GenomeNet

Database: Pfam
Entry: IL22
LinkDB: IL22
Original site: IL22 
#=GF ID   IL22
#=GF AC   PF14565.7
#=GF DE   Interleukin 22 IL-10-related T-cell-derived-inducible factor
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9GZX6
#=GF GA   30.00 30.00;
#=GF TC   30.20 30.00;
#=GF NC   29.90 29.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Interleukin
#=GF RN   [1]
#=GF RM   10875937
#=GF RT   Interleukin (IL)-22, a novel human cytokine that signals through
#=GF RT   the interferon receptor-related proteins CRF2-4 and IL-22R.
#=GF RA   Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood
#=GF RA   WI, Goddard AD, Gurney AL;
#=GF RL   J Biol Chem. 2000;275:31335-31339.
#=GF RN   [2]
#=GF RM   12176383
#=GF RT   Crystal structure of recombinant human interleukin-22.
#=GF RA   Nagem RA, Colau D, Dumoutier L, Renauld JC, Ogata C, Polikarpov
#=GF RA   I;
#=GF RL   Structure. 2002;10:1051-1062.
#=GF DR   INTERPRO; IPR020453;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Interleukin-22 is distantly related to interleukin (IL)-10, and
#=GF CC   is produced by activated T cells. IL-22 is a ligand for CRF2-4,
#=GF CC   a member of the class II cytokine receptor family.
#=GF SQ   148
#=GS A0A384BIR1_URSMA/40-178   AC A0A384BIR1.1
#=GS A0A2Y9IQV7_ENHLU/39-177   AC A0A2Y9IQV7.1
#=GS A0A452HGC2_9SAUR/45-143   AC A0A452HGC2.1
#=GS A0A3B4UQN4_SERDU/42-178   AC A0A3B4UQN4.1
#=GS A0A3P8UTJ8_CYNSE/56-190   AC A0A3P8UTJ8.1
#=GS G3VJZ8_SARHA/37-175       AC G3VJZ8.1
#=GS A0A3Q3A7H2_KRYMA/39-176   AC A0A3Q3A7H2.1
#=GS A0A3B3VUH8_9TELE/50-177   AC A0A3B3VUH8.1
#=GS H2AKX1_SHEEP/40-179       AC H2AKX1.1
#=GS G1LQ37_AILME/40-178       AC G1LQ37.1
#=GS I3KNL8_ORENI/49-179       AC I3KNL8.1
#=GS B6RD04_XENTR/46-182       AC B6RD04.1
#=GS A0A093GYJ0_DRYPU/46-182   AC A0A093GYJ0.1
#=GS A0A3B3XUE0_9TELE/55-177   AC A0A3B3XUE0.1
#=GS F1SH68_PIG/40-179         AC F1SH68.1
#=GS A0A3B3R0V9_9TELE/33-166   AC A0A3B3R0V9.1
#=GS A0A384B651_BALAS/40-179   AC A0A384B651.1
#=GS A0A087QQC2_APTFO/46-184   AC A0A087QQC2.1
#=GS A0A151PFM0_ALLMI/42-179   AC A0A151PFM0.1
#=GS A0A3P8Y9D6_ESOLU/36-167   AC A0A3P8Y9D6.1
#=GS G1SFV3_RABIT/40-177       AC G1SFV3.2
#=GS A0A093HD10_STRCA/46-184   AC A0A093HD10.1
#=GS E1A9L4_CAPHI/40-179       AC E1A9L4.1
#=GS G7PHZ7_MACFA/40-178       AC G7PHZ7.1
#=GS A0A2U3Y8X9_LEPWE/40-178   AC A0A2U3Y8X9.1
#=GS I3MJR9_ICTTR/40-178       AC I3MJR9.1
#=GS A0A3B4AUA0_9GOBI/79-179   AC A0A3B4AUA0.1
#=GS A0A2D0T5Y2_ICTPU/25-171   AC A0A2D0T5Y2.1
#=GS A0A091JM42_EGRGA/46-184   AC A0A091JM42.1
#=GS G3TZD5_LOXAF/40-181       AC G3TZD5.1
#=GS F6PQU1_ORNAN/41-179       AC F6PQU1.1
#=GS E1C1U2_CHICK/46-184       AC E1C1U2.1
#=GS A0A1S3A2V2_ERIEU/40-178   AC A0A1S3A2V2.1
#=GS A0A2I4CSW2_9TELE/44-176   AC A0A2I4CSW2.1
#=GS A0A3Q3MU76_9TELE/39-174   AC A0A3Q3MU76.1
#=GS G3TV87_LOXAF/40-178       AC G3TV87.1
#=GS A0A3P9NDZ4_POERE/47-177   AC A0A3P9NDZ4.1
#=GS A0A2Y9N1X5_DELLE/40-178   AC A0A2Y9N1X5.1
#=GS IL22_HUMAN/40-178         AC Q9GZX6.1
#=GS IL22_HUMAN/40-178         DR PDB; 1M4R A; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1YKB F; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1YKB A; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1YKB D; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 3G9V D; 41-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1YKB C; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 3DGC M; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1YKB E; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 3Q1S I; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 3DGC L; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1YKB B; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 1M4R B; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 3G9V B; 40-178;
#=GS IL22_HUMAN/40-178         DR PDB; 3DLQ I; 40-178;
#=GS A0A452HGC1_9SAUR/45-183   AC A0A452HGC1.1
#=GS A0A096NE66_PAPAN/40-178   AC A0A096NE66.1
#=GS A0A3Q7T9C9_VULVU/40-178   AC A0A3Q7T9C9.1
#=GS M3ZWG2_XIPMA/47-177       AC M3ZWG2.2
#=GS A0A2J8K4Y0_PANTR/40-178   AC A0A2J8K4Y0.1
#=GS F6XDH7_MONDO/38-181       AC F6XDH7.1
#=GS A0A2K5REN2_CEBCA/40-178   AC A0A2K5REN2.1
#=GS A0A401PAR6_SCYTO/40-172   AC A0A401PAR6.1
#=GS A0A287D857_ICTTR/74-217   AC A0A287D857.1
#=GS H0WPM1_OTOGA/40-178       AC H0WPM1.1
#=GS G3WHH1_SARHA/37-175       AC G3WHH1.1
#=GS A0A1L8GYL0_XENLA/47-182   AC A0A1L8GYL0.1
#=GS A0A401SN32_CHIPU/36-172   AC A0A401SN32.1
#=GS A0A2U3WC28_ODORO/40-178   AC A0A2U3WC28.1
#=GS A0A3Q0S6J3_AMPCI/44-174   AC A0A3Q0S6J3.1
#=GS A0A3B4BXF0_PYGNA/21-155   AC A0A3B4BXF0.1
#=GS G3TXH8_LOXAF/40-178       AC G3TXH8.1
#=GS A0A2K6BGF3_MACNE/40-178   AC A0A2K6BGF3.1
#=GS A0A498M1M7_LABRO/28-166   AC A0A498M1M7.1
#=GS L9L0Z1_TUPCH/39-177       AC L9L0Z1.1
#=GS A0A3P8U4A6_AMPPE/68-184   AC A0A3P8U4A6.1
#=GS A0A2K5JUR6_COLAP/40-178   AC A0A2K5JUR6.1
#=GS A0A2K5ZZP7_MANLE/40-178   AC A0A2K5ZZP7.1
#=GS F6ZMP3_MONDO/36-155       AC F6ZMP3.2
#=GS M3Z1D7_MUSPF/39-177       AC M3Z1D7.1
#=GS IL22B_MOUSE/40-178        AC Q9JJY8.2
#=GS A0A087X710_POEFO/55-177   AC A0A087X710.1
#=GS R0KSK0_ANAPL/46-184       AC R0KSK0.1
#=GS A0A2K5DDQ0_AOTNA/40-178   AC A0A2K5DDQ0.1
#=GS A0A3B5B6F7_9TELE/80-177   AC A0A3B5B6F7.1
#=GS A0A2Y9G2H0_TRIMA/40-178   AC A0A2Y9G2H0.1
#=GS A0A3B4Y1R6_SERLL/42-178   AC A0A3B4Y1R6.1
#=GS A0A3Q1C1K4_AMPOC/80-184   AC A0A3Q1C1K4.1
#=GS A0A226MP71_CALSU/46-184   AC A0A226MP71.1
#=GS A0A402EN16_9SAUR/48-147   AC A0A402EN16.1
#=GS A0A2K6UL79_SAIBB/40-178   AC A0A2K6UL79.1
#=GS A0A340XU04_LIPVE/40-178   AC A0A340XU04.1
#=GS A0A0D9QWD6_CHLSB/40-178   AC A0A0D9QWD6.1
#=GS A0A2J8W0T4_PONAB/40-178   AC A0A2J8W0T4.1
#=GS L5JVH5_PTEAL/40-178       AC L5JVH5.1
#=GS H0Z8L5_TAEGU/43-181       AC H0Z8L5.1
#=GS A0A3B3CRV8_ORYME/36-167   AC A0A3B3CRV8.1
#=GS G3TAL5_LOXAF/36-180       AC G3TAL5.1
#=GS M7BDI3_CHEMY/362-489      AC M7BDI3.1
#=GS A0A2K6PCP6_RHIRO/40-178   AC A0A2K6PCP6.1
#=GS A0A2Y9E3G0_TRIMA/40-178   AC A0A2Y9E3G0.1
#=GS A0A2I0MJX1_COLLI/45-183   AC A0A2I0MJX1.1
#=GS L5JVE0_PTEAL/32-181       AC L5JVE0.1
#=GS A0A091IK75_CALAN/46-184   AC A0A091IK75.1
#=GS A0A3Q2DF17_CYPVA/47-174   AC A0A3Q2DF17.1
#=GS A0A2Y9E4Y0_TRIMA/40-178   AC A0A2Y9E4Y0.1
