETSKTSklNFKES.....VVL.VAAN...gKTLK..KRR..LSLNQFITNDDLEAIANDP-EEGII..................................................
G5B005_HETGA/1-111                  ................................MAEIPNLFE.......DLKS....C.Y.......--SENEEYASAIDH.LSLN.qKSFYDT.............SYGPLDKNC..MNTSMSLRTLETSEASelTFKKN.....LVV.VSTSa.hgTVLK..KRW..LSLNQTITNEDLDAIANDP-EEEII..................................................
A0A1S3FGQ2_DIPOR/1-111              ................................MAKVPDLFE.......DLKN....C.Y.......--SEGEEYSSAVDY.VSLN.qKSFYEA.............TYQPLNENC..MDKLMSQSTSETSKTSklTLNDG.....LVV.VAKSs.ngKILK..KRL..LSLNQTLTDDDLEAINNDE-KEEII..................................................
A0A3Q7S5W9_VULVU/1-105              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDM.............SCDPLHEDC..T----CLSTSEVSKTSqlTFKEN.....VVV.VAAN...gKILK..KRR..LSLSQFITDDDLEDIANDT--EEVIm.................................................
IL1B_CANLF/1-102                    ................................MAAVPELTS.......EMMA....Y.S.......SNNENDLFFEADGPgNDVK..CCCQDL.............NHSS----L..VDEGIQLQVSHQLCNK..SLRHF.....VSV.IVAL....EKLK..K--..-PCPQVLQEDDLKSIFCYIFEEEPI..................................................
R7VSW8_COLLI/1-96                   ................................MAFVPDLDT.......--LE....-.-.......SSSLNEETFYGPNC.LCLQ.kKPRLDL.............EAT-----S..PGVGIQVMATKGHPTR..TFRRA.....AVL.MVAI....SKLL..KR-..-PAHKDFADSDLGDFLDDIFE----pv................................................
IL1A_MACMU/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANDS-EEEII..................................................
H9H271_MELGA/44-121                 .....................hgsagcsaaal---------.......----....-.-.......--------------.----..-SLQKP.............RLDS---EH..TAVGVQVTVRKGRGAR..SFRQA.....AVL.VVAM....TKLL..RR-..-PTRRDFADSDLSALLEEVFE----pv................................................
H0YYU7_TAEGU/1-96                   ................................MAFVPDLDT.......L--E....-.-.......SSSLNEETFY--GP.NCLC.pQKKPRL.............DLEG---TS..PGVGIQVTVTKGPLSR..TFRQA.....AVL.VVAV....TKLL..KQ-..-PSRKDFADSDLGSFLDDIFE----pv................................................
A0A452SK07_URSAM/1-104              ................................MARVPEPTS.......EMSY....Y.C.......SDNENDLFFEADGP.RKMK..CCFQDL.............NNSF----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPCSQLFQDDDLKNVFSCIFEEEPI..................................................
IL1A_PIG/1-109                      ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSDIDH.LSLN.qKSFYDA.............SYEPLPGDG..MDKFMPLSTSKTSKTSrlNFKDS.....VVM.AAAN...gKILK..KRR..LSLNQFITDDDLEAIANDT-EEEII..................................................
IL1B_CAPHI/1-101                    ................................MATVPEPIN.......EVMA....Y.Y.......-SDENELLFEADGP.KQMK..SCTQHL.............DLGS----M..GDGNIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLR..SR-..-AYEHVFRDDDLRSILSFIFEEEPV..................................................
A0A1U7Q4M0_MESAU/1-111              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYNSAIDH.LSLS.qKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMSslTFEES.....LVM.VAATsdkgKILK..KRR..LGFNQAFAEDDLETITRNL-EET--i.................................................
A0A1U7TBU6_TARSY/1-103              ................................MATVPEPAS.......EMMD....Y.Y.......SSNEDDLFFEVDGP.KQMK..CSFQNL.............DVCP-----..LDEGIHLQISHQHHNK..SFRQI.....VSV.IVAV....EKLQ..KML..VPCPKAFQDNDLSALLSFIFEEEAI..................................................
G3QLV0_GORGO/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYHV.............TYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLEAIANDS-EEEII..................................................
F1MAF9_RAT/1-102                    ................................MAKVPDLFE.......DLKN....C.Y.......--R---ETESSFYH.LSLN.qKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILK..KRR..LSFNQPFTEDDLEAIAH--------..................................................
A0A2Y9E9G0_TRIMA/1-109              ................................MAKVPDLFE.......ELKD....C.Y.......--SENEEYSSNNNN.LSLN.qKSFYDA.............SYGPLQKVC..MDKYMSLSTSETSKTPkpTFKDS.....VAV.VTAR...gKILK..KRR..LSLHQLITNEDLEATANDL-EEEII..................................................
A0A218UCE5_9PASE/1-96               ................................MAFVPDLDT.......L--E....-.-.......SSSLNEETFY--GP.NCLC.pQKKPRL.............DLEG---TS..PGVGIQVTVTKGTLSR..TFHQA.....AVL.VVAV....TKLL..KQ-..-PSRKDFSDSDLGSFLDDIFE----pv................................................
IL1B_PIG/1-102                      ................................MAIVPEPAK.......EVMA....N.Y.......GDNNNDLLFEADGP.KEMK..CCTQNL.............DLGS----L..RNGSIQLQISHQLWNK..SIRQM.....VSV.IVAV....EKPM..KN-..-PSSQAFCDDDQKSIFSFIFEEEPI..................................................
IL1A_RAT/1-111                      ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSAIDH.LSLN.qKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILK..KRR..LSFNQPFTEDDLEAIAHDL-EET--i.................................................
