GenomeNet

Database: Pfam
Entry: MPM1
LinkDB: MPM1
Original site: MPM1 
#=GF ID   MPM1
#=GF AC   PF17234.3
#=GF DE   Mitochondrial peculiar membrane protein 1
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Jackhmmer:A6ZPQ6
#=GF GA   25.00 25.00;
#=GF TC   25.00 26.00;
#=GF NC   24.70 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   11791739
#=GF RT   A novel protein, Mpm1, of the mitochondria of the yeast
#=GF RT   Saccharomyces cerevisiae.
#=GF RA   Inadome H, Noda Y, Adachi H, Yoda K;
#=GF RL   Biosci Biotechnol Biochem. 2001;65:2577-2580.
#=GF DR   INTERPRO; IPR035187;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family contains  mitochondrial peculiar membrane proteins,
#=GF CC   found predominantly in Saccharomycetales.
#=GF SQ   77
#=GS A0A1D8PSE0_CANAL/135-304  AC A0A1D8PSE0.1
#=GS Q6BY44_DEBHA/158-338      AC Q6BY44.1
#=GS A0A1X7R817_9SACH/99-279   AC A0A1X7R817.1
#=GS C5E373_LACTC/104-260      AC C5E373.1
#=GS A0A1E3NUS1_WICAA/97-252   AC A0A1E3NUS1.1
#=GS A0A1G4KH39_9SACH/113-281  AC A0A1G4KH39.1
#=GS A0A1E3NLF5_9ASCO/108-284  AC A0A1E3NLF5.1
#=GS A0A448YGK4_BRENA/101-289  AC A0A448YGK4.1
#=GS A0A2V1AT82_9ASCO/114-293  AC A0A2V1AT82.1
#=GS A0A1G4MF31_LACFM/104-258  AC A0A1G4MF31.1
#=GS Q758B0_ASHGO/115-286      AC Q758B0.2
#=GS K0KQG7_WICCF/95-248       AC K0KQG7.1
#=GS C5M3Z9_CANTT/132-304      AC C5M3Z9.1
#=GS G3AI36_SPAPN/155-332      AC G3AI36.1
#=GS M7NT83_PNEMU/114-232      AC M7NT83.1
#=GS A0A1E4T4V5_9ASCO/99-264   AC A0A1E4T4V5.1
#=GS G8YBI5_PICSO/156-333      AC G8YBI5.1
#=GS G8BC20_CANPC/144-322      AC G8BC20.1
#=GS A0A1A0HH42_9ASCO/134-310  AC A0A1A0HH42.1
#=GS A0A2H1A7P6_CANAR/115-293  AC A0A2H1A7P6.1
#=GS G8ZT18_TORDC/131-294      AC G8ZT18.1
#=GS A0A1G4KL30_9SACH/104-263  AC A0A1G4KL30.1
#=GS A7TQM8_VANPO/115-287      AC A7TQM8.1
#=GS Q6FPA9_CANGA/100-283      AC Q6FPA9.1
#=GS A0A367XZE6_9ASCO/138-310  AC A0A367XZE6.1
#=GS A0A421JDK8_9ASCO/123-328  AC A0A421JDK8.1
#=GS A0A3F2XXM5_DEKBR/99-282   AC A0A3F2XXM5.1
#=GS G0V7N4_NAUCC/71-236       AC G0V7N4.1
#=GS A0A1V2LIH9_PICKU/97-268   AC A0A1V2LIH9.1
#=GS A5DSA9_LODEL/161-359      AC A5DSA9.1
#=GS I2H122_TETBL/83-281       AC I2H122.1
#=GS A0A0C7MXJ6_9SACH/104-263  AC A0A0C7MXJ6.1
#=GS A0A1E3PTH5_9ASCO/166-358  AC A0A1E3PTH5.1
#=GS A0A367Y8P4_9ASCO/138-310  AC A0A367Y8P4.1
#=GS A0A1E5RJJ9_HANUV/101-258  AC A0A1E5RJJ9.1
#=GS A3LQV0_PICST/189-371      AC A3LQV0.2
#=GS W6MJ79_9ASCO/141-312      AC W6MJ79.1
#=GS A0A2T0FFF7_9ASCO/68-109   AC A0A2T0FFF7.1
#=GS A0A2T0FFF7_9ASCO/102-202  AC A0A2T0FFF7.1
#=GS J7SBT7_NAUDC/101-271      AC J7SBT7.1
#=GS C4R4B9_KOMPG/139-241      AC C4R4B9.1
#=GS A0A1E4SJ09_9ASCO/146-323  AC A0A1E4SJ09.1
#=GS A0A1E3Q9H2_LIPST/286-331  AC A0A1E3Q9H2.1
#=GS A0A109UXJ7_9SACH/112-282  AC A0A109UXJ7.1
#=GS G8BXJ8_TETPH/115-299      AC G8BXJ8.1
#=GS Q6C365_YARLI/155-198      AC Q6C365.1
#=GS A0A0J9X913_GEOCN/106-259  AC A0A0J9X913.1
#=GS Q6C365_YARLI/185-303      AC Q6C365.1
#=GS W1Q9G8_OGAPD/111-264      AC W1Q9G8.1
#=GS A0A0J9X9F7_GEOCN/99-270   AC A0A0J9X9F7.1
#=GS A0A1E5RZL8_9ASCO/171-264  AC A0A1E5RZL8.1
#=GS J7RHG3_KAZNA/74-158       AC J7RHG3.1
#=GS S6EPY0_ZYGB2/131-301      AC S6EPY0.1
#=GS G8YMD0_PICSO/156-333      AC G8YMD0.1
#=GS Q6CLM4_KLULA/68-214       AC Q6CLM4.1
#=GS A0A1L0BAW6_9ASCO/127-301  AC A0A1L0BAW6.1
#=GS A0A1E4S8A0_CYBJN/79-244   AC A0A1E4S8A0.1
#=GS MPM1_YEAST/70-237         AC P40364.1
#=GS G8JVI1_ERECY/115-281      AC G8JVI1.1
#=GS G3B786_CANTC/110-292      AC G3B786.1
#=GS C5E1H0_ZYGRC/129-298      AC C5E1H0.1
#=GS A0A1G4JA84_9SACH/104-262  AC A0A1G4JA84.1
