GenomeNet

Database: Pfam
Entry: LmjF365940-deam
LinkDB: LmjF365940-deam
Original site: LmjF365940-deam 
#=GF ID   LmjF365940-deam
#=GF AC   PF14421.8
#=GF DE   A distinct subfamily of CDD/CDA-like deaminases
#=GF PI   CDD_CDA_1;
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF SE   Manual
#=GF GA   45.70 45.70;
#=GF TC   47.30 46.00;
#=GF NC   34.10 42.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0109
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR032723;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A distinct branch of the CDD/CDA-like deaminases prototyped by 
#=GF CC   Leishmania LmjF36.5940. Members of this family are widely
#=GF CC   distributed across several microbial eukaryotes such as
#=GF CC   kinetoplastids,  chlorophyte algae, stramenopiles and the
#=GF CC   alveolate Perkinsus. Domain  architectures suggest that these
#=GF CC   proteins might possess mRNA editing  or DNA mutagenizing
#=GF CC   activity [1].
#=GF SQ   94
#=GS A0A6A3NVG4_9STRA/393-678  AC A0A6A3NVG4.1
#=GS A0A0G4GFE1_VITBC/163-209  AC A0A0G4GFE1.1
#=GS D0N437_PHYIT/361-620      AC D0N437.1
#=GS K3X7R0_GLOUD/360-635      AC K3X7R0.1
#=GS S9TLD4_9TRYP/400-468      AC S9TLD4.1
#=GS A0A3M6VVK1_9STRA/352-645  AC A0A3M6VVK1.1
#=GS T0RET2_SAPDV/307-526      AC T0RET2.1
#=GS W2YLS7_PHYPR/372-640      AC W2YLS7.1
#=GS A0A1E7F7I9_9STRA/650-893  AC A0A1E7F7I9.1
#=GS W4FWW5_9STRA/333-560      AC W4FWW5.1
#=GS V5B3J9_TRYCR/369-492      AC V5B3J9.1
#=GS A0A2R5GYM4_9STRA/464-686  AC A0A2R5GYM4.1
#=GS A0A3R7G344_9STRA/354-598  AC A0A3R7G344.1
#=GS C1N795_MICPC/486-700      AC C1N795.1
#=GS W6L9Z6_9TRYP/266-396      AC W6L9Z6.1
#=GS A0A5A8DK55_CAFRO/420-820  AC A0A5A8DK55.1
#=GS A0A0G4GFE1_VITBC/70-165   AC A0A0G4GFE1.1
#=GS W7U454_9STRA/578-921      AC W7U454.1
#=GS V5B3J9_TRYCR/489-561      AC V5B3J9.1
#=GS A0A024TN09_9STRA/318-550  AC A0A024TN09.1
#=GS A0A0S4IPY9_BODSA/226-297  AC A0A0S4IPY9.1
#=GS A0A1V9ZMX0_9STRA/308-518  AC A0A1V9ZMX0.1
#=GS A0A329SQ63_9STRA/361-647  AC A0A329SQ63.1
#=GS Q4CXE8_TRYCC/489-561      AC Q4CXE8.1
#=GS X6LM34_RETFI/14-136       AC X6LM34.1
#=GS A0A1Q9E3H3_SYMMI/62-150   AC A0A1Q9E3H3.1
#=GS M4BQJ0_HYAAE/354-656      AC M4BQJ0.1
#=GS A4IE07_LEIIN/127-253      AC A4IE07.1
#=GS Q38A89_TRYB2/370-496      AC Q38A89.1
#=GS S9TLD4_9TRYP/274-402      AC S9TLD4.1
#=GS W6KP16_9TRYP/361-493      AC W6KP16.1
#=GS A0A024GRI2_9STRA/349-596  AC A0A024GRI2.1
#=GS A4IE07_LEIIN/250-318      AC A4IE07.1
#=GS Q4CXE8_TRYCC/369-492      AC Q4CXE8.1
#=GS B7GB54_PHATC/685-977      AC B7GB54.1
#=GS A0A023AZW5_GRENI/26-125   AC A0A023AZW5.1
#=GS Q4DNI7_TRYCC/489-561      AC Q4DNI7.1
#=GS A0A6A3Y6C9_9STRA/401-686  AC A0A6A3Y6C9.1
#=GS A0A0M0JEH7_9EUKA/250-364  AC A0A0M0JEH7.1
#=GS A0A6G0XQD2_9STRA/318-536  AC A0A6G0XQD2.1
#=GS A0A0G4ECT7_VITBC/249-344  AC A0A0G4ECT7.1
#=GS Q4DNI7_TRYCC/369-492      AC Q4DNI7.1
#=GS A0A0G4EQ48_VITBC/40-132   AC A0A0G4EQ48.1
#=GS A0A1Q9E3B0_SYMMI/124-214  AC A0A1Q9E3B0.1
#=GS A0A1V9Z9N5_9STRA/301-522  AC A0A1V9Z9N5.1
#=GS A0A1X0NLM5_9TRYP/499-570  AC A0A1X0NLM5.1
#=GS Q38A89_TRYB2/493-566      AC Q38A89.1
#=GS A0A662WMZ3_9STRA/17-327   AC A0A662WMZ3.1
#=GS H3GUA2_PHYRM/361-650      AC H3GUA2.1
#=GS W2PRR7_PHYPN/372-640      AC W2PRR7.1
#=GS A0A2P4YKF2_9STRA/355-651  AC A0A2P4YKF2.1
#=GS A0A0M9G3M3_9TRYP/416-541  AC A0A0M9G3M3.1
#=GS A0A0N7L3D3_PLAHL/339-619  AC A0A0N7L3D3.1
#=GS K2NCU0_TRYCR/488-560      AC K2NCU0.1
#=GS C5KHT8_PERM5/69-173       AC C5KHT8.1
#=GS X6NWX0_RETFI/13-193       AC X6NWX0.1
#=GS C1EFE8_MICCC/391-596      AC C1EFE8.1
#=GS D7G3E7_ECTSI/557-885      AC D7G3E7.1
#=GS A0A485L9A1_9STRA/319-551  AC A0A485L9A1.1
#=GS A4HQB2_LEIBR/418-544      AC A4HQB2.1
#=GS A0A1X0NLM5_9TRYP/378-501  AC A0A1X0NLM5.1
#=GS Q4Q0G6_LEIMA/412-537      AC Q4Q0G6.1
#=GS A0A3R7NP46_TRYRA/368-489  AC A0A3R7NP46.1
#=GS A4HQB2_LEIBR/540-610      AC A4HQB2.1
#=GS A0A0M0JEH7_9EUKA/354-416  AC A0A0M0JEH7.1
#=GS K2NCU0_TRYCR/368-491      AC K2NCU0.1
#=GS A0A448YX44_9STRA/589-863  AC A0A448YX44.1
#=GS A0A225VY69_9STRA/350-624  AC A0A225VY69.1
#=GS A0A067CZ46_SAPPC/307-527  AC A0A067CZ46.1
#=GS K0SZS5_THAOC/573-878      AC K0SZS5.1
#=GS A0A0L0FHB9_9EUKA/30-302   AC A0A0L0FHB9.1
#=GS A0A3R7NP46_TRYRA/485-558  AC A0A3R7NP46.1
#=GS A0A422Q7Q1_9TRYP/489-561  AC A0A422Q7Q1.1
#=GS C5KBD0_PERM5/68-174       AC C5KBD0.1
#=GS W6KP16_9TRYP/489-557      AC W6KP16.1
#=GS G5AGH2_PHYSP/357-655      AC G5AGH2.1
#=GS V9EIB2_PHYPR/372-640      AC V9EIB2.1
#=GS A0A0S4IPY9_BODSA/82-230   AC A0A0S4IPY9.1
#=GS A0A6H5K1D9_9PHAE/552-610  AC A0A6H5K1D9.1
#=GS W6L9Z6_9TRYP/393-461      AC W6L9Z6.1
#=GS A0A5D6Y6H5_9STRA/303-621  AC A0A5D6Y6H5.1
#=GS A0A0G4ECT7_VITBC/341-386  AC A0A0G4ECT7.1
#=GS A0A061J7V9_TRYRA/489-561  AC A0A061J7V9.1
#=GS A0A0W8CV57_PHYNI/361-629  AC A0A0W8CV57.1
#=GS A0A0M9G3M3_9TRYP/539-608  AC A0A0M9G3M3.1
#=GS X6MRZ3_RETFI/270-499      AC X6MRZ3.1
#=GS A0A0G4IVG2_PLABS/332-537  AC A0A0G4IVG2.1
#=GS A0A422Q7Q1_9TRYP/369-492  AC A0A422Q7Q1.1
#=GS W4FZ70_9STRA/317-544      AC W4FZ70.1
#=GS A0A061J7V9_TRYRA/369-492  AC A0A061J7V9.1
#=GS A0A0G4EQ48_VITBC/131-176  AC A0A0G4EQ48.1
#=GS X6N209_RETFI/83-179       AC X6N209.1
#=GS Q4Q0G6_LEIMA/534-603      AC Q4Q0G6.1
#=GS A0A662XLL7_9STRA/1-306    AC A0A662XLL7.1