H2QIK6_PANTR/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....VSV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
A0A402EJ04_9SAUR/34-139             ................................MARVPECQE.......EMME....F.C.......SLNEEIAFYEDQPC.LTKNasQSQRQC.............ASCSQIHCA..CGMDIQVKISKTVPTK..GFQKA.....VVI.VVAV....EKMK..LN-..-AKATVFTDDDLLNILNAV------lepv..............................................
F1LQB1_RAT/1-108                    ................................MAKVPDLFE.......DLKN....C.Y.......--R---ETESSFYH.LSLN.qKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILK..KRR..LSFNQPFTEDDLEAIAHDL-EET--i.................................................
A0A2R9AMR9_PANPA/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLEAIANDS-EEEII..................................................
A3DTN5_MELGA/1-94                   mafvpdldvlessslseetfygpsclclqkkp---------.......----....-.-.......--------------.----..------.............RLD---SEH..TAVGVQVTVRKGRGAR..SFRQA.....AVL.VVAM....TKLL..RR-..-PTRRDFADSDLSALLEEVFE----pv................................................
IL1B_RAT/1-102                      ................................MATVPELNC.......EIAA....F.-.......DSEENDLFFEADRP.QKIK..DCFQAL.............DLG-----C..PDESIQLQISQQHLDK..SFRKA.....VSL.IVAV....EKLW..QLP..MSCPWSFQDEDPSTFFSFIFEEEPV..................................................
A0A3Q1LXP9_BOVIN/1-108              ................................MAKVPDLFE.......DLKN....C.Y.......--REARHIRIQLGG.ICQG..KSFYDA.............SYEPLREDQ..MNKFMSLDTSETSKTSklSFKEN.....VVM.VAAS...gKILK..KRR..LSLNQFITDDDLEAIANNT-EEEII..................................................
A0A3Q2KRY5_HORSE/4-92               .......................eidsifhfp---------.......----....-.-.......--------------.-SSQ..KSFYDA.............SYDPLPEDC..MDTFMSLSTSETSKTSklNFKES.....VVL.VAAN...gKTLK..KRR..LSLNQFITNDDLEAIANDP-EEGII..................................................
A0A3Q7XCZ3_URSAR/4-103              .......................qnyiliilf---------.......----....-.-.......-NSENEEYSSEIDH.LSLN.qKSFYDV.............SYDPLHEDC..M----SLSTSETSKTSqlTFKEN.....VVV.VATN...gKILK..KRR..LSLNQFITDDDLEAITNDA-EEEI-m.................................................
F6RH14_CALJA/1-103                  ................................MAEVPELTS.......EMMT....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..VDGGIQLRLSRQHYSK..GFRQV.....VSV.VVAM....EKLR..RMP..VYCPQTFQDNDLSTFFPFIFEEEPI..................................................
A0A2C9F3A1_PIG/1-101                ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
F6X1Q9_XENTR/3-109                  ................................MALVPDLSS.......IPME....S.-.......-CSGDDEMFYSDSP.PGMK..DSMKDDs..........qwHSHPGHCSQ..YNLDIHLQITQAKGSL.qSFKKA.....VIL.VVAV....EKLK..R--..-GKETFFGDADLLGLLDSIFVEEEI..................................................
O73909_CHICK/1-94                   mafvpdldvlessslseetfygpsclclqkkp---------.......----....-.-.......--------------.----..------.............RLDS---EH..TTVDVQVTVRKGRGAR..SFRRA.....AVL.VVAM....TKLL..RR-..-PRSRDFADSDLSALLEEVFE----pv................................................
H9GZN1_HORSE/1-88                   ................................---------.......----....-.-.......SGNENDLFFEEDGP.KQMK..GSFQDL.............DLSS----M..GDGGIQLQFSHQLYNK..TFKHV.....VSI.IVAM....EKLK..KIP..VPCSQAFQDDDLRSLFSVIFEE---vv................................................
A0A2U3YMJ2_LEPWE/1-105              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDV.............SYDPLHEHC..M----CLSTSETSKTSqlIFKEN.....VVV.VAAN...gKVLK..KRR..LSLNQFIIDDDLEAITNDA-EEEI-m.................................................
Q32YM7_TRIMA/1-100                  ................................MATAPELNG.......DVMN....Y.Y.......SDNEDNLFFETDGP.KQMK..CCFQDL.............DLCS----P..GDGGIRLQISQQHHNR..SFKRV.....VSV.IVAV....EKLK..TIL..VPCSQSF----LTTIFSFIFEEEPI..................................................
L5KTV2_PTEAL/1-104                  ................................MAAVPELAS.......EAMA....Y.Y.......SGNENDLFFEADGP.TQTK..RPFHNL.............ELGS----L..GDSGIQLQVSPQLCST..SPGQV.....VSV.LVAL....EELR..AVP..TVCTQDLQEDDLRSLFFFIFEEEP-l.................................................
A0A2U3VWR1_ODORO/1-105              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDV.............SYDP----L..YEDCMSLSTSKTSKTSqlTFKEN.....VVV.VAAN...gKVLK..KRR..LSLNQFITDDDLDGFTNDA-EEEI-m.................................................
A0A287BRB4_PIG/1-105                ................................MATVPEPAK.......EVMQalcfY.Y.......SDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A2K5K1S5_COLAP/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYDPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLKAITSDS-EEEII..................................................
L9JLW9_TUPCH/1-103                  ................................MAVVPELAN.......EMMD....Y.Y.......SAEEDYLLFEADGP.KQTK..SFYQDV.............DFCS-----..PDKGIQLQISHQSYDK..SFKKF.....VSV.IVAV....EKLK..KTL..VPCPQDFQDIDLSILFSLIFDEKPI..................................................
