GenomeNet

Database: Pfam
Entry: IL2
LinkDB: IL2
Original site: IL2 
#=GF ID   IL2
#=GF AC   PF00715.18
#=GF DE   Interleukin 2
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_709 (release 2.1)
#=GF GA   26.20 26.20;
#=GF TC   80.00 53.40;
#=GF NC   25.00 21.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Interleukin
#=GF DR   INTERPRO; IPR000779;
#=GF DR   SCOP; 3ink; fa;
#=GF DC   This family is a subset of the SCOP family.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF SQ   88
#=GS A0A2K6TDD1_SAIBB/7-151   AC A0A2K6TDD1.1
#=GS G1PJ32_MYOLU/7-147       AC G1PJ32.1
#=GS A0A096MT93_PAPAN/7-151   AC A0A096MT93.1
#=GS A0A091E2M5_FUKDA/7-131   AC A0A091E2M5.1
#=GS IL2_CAPHI/7-152          AC P36835.1
#=GS A0A1A6GQH7_NEOLE/1-93    AC A0A1A6GQH7.1
#=GS IL2_HORSE/7-146          AC P37997.2
#=GS A0A1S3FNJ6_DIPOR/7-150   AC A0A1S3FNJ6.1
#=GS A0A2Y9F6D3_PHYMC/7-151   AC A0A2Y9F6D3.1
#=GS IL2_BOVIN/7-152          AC P05016.1
#=GS H0VBY4_CAVPO/7-149       AC H0VBY4.1
#=GS IL2_RABIT/7-149          AC O77620.1
#=GS A0A383ZBN1_BALAS/7-151   AC A0A383ZBN1.1
#=GS A0A2U3V619_TURTR/7-151   AC A0A2U3V619.1
#=GS A0A2K6A5J1_MANLE/7-151   AC A0A2K6A5J1.1
#=GS IL2_DELLE/7-151          AC Q9XT84.1
#=GS G1RE34_NOMLE/7-150       AC G1RE34.1
#=GS A0A2Y9Q9K4_DELLE/7-151   AC A0A2Y9Q9K4.1
#=GS A0A2R9AGA9_PANPA/48-130  AC A0A2R9AGA9.1
#=GS A3FBE6_MUSPF/7-149       AC A3FBE6.1
#=GS A3FBE6_MUSPF/7-149       DR PDB; 4ZF7 B; 6-129;
#=GS A3FBE6_MUSPF/7-149       DR PDB; 4ZF7 A; 5-129;
#=GS G3SU90_LOXAF/7-147       AC G3SU90.1
#=GS G8JKZ2_BOVIN/9-154       AC G8JKZ2.1
#=GS IL2_PIG/7-151            AC P26891.1
#=GS A0A2K6MRS3_RHIBE/1-132   AC A0A2K6MRS3.1
#=GS G3HTL8_CRIGR/7-151       AC G3HTL8.1
#=GS A0A2I2Y7Q8_GORGO/1-131   AC A0A2I2Y7Q8.1
#=GS A0A2K6MRS2_RHIBE/7-151   AC A0A2K6MRS2.1
#=GS A0A2K5VAW2_MACFA/7-151   AC A0A2K5VAW2.1
#=GS A0A2I3T915_PANTR/1-131   AC A0A2I3T915.1
#=GS A0A2U3Y3E4_LEPWE/7-151   AC A0A2U3Y3E4.1
#=GS A0A2Y9E495_TRIMA/31-171  AC A0A2Y9E495.1
#=GS Q5QT37_CAPHI/7-152       AC Q5QT37.1
#=GS L5K7D9_PTEAL/7-149       AC L5K7D9.1
#=GS A0A2K5MA77_CERAT/1-132   AC A0A2K5MA77.1
#=GS A0A2R9AGA9_PANPA/7-50    AC A0A2R9AGA9.1
#=GS A0A1S3AKL6_ERIEU/7-146   AC A0A1S3AKL6.1
#=GS H2PE89_PONAB/7-150       AC H2PE89.1
#=GS B1AB81_HORSE/7-146       AC B1AB81.1
#=GS IL2_MACMU/7-151          AC P68291.1
#=GS L9KIU7_TUPCH/48-130      AC L9KIU7.1
#=GS A0A0D9QUJ6_CHLSB/7-151   AC A0A0D9QUJ6.1
#=GS IL2_MOUSE/7-165          AC P04351.1
#=GS IL2_MOUSE/7-165          DR PDB; 4YUE C; 27-145;
#=GS IL2_MOUSE/7-165          DR PDB; 4YQX A; 27-145;
#=GS IL2_MOUSE/7-165          DR PDB; 4YQX M; 27-145;
#=GS IL2_CERAT/7-151          AC P46649.1
#=GS IL2_SHEEP/7-152          AC P19114.2
#=GS L9KIU7_TUPCH/7-50        AC L9KIU7.1
#=GS A0A3Q7WXD6_URSAR/7-152   AC A0A3Q7WXD6.1
#=GS A0A2K6NXW2_RHIRO/7-151   AC A0A2K6NXW2.1
#=GS IL2_RAT/7-151            AC P17108.1
#=GS A0A1U7U2W1_TARSY/7-150   AC A0A1U7U2W1.1
#=GS G5C793_HETGA/7-149       AC G5C793.1
#=GS A0A340XUF4_LIPVE/7-151   AC A0A340XUF4.1
#=GS IL2_PAPAN/7-151          AC Q865Y1.1
#=GS A0A384BYP6_URSMA/7-152   AC A0A384BYP6.1
#=GS A0A2K6ALW7_MACNE/1-132   AC A0A2K6ALW7.1
#=GS A0A2U3W0Y7_ODORO/7-152   AC A0A2U3W0Y7.1
#=GS A0A2R9ABF1_PANPA/1-131   AC A0A2R9ABF1.1
#=GS IL2_MACFA/7-151          AC Q29615.1
#=GS G3S1Y8_GORGO/7-150       AC G3S1Y8.1
#=GS IL2_CANLF/7-152          AC Q29416.1
#=GS A0A1D5RGK2_MACMU/1-132   AC A0A1D5RGK2.1
#=GS B3VBJ5_MESAU/7-151       AC B3VBJ5.1
#=GS A0A2R9ACE1_PANPA/7-150   AC A0A2R9ACE1.1
#=GS A4GT77_VULVU/7-152       AC A4GT77.1
#=GS A0A2Y9KGA6_ENHLU/7-152   AC A0A2Y9KGA6.1
#=GS A0A452SAK8_URSAM/7-152   AC A0A452SAK8.1
#=GS A0A2K6GXC5_PROCO/7-149   AC A0A2K6GXC5.1
#=GS A0A2K6A5K1_MANLE/1-132   AC A0A2K6A5K1.1
#=GS H2QQ44_PANTR/7-150       AC H2QQ44.1
#=GS A0A2K6NXV7_RHIRO/1-132   AC A0A2K6NXV7.1
#=GS A0A2K5J7D7_COLAP/7-151   AC A0A2K5J7D7.1
#=GS H0Y254_OTOGA/7-149       AC H0Y254.1
#=GS A0A2I3G971_NOMLE/3-129   AC A0A2I3G971.1
#=GS G3VGM5_SARHA/7-137       AC G3VGM5.1
#=GS A0A2I3MT18_PAPAN/1-132   AC A0A2I3MT18.1
#=GS IL2_HUMAN/7-150          AC P60568.1