A0A6A3NVG4_9STRA/393-678             ........................a-MTQMIVREMRLFRDQFLAAEGD..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-AAVVGE.RPTIE...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLSRRALKMIAVLGL--...--....--NLTAEG....pSSNVT...SP...TVSET.rGSDReg..............ptiKGNG..........................K-Tepsda.....................................................................................................................................................................................vatfdkPTSTsaepgttaelvaqpltvqirpadv...........qssaatssgqaargivggagrgrgKRGL.........................................ENKN.VNL..........TSPRKPkrprtfside.......vavdemmrasgPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A0G4GFE1_VITBC/163-209             .......................va-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........----DP............................KDEL...NP.IAPCGVCDEWLQKIQE.....ESPGFSIVTFTTS.ECNEI------rer...............
D0N437_PHYIT/361-620                 ........................a-LTQMIVREMRKFRDQFLAAEGE..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..-AAELGG.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL--...--....--NLTAGG....nSSSVT...SP...TASED..T---...................GDDA.........................kRKEpsqgasfdktasts...................................................................................................................................................................tapaelhvveaanpqV--Lsvrvrpaavqsslssaat.......................nnstvaaragrgrgrgrgKREL.........................................ETKN.ANL..........TSPRKP............................K---...RPrTFSFDEVAEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQIM..................
K3X7R0_GLOUD/360-635                 ........................a-MTQTLVKEMRIFRDQFLQAEGE..-..--..GEVGNFWLRKS.RKPVLAVLL..IEKE..---DAQG.VKRLI...................................................VHRGMNCEVSMPTGSLCAERNAIGSALASDPTLKRRALKMIGVLSL--...--....--NLEGGG....gSSVQK...RE...ETTTS..VSTT...................FADIphvgkf..............qisklkE-Eatttetttlrg..........................................................................................................................................................................dneeasdlgvtA--Varsqavsatsin...................................vtgasslfirspKRRL.........................................EVEN.SNY..........QSPRKPkrprtfscddt......sveallsasesKTDR...NP.LAPCGACKEWLVKIAE.....ANPAFRVVTFDNS.RCRSVYVNQIM..................
S9TLD4_9TRYP/400-468                 ......................lgv-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTWS...........................................................VREV.........................................FVYG.L--..........----NP............................KKES...NP.LFPCGVCENMLQKVNSdiskhYGNEATLFMFDAT.KPHKVVYLPV-a.................
A0A3M6VVK1_9STRA/352-645             ........................a-MTQMVVREMRMFRDQFLSAEGE..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-ATVAGE.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNLa.aDD....IVSPSPSKytkhhNATQD...DD...KKKKRkpSQVQ...................----..........................--Agatldettstasepgs...............................................................................................................................................................iatllqsvglqlpvqirPTSVqcsskvdkaliptdetvq.......................hsangtgqgqgcgnrgreE--M.........................................NVNL.VSS..........RKPKRPrtfsfdkva..........meemirgstPLDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYISQI-i.................
T0RET2_SAPDV/307-526                 .....................plvl----RLVDEMKAFRDCFVDGQH-..-..-L..GEVGSFWLRKS.RKPVLAILL..IQKT..---LPNG.ETALV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLHRNALKMIGVLSV--...-N....LAPSSSTTal.plPRTVS...LP...TPIMP..TVRA...................AADCsspkakkp.........krprtfscdGTT................................................................................................................................................................................................PAVA...........................................................SALA.........................................EISA.P--..........---KKEv.........................paPEDR...NP.LGPCGACNEWLLKIAE.....ANPSFKIITFGSM.ECDSIYVHQ--ll................
W2YLS7_PHYPR/372-640                 ........................a-MTQMIVREMRKFRDQFLAAEGE..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..-AAELGG.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNLt.aGG....NISVTSPT.....ASEDT...AD...DKKEP.sDGAT...................FDKK..........................TSTa.............................................................................................................................................................................................vePANSqvlpvrvrpaavqssrss.......................aavnnlsvddagrgrgrgKRAL.........................................ETKN.ANL..........TSPRKPkrprtfsfde.......vaveemmrasaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A1E7F7I9_9STRA/650-893             .......................pv--VGQVVKEMKRFRDDFMKILSN..NseHS..NEIRAFWLRKT.HKPVIAVLA..VQTT..-------.DGKIK...................................................LYRGTNMEVSMPTGSLCAERNVIGTALADNPSLRRQDLKVIAVLAVPN..pKQ....PQNVTSTG.....SSGIP...RP...QSTTS.iGSMV...................SATL..........................EDEsshskivssrkssfggedewiv...................................................................................................................................................qehigsnakqtvpildnlnlpldPSAEsqs.....................................................stpVRRI.........................................YLYN.KPQ..........HQTRKQrrtv....................vvhsDADI...NP.LRPCGACNEWLKKV--.....-------------.-----------gifd..............