U3JBA2_FICAL/1-96                   ................................MAFVPDLDT.......LESN....-.-.......--SLNEEMLY--GP.NCLC.pQKKPRL.............DLEV---TS..PGVGIQVTVTKGHLSR..TFRQA.....AVL.VAAV....TKLL..KQ-..-PSHNDFSDSDLGSFFDDIFE----pv................................................
A0A3Q1DAZ2_AMPOC/8-90               ...................dlffkkmesemsc---------.......----....-.-.......--------------.----..------.............NMSEMWSQK..MPQGLDLEISDHPI--..TMRRV.....VNL.IIAM....ERLKagRSE..TVLSTDFRDENLLNIMLESIVEEKIv.................................................
A0A1S3FFR2_DIPOR/1-102              ................................MAAVPELTS.......EMMA....Y.H.......-SDENDLFFETDGP.KQMK..CCLQDL.............DLCY-----..PDEGIQLQLSHQYFNK..SFRQV.....VSL.IVAV....EKLR..NKP..IPCSQAFQNDDLKTFFSIIFEEEP-m.................................................
A0A1U7T5G9_TARSY/1-110              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSTIDH.LSLN.qKSFYAG............iSYGELHEDY..TDHSMSLSTSETSKTSklTIKET.....VVR.VAAS...gKILK..KRR..LSLNQLITDDDLEAIANDS-EEEII..................................................
A0A2K6UJQ1_SAIBB/1-109              ................................MAKVPDLFE.......DLKD....C.Y.......--SENEEYSSSIDH.FSLN.qKSFYDV.............NYGSLHEEC..MDQSVSLNISETSKTSklIFKET.....VVI.VSTN...gKVLK..KRR..LSLNQSITDDDLEAIANDI-EEEII..................................................
A0A2I3HN27_NOMLE/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CPFQDL.............DLCP-----..LDGGIQLRISHQHYSK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLFPFIFEEEPI..................................................
A0A287AFR7_PIG/36-78                ............................pyss---------.......----....-.-.......--------------.----..------.............---------..----------------..--RPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A4D9DQQ0_9SAUR/1-102              ................................MAAVPDVQE.......ELME....F.C.......-SVNDEQFYEVNHP.YLGK..SSDQGP.............SPCSLHSAC..E-VGIQLQFTEQTSRK..VFRRS.....VVL.VVAI....EKMK..KA-..-LKARPFTDDDLMGIFDTVFE----ti................................................
IL1A_FELCA/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LTLN.qKSFYDA.............SYDPLHEDC..TDKFMSPSTSETSKTPqlTLKKS.....VVM.VAAN...gKILK..KRR..LSLNQFLTADDLEAIANEV-EEEI-m.................................................
IL1A_SHEEP/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLN.qKSFYDA.............SYEPLREDH..MNKFMSLDTSETSKTSrlSFKEN.....VVM.VTAN...gKILK..KRR..LSLNQFITDDDLEAIANDT-EEEII..................................................
IL1A_CERAT/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LFLN.qKSFYDV.............SYGPLHESC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSIADDNLEAIANDS-EEEII..................................................
G1LW58_AILME/1-105                  ................................MAKVPDLFE.......DLKN....C.C.......--SENEEYSSEIDH.LSLN.qKSFYDV.............SYDPLHEDC..M----SLSTSETSKTSqlTFKEN.....VVV.VATN...gKILK..KRR..LSLNQFITDDDLEAITNDA-EEEI-m.................................................
G1TXR4_RABIT/16-96                  ......................haptdclvsp---------.......----....-.-.......--------------.---Q..SCFQDL.............DLC-----C..PDEGIQLRISCQPYNK..SFRQV.....LSV.VVAL....EKLR..QKA..VPCPQAFQDDGLRTFFSLIFEEEPV..................................................
Q9TTK2_TURTR/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDA.............SYEPLHQDC..IDKYMSLNTPETSKTSklTFKEN.....VMM.VAAN...gKILK..NRW..LSLNQFLTDDDLEDIANDT-EEEII..................................................
IL1B_FELCA/1-103                    ................................MAPVPELTS.......EMMA....Y.Y.......-SDENDLFFEADGP.EKMK..GSLQNL.............SHSF----L..GDEGIQLQISHQPDNK..SLRHA.....VSV.IVAM....EKLK..KIS..FACSQPLQDEDLKSLFCCIFEEEPI..................................................
A0A3Q3LYR4_9TELE/12-96              ..........................gpfdye---------.......----....-.-.......----------AVEP.ESSC..SDMTDV.............EDAI---IK..LDDGLDLVVSHNPL--..TMQHM.....ATL.LLAV....KKMK..KSL..TRCRQELSDEELCSAIMDSLVEE--tav...............................................
A0A1S2ZW61_ERIEU/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SEDEVYSSEVDH.ISLN.qKSFYHA.............TYEPFHEKS..MDNFMSLSTFEISKTSnhTFKES.....TLM.VAAS...gKILK..KRR..FSLNQFLTDDDLEAIANDP-EEEII..................................................
B7ZSG9_XENLA/1-104                  ................................MALVPDLSS.......IPME....G.Y.......--SGDDEMFYSDSP.SGMK..DDMEDA.............AQWQSSTSH..CSLDIHVQITHGKGSL.hSFRKA.....VVL.VVAV....EKLK..R--..-GKERFFGDEDLLGLLDSIFVEEEI..................................................
A0A2U3VWQ9_ODORO/1-105              ................................MATVPEPTS.......EMMS....Y.Y......ySDNENDLFFEADGP.RKMK..CCFQDL.............NNSS----L..EDEGIQLHISHQLHNK..SLKHF.....VSV.VVAL....EKLK..KIS..LPCSQPLQDDDLKNIFCCIFEEEPI..................................................