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ M; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 2B5I A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1Z92 A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 2ERJ H; 3-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 F; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1NBP A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ P; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1PY2 C; 7-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1IRL A; 1-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ b; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 E; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ Y; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 5UTZ I; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1PY2 B; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1QVN A; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 G; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 4NEJ A; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ S; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ V; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 H; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 5UTZ D; 5-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ D; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ h; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3INK C; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M49 A; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M47 A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 5UTZ E; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ G; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1QVN B; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ J; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 4NEM A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M4B A; 5-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M48 A; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 D; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1QVN D; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1PY2 D; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3INK D; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ e; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 C; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M4C A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1PW6 B; 5-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M49 B; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 2ERJ D; 3-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1PY2 A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M48 B; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 5M5E D; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1QVN C; 4-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M4A A; 7-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 B; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1M4C B; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 5LQB A; 26-150;
#=GS IL2_HUMAN/7-150          DR PDB; 3QAZ A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 1PW6 A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 3QB1 A; 6-130;
#=GS IL2_HUMAN/7-150          DR PDB; 5UTZ A; 1-130;
#=GS IL2_FELCA/7-151          AC Q07885.1
#=GS W5NPD0_SHEEP/7-158       AC W5NPD0.1
#=GS Q0PIT4_CALJA/7-151       AC Q0PIT4.1
#=GS A0A2K5J7H7_COLAP/1-132   AC A0A2K5J7H7.1
#=GS A0A2K5VAX1_MACFA/1-132   AC A0A2K5VAX1.1
#=GS I3MQX6_ICTTR/7-151       AC I3MQX6.1
#=GS IL2_VULVU/7-152          AC Q25BC3.1
#=GS IL2_AILME/7-152          AC Q5PXD0.1
#=GS A0A2K5MA48_CERAT/7-151   AC A0A2K5MA48.1
#=GS G3VGM6_SARHA/7-137       AC G3VGM6.1
#=GS IL2_MACNE/7-151          AC P68290.1
#=GS IL2_AOTNA/7-151          AC Q7JFM5.1
#=GS A0A2K5QJC8_CEBCA/7-151   AC A0A2K5QJC8.1
A0A2K6TDD1_SAIBB/7-151              ..LSCIALSLALITNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMLLNGINNYKNPKLTRMLTFKFYLPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTRDIISNI......NVLVLELKGSETTFTCEYDDDTATIIEFLNGWITFCQSIIS..............
