GenomeNet

Database: Pfam
Entry: IL6
LinkDB: IL6
Original site: IL6 
#=GF ID   IL6
#=GF AC   PF00489.17
#=GF DE   Interleukin-6/G-CSF/MGF family
#=GF PI   IL-6; 
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Prosite
#=GF GA   27.00 27.00;
#=GF TC   27.50 27.20;
#=GF NC   25.80 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Interleukin
#=GF DR   INTERPRO; IPR003574;
#=GF DR   SCOP; 1bgc; fa;
#=GF DR   PROSITE; PDOC00227;
#=GF DR   PRINTS; PR00433;
#=GF DR   HOMSTRAD; cyto;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF SQ   149
#=GS IL6_FELCA/27-208          AC P41683.1
#=GS A0A2I3GA58_NOMLE/26-211   AC A0A2I3GA58.1
#=GS A0A2I3HU53_NOMLE/73-258   AC A0A2I3HU53.1
#=GS A0A0G2JFT1_MOUSE/26-167   AC A0A0G2JFT1.1
#=GS S9YC60_CAMFR/68-173       AC S9YC60.1
#=GS IL6_CHICK/52-233          AC Q90YI0.1
#=GS K7FSQ7_PELSI/22-196       AC K7FSQ7.1
#=GS I3LIB7_PIG/56-241         AC I3LIB7.1
#=GS F6X6K9_HORSE/27-208       AC F6X6K9.1
#=GS A0A1S3Q173_SALSA/81-247   AC A0A1S3Q173.1
#=GS A0A1U8D911_ALLSI/51-236   AC A0A1U8D911.1
#=GS A0A091ELR2_CORBR/1-144    AC A0A091ELR2.1
#=GS G5BB49_HETGA/26-210       AC G5BB49.1
#=GS A0A1U7U6M6_TARSY/27-209   AC A0A1U7U6M6.1
#=GS L8Y536_TUPCH/47-152       AC L8Y536.1
#=GS G1L9D4_AILME/27-211       AC G1L9D4.1
#=GS B4DNV3_HUMAN/1-91         AC B4DNV3.1
#=GS A0A1L8FW11_XENLA/1-130    AC A0A1L8FW11.1
#=GS L9KY14_TUPCH/65-171       AC L9KY14.1
#=GS S7N395_MYOBR/33-214       AC S7N395.1
#=GS S9YC60_CAMFR/27-70        AC S9YC60.1
#=GS IL6_MOUSE/26-211          AC P08505.1
#=GS IL6_MOUSE/26-211          DR PDB; 2L3Y A; 7-190;
#=GS A0A0A0A471_CHAVO/1-144    AC A0A0A0A471.1
#=GS G1PT99_MYOLU/27-208       AC G1PT99.1
#=GS F7CIZ3_MONDO/10-195       AC F7CIZ3.2
#=GS A9JPH4_HHV8/19-192        AC A9JPH4.1
#=GS F7HV62_CALJA/27-212       AC F7HV62.1
#=GS A0A091PQH2_LEPDC/1-144    AC A0A091PQH2.1
#=GS I3LIW9_PIG/6-191          AC I3LIW9.1
#=GS IL6_BOVIN/27-208          AC P26892.1
#=GS A0A2K5KAT3_COLAP/27-164   AC A0A2K5KAT3.1
#=GS A0A091PFU6_HALAL/1-143    AC A0A091PFU6.1
#=GS G3USN5_MELGA/1-118        AC G3USN5.1
#=GS A0A087R7D0_APTFO/1-144    AC A0A087R7D0.1
#=GS A0A0D9RN63_CHLSB/27-212   AC A0A0D9RN63.1
#=GS A0A091D1V2_FUKDA/26-210   AC A0A091D1V2.1
#=GS A0A226P4Q5_COLVI/50-139   AC A0A226P4Q5.1
#=GS A0A0G2JGF4_MOUSE/26-162   AC A0A0G2JGF4.1
#=GS A0A093IED3_EURHL/1-144    AC A0A093IED3.1
#=GS A0A2I4B000_9TELE/104-213  AC A0A2I4B000.1
#=GS H3AI47_LATCH/2-148        AC H3AI47.1
#=GS G3UHF3_LOXAF/20-205       AC G3UHF3.1
#=GS I3J0Y3_ORENI/34-208       AC I3J0Y3.1
#=GS A0A2I3LHM9_PAPAN/29-214   AC A0A2I3LHM9.1
#=GS A0A2I3SUM2_PANTR/49-234   AC A0A2I3SUM2.1
#=GS A0A1V4KBZ6_PATFA/1-142    AC A0A1V4KBZ6.1
#=GS U3K550_FICAL/1-157        AC U3K550.1
#=GS A0A1U7QW01_MESAU/26-212   AC A0A1U7QW01.1
#=GS F6YS54_ORNAN/23-154       AC F6YS54.1
#=GS G3NRW1_GASAC/65-205       AC G3NRW1.1
#=GS A0A1A6GRC6_NEOLE/113-298  AC A0A1A6GRC6.1
#=GS A0A218VED9_9PASE/1-43     AC A0A218VED9.1
#=GS A0A2K5KAQ8_COLAP/29-214   AC A0A2K5KAQ8.1
#=GS IL6_MUSPF/27-210          AC A3FBE9.1
#=GS VIL6_HHV8P/27-193         AC Q2HRC7.1
#=GS G1TX17_RABIT/1-144        AC G1TX17.1
#=GS A0A2K5KAS8_COLAP/27-212   AC A0A2K5KAS8.1
#=GS IL6_MACMU/27-212          AC P51494.1
#=GS I3M4W8_ICTTR/20-207       AC I3M4W8.2
#=GS A0A151MQI6_ALLMI/62-170   AC A0A151MQI6.1
#=GS A0A1S2ZSU1_ERIEU/24-210   AC A0A1S2ZSU1.1
#=GS A0A2K5KAS1_COLAP/26-211   AC A0A2K5KAS1.1
#=GS K7FSQ0_PELSI/26-203       AC K7FSQ0.1
#=GS I3N2D4_ICTTR/20-207       AC I3N2D4.2
#=GS F1PXV9_CANLF/22-207       AC F1PXV9.2
#=GS A0A2D0Q0A7_ICTPU/47-192   AC A0A2D0Q0A7.1
#=GS A0A0Q3P9W6_AMAAE/45-227   AC A0A0Q3P9W6.1
#=GS A0A091MIH5_9PASS/1-144    AC A0A091MIH5.1
#=GS A0A091J5E4_EGRGA/1-105    AC A0A091J5E4.1
#=GS M3X721_FELCA/44-225       AC M3X721.2
#=GS H0WPC6_OTOGA/27-211       AC H0WPC6.1
#=GS C9J5B0_HUMAN/27-152       AC C9J5B0.1
#=GS A0A093HHJ7_STRCA/1-147    AC A0A093HHJ7.1
#=GS M7B314_CHEMY/99-206       AC M7B314.1
#=GS I3N090_ICTTR/20-207       AC I3N090.2
#=GS A0A1D5R9U6_MACMU/40-225   AC A0A1D5R9U6.1
#=GS H2TB95_TAKRU/87-208       AC H2TB95.1
#=GS A0A091HXZ8_CALAN/1-144    AC A0A091HXZ8.1
#=GS IL6_SHEEP/27-208          AC P29455.2
#=GS A0A2I3LGB1_PAPAN/27-212   AC A0A2I3LGB1.1
#=GS A0A218VED9_9PASE/49-158   AC A0A218VED9.1
#=GS G7P0R5_MACFA/81-221       AC G7P0R5.1
#=GS A0A0G2JFG1_MOUSE/9-194    AC A0A0G2JFG1.1
#=GS G3QRH2_GORGO/26-211       AC G3QRH2.2
#=GS H2LFW7_ORYLA/93-204       AC H2LFW7.1
#=GS H2QU89_PANTR/27-212       AC H2QU89.1
#=GS A0A091R2R5_MERNU/1-145    AC A0A091R2R5.1
#=GS G1U0P1_RABIT/29-208       AC G1U0P1.1
#=GS IL6_PIG/27-212            AC P26893.2
#=GS A0A2I3FSJ5_NOMLE/27-175   AC A0A2I3FSJ5.1
#=GS A0A091SF61_NESNO/1-144    AC A0A091SF61.1
#=GS A0A093H7M5_DRYPU/1-151    AC A0A093H7M5.1
#=GS G3HVW6_CRIGR/68-174       AC G3HVW6.1
#=GS A0A226P4Q5_COLVI/166-272  AC A0A226P4Q5.1
#=GS G3WCK1_SARHA/22-205       AC G3WCK1.1
#=GS H2PMP3_PONAB/27-212       AC H2PMP3.1
#=GS A0A1S3FSW2_DIPOR/26-213   AC A0A1S3FSW2.1
#=GS V8PIC6_OPHHA/41-171       AC V8PIC6.1
#=GS A0A2K5NHW0_CERAT/29-214   AC A0A2K5NHW0.1
#=GS H3CA23_TETNG/47-201       AC H3CA23.1
#=GS A0A091GA98_9AVES/1-143    AC A0A091GA98.1
#=GS IL6_HUMAN/27-212          AC P05231.1
#=GS IL6_HUMAN/27-212          DR PDB; 4NI9 C; 16-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4J4L C; 19-184;
#=GS IL6_HUMAN/27-212          DR PDB; 2IL6 A; 20-185;
#=GS IL6_HUMAN/27-212          DR PDB; 1P9M B; 19-184;
#=GS IL6_HUMAN/27-212          DR PDB; 5FUC A; 21-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4CNI D; 14-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4NI7 A; 16-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4J4L D; 19-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4ZS7 A; 23-184;
