GenomeNet

Database: Pfam
Entry: MotA_activ
LinkDB: MotA_activ
Original site: MotA_activ 
#=GF ID   MotA_activ
#=GF AC   PF09114.11
#=GF DE   Transcription factor MotA, activation domain
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1bja
#=GF GA   26.10 26.10;
#=GF TC   26.20 45.70;
#=GF NC   25.40 25.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9155025
#=GF RT   The activation domain of the MotA transcription factor from
#=GF RT   bacteriophage T4. 
#=GF RA   Finnin MS, Cicero MP, Davies C, Porter SJ, White SW, Kreuzer KN; 
#=GF RL   EMBO J. 1997;16:1992-2003.
#=GF DR   INTERPRO; IPR015198;
#=GF DR   SCOP; 1bja; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family of viral protein domains are implicated
#=GF CC   in transcriptional activation. They are almost completely
#=GF CC   alpha-helical, with five alpha-helices and a short,
#=GF CC   two-stranded, beta-ribbon. Four alpha helices (alpha1, alpha3,
#=GF CC   alpha4 and alpha5) are amphipathic and pack their hydrophobic
#=GF CC   surfaces around the central helix alpha2 [1].
#=GF SQ   38
#=GS I6YMQ6_9CAUD/4-100       AC I6YMQ6.1
#=GS A0A0A7HGA0_9CAUD/2-91    AC A0A0A7HGA0.1
#=GS A8R9P6_9CAUD/2-97        AC A8R9P6.1
#=GS A0A1B0VVJ6_9CAUD/2-97    AC A0A1B0VVJ6.1
#=GS A0A3T0IM25_9CAUD/2-97    AC A0A3T0IM25.1
#=GS A0A0B5A320_9CAUD/2-97    AC A0A0B5A320.1
#=GS Q7Y4P8_BPR69/2-97        AC Q7Y4P8.1
#=GS A0A0B6VSW4_9CAUD/2-97    AC A0A0B6VSW4.1
#=GS A0A2Z4QCP0_9CAUD/2-97    AC A0A2Z4QCP0.1
#=GS A0A1B1P9C8_9CAUD/2-97    AC A0A1B1P9C8.1
#=GS A0A2I6UFM1_9CAUD/2-97    AC A0A2I6UFM1.1
#=GS A0A0A0YQI8_9CAUD/2-97    AC A0A0A0YQI8.1
#=GS A0A240F466_9CAUD/4-98    AC A0A240F466.1
#=GS Q06E72_BPR32/2-96        AC Q06E72.1
#=GS J7KLW0_9CAUD/4-100       AC J7KLW0.1
#=GS A0A1Z1LYU5_9CAUD/2-97    AC A0A1Z1LYU5.1
#=GS A0A2Z5ZCE6_9CAUD/2-97    AC A0A2Z5ZCE6.1
#=GS E5DI00_9CAUD/2-97        AC E5DI00.1
#=GS MOTA_BPT4/2-96           AC P22915.1
#=GS MOTA_BPT4/2-96           DR PDB; 1BJA B; 2-96;
#=GS MOTA_BPT4/2-96           DR PDB; 1I1S A; 2-96;
#=GS MOTA_BPT4/2-96           DR PDB; 1BJA A; 2-96;
#=GS MOTA_BPT4/2-96           DR PDB; 6K4Y M; 3-96;
#=GS A0A2R3ZXE5_9CAUD/2-97    AC A0A2R3ZXE5.1
#=GS A0A0A0Q0Z1_9CAUD/2-97    AC A0A0A0Q0Z1.1
#=GS A0A2D1GMI5_9CAUD/2-97    AC A0A2D1GMI5.1
#=GS I7LHB8_9CAUD/12-107      AC I7LHB8.1
#=GS A0A023W6X3_9CAUD/1-95    AC A0A023W6X3.1
#=GS A0A159B7Z2_9CAUD/2-97    AC A0A159B7Z2.1