W4FWW5_9STRA/333-560                 ........................p-LVARAVDEIKAFRDQFVQGEHL..-..--..GEVGQFWLRKS.RKPVLAVLL..VEKR..---TSSG.DVQVV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRQSLKMIAVLSVSLh.pLKlappPPPSLSST.....SLLLP...AP...PALIL..AHATt................ttVTTAvea...................spktGRK................................................................................................................................................................................................PKRP...........................................................-RTIscdas..............................vpsiqaALDA.VDA..........SAAT--............................EKDL...NP.LAPCGACNEWLLKIAE.....ANPSFKIVTFDSI.DCDSVYIHQ--ll................
V5B3J9_TRYCR/369-492                 ........................n-IVDLRKEPEGSFLSKLCPIIMS..F..RQ..KNAHVSWRKKDpNRPVVTSLItyIDPE.eCDCQVDC.SGRGRppalikpngrege........................ekhprstwctctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
A0A2R5GYM4_9STRA/464-686             .......................ec---RQVVDEMRKYKHEFVQAKAA..G..SL..QELSAFWLRKT.RKVVLSVLM..VHMD..------N.EEEPR...................................................FYRGMNLEVSMPTGSLCSERNVIGTALASNQTLGRREFRYIAVLSMTL...-D....PPAPALPP.....SPSRH...TV...SRADN..STLA...................MDVSsrant................pqpnlGR-................................................................................................................................................................................................STSS...........................................................RRSItdttpe.............................nspllrPMSA.TNT..........GTNSRF............................QGEL...NP.IQPCGACMEWLKKIAE.....VNPTFKVVTFPNS.DCHEAFVQEI-g.................
A0A3R7G344_9STRA/354-598             ........................t-MTQKVVHEMRLFRDQFLAAEHE..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-ATVAGE.QPTII...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRSLKMIAVLGLNL...AE....FATSTSNE.....--VLP...IR...IHLGS.aGSIQ...................SASAatktepqvp.......sipiprvnggG-Gtgrgkrass..............................................................................................................................................................................enknanllsP---...........................................................----.........................................----.---..........---RKPkrprtfsfde.......aaveqmvragsAPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYIKQL-m.................
C1N795_MICPC/486-700                 .........................AIISRMVDEMKKHRDAYVAAASE..K..-T..NELGAFWLRKT.RKPVLAVLC..VRKK..GKTGRGH.----E...................................................FYRGVNLEVSMPTGSLCSERNVIGTALACDPTLRRADLFGVAVLSLKK..tGG....EGSGSGNAq...kGGVINggvRD...GGTAP.pTPVP..................gSSFA..........................GGA................................................................................................................................................................................................SRNA...........................................................SYAN.........................................DLSG.LGS..........GPTCRPv..........................aEDDL...NP.LHPCGACKEWLYKIAE.....VNPGFKVVMFTDA.SCEEVFVKTV-g.................
W6L9Z6_9TRYP/266-396                 .......................qv--VPLAKEPADSFLWKVTRLIQG..F..RD..GHAHCSWRKHNpSRTVVTSVLtyVDVR.aCGCGGITpEAEEEeegerggaaalppipp..................ekdigfparswcscprrWEVGVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lgv...............
A0A5A8DK55_CAFRO/420-820             ..................saggaas-----------------------..Q..PM..HDLADFWMRKS.KKPVLAVLL..VRWP.eSLRARHG.LPELE...................................................TFRGINLEVSLPTGSLCSERAAIAAAVAQRPFLRREHCVAIAVLSASLvpaSH....WSRGAAAA.....AGAAT...AA...ATAVSgpASPG...................APTA..........................GTPrapepsspagrargsgwpskcgcassacaspdkrqpgsngapfdgrrllhagasqgevshgielelagqmpdqaevgsclgfveapfgccyddvfealaqeggtvlrrrggrdaarragakaaaslhpgppatadgcdgcadeaccdthagagpgseelqasgtdalgalpgfgrpfplgspgspqramslsPSCE...........................................................MSEL.........................................PDDS.AEA..........AKARSRglg.....................agvaASDVv.sNP.LPPCGSCSEWLKKINE.....VQPDFRVLMFRDT.SCTTAIVRSV-e.................
A0A0G4GFE1_VITBC/70-165              ......................plk----RLVDEMRRFVNDWKSFEAA..-..--..GEMDPFWHRKS.SKTVLAVVM..VVNK..-------.SGQEM...................................................FYRGMNSEISLPSGSNCAERSAISTCISNSLDVRRSDFRAIAV-----...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------ad................
W7U454_9STRA/578-921                 ......................ara---RLVAQEMLRYKEEVLLHYRQ..G..LC..ADLSTFWLRKT.EKPVLAVLL..VQKD..-------.RARPL...................................................LYRGCNMEVSMPTGSLCAERNAIGSALAADLTLKRRDLKVVAVLSVSF...GK....NGNTGGGGgg.gdGGRKP...EG...TAKAL.dAVFA..................sIDTAprva..................sqttD-Rnhsysdsctghsignaqprgllgprkgdagasertggsmmasvgdqegpwtpssrr...............................................................................tgaqeevfdglspprttiirsysvkdlngcgqdgafgkpspaecrgrphassmdsldPKSSk.........................................................sT---.........................................----.---..........-----SpiiplsnlrvdgggrdqqgpgamtirveADDL...NP.LKPCGACMEWLKKIAE.....KNPEFRVATFTDE.ACRGIYTEFV-s.................
V5B3J9_TRYCR/489-561                 .....................smgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTSA...........................................................IREI.........................................FVHG.EML..........GSKKDP............................----...NP.LFPCGVCENMLRKVTRdvhdaYGGDVVLYMFDSTvNPKKLVYLPIN..................
A0A024TN09_9STRA/318-550             ........................p-IVTRLVNEVKSFRDQFVQGEHL..-..--..GEVGQFWLRKS.RKPVLAVLL..IEKL..----VDG.TPTIV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRQSLKMIAVLSVTL...HS....HPKQVAMA.....SAAQP..pCS...STA--..--LP...................IDAPppvlvnvpssi....qpsnverspkaGRK................................................................................................................................................................................................PKRP...........................................................-RTIscdas..............................vpaiqaALTAvDAA..........TAMAKA............................EKDL...NP.LAPCGACNEWLLKIAE.....ANPSFKIVTFDSI.DCDSVYIHQ--ll................