G1PJ32_MYOLU/7-147                  ..LSCIALTLAFIADGAP.T.SSS.S..............QETQQQLEHLILDMQRLLNGVSNYKNSKLPMMLTFKFYMPR.NATELKHLQCLVDELKPLEEVLKLEKS----LSNITELMSNV......NVLVQNLKGPKTRFECDYDDETVTIVEFLNKWITFCQRIFS..............
A0A096MT93_PAPAN/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A091E2M5_FUKDA/7-131              ..LSCIALTLALITSSAP.T.SSS.T..............RETQEQLEQLLLDLQVIWDGVT--RNPKISKMLKPKLYFPN.KPSELRHLQCLEEELKPLEQVLNLAEHKHFPLINTKDFISNI......NVTVKKLKI--------------------------------eityqqsaallvaq
IL2_CAPHI/7-152                     ..LSCIALTLALVANGAP.T.SSS.T..............GNTMKEVKSLLLDLQLLLEKVKNLENLKLSRMHTFNFYMPKvNDTELKHLKCLLEELKLLEDVLDLAPSKNRNTREIKDYMASL......KGIVLELQGSETRFTCEYDDATVKAVEFQNKWTTFCQSIYS..............
A0A1A6GQH7_NEOLE/1-93               ..----------------.-.---.-..............-------------------------------MLTFKFYMPK.KATDLKHLQCLEEELGALQHVLDLAQSKSFRLEDAENSISNI......RVTVMKLKGSENTSMCEFHDETVTVMEFLRRWITFCQSII-e.............
IL2_HORSE/7-146                     ..LSCIALTLAVLANSAP.T.SSS.K..............RETQQQLKQLQMDLKLLLEGVNNNKNPKLSKILTFKINMPK.KATELKHLQCLEEELKPLEEML-----KNFLSKDIKELMSNI......NVTVLGLKGSETRFTCEYDNETETIVEFLNKWITFCQSIIS..............
A0A1S3FNJ6_DIPOR/7-150              .l-LCIALGLVLVINSAP.T.SAP.M..............KEARGQLEQVLLDLQVLLKAVNSDKNLKLSRMLTFKFYMPK.KATDLKHLQCLEEELKPLEGVLNLAQSNNFHLKDSRDLISNI......NVTVLKLKGSET-FICDYEDKTATIVEFLNRWIIFCQGIIS..............
A0A2Y9F6D3_PHYMC/7-151              ..LSCIALTLALVANGAP.T.SSS.T..............ENTKEQVKSLLLDLRLLSNEVNNYENLKLFRMLTFKFYMPK.KATELKHLQCLAEELKPLEDVLNVAQSKTQNWTGIKDLMDNI......NRIVLTLKGSETRFTCEYDDETVTAVEFLEKWITFCQSIYS..............
IL2_BOVIN/7-152                     ..LSCIALTLALVANGAP.T.SSS.T..............GNTMKEVKSLLLDLQLLLEKVKNPENLKLSRMHTFDFYVPKvNATELKHLKCLLEELKLLEEVLNLAPSKNLNPREIKDSMDNI......KRIVLELQGSETRFTCEYDDATVNAVEFLNKWITFCQSIYS..............
