#=GF ID   La_HTH_kDCL
#=GF AC   PF18177.2
#=GF DE   La HTH in kinetoplastid DICER domain
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Laks
#=GF GA   52.20 52.20;
#=GF TC   90.90 89.90;
#=GF NC   41.90 40.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   27536007
#=GF RT   RNA damage in biological conflicts and the diversity of
#=GF RT   responding RNA repair systems.
#=GF RA   Burroughs AM, Aravind L;
#=GF RL   Nucleic Acids Res. 2016;44:8525-8555.
#=GF DR   INTERPRO; IPR040545;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Winged HTH domain family observed in kinetoplastid DICER-like
#=GF CC   (DCL) enzymes, situated N-terminal to the KptA_kDCL domain
#=GF CC   Pfam:PF18176 [1].
#=GF SQ   4
#=GS Q57XV6_TRYB2/176-263  AC Q57XV6.1
#=GS A4HE49_LEIBR/192-291  AC A4HE49.2
#=GS A4HCQ0_LEIBR/333-422  AC A4HCQ0.1
#=GS Q57XF2_TRYB2/269-355  AC Q57XF2.1
Q57XV6_TRYB2/176-263             SLYEASLRYLRNVGMKTTASTN-----------.GWVSAEELYSYLKDRKHS.........LIVKVPDdivsecdvlPTTPARLLVVLSQLDLIGRLQFRWERSSKVDG
A4HE49_LEIBR/192-291             VLYEKTVSHLRTVSVAKSSMGTLSTPEHQHLASrGWLPIHQILSEISPDLEGepalkvlleWMRALDE.........SQRGTIYVALLTPLNVLGKLQLLHDGDWGEGG
A4HCQ0_LEIBR/333-422             LVMRRLKKMLRFGSPYYEHFVRKGVWAHILCSD.GWVPLQLIEEELAADTTT.........PVAKLPS.........KEKLKIVESLLCQHDNFQRFEVGYCLLRRSPF
Q57XF2_TRYB2/269-355             MWMHNLRFLLRLSDRYRDEFDD-NTLQSIKQSA.GWIPISEVQQLLEAQVTR.........--SNRQQ.........PPGRDWICELVKRHDLLGRFQVGTCDVEGSEF
#=GC seq_cons                    hlhcphhphLRhsuhhpsphss.ss.tp.h.us.GWlPlppl.p.Lpschps..........hsplsp.........spphshlhsLLsphDllGRhQltastsptssh
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