#=GS IL6_HUMAN/27-212          DR PDB; 5FUC B; 21-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4NI9 A; 14-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4CNI C; 14-184;
#=GS IL6_HUMAN/27-212          DR PDB; 1IL6 A; 20-185;
#=GS IL6_HUMAN/27-212          DR PDB; 1ALU A; 19-184;
#=GS IL6_HUMAN/27-212          DR PDB; 4O9H A; 19-184;
#=GS B5MCZ3_HUMAN/5-189        AC B5MCZ3.1
#=GS A0A096NGM9_PAPAN/26-211   AC A0A096NGM9.2
#=GS IL6_HORSE/27-208          AC Q95181.2
#=GS A0A226MNA1_CALSU/50-139   AC A0A226MNA1.1
#=GS R4GCE6_ANOCA/25-210       AC R4GCE6.1
#=GS A0A2I2ZF86_GORGO/14-199   AC A0A2I2ZF86.1
#=GS A0A1D5QRZ4_MACMU/29-214   AC A0A1D5QRZ4.1
#=GS A0A091VT22_OPIHO/1-105    AC A0A091VT22.1
#=GS IL6_CERAT/27-212          AC P46650.1
#=GS IL6_TAKRU/82-203          AC Q6L6X6.1
#=GS F7DMU2_CALJA/27-212       AC F7DMU2.1
#=GS G3HVW6_CRIGR/26-70        AC G3HVW6.1
#=GS A0A2K5NHL6_CERAT/27-212   AC A0A2K5NHL6.1
#=GS A0A2I2ZVU2_GORGO/27-212   AC A0A2I2ZVU2.1
#=GS H9A0J9_DANRE/37-210       AC H9A0J9.1
#=GS G3TFE8_LOXAF/27-212       AC G3TFE8.1
#=GS A0A2I3RKA9_PANTR/26-211   AC A0A2I3RKA9.1
#=GS I3MVL6_ICTTR/13-191       AC I3MVL6.2
#=GS A0A091KK85_9GRUI/1-144    AC A0A091KK85.1
#=GS W5PR13_SHEEP/27-210       AC W5PR13.1
#=GS A0A094KV70_ANTCR/1-105    AC A0A094KV70.1
#=GS B5MC21_HUMAN/1-136        AC B5MC21.1
#=GS A0A1D5QM02_MACMU/27-212   AC A0A1D5QM02.1
#=GS IL6_CANLF/22-207          AC P41323.1
#=GS G3RRX2_GORGO/49-234       AC G3RRX2.2
#=GS IL6_RAT/26-211            AC P20607.1
#=GS L5KPK4_PTEAL/20-202       AC L5KPK4.1
#=GS B5MC14_HUMAN/27-165       AC B5MC14.1
#=GS A0A098GML6_SALSA/35-214   AC A0A098GML6.1
#=GS H3BX13_TETNG/53-202       AC H3BX13.1
#=GS A0A093IZX3_FULGA/1-147    AC A0A093IZX3.1
#=GS IL6_RABIT/28-214          AC Q9MZR1.1
#=GS A0A093PUX7_9PASS/1-144    AC A0A093PUX7.1
#=GS A0A1L8FR84_XENLA/40-211   AC A0A1L8FR84.1
#=GS F6RKC1_XENTR/24-211       AC F6RKC1.1
#=GS A0A226MNA1_CALSU/163-272  AC A0A226MNA1.1
#=GS A0A2I3S6T5_PANTR/14-199   AC A0A2I3S6T5.1
#=GS A0A2K5NI63_CERAT/26-211   AC A0A2K5NI63.1
#=GS A0A087VBL6_BALRE/1-147    AC A0A087VBL6.1
#=GS A0A2K5KAR6_COLAP/7-190    AC A0A2K5KAR6.1
#=GS U3K549_FICAL/23-132       AC U3K549.1
#=GS F7FS80_MACMU/1-136        AC F7FS80.2
#=GS G1S4D6_NOMLE/27-212       AC G1S4D6.1
#=GS H0YWY1_TAEGU/1-144        AC H0YWY1.1
#=GS A0A091W904_NIPNI/1-144    AC A0A091W904.1
#=GS M1F5B2_ANAPL/1-146        AC M1F5B2.1
#=GS A0A2I0MQA2_COLLI/1-142    AC A0A2I0MQA2.1
IL6_FELCA/27-208                     .............................................................PTPGPLGGD----ATSNRLPLTSA..D..KMEELIKYILGKISALKK.E.MCDNYNKCEDSKEALAENN.L.NLPKLAEKDG.C.FQ......S..GF..N..Q....ETCLTRITTG..LQEFQIYLKFL..QDKYEG..DEEN..AKSVYT.STNVLLQ...MLKRKGK....NQ..DEVT.IPVPTVEVGLQAKLQSQ.EEWLRHTTIH.LTLRRLEDFLQFSLRAVRIM.................................
A0A2I3GA58_NOMLE/26-211              .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNRSNMCESSKEALVENN.L.NLPKMAAKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRLES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQYSLRALRQM.................................
A0A2I3HU53_NOMLE/73-258              .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNRSNMCESSKEALVENN.L.NLPKMAAKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRLES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQYSLRALRQM.................................
A0A0G2JFT1_MOUSE/26-167              .............................................................PTSQVRRGDFTEDTTPNRPVYTTS..-..QVGGLITHVLWEIVEMRK.E.LCNGNSDCMNNDDALAENN.L.KLPEIQRNDG.C.YQ......T..GY..N..Q....EICLLKISSG..LLEYHSYLEYM..KNNLKD..NKKD.kARVLQR.DTETLIH...IFNQEVS....A-..----.-----------------.----------.--------------------spslmqcg.........................
S9YC60_CAMFR/68-173                  ............................................................k------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..E....ETCLMRITIG..LLEFQIYLDYL..QNYYEG..DKGN..TEAVQI.STKALIQ...LLRQKVK....QP..EEVS.TPNPITGSSLLNKLQTE.NQWMKNTKMI.LILRSLEDFLQFSLRAVRIM.................................
IL6_CHICK/52-233                     .....................................aadssgevgleeeagarralldce------------------------..-..---PLARVLRDRAVQLQD.E.MCKKFTVCENSMEMLVRNN.L.NLPKVTEEDG.C.LL......A..GF..D..E....EKCLTKLSSG..LFAFQTYLEFI..QETFDS..EKQN..VESLCY.STKHLAA...TIRQMVI....NP..DEVV.IPDSAAQKSLLANLKSD.KDWIEKITMH.LILRDFTSFMEKTVRAVRY-l................................
K7FSQ7_PELSI/22-196                  .......................................dplrnslarspllpdceslawl------------------------..-..--------LHSKAAKLKD.E.MCEKFTVCDNSMEMLAQND.L.NLPKITEEDG.C.LL......S..GF..N..E....EKCLSGISSG..LFTFQTYLEYV..QETLIT..EKQK..VESICY.GTKHLAN...TVRQMVK....NP..GAVI.MPDPATQNTLFAKLKSN.KKWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
I3LIB7_PIG/56-241                    .............................................................PTPGRLEEDAKGDATSDKMLFTSP..D..KTEELIKYILGKISAMRK.E.MCEKYEKCENSKEVLAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..Q....ETCLMRITTG..LVEFQIYLDYL..QKEYES..NKGN..VEAVQI.STKALIQ...TLRQKGK....NP..DKAT.TPNPTTNAGLLDKLQSQ.NEWMKNTKII.LILRSLEDFLQFSLRAIRIM.................................
F6X6K9_HORSE/27-208                  .............................................................PTPLPLGED---ETTSNGPLLTTA..D..KTKQHIKYILGKISALKN.E.MCNNFSKCENSKEVLAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..Q....ETCLMKITTG..LSEFQIYLEYL..QNEFKG..EKEN..IKTMQI.STKVLVQ...ILMQKMK....NP..-EVT.TPDPTAKSSLLAKLHSQ.NEWLKNTTTH.LILRSLEDFLQFSLRAVRIM.................................