H0VBY4_CAVPO/7-149                  ..LSCLALTLALLTSSAP.T.SSS.P..............KQTQDRLELLLRDLQTLLEGVT--SNPRLPKMLKLKLYPPK.MVSELQHLQCLEEELRAVEQVLNLAEHKNFPLIHTKDFISNI......NVTVLSLKGSETAFVCDLEDESVNIVEFLKRWIAFCQKIMS..............
IL2_RABIT/7-149                     ..LSCIALTLALLTSSAP.T.SSS.T..............KETQEQLDQLLLDLQVLLKGVNDYKNSKLSRMLTFKFYMPK.KVTELKHLQCLEEELKPLEEVLNLAQGKNSHGGNTRESISNI......NVTVLKLKGSET-FMCEYD-ETVTIVEFLNRWITFCQSIIS..............
A0A383ZBN1_BALAS/7-151              ..LSCIALTLALVANGAP.T.SSS.T..............ENTKEQVKSLLLDLQLLLKEINNYENLKLFRMPTFKFYMPK.KATELKHLQCLAEELKPLEDVLNAAQSKIQNSIDIKDLMDNI......NRIVLTLKGSETRFTCEYDDETVTAVEFLKKWITFCQSIYS..............
A0A2U3V619_TURTR/7-151              ..LSCIALTLALVANGAP.T.SSS.T..............ENTKKQVQSLLQDLHLLLKEINNYENLKLFRMLTFKFYMPK.KATELKHLQCLAEELKPLEDVLNVAQSKTQNSIDIKDLMDNI......NRIVLTLKGSETRFTCEYDDETVTAVELLNKWITFCQSIYS..............
A0A2K6A5J1_MANLE/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_DELLE/7-151                     ..LSCIALTLALVANGAP.T.SSS.T..............ENTKKQVQSLLQDLHLLLKEINNHENLKLFRMLAFKFYMPK.KATELKHLQCLAEELKPLEDVLNVAQSKTQNSIDIKDLMDNI......NRIVLTLKGSETRFTCEYDDETVTAVEFLNKWITFCQSIYS..............
G1RE34_NOMLE/7-150                  ..LSCIALSLALVTNGAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVQELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2Y9Q9K4_DELLE/7-151              ..LSCIALTLALVANGAP.T.SSS.T..............ENTKKQVQSLLQDLHLLLKEINNYENLKLFRMLTFKFYMPK.KATELKHLQCLAEELKPLEDVLNVAQSKTQNSIDIKDLMDNI......NRIVLTLKGSETRFTCEYDDETVTAVEFLNKWITFCQSIYS..............
A0A2R9AGA9_PANPA/48-130             .i----------------.-.---.-..............-----------------------------------------.NATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
A3FBE6_MUSPF/7-149                  ..LSCIVLTLALFANSAP.TtSSS.T..............KEAQQQLEQLLLDLQLLLNGVKNYES---PRMLTFKFYMPK.KATELTHLQCLAEELKLLEEVLYLAQSKNFHLTDIKELMSNI......NVTLLKLKGSETSFKCEYDDETVTITEFLNKWITFCQSIFS..............
#=GR A3FBE6_MUSPF/7-149       SS    ..XXXXXXXXXXXXXXXX.XX-HH.H..............HHHHHHHHHHHHHHHHHHHHHHCCC----GGGGG--EEEEC.---SGGGHHHHHHHHHHHHHHHHHCC-TTGGHCHHHHHHHHH......HHHHHHH--S-S----EEECCEE-HHHHHHHHHHHHHHHHC..............
G3SU90_LOXAF/7-147                  ..LSCIALTLALVANSAP.T.SSS.T..............KETQQQLEQLLLDLQMLLIRVKNYETRRLSMIFTFKFNMPK.EVTELKHLQCLVDELKPLEDVLNVAPSK----QNTRELISNI......NVTALELQGSETTFMCEYDDHAATIEEFLNKWIVFCQSIIS..............
G8JKZ2_BOVIN/9-154                  ..LSCIALTLALVANGAP.T.SSS.T..............GNTMKEVKSLLLDLQLLLEKVKNPENLKLSRMHTFDFYVPKvNATELKHLKCLLEELKLLEEVLNLAPSKNLNPREIKDSMDNI......KRIVLELQGSETRFTCEYDDATVNAVEFLNKWITFCQSIYS..............
