#=GF ID   Lectin_C_term
#=GF AC   PF18022.2
#=GF DE   Ricin-type beta-trefoil lectin C-terminal domain
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF04228
#=GF GA   27.10 27.10;
#=GF TC   27.40 27.50;
#=GF NC   24.00 26.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   21436237
#=GF RT   Structure and binding analysis of Polyporus squamosus lectin in
#=GF RT   complex with the  Neu5Ac{alpha}2-6Gal{beta}1-4GlcNAc human-type
#=GF RT   influenza receptor.
#=GF RA   Kadirvelraj R, Grant OC, Goldstein IJ, Winter HC, Tateno H,
#=GF RA   Fadda E, Woods RJ;
#=GF RL   Glycobiology. 2011;21:973-984.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the C-terminal domain of the beta chain found in
#=GF CC   Polyporus squamosus lectin protein (PSL). PSL binds specifically
#=GF CC   to glycans terminating with the sequence:
#=GF CC   Neu5Ac.alpha2-6Gal.beta. The C-terminal domain is not involved
#=GF CC   in the binding to the Neu5Ac.alpha2-6Gal.beta. The C-terminal
#=GF CC   domain is characterized by a central five-stranded beta-sheet
#=GF CC   that is flanked by three alpha-helices and topped by a short
#=GF CC   strand. It shows high fold similarity to its closest relative,
#=GF CC   the Gal.alpha1-3Gal-binding agglutinin from the mushroom
#=GF CC   Marasmius oreades agglutinin (MOA) [1].
#=GF SQ   5
#=GS F8QJ00_SERL3/185-288      AC F8QJ00.1
#=GS A0A0C2WFZ8_9AGAM/318-415  AC A0A0C2WFZ8.1
#=GS A0A140F3M5_9VIRU/59-148   AC A0A140F3M5.1
#=GS U1Q2S7_9EURY/76-171       AC U1Q2S7.1
#=GS Q18HN0_HALWD/76-171       AC Q18HN0.1
F8QJ00_SERL3/185-288                 ................................NTPDKIYWVVDHGLLKSIWYNANLGRGWQYHYVKDKFDFNDLAL..................AFKSEMAKWRNDNV..RAE..E..FGI....LCGVVFTa..pGQQGQN.ENAYNFVLG.....NNGRGV..YFFEPETGR...............
A0A0C2WFZ8_9AGAM/318-415             ................................YSVEKLCIICPQEVIDTVWRNQGLQNR---ESRPELYDSDYFAF..................QMKGAMCDWVQDNL..RAP..-..VGL....LFGVMFG....ENNNGE.KHAYNWSLN.....QDLTAV..TFFEPQNG-l..............
A0A140F3M5_9VIRU/59-148              ..............................qa--LDNRYWVTTVDDLREIVSRDWTKH---RRYIDDRFDCDNFAL..................HFVARIN-------..-AM..Y..GLN....SVGIVID....---YDA.AHAYNLAIV.....IDGGNLrkVVIEPQTG-e..............
U1Q2S7_9EURY/76-171                  ................................IGPDTEYRVPKSYQSVKLYANL-FHRQLGQVYEHNRYDCDNFAF..................DLRDAFT-------..RMN..P..FIN....SIGVMID....---TER.SHAYNVIVVddqpkKRYGSV..HMWEPQLA-k..............
Q18HN0_HALWD/76-171                  ................................IGPDTEYRIPTSYRTVKLYANL-FHQQLSQVYEHNRYDCDNFAF..................DLRDSFT-------..RMN..P..FIN....SVGVMID....---TEN.SHAYNVMLVddepkQGYGNT..YMWEPQSAT...............
#=GC seq_cons                        ................................huPDscYhVssstplcclauNt.h++phtpcYc+-RYDCDNFAF..................ch+uuhs.........RAs.....FlN....SlGVMID.......s-s.uHAYNlsLV.....pchGuV..ahaEPQoG................
//