#=GF ID   Lectin_C_term
#=GF AC   PF18022.5
#=GF DE   Ricin-type beta-trefoil lectin C-terminal domain
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF04228
#=GF GA   27.10 27.10;
#=GF TC   27.20 27.30;
#=GF NC   23.70 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0066
#=GF RN   [1]
#=GF RM   21436237
#=GF RT   Structure and binding analysis of Polyporus squamosus lectin in
#=GF RT   complex with the  Neu5Ac{alpha}2-6Gal{beta}1-4GlcNAc human-type
#=GF RT   influenza receptor.
#=GF RA   Kadirvelraj R, Grant OC, Goldstein IJ, Winter HC, Tateno H,
#=GF RA   Fadda E, Woods RJ;
#=GF RL   Glycobiology. 2011;21:973-984.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the C-terminal domain of the beta chain found in
#=GF CC   Polyporus squamosus lectin protein (PSL). PSL binds specifically
#=GF CC   to glycans terminating with the sequence:
#=GF CC   Neu5Ac.alpha2-6Gal.beta. The C-terminal domain is not involved
#=GF CC   in the binding to the Neu5Ac.alpha2-6Gal.beta. The C-terminal
#=GF CC   domain is characterized by a central five-stranded beta-sheet
#=GF CC   that is flanked by three alpha-helices and topped by a short
#=GF CC   strand. It shows high fold similarity to its closest relative,
#=GF CC   the Gal.alpha1-3Gal-binding agglutinin from the mushroom
#=GF CC   Marasmius oreades agglutinin (MOA) [1].
#=GF SQ   6
#=GS A0A0C2WFZ8_9AGAM/318-415  AC A0A0C2WFZ8.1
#=GS F8QJ00_SERL3/185-288      AC F8QJ00.1
#=GS Q18HN0_HALWD/76-171       AC Q18HN0.1
#=GS A0A6M3VYW3_PFV2/59-148    AC A0A6M3VYW3.1
#=GS U1Q2S7_9EURY/76-171       AC U1Q2S7.1
#=GS F8Q9A8_SERL3/353-474      AC F8Q9A8.1
A0A0C2WFZ8_9AGAM/318-415             ................................YSVEKLCIICPQEVIDTVWRNQGLQNR---ESRPELYDSDYFAF..................Q...MKGAMCDWVQDNL..RA.P..-..VGL....LFGVMFG....ENNNGE.KHAYNWSLN.....QDL..TAV..TFFEPQNG-l..............
F8QJ00_SERL3/185-288                 ................................NTPDKIYWVVDHGLLKSIWYNANLGRGWQYHYVKDKFDFNDLAL..................A...FKSEMAKWRNDNV..RA.E..E..FGI....LCGVVFTa..pGQQGQN.ENAYNFVLG.....NNG..RGV..YFFEPETGR...............
Q18HN0_HALWD/76-171                  ................................IGPDTEYRIPTSYRTVKLYANL-FHQQLSQVYEHNRYDCDNFAF..................D...LRDSFT-------..RM.N..P..FIN....SVGVMID....---TEN.SHAYNVMLVddepkQGY..GNT..YMWEPQSAT...............
A0A6M3VYW3_PFV2/59-148               .............................qvl---DNRYWVTTVDDFREIVSRDWTKH---RRYIDDRFDCDNFAL..................H...FVARIN-------..-A.M..Y..GLN....SVGIVID....---YDA.AHAYNLAIV.....IDG..GNLrkVVIEPQTG-e..............
U1Q2S7_9EURY/76-171                  ................................IGPDTEYRVPKSYQSVKLYANL-FHRQLGQVYEHNRYDCDNFAF..................D...LRDAFT-------..RM.N..P..FIN....SIGVMID....---TER.SHAYNVIVVddqpkKRY..GSV..HMWEPQLA-k..............
F8Q9A8_SERL3/353-474                 ..............................yq--MNGIYWVLDKDLVKNIWAGANLGEGKKYTLRPELFDQDDFTLcalffhecirlsitnsssA...FKAQLAQWGSDNI..LA.N..G..LNL....LLGVMLGv..sTEEGSG.GQSCNFFLD.....SDF..STV..LFFDAQTG-n..............
#=GC seq_cons                        .................................ssDshYhVsspthhcplauNt.hpctht.pYcc-+aDsDsFAh..................s...h+uphs.........RA.s.....hh......lGVMls.......sps.uHAYNhhLs.....pch..usV..hhaEPQoG................
//