IL2_PIG/7-151                       ..LCCIALTLALMANGAP.T.SSS.T..............KNTKKQLEPLLLDLQLLLKEVKNYENADLSRMLTFKFYMPK.QATELKHLQCLVEELKALEGVLNLGQSKNSDSANIKESMNNI......NVTVLELKGSETSFKCEYDDETVTAVEFLNKWITFCQSIYS..............
A0A2K6MRS3_RHIBE/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
G3HTL8_CRIGR/7-151                  ..ASCLALTLALLVNSAP.T.SSS.K..............KETQQHLEQLLLDLQVLLKGINNNKNPKLPMMLTFKFYMPK.KATELKHLQCLEEELGALQSVLDLAQSKSFQLEDTENFISNI......RVTVVKLKGSENTFTCEFDDETVTVVEFLSRWITFCQSII-a.............
A0A2I2Y7Q8_GORGO/1-131              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2K6MRS2_RHIBE/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2K5VAW2_MACFA/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2I3T915_PANTR/1-131              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2U3Y3E4_LEPWE/7-151              ..LSCIALTLVLVANSAP.T.TSS.T..............KETQQQLEQLLLDLRLLLNGVNNYEDPKLSRMLTFKFYTPK.KATELTHLQCLAEELKLLEEVLYLAQSKNFHLTDIKELMSNI......NVTLLKLKGSETRFKCEYDDETATITEFLNKWITFCQSIFS..............
A0A2Y9E495_TRIMA/31-171             ..LSCIVLTLALITNSAP.T.SSS.A..............KETQQQLEQLLLDLRMLLVRVKNYEPRRLSMMFTFKFNMPK.KATELKHLQCLVEELKPLEDVLNVAPSK----QNTRELISNI......NVTALELQGSKTPFMCEYDDKAATIEEFLNNWIAFCQRIIS..............
Q5QT37_CAPHI/7-152                  ..LSCIALTLALVANGAP.T.SSS.T..............GNTMKEVKSLLLDLQLLLEKVKNPENLKLSRMHTFNFYMPKvNATELKHLKCLLEELKLLEEVLDLAPSKNLNTREIKDSMDNI......KRIVLELQGSETRFTCEYDDATVKAVEFLNKWITFCQSIYS..............
L5K7D9_PTEAL/7-149                  ..LSCIALTLALVADGAP.T.SSS.R..............KETQQQLEHLLKDLQRLLETVNNYKNHELSSMLTFKFYMP-.NATELNHLQCLVDELKPLEEVLTIAQSKNSH-SDIKESVSNI......NVTAQKLKGPETKYTCVYNDESANVKEFLNKWITFCQSILS..............
A0A2K5MA77_CERAT/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2R9AGA9_PANPA/7-50               ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGIN-------------------.------------------------------------------......-----------------------------------------a.............
A0A1S3AKL6_ERIEU/7-146              ..LVCSVLALALLACSVP.T.ARL.A..............RDSEQHLEQLLLDLKKLKLGVENHKGSTLATMLRFPFYLPK.EATELKHFQCLVGELKPLGEVLSLAEC-----RHISELMSNI......NATVLELKGSGPTLPCDYEEEAVSVLQLLAKWISICQSIYS..............
H2PE89_PONAB/7-150                  ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
B1AB81_HORSE/7-146                  ..LACIALTLAVLANSAP.T.SSS.K..............RETQQQLKQLQMDLKLLLEGVNNNKNPKLSKMLTFKINMPK.KATELKHLQCLEEELKPLEEML-----KNFLSKDIKELMSNI......NVTVLGLKGSETRFTCEYDDETGTIVEFLNKWITFCQSIFS..............
IL2_MACMU/7-151                     ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
L9KIU7_TUPCH/48-130                 .i----------------.-.---.-..............-----------------------------------------.NATELKHLQCLEEELKPLEKVLNLAQSKNFHLKDTRQLISNI......NVTVLELKGSETS-VCEYEDRVATIVEFLNMWITFCQSIIS..............
A0A0D9QUJ6_CHLSB/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_MOUSE/7-165                     ..ASCVTLTLVLLVNSAP.T.SSS.TssstaeaqqqqqqqQQQQQHLEQLLMDLQELLSRMENYRNLKLPRMLTFKFYLPK.QATELKDLQCLEDELGPLRHVLDLTQSKSFQLEDAENFISNI......RVTVVKLKGSDNTFECQFDDESATVVDFLRRWIAFCQSIIS..............