A0A1S3Q173_SALSA/81-247              .......................................................ppiwen------------------------..-..-VIKVIKLLVQEVINFRDqQ.FVEEFQKPVEEMSSFIQYQ.VpSIPTHLSKTP.C.ST......S..NY..N..K....EACLQKISHG..LQVYHVLLQHI..KAEYPQ..S-TL..LPSVMH.QTTVLIG...LFKDKMK....VA..EVVE.DLSASERERVLGEVSTG.TEWERKTSVH.AILRELRHFLVDTKKALR--aw...............................
A0A1U8D911_ALLSI/51-236              .....................ssgegdlvdepspsrsspvpdyeslawllrsraarlkheg------------------------..-..-----------------S.G.MCEKFTVCENSMEMLVQSH.L.KLPKILDEDS.C.LQ......S..GF..N..K....EKCLTKISSG..LFAFQPYLEYIhvQETFIS..EKQK..IETIWY.GTKHLAN...TVRQMME....NP..DAVP.IPDQTSQKTLLEKLKAN.KNWREKIATH.FILRDFTSFMEKTVRALRY-i................................
A0A091ELR2_CORBR/1-144               ............................................................q------------------------..-..------------------.-.VCEKFTICPNSMEMLLHNN.L.SLPKVTKEDG.D.FL......T..FL..S.lQ....DKCLRTISSG..LYTFQTYLKYV..QETFIS..ENQN..VESLSY.STERLAR...TIRQMVI....NP..EEVI.IPDAATQESLHTKLKSI.KAWTEKITIQ.LILRDFTSFMEKTVRAVRY-l................................
G5BB49_HETGA/26-210                  .............................................................PTSQVL-KDFRADTTSSKPT-TSN..S..QAFRLFTLVLHDVQELKS.E.TCKHNVNCLEEEKAML-NN.L.NLPKIKIEDG.C.FY......G..GY..N..W....ETCHLKIITG..LLKFQIYLQYM..QNKLQS..DSENekAEKIYT.SVKSLSL...FMKAKVS....NT..EQTV.FPSPTANATLLEELESQ.NETQKLLIVQ.IVLCSLEEFLQNSLRPIRK-a................................
A0A1U7U6M6_TARSY/27-209              ...........................................................pt-TPRPLGEDSTDAAPSNRPSYTTP..E..HIEELIKRILG----LAK.E.MCQKSFGCDNSREVLAGNN.L.NLPKMEKEDG.C.FE......S..GF..N..K....ETCLKKITTG..LLEFQVYLEYL..QNKFEG..NKEH..AETVLI.GTKAMIQ...YLKTKVK....NP..DAVA.TPDPTANAILLVKLKSQ.GQWLQNTTIH.LILRSLIHFLHSSARAIRV-k................................
L8Y536_TUPCH/47-152                  ...........................................................kq------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..E....DTCLMRIITG..LLEFQVYIEFL..KNNVN-..EKSS..ARAVQI.GTKALML...MLKQKET....YP..SIVP.TPDPTSNASLMVKMQSQ.EEWLKKVTVR.LILRSLEDFLQYTVRASRLM.................................
G1L9D4_AILME/27-211                  .............................................................PTPGHLGRDSKDEATSNRPPLISA..D..KME-IIKYILGRISALKK.E.MCDKYNKCEDSKEALAENN.L.HLPKLAEKDG.C.FQ......S..GF..N..Q....DTCLTRIATG..LLEFQVHLKYL..QANYEG..DKEN..ANSVYF.STKVLLQ...MLMEKVK....NQ..DEVT.TPDPTTDTGLQAILKSQ.DKWLKQTTIH.LILRNLEDFLQFSLRAVRVM.................................
B4DNV3_HUMAN/1-91                    .............................................................------------------------..-..------------------.-.------MCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKV-....--..----.-----------------.----------.--------------------gvssfpqlg........................
A0A1L8FW11_XENLA/1-130               ............................................................m------------------------..-..------------------.-.------------EMLAENN.L.QLPKITTKDR.C.FS......S..GF..Q..K....NKCLNKIHHD..LLIFEIYLLHV..KETFRS..ERST..LESIEY.KTNVLTG...AIKRMMK....RS..-KTE.SDDKETNTQITQVRKSE.NLWIQKVTNR.LILQAFIDCIQKTARAVRY-i................................
L9KY14_TUPCH/65-171                  .......................................................hinlmk------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..N..E....ETCLRRINNG..LQEFQVYLEFL..EKNLN-..DTDN..VRSVQI.YSRALMR...TLM----....SP..TTVT.SPSPDANASLLEKMQAQ.DKSMRTETAR.LILCRLDKFLQYAMRASRI-k................................
S7N395_MYOBR/33-214                  .............................................................PTPVPRGEDSKDDTTSNRPLLTSS..E..QIENLIKSILLEISDVKN.K.MCDNHESCKNSKEVLTENN.L.NLPKLARKDG.C.FH......S..GF..N..Q....ETCLIRITTG..LLEFQVYLQYL..QNTFEG..---H..AQAMKI.GTKALVN...ILRQKMK....NP..VEET.IPDPTTNTGLLEKMHAQ.KNWLKTTTIH.LILRSLEDFLQFTQRAIRM-.................................
S9YC60_CAMFR/27-70                   .............................................................PTPVPLGEDFKDGTTSNRP-FTSP..D..KSEELIKYILGRISAMRK.E.-------------------.-.----------.-.--......-..--..-..-....----------..-----------..------..----..------.-------...-------....--..----.-----------------.----------.--------------------e................................
IL6_MOUSE/26-211                     .............................................................PTSQVRRGDFTEDTTPNRPVYTTS..-..QVGGLITHVLWEIVEMRK.E.LCNGNSDCMNNDDALAENN.L.KLPEIQRNDG.C.YQ......T..GY..N..Q....EICLLKISSG..LLEYHSYLEYM..KNNLKD..NKKD.kARVLQR.DTETLIH...IFNQEVK....DL..HKIV.LPTPISNALLTDKLESQ.KEWLRTKTIQ.FILKSLEEFLKVTLRSTRQ-t................................
#=GR IL6_MOUSE/26-211          SS    .............................................................XX--------------SS---SHH..-..HHHHHHHHHHHHHHHHHH.H.TTTT-HHHHTTSTTTGGG-.-.SS----S-S-.S.-S......S..S-..-..S....-S-S---HHH..HHHHHHHHHHH..HHT--H..HHHH.HHHHHHH.HHHHHHH...HHHHHHH....HH..S---.-----HHHHHHH--S-S.S-SSHHHHHH.HHHHHHHHHHHHHHHHHHT--................................
A0A0A0A471_CHAVO/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.D.FL......T..FL..S.fQ....DKCLKKISSG..LYTFQTYLKYV..QETFTS..EKQN..VELLCY.STEHLAR...TIRQMVI....KP..DEVI.IPDSATQESLRAKLKSN.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
G1PT99_MYOLU/27-208                  .............................................................PTPVPRGEDSKDDTTSNRPLLTSS..E..QIENLIKSILLEISDVKN.K.MCDNHESCKNSKEVLTENN.L.NLPKLARKDG.C.FH......S..GF..N..Q....ETCLIRITTG..LLEFQVYLEYI..QNTFEG..---H..AQAMKI.GTKALVN...ILRQKMK....NP..VEET.IPDPTTNTGLLEKMHAQ.KNWLKTTTIH.LILRSLEDFLQFTQRAIRM-.................................
F7CIZ3_MONDO/10-195                  ...................................ptpgswgkgftgyelssklpssipdl------------------------..D..SIVNHAKYLEKTASDLKE.E.ICRIHNLCDNSNEALAENN.L.LLPNITERDG.C.LP......S..SF..N..E....ETCLIKIISG..LQDFDIFLNYM..ETEMED..NR--..FQTLKL.STTQLAN...TLKTVIK....KT..DLVP.TTNPTTSSILLSELQSL.TAWSRKVGFR.LILWHYTRFIQGTVRAVRY-l................................
A9JPH4_HHV8/19-192                   ..................................................csgqpesqafd-----------------------K..E..RNQQRIDWLLSVVAACYE.D.LCANTGICQGKLEPMAFFN.A.DMPVVEQGSG.C.FP......P..SL..N..E....TRCLKDLAIG..VWGLVEPFVFL..NEHFGE..YVEH..VGAMHM.LARAIAW...DMRDHAN...rDL..YE-P.FELPVPKPKMLPLLRRL.TTWNKHIAAF.NILRRIERFANDANRALS--ym...............................
F7HV62_CALJA/27-212                  .............................................................PAPVPLGEDSKEVAAPNRQLLTST..E..RIDKHIRYILDGISALRK.E.ICNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLLKITTG..LLEFEVYLEYL..QNRFES..SKEQ..AGAVQM.STKGLIQ...SLQKKAK....NL..SAIA.TPDPATNASLLTKLQAQ.DQWLQGVTTH.LILRSFKDFLQNSLRALRQM.................................