A0A0S4IPY9_BODSA/226-297             ....................amgla-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................-TCN...........................................................LREI.........................................FVHG.DM-..........HNNEDP............................----...NP.LFPCGVCENMLRRITHdvqkeYGGDVTLYMFDQVrEPKKLVCIPVQ..................
A0A1V9ZMX0_9STRA/308-518             .....................fllr-----LVSEMKAFRDCFLEGQH-..-..-L..GEVGSFWLRKS.RKPVLAILL..IQKK..---LPNG.DITTV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALASDPTLHRNALKMIGVLSVNL..aPP....SPPQTELM.....PPQI-...TP...SVHSN..GSD-...................----..........................SSS................................................................................................................................................................................................PKSKkpkrpr..............................................tfscdgtTPAV.........................................ALAL.DSI..........SNPKKE............................AVDR...NP.LGPCGACNEWLLKIAE.....ANPSFKIITFGSM.ECDSIYVHQ--ll................
A0A329SQ63_9STRA/361-647             ........................a-LTQMIVREMRKFRDQFLSAEGE..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..-AADIGG.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL--...--....--NLTAGG....aGSSVT...SP...TASED..T---...................GDDA..........................KKKepshgatfdkatststa.............................................................................................................................................................taelvgpanpqvlpvrvrPASVqsslssaavnhstpaq..........................rradavgtgrgrgrgrgKREL.........................................ETKN.ANL..........TSPRKPkrprtfsfde.......vaveemmrasaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
Q4CXE8_TRYCC/489-561                 .....................smgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTSA...........................................................IREI.........................................FVHG.EML..........GSKKDP............................----...NP.LFPCGVCENMLRKVTRdvhdtYGGDVVLYMFDSTvNPKKLVYLPIN..................
X6LM34_RETFI/14-136                  .......................kd--VQKIVYEMERWKDDFVIKMKA..P..-K..SEIETFWLRKS.FQPILAIVV..IQKP..-------.NEPIE...................................................YFRGVNMEVAMSTGSLCAERNAIGSAFVSDPSIRREYFKMVAVLQMPN..lPS....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------ttrmskldrelspqpsgv
A0A1Q9E3H3_SYMMI/62-150              .........irlalhemrtyladwq-----------------------..-..-A..STKDVFWQRKS.NKAVLSILL..CRSE..-------.SGDWC...................................................TYHGMNTEVSLPSGSVCAERAAIVR-AASDF-RHAKDIVLIATL----...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------d.................
M4BQJ0_HYAAE/354-656                 ........................a-MTQRIVVEMKTFRDQFLAAEGQ..-..--..GELASFWLRKS.RKPVLAVLL..IEKA..-ASRSNE.SPTVV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNLa.gGD....IGSSDLVT.....GSTPL...IS...TDQSE..ERVQ...................EDGK..........................--Teeellqvhtsavttfveptlvsgk................................................................................................................................................sgskttadvevavepdriqwtvsgP--Rlsedegakglilnde............................cgqhcrasegcghgkrS--Reh.....................................vnEVTS.RSL..........TKPKRPrtfscdeli..........sdsmresrtLPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVITFDNA.HCRHVYINQI-i.................
A4IE07_LEIIN/127-253                 ........................s-IIDLKKEQPNTFFSNATRMIQS..F..CR..THAHCSWRKHDpSRPVVTSVLtfVDVN.kCHCHLNG.DNPENtheehidapipadie.....................emgtpsgswcqcmrrGVIAVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lgv...............
Q38A89_TRYB2/370-496                 ........................r-TLDLKREGAKSFFTNITLEILQ..F..RS..TMADCSWRKKDpMRQVVTSLMtyVDHK.kCHCNVTC.GSRRHwsmhkpalssngngm....................snatfpdhswctcprsTVMAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mg................
S9TLD4_9TRYP/274-402                 .......................cv--VNLSKEPPESFFSRVTNIIKS..F..SVegRNAHCSWRKNDpTRPLVTSVFtyVDVN.tCRCGDVS.RVLNVdddasvraeldpvte.....................niglpprvwctcarhYVVAVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lgv...............
W6KP16_9TRYP/361-493                 ........................k-VTRLSKEPADSFLVRVTDIING..F..RA..LHAHCSWRKHNpHRTVVTSILtyVDVR.gCQCGLLP.PGSPLrggdedddnafpalpsip...............pgaaiglperswctcarrWEVGVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lgv...............
A0A024GRI2_9STRA/349-596             ........................p-MVQLVVQEMCIFRDQFLQAQGK..-..--..GEVESFWLRKS.RKPVLAVLL..VEKH..---EQDG.SVRLL...................................................VHRGMNCEVSMPTGSLCAERNAIGSALAQDPTLCRRSLKMIAVLGVNL..lES....KTSVITTTrtitdSCELN...-P...PRTES.lS---...................-DNVynni.................ithksQ-Neglklssiratcqmt.................................................................................................................................................................lsrafecereaghalsPSRP...........................................................KR--.........................................----.---..........-----Prtfsiddy...........tigesqlskIGDR...NP.LAPCGACKEWLMKIAE.....ANPSFRVITFENA.DCHNVYISQIM..................
A4IE07_LEIIN/250-318                 ......................slg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--V................................................................................................................................................................................................PTWG...........................................................VREV.........................................FVHG.R--..........-AAKEP............................----...NP.LFPCGVCENMLRRVTKdvlahYGGDVTLYMFDAT.TPRKIVFLTI-p.................
Q4CXE8_TRYCC/369-492                 ........................n-IVDLRKEPEGSFLSKLCPIIMS..F..RQ..KNAHVSWRKKDpNRPVVTSLItyIDPE.eCDCQVDC.SGRGRppalmkpngrere........................ekhprstwctctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
B7GB54_PHATC/685-977                 ........................p-YRHLVIDEMKAFQAEMIKTLQG..Q..--..NDIHRFWLRKT.HKPVLAVLL..VEQE..-------.-GQPI...................................................LYRGTNMEVSMPTGSLCAERNVIGTALAANPSLRRQDLKMIAVLAVPW..qEK....LTDMGSAGt..lrSSEEP...FP...ALASS.sASLTsi...............mcTTTLe.......................sgE-Grktsigseheewilssapaggedgstgattnktrlp.......................................................................................................................pakselgnsfdlvdsgvpssssgvastapdrqpnddiPSTP...........................................................VRRI.........................................ALFS.RSG..........TVARKSqqav...................vlvqsTRDL...NP.LPPCGACNEWLKKIAE.....CNPYFCVLTFTDA.ECHGVYCTPCQ..................
A0A023AZW5_GRENI/26-125              ...........qdlpedtkflvghm-----------------RQFAQD..Y..QA..AKPDTYWHRKS.GQVVLAVLL..LRIH..-------.-GKLQ...................................................TVRGINSELSLPSGSVCAERAAIAAALAQHLSIARSDFVSIAVLA---...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------pnna..............