#=GR IL2_MOUSE/7-165          SS    ..XXXXXXXXXXXXXXXX.X.XXX.XXXXXXXXXXXXXXXXXXXXHHHHHHHHHHHHHHHHHHBTT--HHHHTCEEEE-BS.S--SGGGHHHHHHTHHHHHHHHHHHHHHSS--TTHHHHHHHH......HHHHHHHT-SSS-----B-EEEEEHHHHHHHHHHHHHHHHH..............
IL2_CERAT/7-151                     ..LSCIALSLALVTNSAP.T.SRS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_SHEEP/7-152                     ..LSCIALTLALVANGAP.T.SSS.T..............GNTMKEVKSLLLDLQLLLEKVKNPENLKLSRMHTFNFYMPKvNATELKHLKCLLEELKLLEEVLDLAPSKNLNTREIKDSMDNI......KRIVLELQGSETRFTCEYDDATVKAVEFLNKWITFCQSIYS..............
L9KIU7_TUPCH/7-50                   ..LSCIAFTLVLVTNSAP.T.SSS.T..............VDTKEPLEHLLLDLQKILNGIN-------------------.------------------------------------------......-----------------------------------------a.............
A0A3Q7WXD6_URSAR/7-152              .l-YCIALTLVLVANSAP.T.TSSpT..............KETQQQLEQLLLDLRLLLNGVNNYENPKLSRMLTFKFYMPK.KATELKHLQCLAEELKLLEEVLYLDQSKNLHLTDIKELMSNI......NVTLLKLKGSEASFKCEYDDETVTITEFLNKWITFCQSIFS..............
A0A2K6NXW2_RHIRO/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_RAT/7-151                       ..ASCVALTLVLLVNSAP.T.SSP.A..............KETQQHLEQLLLDLQVLLRGIDNYKNLKLPMMLTFKFYLPK.QATELKHLQCLENELGALQRVLDLTQSKSFHLEDAGNFISNI......RVTVVKLKGSENKFECQFDDEPATVVEFLRRWIAICQSIIS..............
A0A1U7U2W1_TARSY/7-150              ..LSCIALTLALIINSAP.T.SSS.T..............KKTQLQLEHLLLDLQMLLNGVNNDKNTKLPMMLKFKFYVPK.KVTELKHLQCLQGELKPLEEVLNIAESKNFHLKDTRNTISNI......NITVLELKGSETVFMCDYN-ERVTIAEFLNRWITFCQSII-a.............
G5C793_HETGA/7-149                  ..LSCIALTLALITSSAP.T.SSS.T..............RETQEQLEQLLLDLQVILKGVT--RNPKLSKMLKPKLYFPN.KPSELQHLQCLEEELKPLEQVLNLAEHKHFPLINTKDFISNI......NVTVWKLKGSKTTLKCDLNDEEANIVQFLKGWIAFCQKIIS..............
A0A340XUF4_LIPVE/7-151              ..LSCIALTLALVANGAP.T.SSS.T..............ENTKKQVQSLLQDLHLLLKEINNYKNLKLFRMLTFKFYMPK.KATELKHLQCLAEELKPLEDVLNVAQSKTQNSIDIKDLMDNI......NRIVLTLKGSETRFRCEYDDETVTAVEFLNKWITFCQSIYS..............
IL2_PAPAN/7-151                     ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELRPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A384BYP6_URSMA/7-152              .l-YCIALTLVLLANSAP.T.TSSpT..............KETQQQLEQLLLDLRLLLNGVNNYENPKLSRMLTFKFYMPK.KATELKHLQCLAEELKLLEEVLYLDQSKNLHLTDIKELMSNI......NVTLLKLKGSEASFKCEYDDETVTITEFLNKWITFCQSIFS..............
A0A2K6ALW7_MACNE/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2U3W0Y7_ODORO/7-152              ..LSCIALTLVLVANSAP.TtSSS.T..............KETQQQLEQLLLDLRLLLNGVNNYENPKLSRMLTFKFYTPK.KATELTHLQCLAEELKLLEEVLYLAQSKNFHLTDIKELMSNI......NVTLLKLKGSETSFKCEYDDETATITEFLNKWITFCQSIFS..............