#=GS A0A421JIQ5_9ASCO/145-318  AC A0A421JIQ5.1
#=GS W0TCG8_KLUMD/70-216       AC W0TCG8.1
#=GS A0A1D2VJ33_9ASCO/18-181   AC A0A1D2VJ33.1
#=GS A0A1E4T309_9ASCO/130-258  AC A0A1E4T309.1
#=GS C4Y6N5_CLAL4/160-340      AC C4Y6N5.1
#=GS A0A1E3QL38_9ASCO/132-300  AC A0A1E3QL38.1
#=GS A5DF49_PICGU/128-327      AC A5DF49.2
#=GS A0A1E4TP15_PACTA/147-332  AC A0A1E4TP15.1
#=GS A0A1E4RGC7_9ASCO/140-303  AC A0A1E4RGC7.1
#=GS A0A1E3NKD1_9ASCO/261-392  AC A0A1E3NKD1.1
#=GS J4U4G9_SACK1/70-237       AC J4U4G9.1
#=GS A0A061AYL5_CYBFA/97-252   AC A0A061AYL5.1
#=GS A0A2P7YUL7_9ASCO/112-288  AC A0A2P7YUL7.1
#=GS H2AMK6_KAZAF/87-249       AC H2AMK6.1
#=GS M3J951_CANMX/129-299      AC M3J951.1
A0A1D8PSE0_CANAL/135-304             ..............h-GPSIRNYNECLTK.NGKSVWDDQGYWRCLFPNS...EVPVELLNFKKK..Y....LKDE.........................ILTKEDFMSA.MRK.NSaldnfqgdgmvdlkehGRFFDSYDKYLNWKNEQ.YNQRVKEREAK..WKQ.LSLNKGDNFATS........................---.-----.------....--..................--SSFSTSIKS.DMYT.DS.ETN.eVKFTKVKTeCDADGNCTVTRITKSKPV.......................
Q6BY44_DEBHA/158-338                 ...............KTPSIRHYHECIDK.KGESVWDSHGYWRCLFPNS...EVPNELLKLKNE..K....LGSE.........................ILTKEDFNNA.LTS.EQsserdg...vidlgekGIYFKQFTDFLNWKSIM.YENVKREKEKK..RQE.LIERRKQQAQEW........................---.KGYNA.PGGEM-....TN..................DKSVISSSVQS.SLSS.NM.DSN.eCVLNETRTeYYNDGTSCTKTITKSRPF.......................
A0A1X7R817_9SACH/99-279              ...............KTPSDTQFAQCMDS.QGLSVWDTNGWWRCLFPQN...IIRQNLPNLQET..-....ESAM.........................ILTKQKVEND.VNH.KF................GLYFTDYTKYLVWKSQM.NKIIKDKREKE..IEN.LKKPQLTKSADHkqdn................elvtMTP.ESLML.SDDSALs.tpEK..................DKLIIGTSEVL.RSSM.SS.EGL.tEETKELKT.YYDDGSIILKTEKKVTP-h......................
C5E373_LACTC/104-260                 ..............r-TPSDRQYLECQNI.KGLSVWDTHGWWRCLFPES...AVRSKVNAERLQ..-....---E.........................VLTREKVEKD.KNH.SL................GLFFTDYSAYLTWRANM.LRLADERRRSA..EES.ARDN--SWRPT-........................-TP.EDLMN.STPG--....--..................-KHVVGTSEYV.TYNT.TP.EGQ..EKVKETKT.YFNDGSVRLRSEKQRQ--gp.....................
A0A1E3NUS1_WICAA/97-252              ..............p-TPSATLYQKCMDK.DGLSVWDDKGWWRCLFPKL...ALDGE-------..-....---H.........................VLSKEDVLDD.KSN.KF................GLFFKDYTGYLDWKSQM.KQLVKQKDEEQ..KLA.RHRDNIESIYND........................-YS.KDSNF.EFGQG-....--..................GNDVISSSKSV.YFKT.LP.NGD.gEEVTEISN.VFRDGKSENKKFKRLIP-r......................
A0A1G4KH39_9SACH/113-281             ..............r-TPSDSQFMRCQDE.KGLSVWDTRGWWRCLLPAA...AMDSKLPGAKQL..-....--DS.........................VLTRERVESD.VHH.NL................GLFFTDYSRYLLWRSAL.LREAAERRKQQ..LAR.ADAARA--MRT-........................TTP.EDLMD.FGNATT....ARsg..............egANNVVGTSEYV.TYNS.TS.DGQ..EQVKETKT.FFADGSVRVRSETTK---sspe...................
A0A1E3NLF5_9ASCO/108-284             .............gi--PPPEIYEECTKA.EGLSLWDQQGLWHCLFPRS...KIPYDYGTGESH..A....FGVGpse...................akeLVSREDVEQD.TEN.KH................GLFFKNLEDMLGWQASM.KRAVAEQRRRQ..WSD.WEAKEKAKWNVW........................KSNsSSGGA.DGSSGD....DN..................GKEVVGRETET.RMVT.LD.NGD.fQRTTTQRR.VYSDGTSRIWEKTEV---vg.....................
A0A448YGK4_BRENA/101-289             ..............p-IPSVELYSNCKKM.NGLAAWDTHGYWHCLFPRA...NIPEEALSDPD-..-....----.........................TISREDVEAD.LDHkKY................GVFFENFNDLMDWKVKM.RDLMKEKKDKQ..WSQ.YREQEKAKWDFLnpgekke.........revenvrkD--.-----.---EPK....DSiydihsstssslpetdgvYRYASGTSSST.EVNT.LD.NGD.iEKTTCVRR.YYDDGSSEEREYKEI---ida....................
