#=GF ID   Imm3
#=GF AC   PF14425.10
#=GF DE   Immunity protein Imm3
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF SE   Manual 
#=GF GA   25.00 25.00;
#=GF TC   25.30 25.30;
#=GF NC   24.20 24.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR025678;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted Immunity protein, with a mostly all-alpha fold,
#=GF CC   present  in bacterial polymorphic toxin systems as an immediate
#=GF CC   gene neighbor  of the toxin gene [1] .
#=GF SQ   42
#=GS A0A437K6P1_9BACI/1-117    AC A0A437K6P1.1
#=GS A0A3Q8SEA6_9BACL/3-121    AC A0A3Q8SEA6.1
#=GS A0A6L8PMW9_BACAN/1-117    AC A0A6L8PMW9.1
#=GS A0A1I1SY68_9CLOT/9-130    AC A0A1I1SY68.1
#=GS A0A235B826_9BACL/1-111    AC A0A235B826.1
#=GS A0A0A3IMC3_9BACI/1-117    AC A0A0A3IMC3.1
#=GS A0A0A3IGU3_9BACI/1-120    AC A0A0A3IGU3.1
#=GS A0A559IW98_9BACL/6-121    AC A0A559IW98.1
#=GS Q81B97_BACCR/1-117        AC Q81B97.1
#=GS A0A559J4T2_9BACL/1-122    AC A0A559J4T2.1
#=GS A0A7W1XQT0_9BACL/1-120    AC A0A7W1XQT0.1
#=GS A0A398AUK8_9BACI/1-117    AC A0A398AUK8.1
#=GS A0A2S0U7F2_9BACL/3-126    AC A0A2S0U7F2.1
#=GS A0A1X7E6J4_9BACI/1-117    AC A0A1X7E6J4.1
#=GS A0A0Q4QR83_9BACL/1-124    AC A0A0Q4QR83.1
#=GS A0A398BLI3_9BACI/1-117    AC A0A398BLI3.1
#=GS A0A559J4T2_9BACL/121-234  AC A0A559J4T2.1
#=GS C0Z7L7_BREBN/1-119        AC C0Z7L7.1
#=GS C0Z7P0_BREBN/5-123        AC C0Z7P0.1
#=GS A0A559J4T9_9BACL/1-115    AC A0A559J4T9.1
#=GS A0A3Q8SEA6_9BACL/120-231  AC A0A3Q8SEA6.1
#=GS A0A090Y6K2_PAEMA/3-98     AC A0A090Y6K2.1
#=GS A0A268E957_9BACI/1-117    AC A0A268E957.1
#=GS A0A268DYP4_9BACI/3-121    AC A0A268DYP4.1
#=GS A0A1X7JP09_9BACL/1-105    AC A0A1X7JP09.1
#=GS A0A090Y3V1_PAEMA/1-111    AC A0A090Y3V1.1
#=GS A0A268E971_9BACI/1-117    AC A0A268E971.1
#=GS A0A7X2H408_9BACL/121-234  AC A0A7X2H408.1
#=GS K2JZ65_9GAMM/1-110        AC K2JZ65.1
#=GS A0A398BNJ7_9BACI/1-117    AC A0A398BNJ7.1
#=GS C0Z7L7_BREBN/126-224      AC C0Z7L7.1
#=GS A0A841RJ87_9BACI/1-117    AC A0A841RJ87.1
#=GS A0A7W1XRJ1_9BACL/1-120    AC A0A7W1XRJ1.1
#=GS E3E5M5_PAEPS/125-228      AC E3E5M5.1
#=GS A0A7X2H408_9BACL/1-122    AC A0A7X2H408.1
#=GS A0A1I1STT4_9CLOT/1-117    AC A0A1I1STT4.1
#=GS E3E5M5_PAEPS/1-124        AC E3E5M5.1
#=GS A0A504JS65_9FLAO/1-116    AC A0A504JS65.1
#=GS A0A074LQX2_9BACL/1-116    AC A0A074LQX2.1
#=GS A0A268DYP4_9BACI/120-227  AC A0A268DYP4.1
#=GS A0A5D0CMY2_9BACL/3-117    AC A0A5D0CMY2.1
#=GS A0A5J6PMH5_9BACI/1-117    AC A0A5J6PMH5.1
A0A437K6P1_9BACI/1-117               .................MEdWTYNELFETIQEVYQEFLSQ.NRGHSHAIARL.ADDFNN---L.GK.IEDI..IVDVAIGEILITY.NKVFIGYVEGITKRLNMFKE..ADVT.....NE..LTDE..ELADLTMRLEKV..LDGLSKAEIDYNPY-s.................