#=GS A0A2Y9EQJ2_PHYMC/40-178   AC A0A2Y9EQJ2.1
#=GS A0A3L8SQ08_CHLGU/43-181   AC A0A3L8SQ08.1
#=GS A0A093QGF7_9PASS/41-179   AC A0A093QGF7.1
#=GS M3WMS8_FELCA/40-178       AC M3WMS8.1
#=GS A0A3Q3LW29_9LABR/47-179   AC A0A3Q3LW29.1
#=GS G1NYG9_MYOLU/40-178       AC G1NYG9.1
#=GS A0A3B3QJT2_9TELE/27-167   AC A0A3B3QJT2.1
#=GS A0A091WZ26_OPIHO/46-184   AC A0A091WZ26.1
#=GS H3A664_LATCH/45-187       AC H3A664.1
#=GS A0A2K6GJ76_PROCO/40-178   AC A0A2K6GJ76.1
#=GS A0A2U3ZLF9_ODORO/40-178   AC A0A2U3ZLF9.1
#=GS A0A060XIV4_ONCMY/36-170   AC A0A060XIV4.1
#=GS A0A3Q1JG59_ANATE/35-170   AC A0A3Q1JG59.1
#=GS H9G878_ANOCA/43-181       AC H9G878.1
#=GS H0VFP5_CAVPO/39-176       AC H0VFP5.2
#=GS A0A1V4J9R3_PATFA/45-183   AC A0A1V4J9R3.1
#=GS A0A1U7RPJ3_ALLSI/42-179   AC A0A1U7RPJ3.1
#=GS IL22_MOUSE/40-178         AC Q9JJY9.1
#=GS A0A1U7UHM1_TARSY/41-179   AC A0A1U7UHM1.1
#=GS U3IZB0_ANAPP/46-184       AC U3IZB0.1
#=GS A0A1S3FC05_DIPOR/40-178   AC A0A1S3FC05.1
#=GS G3R0Q5_GORGO/40-178       AC G3R0Q5.1
#=GS A0A3B3HWH6_ORYLA/52-179   AC A0A3B3HWH6.1
#=GS A0A3Q7WYF1_URSAR/40-178   AC A0A3Q7WYF1.1
#=GS A0A091CY89_FUKDA/735-872  AC A0A091CY89.1
#=GS A0A1U7R863_MESAU/41-179   AC A0A1U7R863.1
#=GS F7DY14_HORSE/40-178       AC F7DY14.1
#=GS F6PQU9_ORNAN/41-184       AC F6PQU9.1
#=GS A0A2K6MV29_RHIBE/40-178   AC A0A2K6MV29.1
#=GS E2R2K7_CANLF/40-178       AC E2R2K7.1
#=GS A0A2R8ZS67_PANPA/40-178   AC A0A2R8ZS67.1
#=GS F6WL87_CALJA/40-178       AC F6WL87.1
#=GS A0A3Q1G8C2_9TELE/67-184   AC A0A3Q1G8C2.1
#=GS A0A3B4AVD4_9GOBI/37-175   AC A0A3B4AVD4.1
#=GS A0A3B3RN56_9TELE/38-177   AC A0A3B3RN56.1
#=GS A0A226P0Q4_COLVI/46-184   AC A0A226P0Q4.1
#=GS A0A091G7B7_9AVES/46-184   AC A0A091G7B7.1
#=GS A0A218V425_9PASE/1-88     AC A0A218V425.1
#=GS A0A2K5NDW2_CERAT/40-176   AC A0A2K5NDW2.1
#=GS A0A452RY20_URSAM/40-178   AC A0A452RY20.1
#=GS A0A2U3V8J7_TURTR/40-178   AC A0A2U3V8J7.1
#=GS U3K667_FICAL/43-183       AC U3K667.1
#=GS F6YBU5_MACMU/40-178       AC F6YBU5.1
#=GS A0A091EPC6_CORBR/43-181   AC A0A091EPC6.1
#=GS A0A1S3P5V7_SALSA/34-170   AC A0A1S3P5V7.1
#=GS G1NDB2_MELGA/46-184       AC G1NDB2.2
#=GS I3M7Y2_ICTTR/36-179       AC I3M7Y2.2
#=GS A0A3M0KBX0_HIRRU/488-626  AC A0A3M0KBX0.1
#=GS G3V6X6_RAT/40-178         AC G3V6X6.1
#=GS A5JS75_BOVIN/40-179       AC A5JS75.1
#=GS A0A3Q4HMR6_NEOBR/52-176   AC A0A3Q4HMR6.1
#=GS G1QTK0_NOMLE/40-178       AC G1QTK0.1
#=GS A0A2U3Y8K1_LEPWE/40-178   AC A0A2U3Y8K1.1
#=GS A0A4D9ED44_9SAUR/15-153   AC A0A4D9ED44.1
#=GS G5BGB6_HETGA/40-177       AC G5BGB6.1
#=GS K7GEW3_PELSI/42-180       AC K7GEW3.1
#=GS A0A0A0APS8_CHAVO/46-184   AC A0A0A0APS8.1
#=GS A0A091UXW4_NIPNI/46-184   AC A0A091UXW4.1
A0A384BIR1_URSMA/40-178              ..........................................CRLNSSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DQLFHGV...N..M.GD....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.H.I....E.R...D...D...Q...H..I...Q....R.N...VQN...LKD..T.V..TKL.G.E.N.GEIKAIGE.LNLLFIALKNAC.....
A0A2Y9IQV7_ENHLU/39-177              ..........................................CRLANSDFEQPYITNRTFMLAGEAS.L.ADNN..TDVRLI.G.DTLFHGV...N..R.GD....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LT....KLSN.R.LS.Q..C.H.I....D.S...D...D...Q...H..I...Q....R.N...VEN...LKD..T.V..KKL.G.E.D.GEIKAIGE.LNLLFIALRDAC.....
A0A452HGC2_9SAUR/45-143              ..........................................CRLRKISFQQSYIRNRTYTLAKLAR.L.SDQD..TDNRLI.G.QQLYINV...Q..E.TN....RCYVMKRVIEIIVDEVL.......L...S.......A........P.......K...N....R......Y........PH......IH....E....V...A....QF....LA....ALRT.E.LS.G..C.V.-....-.-...-...-...-...-..-...-....-.-...---...---..-.-..---.-.-.-.--------.------------smahf
A0A3B4UQN4_SERDU/42-178              ..................................sqplrnpq----------TYQAVRDVSQHAQSQ.Q.TDDD..SSSRLM.P.RVTNTNQ...D..H.LK....ICCLHANILDFYLNNIL.......-...R.......H........R.......D...N....Q......H........PS......MH....R....L...K....TD....LS....RVSE.D.LK.T..Q.G.C....N.V...T...H...Y...H..D...H....H.H...AVE...FRR..K.L..AMMgG.E.Q.GMNKAVGE.IDILFTYLQDFC.....
A0A3P8UTJ8_CYNSE/56-190              pvlrnkdtyqavhevskhfqgletadesstkllpnvdrnkdh-------------------------.-.----..------.-.-------...-..-.MS....ICCLHANILDFYMNNIL.......T...H.......H........C.......K...R....H......D........KI......LR....L....K...V....-D....LA....RVSE.D.LQ.T..H.G.C....N.V...T...H...Y...H..D...D....H.H...AVE...FRK..K.L..AKMdG.E.R.GIIKAVGE.IDILFSFLTDYC.....
G3VJZ8_SARHA/37-175                  ..........................................CKIARSIFQARHINNQIHDLSKMAS.D.ADDD..TTTRFI.G.HLIVKDV...Q..E.TN....RCYVMKEVLNFQLREVL.......L...S.......Y........E.......Q...K....Y......E........KY......MR....D....V...L....PF....LN....NVKS.K.LS.S..C.T.M....N.G...D...T...S...K..V...R....R.T...IDD...MRS..K.V..KKL.G.K.H.AVVKAMSE.MDMMLLYLRGYC.....
A0A3Q3A7H2_KRYMA/39-176              .................sfsrplqdpkthsavrevsqhaqrq-------------------------.Q.QEED..TSSRLM.P.-RVKTNQ...S..N.VE....ICCLHANILDFYLNNIL.......H...-.......H........Y.......D...N....Q......H........PR......MH....R....L...K....TD....LH....RVSE.D.LQ.A..Q.G.C....N.V...T...H...Y...H..D...H....H.H...VVE...FRQ..K.L..EKIeG.E.R.GITKAVGE.IDILFTYLHDYC.....
A0A3B3VUH8_9TELE/50-177              .........................thediqklsvhaqrkel-------------------------.-.-EED..TSIRLM.P.-RVDTNQ...N..H.ME....ICCLHANILNFYLNNIL.......H...K.......Y........S.......E...E....-......H........PS......MH....K....L...Q....TD....LH....RVSS.D.LQ.T..Q.G.C....N.V...T...H...Y...H..N...H....R.H...AVE...FRR..K.L..ERMeG.E.R.GINKAIGE.IDILFTYLHDFC.....
H2AKX1_SHEEP/40-179                  ..........................................CRLNKSDFQEPYIFNHTFTLAQEAS.L.ADNI..TDVRLI.G.NKLFQGI...N..QvTK....RCYVLKQVLNFILEEVL.......F...P.......R........S.......D...E....F......H........PH......MK....K....V...V....PF....FS....KLSK.K.LS.Q..C.H.I....E.N...D...N...Q...H..I...Q....R.N...VQN...LKN..T.V..KKL.G.E.S.GEIKVIGE.LNLLFITLKREC.....
G1LQ37_AILME/40-178                  ..........................................CRLNSSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DQLFHGV...N..M.GD....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.H.I....E.S...D...D...Q...H..I...H....R.N...VQN...LKD..T.V..TKL.G.E.N.GEIKAIGE.LNLLFIALKNAC.....