A0A2V1AT82_9ASCO/114-293             ..............r-SPSARKYNECMRK.DGESVWDSEGYWRCLFPNR...EIPNKLLNYKKS..H....LAGH.........................ILTKEDFDEA.IQE.KPdadkng...vidlgpkGMFFREFNRYLNWKNHM.YEDVRRQREES..RRN.LRESIRANTT-L........................-TP.---FS.RETEDR....ND..................DNGVVSYSMKT.YTKI.DS.EDD.kEVMHETRTeVFGDGRSVTKKSTRTRPI.......................
A0A1G4MF31_LACFM/104-258             ..............r-TPTNSQFEECQEV.KGLSVWDSHGLWRCLFPES...VVRTKVQPGQLS..-....---D.........................VVTREKVEND.NHH.NL................GLFFTEYSSYLTWRSHM.LRLAERRRKEA..RES.LETWRS------........................PTP.EDLTD.L-----....AT..................GKKVVGTSEYV.TYNT.TD.NGQ..EQIKETKT.YYDDGTVRLRSEKRH---tsp....................
Q758B0_ASHGO/115-286                 ...............KMPTDSQFMKCQEV.RGLSVWDTRGWWRCLFPKA...VVEKSLPAGQE-..-....--AG.........................VLTREQVEQD.REH.RH................GLFFPEYTGYLSWRSHM.LSLARQRREQE..EKN.RAARERKALPAVg......................tNAP.EDVMS.WTQQVAertpAS..................AANVVGTSKYT.TYSY.TD.RGH..EHITESKT.YYDDGTVAINSEKKITPV.......................
K0KQG7_WICCF/95-248                  ..............p-TPSAQLYQKCLDK.DGLSVWDDKGWWRCLFPKG...TLNGD-------..-....---R.........................VLSKEDVLED.KSN.KY................GLFFNDYTGFLGWKSQM.KQLIRQKDEEQ..KIS.RQRENIQDIYNG........................-YA.KDISF.ENGEH-....--..................--DIISSSKSV.SFRT.LP.NGD.gEEITEISN.YFKDGKSENKKFKRLIP-k......................
C5M3Z9_CANTT/132-304                 ...............KGPSIRYYNECLNK.DGKSVWDDQGYWRCLFPNS...EVPVELLNFKNK..Y....LSGD.........................ILTKEDFYNA.MKE.NTnsnvtg...tydlkdkGKFFDSYDNYLKWKNQQ.YQEQLEQRKKT..LAQ.RKEQLQQLSDSK........................---.-----.----GE....DF..................SKNIVSTSVKS.NTYT.DL.DTN.eVKYTQVKTeCDGEGNCIVTKITKSRPI.......................
G3AI36_SPAPN/155-332                 ...............KGPSMRQYHNCLEK.NGKSIWDDKGYWRCLFPNG...EIPVDMLNYKKK..Y....LYGE.........................ILTKEDFYDA.MKE.LSvnekep...tidlrekGTFFNKFDDYLNWKHVK.YSLKQVEQQRR..IAE.QQKLLEERKKQ-........................---.AELAP.KGQTV-....--..................DKRVVSTSVKS.HMYS.DS.ETN.eTKMIEEKVeCFNDGTCTTTKVTKSRPF.......................
M7NT83_PNEMU/114-232                 frehgvldrneretr--------------.-------------------...------------..-....----.........................----------.---.--................--DFERYRDFL-WRPRLfHDEIWKDAFET..FEE.LRTKEIDNEEVF........................ENK.NEYKKgKESSWD....ES..................SKKVTSTFSKK.MLRT.FG.DGS.yETIEIIKR.CFDDGTCETTKYTDS---sn.....................
A0A1E4T4V5_9ASCO/99-264              ..............p-TPSDKLYKSCKEK.EGLSAWDSKGYWRCLFPKA...LIPAEYAD----..-....---S.........................TLSKEDVQND.TNH.EK................GLFFENYTDYLDFKVKM.KEQLRIQREEE..WNK.FKEQQKSKWDFL........................ASK.NSDST.DNSTTS...fNDv................aGKKVTGTSSST.SIRT.LE.NGD.vEKNTILQQ.YFEDGSSERKSVKEI---lka....................
G8YBI5_PICSO/156-333                 ...............KNPPLRYYEECRNK.NGESVWDSYGYWRCLFPNA...EVPNEVLRKKNE..L....YGDA.........................VLTKEDFQEA.TKS.TPkfgddt...vidlgakGKFFTQFTDYLNWKSIM.KENVKRERLAR..QMK.DRELLSNGPSES........................---.-NGAV.VNDSG-....--..................ERRAVSSSVKS.SYNS.DS.ERN.eIIYNELRTeKYSDGTVSTKTITRTKPF.......................
G8BC20_CANPC/144-322                 ...............KGPSTRQYNDCLDK.HGKSLWDDRGYWRCLFPEA...EVPVDVLDFKKK..Y....FGDS.........................VVTKEDFFKY.MNE.LGanensr...aidlkekGTFFNTYEDYLVWRQDK.FSELKKKREEE..AKT.RAANRSKVLES-........................---.--LKQ.KQSEVA....DN..................DKYVTSTSIKS.NVFT.DL.DTN.eVKYIETKQeCFNDGNCVVTKIIKSKPI.......................
A0A1A0HH42_9ASCO/134-310             ..............q-GPTPKEFNTCMKK.EGVSLWDADGYWRCLFPNS...KIPANFLEYRKK..Q....LADE.........................IVTKEDFEEQ.ALL.APpnkdga....inlgpkGVFFRQFNDLLNWKNTK.YENEKKILDQQ..QQE.MRQNYQYNYSS-........................---.--FTK.GSDINN....EG..................EKTLVGTSSKS.TTNT.ES.SGE..IVSKETKTeYFSDGTSVTNSIVRRKP-q......................
A0A2H1A7P6_CANAR/115-293             ...............KSPSIRKYNECMRK.DGESVWDQEGYWRCLFPNS...QIPNKILNYKKN..H....LAGH.........................ILTKEDFSEA.LQE.NPgadqng...vidlgpkGIFFREFNRYLKWKNDM.YEDVRRQREES..RRN.LRESLKAQHQAE........................---.---SF.SSPTTG....GD..................GDNVVSWSMKT.VTET.DP.DTN.kEIMHETRTeVFEDGRSVTKKSTRSRPI.......................