A0A3Q8SEA6_9BACL/3-121               ...............pk--.LNYREILKSFDETFQEYKYR.NMSNLEALAKT.FEDFELIMNS.GD.LEKA..TILVRYSELVLKQ.PYVFHKSKDIIIKLLNEVDY..EILR.....HT..LSES..EYEELIKRKKDV..LYNLSKKQLTNN---ara...............
A0A6L8PMW9_BACAN/1-117               .................MKdWEYNELFEAIQETYKELLDE.DRGYKYAIAKL.SDEFDN---L.GK.IEDV..IVDTAIGEIAIGH.DKVFIGLIEGITRRLSKFNP..QEAG.....DE..LTLE..EIKDLSRRINKV..IEGLKNVEVDYNPSA..................
A0A1I1SY68_9CLOT/9-130               .............mdin--.-EINELIENINEAYNEFLEK.NRGERYAIARL.FEEFDTYNNG.DL.VEDI..IVNMTIGELIIKQ.DSVFKGNLECIKKSLQRYENakEELK.....KG..ITEQ..ELDKIVFRVTKV..LNMLDKMNVDTNPK-c.................
A0A235B826_9BACL/1-111               .................MErWSYEEITQYIRDDFSEFLMD.DLNVKQATSRV.QVEYQNIIEE.SS.VEKL..FIYIVLAKLGLEH.GTLRDDIKEEVLKMITEEKL..LKIK.....DD..LTPN..EYKNLMKDTHDL..LS-------------lins..............
A0A0A3IMC3_9BACI/1-117               .................MKdWEYNELFDVIQETYEEFLET.GRGYRYAIARL.ADEFDR---L.GK.IEDV..ITDTAIGEIAITH.EKVFIGCIEGITRRLSMFNP..QEAE.....GE..LTEE..EIKDLSRRITKV..IEGLKKVEVDYNPSA..................
A0A0A3IGU3_9BACI/1-120               .................MEdWKYNELLESVNEMYGNLLNE.KKGYKYAVART.FYEFETVCNE.GG.TENL..LVHIAMGEIILKH.SKVFVGAVDAIKKELGNINI..EYLE.....EE..LSTE..EIKDLLKRINNV..SNRINEIVLDYDPS-t.................
A0A559IW98_9BACL/6-121               .................MN.WEYTELFEAVNETYQEFILE.NMSSTKALSRT.LSEFETTMNL.GI.FEKS..IVIIAYGEILLSH.LEVFHKSKEYLLKELNVLSL..QELE.....DQ..LPLE..QFYDLNARKKLI..LDKIEQKPV------tti...............
Q81B97_BACCR/1-117                   .................MKdWEYNELFHAIREAYEELLDE.ERGYRYAIAKL.ADEFDN---L.GK.IEGV..IVDTAIGEIAVDY.HIVFVGRIEGITKRLSMFNP..QEAE.....GE..LTVE..EIKDLSIRINNV..IEGLKNVKSDYKSS-v.................
A0A559J4T2_9BACL/1-122               ...............ma--.TCYEEYSEYINETYSEFKEEeKMSSKEAIART.FNEYDMSMKK.SE.TDKA..VISVIIAEILVSH.VRILNTFKDYMMDTISVLDF..KLIE.....QEniLSRD..QYNELISRKDNV..LKQLDYKPLDYYPR-v.................