A0A340WGC1_LIPVE/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDA.............SYEPLHEDC..MDKFMSLNTPETSKTSklTFKEN.....VVM.MAAK...gKILK..NRW..LSLNQFLTDDDLEDMANDT-EEEII..................................................
IL1B_RABIT/1-103                    ................................MATVPELTS.......EMMA....Y.H.......SGNENDLFFEADGP.NYMK..SCFQDL.............DLC-----C..PDEGIQLRISCQPYNK..SFRQV.....LSV.VVAL....EKLR..QKA..VPCPQAFQDDGLRTFFSLIFEEEPV..................................................
A0A2K5YIB2_MANLE/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDI.............SYGPLHEGC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSIADDNLEAIANDS-EEEII..................................................
A0A2Y9KXY7_ENHLU/1-105              ................................MARVPEPTS.......EVMS....YgY.......SDNENDLFFEADGP.GKMK..CCFQDL.............NNSY----L..EEEGIQLHISHQLHNK..SLSHF.....VSV.VVAL....EKLK..KIS..VPCSLPLQDDDLMNVFHCIFAEEPI..................................................
A0A0A0MPZ0_FELCA/36-138             ................................MAAVPELTS.......EMMA....Y.Y.......-SDENDLFFEADGP.EKMK..GSLQNL.............SHSF----L..GDEGIQLQISHQPDNK..SLRHA.....VSV.IVAM....EKLK..KIS..FPCSQPLQDEDLKSLFCCIFEEEPI..................................................
A0A3Q2H3V0_HORSE/1-103              ................................MAAVPKLTS.......ENTI....C.S.......-GNKNDLFFEAAGP.KQMK..ASFQDL.............DLSS----V..GNGAIMLHISQQLYNK..TFKHA.....ASI.IVAV....EKLK..KIP..IPCSQAFQDDDLRSLFSFIFEEEPI..................................................
A0A1V4KH82_PATFA/1-96               ................................MAFVPDLDT.......LE--....-.-.......SSSLTEETFYGPNC.LCLQ.kKPHLDL.............EVT-----S..PGVGIEVMATKGHPTG..TFRRA.....AVL.MVAV....TKLL..KR-..-PVHKDFADSDLGDFLDDIFE----pv................................................
B1AB80_HORSE/1-103                  ................................MAAVPD-TS.......DMMT....Y.C.......SGNENDLFFEEDGP.KQMK..GSFQDL.............DLSS----M..GDGGIQLQFSHQLYNK..TFKHV.....VSI.IVAM....EKLK..KIP..VPCSQAFQDDDLRSLFSVIFEEEPI..................................................
A0A2U3YM52_LEPWE/1-105              ................................MATVPEPTS.......EMMS....Y.Y......ySDKENDLFFEADGP.RKMK..CCFQDL.............NNSS----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPCSQPLRDDDLKNVFCCVFEEEPV..................................................
A0A2U3YM60_LEPWE/1-104              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDV.............SYDPLHEHC..M----CLSTSETSKTSqlIFKEN.....VVV.VAAN...gKVLK..KRR..LSLNQFIIDDDLEAITNDA-EE---vk................................................
Q712K7_ORNAN/1-117                  ................................MARVPDQSR.......DLME....C.Y.......SGDGEDQFYEVDGP.SQIK..SGFQDLkartcqetrihkeDKCS----P..CQMGIELKVTELPSSH..GFRKA.....VVL.VVAV....ERIK..RQA..VSYNTSFMDRDLMDIFTSIFKEEPI..................................................
A0A2K5NF39_CERAT/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYGPLHESC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSIADDNLEAIANDS-EEEII..................................................
A0A2Y9QBK0_DELLE/1-101              ................................MATVPEPTN.......EVMA....Y.Y.......-SDENDLLFEADGP.KQMK..CCVQPL.............DLNS----M..GDGSIHLQISHQLYNK..SLRRV.....VSV.IVAV....EKLQ..K--..IPCSQTFQDDGLRSIFSLIFEEEPV..................................................
F6SXC0_MONDO/1-114                  ................................MATVPEMAC.......DVMD....F.YsffgfvyRDNDDSQFYEADGP.NQKK.qGHLQYP.............DLCSKKCLL..EEDGIQLKFTAQSQ--..RFYRS.....VVV.VVAI....EKMR..HLV..ELSSGLFQDNDLMNIFTSIFQEEPI..................................................
A0A2K6DC97_MACNE/1-102              ................................MAEVPELAS.......EMMA....Y.Y.......-SSWQDHLTRFPPS.LSLQ..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
H2QIK5_PANTR/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLEAIANDS-EEEII..................................................
A0A384BCN2_BALAS/1-101              ................................MATVPEPTN.......EVMA....Y.Y.......-SDENDLLFEADGP.KQMK..CCVQHL.............DLSS----V..GDGSIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLK..R--..IPCSQAFQDDDLRSIFSLIFEEEPV..................................................
A0A151MMR4_ALLMI/1-92               .............................met---------.......----....-.C.......SMS-EECFYEADYP.STVK.gYSAAPL.............SPG---ESG..CGMNVQLQFTEPKTHR..GFRTT.....VVL.VVAV....EKMR..RM-..PQSPQLFSDCDLLNLFNAVFE----pvp...............................................
A0A2K6FGM6_PROCO/1-109              ................................MARVPDLFE.......DLKN....C.Y.......--SENEEYSSTIDH.LSLT.qKSFYDA.............SYSPHHKDY..MGQFMSLSTFETSKTSkfTFKES.....VVV.VADN...gKVLK..KRR..LSLNQHVTDDDLEAIANNS-EEGII..................................................