I3KNL8_ORENI/49-179                  ........................tyqdvrqvsehyqriqak-------------------------.D.DEDD..TSMRTI.P.-KVDTND...H..H.LE....ICCLHANILDYYLTNIL.......H...H.......-........T.......N...N....D......H........AH......VH....R....L...K....TN....LH....RIST.D.LQ.A..H.G.C....N.V...T...Q...Y...H..D...H....K.N...AVD...FRT..K.L..EKM.E.KkK.GITKAIGE.LDILFSYLQDYC.....
B6RD04_XENTR/46-182                  ..........................................CTIRKTFFLQTFMKKNIFALAEQAR.I.MDKD..TANKIF.G.SYLFFGV...K..E.KD....HCYLMKNVVNSFVENVL.......H...-.......E........S.......S...K....K......Y........PH......ID....N....A...I....AF....FV....NIEK.D.LA.G..C.K.S....E.E...G...-...D...Q..I...Q....R.N...VEQ...MIN..K.I..KMM.G.P.D.GKNKAIGE.LDLLFAHLRK--ct...
A0A093GYJ0_DRYPU/46-182              ..........................................CRLRRINF-QPYIRNHTYTLAKMVQ.V.SDHD..TDNRLI.G.QQLYANI...K..E.NN....HCYMMKRTVEMVVKDVL.......L...T.......E........A.......K...N....Q......Y........LY......AK....E....V...A....EF....LA....SLTQ.Q.LR.H..C.-.V....S.R...Q...R...E...H..I...E....K.N...LEE...MKR..K.M..EEL.G.E.N.GKTKAIGE.LDLLFDYIENAC.....
A0A3B3XUE0_9TELE/55-177              ..............................gklsahaqrkel-------------------------.-.-EED..TSIRLM.P.-RVNTDQ...N..H.ME....ICCLHANILNFYLNNIL.......H...K.......Y........S.......E...E....-......H........PS......MH....K....L...Q....TD....LH....RVSS.D.LQ.T..Q.G.C....N.V...T...H...Y...H..N...H....R.H...AVE...FRR..K.L..ERMeG.E.R.GINKAVGE.IDILFTYLHDFC.....
F1SH68_PIG/40-179                    ..........................................CKLDQSNFQQPYITNRTFTLAQEAS.L.ADNN..TDVRLI.G.NNLFQGV...N.qM.RE....RCYLVKQVLNFTLEEVL.......F...P.......N........S.......D...R....F......H........PY......MQ....E....V...A....SF....LD....SLSK.K.LS.Q..C.R.I....K.G...D...D...Q...H..I...Q....R.N...VNN...FKD..T.V..KKL.G.E.S.GEIKVIGE.LYLLFMALKNEC.....
A0A3B3R0V9_9TELE/33-166              ............................rspplgnqhtmqhv-----------------QKLAQAAQ.E.FDEE..ANIRLI.P.KFQHTKN...M..N.LY....VCCLHANILDFYLWNIL.......T...T.......E........-.......-...N....N......Y........PS......LE....K....V...R....TD....LG....RVSR.D.LS.EqgC.S.I....M.H...V...D...N...H..-...-....E.Y...SRK...FKE..G.F..HKL.G.K.T.AVNKAIGE.IDILFDSLNIFC.....
A0A384B651_BALAS/40-179              ..........................................CSLDRANFQQPYITNRTFALAQEAS.L.ADNN..TDVRLI.G.TKLFQGV...N.qM.TE....RCYMLKQVLNFILEEML.......L...P.......Q........S.......N...R....F......K........PY......MQ....E....V...V....PF....LA....RLNK.K.LG.Q..C.H.I....E.C...D...N...Q...N..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKVIGE.LNLLFMALKNEC.....
A0A087QQC2_APTFO/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAKMVQ.V.SDQD..TDNRLI.G.QQLYVNV...K..E.NN....HCYMMKRIVEIVVKDVL.......L...T.......K........A.......K...D....Q......Y........PY......VE....E....V...A....QF....LA....SLNS.E.LS.R..C.K.S....S.G...L...R...D...H..I...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYIENAC.....
A0A151PFM0_ALLMI/42-179              ..........................................CKLEKIYFQQPYIRNCTYTLAKEAR.L.LDQD..TENRFI.G.QQLYVNV...K..E.SN....RCYVMKSVLEIITKEVL.......S...-.......N........L.......K...N....K......N........QH......IH....E....V...I....HF....LE....VLRL.K.LH.G..C.K.F....S.G...H...R...E...H..V...E....R.N...LAE...MKN..R.M..KQL.G.D.N.GKNKAIGE.LDLLFDYMEDAC.....
A0A3P8Y9D6_ESOLU/36-167              ..............................plqnadtdalvq------------------QVARHAQ.S.SDTD..TNVKLM.P.D-VDTKK...N..H.RD....ICCLHANILDFYLSNIL.......I...S.......D........N.......H...-....K......H........PK......LP....E....L...K....EH....LA....RVSK.D.LK.D..H.G.C....A.V...K...H...Y...S..N...D....R.H...NIA...FRK..K.L..SEM.GgG.K.GIRKAIGE.IDILFTYLKDFC.....
G1SFV3_RABIT/40-177                  ..........................................CRLDESNFT-SYITNLTFMLAKEAN.S.ADNN..TDVRLI.G.NELFHGV...N..E.KD....HCYLLKHVLNFTLEEVL.......F...P.......E........S.......D...R....F......Q........PY......MQ....Q....V...L....SF....LA....KLSN.N.LS.Q..C.H.I....E.G...D...D...Q...H..I...Q....R.N...VQQ...LKD..T.V..KQL.G.E.S.GEIKAIGE.LDLLFMALRTAC.....
A0A093HD10_STRCA/46-184              ..........................................CRLRKINFLQPYIRNRTYTLAKMVQ.V.SDED..TDNRLI.G.QQLYVNI...K..E.NN....RCYMMKRVAEIIVKDVL.......L...S.......E........A.......K...D....Q......Y........PY......TE....E....V...A....QF....LA....SMTS.E.LS.R..C.K.F....S.G...S...R...E...H..I...E....K.N...LEE...MKS..K.M..KQL.G.A.N.GKNKAIGE.LDLLFDYIENAC.....
E1A9L4_CAPHI/40-179                  ..........................................CRLNKSDFQEPYIFNHTFTLAQEAS.L.ADNI..TDVRLI.G.NKLFQGI...N..QvTK....RCYVLKQVLNFILEEVL.......F...P.......R........S.......D...E....F......H........PH......MK....K....V...V....PF....FS....KLSK.K.LS.Q..C.H.I....E.N...D...N...E...H..I...Q....R.N...VQN...LKN..T.V..KKL.G.E.S.GEIKVIGE.LNLLFITLKREC.....
G7PHZ7_MACFA/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.S.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A2U3Y8X9_LEPWE/40-178              ..........................................CRLNHSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DKLFHGV...N..A.GE....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.R.I....E.S...D...E...Q...H..I...Q....R.N...VQM...LKD..T.V..KKL.G.E.N.GEIKAIGE.LSLLFIALRNAC.....
I3MJR9_ICTTR/40-178                  ..........................................CGLHKASFEGPFIINRTFLLAEEAS.F.ADNN..TDVRLI.D.DRLYQGV...S..M.KD....RCYVMKQVLNFTLEEVL.......L...P.......N........S.......D...R....P......L........PY......LQ....D....V...V....SF....LE....GLNN.D.LR.L..C.H.I....K.G...D...N...R...H..I...Q....K.N...VQN...LKD..T.V..EKL.G.E.S.GVIKVIGE.LNLLFFYLKNAC.....
A0A3B4AUA0_9GOBI/79-179              .............................alylrtshyfdhl-------------------------.-.----..------.-.-------...-..-.-K....ICCLHANILDFYLRNI-.......L...P.......R........H.......D...N....K......H........PH......MH....R....V...R....TD....LQ....RVSE.D.LK.T..Q.G.C....N.V...T...H...Y...H..D...H....R.H...AVQ...FR-..-.-..KKL.A.E.Q.GINKAVGE.INILFSYLQDFC.....
A0A2D0T5Y2_ICTPU/25-171              .........................................a-RLRSRPLDNPDTWNNVMVMAKHAQ.A.QDRD..HETRLI.P.VISSDKL...K..D.GD....VCCANVKILDYYLRHIL.......D...G.......K........A.......H...EgredN......Y........PR......IH....L....V...K....PD....LN....RVAR.D.LEpH..C.N.A....K.Q..iD...L...E...H..L...Q....T.F...KQN...LNRagE.M..YKN.N.T.K.AQNKAIGE.TDILFHYLYESC.....
A0A091JM42_EGRGA/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAKMVQ.V.SDQD..TDNRFI.G.QQLYINI...K..E.NN....RCYMMKKIVEIVVKDVL.......L...T.......E........A.......K...D....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LS.R..C.K.L....S.G...H...R...E...H..I...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYIENAC.....
G3TZD5_LOXAF/40-181                  ..........................................CRLDKANFQQSYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGIhalQ..M.SE....RCYLMKQVLNFTLVEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LD....RLSN.K.LS.Q..C.H.I....Q.G...N...D...Q...H..I...Q....R.N...VQK...LKG..T.V..KKL.G.E.S.GEIKAIGE.LGLLFLALRNAC.....
F6PQU1_ORNAN/41-179                  ..........................................CRLKNSDFEVSFINQRILNLSKKAS.D.QDTI..TDIRLI.N.STFPQDV...Q..V.GD....RCYLMKQILNFTLEVVI.......P...P.......Q........Y.......T...Q....L......M........PF......IQ....D....V...E....SF....FS....DLHR.K.LR.Y..C.N.T....V.S...G...G...Q...H..V...E....S.H...VET...LKK..T.V..TKL.G.K.K.GMNKVIGE.LNLLFMALKHAC.....