A0A2R9ABF1_PANPA/1-131              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_MACFA/7-151                     ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELRHLQCLEEELKPLEEVLNLAQSKSFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
G3S1Y8_GORGO/7-150                  .l-FCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_CANLF/7-152                     ..LSCIALTLVLVANSAPiT.SSS.T..............KETEQQMEQLLLDLQLLLNGVNNYENPQLSRMLTFKFYTPK.KATEFTHLQCLAEELKNLEEVLGLPQSKNVHLTDTKELISNM......NVTLLKLKGSETSYNCEYDDETATITEFLNKWITFCQSIFS..............
A0A1D5RGK2_MACMU/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
B3VBJ5_MESAU/7-151                  ..ASCLALTLALLVSSAP.T.SSS.K..............KETQQHLEQLLLDLQELLKGINNYKNPKLPMMLTFKFYMPK.KATELKHLQCLEEELGALQSVLDLAQSKSFHLEDAENFISNI......RVTVVKLKGSESTFRCEFDDETVTVVEFLNRWITFCQSSI-a.............
A0A2R9ACE1_PANPA/7-150              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
A4GT77_VULVU/7-152                  ..LSCIALMLVLVANSAPiT.SSS.T..............KETEQQMEQLLLDLQLLLNGVNNYENPQLSRMLTFKFYTPK.KATEFTHLQCLAEELKNLEEVLGLPQSKNVHLTDTKELISNM......NVTLLKLKGSETSYNCEYDDETATITEFLNKWITFCQSIFS..............
A0A2Y9KGA6_ENHLU/7-152              ..LSCIVLTLALVANSAP.TtSSS.T..............KEAQQQLEQLLLDLQLLLNGVNNYESLKLPRMLTFKFYMPK.KATELTHLQCLAEELKLLEEVLYLAQSKNFHLTDIKELMSNI......NVTLLKLKGSETSFKCEYDDETVTITEFLNKWITFCQSIFS..............
A0A452SAK8_URSAM/7-152              .l-YCIALTLVLVANSAP.T.TSSpT..............KETQQQLEQLLLDLRLLLNGVNNYENPKLSRMLTFKFYMPK.KATELKHLQCLAEELKLLEEVLYLDQSKNLHLTDIKELMSNI......NVTLLKLKGSEASFKCEYDDETVTITEFLNKWITFCQSIFS..............
A0A2K6GXC5_PROCO/7-149              ..LSCIALTLALVTNSAP.T.SSS.T..............KETRQQLEQLLLDLQMALNRVNNYKNPKLSRMLTFKFYVPK.KATELKHLQCLEDELEALEKVLNLAESKNFHLRDTRELIGNI......NVTVLELKGSET-FTCE-DDETATITEFLNRWITFCQSIIS..............
A0A2K6A5K1_MANLE/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
H2QQ44_PANTR/7-150                  ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2K6NXV7_RHIRO/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2K5J7D7_COLAP/7-151              ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
H0Y254_OTOGA/7-149                  ..LTCIALTFALVTNSAP.I.SSS.T..............KETRQQLEQLLLDLQMVLNGVNNNKNPKLSRMLTLKLYVPK.KATELKHLQCLEEELGPLEKVLDLGQSKNFHLGDTREVIGNI......NVTVLELKGSET-FICE-DNETATIVEFLNRWITFCQSIIS..............
A0A2I3G971_NOMLE/3-129              ri----------------.-.--S.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVQELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
G3VGM5_SARHA/7-137                  ..LSCLALTV-LFASGAP.T.LPP.P..............TT---LLQYLIPDLIEVQKKLND----VSERMKRYELYIPS.NASSIADLQCFTKELNPVAEALKYESR---EAPDIQDHISNI......NLTVNNLMGSEI--QCHYAA-KIKIAGFFQEFITFCQRLI-q.............
A0A2I3MT18_PAPAN/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_HUMAN/7-150                     ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLR-PRDLISNI......NVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIS..............
#=GR IL2_HUMAN/7-150          SS    ..XXXXXXXXXXXXXX--.-.HHH.H..............HHHHHHHHHHHHHHHHHHHHHHTSTHTTHHHHTTSEBEEBS.T-SSGGGGHHHHTTHHHHHHHHHHSCGCSSSSS-HHHHHHHH......HHHHHHHH-SSCCTS--BESSEBEHHHHHHHHHHHHHHHHH..............