A0A2K5ZAB0_MANLE/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
A0A1A6HM55_NEOLE/1-102              ................................MATVPEFNS.......EMTA....F.H.......-SDDNDVFFEVDGP.QKMK..CCFQAA.............DLSY-----..PDESIQLQISQQHFNK..SFSQV.....VSL.IVAV....EKLW..NIP..VPCPWTFQDEDLRTFFSFIFEEEPI..................................................
A0A2R9BYV3_PANPA/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....VSV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
C9JWV2_HUMAN/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
IL1A_HUMAN/1-109                    ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLEAIANDS-EEEII..................................................
M7AWZ8_CHEMY/58-162                 ................................MAAVPDVQE.......ELME....F.C.......-SVNDEQFYEVDHP.YLGK..SSNQGS.............SPCSLSQSCsaCDLGIQLQFTEQTSPK..VFRRS.....VVL.VIAT....EKMK..KA-..-LKARPFTDDDLTGIFDTVFE----ti................................................
A0A287B6V6_PIG/35-106               ............................iypq---------.......----....-.-.......--------------.----..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A096NEW1_PAPAN/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNR..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
A0A0A0MPZ7_FELCA/1-100              ................................MAKVPDLFE.......DLKN....C.Y.......----------SFHV.PSSQ..KSFYDA.............SYDPLHEDC..TDKFMSPSTSETSKTPqlTLKKS.....VVM.VAAN...gKILK..KRR..LSLNQFLTADDLEAIANEV-EEEI-m.................................................
A0A0G2K003_RAT/1-109                ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYS--LDH.LSLN.qKSFYDA.............SYGSLHENC..TDKFVSLRTSETSKMStfTFKES.....RVV.VSATsnkgKILK..KRR..LSFNQPFTEDDLEAIAHDL-EET--i.................................................
IL1B_CAVPO/1-102                    ................................MAAVPELSS.......EVTA....Y.H.......-SDENELFFEVDGP.NKMQ..YCFQDR.............DLCS-----..LDEGIKLQISHQHFNK..SFRQT.....VSL.IVAV....EKLR..KKL..APCTWAFQDDDLRPLLPFIFEEEPI..................................................
A0A1A6HKM2_NEOLE/2-87               ............................eipl---------.......----....-.-.......--------------.-TKS..KSFYDA.............SYGSLHETC..TDKFISLRASETSRMSnfTFEES.....LVM.VAATsnqgKVLK..KRR..LGFNQAFAEDDLEAITHNL-EET--i.................................................
A0A2Y9FDJ9_PHYMC/1-101              ................................MAMVPEPAN.......EVMA....Y.Y.......-SDENDLLFEADGP.KQMK..CCVQHL.............DLSS----T..GDGSIQLQICHQLHDK..SFRQV.....VSV.IVAM....EKLK..R--..VPCSQAFQDDDLRGIFSVIFEEEPV..................................................
A0A091D3R2_FUKDA/1-101              ................................MAAVPEFSD.......EVTA....Y.H.......-SDENEMFFEIDGP.KQ-Q..YCFQDL.............DLCS-----..LDEGIELQISHQHFNK..SFRQV.....VSL.IVAV....KKLR..KEL..VPCPWTFQDNDLKTFFPFIFEEEPI..................................................
A0A140T838_BOVIN/1-101              ................................MATVPEPIN.......EMMA....Y.Y.......-SDENELLFEADGP.KQMK..SCIQHL.............DLGS----M..GDGNIQLQISHQFYNK..SFRQV.....VSV.IVAM....EKLR..NS-..-AYAHVFHDDDLRSILSFIFEEEPV..................................................
A0A2U4B015_TURTR/1-109              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDA.............SYEPLHQDC..IDKYMSLNTPETSKTSklTFKEN.....VMM.VAAN...gKILK..NRW..LSLNQFLTDDDLEDIANDT-EEEII..................................................
IL1B_HUMAN/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
G1LW44_AILME/1-104                  ................................MARVPEPTS.......EMSY....Y.C.......SDSENDLSFEADGP.SKMK..CCFQDL.............NSSF----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPSSQLFQDDDLKNVFSCIFEEEPI..................................................
A0A2K6R176_RHIRO/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KEMK..CSFQDL.............DLCP-----..LDGVIQLRISHEHYSK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLFPFIFEEEPI..................................................
A0A2K6MJJ0_RHIBE/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYDPLHEGC..MDQCVSLSISEISKTSklTFKQS.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLKAITSDS-EEEII..................................................
IL1A_CAVPO/1-107                    ................................-------FE.......DLKN....C.Y.......--SENEEYASAIDH.LSLN.qKSFYDT.............NYDPLHENR..VDEPVSPNPYENSEESnfTLEDSsdssaVVL.TSAH...gEVLK..KRR..LSLNQTMSNEDLEAIANDS-EEEII..................................................
IL1B_MUSPF/1-105                    ................................MARVPEPTS.......EVMS....YgY.......SDNENDLFFEADGP.GKMK..CCFQDL.............NNSY----L..EEEGIQLQISHQLHNK..SLSHF.....VSV.IVAL....EKLK..KIS..VPCSLPLQGDDLMNVFHCIFEEEPI..................................................
A0A2K6DDD6_MACNE/1-62               ................................---------.......----....-.-.......--------------.----..------.............---------..MDQSVSLSISEISKTSklTFKQS.....IVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANDS-EEEII..................................................
A0A087QNQ2_APTFO/1-96               ................................MAFVPDLDT.......--LE....-.-.......SSSLNEETFYDPDC.LYLQ.kKPCLDS.............EVTS-----..PGVGIQVTVTHGQPTR..TFRRA.....ATL.VVAV....TKLL..KQ-..-TMHKDFTDSDLGGFLDDIFE----pv................................................
A0A2K6NJ18_RHIRO/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYDPLHEGC..MDQCVSLSISEISKTSklTFKQS.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLKAITSDS-EEEII..................................................