A0A091PQH2_LEPDC/1-144               .............................................................------------------------..-..------------------.Q.MCKKFTICGNSMEMLVQNN.L.NLPQVTKEDG.D.FP......T..FL..S.fQ....DKCLRKISSG..LYTFQTYLQYV..QETFTS..EKQN..VEWLCY.STEHLAH...TVRQMVI....NP..SEVI.IPDSATQESLRTKLKSN.KTWVEKITTH.LILRDFTSFMEKTVRAIRY-v................................
I3LIW9_PIG/6-191                     .............................................................PTPGRLEEDAKGDATSDKMLFTSP..D..KTEELIKYILGKISAMRK.E.MCEKYEKCENSKEVLAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..Q....ETCLMRITTG..LVEFQIYLDYL..QKEYES..NKGN..VEAVQI.STKALIQ...TLRQKGK....NP..DKAT.TPNPTTNAGLLDKLQSQ.NEWMKNTKII.LILRSLEDFLQFSLRAIRIM.................................
IL6_BOVIN/27-208                     .............................................................PTPGPLGEDFKNDTTPGRLLLTTP..E..KTEALIKRMVDKISAMRK.E.ICEKNDECESSKETLAENK.L.NLPKMEEKDG.C.FQ......S..GF..N..Q....AICLIRTTAG..LLEYQIYLDYL..QNEYEG..NQEN..VRDLRK.NIRTLIQ...ILKQKIA....DL..--IT.T--PATNTDLLEKMQSS.NEWVKNAKII.LILRNLENFLQFSLRAIRM-k................................
A0A2K5KAT3_COLAP/27-164              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKV-....--..----.-----------------.----------.--------------------gvssfp...........................
A0A091PFU6_HALAL/1-143               .............................................................------------------------..-..------------------.Q.MCEKFTVCKNSMEMLAQNN.L.NLPKVTEEDG.C.LL......T..GF..D..E....DKCLRKISSG..LFTFQTYLEYI..QETFTS..EKQN..VESLCY.TTEHLAN...TIRQMVV....NP..DEVI.IPDSATQESLRAKLKSN.KNWIEKITTH.LILRDFTSFMEKTVRAIRY-l................................
G3USN5_MELGA/1-118                   ............................................................v------------------------..-..------------------.-.-------------------.-.-----TEEDG.C.LL......A..GF..D..E....EKCLRKLSSG..LFAFQTYLEFI..QETFAS..EKQN..VESLCY.GTKHLAA...TIRQMVI....NP..DEVV.IPDSATQKSLLAKLKSD.KAWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A087R7D0_APTFO/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.D.FL......T..FL..S.fQ....DKCLRKLSSG..LYTFRTYLQYV..QETFTS..EKQN..VESLCY.STEHLAR...TIRQMVI....NP..DEVI.IPDSATQESLRAKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A0D9RN63_CHLSB/27-212              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDVTTH.LILRSFKEFLQSSLRALRQM.................................
A0A091D1V2_FUKDA/26-210              .............................................................PTSQVL-KDFTDDTTRSKPT-TSA..S..QAFRLFTLVLYDVQELKS.E.LCKHNANCVEEER-ATLNN.L.NLPTIEIEDG.C.FY......N..GY..N..W....ETCHLKIITG..LLKFQIYLQYM..QNKLQS..DSENekAEKVYS.GVKSLSL...FMKAKVS....ST..EQTV.FPSPTENATLLKELESQ.NETQKFLIVH.IVLCSLEEFLQNSLRPIRK-a................................
A0A226P4Q5_COLVI/50-139              ..............................psaadssgeagldeeaearrglpecealawl------------------------..-..--------LHARAARLQD.E.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.C.LL......A..GF..D..E....A---------..-----------..------..----..------.-------...-------....--..----.-----------------.----------.--------------------rnrsapssg........................
A0A0G2JGF4_MOUSE/26-162              .............................................................PTSQVRRGDFTEDTTPNRPVYTTS..-..QVGGLITHVLWEIVEMRK.E.LCNGNSDCMNNDDALAENN.L.KLPEIQRNDG.C.YQ......T..GY..N..Q....EICLLKISSG..LLEYHSYLEYM..KNNLKD..NKKD.kARVLQR.DTETLIH...IFNQEIS....--..----.-----------------.----------.--------------------wshr.............................
A0A093IED3_EURHL/1-144               .............................................................------------------------..-..------------------.Q.MCDKFTVCENSMEVLVRNN.L.NLPKVTEEDG.LtFT......F..LS..F..Q....DKCLRKISSG..LYTFQTYLEYI..QETFTS..EKQN..IESLCY.STEHLAR...TIRQMVI....NP..NEVV.IPDSATQKSLRAKLRSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A2I4B000_9TELE/104-213             .......................................................fnvlsv------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..D..Q....EACLQMLAKG..LLTYMVLLKHV..DKEYP-..NNSI..VTGVRD.SVPKLIQ...MIKSKMR....SS..QQVK.AMTSSEEQQLLKELDNP.DAFTRKMRAH.SILCYLNFFLIDGER-----sfyr.............................
H3AI47_LATCH/2-148                   ........................................................ailvh------------------------..-..-----------------F.Q.LCDKYAVCDNSMETFTPNS.M.NLPKMD--DR.C.LQ......S..SF..N..K....EKCFTKIASG..LYAYHIHLLFV..QDIYTN..EGKV..VKDLRI.STEQLVD...AVKLMVK....DY..YEVP.ELDADAQKVLLAKLYSE.SDWLQKVTAR.LILRDFTHFMAKTARAIRR-i................................
G3UHF3_LOXAF/20-205                  .............................................................PNPKPLEGDSKDDAASNRPSLTSP..D..KTEELIRFILAEISVLRK.K.MCDKYDKCENSREALAGNN.L.KLPQMTEEDG.C.FH......S..GF..N..K....ETCLMKIITG..LSEFQIYLDYL..QNKFEG..SKAN..VIVVQN.STKALVQ...ILKQKIK....NP..EDVT.TPDPTANASLLSKLQLQ.TEWLKNTTIN.LILRSLDDFMQFSLRAVRIM.................................
I3J0Y3_ORENI/34-208                  gdfsgeeteeaemstvkpfniwrslfdsaqeyekafehhfqtlenrdqaldshtpasipkh------------------------..-..------------------.-.-------------------.-.----------.C.NI......T..KF..R..K....DACLQTLAKG..LLIYSVLLKHV..EKEYRS..-SLN..FSDAPS.NIGTLIDlagMVKGKMK....NR..NQVT.PLTSSEEEQLLKEVNSP.DPYHRKLHAY.SILRALKAFLSEGKRAVCR-m................................
A0A2I3LHM9_PAPAN/29-214              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKQIRYILDGISVLRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A2I3SUM2_PANTR/49-234              .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A1V4KBZ6_PATFA/1-142               .............................................................------------------------..-..------------------.-.MCEKFTVCGNSMEMLVQNH.L.NLPKVTEEDG.C.LF......A..GF..D..E....DKCLRKISSG..LYTFQTYLEYV..KETFIS..EKQS..VDLLCY.STEHLAR...TIRQMVI....NP..DEVI.IPDPATQESLRAKLKSN.KNWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
U3K550_FICAL/1-157                   ......................................................laqllhd------------------------..-..-----------RAKHLRD.E.MCEKFTVCQNSVEVLLRNN.L.NLPKVTEEDG.C.LL......A..GF..N..E....DKCLRKISSG..LYTFQTYLKYI..QETFTS..ENQN..VESLSY.STAHLAR...TIRRMVI....NP..EEVI.IPDAATQESLHTKLKTT.KDWTEKITIH.LILRDFTSFMEKTVRAVRY-l................................
A0A1U7QW01_MESAU/26-212              .............................................................PTSQVRRGDFTEDTTPNRPVYTTS..Q..QVGGLVTYVLREIYELRK.E.LCNNNPGCMDNDYVLLENN.L.ELPVIQINDG.C.LQ......T..GY..N..W....EICLLKITSG..LLDYQIYLEFV..TNNVQD..NKKD.kARVIQS.TIKTLSQ...IFKQEVK....GP..DKIV.TPSPTSKAILMEKLESQ.KEWPRTKTIK.LILKALEEFLEVTMRSTRQ-n................................
F6YS54_ORNAN/23-154                  .............................................................PTSKSSKEELSDVALPNKSPSSKQpfG..NPESLTKTLWKQANGLKD.K.ICDDYSLCEENKVVLAENN.M.NLPKMTEEDG.C.FL......S..GF..N..E....ETCLKRIVTG..LSEFQIYLKYV..QKTFKG..EEKI..LESIQN.YTKHLSN...ILKQ---....--..----.-----------------.----------.--------------------.................................
G3NRW1_GASAC/65-205                  .................................lhkkefedefenvvkynflenykvfsvp------------------------..-..------------------.-.-------------------.-.--------ER.C.PH......S..NF..S..K....EACLHRMAHG..LLVYTVLLKHV..EKEYPG..SL--..ICSLAKyYSGLLIN...LCKEKMR....NP..DQVA.ALTDRQEAQLLRGLNLP.SAFQRKMAAH.SVLRQLHYFLLDGRRAI---akr..............................