E1C1U2_CHICK/46-184                  ..........................................CRLRKINFQQPYIRNRTYTLAEMAR.L.SDQD..TDNRLI.G.QQIYVNI...R..E.NN....RCYMMKRITEIIVKDVL.......L...T.......E........A.......K...E....R......Y........PY......AE....D....V...A....QF....LA....SLTS.E.LS.R..C.K.Y....S.G...N...R...E...H..I...E....K.N...LEE...MKS..K.M..KEL.G.E.N.GKNKAIGE.LDLLFDYIENAC.....
A0A1S3A2V2_ERIEU/40-178              ..........................................CRLDKSNFQQPYINNRTFMLANEAS.M.ADNN..TDVRLI.G.ENLYHGV...N..I.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........Q.......D...K....F......Q........PY......MQ....E....V...V....PF....FA....RLNN.M.LR.Q..C.H.S....K.S...D...A...Q...Q..I...Q....R.N...VQE...LQD..T.V..RKL.G.E.S.GEIKVIGE.LNLLFIYLKDAC.....
A0A2I4CSW2_9TELE/44-176              .....................lqdpkthgairevsqhaqrkq-------------------------.-.PEED..TSSRLM.P.-RVNTNQ...N..N.VE....ICCLHANILDFYLHNIL.......H...-.......H........Y.......D...S....E......H........PS......MH....Q....L...K....TD....LH....RVSQ.D.LQ.A..Q.G.C....N.V...T...H...Y...H..D...H....Q.H...AVE...FRK..K.L..EKMeG.E.R.GINKAVGE.IDILFTYLHDYC.....
A0A3Q3MU76_9TELE/39-174              ......sqplrsldtyqavrevsqhaqtmeteadsssrlmpr-------------------------.-.----..------.-.--VNTDQ...D..H.LK....ICCLHANILDFYLHNIL.......-...R.......Q........G.......D...N....Q......H........PK......MH....R....L...Q....TD....LT....RVSE.D.LQ.T..H.G.C....N.V...T...H...Y...H..D...H....H.H...AVE...FRR..K.L..AKMgG.E.R.GINKAVGE.IDILFTYLQDFC.....
G3TV87_LOXAF/40-178                  ..........................................CRLDKANFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...H..M.SE....RCYLMKQVLNFTLVEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....SF....LD....RLSN.K.LS.Q..C.H.I....Q.G...N...D...Q...H..I...Q....T.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LGLLFMALRNAC.....
A0A3P9NDZ4_POERE/47-177              ......................dpkthedirelsqhaqrkel-------------------------.-.-EED..TSIRLM.P.-RVNTDQ...K..H.ME....ICCLHANILNFYLNNIL.......H...K.......Y........S.......E...E....-......H........PS......MH....K....L...Q....TD....LH....RVSS.D.LQ.T..Q.G.C....N.V...T...H...Y...H..D...H....R.N...AVE...FRR..K.L..ERMeG.E.R.GINKAVGE.IDILFTYLHDFC.....
A0A2Y9N1X5_DELLE/40-178              ..........................................CRLDRANFQQPYITNRTFALAHEAS.L.ADNN..TDVRLI.G.TKLFQGV...K..M.ME....RCCMLKQVLNFTLEEVL.......L...P.......Q........S.......N...R....F......K........PY......MQ....E....V...V....PF....LA....RLNK.K.LG.Q..C.H.M....E.C...D...N...Q...N..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKVIGE.LNLLFMALKNEC.....
IL22_HUMAN/40-178                    ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...S..M.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
#=GR IL22_HUMAN/40-178         SS    ..........................................S---GGGG-SHHHHHHHHHHHHHHH.H.TSTT..TSS-SS.S.GGGGTT-...-..G.GG....HHHHHHHHHHHHHHHTT.......T...T.......T........T.......T...S....S......T........TH......HH....H....H...H....HH....HH....HHHH.H.HT.T..-.-.-....S.S...-...S...H...H..H...H....H.H...HHH...HHH..H.H..HHT.H.H.H.HHHHHHHT.HHHHHHHHHHHH.....
A0A452HGC1_9SAUR/45-183              ..........................................CRLRKISFQQSYIRNRTYTLAKLAR.L.SDQD..TDNRLI.G.QQLYINV...Q..E.TN....RCYVMKRVIEIIVDEVL.......L...S.......A........P.......K...N....R......Y........PH......IH....E....V...A....QF....LA....ALRT.E.LS.G..C.K.F....S.G...H...R...E...H..I...E....K.N...LAE...MKD..K.M..KQL.G.V.S.GKNKAIGE.LDLLFDYMENAC.....
A0A096NE66_PAPAN/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A3Q7T9C9_VULVU/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...N..M.GE....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.K.LS.Q..C.H.I....E.N...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..QKL.G.E.N.GEIKAIGE.LDLLFMALRNAC.....
M3ZWG2_XIPMA/47-177                  ......................dpkthedirelsqhaqrkel-------------------------.-.-EED..TSIRLM.P.-RVNTDQ...N..H.ME....ICCLHANILNFYLNNIL.......H...K.......Y........S.......E...E....-......H........PS......MH....R....L...Q....TD....LH....RVSS.D.LQ.T..Q.G.C....N.V...T...H...Y...H..D...H....R.H...AVE...FRR..K.L..ERMeG.E.R.GINKAVGE.IDILFTYLHDFC.....
A0A2J8K4Y0_PANTR/40-178              ..........................................CRLDKSSFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...S..M.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.N.GEIKAIGE.LDLLFMSLRNAC.....
F6XDH7_MONDO/38-181                  ........................vqrailrdlwrafqamkn----------------------TVQ.A.LDCD..TDTRLL.R.QEFLRNA...S..W.AE....ICHLTNSLLDFYLKNIF.......KnykT.......K........A.......A...Kl.giL......P........PF......MS....L....A...N....NF....FA....IL-Q.K.FK.R..C.K.E....R.GllpS...N...E...S..A...Q....R.K...FEL...FQQ..E.F..TQL.NpE.V.RLTKALGE.VDILLTWMEKA-f....
A0A2K5REN2_CEBCA/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....SF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A401PAR6_SCYTO/40-172              ....................................qllrgm-------------RHKVHALSKEAQ.E.IDED..TDTRLI.G.KDLFQGL...E..G.HD....GCYVLKEVIDFYLGNVL.......A...S......dE........L.......H...H....R......Y........SR......LQ....E....V...K....EF....LA....ILTR.RhMS.D..C.G.V....A.Q...K...R...-...Q..A...N....D.N...IDG...LKQ..K.L..NQL.R.E.T.REAKVIGE.LFMLLQELGKHC.....
A0A287D857_ICTTR/74-217              ..........................................CRAEGVNLQQ--LREAFWTIQETVQ.A.QDNT..TSVRLL.R.QEVLQNV...S..D.AE....SCYLIHALLKFYLNTVF.......K...N.......Y........H.......K...R....A......EfktlksfsTL......AN....N....F...I....VI....MS....KLQP.S.QE.N..E.M.F....-.S...V...S...E...S..A...H....K.R...FLL...FHR..A.F..KRL.DiE.A.ALTKALGE.VDILLTWME---kf...
H0WPM1_OTOGA/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...N..M.GE....RCYLLKQVLNFTVDEVL.......L...P.......Q........P.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....RLST.R.LS.S..C.H.I....E.G...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..RKL.G.E.S.GEIKAIGE.LDLLFMALRNAC.....
G3WHH1_SARHA/37-175                  ..........................................CKIARSIFQARHINNQIYYLSKMAS.D.ADDD..TTTRFI.S.RLIVKDV...E..E.TN....RCYVMKEVLNFQLREVL.......L...S.......Y........E.......Q...K....Y......E........KY......MR....D....V...L....PF....LN....NVKS.M.LS.S..C.T.M....N.G...D...T...R...K..V...Q....R.T...IND...MRS..K.V..QKL.G.K.H.AVVKAMSE.MDMMLLYLRGYC.....
A0A1L8GYL0_XENLA/47-182              ..........................................CTIRKTYFLQTFMKKNIFTLAEQAR.I.MDKD..TDNKLF.G.SYLFFGI...K..E.KD....HCYLMKNVVSSIVENVL.......H...D.......N........S.......K...-....K......Y........PH......ID....N....A...I....VF....LL....NIQK.D.LA.G..C.K.S....E.-...E...E...D...H..I...R....K.N...VEQ...MIN..K.M..KMK.D.N.I.TGIKFLTEnLKVDFM------aqkn.
A0A401SN32_CHIPU/36-172              ..................................hveeqllr-----------YMRHKFHALSNEAQ.K.IDTD..TDTRLI.G.KDLFQGL...Q..G.HG....RCYVLKEVIDFYLGNVL.......S...S.......E........D......lH...A....K......Y........SH......LK....E....I...K....EF....LA....LLTK.QhMS.D..C.N.T....K.-...N...R...T...Q..A...K....H.N...IDL...LKQ..K.L..NQL.S.E.K.RAAKVIGE.LFMLLQEIGKYC.....
A0A2U3WC28_ODORO/40-178              ..........................................CRLDNSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DKLFHGV...N..A.GE....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PH......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.H.I....E.S...D...D...Q...H..I...Q....R.N...VQM...LKD..T.V..KKL.G.E.N.GEIKAIGE.LNLLFIALKNAC.....
A0A3Q0S6J3_AMPCI/44-174              ............................lrhpqtyqdvrevs---------------------EHAN.D.GEDD..TSMRAM.P.-RVNTDD...H..H.LE....ICCLHANILDYYLTNIL.......H...H.......T........N.......D...D....-......H........TH......MH....R....L...K....TS....LH....RIST.D.LQ.A..Q.G.C....N.V...T...Q...Y...H..D...H....K.N...AVD...FRT..K.L..EKM.E.KkK.GITKAIGE.LDILFSYLQDYC.....
A0A3B4BXF0_PYGNA/21-155              ...........................helrhhfhqirhnml-------------------------.T.EDNQ..KGVRLL.R.GDMMKNL...Q..A.TE....SCCFLRQVLRFYIEKVFn.....tY...T.......S........S.......H...S....L......H........RR......TT....S....V..lA....NS....FL....SISK.D.LQ.A..C.H.V....Q.T...H...C...Q...C..N...A....E.T...MEKsdaIQA..N.Y..NKL.E.PaA.ASAKAIGE.LDSVLEWLE---sf...