IL2_FELCA/7-151                     ..LSCIALTLILVTNSAP.A.SSS.T..............KETQQQLEQLLLDLRLLLNGVNNPENPKLSRMLTFKFYVPK.KATELTHLQCLVEELKPLEEVLYLAQSKNFHLNHIKELMSNI......NVTVLKLKGSETRFTCNYDDETATIVEFLNKWITFCQSIFS..............
W5NPD0_SHEEP/7-158                  ..LSCIALTLALVANGAP.T.SSS.T..............GNTMKEVKSLLLDLQLLLEKVKNPENLKLSRMHTFNFYMPKvNATELKHLKCLLEELKLLEEVLDLAPSKNLNTKNVNVNMFNIlenkghNSIRLELKGSETRFTCEYDDATVKAVEFLNKWITFCQSIYS..............
Q0PIT4_CALJA/7-151                  ..LSCIALSLALITNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMLLNGINNYKNPKLTRMLTFKFYMPK.KAKELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTRDIISNI......NVLVLELKGSETTFTCEYDDDTATIIEFLNGWITFCQSIIS..............
A0A2K5J7H7_COLAP/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
A0A2K5VAX1_MACFA/1-132              .i--------------AP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
I3MQX6_ICTTR/7-151                  ..LSCLALTLALLAHGAP.T.SGS.A..............EETRQQLEHLLLDLQVLSRGVSNQENSTLTRMLKFKFYMPK.KATDLEHLQCLEEELKPLQEVLNVPQSKNFHLKDTRNFISNI......NVTVLKLKGSATTFTCEYAQETANIVEFLNTWITFCQSIIS..............
IL2_VULVU/7-152                     ..LSCIALMLVLVANSAPiT.SSS.T..............KETEQQMEQLLLDLQLLLNGVNNYENPQLSRMLTFKFYTPK.KATEFTHLQCLAEELKNLEEVLGLPQSKNVHLTDTKELISNM......NVTLLKLKGSETSYNCEYDDETATITEFLNKWITFCQSIFS..............
IL2_AILME/7-152                     .l-YCIALTLVLVANSAP.T.PSSpT..............KETQQQLEQLMLDLRLLLNGVNNYENPKLSRMLTFKFYMPK.KATELKHLQCLAEELKLLEEVLYLDQSKNLHLTDIKELMSNI......NVTLLKLKGSEASFKCEYDDETVTITEFLNKWITFCQSIFS..............
A0A2K5MA48_CERAT/7-151              ..LSCIALSLALVANSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
G3VGM6_SARHA/7-137                  ..LSCLALTV-LFASGAP.T.LPP.P..............TT---LLQYLIPDLIEVQKKLND----VSERMKRYELYIPS.NASSIADLQCFTKELNPVAEALKYESR---EAPDIQDHISNI......NLTVNNLMGSEI--QCHYAA-KIKIAGFFQEFITFCQRLI-q.............
IL2_MACNE/7-151                     ..LSCIALSLALVTNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTKDLISNI......NVIVLELKGSETTLMCEYADETATIVEFLNRWITFCQSIIS..............
IL2_AOTNA/7-151                     ..LSCIALSLALITNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMLLNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTRDIISNI......NVLVLELKGSETTFTCEYDDDTATIIEFLNGWITFCQSIIS..............
A0A2K5QJC8_CEBCA/7-151              ..LSCIALSLALISNSAP.T.SSS.T..............KKTQLQLEHLLLDLQMLLNGINNYKNPKLTRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTRDIISNI......NVLVLELKGSETTFTCEYDDDTATIIEFLNGWITFCQSIIS..............
#=GC SS_cons                        ..XXXXXXXXXXXXXX--.-.HHH.H..............HHHHHHHHHHHHHHHHHHHHHHCCTCTTHHHHTCCEEEEBS.T-SSGGGHHHHHHTHHHHHHHHHHCCHCSSCCCCHHHHHHHH......HHHHHHHC-SSSCTS-EBECCEEEHHHHHHHHHHHHHHHHH..............
#=GC seq_cons                       ..LSCIALoLALlsNSAP.T.SSS.T..............KcTQ.QLEpLLLDLQhlLNGlNNY+NPKLoRMLTFKFYMPK.KATELKHLQCLEEELKPLEEVLNLAQSKNFHLcDs+DLISNI......NVhVLcLKGSEToFhCEYsDETATIVEFLN+WITFCQSIIS..............
//
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