Q4DNI7_TRYCC/489-561                 .....................smgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTSA...........................................................IREI.........................................FVHG.EML..........GSKKDP............................----...NP.LFPCGVCENMLRKVTRdvhdaYGGDVVLYMFDSTvNPKKLVYLPIN..................
A0A6A3Y6C9_9STRA/401-686             ........................a-MTQMIVREMRLFRDQFLAAEGD..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-AAVVGE.RPTIE...................................................VQRGMNCEVSMPTGSLCAERNAISSALASDPTLSRRALKMIAVLGL--...--....--NLTAEG....pSSNVT...SP...TVSEI.rGSDReg..............ptiKGNG..........................KTEpsdav......................................................................................................................................................................................atfdkPTSTsaepgttaelvaqpltvqirpadv...........qssaatssgqaargivggagrgrgKRGL.........................................ENKN.VNL..........TSPRKPkrprtfsmde.......vavdemmrasgPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A0M0JEH7_9EUKA/250-364             .....................eekg-----LVDEMVQYKRQFEAVRDS..N..-T..HELGTFWLRKT.GKAVLAVLL..TKSP..-------.LGELT...................................................FWRGMNVEVSMPTGTLCAERNAIGNALAGDHSVHRRDMLAVAVLSVTL...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------sppkhevtdqaler....
A0A6G0XQD2_9STRA/318-536             ........................p-LVAQLVDQVKTFRDRFLEGQS-..-..-A..GEVGTFWLRKS.RKPVLAILL..IQKK..---NSDG.EFETI...................................................FHRGMNCEVSMPTGSLCAERNAIGSALANDPTLHRQSLKMIAVLSVNL...TQ....QAVPTTPL.....LPPLP...PP...LLALP..PPLVks...............ssN--As........................vDQS................................................................................................................................................................................................PKTRkp.......................................................krPRTIscd..................................asvpAVQA.ALE..........SVDAKV............................EKDR...NP.LAPCGACNEWLLKIAE.....ANPSFKIITFDSI.ACEKVYIHQ--ll................
A0A0G4ECT7_VITBC/249-344             ................plkrivdea----------RRYVNEWKSL---..-..-E..GQMDSFWHRKS.SKIVLAVVM..VVDK..-------.NGQER...................................................FYRGMNSEISLPSGSNCAERAAISACISNSLTVRRSDFRAIAVV----...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------dpk...............
Q4DNI7_TRYCC/369-492                 ........................n-IVDLRKEPEGSFLSKLCPIIMS..F..RQ..KNAHVSWRKKDpNRPVVTSLItyIDPE.eCDCQVDC.SGRGRppalikpngrere........................ekhprstwcnctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
A0A0G4EQ48_VITBC/40-132              .......plkrlvdearryvnewks-----------------------..-..LE..SQMDSFWHRKS.SKIVLAVVM..VVEK..-------.-GRLR...................................................FYRGMNSEISLPSGSNCAERSAISTCISNMLTVRRSDFRAIAVV----...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------d.................
A0A1Q9E3B0_SYMMI/124-214             ............diafavmelkefv---------------------AE..W..QE..AATDKFWQRKS.HKVVLAVVC..CARD..-------.DGSLV...................................................AMRGMNTEVSLPSGSLCAERAGIAR--AATEFFHANTIKVIAVV----...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------dp................
A0A1V9Z9N5_9STRA/301-522             ........................p-LVERLVAEMKAFRDCFVQG---..Q..HL..GEVGSFWLRKS.RKPVLAILL..IQKR..---LPTG.ELTTV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLHRNALKMIGVLSV--...NL....APPMSAPQ.....IPALP...RA...ESLP-..TPLTp.................tVHAAp.......................teASS................................................................................................................................................................................................PKAKkpk.....................................................rprT--Fscdgt..............................tpavasALAS.VAM..........PKK--Ei.........................ppPEDR...NP.LGPCGACNEWLLKIAE.....ANPSFKIITFGSM.ECESIYVHQ--ll................
A0A1X0NLM5_9TRYP/499-570             ......................mgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTNA...........................................................VREV.........................................FVHG.ENK..........GIQKDP............................----...NP.LFPCGVCENMLRKVTRdvheaHGGNVMLYMFDSTeDPKRLVSLP--ln................
Q38A89_TRYB2/493-566                 .....................asmg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--L................................................................................................................................................................................................PTCA...........................................................VREV.........................................FVHG.EHQ..........GSKKDP............................----...NP.LFPCGVCENMLRKVAHdvleiHGGDVMLYMYDSThNPKRLVYLPI-t.................
A0A662WMZ3_9STRA/17-327              ........................a-MTQMLVREMRLFRDQFLAAEGE..-..--..GEVSSFWLRKS.RKPVLAVLL..IEKA..-STVKGE.PPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIGVLGLNL...GA....GGEKPATTp...tSVAMN...GN...EGEAG..SQVGq................kaVES-..........................--Saglssptfae...........................................................................................................................................................................tpasrastsseP--AtaasrpatellpvqirpleegssvqsspeavasrdapaasssnahsgrsngrrggrgrgKRAL.........................................LVPP.ENKna......nlTSPRKPkrprtfsfde.......vaveqmmrvaaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
H3GUA2_PHYRM/361-650                 ........................a-LTQMIVREMRMFRDQFLAAEGE..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-AAVAGE.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNL...SG....SGSNVISP.....TPSET...RG...SEREG..G-AV...................GDDG..........................NKKpseaqaa..................................................................................................................................................................................agptfdqP--Tststagptapalpvrirpacvqsspe.......ppdankpaerqgsvggvgrgrgrgrgKRAL.........................................ENKN.ANL..........TSPRKPkrprtfsfde.......vaveemmrasaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
W2PRR7_PHYPN/372-640                 ........................a-MTQMIVREMRKFRDQFLAAEGE..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..-AAELGG.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNLt.aGG....NISVTSPT.....ASEDT...AD...DKKEP.sDSAT...................FDKK..........................TSTavepans.................................................................................................................................................................................qvlpvrvrPTAVqssrssaavnnl...................................svddagrgrgrgKRAL.........................................ETKN.ANL..........TSPRKPkrprtfsfde.......vaveemmrasaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A2P4YKF2_9STRA/355-651             ........................a-MTQMIVREMRMFRDQFLSAEGE..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-AAVAGE.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL--...--....--NLTA-G.....GSIIT...SP...TASER..DGVT...................GDDV..........................KSKepsdarasapfdkptstatep.....................................................................................................................................................spqilavrirpasvqtsqeqssP--Ssaavknspaafspnalaa.......................eqldggggadgrrsrgrgKRGP.........................................ETKN.TNL..........TSPRKPkrprtfside.......iavegmmhastPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A0M9G3M3_9TRYP/416-541             ........................n-VIDLKREDDDSFFIVVTRMILN..F..RT..HHAHNSWRKHDpTRPVVTSVLtfVDVN.eCHCHRNG.GDANNtieehidavipddta.....................vvgvpsgswcncprrAVIAVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lg................