G3TXH8_LOXAF/40-178                  ..........................................CRLDKANFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...H..M.SE....HCYLMKQVLNFTLVEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LD....RLSN.K.LS.Q..C.H.I....Q.G...N...D...Q...H..I...Q....T.N...VQK...LKD..T.V..KKL.G.E.I.GEIKAIGE.LGLLFMALRNAC.....
A0A2K6BGF3_MACNE/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.S.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A498M1M7_LABRO/28-166              .................................kpldssvtw--------------NDLFLMTKHAQ.M.EDTD..HETRLL.P.VISEVML...K..E.EN....SCCVNAMILNYYLKHIL.......H...Ad.....eQ........V.......D...K....K......Y........PH......IR....F....V...R....SD....LQ....RIAH.V.LKpH..C.E.S....T.D...F...A...D...HarV...K....E.F...ETN...YKT..A.S..AQE.Y.E.K.TRNKAVGE.TIILFHYLFESC.....
L9L0Z1_TUPCH/39-177                  ..........................................CKLNKSNFQQAYIINRTFMLAKEAN.S.ADNN..TEVRLI.G.EKLFRGV...N..M.GE....RCYLMKQVLNFTLEEVF.......F...P.......N........S.......D...R....F......Q........PY......MQ....E....V...I....SF....LD....RLRN.K.LS.S..C.H.I....E.G...D...D...Q...H..I...Q....N.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.VNLLFMKMKEVC.....
A0A3P8U4A6_AMPPE/68-184              .................eedasfrlmprfshdhtmtfsqdql-------------------------.-.----..------.-.-------...-..-.-K....ICCLHANILDFYLHNIL.......-...R.......H........A.......D...N....M......H........PS......MH....R....L...R....TD....LH....RVSQ.D.LK.D..H.G.C....N.V...T...H...Y...H..D...H....Q.H...AVE...FRE..K.L..AKMdG.E.R.GITKAIGE.IDILFAYLQDSC.....
A0A2K5JUR6_COLAP/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...G...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A2K5ZZP7_MANLE/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
F6ZMP3_MONDO/36-155                  ..........................................CKLPKSEFHLNEISNQIVNMSQMAS.L.EDMD..TSTRFI.D.SSLFQDV...A..T.VD....RCYVMKLVLDFALSEGV.......K...P.......Y........G.......D...K....F......Q........PY......TQ....H....V...F....NF....LT....SLKS.K.LS.K..C.V.M....K.F...D...N...I...H..V...L....E.K...IAA...MKN..K.L..KQV.-.-.-.--------.------------lity.
M3Z1D7_MUSPF/39-177                  ..........................................CRLANSDFEQPYITNRTFMLAGEAS.L.ADNN..TDVRLI.G.DTLFHGV...N..K.ED....HCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...E....SF....LT....KLSN.R.LS.Q..C.H.I....D.S...D...D...Q...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.D.GEIKAIGE.LNLLFIALRDAC.....
IL22B_MOUSE/40-178                   ..........................................CKLEVSNFQQPYIVNRTFMLAKEVS.L.ADNN..TDVWLI.G.EKLFRGV...S..A.KD....QCYLMKQVLNFTLEDVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LT....KLSN.Q.LS.S..C.H.I....S.G...D...D...Q...N..I...Q....K.N...VRR...LKE..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A087X710_POEFO/55-177              ..............................gklsahaqrkel-------------------------.-.-EED..TSIRLM.P.-RVNTDQ...N..H.ME....ICCLHANILNFYLNNIL.......H...K.......Y........S.......E...E....-......H........PS......MH....K....L...Q....TD....LH....RVSS.D.LQ.T..Q.G.C....N.V...T...H...Y...H..N...H....R.H...AVE...FRR..K.L..ERMeG.E.R.GINKAVGE.IDILFTYLHDFC.....
R0KSK0_ANAPL/46-184                  ..........................................CRLRKTNFQQHYIRNRTYTLAKMVQ.A.SDQD..TDNRLI.G.QQLYINI...K..E.NN....RCYMMKRIVEIIVKDVL.......L...T.......E........A.......R...E....K......Y........PY......TE....E....V...A....QF....LA....SLTS.E.LS.R..C.K.F....S.G...N...R...E...H..I...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKNKAIGE.LDLLFDYVENAC.....
A0A2K5DDQ0_AOTNA/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....SF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A3B5B6F7_9TELE/80-177              ...................................rpsdqlk-------------------------.-.----..------.-.-------...-..-.--....ICCLHANILDFYLHNIL.......-...R.......Q........S.......D...N....L......H........PS......MH....R....L...R....TD....LH....RVSQ.D.LQ.T..H.G.C....N.V...T...H...Y...H..D...H....Q.H...AVE...FRK..K.L..ATMdG.N.R.GITKAVSE.IDILFSYLQDTC.....
A0A2Y9G2H0_TRIMA/40-178              ..........................................CRLDKANFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLT.G.EKLFHGV...H..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LD....RLSN.K.LS.Q..C.H.I....Q.G...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LGLLFMALRNAC.....
A0A3B4Y1R6_SERLL/42-178              ...................................sqplrnp---------QTYQAVRDISQHAQSQ.Q.TDDD..SSSRLM.P.RVTNTNQ...D..H.LK....ICCLHANILDFYLNNIL.......-...R.......H........R.......D...N....Q......H........PS......MH....R....L...K....TD....LS....RVSE.D.LK.T..Q.G.C....N.V...T...H...Y...H..D...H....H.H...AVE...FRR..K.L..AMMgG.E.Q.GMNKAMGE.IDILFTYLQDFC.....
A0A3Q1C1K4_AMPOC/80-184              .............................shdhtmtfsqdql-------------------------.-.----..------.-.-------...-..-.-K....ICCLHANILDFYLHNIL.......-...R.......H........A.......D...N....M......H........PS......MH....R....L...R....TD....LH....RVSQ.D.LK.D..H.G.C....N.V...T...H...Y...H..D...H....QhA...VEF...RKK..L.A..KMD.G.E.R.GITKAIGE.IDILFAYLQDSC.....
A0A226MP71_CALSU/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAEMAR.V.SDQD..TDNRLI.G.QHIYINI...K..E.NN....RCYMMKRIAEIILKDVL.......L...T.......E........A.......K...E....R......Y........TL......AE....D....V...A....QF....LA....SLTS.E.LS.R..C.K.H....S.G...N...R...E...H..I...E....K.N...LEE...MKS..K.M..EEL.G.E.N.GKNKAIGE.LDLLFDYIENAC.....
A0A402EN16_9SAUR/48-147              ......................................nlns--------------------AGPAR.L.YDND..TDNRFV.G.QHLYINI...K..E.KN....HCYVMKRVTEVVLKNIL.......-...S.......E........L.......R...N....Q......Y........PM......IE....D....V...A....NF....LG....LLHK.E.LS.K..C.K.P....L.G...H...K...E...H..I...E....N.N...LEK...MKD..K.M..KQV.-.-.-.--------.------------y....
A0A2K6UL79_SAIBB/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDIRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....SF....LA....RLSN.R.LS.T..C.Y.I....E.G...D...D...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A340XU04_LIPVE/40-178              ..........................................CRLDRANFHQPYITNRTFALAHEAS.L.ADNN..TDVRLI.G.TKLFQGV...K..M.ME....RCYMLKQVLNFTLEEVL.......L...P.......Q........S.......N...R....F......K........PY......MQ....E....V...V....PF....LA....RLNK.K.LG.Q..C.H.M....E.C...D...N...Q...N..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKVIGE.LNLLFMALKNEC.....
A0A0D9QWD6_CHLSB/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A2J8W0T4_PONAB/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
L5JVH5_PTEAL/40-178                  ..........................................CRLDKSNFQQPYITNHTFMLAKEAR.S.ADNN..TDVRLI.G.EKLFRGV...H..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.K.LS.Q..C.H.I....K.S...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMTLRNVC.....
H0Z8L5_TAEGU/43-181                  ..........................................CRLRKINFQQPYIRNRTYTLAKTAS.A.SDTD..TDNRLI.G.QQLFVNI...R..E.NN....RCYMMKRVVELVVKDVL.......L...A.......E........V.......K...N....Q......Y........PY......VE....Q....V...A....QF....LA....SLTS.E.LS.G..C.Q.F....L.G...K...R...D...H..I...E....K.N...LEQ...MKN..K.M..EQL.G.E.N.GKLKAIGE.LDLLFDYMENAC.....
A0A3B3CRV8_ORYME/36-167              .....................dpktgqavvevaqhaqkkele-------------------------.-.--AD..TNIRLL.P.-RVNGSQ...D..H.LK....ICCLHANILDFYLNNIL.......H...G.......H........R.......D...D....A......H........PS......MH....R....L...K....TD....LH....RISE.D.LQ.S..Y.G.C....N.V...T...H...Y...H..D...H....R.H...AVE...FRR..K.L..EKMeG.E.R.GLNKAVGE.IDILFTYLQDHC.....
G3TAL5_LOXAF/36-180                  ...............................crvqgvelqgl-------------RRAFWTMKDTVQ.A.QDHN..TSVRLL.R.KEILQNI...S..D.AE....SCYFIHSLLGFYMKTVFk....nyY...N.......K........A.......N...D....L......Ki......lQS......FS....T....L...A....NN....FI....VISS.K.LQ.P..S.E.E....N.E...M...F...S...V..IksaH....R.Q...FLQ...FQV..A.F..KKL.DiE.A.ALTKALGE.LDILLTWME---ky...
