GenomeNet

Database: Pfam
Entry: Lenti_VIF_2
LinkDB: Lenti_VIF_2
Original site: Lenti_VIF_2 
#=GF ID   Lenti_VIF_2
#=GF AC   PF07401.13
#=GF DE   Bovine Lentivirus VIF protein
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_21067 (release 10.0)
#=GF GA   22.00 22.00;
#=GF TC   24.70 24.30;
#=GF NC   20.30 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9440006
#=GF RT   Sequence data analysis reveals a relationship between LSR2, the
#=GF RT   recombinant fusion protein mimicing M.Leprae and VIF of bovine
#=GF RT   immunodeficiency virus (BIV). 
#=GF RA   Ramakrishnan S, Sukhaswami MB, Patil KM, Eswaran C; 
#=GF RL   J Biomol Struct Dyn 1997;15:605-609.
#=GF DR   INTERPRO; IPR009979;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Lentivirus viral infectivity
#=GF CC   factor (VIF) proteins. VIF is known to be essential for ability
#=GF CC   of cell-free virus preparation to infect cells [1]. Members of
#=GF CC   this family are specific to  Bovine immunodeficiency virus (BIV)
#=GF CC   and Jembrana disease virus which also infects cattle.
#=GF SQ   3
#=GS C9DI72_CAEV/62-209  AC C9DI72.1
#=GS C0JIH0_CAEV/65-219  AC C0JIH0.1
#=GS VIF_JEMBR/1-197     AC Q82852.1
C9DI72_CAEV/62-209             ........edrtyeywkigrepwvmklrrrkgelrrglav----------------------------------------------------------------------VW--QYQCQGNWEDVGKWFTDTGNYRHVD-NKFWFHWrVAMCSCHKGGFQVRDFLLGGHR-WDLCKSCIQGEIVRTTDANSLQRWSLLQLARNHPFVVMPLWRAR------------------------rvptqdfpwcrnptg.....
C0JIH0_CAEV/65-219             yehweinswewkmklrrvkqwidprgtgtpwqykvgkdwk-----------------------------------------------------------------------------------SIGVWFLQAGDYTKVDRHFWWAWR.IVICSCRKEKFDIREFLMGKHR-WDLCKSCAQGEVIRHTRPKSLERLAWLQLVDTHTFQVLPLWRARRGSTI-------------------dfpwcrdttgfvqawtiqdc
VIF_JEMBR/1-197                ........................................MERTIQSPMGRRRGSSGRRKRNANIISPPAYAIYPAPQYRYPRWEFVMNDLYSQTARLQKEEIIITYRYAVWAREWKIQTGFLDLGYLMTPAGTHTTGELNELDLFW.VRYTLCQHRSPKWRELLLGEMT-HTSCRRTAQAAVVSHTKPHTLQRLAGLTLVCNQNLCWYPVGTVTRNSPLWMHFTTGKEPTIQQLSGHP....................
#=GC seq_cons                  .........-hphchh+ltp...shthtp.ht.hhtt.hh......................................................................VW..paphQssa.DlGhWFTsAGsYT+VDhNcaWhaW.VshCSC+KcuFclREFLLGcHR.WDLCKSCAQGEVVRHT+P+SLQRLAhLQLVcNHsFsVhPLWRARRsSsl...................chPhpc.shshs.sh.....
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