G8ZT18_TORDC/131-294                 ..............r-TPTELQFTECNKV.GGLSVWNTKGWWRCLFPEK...EVSERLADQKDK..L....--QY.........................VLTKEKVEGD.SKH.KF................GLFFPEYTGFLTWKSHM.NQLIRERADKE..VAV.IQTEPK-----L........................STP.EDLMV.DTSKMN...dDR..................DKKVIGTSEYV.TYTY.TP.EGQ..KEVKKTKT.FYDNGTVLVRSENKLTPA.......................
A0A1G4KL30_9SACH/104-263             ..............r-TPSDKQFMECQEL.KGLSVWDSRGWWRCLFPES...VIGSKLAPEHM-..-....--ID.........................VLTREKVEND.KNH.RL................GLFFTEYTSYLTWRTNI.LRLAENRRNSL..AAK.AHDCDE-IQSIM........................ATP.EDLMD.RATG--....--..................-KSVVGTSEYV.TYNT.TP.EGL..EKIKEVKT.FYDDGSVKLRSEKQHR--ds.....................
A7TQM8_VANPO/115-287                 ...............KTPTESQFEKCQEI.GGLSVWNTKGWWRCLFPNA...VVQKNLDSLNIK.dN....IEDN.........................VLTREKVESD.KDHqKY................GLFFTDFSNYLQWRLHM.NRLIKEKEQQK..YET.DKLIKSDDFFST........................-TP.ENLMV.DEPSNFg..sTN..................GKTVVGQSKNV.SYSS.TL.EGK..ERLKEWKT.YYDDGSVSIKRETKIEPA.......................
Q6FPA9_CANGA/100-283                 ..............g-TPNMSQYKECADV.DGLSVWDTQGWWRCLFPQG...VIRDKLKVDDLS..S....KEQDsv....................mskILTKEAVVND.KDN.KY................GVFFPEWSLYMKWRVHM.NHLIQQRKEEE..ITK.RKNNDLKDWAYGfyd..................sddKTP.EDIMM.KKSLQDf.dhKD..................GPEIIGKSEYV.TIQS.TN.DGK..EEVKQLKT.FYNNGTTSIESIKKVYP-k......................
A0A367XZE6_9ASCO/138-310             ...............KGPSIRYYNECLDK.NGKSVWDDQGYWRCLFPNS...EVPVELLNFKNK..Y....LKGD.........................ILTKEDFYDA.MKE.NAksetpg...tvelkghGTFFDSYDAFLKWKSQQ.YQAQLEQRKKS..AEQ.RKQQLQKLSDTK........................---.-----.----GE....DF..................SKSIVSSSIKS.NTYT.DL.DTN.eVKYTQVKTeCDGEGNCIVTKITKLRPV.......................
A0A421JDK8_9ASCO/123-328             ..............q-APTSRYYHDCLQK.NGESVWDSEGYWRCLFPNA...EVPNSILAKKNS..-....--NQ.........................ILTKEDFNNA.AAH.ANvqdgv.....ydlgakGTYFKQFTDYLNWKEAM.YENVRREKENR..RNQ.LADQLADQPADQqwheqwhekhthcsphkrwhqrwhE--.-----.------....-KhqpqavetqekqvqkpeqDTGIVAYSVSN.VFNS.SN.EGN..-YLSETRTeRFKDGSTRTTTTTKRKPV.......................
A0A3F2XXM5_DEKBR/99-282              ..............p-VPSVELYSKCKKM.DGLEAWDSRGYWHCIFPXA...KIPEEVANDPEG..-....----.........................-YSKEDVEGD.FDHkKY................GIFFTNFNDLMDWQSKM.REVMKXKREKE..WSK.YRTQEKSKWDFLngdkpsd.........dnkvtgpfE--.-----.-TSD--....-Ntdvynvp...stepgdknFFRSTGTSSST.IVNT.LE.NGD.iEKTTSVKR.YFGDGTSEEREYKEI---id.....................
G0V7N4_NAUCC/71-236                  ..............g-VPDLKEYEQCKDL.QGLPVWDSHGWWQCLFPAT...VKPDQISKMGKV..-....--GG.........................YLTRDQVEND.KDH.KL................GLFFTEYTGYLDWKLKM.MKLVQQQREKE..EKT.KIETYDDWNKPL........................LTP.ENIMM.QDGQY-....-T..................KKKIVGKSEFVqSFNS.SD.EGK..GTVKNIKT.YYDDGSVLVRSEKRKTP-k......................
A0A1V2LIH9_PICKU/97-268              .............gi--PPPEVYDECKKA.EGLGVWDQYGLWHCLFPRS...SIPYDYHTGRRS..DdiiiDDSS.........................LVSREDIEND.VDH.KY................GTFFKNMEDMLGWQSSM.KRAIQEQKRRQ..WAD.WEKKEKSKWGFL........................--T.GFTNG.DDSSED....DE..................GKTVVGRESET.RVVT.LP.NGD.lERTTVMRR.RYSDGTSKVREFS-----eiig...................
A5DSA9_LODEL/161-359                 ...............KGPSIRQYHNCLDK.QGKSIWDEQGYWRCLFPES...EVPVRLLDYKKQ..H....LGDA.........................ILTKEDFFNH.MNQ.LGeneekp...vidlkeqGKWFNRFEDYLGWKRVA.YQEAQKKRELE..LKA.RQEAREKALLNL.......................rRND.SNGGA.DGGATT....TTtgggns.....pelaslqERYVTSSSIKS.NMFT.DP.ETN.eIKLIESKKeCFNDGNCLVTKITKLKPV.......................