A0A0N7L3D3_PLAHL/339-619             ........................a-MTQMIVNEMQQFRDQFLEAEGQ..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..--AIDGG.RPTIV...................................................MQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNL...TA....GGNTSPTT.....SDDRV...QD...THTIA.eTIET...................TDSA..........................TTNrtvdttkaqisavqtcrsh..........................................................................................................................................................seqssfssvltvnstflsiQ--Narqhddvai.........................................ekergqtrrKRQL.........................................RITN.ANL..........RSPRKPkrprtfsfdd.......maviemmrasePLDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVITFENA.RCRNVYINQL-m.................
K2NCU0_TRYCR/488-560                 .....................smgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTSA...........................................................IREI.........................................FVHG.EML..........GSKKDP............................----...NP.LFPCGVCENMLRKVTRdvhdtYGGDIVLYMFDSTvNPKKLVYLPIN..................
C5KHT8_PERM5/69-173                  ..ptavlanklrdymerttadgfqp-----------------------..-..--..---DPFFHRKS.GKLVLSMLH..VRME..-------.DGRDE...................................................FFEGINGEVSLPTGSLCSERAAIAHARSVHPRINRGMFMGIAVIDVPT...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------kmndghtd..........
X6NWX0_RETFI/13-193                  ............qvgnrnvlaaeaf-----------------------..-..--..-----------.-QPILAIVV..IQKP..-------.NEPIE...................................................YFRGVNMEVAMSTGSLCAERNAIGSAFVSDPSIRREYFKMVAVLQM--...--....-PNLPSTT....rMSKLD...RDpppLRLEK..AQHH...................----..........................--Y................................................................................................................................................................................................SAST...........................................................HRNQ.........................................AMLS.QSNpfg....knkL----Spsthl.................kvdedgLEDQ...NP.RGPCGACAEWLKKIAE.....VNPNFKIVTFSDV.KL---------akflff............
C1EFE8_MICCC/391-596                 ........................r-LVTGMVQEMKKHRDVFLSMSHS..K..--..HELGEFWLRKT.QKPVLAVLC..VRRRrdGPDDAAHgDAKPQ...................................................YFRGVNLEVSMPTGSLCSERNAIGNALASDPALRRKDLFGIAVLSLGK...GD....IGATSGGGv...gGGAMS...RE...SSFVN.lAQLA...................AGNG..........................GDD................................................................................................................................................................................................-LSL...........................................................CRPV.........................................TGGG.G--..........-----G............................RGDL...NP.LKPCGACKEWLLKIAE.....VNPGFKVLMFGDV.SCDDVYIKNV-s.................
D7G3E7_ECTSI/557-885                 .........................AYTRQAFDAPAG-DANGEAVVGG..D..TR..DDLASFWLRKT.KKPVLAVLL..VQKK..-------.GGRPQ...................................................LFRGTNMEVSMPTGSLCAERNVIGSALTSDLSLLRRDIKAVAVLSVAH..lGG....PPASTATT.....AAAVP...ID...ERKEG..ASLTgi...............taVDSG..........................GGRsgwpgaagmgsavgssl.............................................................................................................................................................ttscapsplsltpamkvsPKSAllrtetgagaedke...............................rlegvrqvrrktkvV--RsiastpkrgvgsggiaaggwekspltdsgggggggrgdgggGMYS.DDQgggg.gsnhhRHPRTSrssi....................vahvPPETlcsNP.LKPCGACMEWLKKIAE.....VNPDFKVITFTDS.RCGGVYIEDV-a.................
A0A485L9A1_9STRA/319-551             .....................plvv----ELVEQVKAFRDQFLEGE--..-..SR..GEVGTFWLRKS.RKPVLSMLL..IQKK..--DPIDG.TLKTV...................................................FHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRSSLKMIAVLSVNLr.pPA....LQNTPQKG.....----P...SN...GMNPV..ASLPplllpptlhkstsiasmssITSV..........................EHS................................................................................................................................................................................................PKTRkp.......................................................krPRTIscd..................................asvpAIQA.ALQ..........VVEAKL............................DKDR...NP.LAPCGACNEWLLKIAE.....ANPSFKIITFDSM.ACENVYIHQ--ll................
A4HQB2_LEIBR/418-544                 ........................n-IIDLKKEHPNSFFSNATRMIQH..F..CR..TRAHCSWRKHDpTRPVVTSVLtfVDVN.rCHCHRNG.DNPYNtheehieasfpsdie.....................amgtpsgawcqcmrrGVIAVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lgv...............
A0A1X0NLM5_9TRYP/378-501             ........................d-VIDLKKEKEGSFLSFVTPIILS..F..RH..ENAHVSWRKKDpQRPVVTSLItyVDPA.eCSCRSNE.GFLSRgsfvrhhlpqkgt........................ekypenswcscprsFVIAVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
Q4Q0G6_LEIMA/412-537                 ........................t-IIDLKKEQPNTFFSNATRIIQN..F..CR..THAHCSWRKHNpSRLVVTSVLtfVDVN.kCHCHLNG.DNPEDthderidapitadie.....................amgtpsgswcqcmrgGVIAVNYELSTPSGSRCSEQNAMGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------lg................
A0A3R7NP46_TRYRA/368-489             ........................n-IVDLIKEPEGSFISSVCPIIMS..F..RQ..THAHASWRKKDpNRPVVTSLItyIDPD.eCHCKADA.GQRARypalssegqkwq..........................kyprnawctcnrsYVIAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
A4HQB2_LEIBR/540-610                 .....................aslg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--V................................................................................................................................................................................................PTWG...........................................................VREV.........................................FVHG.M--..........ASKKEA............................----...NP.LFPCGVCENMLQRVTKdvlahYGGDITLYMFDAT.TPRKIVFLPI-p.................
A0A0M0JEH7_9EUKA/354-416             ..............khevtdqaler-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........--TTSPd..........................dEVAL...NP.LDPCGACMEWLRKIAE.....VNPDFKVLTFTST.SCEKVFITPI-g.................
K2NCU0_TRYCR/368-491                 ........................n-IVDLRKEPEGSFLSKVCPIIMS..F..RQ..KNAHVSWRKKDpNRPVVTSLItyIDPD.eCNCQVDC.SGRGRpptlmepnsrege........................ekhprstwctctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
A0A448YX44_9STRA/589-863             ........................s-LVKRVVEEMKNFRDDFLKILSNssD..DS..NDIRAFWLRKT.HKPVIAILA..VQPP..-------.NGELK...................................................LYRGTNMEVSMPTGSLCAERNVIGTALADNPSLRRQDLKMVAVLAVPN..pKQ....LQASTSVG.....--GLP...RS...QSLNS.vASLV...................TATV..........................EDEsslgrpsrksslggedewivqdhsif............................................................................................................................................agqdnapvfvdkktlssgqsdpedvqP--Natldss...............................................sqsstpVRRI.........................................FLYN.KPQ..........KQTRKQrrav....................vvhsGHDI...NP.LRPCGACNEWLKKLAE.....TNPYFTVVTFTDS.ACNGVYCTPC-e.................