M3YEA4_MUSPF/1-112                  ................................MAKVPDLFEdlqifkkDLKN....C.Y.......--SENEEYSSEIDH.LSLS.qKSFYDV.............NYDPLHEDC..M----SLRTSETSKTShlTFKED.....VVM.VAAS...gKILK..KRR..LSLNQFITDDDLEVITNDT-EEEI-m.................................................
A0A3P8SW69_AMPPE/2-76               .......................esemscnms---------.......----....-.-.......--------------.----..------.............---EMWSQK..MPQGLDLEISDHPI--..TMRRV.....VNL.IIAM....ERLKagRSE..TVLSTDFRDENLLNIMLDSIVEEKI..................................................
IL1A_BOVIN/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLN.qKSFYDA.............SYEPLREDQ..MNKFMSLDTSETSKTSklSFKEN.....VVM.VAAS...gKILK..KRR..LSLNQFITDDDLEAIANNT-EEEII..................................................
A0A2K5S6C4_CEBCA/1-62               ................................---------.......----....-.-.......--------------.----..------.............---------..MDQSVSLNISETSKTSklTFKES.....VVI.VSTN...gKVLK..KRR..LSLNQSITDDDLEAIANNI-EEEII..................................................
G3QU53_GORGO/1-103                  ................................MAEVPELTS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISHQHYSK..GFRQA.....VSV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
A0A226P217_COLVI/1-94               ................................MAFVPDLD-.......-VLE....S.N.......SLSEETFYSSACLC.LQKK..P-----.............RLDS---ER..TAMGMQVTVRKGHSAQ..SFRQA.....AEL.VVAM....TKLL..QR-..-PTRKDFADSDLSMLLEEVFE----pv................................................
G3SN89_LOXAF/1-109                  ................................MAKVPDLFE.......DLKD....C.Y.......--SENEEYSSNNDT.LSLI.qKSFYDA.............NYGPLQEVC..MDKFMSLSTSETSKIAkpAFKES.....VAV.VSAT...gKILK..KRR..LSLNQPITDEDLEAIANDP-EEEII..................................................
A0A2K5LYI4_CERAT/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
A0A2U3YM55_LEPWE/1-104              ................................MATVPEPTS.......EMMS....Y.Y.......YRSENDLFFEADGP.RKMK..CCFQDL.............NNSS----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPCSQPLRDDDLKNVFCCVFEEEPV..................................................
IL1B_SHEEP/1-101                    ................................MATVPEPIN.......EVMA....Y.Y.......-SDENELLFEVDGP.KQMK..SCTQHL.............DLGS----M..GDGNIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLR..SR-..-AYEHVFRDDDLRSILSFIFEEEPV..................................................
A0A2Y9S2F9_TRIMA/1-108              ................................MAKVPDLFE.......ELKD....C.Y.......--SENEEYSSNNNN.LSLN.qKSFYDA.............SYGPLQKVC..MDKYMSLSTSETSKTPkpTFKDS.....VAV.VTAR...gKILK..KRR..LSLHQLITNEDLEATANDL-EE---vk................................................
C9WPT5_CYNSE/2-76                   ..................esemkcsisemwlp---------.......----....-.-.......--------------.----..------.............--------T..MPKGLQLEISQHPM--..TMRQV.....VNL.VIAL....ERLKagRSE..SVMSTEFRDENLLSIMLDTIVEEQ-l.................................................
U3JBA1_FICAL/1-95                   ................................MAFVPDLDT.......LESN....-.-.......--SLNEEMLY--GP.NCLC.pQKKPRL.............DLEV---TS..PGVGIQVTVTKGHLSR..TFRQA.....AVL.VAAV....TKLL..KQ-..-PSHNDFSDSDLGSFFDDIF-----gm................................................
F6VT34_CALJA/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSSIDH.LSLN.qKSFYDV.............NYGSHHEEC..MDQSVSLSISETSKTSklTFKES.....VVI.VSTN...gKVLK..KRR..LTLNHSITDDDLEGITNDI-EEEII..................................................
A0A493SYV9_ANAPP/1-100              ................................MAFVPDL--.......DVLE....G.S.......--SLSEETFYGPDC.LYPP..KKLRLD.............SEAKHGQSR..TTVDVQVTVTPGDGAR..RFRQA.....ATL.VVAA....TKML..RR-..-PSHQDFADSDLGGFLEEIFE----pv................................................
A0A096NPG5_PAPAN/1-109              ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSIADDHLEAIANDS-EEEII..................................................
A0A2U3ZG75_ODORO/1-104              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDV.............SYDP----L..YEDCMSLSTSKTSKTSqlTFKEN.....VVV.VAAN...gKVLK..KRR..LSLNQFITDDDLDGFTNDA-EE---ak................................................
A0A2K5JR15_COLAP/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDHLFFEVDGP.KEMK..CSFQDL.............DLCP-----..LDGVIQLRISHEHYSK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLNTLFPFIFEEEPI..................................................
H0W1R8_CAVPO/1-114                  ................................MAQCPNMLE.......DLKS....C.Y.......--SENEEYASAIDH.LSLN.qKSFYDT.............NYDPLHENR..VDKPVSPNPYENSEESnfTLEDSsdssaVVL.TSAH...gEVLK..KRR..LSLNQTMSNEDLEAIANDS-EEEII..................................................
A0A3L8RU54_CHLGU/1-96               ................................MALVPDLDT.......--LE....-.-.......SSSLNEETFYGLNC.LCLQ.kKPRLDL.............EGTS-----..PGVGIQVTVTKGPLSR..TFRQA.....AIL.VVAV....TKLL..KQ-..-PSHKDFADSDLGSFLDDIFE----pv................................................