A0A7W1XQT0_9BACL/1-120               .................MEdWKYDELLKAVKETYEDCIAD.KLSYRHAVAKT.FYEFETVCNE.GK.TESL..LVHTALGEILLHH.EKVFIGNIEAITEELTNVNF..DKLQ.....HE..LTPE..EIEDLSKRINRV..LKGLECVQIDYSPIA..................
A0A398AUK8_9BACI/1-117               .................MKdWEYNELIEAIQETYGELLEE.DRGYRYALAKL.ADEFDN---L.GK.IEDV..IVDTAIGEIAIKH.DKVFIGRIEGITKRLSMFNP..LDAE.....GE..LTKD..EIYDLTNRINKV..IDGLRNVEVDYNSSA..................
A0A2S0U7F2_9BACL/3-126               .................MA.WQYQDLIDEFYGDVERYKND.FYSHDEAINKA.FNEFYSESIV.DE.MEKA..LIFIVYVELSLQN.PRIFSKTKDILINELESINL..EKIEgqikdGQ..LTQK..QFNELTSRKEKA..LQEIKLMPIDFCNQA..................
A0A1X7E6J4_9BACI/1-117               .................MEnWEYDELFHTIKEFYEEFLEE.NRGYRYAAARL.ANEFDN---L.GK.VEDV..IADTAIGEIVMTH.EKVFVGTVEGITKRLSSFPL..EEAI.....GE..LSLG..EVKDLSQRIERV..LKGLREVTVDYNPRA..................
A0A0Q4QR83_9BACL/1-124               .................MA.WQYQDLIDEFYWDIERYKKE.YYSHDEAINMT.FDEFYSESIV.DE.MEKA..LIFIVYVELSLQN.PRIFSKTKDILIYELESINL..EEIEsqikdGQ..LTQK..QFEELSSRKEKA..LQEIKLMPIDLCNQA..................
A0A398BLI3_9BACI/1-117               ................m-EhFTYNELFEVIQEDYQEYLNK.NRGCRYAIARA.FNENLD---L.GN.IEDF..IGYTAIGEILITH.DKVFNGYLEAITNKLNSFNP..KEAS.....GE..LTAV..EIEDLSKRIKEV..LEGINHVEVDYEPN-t.................
A0A559J4T2_9BACL/121-234             ..............rvc--.WYYEELTDELNKFFDQINTD.TINKEEIIDRV.LNRFERDCKN.TL.SEKI..IVYTTLAENLLKL.GNTKIEGLYRIKEELQLFHV..EDIR....dEQ..LIEE..ERRDLVVRIYNV..LEQFNNI--------s.................
C0Z7L7_BREBN/1-119                   .................MK.RNYEALLGAFYGKYFEFKNM.KMSNDEALART.SNDFEGVLKL.GE.MENA..VVHIAIGNIILSH.TRTYYKVKDQLIEVLNSIDL..EKLQ.....LE..TSLD..EYQDILERRDMV..LDEIDNIQIDYDPYA..................
C0Z7P0_BREBN/5-123                   ................l-E.WEYQELFDEINKDYLAYRAR.NMSLSECLART.WDVYENVENM.GE.MEKI..VVNVAFGELSLLP.AKIFVNLKKHTVEALNQLNM..FELQ.....QV..LTTE..QLTDLMRRRDHV..LQNIEHKPVDAHP--lv................
A0A559J4T9_9BACL/1-115               ................m-QeWDYNELTEYVEEVFCNSIND.GLNALQAGGRC.LNEFANVIEE.GE.TEKT..IFYISLAHLQIGK.GILSVRIYEQVDDIIKVFDI..NNFV.....DE..LGLN..YAKDLSLRIESL..KTKMQSVEV------i.................
A0A3Q8SEA6_9BACL/120-231             ..............ram--.WYYDEMIDEVNNYYNSITSK.DKTPDQIAKEV.LDRFKRDCRN.TK.SEKI..GVYTTLAERLLED.GLADTIELKHIENSLKEFNV..DEVG.....EQ..LSKN..EKQKLQLRIERV..LERM-----------adn...............