A0A1A6GRC6_NEOLE/113-298             .............................................................PTSRVXRGDFTEDTTPNRPVYTTS..Q..QVGGLITYILREILEMRK.E.LCNSNPDCIANDDALSENN.L.ELPVIQRNDG.C.FQ......T..GY..N..R....ESCLLKITSG..LLDYEIYLEFV..KNNVQD..NKKD.kARVIQS.TTKTLNQ...IFKQEVK....DP..GKLV.TPXPTSKAHLMEKLESQ.KEWSRTKTIQ.LILKALEEFLKTAS------envdn............................
A0A218VED9_9PASE/1-43                .............................................................------------------------..-..------------------.-.MCEKLTVCQNSMEMLLHNN.L.NLPKVTEEDG.C.LL......A..GF..N..E....A---------..-----------..------..----..------.-------...-------....--..----.-----------------.----------.--------------------rnss.............................
A0A2K5KAQ8_COLAP/29-214              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
IL6_MUSPF/27-210                     .............................................................PTPGPLGGDSKDDATSNRPPLTSA..D..KMEDFIRFILGKISALKK.E.MCEKYNKCEDSKEALAENN.L.NLPKLAEEDK.C.FQ......S..QF..N..Q....ETCLTRITTG..LQEFQIHLKYL..EANYEG..NKNN..AHSVYI.STKHLLQ...KLRP--M....NR..VEVT.TPDPTTDSSLQALFKSQ.DKWLKHVTIH.LILRSLEDFLQFSLRAIRIM.................................
VIL6_HHV8P/27-193                    ..................................................apefekdlliq------------------------..-..----RLNWMLWVIDECFR.D.LCYRTGICKGILEPAAIFH.L.KLPAINDTDH.C.GL......I..GF..N..E....TSCLKKLADG..FFEFEVLFKFL..TTEFGK..SVIN..VDVMEL.LTKTLGW...DIQEELN....KL..TKTH.YSPPKFDRGLLGRLQGL.KYWVRHFASF.YVLSAMEKFAGQAVRV----lns..............................
G1TX17_RABIT/1-144                   ...........................................................sg------------------------..-..---------------IHS.Q.MCDYNAKCLNRTAALAAPD.L.NLPKLTEKDK.C.SP......T..AL..N..K....EANLMKLGEGetLSEFQKHLELL..QNKSR-..----..ANDVQI.NSQALTQ...ILKQMCL....NP..DALI.TQPPKSDSW---RVHSQgAQWLKNMMIPpLSFAMLKKLLELHVRAVHLM.................................
A0A2K5KAS8_COLAP/27-212              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
IL6_MACMU/27-212                     .............................................................PAPVLPGEDSKNVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSNLRALRQM.................................
I3M4W8_ICTTR/20-207                  .............................................................PASEFKREKGENSVIRNKPTRASS..G..KTAGQISYLIKEVFEMRK.E.LCKNDETCIKSHVAVSENH.L.NLPKMTEKDG.C.FQ......T..GY..N..R....DNYLVQITSG..LLEFQVYLRYI..RNKFQE..GKNKdrAEHVQF.SSKALIE...ILKQEVK....DP..NKIV.FPSPTANIHLLAKLESQ.NDWQKVMTMQ.LILSNFENFLQFTLRAVRK-a................................
A0A151MQI6_ALLMI/62-170              ...........................................................kh------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..E....EKCLIKISSG..LFAFQPYLEYIhvQETFIS..EKQK..IETIWY.GTKHLAN...TVRQMME....NP..DAVP.IPDQTSQKTLLEKLKAN.KNWREKIATH.FILRDFTSFMEKTVRALRY-i................................
A0A1S2ZSU1_ERIEU/24-210              .........................................talpihettsasshgdatls-----------------TTAF--S..S..KTEGSIRYILGKISELKQ.E.ICENHSMCRNGMVALEDNN.L.NFPQITEDGG.C.LP......S..GF..N..K....DTCLNTITTS..LSEYQPYLNYL..QENYNL..NERT..AIDIQT.YFKVLIR...ILKQMEN....NA..DEIT.TPNPVKYDTLSKMLRSQ.NNWQMNTTFY.LTLQSLERFLQYTVRAIRMM.................................
A0A2K5KAS1_COLAP/26-211              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
K7FSQ0_PELSI/26-203                  ....................................nelssgmnslarspllpdceslawl------------------------..-..--------LHSKAAKLKD.E.MCEKFTVCDNSMEMLAQND.L.NLPKITEEDG.C.LL......S..GF..N..E....EKCLSGISSG..LFTFQTYLEYV..QETLIT..EKQK..VESICY.GTKHLAN...TVRQMVK....NP..GAVI.MPDPATQNTLFAKLKSN.KKWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
I3N2D4_ICTTR/20-207                  .............................................................PASELKREDGENSVTRNKPTRASS..G..KTAGQISYLIKEVFEMRK.E.LCKNDETCIKSHVAVSENN.L.NLPKMTEKDG.C.FQ......T..AY..N..R....DNCLVRITSG..LLEFQVYLRYI..RNKFQEgnNRDR..AEHVKF.SSKALIE...ILKQEVK....EP..NKIV.FPSPTANINLLAKLESQ.NDWQKVLTMQ.LILSNFEDFLKFTLRAVRK-a................................
F1PXV9_CANLF/22-207                  .............................................................PTPGPLAGDSKDDATSNSLPLTSA..N..KVEELIKYILGKISALRK.E.MCDKFNKCEDSKEALAENN.L.HLPKLEGKDG.C.FQ......S..GF..N..Q....ETCLTRITTG..LVEFQLHLNIL..QNNYEG..DKEN..VKSVHM.STKILVQ...MLKSKVK....NQ..DEVT.TPDPTTDASLQAILQSQ.DEWLKHTTIH.LILQSLEDFLQFSLRAVRIM.................................
A0A2D0Q0A7_ICTPU/47-192              ................................hkwlsiarqmrkdiasvgeqlkrdfpese------------------------..-..------------------.-.--------------FHKAK.I.DTPLLSSTDG.C.LP......S..DF..S..P....QKCLQRIYHG..LRVYQAYLPYI..ESENL-..MSAR..MMDVKV.GTTRLLH...LIKETVK....VY..EEVR.-PTS---------LPDA.SVWTRRRNIY.FILSNFADFMTDTCRAINYM.................................
A0A0Q3P9W6_AMAAE/45-227              ..................................................paadssgeael-----------EEAAGRQAALPD-..-..-CERLARLLHARAAQLQE.E.MCEKFTVCENSMEMLIQNN.L.NLPKVMEEDG.C.LL......T..GF..N..E....DKCLRKISSG..LYTFQTYLQFI..QETFTS..EKQN..IESLCY.TTEHLAH...TVKQMVI....NP..DEII.IPDSATQESLRAKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A091MIH5_9PASS/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLLQNN.L.NLPKVTEEDG.D.FL......T..FL..S.fQ....DKCLKKISSG..LYMFQTYLKYV..QETFTS..EKQN..VESLSY.TTEHLAR...TIRQMVI....NP..DEVN.IPDAATQESLRAKLKSS.KAWLEKITTQ.LILRDFTSFLEKTVRAMRY-l................................
A0A091J5E4_EGRGA/1-105               .............................................................------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....DKCLRKISSG..LYTFQTYLEYV..QETFTS..EKQS..IKSLCY.STEHLAR...TIRQMVI....NP..NEVI.IPDSATQESLRAKLKSD.KTWIEKITIH.LILRDFTSFMEKTVRAVRY-l................................
M3X721_FELCA/44-225                  .............................................................PTPGPLGGD----ATSNRLPLTSA..D..KMEELIKYILGKISALKK.E.MCDNYNKCEDSKEALAENN.L.NLPKLAEKDG.C.FQ......S..GF..N..Q....ETCLTRITTG..LQEFQIYLKFL..QDKYEG..DKEN..AKSVYT.STNVLLQ...MLKRKGK....NQ..DEVT.IPVPTVEVGLQAKLQSQ.EEWLRHTTIH.LTLRRLEDFLQFSLRAVRIM.................................
H0WPC6_OTOGA/27-211                  .............................................................PTSGPLEVLEKDATPAKPLSLSTP..E..QTEGLITHIIMEINDLNG.K.MCSKGIKCEGDSHVMENNK.L.HLPRLEDDDG.C.FE......T..GF..N..K....EECLTRITYG..LSGYEKYLAYI..EGKFEG..DINE..AVALDL.GTKHLID...VLKQKLS....NP..TQVT.A-NPTTDSEVIAELDSQ.EDWQQYTAIH.IILVNLKEYLHKTLRALRH-i................................
C9J5B0_HUMAN/27-152                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...-------....--..----.-----------------.----------.--------------------.................................