I2H122_TETBL/83-281                  ...............KLPTDSQFEKCKKL.SGLSVWDTSGIWNCLFPKN...TPSDEINPPYTN..P....FKSNtsnnnegnsinksrfsthwepkllsAPNKEEVLAD.KKH.DL................GLFFSNYNVYLSWKLHM.KSLEKDLLETK..RKE.LIKQQNKQINFP........................NTP.EDIQI.FGSSSAtgndNK..................NKNIIGTSQSI.SMNS.TN.EGK..QKISLYKT.YFDDGTVSVKTETETTP-w......................
A0A0C7MXJ6_9SACH/104-263             ...............KTPSDKQYMNCKQL.DGLSVWDSRGWWRCLFPEK...VVGSNLNPDQMR..-....---T.........................VLTRERVEQD.KKH.NL................GLFFTEYSSYLSWRADV.LRLAETKRKSA..LAR.AERREELENI-S........................TTP.EDLMD.RATG--....--..................-RNVVGTSEYV.TYNN.TP.DGL..EKVKEVKT.FFDDGTVRLRSEKQRT--dp.....................
A0A1E3PTH5_9ASCO/166-358             ..............p-VPTSRQFYNCQQVyKGYSAWDCNGIWRCLFLKS...SSSADSLKDNMGdeA....KNQQ.........................HYFSEQLQRE.IAD.GGl..............kSVFFRTYNEFLNHNNDK.ILEHKRVEAEE..RNRfNKLIWAQPNGNS........................SNS.NDSSL.ATFSST....SLtnnslngkyitedqaksqGLTPVHSFYET.KVI-.GE.NGT.fMETKTIRK.IYSDGSQSVVET------atekr..................
A0A367Y8P4_9ASCO/138-310             ...............KGPSIRYYNECLDK.NGKSVWDDQGYWRCLFPNS...EVPVELLNFKNK..Y....LKGD.........................ILTKEDFYDA.MKE.NAksetpg...tvelkghGTFFDSYDAFLKWKSQQ.YQTQLEQRKKS..AEQ.RKQQLQKLSDTK........................---.-----.----GE....DF..................SKSIVSSSIKS.NTYT.DL.DTN.eVKYTQVKTeCDGEGNCIVTKITKLRPV.......................
A0A1E5RJJ9_HANUV/101-258             ..............r-TPTELQYMKCLEK.XGTIAWDTKGQFNCLFPQK...YLIERN------..-....LQDL.........................HLSKEQVDED.KDHkKY................GQFFYDYSKYLXWKFEN.KQXXXKENEVS..ILP.IKQDTDKYNQFE........................---.-SYSS.YTKQYV....DE..................EGNVQKEKVIE.NKYN.TP.EGL.kTKIERIK-.YPTDGSEPI---------seieekl................
A3LQV0_PICST/189-371                 ...............KTPSTRAYNNCLNK.AGESVWDSRGYWRCLFPNR...EVPVELLNYKQE..K....LRNT.........................ILTKEDLDNA.ILE.KGvdettsk.gvidlgekGVFFRKFDDYLSWKNIM.YANLRQQREEA..RKK.YLERVKTAKEVQ........................-SQ.AQPPV.ETDSN-....--..................ERRVVSNSYQS.FYTQ.NS.ETN.eVELKEIKTeSFNDGTSLTKTILKTRP-l......................
W6MJ79_9ASCO/141-312                 ..............p-TPSPELYRSCLEK.QGLSGWDERGYWRCLFPRG...IIPADAKG----..-....----.........................ILTKEDVEQG.LKE.--................GKFFPQVTDYLDWKGAM.KENMKEQRRER..WNR.KKREWAQYQEQE........................KKK.WDGVL.ASDNSK....SSglwakd......peanspRGDVTGSSSSY.SFRS.LP.DGS.tEKVSTTQQ.WFADGTSKVSEKKTVV--da.....................
A0A2T0FFF7_9ASCO/68-109              ..............r-VPSLYRYSQCKEN.NGVSAWTREGIWKCLMPSK...------------..-....----.........................----------.---.--................-----------------.-----------..---.------------........................---.-----.------....--..................-----------.----.--.---..--------.------------------deidfsdnk..............
A0A2T0FFF7_9ASCO/102-202             .......eidfsdnk--------------.-------------------...------------..-....----.........................----------.---.--................--LFRDYTGYLDFKLSM.YKAQQAQLEND..RRK.RHQSVM-----W........................RTP.KFISE.EE----....AQ..................GKNAVGERSFT.QTIT.DE.TGH..TETKRTLYkYFDDGTAFKKEET-----sag....................
J7SBT7_NAUDC/101-271                 ..............a-VPTLSQYEHCKNV.DGLSVWNRFGQWQCLFPAS...IKPDDIPLNAMG..Q....GKDP.........................YLTKEIVMGD.KDH.KL................GLYFTEFGDFLDWRLQM.SKLVQEKRLQE..QKK.SSPISSSSL---........................-TP.EGLML.DSYNDHgmndDK..................GKKVVGRAEFIqSFDS.TD.EGK..GTIKKFKT.YYDDGSVLIKSTKIKQPI.......................
C4R4B9_KOMPG/139-241                 ..............p-IPSHQLYKDCNSK.QGLSVWDEHGYWRCLFPKA...QLPENYKS----..-....IDSN.........................IISKEDVEQD.DSH.KL................GRFFTNFSDYLNWRSVM.EENIKKQRVSF..SKP.QKSSGS------........................---.-----.------....--..................-----------.----.--.---..--------.------------------stsyse.................
A0A1E4SJ09_9ASCO/146-323             ...............KSPSIRSYNDCMTK.NGESIWDSKGYWRCLFPNS...EVPVEYLRYKNE..N....FPER.........................ILTKEDFNSA.IKT.ASaqekdg...vidlgekGTYFRRLEDLMNWKSIM.YQNAREERANR..RRR.FHKQNQKLDE--........................---.--VAT.SQPATL....DT..................PKQVVSSSLQS.TYNM.NS.ESK.eVELNEIRTeYFSDGTLVTKTITKSKP-l......................
A0A1E3Q9H2_LIPST/286-331             ..............p-TPSAAQFKRCQLN.NGKGVWDTMGVWRCLLANS...S-----------..-....----.........................----------.---.--................-----------------.-----------..---.------------........................---.-----.------....--..................-----------.----.--.---..--------.------------------gkfdlgspsspr...........