A0A225VY69_9STRA/350-624             ........................a-MTQMIVREMRMFRDQFLAAEGE..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-AAVAGE.RPTVV...................................................VQRGLNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL--...--....--NLSASG.....TSSIT...SP...TASER..DEVT...................GDGGk.......................tnEAG................................................................................................................................................................................................PTTDkttststdhdlatsspqklparvrp........apvqisqtqraasvdgagrgqgrgrgKRES.........................................EAKN.ANL..........TSPRKPkrprtfsfde.......maveemvrasgPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A067CZ46_SAPPC/307-527             ........................p-LVQRLVDEMKSFRDCFVDGQH-..-..-L..GEVGSFWLRKS.RKPVLAILL..IQKT..---LPTG.ETALV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLHRNALKMIGVLSVNL...--....--APPSTS.....TSSLP...LP...RTVSL.pTPITpt...............vrAATDcsspkakkp........krprtfscdGTT................................................................................................................................................................................................PAVA...........................................................SALA.........................................EISA.---..........--PKKEv.........................paPEDR...NP.LGPCGACNEWLLKIAE.....ANPSFKIITFGSM.ECDSIYVHQ--ll................
K0SZS5_THAOC/573-878                 ......................evs----RVTVEMKAFRVEFLQSVKE..G..GR..SDLREFWLRKT.RKPVLAVLL..VQKP..-------.NHEPV...................................................LYRGTNMEVSMPTGSLCAERNVIGTALASDPGLKREDLKMVAVLSVRM..pKD....RTYRNILPp..pgGMSFC...QP...TATATssSDLA...................-KEV..........................EARpkqdvgmkktlsmssftsiaeg...................................................................................................................................................lpspencvneswemdllsgfdktPTAEeaayvetpkegmlipeln......................lrnrpsdasdgsvsgsstpKRRI.........................................ALYK.KKN..........RNKAGGkrqtlvvq...........qleadligfLQDM...NP.LKPCGACNEWLKKIAE.....SNPHFKVLTFTDE.NQAGVYVMPCQ..................
A0A0L0FHB9_9EUKA/30-302              ............csvaretfqpwpc------------------HIVED..-..GD..SEINEFWLRKT.KKPVLSVLR..YTKP..-------.GEESQ...................................................YVYGMNIEVSMPTGSLCSERNAIGTAIASDPSLKRKDFDMIAILSISL...PE....LANASTP-.....-AVTP...NP...ARRDRrsTELD...................TNQT..........................DTNqtqtslttehgmlkgskgsah.....................................................................................................................................................tlanvlsdvaqnagptttdgtkS--Aatskppgsqplmnavpp.........................rgfyedclaplkrfnsdLQAL.........................................TIGN.EEFi........wP--QEK...........................kRTEL...NP.LDPCGSCMEWLRKIAE.....VNPDMKIVTFDSS.SCERLYVKNV-i.................
A0A3R7NP46_TRYRA/485-558             .....................asmg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--L................................................................................................................................................................................................PTSA...........................................................IREI.........................................FVHG.ENR..........RAETDP............................----...NP.LFPCGVCENMLRRVTRdvydmYGGDVVLYMFDSTvNPKKLVYLPIN..................
A0A422Q7Q1_9TRYP/489-561             .....................smgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTCA...........................................................IREV.........................................FVHG.ENL..........GAQTDP............................----...NP.LFPCGVCENMLRKVTRdvydtYGGDVVLYMFDSTvNPKKLVYLPIN..................
C5KBD0_PERM5/68-174                  sdptavlanklreymerttadgfqp-----------------------..-..--..---EPFFHRKS.GKLVLSMLH..VRME..-------.DGSDE...................................................FFEGINGEVSLPTGSLCSERAAIAHARSVHPRINRGMFMGIAVIDVPT...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------kmndghtd..........
W6KP16_9TRYP/489-557                 .....................aslg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--V................................................................................................................................................................................................PTWS...........................................................VREL.........................................FVHG.S--..........------............................SEHV...NP.LFPCGVCDNMLQRVAKdvrtrYGGEIRLYMFDAT.VPSKVVSLP--ms................
G5AGH2_PHYSP/357-655                 ........................a-MTQMIVREMRIFRDQFLAAEGD..-..--..GEVASFWLRKS.RKPVLAVLL..IEKP..-AAVVGD.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLSRRALKMIAVLGLNL..tA-....EGPSSNVTs...pTASET...RG...SEREG.pATCT...................KDTK..........................GNGngkrdps.................................................................................................................................................................................daeatfdkPTSTstepgpelvaqpqpltvrirpageqss.....pernslslaaasprarshvggagrgrgKRGP.........................................ETKN.ANL..........TSPRKPkrprtfsmdd.......vavdemlrasgPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
V9EIB2_PHYPR/372-640                 ........................a-MTQMIVREMRKFRDQFLAAEGE..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..-AAELGG.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNLt.aGG....NISVTSPT.....ASEDT...AD...DKKEP.sDGAT...................FDKK..........................TSTa.............................................................................................................................................................................................vePANSqvllvrvrpaavqssrss.......................aavnnlsvddagrgrgrgKRAL.........................................ETKN.ANL..........TSPRKPkrprtfsfde.......vaveemmrasaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A0S4IPY9_BODSA/82-230              .......................rt--IDLSKLPASNFFKKVVKITLD..F..RG..SNAHKSWRKQDaTRPIVTSLItyVDST.tCFCQAHG.TISASqtpslgpmgrgssslsspqrqgstggtshyidasaaagaypenswcrcprkWELAVNYELSTPSGSRCSEQNCLGK-LAA-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgla..............
A0A6H5K1D9_9PHAE/552-610             ..................laapprg------------------AVVGG..D..AR..DDLATFWLRKT.KKPVLAVLL..VQKK..-------.GGQPQ...................................................LFRGTNMEASF-------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------nahg..............
W6L9Z6_9TRYP/393-461                 ......................slg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--V................................................................................................................................................................................................PTWS...........................................................VREL.........................................FVHG.AN-..........------............................VVNI...NP.LFPCGVCDNMLQKVDKdvrtrYGGEVRLFMFDET.VPSKVVYLPM-s.................