A0A093HHJ7_STRCA/1-147               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.C.LL......S..GF..D..EarahEKCLRKISSG..LFAFQTYLEYV..QETFTS..ERQK..VESLCY.STKHLAT...TLRQMVI....NP..DDVI.IPDSATQKSLLVKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
M7B314_CHEMY/99-206                  ..........................................................lkd------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..E....EKCLRGISSG..LFTFQTYLEYV..RETFIS..EKQK..VESIYY.GTKHLAN...TVRQMMK....NP..DAVI.MPDPATQSTLFAKLKSN.KKWIEKISTH.LILRDFTSFMEKTVRAVRY-l................................
I3N090_ICTTR/20-207                  .............................................................PASEFKREKGENSVIRNKPTRASS..G..KTAGQISYLIKEVFEMRK.E.LCKNDETCMKSHVAVSENH.L.NLPKMTEKDG.C.FQ......T..GY..N..R....DNCLVRITSG..LLEFQVYLRYI..LNKFQE..GKNKdrAEHVQF.ISKALIE...ILKQEVK....DP..NKIV.LPSPTANIHLLAKLASQ.NDWQKVMTMQ.LILSNFENFLQFTLRAVRK-a................................
A0A1D5R9U6_MACMU/40-225              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
H2TB95_TAKRU/87-208                  ..................................................drykipslpak------------------------..-..------------------.-.-------------------.-.----------.C.PY......S..NF..G..K....DACLRRLLEG..LLIYSVLLKRV..EEEFPS..-SSI..LSEVRF.YSNILIK...ELENKVR....DR..DQVM.RLTSSQEEQLLKDTDYP.DTFHRKMTAH.GILYNLHYFLVDCRRVI---nkr..............................
A0A091HXZ8_CALAN/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVRNN.L.NLPKVTEEDG.D.FL......T..FL..S.fQ....DKCLRKISSG..LYTFTTYLEYI..KETFTS..EKQN..IESLCY.STEHLAR...TVRQMVI....NP..EEVT.IPDSATQKSLRTKLKSN.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
IL6_SHEEP/27-208                     .............................................................PTPGPLGEDFKNDTTPSRLLLTTP..E..KTEALIKHIVDKISAIRK.E.ICEKNDECENSKETLAENK.L.KLPKMEEKDG.C.FQ......S..GF..N..Q....AICLIKTTAG..LLEYQIYLDFL..QNEFEG..NQET..VMELQS.SIRTLIQ...ILKEKIA....GL..--IT.T--PATHTDMLEKMQSS.NEWVKNAKVI.IILRSLENFLQFSLRAIRM-k................................
A0A2I3LGB1_PAPAN/27-212              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKQIRYILDGISVLRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A218VED9_9PASE/49-158              ........................................................pvylg------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....DKCLRKISSG..LYTFQTYLKYI..QETFIS..ENQN..VESLSY.STEHLAR...TIRQMVI....NP..EEVI.IPDAATQESLHTKLKST.KAWTEKITIH.LILRYFTSFMEKTVRAVRY-l................................
G7P0R5_MACFA/81-221                  .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKV-....--..----.-----------------.----------.--------------------gvssflhlg........................
A0A0G2JFG1_MOUSE/9-194               .............................................................PTSQVRRGDFTEDTTPNRPVYTTS..-..QVGGLITHVLWEIVEMRK.E.LCNGNSDCMNNDDALAENN.L.KLPEIQRNDG.C.YQ......T..GY..N..Q....EICLLKISSG..LLEYHSYLEYM..KNNLKD..NKKD.kARVLQR.DTETLIH...IFNQEVK....DL..HKIV.LPTPISNALLTDKLESQ.KEWLRTKTIQ.FILKSLEEFLKVTLRSTRQ-t................................
G3QRH2_GORGO/26-211                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DVIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
H2LFW7_ORYLA/93-204                  ...........................................................vk------------------------..-..------------------.-.-------------------.-.----------.C.PM......S..NY..S..K....EACLQRLAQG..LLVYTVLLKQV..EKEYPD..N-SI..LREIKP.GIPLLVA...QIKEKMK....RS..ERVP.APSSSQEEQLLKQLDSP.DTFQRRMTAH.SILSHLRFFLIDGKRAFR--k................................
H2QU89_PANTR/27-212                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A091R2R5_MERNU/1-145               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.SdFL......T..FF..S.fQ....DKCLKKISSG..LYTFQTYLEYV..QETFTS..EKQK..VESLCY.STEHLAH...TIRQMVI....NP..DEVI.IPDSATQESLRAKLKSN.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
G1U0P1_RABIT/29-208                  ............................................................h-TPLPLTEGFTNDATSNIPQSTAG..-..KAGEHMIHITKKIFELRE.K.MCDYNAKCLNRTAALAAPD.L.NLPKLTEKDK.C.SP......T..AL..N..K....EICLMRITIE..LLEFQIYLEYI..QNKFRN..DEENarAKDVQI.SLQVETE...LLMQKVK....KI..KVVP.TLSPSTKSGLLEKLQSK.NKWLN-----.--LRSLEVFLEHSLRAMHMM.................................
IL6_PIG/27-212                       .............................................................PTPERLEEDAKGDATSDKMLFTSP..D..KTEELIKYILGKISAMRK.E.MCEKYEKCENSKEVLAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..Q....ETCLMRITTG..LVEFQIYLDYL..QKEYES..NKGN..VEAVQI.STKALIQ...TLRQKGK....NP..DKAT.TPNPTTNAGLLDKLQSQ.NEWMKNTKII.LILRSLEDFLQFSLRAIRIM.................................
A0A2I3FSJ5_NOMLE/27-175              .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNRSNMCESSKEALVENN.L.NLPKMAAKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRLES..SEEQ..ARAVQM.STKVLIQ...FLQKKVS....--..----.-----------------.----------.--------------------vssfplgvgedrlkds.................
A0A091SF61_NESNO/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.D.LL......T..FL..S.fQ....DKCLMKISSG..LYAFQTYLQFV..QESFTS..EKQN..IESLCY.TTEHLAR...TIKQMVI....NP..DEVI.IPDSATQESLRAKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A093H7M5_DRYPU/1-151               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLLRND.L.NLPKVTEEDG.C.IVelyltlS..PF..SlfQ....DKCLRKISSG..LYTFQTYLEYI..KETFAS..EKQN..VESLCY.STEHLAH...TIRQMVT....NP..DEVM.IPDPATRESLRAKLRTS.KSWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
G3HVW6_CRIGR/68-174                  ............................................................k------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..E....EICLLKITSG..LLDYQIYLEFV..TNNVQD..NKKD.kARVIQS.TTKTLSQ...IFKQEVK....DP..DKIV.MPSPTSKAILIEKLESQ.KQWPRTKTIE.LILKALEEFLKVTMRSTRQ-n................................
A0A226P4Q5_COLVI/166-272             ...........................................................sp------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....EKCLRKLSSG..LFAFQTYLEFV..QETFAS..EKQK..VESLCY.STKHLAA...TIRQMVI....NP..DEVA.IPDSAARKSLLAKLKSD.KAWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
G3WCK1_SARHA/22-205                  ..................................................pstltpdalgv---------------SSKPALGTT..DlgKCKSLAKTLYKEADALKE.E.NGENQSMCDNSSTILAENN.L.VFPNLTEQDG.C.FY......S..GF..N..K....ETCLINLISK..LQEFDGYFQFM..ENELKE..KKSR..IEALKM.FTTQLAE...SLKKLMM....GA..DLVP.TLNPTASHDLVLKLKSL.NEWSRKVALH.LSLCRYIKFMEHTIRAIRNM.................................
H2PMP3_PONAB/27-212                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A1S3FSW2_DIPOR/26-213              .............................................................PTSEVPREEVTSNATSDGPTYAST..Q..NAEDQISYTLMKIKELKE.E.VCNNEEKCVRKDNALSEEK.L.NLPKMTVEDG.C.FE......S..GH..K..R....DTCLLKITSG..LLEFQIYLKYI..QNKFQS..SEKNnkAKDVKS.STKSVIQ...LLMQEIK....NQ..DEIV.FPSPTANALLLKELESQ.NEWQKNMIIH.LILSSLETFLQFSLRALRI-l................................
V8PIC6_OPHHA/41-171                  ...................................srtsaagrvqlniptelalwlqgtaa------------------------..-..------------------.-.-------------------.-.----------.-.--......-..TW..N..Q...eESCLRKLSSG..LYVFRTFLEYI..EETTQ-..---R..SVSIST.GAQHLAE...TLKSMMN....NP..ETVS.TPPPDTQKTLAAKLREQ.RAWNMIVTKH.FILQAFTLFMETTSRVIRL-l................................
A0A2K5NHW0_CERAT/29-214              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...LLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
H3CA23_TETNG/47-201                  ................dalavalesvlratkrhkkeflaefqgevkyefldrykipslpak------------------------..-..------------------.-.-------------------.-.----------.C.PY......S..NF..G..Q....DACLRRLLEG..LLVYSVLLKHV..EQEYPL..--SR..ISEVRY.YSNVLIK...EVENKVK....ER..GQVT.TLSSSQQEQLLRAVDRS.DTFHRRMTAH.GILYNLHYFLVDCRRV----ivnk.............................