A0A090Y6K2_PAEMA/3-98                ...............qk--.LTYEEITDLFDETFQEYKDK.NLSNLEALAKT.YEDLELIMSK.GD.LEKA..TVLIRYCELVLKQ.PYVFYKSKDYLLQYLNEIDY..DSLE.....QE..LSSI..QYQD--------..---------------..................
A0A268E957_9BACI/1-117               .................MEdWEYDELFNLINEYYQDFLAL.NRGHKYAIART.AYEFQN---L.GY.TEDF..IVDTAIGEISQTQ.DKVFIGYIEGITKRLSEFKR..EKVT.....KE..LTNE..EIEDLSKRINRV..IEGLKTVEVDYNPL-a.................
A0A268DYP4_9BACI/3-121               ................l-K.WEYKELVESFIEDYYSYKQN.NMSNRESLART.YNEYETVINQ.GE.MEKA..VIEILYGEFLLKQ.SKVLITAKEKTKEELLSIDF..TKLR.....TE..LTDD..EVKELISRKDNI..LLKLDEKPLDFCSEA..................
A0A1X7JP09_9BACL/1-105               ..............mls--.-SYKELEQYIVEDFEEFLDE.GLTLSQVTEKL.LVEYHRGITN.SN.VEKL..VVYLTIALLCLDK.SYLREDVKNGLNNMISDISS..IPLK.....EE..LEAE..DIKKILQDIE--..---------------qyk...............
A0A090Y3V1_PAEMA/1-111               ................m--.WYYDEMTNEVNRYYSSISS-.DSETKDVIAKVvLDRFKRDCRN.TK.SEKI..VVYTTLAERLLND.SLTESIEYQNIKNTLKEFNV..DEVG.....EQ..LSND..EKQKLQLRIRRV..LNHLS----------ddt...............
A0A268E971_9BACI/1-117               .................MRhWEYKELIEAIQETYEELLEE.DRGYRYALAKL.ADEFDN---L.GK.IEDV..IVDLVIGEIALEQ.EKVFAGRVEGITKRLNMFNL..KDAE.....GY..LTVE..EMDDLVKRVNRV..IEGLGKVEVDYDSS-v.................
A0A7X2H408_9BACL/121-234             ..............rvc--.WYYEELTDEVNKFLDQINTG.IINKDEIIAKV.FKRFERDCKN.TL.SEKI..IVCTTLAENLLNL.GYTRIEGLQKIKQELQLFNV..EDIC....nEQ..LIEG..ERKNLVVRIDNV..LEQLNNI--------g.................
K2JZ65_9GAMM/1-110                   ...............md-K.WSYEELQEFIHEDIEEFMGD.GLDIRQASSRV.QVEYAKSIED.SE.LEKL..IIYMVLCEEGVKH.GFLRDDIKEQTQELLRRIDL..GYCD.....PQ..LSDE..ERLKL-------..---------------rddmnrtsslla......
A0A398BNJ7_9BACI/1-117               .................MKdWEYNELFDAIQETYEELLDE.DRGYRYAIAKL.ADEFDN---L.GK.IEDV..IVDTAIGEIAIGH.DQVFVGRIEGITKRLSMFNP..QEAE.....DE..LTLE..EIKDLSRRINKV..IEGLKNVAVDYNPSA..................
C0Z7L7_BREBN/126-224                 mekevksyfgniicede--.--------------------.----SELVEKI.IERFERDCDK.TL.SENI..VVKTTLAELLIRH.GIKSNEQIVKIRSELEQFDL..NNVG.....KQ..LSEF..EKLDLSIRIKEV..LDKL-----------..................
A0A841RJ87_9BACI/1-117               .................MKdWEYNELFEAIQETYEELLDE.DRGYKYAIAKL.SDEFDN---F.GK.IEDV..IVDTAIGEIAIGH.DKVFIGLIEGITRRLSKFKD..IDAS.....KE..LTKE..EIADLTNRIEKV..LVGLSKVEIDYNPSA..................