M7BDI3_CHEMY/362-489                 ...............................ylvksfhrghi----------------------LAS.L.SDQD..TDNRLI.G.QQLYINV...Q..E.TN....RCYVMKRVIEIIVNEVL.......L...S.......V........T.......S...N....R......Y........PY......IH....E....V...A....QF....LA....ALST.E.LS.G..C.K.F....S.G...H...R...E...H..V...E....K.N...LEE...MKD..K.I..KQL.G.V.S.GKNKAIGE.LDLLFDYLENAC.....
A0A2K6PCP6_RHIRO/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGI...S..T.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A2Y9E3G0_TRIMA/40-178              ..........................................CRLDKANFQQPYITNRTFMLAKEAS.F.ADNN..TDVRLI.G.EKLFHGV...H..M.SE....RCYLMKLVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LD....RLSN.K.LS.Q..C.H.I....Q.G...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.S.GGIKAIGE.LDLLFMALRNAC.....
A0A2I0MJX1_COLLI/45-183              ..........................................CRLRKINFQQPYIRNRTYTLAKMAR.V.SDQD..TDNRLI.G.QQLYANV...K..E.NN....RCYMMKRIVEIVVTDVL.......L...T.......K........V.......K...D....Q......Y........PY......VE....E....V...A....HF....FA....SLNS.E.LS.R..C.K.F....S.G...N...R...E...H..I...E....R.N...LEE...LKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYTENAC.....
L5JVE0_PTEAL/32-181                  ..........................................CRVKGVDFQELWEAFQ--AMKDIVQ.A.QDNI..TSIRLL.R.REVLQNV...S..D.TE....SCYLIRALLKFYLNTVF.......K...Sy....heK........A.......A...E....FrilksfS........TL......AN....N....F...I....FI....AS....KLQP.S.VS.R..T.K.LgpgpR.G...N...I...E...S..A...R....R.R...FLL...FQR..A.F..KQL.DiE.A.AQTKAFGE.VDILLTWMQ---kf...
A0A091IK75_CALAN/46-184              ..........................................CKLSKTHFQPPYIRNVTYTLAKMAK.A.SDHD..TDNRFI.G.QQLFVNI...K..E.NN....RCYMMKRVVEIVVKDVL.......-...A.......E........A.......K...K....L......Y........PN......AE....K....V...A....EF....FA....RLTKeE.LR.S..C.N.S....S.G...H...K...E...P..I...E....K.N...LGE...MKN..K.M..KQL.G.D.N.GKTKAIGE.LDLLFDYTEDAC.....
A0A3Q2DF17_CYPVA/47-174              .........................mhkdvlevsheaqrkel-------------------------.-.-EED..TSIRLM.P.-RVNHTQ...N..H.ME....ICCLHANILNFYLNNIL.......H...K.......Y........S.......S...E....-......H........PN......MD....R....L...K....TN....LH....RVSE.D.LQ.T..Q.G.C....N.L...T...H...Y...H..D...H....R.H...TVE...FRR..K.L..ERM.E.DqR.GINKAVGE.TYILFTYLHDYC.....
A0A2Y9E4Y0_TRIMA/40-178              ..........................................CRLDKANFQQPYITNRTFMLAKEAG.L.ADNN..TDVRLI.G.EKLFHGV...H..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LD....RLSN.K.LS.K..C.H.I....Q.G...N...D...Q...H..I...Q....R.N...MQT...LKD..A.V..KKL.G.E.S.GEIKAIGE.LGLLFMALRNAC.....
A0A2Y9EQJ2_PHYMC/40-178              ..........................................CLLDRANFQQPYITNRTFALAHEAS.L.ADNN..TDVRLI.G.TKLFQGV...N..M.ME....RCYTLKQVLNFTLEEVL.......F...P.......Q........S.......N...R....F......K........PY......MQ....E....V...V....PF....LA....RLNK.K.LG.Q..C.H.I....E.R...D...N...Q...N..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKVIGE.LNLLFMALKNEC.....
A0A3L8SQ08_CHLGU/43-181              ..........................................CRLRKINFQQPYIRNRTYTLAKMAS.A.SDKD..TDNRLI.G.QQLFVNI...R..E.NN....RCYMMKRVVELVVKDVL.......L...T.......E........V.......K...N....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LS.G..C.Q.F....S.G...K...R...D...H..I...E....K.N...LEQ...MKN..K.M..EQL.G.E.N.GKTKAIGE.LDLLFDYMENAC.....
A0A093QGF7_9PASS/41-179              ..........................................CRLRKINFQQPYIRNRTYTLAKMVH.A.SDKD..TDNRLI.G.QQLYVNI...K..E.NN....RCYLMKRVVEIVVKDVL.......L...T.......E........V.......K...N....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LG.R..C.K.F....S.G...N...R...E...H..I...E....K.N...LEQ...MKN..K.M..EQL.G.E.N.GKTKAIGE.LDLLFDYMENAC.....
M3WMS8_FELCA/40-178                  ..........................................CRLDGSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFYEV...N..M.GE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.K.LS.Q..C.H.I....D.S...D...D...Q...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.N.GEIKVIGE.LDLLFMALRNAC.....
A0A3Q3LW29_9LABR/47-179              ..............................lhspetydmvhk-------------------VAQHAQsLqTEDD..SSVRLI.P.-RVNTNE...D..H.LK....ICCLHANILDFYLNNIL.......R...-.......H........H.......Q...N....A......H........PR......MN....Q....L...E....TD....LS....RVSL.D.LQ.N..Q.G.C....N.V...T...H...Y...H..D...H....HhA...VEF...VKK..L.K..KME.G.G.R.GIIKAVGE.IDILFTYLQDFC.....
G1NYG9_MYOLU/40-178                  ..........................................CKLNESDFLPSYFTNRTFRMAEEVS.L.LDNN..TDVSLI.G.KKLYHGV...N..E.NE....HCYVMKQVLNFTLEEVL.......I...P.......E........S.......D...R....F......Q........PY......MK....E....V...V....SF....LK....KLSN.K.LS.Q..C.H.I....E.N...D...D...E...H..I...H....R.N...VQK...LKD..T.V..KEL.G.E.S.GKIKAIGE.INLLFMFLQEAC.....
A0A3B3QJT2_9TELE/27-167              ........................kqksehrsppldnhstfq---------------RISEIAKTAQ.E.MDDD..HETRLIqS.EKHYRNE...T..D.LF....VCCLHANILDFYLGNVL.......N...T.......E........-.......-...E....K......F........PD......LA....T....V...K....TD....LD....RISR.D.LT.VkgC.S.I....K.H...V...N...D...H..G...H....S.N...--K...FKE..S.F..HKM.G.K.R.AQTKAMGE.IDILFDFLAKFC.....
A0A091WZ26_OPIHO/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAKMVQ.V.SDQD..TDNRFI.G.QQLYVNV...R..E.NN....RCYMMKRIVEIVVKDVL.......L...T.......E........V.......K...D....R......Y........PY......VG....E....V...A....QF....LA....SLTS.E.LS.R..C.K.F....S.G...Q...K...E...H..M...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYIENAC.....
H3A664_LATCH/45-187                  ......................................scki------AKSPPHIGKITYTLAKWAQ.R.SDAD..TVTRLI.DpKSLFSNK...L..E.ED....HCYQMKEVLNYLLQQVL.......M...N.......S........S.......E...A....Qap.aveY........PH......LR....D....V...L....EF....FA....KLSE.D.LT.D..C.K.L....K.G...D...K...K...G..I...E....S.N...MEV...LKD..K.I..KKL.G.E.S.ARNKAIGE.LDQLLDTTLKV-c....
A0A2K6GJ76_PROCO/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.RE....RCYLMKQVLNFTVEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.K.LS.P..C.H.I....E.G...D...D...Q...H..I...Q....R.N...VQQ...LKD..T.V..EKL.G.E.S.GEIKAIGE.LDLLFMALRNAC.....
A0A2U3ZLF9_ODORO/40-178              ..........................................CRLDNSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DKLFHGV...N..V.RE....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PH......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.H.I....E.S...D...D...Q...H..I...Q....R.N...VQM...LKD..T.V..KKL.G.E.N.GEIKAIGE.LNLLFIALKNAC.....
A0A060XIV4_ONCMY/36-170              .......................tvhthelrkhyteirssvi-------------------------.A.ADSQ..MGVRLL.R.GDVMRNI...Q..E.GE....YCCFLRLLLRFYVERVF.......V...S.......H........G.......M...-....S......Q........PL......HR....R....S...T....SA....LAnsflTINK.D.LR.Q..C.H.C....H.C...G...E...-...D..T...R....R.K...MDS...LQA..Q.F..DKL.EiY.Q.AAVKAIGE.LDSLLDWLE---el...
A0A3Q1JG59_ANATE/35-170              .................sqplrnpdtynavrvvsqhaqslqt-------------------------.-.-EDD..SSTRLM.-.PRVNTDQ...D..H.LK....ICCLHANILDYYLRNIL.......-...S.......H........S.......N...N....D......H........PH......MH....R....L...K....TD....LT....RVSE.D.LK.T..Q.G.C....N.V...T...H...Y...H..D...H....H.H...AVE...FRR..K.L..TKMgG.E.K.GINKAVGE.IDILFTYMQDFC.....
H9G878_ANOCA/43-181                  ..................................cvlrtvlp----------SYIKNCTLTIAEQAR.L.SDKD..TDNRFI.G.QHLYANI...K..E.KD....HCYVMKRVTDIIMKNVLs.....eL...K.......S........A.......P...G....Q......Y........SN......VK....E....V...A....NF....LA....ERNG.E.LH.G..C.K.P....S.G...K...N...E...H..I...E....R.N...LKQ...MKD..K.L..DKL.G.E.N.GKNKAVGE.LDLLFEYLVKAC.....
H0VFP5_CAVPO/39-176                  .........................................hCRL--HNFQEPYITNYTFMLAKEAS.F.EDNN..TDVRLI.G.DKLFRGV...N..M.RD....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......ME....Q....V...V....PF....LA....DLSR.K.LS.L..C.H.I....S.G...D...D...Q...H..I...Q....R.N...VQQ...LKD..T.V..KKL.G.E.S.GEIKVIGE.VDLLFMTLKNSC.....