A0A091GA98_9AVES/1-143               .............................................................------------------------..-..------------------.-.MCEKFTVCENSMEMLVRNN.L.NLPKVTEEDG.D.FL......T..LF..S.fQ....DKCLKKISSG..LYTFQTYLQYV..QETFVS..EKQN..IESLCY.STEHLAR...TIRQMVI....NP..DEVI.IPDSATQESLHAKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAIRY-l................................
IL6_HUMAN/27-212                     .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
#=GR IL6_HUMAN/27-212          SS    .............................................................XXXXXXXXXXXXXXXXXXXXHHHH..H..HHHHHHHHHHHHHHHHHH.H.HHHTCSTTSSTTTHHHHTT.S.SS---SGGGT.-.SS......T..T-..-..H....HHHHHHHHHH..HHHHHHHHHHH..HTSGST..THHH..HHHHHH.HHHHHHH...HHHHHTT....TS..TTT-.-SSHHHHHHHHHHHHTS.-HHHHHHHHH.HHHHHHHHHHHHHHHHHTT-.................................
B5MCZ3_HUMAN/5-189                   ..........................................................sti----PPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A096NGM9_PAPAN/26-211              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKQIRYILDGISVLRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
IL6_HORSE/27-208                     .............................................................PTPLPLGED---ETTSNGPLLTTA..D..KTKQHIKYILGKISALKN.E.MCNNFSKCENSKEVLAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..Q....ETCLMKITTG..LSEFQIYLEYL..QNEFKG..EKEN..IKTMQI.STKVLVQ...ILMQKMK....NP..-EVT.TPDPTAKSSLLAKLHSQ.NEWLKNTTTH.LILRSLEDFLQFSLRAVRIM.................................
A0A226MNA1_CALSU/50-139              ..............................psaadssgeagldeeaearrglpecealawl------------------------..-..--------LHARAARLQD.E.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.C.LL......A..GF..D..E....A---------..-----------..------..----..------.-------...-------....--..----.-----------------.----------.--------------------rnrsapssg........................
R4GCE6_ANOCA/25-210                  .............................pvgdssgedelgdepqtssqeyspqractglf------------------------..-..------WGLHSTASGWKK.E.LCKEQNACKGSMEMLVQNN.L.HLPKITPEDG.C.SY......T..GF..Q..K....ETCLRRLSSG..LYAYQAYLEYI..DDAFSK..TVQM..SGSLWP.RTRQLAD...ILKSMMN....NP..DIVT.MLPPVTQDMVSIKLREQ.KAWNITVIKF.LILQDFISFLEKTARAF---cr...............................
A0A2I2ZF86_GORGO/14-199              .........................................................kqdi----SQREDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DVIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A1D5QRZ4_MACMU/29-214              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A091VT22_OPIHO/1-105               .............................................................------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....DKCLKKISSG..LYAFQTYLEYV..RDTFTS..EKQN..VESLCY.ATEHLAR...TLRQMVI....NP..DEVV.IPDSATQESLRAKLRSD.KAWIEKITTH.LILRGFTSFMEKTVRAVRY-l................................
IL6_CERAT/27-212                     .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCDSTKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...LLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
IL6_TAKRU/82-203                     ..................................................drykipslpak------------------------..-..------------------.-.-------------------.-.----------.C.PY......S..NF..G..K....DACLRRLLEG..LLIYSVLLKRV..EEEFPS..-SSI..LSEVRF.YSNILIK...ELENKVR....DR..DQVM.RLTSSQEEQLLKDTDYP.DTFHRKMTAH.GILYNLHYFLVDCRRVI---nkr..............................
F7DMU2_CALJA/27-212                  .............................................................PAPVPLGEDSKEVAAPNRQLLTST..E..RIDKHIRYILDGISALRK.E.ICNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLLKITTG..LLEFEVYLEYL..QNRFES..SKEQ..AGAVQM.STKGLIQ...SLQKKAK....NL..SAIA.TPDPATNASLLTKLQAQ.DQWLQGVTTH.LILRSFKDFLQNSLRALRA-n................................
G3HVW6_CRIGR/26-70                   .............................................................PTSQVRRGDFTEDTTPNRPVYTTS..Q..QVGGLVTHVLREIFELRK.E.-------------------.-.----------.-.--......-..--..-..-....----------..-----------..------..----..------.-------...-------....--..----.-----------------.----------.--------------------e................................
A0A2K5NHL6_CERAT/27-212              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...LLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A2I2ZVU2_GORGO/27-212              .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DVIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
H9A0J9_DANRE/37-210                  ..........................................eisgdevqdvdvksllgdr------------------------..Q..KWHLMARDLYKDVKTLRD.E.QFERDFREMVNMTAFEGVR.I.STPLLKPSDR.C.LS......K..NF..S..T....ERCLTRIYSV..LTWYKDNWNYI..EKENL-..TSVL..VNDIKH.STKRLLE...AINSQLQ....VR..----.--DGEMDQTSSTSLSFK.SAWTRKTTVH.SILFNFSSVMIDACRAINY-m................................
G3TFE8_LOXAF/27-212                  .............................................................PNPKPLEGDSKDDAASNRPSLTSP..D..KTEELIRFILAEISVLRK.K.MCDKYDKCENSREALAGNN.L.KLPQMTEEDG.C.FH......S..GF..N..K....ETCLMKIITG..LSEFQIYLDYL..QNKFEG..SKAN..VIVVQN.STKALVQ...ILKQKIK....NP..EDVT.TPDPTANASLLSKLQLQ.TEWLKNTTIN.LILRSLDDFMQFSLRAVRIM.................................
A0A2I3RKA9_PANTR/26-211              .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
I3MVL6_ICTTR/13-191                  .......................................................lvvata---------FPNSVTRNKPTRASS..E..KTAGQISYLIKEVFEMRK.E.LCKNDETRIKSHVAVSENN.L.NLPKMTEKDG.C.FQ......T..GY..N..R....DNCLVRITSG..LLEFQVYLRYI..RNKFQE..SKNRdrAEHVQF.SSKDLIE...ILKQEVK....DP..SKIV.FPSPTANINLLAKLESQ.NDWQKVMTMQ.LNLSKFEDFLAV--------pk...............................
A0A091KK85_9GRUI/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCQNSMEMLVQNN.L.NLPKLTEADG.D.HL......T..LF..S.lQ....DKCLTKISSG..LYKFQTYLEYI..QETFTS..EKQN..VESLYY.GTGHLAH...TLRQMVI....NP..DEVI.IPDLATQESIRTKLRSS.KAWIEKITIH.LILRDYTSFMEKTVRAIRY-l................................
W5PR13_SHEEP/27-210                  .............................................................PTPGPLGEDFKNDTTPSRLLLTTP..E..KTEALIKHIVDKISAIRK.E.ICEKNDECENSKETLAENK.L.KLPKMEEKDG.C.FQ......S..GF..N..Q....AICLIKTTAG..LLEYQIYLDFL..QNEFEG..NQET..VMELQS.SIRTLIQ...ILKEKVK....IA..GLIT.T--PATHTDMLEKMQSS.NEWVKNAKVI.IILRSLENFLQFSLRAIRM-k................................
A0A094KV70_ANTCR/1-105               .............................................................------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....DKCLKKIASG..LYAFKTYLEYV..QETFIS..EKQN..VESLCY.GTEHLAR...TLKQMVI....NP..DEVT.IPDPATQESLRTKLKSH.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
B5MC21_HUMAN/1-136                   .............................................................------------------------..-..------------------.-.------MCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A1D5QM02_MACMU/27-212              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
IL6_CANLF/22-207                     .............................................................PTPGPLAGDSKDDATSNSLPLTSA..N..KVEELIKYILGKISALRK.E.MCDKFNKCEDSKEALAENN.L.HLPKLEGKDG.C.FQ......S..GF..N..Q....ETCLTRITTG..LVEFQLHLNIL..QNNYEG..DKEN..VKSVHM.STKILVQ...MLKSKVK....NQ..DEVT.TPDPTTDASLQAILQSQ.DECVKHTTIH.LILRSLEDFLQFSLRAVRIM.................................
G3RRX2_GORGO/49-234                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DVIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
IL6_RAT/26-211                       .............................................................PTSQVRRGDFTEDTTHNRPVYTTS..-..QVGGLITYVLREILEMRK.E.LCNGNSDCMNSDDALSENN.L.KLPEIQRNDG.C.FQ......T..GY..N..Q....EICLLKICSG..LLEFRFYLEFV..KNNLQD..NKKD.kARVIQS.NTETLVH...IFKQEIK....DS..YKIV.LPTPTSNALLMEKLESQ.KEWLRTKTIQ.LILKALEEFLKVTMRSTRQ-t................................