#=GS M1EAS7_9CAUD/2-97        AC M1EAS7.1
#=GS A0A249XX08_9CAUD/2-94    AC A0A249XX08.1
#=GS Q6U967_9CAUD/4-98        AC Q6U967.1
#=GS A0A2K9V620_9CAUD/2-97    AC A0A2K9V620.1
#=GS A0A2S1GM10_9CAUD/2-97    AC A0A2S1GM10.1
#=GS A0A2I6PF65_9CAUD/38-130  AC A0A2I6PF65.1
#=GS Q19CD8_9CAUD/4-100       AC Q19CD8.1
#=GS A0A0G2SSN1_9CAUD/2-94    AC A0A0G2SSN1.1
#=GS E5FJ40_9CAUD/2-91        AC E5FJ40.1
#=GS E3SF76_9CAUD/2-91        AC E3SF76.1
#=GS A0A0U3TFW4_9CAUD/2-97    AC A0A0U3TFW4.1
#=GS J7I561_9CAUD/4-100       AC J7I561.1
#=GS Q56EC9_9CAUD/4-98        AC Q56EC9.1
I6YMQ6_9CAUD/4-100                  tk--IEAIAKVlNNS.SISENATSVFIQVAKKAFITAAEIAE.A.T.EM.NKNA.-VYSNIGVMMKKGLIEKSGDGYVTTESGDAILIEAAEMWK---------aaqpeveapkv
A0A0A7HGA0_9CAUD/2-91               .n-KLNYIVKC.SQN.ALHETDVNALVFVYKNNFVSP----E.V.V.LD.QQNT.SIDS-VQTLLNNNYVEASGDGLMVTEKGVDLILDAAELWANENNPDLL-e..........
A8R9P6_9CAUD/2-97                   ..SKITYIIKA.SED.ALNEKTASILVHIIKHNFITSGEVRE.A.LsEQ.FSAA.VVNSNIGVLIKKGFIEKSGDGLVATGEAMDLVQKAADLFASENAPEML-e..........
A0A1B0VVJ6_9CAUD/2-97               ..SKVTYIIKA.SND.VLNEKTASILVKVAKQDFITSAELRE.Q.L.EDkMTAS.SVNSNIGVLIKKGLVEKSGDGLVITGEAQDIISNAAVLYAQENAPELL-e..........
A0A3T0IM25_9CAUD/2-97               ..SKITYIIKA.SED.VLNEKTASILVHIIKHNFITSGEVRE.A.LsEQ.FSAA.VVNSNIGVLIKKGFIEKSGDGLVATGEAMDLVQKAADLFASENAPEML-e..........
A0A0B5A320_9CAUD/2-97               ..SKLTYIVKA.SQD.VLNEKTASILMVILKTNFITSSEVRE.A.L.ADtLSAA.SVNSNIGVLIKKGLIEKSGDGFVSTGDATDIVQKAAVLFAEENNPELLK...........
Q7Y4P8_BPR69/2-97                   ..SKVTYIIKA.SEN.ALNEKTAAIMVYIIKNNFTTAANVRE.AlE.AE.YNAS.VVNSNIGVLIKKGLVEKSGDGLVATGEAMDIIQKAADLFAQENAPELL-q..........
A0A0B6VSW4_9CAUD/2-97               ..SKVTYIIKA.SND.TLNEKTAAILVHVIKNNFCTSADVRE.A.L.AE.TLNAsSVNSNIGVLLKKGLIEKSGDGLMATGEAMDIVQAAAVLHAEENKPELL-t..........
A0A2Z4QCP0_9CAUD/2-97               ..SKVTYIIKA.SEN.ALNEKTAAIMVYVIKNNFTTAANVRE.AlE.AE.YNAS.VVNSNIGVLIKKGLVEKSGDGLVATGEAMDIIQKAADLFAQENAPELL-q..........
A0A1B1P9C8_9CAUD/2-97               ..SKVTYIIKA.SED.ALNEKTAAILVQVAKKDFITSSELRE.I.L.EE.TMNAsSVNSNIGVLIKKGLIEKSGDGLIITGEAQDIISKAAVIYAEENKPELLK...........
A0A2I6UFM1_9CAUD/2-97               ..SKVTYIIKA.SND.VLNEKTASILIQVIKNNYITSAEIRD.L.L.SE.TMNAySVNSNIGVLLKKGLIEKSEDGLIATGEAMDIIQAAAVLHAEENKPELL-q..........
A0A0A0YQI8_9CAUD/2-97               ..SKVTYIIEA.SEN.VLNEKTAAILIKVAKGNFITSAELRE.E.L.VE.TMNAsSVNSNIGVLIKKGLIEKSGDGLVITGEAQDIISNAAVLYAQENAPELL-e..........