A0A1V4J9R3_PATFA/45-183              ..........................................CRLRKINFQQPYIRNRTYTLAKMAR.V.SDQD..TDNRLI.G.QQLYANV...K..E.NN....RCYMMKRIVEIVVTDVL.......L...T.......K........V.......K...D....Q......Y........PY......VE....E....V...A....QF....FA....SLNS.E.LS.R..C.K.F....S.G...N...R...E...H..I...E....R.N...LEE...LKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYTENAC.....
A0A1U7RPJ3_ALLSI/42-179              ..........................................CKLEKIYFQQPYIRNRTYTLAKEAR.L.LDQD..TENRFI.G.QQLYVNV...K..E.SN....RCYVMKSVLEIIMKEVL.......-...S.......N........L.......K...N....K......N........PH......IH....E....V...I....HF....LE....VLRL.K.LH.G..C.K.F....S.G...H...R...E...H..V...E....R.N...LAE...MKN..R.M..KQL.G.D.N.GKNKAIGE.LDLLFDYMEDAC.....
IL22_MOUSE/40-178                    ..........................................CKLEVSNFQQPYIVNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..A.KD....QCYLMKQVLNFTLEDVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LT....KLSN.Q.LS.S..C.H.I....S.G...D...D...Q...N..I...Q....K.N...VRR...LKE..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A1U7UHM1_TARSY/41-179              ..........................................CSLDRSNFQQPYITNRTFMLAQEAS.L.ADNN..TDVRLI.G.DKLFHGV...N..E.SE....HCYLMKQVLNFTLEEVL.......L...P.......Q........A.......H...R....F......Q........PH......MQ....E....V...L....PF....LA....RLGG.Q.LG.L..C.H.L....E.G...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..RQL.G.E.G.GEIKAIGE.LDLLFMHLMNAC.....
U3IZB0_ANAPP/46-184                  ..........................................CRLRKTNFQQHYIRNRTYTLAKMAR.A.SDQD..TDNRLI.G.QQLYINI...K..E.NN....RCYMMKRIVEIIVKDVL.......L...T.......E........A.......R...E....K......Y........PY......TE....E....V...A....QF....LA....SLTS.E.LS.R..C.K.F....S.G...N...R...E...H..I...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKNKAIGE.LDLLFDYVENAC.....
A0A1S3FC05_DIPOR/40-178              ..........................................CWLDRSQFQQPYIINRTFMLAEEAS.F.ADNN..TDVRLI.G.DKLWQGI...H..G.KR....KCYLMKQVLNFTLEEVL.......F...P.......Y........S.......D...R....F......Q........PY......MQ....D....V...V....HF....LA....RLSS.Q.LN.Q..C.H.I....K.D...D...D...Q...H..I...Q....K.N...VQK...LKD..T.V..KML.G.E.S.GEIKAIGE.VYLLFTALKDAC.....
G3R0Q5_GORGO/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...S..M.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A3B3HWH6_ORYLA/52-179              .........................tsqavlevaqhaqkkel-------------------------.-.-EED..TNVRLL.P.-RVSSNQ...D..H.LK....ICCLHANILDFYLNNIL.......H...H.......-........R.......D...D....A......H........PS......MH....R....L...K....TD....LH....RISE.D.LQ.S..Y.G.C....N.V...T...H...Y...H..D...H....R.H...AVE...FRR..K.L..EKMeG.E.R.GLNKAVGE.IDILFTYLQDHC.....
A0A3Q7WYF1_URSAR/40-178              ..........................................CRLNSSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DQLFHGV...N..M.GD....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.H.I....E.R...D...D...Q...H..I...Q....R.N...VQN...LKD..T.V..TKL.G.E.N.GEIKAIGE.LNLLFIALKNAC.....
A0A091CY89_FUKDA/735-872             ..........................................CMLQKSDFS-TYITNLTFMLAEEAS.F.VDNN..TDVRLI.G.EKLTQGV...K..V.KE....RCYLMKQVLNFTLGEVL.......L...L.......H........A.......D...W....F......Q........PH......ME....E....V...V....SF....LG....GLSN.K.LS.P..C.H.I....K.G...D...D...Q...H..I...Q....R.N...VQQ...LKD..T.V..KKL.G.E.S.GEIKAISE.VNLLLMYLNNYC.....
A0A1U7R863_MESAU/41-179              ..........................................CKLDVSNFQRPYFTNRTFKLAEEAS.L.ADNN..TDVRLI.G.DELFQGV...N..R.QN....RCYLMKQVLNFTLAEVL.......I...P.......H........S.......D...R....F......Q........PY......MQ....Q....V...V....PF....LT....KLSN.Q.LS.L..C.Q.I....R.G...D...G...Q...H..I...Q....K.N...IQT...LKE..T.V..KQL.G.E.S.GEIKAIGE.LNLLFMHLRNYC.....
F7DY14_HORSE/40-178                  ..........................................CRLDESDFQQPYIINRTFKLADEAS.L.ADNN..TDVRLI.G.EKLFHGV...N..V.RQ....HCYLMKQVLNFTLEEVL.......L...P.......Y........S.......D...R....F......Q........PY......MQ....E....V...V....SF....LA....GLSN.K.LS.Q..C.H.I....E.G...D...D...Q...H..V...Q....K.K...VQN...LKD..T.V..KKL.G.E.S.GDIKAIGE.LNLLFMRLKNAC.....
F6PQU9_ORNAN/41-184                  ..........................................CRLKNSDFEVSFINQRILNLSKKAS.D.QDTI..TDIRLI.N.STFPQDV...Q..V.GD....RCYLMKQILNFTLEVVI.......P...P.......Q........Y.......T...Q....L......M........PF......IQ....D....V...E....SF....FS....DLHR.K.LR.Y..C.V.S....V.F...T...PtlwE...S..L...P....L.L...LRV...LPT..L.LsqEPL.G.K.K.GMNKVIGE.LNLLFMALKHAC.....
A0A2K6MV29_RHIBE/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
E2R2K7_CANLF/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...N..M.GE....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.K.LS.Q..C.H.I....E.N...D...D...Q...H..I...Q....R.N...VQK...LKD..T.V..QKL.G.E.N.GEIKAIGE.LDLLFMALRNAC.....
A0A2R8ZS67_PANPA/40-178              ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFHGV...S..M.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQK...LKD..T.V..KKL.G.E.N.GEIKAIGE.LDLLFMSLRNAC.....
F6WL87_CALJA/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....SF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A3Q1G8C2_9TELE/67-184              ................teedasfrltprltndhtvafsqdql-------------------------.-.----..------.-.-------...-..-.-K....ICCLHANILDFYLHNIL.......-...R.......H........A.......D...N....M......H........PS......MH....R....L...R....TD....LH....RVSQ.D.LK.G..H.G.C....N.V...T...H...Y...H..D...H....Q.H...AVE...FRK..K.L..AQMdP.E.R.GITKAIGE.IDILFAYLQDSC.....
A0A3B4AVD4_9GOBI/37-175              ................................hrsfspplrn--------------PETYKAVNKVS.Q.HAQD..NSVDDT.G.SRLIPRV...D..T.EEdhlkICCLHANILDFYLRNI-.......L...P.......R........H.......D...N....K......H........PH......MH....R....V...R....TD....LQ....RVSE.D.LK.T..Q.G.C....N.V...T...H...Y...H..D...H....R.H...AVQ...FRK..K.L..AEM.G.EeQ.GINKAVGE.INILFSYLQDFC.....
A0A3B3RN56_9TELE/38-177              ..................................vtvhtyem--------------RRDFTEMRQIM.VnEDKH..ISTRLI.S.KQTMKEL...Q..P.LE....SCCFLKQLLSFYVERVFs....syV...P.......N........Q.......S...Q....F......R........RN......TS....N....L...A....NS....FL....SIRN.D.LL.K..C.Q.E....E.M...R...C...EcgaD..S...E....A.R...LAT...IHA..N.Y..EKL.EpR.D.GAVKAIGE.LDSLLEWME---ty...
A0A226P0Q4_COLVI/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAEMAR.V.SDQD..TDNRLI.G.QHIYINI...K..E.NN....RCYMMKRIAEIILKDVL.......L...T.......E........A.......K...E....W......Y........PL......AE....D....V...A....QF....LA....SLTS.E.LS.R..C.K.H....S.G...N...R...E...H..I...E....K.N...LEE...MKS..K.M..KEL.G.E.N.GKNKAIGE.LDLLFDYIENAC.....
A0A091G7B7_9AVES/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAKMVQ.V.SDHD..TDNRLI.G.QQLYVNV...R..E.NN....RCYLMKRIAELVVKDVL.......L...T.......T........A.......K...D....R......Y........PY......VE....E....V...A....QF....LA....SLTL.E.MS.R..C.K.F....S.G...H...R...E...H..I...E....K.N...LEE...MKN..K.M..KQL.G.E.N.GKIKAIGE.LDLLFDYMENAC.....
A0A218V425_9PASE/1-88                ..........................................-------------------------.-.----..------.-.-------...-..-.--....---MMKRVVELVVKDVL.......L...T.......E........V.......K...N....Q......Y........PY......VD....Q....V...A....QF....LA....SLTS.E.LS.G..C.Q.F....S.G...K...R...D...N..I...E....K.N...LEQ...VKN..K.M..EQL.G.E.N.GKTKAIGE.LDLLFDYMENAC.....
A0A2K5NDW2_CERAT/40-176              ..........................................CRLDKSNFQQPYIPT--SFLLFQAS.L.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A452RY20_URSAM/40-178              ..........................................CRLNSSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DQLFHGV...N..M.GD....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.H.I....E.R...D...D...Q...H..I...Q....R.N...VQN...LKD..T.V..TKL.G.E.N.GEIKAIGE.LNLLFIALKNAC.....