A0A109UXJ7_9SACH/112-282             ..............t-MPTDEQFSRCKDL.KGLSVWDTKGWWRCLFPES...VVRRNIGTDEDL..-....--SK.........................ILTREKVEND.RSH.KF................GLFFPDYSGYLSWRSHM.LRLTKEKQQRE..QQE.RQKRENLLSSTP........................STP.EDLMA.WNHDSSvssaDA..................RGKVMGTSKYS.TFNS.TD.RGQ..EQIVESRT.YFEDGSVAIHSEKKIVP-y......................
G8BXJ8_TETPH/115-299                 ..............t-APTTEQYSSCMET.NGLSVWDSNGWWRCLFPRS...TIERNIEKKNLQ..N....SIYGeq....................knaILSKEDVLSD.VDHkKY................GIFFQEYTDLLNWKSQM.NRIIKNRQQEQntIAK.KNDELKSANSTDlv....................laDTP.ENLMM.TDYSSL....DDn...............idNKSVIGSAKYT.TYNS.TR.EGK..EKIQLWKT.YYDDDTVNIKSQKTIKPA.......................
Q6C365_YARLI/155-198                 ..............a-IPTKEMNDECADV.GGTGAWDVGGVWRCLFMKK...QDPQHSQNEK--..-....----.........................----------.---.--................-----------------.-----------..---.------------........................---.-----.------....--..................-----------.----.--.---..--------.------------------m......................
A0A0J9X913_GEOCN/106-259             ..............p-VPSTKQYQRCKDL.QGTSVWTRQGVWRCLFPQS...Q---NLLE----..-....----.........................----NELNKP.VSD.TG................RQIFGDYNAFLDWKVYM.RRLKEEKIEKQ..REE.LQRKWQENREKY........................AQA.VETTV.SKTGED....SP..................DKKVVSSSVST.HSYT.KD.DGT.fETKKTVKK.WYEDGTSSTVET------vsngp..................
Q6C365_YARLI/185-303                 ......mkkqdpqhs--------------.-------------------...------------..-....----.........................----------.---.QN................EKMFLKYDDFIDWRKQM.IDQIREKEVAS..DKE.RRDKLRAARSKW.......................eEDR.KSRMI.TEKEAK....DQ..................GLTVTRHSHQT.EMYY.DH.ASRewVKQDTIRK.FYNNGTES----------eivkesrdpi.............
W1Q9G8_OGAPD/111-264                 ..............p-IPSAKLYARCQEM.NGLSVWDANGAWRCLFPRA...SIPDDFGS----..-....----.........................ALAREDVEND.SSH.QK................GLFFQQYTDYLGFKVKM.TELANKKRKEE..WEK.FKEEQKSKWDFY........................---.-----.KDDKKW....GD..................SPNFTGSSTST.TIRT.LD.DGD.vEKVTVMKQ.FFSDGSSTIKETKEI---lns....................
A0A0J9X9F7_GEOCN/99-270              ..............p-VPSSVQDQRCRDL.GGKGVWTRESVWRCLFPTD...KRRLEYELEKS-..-....----.........................---------K.DGN.VE................GRLFGDYTSYLDWRAGM.KKATQYYTQQQ..QQK.YSSPTKAVNGYD........................NTW.KAQDE.KHQSYF....SNsalghtse..pnfdpsmnGENVISTISST.ETFK.KP.DGT.lGTKHIVKK.EYADGSKTTTER------iisnek.................
A0A1E5RZL8_9ASCO/171-264             ..............r-NPSDTQFAQCLSA.KGLGVWDPNGFWRCLFPKT...YIKEANLG----..-....--QN.........................ELSKEDVEQD.KEH.RL................GIFFKDYTGYLSWRNHM.MNIQSQSS---..---.------------........................---.-----.------....--..................-----------.----.--.---..--------.------------------salstdmaepn............
J7RHG3_KAZNA/74-158                  ..............p-VPTERQFAQCNDV.KGVSLWDKNGWWRCLFPQS...VVSGRLHGRP--..-....VPKG.........................TLTKEMWDRN.GGK.LD................G-FFNDYTTYMLWRVEQ.RKK--------..---.------------........................---.-----.------....--..................-----------.----.--.---..--------.------------------lsga...................
S6EPY0_ZYGB2/131-301                 ...............KTPTDSQFNECKDV.GGLSVWSTRGWWRCLFPEK...VVKDRLNDQKVL..-....--KG.........................IVTKEKVEAD.TGH.KL................GLFFPDYTGYLTWKAHM.NQLIREKKEKA..EQE.QQKQQALKLKEAds....................hlAIP.EDLMF.DTSGVT....DD..................VKQVISTYQNI.ISRA.TP.EGR..EQINERKT.YYDNGTVLLKTEKKLVP-a......................
G8YMD0_PICSO/156-333                 ...............KNPPLRYYEECRNK.NGESVWDSFGYWRCLFPNA...EVPNEILRKKNE..L....YGDA.........................VLTKEDFQEA.TRS.APdsddna...vidlgakGKFFRQFTDYLNWKSIM.KENVRRERLAR..QKK.DRELLSNSPVES........................---.-NGAV.VSDSG-....--..................ERRVVSSSVKS.SYNS.DS.ERN.eIIYNELRTeKYSDGTVSTKTITRTKPF.......................
Q6CLM4_KLULA/68-214                  ...............KTPSVEQFSKCNEL.KGVSVWDTRGLWRCLFPQS...VVQNG-------..-....----.........................GLSREAVEAD.KDH.KL................GLFFPEYSGFLSWRAHM.MALAKQKRKEE..REI.YS---------L........................STP.EDVML.NQVDSL....--..................GKNVVGTSSYS.TYKA.TP.EGK..ERIKEEKT.YYEDGTVLVKTKKKIYP-h......................