A0A7W1XRJ1_9BACL/1-120               ...............mv-D.WQYDELLNAVKETYEDFVDR.KLSYKLAFART.SYEYETVCNE.GK.TERL..LVYTALGEIALTH.EKVFIGVIDAIKKELTSVNF..NDLQ.....HE..LTPE..EIEDLSKRINRV..LKGLESVQIDYSPIA..................
E3E5M5_PAEPS/125-228                 ................r--.WFYNEIIDKV----NTYFVG.AESVEDTIDHV.MECFEREFRYkDC.AKKN..VYTTIVENLIRQS.ERVP----EYIIDEIKFGYF..DNSQ.....FE..LTEE..ESQDLSKRITKV..LEDLD----------ifh...............
A0A7X2H408_9BACL/1-122               ................m-A.TSYEEYLEYINETYNEFKEEgKMSNKEAIART.FNEYDMSMKK.SE.TDKA..VISVTIAEILISH.LRILNTFKDYMINTISKLNF..KLIEq...dNE..LSRE..QHIALFIRREQV..LKQLDNKPLDYYPR-v.................
A0A1I1STT4_9CLOT/1-117               .................MKeWEFDELYEYIEEVFNKSLND.GLNELQAGGRC.LYEFANVIED.GE.TEKQ..IVYTTIATLEIKY.GVLSQRIFEEVSRIIDTFRE..TNIR.....EE..LDLDlgEIDKFTNIINNL..RVNMDAVKI------q.................
E3E5M5_PAEPS/1-124                   .................MT.WIYQELIDSFIEECDEYKLQ.HQSPSEAISRA.FDENYSESYS.DD.MKKA..VLNVISAELKLKQ.PRIYKLAKENYIRDLKSIDF..EKVKkhiqsGQ..LNEK..EFEELYSRRNKV..LVDLEKMPVDLCPKA..................
A0A504JS65_9FLAO/1-116               .................MRyWKYQELVDSINESYLLGLDQ.NRSIQQSIAGV.SEDFWFYPED.ENiVTNL..ITLIQVLDLSIENmNGVYQGTIKVFENQLKLITD..ELLY.....KE..LDNT..EVD---------..---------------liklsildiqerikttni
A0A074LQX2_9BACL/1-116               ................m-EeWDYNELREYVCEVFTDSVDD.GLNSLQAGGRC.LYEFANVIEE.GE.TERS..VFYLSLLELQLKN.GMISSRVYDVAKNIIDNFAV..EQYA.....SE..LNSE..EILDLMELVNLL..KNNILKI--------eaci..............
A0A268DYP4_9BACI/120-227             ...............ea-R.WYYQEINENVKGFFEAESFE.SDNVGQVVNHV.LKRFERDCRN.TM.SENI..TIKVTLAELLIKK.GINVQEELNNILDELKQFNI..EDVG.....QQ..LSKE..EKEDLARRIKNL..L--------------nl................
A0A5D0CMY2_9BACL/3-117               ................e-K.ITYEKLMEYVPNDFDKFVSD.GLSSIQAVSRL.INEYEN--QT.DD.YEDVrwMFTVLLAEIGIKH.DCL---RDEIKLEALSIIND..KKLV.....DY..WKEE..GINDA-EVFNRVlhLEKVKN---------iiiefgs...........
A0A5J6PMH5_9BACI/1-117               .................MEdWEYNEIFEAINEDYNDYLKL.NRGHEYAIART.VNDYIN---L.GK.IEDF..IVDTAIGEILLSK.NKVFIGYVEGITKRLSMFED..LDAT.....SE..LTHE..EIADLTNRIEKV..LDGLTKVEIDYNPY-s.................
#=GC seq_cons                        ..................p.WpYpELh-tlpEsap-hhsc.shuhcpAlA+s.hsEF-s..p..uc.hEch..ll.ssluElhlpp.splhhthh-tlpcpLsphsh..pclp.....p-..Lop-..EhpDL.pRlppV..Lptlpph.l........................
//