A0A2I3N9K4_PAPAN/1-93               ................................MAEVPELAS.......EMMA....Y.Y.......---------RSVGT.--LR.qCSFQDL.............DLCP-----..LDGGIQLQISHEHYNR..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
A0A2Y9KR26_ENHLU/1-112              ................................MAKVPDLFEdlqifkkDLKN....C.Y.......--SENEEYSSEIDH.LSLS.qKSFYDV.............NYDPLHEDC..M----SLRTSETSKTSqlTFKED.....VVM.VAAN...gKILK..KRR..LSLNQFITDDDLEVITNDT-EEEI-m.................................................
A0A2I3LTT5_PAPAN/1-101              ................................MAKVPDMFE.......DLKN....C.Y.......---------RCISC.DLMK..KSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklSFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSIADDHLEAIANDS-EEEII..................................................
Q9TTK1_TURTR/1-101                  ................................MATVPEPTN.......EVMA....Y.Y.......-SDENDLLFEADGP.KQMK..CCVQHL.............DLSS----T..GDESIHLQISHQLYNK..SFRHV.....VSV.IVAV....EKLQ..K--..IPCSQTFQDDGLRSIFSLIFEEEPV..................................................
A0A2K6L2N5_RHIBE/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KEMK..CSFQDL.............DLCP-----..LDGVIQLRISHEHYSK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLFPFIFEEEPI..................................................
G1NSN5_MYOLU/1-109                  ................................MAQVPDLFE.......DLKS....C.Y.......--SENEEYSSEIDQ.LSLN.qKSFYDA.............SYDPFPKNC..MGQFLSLSTSETSKTSqlTYKES.....VVV.VAAN...gKILK..KRR..LSFNQFITDDDLETIANDP-EEEI-l.................................................
IL1A_CAPHI/1-109                    ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLN.qKSFYDA.............SYGPLREDH..MNKFMSLDTSETSKTSrlSFKEN.....VVM.VTAN...gKILK..KRR..LSLNQFITDDDLEAIANDT-EEEII..................................................
IL1B_MACNE/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
A0A287AKL5_PIG/2-101                ......................cpgditeqal---------.......--CF....Y.Y.......SDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A452SK04_URSAM/1-97               ................................MARVPEPTS.......EMSY....Y.C.......-------RSVGRLR.PAMG..CCFQDL.............NNSF----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPCSQLFQDDDLKNVFSCIFEEEPI..................................................
G3I1B0_CRIGR/1-72                   ................................---------.......----....-.-.......--------------.--MK..CCFQSL.............DLSY-----..PDESIQLQITKQHHNK..SFRQV.....VSV.IVAV....EKLW..NIP..VAGPWTLQDEDLRTFFSFIFEEEPI..................................................
H2UVE3_TAKRU/1-76                   ..........................mesqmk---------.......----....-.-.......--------------.----..----SN.............ESK-MLQSQ..MPEGLELEITHHPL--..TMKSV.....VNL.VIAM....ERLK..GNRseSLLSTEFRDENLLSMMMDTIVEEQI..................................................
G3STJ8_LOXAF/1-100                  ................................MAAVPELFG.......DVRN....Y.Y.......SDNEDDLFFEPDGP.KQMK..CCFQDL.............DLCS----P..GDGGIRLQISQQHYNK..SFKQV.....VSV.IVAV....EKLK..TIL..VPCSQSF----LTNLFSFIFEEEPI..................................................
H2P5G1_PONAB/1-111                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFLSXx..........xxSYGPLHEGC..MDQSVSLSISETSKHP.gLLHES.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLQAIANGS-EEEII..................................................
A0A140T8E9_CANLF/1-105              ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDM.............SCDPLHEDC..M----SLSTSEISKTSqlTFKEN.....VVV.VAAN...gKILK..KRR..LSLSQFITDDDLEDIANDT--EEVIm.................................................
F7G8K0_MACMU/1-62                   ................................---------.......----....-.-.......--------------.----..------.............---------..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANDS-EEEII..................................................
I3M051_ICTTR/1-88                   ................................MAAVPELAS.......EMMA....Y.H.......-SDENDLFFEVDGP.KHMK..PIFCDP.............---------..----------------..-----.....---.----....----..---..-------------------------wdddgyeydaavpvlncrlrdvqqkslvlsdpcelkalhlngpnlrqqvv
G1QMS9_NOMLE/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYHV.............SYGPLHEGC..MDQSVSLSISETSKTSklTFKES.....MVV.VATN...gKVLK..KRR..LSLSQSITDDDLEAITNDS-EEEII..................................................
F7C3T8_HORSE/1-109                  ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLT.qKSFYDA.............SYDPLPEDC..MDTFMSLSTSETSKTSklNFKES.....VVL.VAAN...gKTLK..KRR..LSLNQFITNDDLEAIANDP-EEGII..................................................
H2P5G2_PONAB/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISHQHYSK..GFKQA.....VSV.VVAM....DKLR..KML..VPCPQNFQDNDLSTFFPFIFEEEPI..................................................
C9JVK0_HUMAN/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
A0T125_CANLF/1-95                   ................................MAKVPDLFE.......DLKN....C.Y.......--SENEEYSSEIDH.LSLN.qKSFYDM.............SCDPLHEDC..M----SLSTSEISKTSqlTFKEN.....VVV.VAAN...gKILK..KRR..LSLSQFITDDDLE------------d.................................................
G7PMZ6_MACFA/1-109                  ................................MAKVPDMFE.......DLKN....C.Y.......--SENEEDSSSIDH.LSLN.qKSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANDS-EEEII..................................................
