#=GF ID   MSP1b
#=GF AC   PF03429.18
#=GF DE   Major surface protein 1B
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_4414 (release 6.6)
#=GF GA   25.00 25.00;
#=GF TC   27.60 26.90;
#=GF NC   22.70 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 81514348 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11239934
#=GF RT   Differential adhesion of major surface proteins 1a and 1b of the
#=GF RT   ehrlichial cattle pathogen Anaplasma marginale to bovine
#=GF RT   erythrocytes and tick cells. 
#=GF RA   de la Fuente J, Garcia-Garcia JC, Blouin EF, Kocan KM; 
#=GF RL   Int J Parasitol 2001;31:145-153.
#=GF DR   INTERPRO; IPR005091;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The major surface protein (MSP1) of the cattle pathogen
#=GF CC   Anaplasma is a heterodimer comprised of MSP1a and MSP1b.  This
#=GF CC   family is the MSP1b chain.  There MSP1 proteins are putative
#=GF CC   adhesins for bovine erythrocytes. 
#=GF SQ   15
#=GS B9KHR3_ANAMF/1-90           AC B9KHR3.1
#=GS B9KHM4_ANAMF/1-618          AC B9KHM4.1
#=GS A0A6A6JYN9_HEVBR/1050-1361  AC A0A6A6JYN9.1
#=GS B9KHL6_ANAMF/6-68           AC B9KHL6.1
#=GS A0A6A6K017_HEVBR/3-210      AC A0A6A6K017.1
#=GS A0A6A6JYL8_HEVBR/95-474     AC A0A6A6JYL8.1
#=GS A0A5P8VVI0_9NOSO/14-126     AC A0A5P8VVI0.1
#=GS B9KHL6_ANAMF/65-124         AC B9KHL6.1
#=GS B9KHL5_ANAMF/1-721          AC B9KHL5.1
#=GS A0A6A6JYL8_HEVBR/2-89       AC A0A6A6JYL8.1
#=GS B9KHR3_ANAMF/87-133         AC B9KHR3.1
#=GS B9KHR1_ANAMF/1-756          AC B9KHR1.1
#=GS A0A6A6JZQ8_HEVBR/259-387    AC A0A6A6JZQ8.1
#=GS A0A6A6JYN9_HEVBR/774-1073   AC A0A6A6JYN9.1
#=GS B9KHL6_ANAMF/121-390        AC B9KHL6.1
B9KHR3_ANAMF/1-90                      .......................................................MAEDDKQQQQNQSNVVQAISAVFQRKSAELQRLNDFIKGADGTLKNVHPHMKSLEALSKQLSEKIAAEA..AAKADAKYESVGLRAKAAA-----------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..-----------------------------------------------------------------------------------------...---...------------------...--------.-------------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------dy........................................................................................
B9KHM4_ANAMF/1-618                     .......................................................---------------------------------------------------------------------..---------------------------------------------------MDEAPDTGEKIEVPAGEEQEFGKAAAWGLAGFKRTVDESLEMLDRGMHMLAEGQAQISQGIDAKDTALVREGLETSRLGAGLCRNGLVEASYGVGYANE.TMGKYAGKGLDKCKNKLDNACHKWSKALEEIESLRTAIDAKAEQQVEGEAWSPEGVSANTFYKGLHKIGTAIAVAAQATWEGLAMTGKFMGAVAKLAGAVSMCVAA..YTAAIVGMAAATPATLLLTAMDNQS-VNNAVVKVSEYLHSNVEQATKDLMASEFAMMTFGGIMTCAKLMKGSFAAVNQKFEEINATLAR...EGT...DIAQGIKETY--------...---KSIGD.AFKSIGDAFKSVNTGIAKW.TTDKWTAALAGYASVEQLEEAKEADRVQAEQRAEAQAMTERVAGERAATVAAGTETIKTIVSDMRNELAKGHEQLQLVITDMCNELAQIGAFSQAERDALVKSFTPKPPARTTKELISHMHSGLESVMFRMARSLGIMSKASIEANSQDNSVEVAEISPET-QNMSD---AIPVEEAQIVETALLAAVNDTSKDDQAIVTDLINATIEVC.TEQTNTLAGHTAEVQAGLEAAGIKLDDAH----TTPEAKGVEGINQEELEQAAEGLAAAVNEASADGKMQFLKRE----------------------adlrreshqgk...............................................................................
A0A6A6JYN9_HEVBR/1050-1361             ....................steavysgikdavqklveqaktdhgaasdeylkhe---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..-----------------------------------------------------------------------------------------...---...------------------...----RVGEgVLKACEDAYNALKEAVTKAeNTLKAAAALPGQAY----DAIKQAAETRAQERADQAQVQQQISEAY--AMAMGGD-VKA-------ERTQQVNKAIDEATQIFAKLRDAGAISQEEMNQYVQSFAQQEPAKSARDLVDSVVSGISSVASRLAHGVVTIGQAIGEQVSQ----NVKDLLSST------------AADYKAVDEAMSKAANDN----NITAETLIGATVKACsTEQ----------AQQTKGAAGI---DQNTLQEA-QQTKGAAGIDQNTLQEAAEGLASAVNEV---GQISSLNQAETQIAQGQQ---QQSK------spvt......................................................................................