A0A240F466_9CAUD/4-98               tk--IEAIAKV.LNNaSISDNATQIFIQVAKKAFITVSEIAE.S.V.EM.NKNA.-VYSNIGVMIKKELIEKSGDGYITTEAGDAILVEAAEMWK---------aaqpveevk..
Q06E72_BPR32/2-96                   ..SKVTYIIKA.SND.VLNEKTAAILITIAKKDFITAAEVRE.V.H.PD.LGNA.VVNSNIGVLIKKGLVEKSGDGLIITGEAQDIISNAATLYAQENAPELLK...........
J7KLW0_9CAUD/4-100                  tk--IEAIAKVlNNS.SISENATSVFIQVAKKAFVTAAEIAA.A.T.-E.MNKN.AVYSNIGVMMKKGLIEKSGDGYVTTDCGDAILIEAAEMWK---------aaqpeveapkv
A0A1Z1LYU5_9CAUD/2-97               ..SKVTYIIKA.SND.VLNEKTASILIQVVKQNFITSSEIRE.N.L.AE.TMNAsSVNSNIGVLIKKGFIEKSADGFMVTEDGMDIINKAADIYAAEEKPELTK...........
A0A2Z5ZCE6_9CAUD/2-97               ..SKITYIIKA.SED.SLNEKTAAILTQVVKQNFITSAEIRE.N.L.AE.TINAsSVNSNIGVLIKKGFIEKSADGLMVTEDGMDIINKAADIYAAEEKPELTK...........
E5DI00_9CAUD/2-97                   ..SKVIYIVKA.SEN.SISENAANVLIVVAKKDFITSSEVRD.V.L.ADkLSAA.SVNSNIGVLIKKGLIEKSGDGLIVSAEGQEIINQAAVIYAEENAPELL-e..........
MOTA_BPT4/2-96                      ..SKVTYIIKA.SND.VLNEKTATILITIAKKDFITAAEVRE.V.H.PD.LGNA.VVNSNIGVLIKKGLVEKSGDGLIITGEAQDIISNAATLYAQENAPELLK...........
#=GR MOTA_BPT4/2-96           SS    ..XTHHHHHHH.TTT.SS-HHHHHHHHHHHHSTTB-HHHHHH.T.-.TT.S-HH.HHHHHHHHHHHTTSEEEETTEEEE-HHHHHHHHHHHHHHHHHTHCCHC-...........
A0A2R3ZXE5_9CAUD/2-97               ..SKVIYIVKA.SEN.SISENAANVLIAVAKKDFITSSEVRD.V.L.ADkLSAA.SVNSNIGVLIKKGLIEKSGDGLIVSAEGQEIINQAAVIYAEENAPELL-e..........
A0A0A0Q0Z1_9CAUD/2-97               ..SKVTYIIKA.SEN.ALNEKTAAILVHIVKNNFVTSAQVRE.A.L.VE.TLNAsSVNSNIGVLIKKGMIEKSGDGLIATGQAMDLIQKAADLFAAENAPEML-t..........
A0A2D1GMI5_9CAUD/2-97               ..SKVTYIIKA.SND.VLNEKTASILVKVAKQDFITSAELRE.Q.L.EDkMTAS.SVNSNIGVLIKKGLIEKSGDGLVITGEAQDIISNAAVLYAQENAPELL-e..........
I7LHB8_9CAUD/12-107                 ..SKLTYIVKA.SQD.VLNEKTASILMVILKTNFITSSEVRE.A.L.ADtLSAA.SVNSNIGVLIKKGLIEKSGDGFVSTGDAMDIVQKAAVLFAEENNPELLK...........
A0A023W6X3_9CAUD/1-95               .m-KLNYIISA.SAD.TLNEKTAAILIEVAKKNFITSAEIRE.T.L.TE.LNAS.SVNSNIGVLIKKNLIEKSGDGLIITEHGDEIVIKAAELHAADNKPELLK...........
A0A159B7Z2_9CAUD/2-97               ..SKVTYIIKA.SED.ALNEKTAAILVQVAKKDFITSSELRE.I.L.EE.TMNAsSVNSNIGVLIKKGLIEKSGDGLIITGEAQDIISKAAVIYAEENKPELLK...........