A0A1L0BAW6_9ASCO/127-301             ..............r-GPSTREYNDCLRK.DGTSVWDSEGYWRCLFPNS...EVPARLLDYKKS..H....LAGQ.........................ILTKEDFDDA.VQE.YPpkddgv....fdlgakGVFFKQYDQFLNWKNTM.YENVRKQREVS..RRR.IREAMISKE---........................---.-K-LF.DKLDS-....LD..................TPGVVSSSVLS.SMDS.NF.DTK.eVVLRETKTeVFSDGTSTTKYVTKTKPF.......................
A0A1E4S8A0_CYBJN/79-244              ..............p-TPSTTEYQQCKEG.DGVSAWDDKGWWRCLFPSK...SNYND-------..-....----.........................ELSYSDVSND.SEN.KH................GLFFKDYNSLMDWNLEM.RKLVKQKYDET..IRF.EKERENIQQIYD........................EHA.KDLDF.DLPAVE....KDntk...........vseyQNGYTSSSKSV.RIRT.LD.NGD.iEEITEIHQ.RFPDGSKEKKKFRKLIP-k......................
MPM1_YEAST/70-237                    ..............g-IPTVKQFDKCEEL.KGQSAWTTQGIWKCLVPSK...AIPPLPQL----..-....--DF.........................LLPLEEIKSD.KSH.SH................GLFFNDFNLFLKWRSHM.NRLQKQRIKTR..STA.VEPLARTPEDLM........................LNW.DDLHL.GNDAEYa.saDG..................SKKIVGRAQSI.STTK.DSnDAK.pSTVKTEKI.YFDDGTVDITTTTTSK--gs.....................
G8JVI1_ERECY/115-281                 ...............KTPTDTQFVQCKEV.DGLSVWDTKGWWRCLFPDA...IVRDRASATQGL..-....--SS.........................ILTKEMVQND.KQH.KY................GLFFSDYSGFLSWRSHM.IKLAKEKQQQK..EQQ.QRSLWPGS----........................STP.EDMLT.LADPENaltrDK..................KNKVVGSSSYT.TFNT.TE.NGH..EQITELKT.YYDDGSVSLKSEKNVFP-s......................
G3B786_CANTC/110-292                 ..............g-TPSIRKYNECIDK.KGQQLYDTHGHWRCLFPNA...EIPNKVLALRDS..R....FPGY.........................LLTKEEFQKE.VVT.RGinpdag...qydlgdqGMFFSQFEDYMNWKAIM.HRNIKEQRRQW..RNQ.LREEKKQLRKER........................EKS.RELQP.VGKDS-....DS..................SRRVVSSSTET.NYET.NT.NND..TVFKETKIqYFDDGTSLTTTITKSKPF.......................
C5E1H0_ZYGRC/129-298                 ..............r-TPTDGQFSQCKEL.GGLSVWNARGWWRCLFPEK...VVEERSEGELDL..-....--ER.........................VITREKVEAD.SKH.RL................GLFFPDFTGYLSWKAHM.NRLIKEKREKA..QKQ.QAVLEKESQASR.......................lSTP.EDLMF.DTSPTLg..gQD..................ERNVISRYQNV.MYKT.TP.EGR..EQINERKT.YYDNGTVLLKTEKKLTP-s......................
A0A1G4JA84_9SACH/104-262             ..............r-TPSDKQFMECHEL.KGLSVWDSRGWWRCLFPEN...IVRARMSPEQLK..-....---N.........................VLTRERVERD.KNH.SL................GLFFTEYSAYLMWRANI.VKQVEKRRASL..VPS.ASHEES-SQGLW........................NTP.EDLMD.HTTG--....--..................-KSVVGTSTYV.TYNS.TP.DGL..EKVKETKT.FFNDGSSKLRYDK-----qgtg...................
A0A421JIQ5_9ASCO/145-318             ...............KGPSMRQYHNCLEK.NGKSIWDDKGYWRCLFPNG...EVPIDMLNYKNK..Y....LTSE.........................ILTKEDFYDA.MNK.LNvnenea...ridlqekGSFFNKFEDYLNWKHVK.YSLQQQQKQQE..QQK.QLQEINKQSIES........................---.----V.-A---K....SS..................DKRVVSSSVKS.QMYS.DS.ETN.eTKMIEEKLeCFEDGTCLTSKIIKSRPF.......................
W0TCG8_KLUMD/70-216                  ..............r-MPTVEQFSKCNEL.NGLSVWDTRGLWRCLFPKS...VVKDN-------..-....----.........................GLSREAVESD.TEH.KK................GLFFPDYNGYLSWKSHM.VKLAMEKRKRE..RDL.YA---------L........................STP.EDVML.NQVDSL....--..................GKKVVGTSSYS.TYKA.TP.EGK..ERIKEEKT.FYEDGSVLVKTDKKIYP-h......................
A0A1D2VJ33_9ASCO/18-181              ..............p-IPSTNIYNVCKEK.SGLSVWDEKGVWRCLFPKA...IIPET-------..-....--EF.........................AVSKEDVLSNtYDN.NK................YKFFQDYTKYLDWRLHM.AEVDKQEREKR..RLE.AQTKFKEFYGLD........................KNS.NSSIE.KTDINKi..nES..................GKKVVGSSSSF.SSTT.KE.DGS.iENFTKIEK.WFEDGTSEIKETRKVIP-n......................
A0A1E4T309_9ASCO/130-258             ..............g-MPTLNECRLCDKW.KGVGVWNRNGEWVCVYQDA...MNGKESQLKKG-..-....-DIK.........................KFTKQFAFSE.SDE.LG................PKYFLKFSDYNAWKRSV.NLKIEQLEAKA..INC.CIFEDLKDVEDS.......................lKRI.EDLKR.VQSG--....--..................-----------.----.--.---..--------.------------------kidsefvvsvq............
C4Y6N5_CLAL4/160-340                 ..............g-QPSVREYNDCLRK.DGESLWDSNGYWRCLFPNK...EVPVALLDYKKA..H....LSNE.........................ILTKEDFTDA.AKE.SSgknvv......dlgpkGVFFKQFNDYLNWKNSE.YESVRKRREEA..IKK.ANEEREHWKQLH........................DSQ.SQSMT.TSGND-....SS..................KKAVVSLSVQT.SMDT.DT.DKN.eTVLREVRTqVFDDGTFTTTNITKSKPI.......................