B9KHL6_ANAMF/6-68                      .............................................llnrslsdit---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..-----------------------------------------------------------------------------------------...---...------------------...--------.-------------------.---------------------------------------------------------------------------------------------------------------------------------------------------------------------------HESAETQIVETALLEAVNDSSKDDQAIVTDLINATIEVC.TEQTNTLAGHTAEV-----------------------------------------------------------------------------------..........................................................................................
A0A6A6K017_HEVBR/3-210                 .......................................mggdvkaertqqvnka---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..-----------------------------------------------------------------------------------------...---...------------------...--------.-------------------.---------------------------------------------------------------------------IDEATQIFTKLRDAGAISQEEMNQYVKSFAPQEPAKSAKDLVDSVVSGISSVASRLAHGVVTIGQAIGEQ-QVSQSVK-------------D-LLSAPAADCKAVDEAMSKAANDNN----VTAETLIGATVKACsTEQ----------AQQTKGAAGI---DQNTLQEA-QQTKGAAGIDQNTLQEAAAGLASAVNEA---GQISSLNQAETQIAQGQQ-----QQSGGWSR..........................................................................................
A0A6A6JYL8_HEVBR/95-474                ...........................................nsagqqsmasri---------------------------------------------------------------------..-----------------------------------------------------------------------------------QAHVDESVDMLSRGMHMVGEGQAKVAEGVEQKDVDLVKEGLELSGLGSSMCQKGLSYASWGIGEIRQgAMGAFASTGLEKCSKKLNEASLKWGNAVDEIKGLQTAINLGGTPTPSTEPWAPDGVGSNTFYAKLDSIAHKIAEAAKSTWEGLGMTGVFIGHVAKLAGTVSICTAF..MLGAVAGF----PVTTLMLTMDVDGKASELCEKFEKFIKDNIEQSARDIMASEFVSSVSGKLTTCAAAIKHAFAPVDALLDG----LST...QGL...ETDQAIVTAFKAVGDAIT...HC------.-------------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------gvlavsimkqgltkdtldmvlksteavysgikdavqklveqaktdhgaasdeylkhervgegvlkacedaynalkeavtkagnalkaaaa
A0A5P8VVI0_9NOSO/14-126                ............................................arydikgsfts---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..--------------------------------------------------------------------IKGSFTSIKDSSTSIKDSSTSikgSFTsikDSSTSIKDSFTSIKDSFTsikDSFTSIKD.SFTSIKDSFTSIKDSIRVL.QVKKCPIVIASEAFAERLEEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------qsq.......................................................................................
B9KHL6_ANAMF/65-124                    .......................................................---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..-----------------------------------------------------------------------------------------...---...------------------...--------.-------------------.-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAEVC.TKQTNTLAEHTAEVQAGLEAAGIRFDDAQGLQEATPEAKGVEGINPEELEQAAQ-------------------------------------------a.........................................................................................
B9KHL5_ANAMF/1-721                     .......................................................MAEDDKQQQQNQSNVVQAISAVFQRKSAELARLNAFVEGTDGTLKNIHPQMKSLEALSQQLSEKIAAEA..AAKADAKYESVGLRAKAAAALGSLGRLFRSGS-KGGYTPQD----IDALPFMDEAPDTGEKIEVPAGEEQEFGKAAAWGLAGFKRTVDESLEMLDRGMHMLAEGQAQISQGIADKSTALVREGLETSRLGAGLCRNGLVEASYGVSYANK.TMGKYAGKGLEKCKNKLDDACHKWHDALNEIESLRTAIDAKAEQQVEGEAWSPEGVSANTFYRGLHKIGAAIAVAAQATWEGLAMTGKFMGAVAKLAGAVSMCVAA..YTAAIAGV--ILPAGIPLAFMGPESKLAEYVDRAASYLHSNVEQATKDLMASEFAMMTFGGIMTCAKLMKGSFAAVNQKFEEINATLAR...EGT...DIAQGIKETY--------...--------.--KSIGDAFKSVNTGIAKW.TTDKWTAALAGYASVEQLEEAKEADRAQAEQRAEAQAMTERVAQERAATVAAGTETIKTIVS------------------DMCNELAQICGLSQAERDALVQSFIPQPP-RTTKEIVSQMCNSVKSAFGSISHITNVIRQAGKDAQKIDPQVKVAEISPETIYAMSEALYALNMQESAAINNALLEAVNDSSKDDQAIVTDLINATIEVC.TEQTNTLAGHTAEVQAGLEAAGIKLDDAH----TTPEAKGVEGINPEELAQAAEGLATAVNEASAEGKIQSLNQQESQIAQGGQHAAQQQSSSGWSR..........................................................................................