A0A5D6Y6H5_9STRA/303-621             ........................a-LTQALVHEMRVFRDQFLRAEGD..-..--..GEVGAFWLRKS.RKPVLAVLL..VEKQ..---DACG.ATRLV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALASDPTLKRRAMKMIGVLSLNL...GA....TPAAAAVA....tATSVA...TT...TTTTS..KTTA...................AETA..........................ASReplasphamfagiprvgalelstttettvvtaattaaavagvnsd.....................................................................................................dsvdgedggsdgattavasavasglahaattaatqtaqeaaaaaaaPSSP...........................................................KRR-.........................................RLHT.QNAn........yQSPRKPkrprtfsvddt......avetalaladnGRDR...NP.LAPCGACKEWLVKIAE.....ANPAFRVVTFENS.RCRSVYVSQIM..................
A0A0G4ECT7_VITBC/341-386             ........................v-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........----DP............................KDEL...NP.IAPCGVCDEWLKKLQE.....ESPTFSIVTFTTS.DCDEI------ler...............
A0A061J7V9_TRYRA/489-561             .....................smgl-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................PTSA...........................................................IREV.........................................FVHG.ENR..........RAQTDP............................----...NP.LFPCGVCENMLRRVTRdvyetYGGDVVLYMFDSTvNPKKLVYLPVN..................
A0A0W8CV57_PHYNI/361-629             .........................AITQMIVREMRKFRDQFLAAEGE..-..--..GEVAGFWLRKS.RKPVLAVLL..IEKP..-AAELGG.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGLNLt.aGG....NISVTSPT.....ASEDT...AD...DKKEP.sDGAT...................FDKK..........................TSTa.............................................................................................................................................................................................vePANSqvlpvrvrpaavqssrss.......................aavnnlsvddagrgrgrgKRAL.........................................ETKN.ANL..........TSPRKPkrprtfsfde.......vaveemmrasaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
A0A0M9G3M3_9TRYP/539-608             ......................slg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--V................................................................................................................................................................................................PTWG...........................................................VREV.........................................FVHG.M--..........NIKKEA............................----...NP.LFPCGVCENMLQKVTKdvmshYGGDVTLYMFDAT.HPRKIVFLTI-p.................
X6MRZ3_RETFI/270-499                 .......................kd--VQKIVHEMESWKDDFSIKMKA..-..PK..SEIETFWLRKS.YQPILAVVM..IQKP..-------.NEPIQ...................................................YFRGVNMEVAMSTGSLCAERNAIGSAFVSDPSIRREYFKMVAVLQM--...--....-PDLSSAA....kISKFD...RE...QSPQP..SYYC...................YH-FfffcfflflllfmhafppplrlekaqH--................................................................................................................................................................................................---Hys......................................................afmHRNQ.........................................TIFN.QSNpfgnrqsvdtKMNEKA............................PEDN...NP.RGPCGACSEWLKKIAE.....VNPNFKIVTFSDV.E----------litflff...........
A0A0G4IVG2_PLABS/332-537             ....................lhlgl------VEKMKERRQAFVLALRN..D..--..HELRAFWLRKT.FKPVLSVLL..VMKP..-------.GGVPQ...................................................YFSGMNMEVSMPTGSLCAERNAIGNALAQDPTLHREHFKAMAVLSVSM...GS....ADPSNGDSt...sTHHWH...TD...VASPPnsPTLA...................ADAW..........................DDR................................................................................................................................................................................................-RFN...........................................................IRPT.........................................RSQT.MRH..........--ATTQsv.......................spyLRAL...NP.INPCGACKEWLKKIAL.....VNPDFVVLTFPSM.ICDSVFVRPV-l.................
A0A422Q7Q1_9TRYP/369-492             ........................n-ILDLKKEPAGSFISTVCPIIMS..F..RQ..KHAHVSWRKKDpNRPVVTSLItyVDPE.gCHCQVNA.GQRARspalmssngrerq........................gkhpsntwctcnrsYVIAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
W4FZ70_9STRA/317-544                 ........................p-LVARAVDEIKAFRDQFVQGEHL..-..--..GEVGQFWLRKS.RKPVLAVLL..VEKR..---TSSG.DVQVV...................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRQSLKMIAVLSVSLh.pLKlappPPPSLSST.....SLLLP...AP...PALIL..AHATt................ttVTTAvea...................spktGRK................................................................................................................................................................................................PKRP...........................................................-RTIscdas..............................vpsiqaALDA.VDA..........SAAT--............................EKDL...NP.LAPCGACNEWLLKIAE.....ANPSFKIVTFDSI.DCDSVYIHQ--ll................
A0A061J7V9_TRYRA/369-492             ........................n-VVDLMREPEGSFILSVCPIIMS..F..RQ..THAHASWRKNDpNRPVVTSLItyIDPD.eCHCQADT.GQRAGspalmssgghkrq........................ekyprntwctcnrsYVIAVNYELSTPSGSRCSEQNALGK-LAS-------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------mgl...............
A0A0G4EQ48_VITBC/131-176             ........................v-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........----DP............................KDEL...NP.VFPCGVCDEWLKKLQE.....ESPMFSIVTFTTS.ECDAI------ler...............
X6N209_RETFI/83-179                  ........................q-ITYLLIKEMEKYLKEFHAKERE..-..--..DKMDPFWNRKS.FKSVLAVLM..VRKR..QDNDNNN.NNNNNnnnnn.........................................skqyvFYRGRNTEISLPVGSHCAERAAIV------------------------...--....--------.....-----...--...-----..----...................----..........................---................................................................................................................................................................................................----...........................................................----.........................................----.---..........------............................----...--.----------------.....-------------.-----------tlcq..............
Q4Q0G6_LEIMA/534-603                 .....................aslg-----------------------..-..--..-----------.---------..----..-------.-----...................................................------------------------------------------------...--....--------.....-----...--...-----..----...................----..........................--V................................................................................................................................................................................................PTWG...........................................................VREV.........................................FVHG.M--..........-AATEP............................----...NP.LFPCGVCENMLRRVTKdvlahYGGDVTLYMFDAT.TPRKIVFLPI-p.................
A0A662XLL7_9STRA/1-306               ........................m-----LVREMRLFRDQFLAAEGE..-..--..GEVGSFWLRKS.RKPVLAVLL..IEKP..-PEVKGE.RPTIV...................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIGVLGLNL...GA....GGEKSATTp...tPAAVN...GN...EEEAG..NQVGq................kaVESS.........................aG-Qssptfaetpasra.....................................................................................................................................................................stsnepvtaasrpaT--Ellpvrirpleegssvqsspesaasr.........dapaasssnahsgrsnvgrggrgrgKRALvppe................................dkngnL---.---..........TSPRKPkrprtfsfde.......vaveqmmrvtaPPDR...NP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m.................
#=GC seq_cons                        ........................s.....hhp..t.ahtphh.h..t.........tchts.Wh+Ks.p+PVlssLl..lph...........t.p.....................................................h.hGhNhElShPoGShCuEpNAlGp.LAs............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NP.LhPCGsCpphLhKlsc.....hssthhlhhFps..psptlhh....h.................
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