A0A1E3QL38_9ASCO/132-300             ..............p-TPSSELYELCKEK.NGMAGWDHNGYWRCLFPKA...IIPPQFLLQKD-..-....----.........................LLTKEYAQSC.SST.SHngdiv.....yetpnnGKFFTGFSAYMDWSSAM.RKAQSAERLEK..LKE.KKKEWVSLLNEK........................-TS.-----.-EAPAL....EP..................AKEVTSTCTTT.SFYT.TK.DGT.eKNYTKIRQ.SFSDGTSQIKRVSKTK--ha.....................
A5DF49_PICGU/128-327                 ..............q-APSSRSYHECLQK.NGETVWDSEGYWRCLFPNA...EVPNSILAKKDS..-....--NQ.........................ILTKEDFNNA.AAH.ANvqdgv.....ydlgakGTYFKQFTDYLNWKEAM.YENVRREKENR..WNK.LKDSNQSWHESWhekhhk............rdfshkSLH.ERWHE.KHDSPQ....ESpeqve........ksepqDLGIVSYSVSN.VFNS.SN.EGN..-FLSETRTeRFKDGSTRTTTTTKRKPV.......................
A0A1E4TP15_PACTA/147-332             ..............p-SPSAETYEACKKK.DGLSVWNENGYWRCLFPRA...IIPPEKLN----..-....---S.........................TLTKEDVLED.KNN.EK................GLFFQDFNKYLDWKAHM.RRLQREEREEK..YKQ.LKNHCKEMKREMksrfrhrhhd...pendgslgsagS--.-----.------....-Tgstlekfn.dndndntfgSGKVVEVNSKF.HSYV.ND.NGK.kEEFSRYTK.VFKDGSSTTTEIKKT---fg.....................
A0A1E4RGC7_9ASCO/140-303             ..............g-APSARYYNECLNK.EGESVWDSKGYWRCLFPNR...EVPNELLNYKKQ..Y....KPDE.........................ILTKEDFEQA.VTE.KGasnedv....ielgnrGTFFKKFDAYLSWKNVM.YENVKREREMK..RQA.FKERQITNI---........................---.-----.------....-E..................DKQVVSSSIQS.SMNT.TD.DE-..IVLNEIKTeIFNDGSSITKNITKSKPV.......................
A0A1E3NKD1_9ASCO/261-392             ...............QTPTLLECQLCSKF.QGFMLWNRQHDWFCVYKDKlpsLIGNDATKITKA..Q....LDDE.........................NFRRNHVPQD.NDG.K-................-RYFTSFNDFIEWNTEY.TKKLIELERKA..YGA.KDMDEMTAVEAE........................---.-----.------....--..................-----------.----.--.---..--------.------------------iyelktlrkrrdkitadhivsvk
J4U4G9_SACK1/70-237                  ..............g-IPTVKQFDKCQEL.NGLSAWTAQGIWKCLVPGK...AISPLPKL----..-....--DF.........................LLPLEDVQSD.KSH.SR................GLFFNDFNLFLKWRSHM.NKLQQQRIKTR..STA.VNSAARTPEDLM........................LSW.DDLHL.GNDAEY....VSa...............ggSKNIIGRAQSI.STTKdSS.DAK.pCTVKTEKI.YFDDGTADVTTTTTSE--gs.....................
A0A061AYL5_CYBFA/97-252              ..............p-VPNTSQYEECQNK.KGLSVWDENGWWRCLFPRA...NLPQE-------..-....---G.........................GVSREDVEGD.RDN.KY................GVFFKEYNSLLDWKVQV.AKLVREKEEQK..RIQ.SETQTLNDIYAD........................-YE.KDLDW.DGVTG-....--..................QDGVVSTSKAV.HYKT.LP.NGD.aEEVTEIHN.TFRDGRSENKKFRKLIP-r......................
A0A2P7YUL7_9ASCO/112-288             ...............KSPSVRKYNECMRK.DGESVWDSEGYWRCLFPNR...EIPNKLLNYKKN..H....LSGH.........................ILTKEDFNEA.IQE.HPgadkng...vidlgpkGMFFREFNRYLNWKNHL.YEDVRRQREES..RRN.LRESMRAANPFT........................--P.-----.-ENEGQ....GQ..................PDEVVSYSTKI.YTNY.DR.DNN.nEVMHETKTeVMADGRSVTTKLTRTRPI.......................
H2AMK6_KAZAF/87-249                  ...............KGPTETQFANCLES.NGLSVWDTNGWWRCLFPDD...SVKKRLKMDNKT..L....HDAN.........................ILTREKIEND.YEH.KL................GLFFTDYTNYLLWKTNL.NKSVSDRKLEE..KAN.EF----NWNHTM........................TTP.EDLIF.NHSND-....--..................KKQVIGKSQFL.KFNS.TN.EGD..EEIKELKT.YYQDGTMSLKTQKKMTP-s......................
M3J951_CANMX/129-299                 ...............KGPSIRYYHECLDK.KGQSVWDEQGYWRCLFPNS...EVPIELLNFKNK..Y....LKGE.........................ILTKDDFTNA.MKD.NVqaakdg...vidlkdqGIFFNSYDKFLGWKHTQ.YEEQVEKRKQE..LKN.QLSKAKEH----........................---.-----.--SGDS....DF..................KRTVVSTSMTS.NRYT.DS.ETN.eVKLVKVKTeCDAEGNCIVTKTTKSKPI.......................
#=GC seq_cons                        ................sPoscpYpcChch.pGhSVWDspGaWRCLFPpu...tlssch.s.p...........tt.........................lLT+Echpps.hpc.ph................GhFFpcassYLsW+spM.hc.hccc+cpp..hpp.hppp.pp..t...............................t.....tst......tt..................tcpVluoS.ps.phpo.ss.-up..pphpch+p.hasDGos.hpp.pc.h.........................
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