A0A452SK66_URSAM/16-82              ...............................s---------.......----....-.-.......--------------.----..------.............-YDPLHEDC..M----SLSTSETSKTSqlTFKEN.....VVV.VATN...gKILK..KRR..LSLNQFITDDDLEAITNDA-EEEI-m.................................................
A0A3Q0FJI4_ALLSI/1-89               ................................MAEVPDFLA.......DQME....T.C.......SMSEE-CFYEADYH.STVK.gY--SAA.............PLSP-EESG..CGLNVQLQFTEPKTHR..GFRTT.....VVL.VGAV....EKMR..RMP..Q------------------------spqlfsxx..........................................
A0A0D9RW29_CHLSB/1-62               ................................---------.......----....-.-.......--------------.----..------.............---------..MDQSVSLSIYEISKTSklTFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANNS-EEEII..................................................
A7Y3X8_CAPHI/1-101                  ................................MATVPEPIN.......EVMA....Y.Y.......-SDENELLFEADGP.KQMK..SCTQHL.............DLGS----M..GDGNIQLQISHQLYNK..SFRQV.....VSV.IVAM....EKLR..SR-..-AYEHVFRDDDLRSILSFIFEEEPV..................................................
H0WRY2_OTOGA/1-104                  ................................MARVPDLFE.......D---....Y.Y.......--SENEEHSSAFDQ.LCLN.qKSFYDA.............SHSSHNKDC..VDQFMCLSACETSKGSgcTVQES.....VVL.VTAK...gKVLK..KRR..FNLDQSITDDDLEAIPHDK-K----ev................................................
A0A2K5VBY6_MACFA/1-101              ................................MAKVPDMFE.......DLKN....C.Y.......------RFIS---C.DLMK..KSFYDV.............SYGPLHEGC..MDQSVSLSISEISKTSklTFKQS.....MVV.VSTN...gKVLK..KRR..LSLSQSITDNNLEAIANDS-EEEII..................................................
A0A384CV32_URSMA/1-104              ................................MARVPEPTS.......EMSY....Y.C.......SDNENDLFFEADGP.RKMK..CCFQDL.............NNSF----L..EDEGIQLHISHQLQNK..SLRHF.....VSV.VVAL....EKLK..KIS..LPCSQLFQDDDLKNVFSCIFEEEPI..................................................
A0A2K6FAZ1_PROCO/1-103              ................................MAAVPEPAS.......EMMA....Y.Y.......SGNEDDLFFEVDGP.KQMK..CSFQDT.............DLC-----L..SDGGIQLHVSHQHYNK..SFGQV.....VSL.IVAV....EKLR..NKP..VLCPKAFQEDDLSTFFPFIFEEEPI..................................................
F1SUB9_PIG/1-101                    ................................MATVPEPAK.......EVMA....N.N.......GDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
C9JSC2_HUMAN/1-103                  ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFEADGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLRISDHHYSK..GFRQA.....ASV.VVAM....DKLR..KML..VPCPQTFQENDLSTFFPFIFEEEPI..................................................
IL1B_MACMU/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK..CSFQDL.............DLCP-----..LGGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
A0A287A4B5_PIG/3-100                ........................gditeqal---------.......--CF....Y.Y.......SDNNNDLLFEADGP.KEMK..CRTQNL.............DLSP----L..GDGSIQLQISHQLCNE..SSRPM.....VSV.IVAK....EKPM..N--..-PSSQVVCDDDPKSIFSSVFEEEPI..................................................
A0A2Y9RYF7_TRIMA/1-100              ................................MAAAPELNG.......DVMN....Y.Y.......SDNEDNLFFETDGP.KQMK..CCFQDL.............DLCS----P..GDGGIRLQISQQHHNR..SFKRV.....VSV.IVAV....EKLK..TIL..VPCSQSF----LTTIFSFIFEEEPI..................................................
W5QI89_SHEEP/42-150                 ................................MAKVPDLFE.......DLKN....C.Y.......--SENEDYSSEIDH.LSLN.qKSFYDA.............SYEPLREDH..MNKFMSLDTSETSKTSrlSFKEN.....VVM.MTAN...gKILK..KRR..LSLNQFITDDDLEAIANDT-EEEII..................................................
A0A2K5VDC7_MACFA/1-103              ................................MAEVPELAS.......EMMA....Y.Y.......SGNEDDLFFDVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNE..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQIFQDNDLSTLIPFIFEEEPV..................................................
G5B006_HETGA/35-136                 ................................MAAVPEFSN.......EVTA....Y.H.......-SDENEMFFEVDGP.KQMK..HCFQDL.............DLCS-----..LDEGIELQISHQHFKK..SFQQV.....VSL.IVAV....EKLR..KEL..VPCPWTFQDNDLRTFFPFIFEEEPI..................................................
IL1B_CERAT/1-103                    ................................MAEVPELAS.......EMMA....Y.Y.......SSNEDDLFFEVDGP.KQMK..CSFQDL.............DLCP-----..LDGGIQLQISHEHYNK..GFRQA.....VSV.VVAM....EKLR..KML..VPCPQTFQDNDLSTLIPFIFEEEPV..................................................
H0WRY4_OTOGA/1-103                  ................................MAAVPELTS.......EMMD....Y.Y.......SGNEDDLFFEAEGS.KQMK..CSFQDL.............DLCP-----..TDGGIQLHVSHQHYNK..DFRQV.....VSL.IVAM....EKLR..NKP..VLCPKAFQDGDLSTFFPFIFEEEPI..................................................
#=GC seq_cons                       ................................MApVP-hhp.......-hhs....h.Y.........sEs-.h.ps.s..hphp..psF.Dl.............shss....h..hDtulpLplScpphsp..oF+ps.....VsV.VsAh....c+L+..Kh...lshsQshpD-DLcslhstl.EEE.l..................................................
//
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