M1EAS7_9CAUD/2-97                   ..SKVTYIIKA.SND.VLNEKTASILVKVAKQDFITSAELRE.Q.L.EDkMTAS.SVNSNIGVLIKKGLIEKSGDGLVITGEAQDIISNAAVLYAQENAPELL-e..........
A0A249XX08_9CAUD/2-94               ..SKLSYVLKA.SSE.-LNEKTGAILLEVAKTNFIQAKDIRE.A.L.PE.ISSA.SINSNIGVLIKKGFIEKSGDGLIATEQGTEVILKAADIFAEENPS----kik........
Q6U967_9CAUD/4-98                   tk--IEAIAKV.LNNaSISDNATQIFIQVAKKAFITVSEIAE.S.V.EM.NKNA.-VYSNIGVMIKKELIEKSGDGYITTEAGDAILVEAAEMWK---------aaqpveevk..
A0A2K9V620_9CAUD/2-97               ..SKVTYIIKA.SED.ALNEKTAAILVQVAKKDFITSAELRE.I.L.EE.TMNAsSVNSNIGVLIKKGLIEKSGDGLIITGEAQDIISKAAVIYAEENKPELLK...........
A0A2S1GM10_9CAUD/2-97               ..SKVTYIIKA.SKD.SVSENAANVLIVIAKQNFISSAEVREkL.E.ET.LSAS.SVNSNIGVLIKKGLIEKSGEGLIITAEATDLLNEAARIYAEENKPELVK...........
A0A2I6PF65_9CAUD/38-130             ..SKLSYVLKA.-NS.ELNEKTGAILLVVAKTNFLQAKDIRE.A.L.PE.ISAA.SINSNIGVLIKKGFIEKSGDGLVTTEQGTEVVLKAADIYAEENPS----kik........
Q19CD8_9CAUD/4-100                  tk--IEAIAKVlNNS.SISENATSVFIQVAKKAFVTAVEIAA.V.T.EM.NKNA.-VYSNIGVLLKKGLIEKSGDGYVTTESGDTILIEAAEMWK---------aaqpeveapkv
A0A0G2SSN1_9CAUD/2-94               ..SKLSYVLKA.SSE.-LNEKTGAILLEVAKTNFIQAKDIRE.A.L.PE.ISSA.SINSNIGVLIKKGFIEKSGDGLIATEQGTEVILKAADIFAEENPS----kik........
E5FJ40_9CAUD/2-91                   .n-KLNYIVKC.SQN.ALHETDVNALVFVYKNNFVRP----E.V.V.LD.QQNT.SIDS-VQTLLNNNYVEASGDGLMITEKGVDLILDAAELWANENNPDLL-e..........
E3SF76_9CAUD/2-91                   .n-KLNYIVKC.SQN.ALHETVVNALVFVYKNNFVSP----E.V.V.LD.QQNT.SIDS-VQTLLNNNYVEASGDGLMITEKGVDLILDAAELWANENNPDLL-e..........
A0A0U3TFW4_9CAUD/2-97               ..SKVTYIIKA.SEN.ALNEKTAAIMVYIIKNNFTTAANVRE.AlE.AE.YNAS.VVNSNIGVLIKKGLVEKSGDGLVATGEAMDIIQKAADLFAQENAPELL-q..........
J7I561_9CAUD/4-100                  tk--IEAIAKVlNNS.SISENATSVFIQVAKKAFVTAVEIAE.A.T.EM.NKNA.-VYSNIGVMMKKGLIEKSGDGYVTTESGDAILIEAAEMWK---------aaqpeveapkv
Q56EC9_9CAUD/4-98                   tk--IEAIAKV.LNNaSISDNATQIFIQVAKKAFITVSEIAE.S.V.EM.NKNA.-VYSNIGVMIKKELIEKSGDGYITTEAGDAILVEAAEMWK---------aaqpveevk..
#=GC SS_cons                        ..XTHHHHHHH.TTT.SS-HHHHHHHHHHHHSTTB-HHHHHH.T.-.TT.S-HH.HHHHHHHHHHHTTSEEEETTEEEE-HHHHHHHHHHHHHHHHHTHCCHC-...........
#=GC seq_cons                       ..SKloYIlKA.Sps.sLNEKTAuILlpVAKpsFITuuElRE.s.l.t-.hpsA.SVNSNIGVLIKKGLIEKSGDGLlsTs-upDIIpcAAclaApENtPELL.t..........
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