A0A6A6JYL8_HEVBR/2-89                  .....................................................pl--EDDKQQQ-----AVNAIKVAFANKFGELTKLSNFVRGADNRLSATKTHIDSLQELARQLSDKASAVGgvDNKYNQKTDAAGLGARA-------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..-----------------------------------------------------------------------------------------...---...------------------...--------.-------------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------ieqsm.....................................................................................
B9KHR3_ANAMF/87-133                    .......................................................---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.----------------------------------------------------------------------------------------------------------..---------------------------------AADYLHSNVEQATKDLMASEFAMMTFGGIMTCALLYIMSL----------------...---...------------------...--------.-------------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------gvlgaqq...................................................................................
B9KHR1_ANAMF/1-756                     .......................................................MTEDDKQQQQNQSDVVQAISAVFQRKSAELQRLNDFIKGADGTLKNVHPHMKSLEALSKQLSEKIAAEA..AAKADAKYESVGLRAKAAAALGNLGRLVARGKLKSSDAPKDLDQSIDALPFMDEAPDTGEKIEVPAGEEQEFGKAAAWGLAGFKRTVDESLEMLDRGMHMLAEGQAQISQGIDAKDTALVREGLETSRLGAGLCRNGLVEASYGVGYANE.TMGKYAGKGLDKCKNKLDNACHKWSKALEEIESLRTAIDAKAEQQVEGEAWSPEGVSANTFYKGLHKIGTAIAVAAQATWEGLAMTGKFMGAVAKLAGAVSMCVAA..YTAAIVGMAAATPATLLLTAMDNQS-VNNAVVKVSEYLHSNVEQATKDLMASEFAMMTFGGIMTCAKLMKGSFAAINQKFEEINATLTR...EAT...DIAQGVKETYQSIGDAFG...NAFKSVGD.AFKSIGDAFKSANDGIA--.---KWTAALAGYASVEQLEEAKEADRVQAEQRAEAQAMTERVAGERAATVAAGTETIKTIVSDMRNELAKGHEQLQLVITDMCNELAQIGAFSQAERDALVKSFTPKPPARTTKELISHMHSGLESVMFRMARSLGIMSKASIEANSQDNSVEVAEISPET-QNMSD---AIPVEEAQIVETALLAAVNDTSKDDQAIVTDLINATIEVC.TEQTNTLAGHTAEVQAGLEAAGIRFDDAQGLQEATPEAKGVEGINQEELEQAAEGLAAAVNEASADGKMQSLNQQETQIAQGEQ---QQQQSSGWSR..........................................................................................
A0A6A6JZQ8_HEVBR/259-387               .................................astfwgkfsilseamgnghims---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.---------------------LKWGDAVDEIKELQTAINRGGTPTPSTEPWAPDGVGSKNFYDKLDSIAHKIAEAAKSTWEGLGITGVFIGHVAKLAGTVSICTAHglQTAINRGVS--------------------------------------------------------------------------------...---...------------------...--------.-------------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------nvvdllynpde...............................................................................
A0A6A6JYN9_HEVBR/774-1073              sgifaiataadgkavliigvgdtaskvlgasdlvkaladlqgkgggntglarvsl---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.-----------ECSKKLNEASLKWGNAVDEIKGLQTAINRGGTPTPSTEPWAPDGVGSNTFYGKLDSIAHKIAEAAKSTWEGLGMTGVFIGHVAKLTGTVSLCAAF..MLGAVAGF----PVTTLMLTMDVDGKASELCEKFEKFIKDNIEQSARDIMASEFVSSVSGKLTTCAAAIKHAFAPVDALLDG----LST...QGL...ETDQAIVTAFKAVGDAIT...H-------.-------------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------cgvlavsimkqgltkdtldmvlksteavysgikdavqklveqaktdh...........................................
B9KHL6_ANAMF/121-390                   .......................................................---------------------------------------------------------------------..------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------------------AAQATWEGLAMTGKFMGAVAKLAGAVSMCVAA..YTAAIVGMAAATPATLLLTAMDNQS-VNNAVVKVSEYLHSNVEQATKDLMASEFAMMTFGGIMTCAKLMKGSFAAINQKFEEINATLTR...EAT...DIAQGVKETYQSIGDAFG...NAFKSVGD.AFKSIGDAFKSANDGIA--.---KWTAALAGYASVEQLEEAKEADRVQAEQRAEAQAMTERVAGERAATVAAGTETIKTIVSDMRNELAKGHEQLQLVITDMCNELAQIGAFSQAAYTA---------------------------------------------------------------------------------------------------------------.-------------------------------------------------------------------------------------------------alvglwct..................................................................................
#=GC seq_cons                          .........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................s.........................................................................................
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