L5KPK4_PTEAL/20-202                  .............................................................PIPVPSGEDSKDDTNSNRPQLTSP..N..QTENLIKSIFLEISEVRN.K.MCGNDDSCKNSKEVLTENN.L.NLPKMAEKDG.C.FQ......S..GF..N..Q....ETCLMKITTG..LLEFQIYLDYL..QNKFE-..--EN..AKAMQM.RTKALVQ...VLKQKVK....NP..NEIT.TPDPTTNSSLLAKLQSQ.SEWLQTTTIH.LILRSLEDFLQFTQRAVRIM.................................
B5MC14_HUMAN/27-165                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKV-....--..----.-----------------.----------.--------------------gvssfpq..........................
A0A098GML6_SALSA/35-214              ............................................wtsgeelatdslygetg----------------------AP..P..KWEQIIKMLVHEVTTLRN.QqFVEEFQKPVEEISSFSQHQvL.STPPHLSKTL.C.--......S..TT..N..K....EACLQEIRRG..LRVYQLLLQHV..KAEYPQ..-STL..LPSVTH.QTTVLIG...LVKDQMK....AA..EVVE.DLSASERERVLGEVSTG.TEWERKTSVH.AILRELRNFLVDTKRALRRM.................................
H3BX13_TETNG/53-202                  .....................alesvlratkrhkkeflaefqgevkyefldrykipslpak------------------------..-..------------------.-.-------------------.-.----------.C.PY......S..NF..G..Q....DACLRRLLEG..LLVYSVLLKHV..EQEYPL..--SR..ISEVRY.YSNVLIK...EVENKVK....ER..GQVT.TLSSSQQEQLLRAVDRS.DTFHRRMTAH.GILYNLHYFLVDCRRV----ivnk.............................
A0A093IZX3_FULGA/1-147               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.S.VN......DllTFlsF..Q....DKCLRKISSG..LYTFQTYLEYI..QETFTS..EKQN..VESLCY.STEHLAR...TIRQMVI....NP..DEVI.IPDSATQESLRAKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
IL6_RABIT/28-214                     .............................................................PTSAPVREDSNTKASPD-KTLTPP..G..RTIESIRSILETIKELRK.E.MCDHDVNCMNRKEALAEVN.L.HLPRLIEEDG.C.FP......P..AV..N..N....ETCLLRITSG..LMEFRMYLEHL..QAKFRS..DEENtrVSMVLK.NIQHLIK...TLRPKVK....NL..NEEA.TLKPAVAVSLMENLQQK.NQWLKTTTIH.FILRGLTNFLEFTLRAVDLM.................................
A0A093PUX7_9PASS/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSVEMLLQNN.L.NLPRVTEEDG.D.FL......T..FL..S.fQ....DKCLKKISSG..LYTFQTYLKYV..QETFIS..ENQN..LESLCY.STEHLAH...TIRQMVI....NP..EEVI.IPDAATQESLRTKLKSS.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A1L8FR84_XENLA/40-211              ................................................eeidnapaensav------------------------..-..---ALAKLIEQEAASLQT.K.LCDNHGVCDNSMEMLAENN.L.QLPKITTEDM.C.FS......T..EF..Q..K....DKCLNKIHHD..LLIFEIYLLHV..KETFRS..ERNT..VESIEY.KTKILAG...AVKRMMK....SS..KTESdDKETQTDTQIPQVLKSE.NLWIQKLTNR.LILQAFIDYIQKTARAVRY-i................................
F6RKC1_XENTR/24-211                  ......................................................plgsgee------ANDEANDGAAERSVFAVL..N..PV-ALAKLIEREAASLQI.K.LCDNHGVCDNSLEMLAENN.L.QLPKISTEDR.C.FS......L..GF..Q..K....DKCLNKIHRD..LSIFKIYLVHV..KETFIS..EKNT..VESLQY.KTQILAG...AIKKMIQ....IMkrTETE.SDDKGTNIQVLQALKSE.NLWRQRVTNR.LILQAFIECIQKTARAVRY-y................................
A0A226MNA1_CALSU/163-272             ........................................................sllsp------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....EKCLRKLSSG..LFAFQTYLQFV..QETFAS..EKQK..VESLCY.STKHLAA...TIRQMVI....NP..DEVA.IPDSAAQKSLLAKLKSD.KAWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A2I3S6T5_PANTR/14-199              .........................................................kqdi----SQREDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNKSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A2K5NI63_CERAT/26-211              .............................................................PAPVLPGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...LLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
A0A087VBL6_BALRE/1-147               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLLQNN.L.NLPKLTEEDG.C.LL......A..GF..N..SlsflDKCLKKISSG..LYTFQPYLKYV..QETFTS..EKQN..VELLCR.STERLAH...NIRQMVI....NP..DEVI.IPDSATQESLRAKLKSD.KTWIEKITTH.LILRDYTSFMEKTVRAIRY-l................................
A0A2K5KAR6_COLAP/7-190               ..........................................................ipw-----SGEDSKDVAAPHSQPLTSS..E..RIDKHIRYILDGISALRK.E.TCNRSNMCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
U3K549_FICAL/23-132                  ........................................................tflsf------------------------..-..------------------.-.-------------------.-.----------.-.--......-..--..-..Q....DKCLRKISSG..LYTFQTYLKYI..QETFTS..ENQN..VESLSY.STAHLAR...TIRRMVI....NP..EEVI.IPDAATQESLHTKLKTT.KDWTEKITIH.LILRDFTSFMEKTVRAVRY-l................................
F7FS80_MACMU/1-136                   .............................................................------------------------..-..------------------.-.------MCESSKEALAENN.L.NLPKMAEKDG.C.FQ......S..GF..N..E....DTCLVKIITG..LLEFEVYLEYL..QNRFES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPEPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQSSLRALRQM.................................
G1S4D6_NOMLE/27-212                  .............................................................PAPVPPGEDSKDVAAPHRQPLTSS..E..RIDKQIRYILDGISALRK.E.TCNRSNMCESSKEALVENN.L.NLPKMAAKDG.C.FQ......S..GF..N..E....ETCLVKIITG..LLEFEVYLEYL..QNRLES..SEEQ..ARAVQM.STKVLIQ...FLQKKAK....NL..DAIT.TPDPTTNASLLTKLQAQ.NQWLQDMTTH.LILRSFKEFLQYSLRALRQM.................................
H0YWY1_TAEGU/1-144                   .............................................................------------------------..-..------------------.Q.MCEKFTVCQNSMEMLLHNN.L.NLPKVTEEDGfC.LL......K..RT..V..E....DKCLRKISSG..LYTFQTYLKYI..QETFIS..ENQN..VESLSY.STEHLAR...TIRQMVI....NP..EEVI.IPDAATQESLHTELKST.KDWTEKITIH.LILRYFTSFMERTVRAVRY-l................................
A0A091W904_NIPNI/1-144               .............................................................------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.D.FL......T..FL..S.lQ....DKCLRKISSG..LYTFQTYLEYV..QETFTS..EKQN..IESLCY.STEHLAR...TLRQMVI....NP..SEVI.IPDSATQESLRAKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
M1F5B2_ANAPL/1-146                   ..........................................................lsp------------------------..-..------------------.Q.MCEKFTVCENSMEMLVQNN.L.NLPKVTEEDG.C.LL......A..GF..D..E....EKCLKKLSSG..LFTFQTYLEYV..QETFTS..EKQK..VESLCY.STKHLAT...TIRQMVI....NP..DEVV.IPDSATQKSLLTKLKSD.KTWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
A0A2I0MQA2_COLLI/1-142               .............................................................------------------------..-..------------------.-.MCEKFTVCGNSMEMLVQNN.L.NLPKMTEEDG.C.LF......A..GF..D..E....DKCLRKISSG..LYTFQTYLEYV..KETFIS..EKQS..VDLLCY.STEHLAR...TIRQMVI....NP..DEVI.IPDPATQESLRAKLKSN.KNWIEKITTH.LILRDFTSFMEKTVRAVRY-l................................
#=GC SS_cons                         .............................................................XXXXXXXXXXXXXXXXSSXXHCHH..H..HHHHHHHHHHHHHHHHHH.H.CCCTCCCCCTTTTCCHHCT.S.SS---SCGCT.S.SS......T..T-..-..C....HCHCHHHHHH..HHHHHHHHHHH..HCTGSC..CHHH.HHHHHHH.HHHHHHH...HHHHHCC....CC..TTT-.-SSHHHHHHHHHHHCTS.SHCCHHHHHH.HHHHHHHHHHHHHHHHHCT-.................................
#=GC seq_cons                        ..................................................................................................lh.th..hpp.c.hCpc.shCcsShEhLspNN.L.NLPKhsEcDG.C.a.......o..GF..N..c....-pCLhKItoG..LhpFplYL-Yl..QppFpo..pcpp..sculph.ST+hLhp...hlcppsp....N...-tls.hP-ssoptsLhsKLpup.ppWlcchThH.LILRshppFhppolRAlR...................................
//
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