A0A2U3V8J7_TURTR/40-178              ..........................................CRLDRANFQQPYITNRTFALANEAS.L.VDNN..TDVRLI.G.TKLFQGV...K..M.ME....RCCMLKQVLNFALEEVL.......L...P.......Q........S.......N...R....F......K........PY......MQ....E....V...V....PF....LA....RLNK.K.LG.Q..C.H.M....E.C...D...N...Q...N..I...Q....R.N...VQN...LKD..T.V..KKL.G.E.S.GEIKVIGE.LNLLFMALKNEC.....
U3K667_FICAL/43-183                  ..........................................CRLRKINFQQPYIRNRTYTLAKTAS.A.SDKD..TDNRLI.G.QQLFVNI...RtkE.NN....RCYLMKRVVEFVVEDVL.......L...T.......E........V.......K...N....Q......Y........PH......VE....E....V...A....QF....LA....SLTS.E.LR.S..C.Q.F....S.G...K...K...E...H..I...E....K.N...LEQ...MKN..K.M..EQL.G.E.N.GKTKAIGE.LDLLFDYMENAC.....
F6YBU5_MACMU/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.S.ADNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.S.LS.T..C.H.I....E.G...D...D...L...H..I...Q....K.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A091EPC6_CORBR/43-181              ..........................................CKLRKINFQQPYIRNRTYTLAKTVH.A.SDKD..TDNRLI.G.QQLFVNI...K..E.NN....RCYLMKRVVEFVVKDVL.......L...T.......E........V.......K...Y....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LS.S..C.K.F....S.G...Q...K...E...H..I...E....K.N...LEQ...MKK..K.M..EQL.G.E.N.GKTKAIGE.LDLLFDYMENAC.....
A0A1S3P5V7_SALSA/34-170              .....................svtvhthelrkhyteirssvi-------------------------.A.ADSQ..MGVRLL.R.GDMMSNI...Q..E.GE....HCCFLRLLLRFYVERVF.......V...S.......H........G.......-...L....S......Q........PL......HR....R....S...T....SA....LAnsflTINK.D.LR.H..C.H.C....H.C...G...E...-...D..T...R....R.K...MDS...LQA..Q.F..DKL.EiY.Q.AAVKAIGE.LDSLLDWLE---el...
G1NDB2_MELGA/46-184                  ..........................................CRLRKINFQRPYIRNRTYTLAEMAR.V.SDQD..TDNRFI.G.QQIYVNI...R..E.NN....RCYMMKRITEIILKDVL.......L...T.......E........A.......K...E....R......Y........PY......AE....D....V...A....QF....LA....SLTS.E.LG.R..C.K.Y....S.G...N...R...E...H..I...E....K.N...LEE...MKS..K.M..KEL.G.E.N.GKNKAIGE.LDLLFDYIENAC.....
I3M7Y2_ICTTR/36-179                  ..........................................CRAEGVNLQQ--LREAFWTIQETVQ.A.QDNT..TSVRLL.R.QEVLQNV...S..D.AE....SCYLIHALLKFYLNTVF.......K...N.......Y........H.......K...R....A......EfktlksfsTL......AN....N....F...I....VI....MS....KLQP.S.QE.N..E.M.F....-.S...V...S...E...S..A...H....K.R...FLL...FHR..A.F..KRL.DiE.A.ALTKALGE.VDILLTWME---kf...
A0A3M0KBX0_HIRRU/488-626             ..........................................CRLRKINFQQPYIRNRTYTLAKTAS.A.SDKD..TDNRLI.G.QQLFVNI...R..E.NN....RCYLMKRVVEFVVKDVL.......L...T.......E........V.......K...N....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LS.S..C.Q.F....S.G...R...R...E...H..I...E....K.N...LEQ...MKN..K.M..AQL.A.E.N.GKTKAIGE.LDLLFDYMENSC.....
G3V6X6_RAT/40-178                    ..........................................CKLEAANFQQPYIVNRTFMLAKEAS.L.ADNN..TDVRLI.G.EELFRGV...K..A.KD....QCYLMKQVLNFTLEDVL.......L...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LT....KLSS.H.LS.P..C.H.I....S.G...D...D...Q...N..I...Q....K.N...VRQ...LKE..T.V..QKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A5JS75_BOVIN/40-179                  ..........................................CRLNESDFQEPYIFNHTFTLAQKAS.L.ADNI..TDVRLI.G.NKLFHGI...H..QvTK....RCYVLKQVLNFILEEVL.......F...P.......Q........S.......D...K....F......H........PY......ME....K....V...V....PF....FS....RLSK.K.LS.Q..C.H.V....E.S...D...N...Q...H..I...Q....R.N...VQN...LKN..T.V..KKL.G.E.S.GEIKVIGE.LNLLFTTLKREC.....
A0A3Q4HMR6_NEOBR/52-176              ............................dvgqvsehvndedd-------------------------.-.-EDD..TSMRVI.P.-RVNTND...H..H.FE....ICCLHANILDYYLTNIL.......H...H.......-........T.......N...N....D......H........AH......MH....R....L...K....TN....LH....RIST.D.LQ.A..H.G.C....N.V...T...Q...Y...H..D...H....K.N...AVD...FRT..K.L..EKM.E.KmK.GITKAISE.LDILFSYLQDYC.....
G1QTK0_NOMLE/40-178                  ..........................................CRLDKSNFQQPYITNRTFMLAKEAS.L.VDNN..TDVRLI.G.EKLFRGV...S..M.SE....RCYLMKQVLNFTLEEVL.......F...P.......Q........S.......D...R....F......Q........PY......MQ....E....V...V....PF....LA....RLSN.R.LS.T..C.H.I....E.G...D...D...L...H..I...Q....S.N...VQK...LKD..T.V..KKL.G.E.S.GEIKAIGE.LDLLFMSLRNAC.....
A0A2U3Y8K1_LEPWE/40-178              ..........................................CRLNHSDFQQPYITNRTFMLAEEAS.L.ADNN..TDVRLI.G.DKLFHGV...N..V.RE....RCYLMKEVLNFTLEEVL.......L...P.......Q........S.......H...R....F......Q........PY......MQ....E....V...V....PF....LA....KLSN.R.LS.Q..C.R.I....E.S...D...E...Q...H..I...Q....R.N...VQM...LKD..T.V..KKL.G.E.N.GEIKAIGE.LSLLFIALRNAC.....
A0A4D9ED44_9SAUR/15-153              ..........................................CRLRKISFQQSYIRNRTYTLAKLAR.L.SDQD..TDNRLI.G.QQLYINV...Q..E.TN....RCYVMKRVIEIVVDEVL.......L...S.......V........P.......R...N....R......Y........PH......IH....E....V...A....QF....LA....ALST.E.LS.G..C.K.F....S.G...H...R...E...H..V...E....K.N...LEE...MKD..K.M..KQL.G.V.S.GKNKAIGE.LDLLFDYMENAC.....
G5BGB6_HETGA/40-177                  ..........................................CVLKKSDFS-TYITNLTFMLAEEAS.F.ADNN..TDVRLI.G.GKLVRGV...N..V.KE....RCYLMKQVLNFTLEEVL.......F...P.......H........S.......D...W....F......Q........PH......MK....E....V...V....SF....LD....GLSN.K.LS.P..C.H.I....R.G...D...D...Q...H..I...Q....R.K...VEQ...LKD..T.V..KKL.G.E.S.GDIKAISE.VNLLLSYLKDYC.....
K7GEW3_PELSI/42-180                  ..........................................CRLRKINFQQAYIRNRTYTLAKLAR.L.SDQD..TDNRLI.G.QQLYINV...Q..E.TN....RCYVMKKVVKIIVDEVL.......L...P.......A........P.......K...N....Y......Y........PH......IH....E....V...A....QF....LA....ALTT.E.LS.G..C.K.F....S.G...H...R...E...H..I...E....R.N...LEQ...MRD..K.I..KQL.G.Q.S.GKNKAIGE.LDLLFDYMENAC.....
A0A0A0APS8_CHAVO/46-184              ..........................................CKLRKINFQQPYIRNRTYTLAKMVQ.V.SDED..TDNRLI.G.QQIYVNV...K..E.NN....RCYMMKRIAEIVVEDVL.......L...T.......E........T.......K...D....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LS.R..C.K.F....S.G...H...R...E...H..I...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYIENAC.....
A0A091UXW4_NIPNI/46-184              ..........................................CRLRKINFQQPYIRNRTYTLAKMVQ.V.SDQD..TDNRFI.G.QQLYVNI...K..E.NN....RCYMMKRIVEIVVKDVL.......L...T.......E........A.......K...D....Q......Y........PY......VE....E....V...A....QF....LA....SLTS.E.LS.A..C.K.F....T.G...H...R...E...H..I...E....K.N...LEE...MKS..K.M..KQL.G.E.N.GKTKAIGE.LDLLFDYIENAC.....
#=GC SS_cons                         ..........................................S---GGGG-SHHHHHHHHHHHHHHH.H.TSTT..TSS-SS.S.GGGGTT-...-..G.GG....HHHHHHHHHHHHHHHTT.......T...T.......T........T.......T...S....S......T........TH......HH....H....H...H....HH....HH....HHHH.H.HT.T..-.-.-....S.S...-...S...H...H..H...H....H.H...HHH...HHH..H.H..HHT.H.H.H.HHHHHHHT.HHHHHHHHHHHH.....
#=GC seq_cons                        ..........................................C+Lpp.sFQpsYIpNRTahLAcpAp.h.uDss..TDsRLI.G.pcLapsl...p....s-....RCYLMKpVLsFhLc-VL.......h...s.......p........u.......c...c....h......p........Pa......Mp....-....V...s....sF....Lu....+LSs.c.LS.p..C.+.h....p.u...c...c...p...H..I...p....+.N...lpp...hKc..p.l..++L.G.E.s.GchKAIGE.LDLLFhhLcsuC.....
//
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