GenomeNet

Database: Pfam
Entry: Myc-LZ
LinkDB: Myc-LZ
Original site: Myc-LZ 
#=GF ID   Myc-LZ
#=GF AC   PF02344.16
#=GF DE   Myc leucine zipper domain
#=GF AU   Bashton M;0000-0002-6847-1525
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_829 (release 5.2)
#=GF GA   22.70 22.70;
#=GF TC   22.90 22.80;
#=GF NC   22.50 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   10679391
#=GF RT   Action of Myc in vivo - proliferation and apoptosis. 
#=GF RA   Pelengaris S, Rudolph B, Littlewood T; 
#=GF RL   Curr Opin Genet Dev 2000;10:100-105.
#=GF RN   [2]
#=GF RM   9680483
#=GF RT   Insights into the mechanism of heterodimerization from the
#=GF RT   1H-NMR solution structure of the c-Myc-Max heterodimeric leucine
#=GF RT   zipper. 
#=GF RA   Lavigne P, Crump MP, Gagne SM, Hodges RS, Kay CM, Sykes BD; 
#=GF RL   J Mol Biol 1998;281:165-181.
#=GF DR   INTERPRO; IPR003327;
#=GF DR   SCOP; 1a93; fa;
#=GF DR   SCOP; 2a93; fa;
#=GF DR   PROSITE; PDOC00038;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   This family consists of the leucine zipper dimerisation domain
#=GF CC   found in both cellular c-Myc proto-oncogenes and viral v-Myc
#=GF CC   oncogenes.  Dimerisation via the leucine zipper motif with other
#=GF CC   basic helix-loop-helix-leucine zipper (b/HLH/lz) proteins such
#=GF CC   as  Max Swiss:P25912 is required for efficient DNA binding.  The
#=GF CC   Myc-Max dimer is a transactivating complex activating expression
#=GF CC   of growth related genes promoting cell proliferation. The
#=GF CC   dimerisation is facilitated via interdigitating leucine residues
#=GF CC    every 7th position of the alpha helix.  Like charge repulsion
#=GF CC   of  adjacent residues in this region perturbs the formation of
#=GF CC   homodimers  with heterodimers being promoted by opposing charge
#=GF CC   attractions.
#=GF SQ   235
#=GS A0A2K5RP63_CEBCA/407-437  AC A0A2K5RP63.1
#=GS A0A3B4BY67_PYGNA/405-435  AC A0A3B4BY67.1
#=GS F1RRR8_PIG/421-451        AC F1RRR8.4
#=GS A0A3B4VSA0_SERDU/360-390  AC A0A3B4VSA0.1
#=GS A0A1S3A6X8_ERIEU/406-435  AC A0A1S3A6X8.1
#=GS A0A3Q1F9B2_9TELE/395-425  AC A0A3Q1F9B2.1
#=GS A0A3Q1HH36_ANATE/349-377  AC A0A3Q1HH36.1
#=GS H0ZQJ1_TAEGU/399-429      AC H0ZQJ1.1
#=GS A0A096MB09_POEFO/297-327  AC A0A096MB09.1
#=GS W5MZP0_LEPOC/368-398      AC W5MZP0.1
#=GS A0A3B1J3E2_ASTMX/363-392  AC A0A3B1J3E2.1
#=GS U3J2T2_ANAPP/387-417      AC U3J2T2.2
#=GS MYC_FELCA/408-438         AC P68271.1
#=GS A0A3P9CR61_9CICH/374-404  AC A0A3P9CR61.1
#=GS I3M553_ICTTR/422-452      AC I3M553.2
#=GS A0A0D9RCK4_CHLSB/408-438  AC A0A0D9RCK4.1
#=GS A0A3Q1H7A1_ANATE/369-399  AC A0A3Q1H7A1.1
#=GS A0A452SGJ2_URSAM/408-438  AC A0A452SGJ2.1
#=GS F1PW15_CANLF/408-438      AC F1PW15.1
#=GS MYC_PANTR/408-438         AC P23583.1
#=GS H3DIC7_TETNG/386-416      AC H3DIC7.1
#=GS A0A286XIG5_CAVPO/407-437  AC A0A286XIG5.1
#=GS A0A1V4KVF0_PATFA/401-431  AC A0A1V4KVF0.1
#=GS A0A3Q3G9J9_9LABR/412-442  AC A0A3Q3G9J9.1
#=GS G1NRT5_MELGA/159-189      AC G1NRT5.1
#=GS A0A3Q2CR81_CYPVA/395-425  AC A0A3Q2CR81.1
#=GS A0A3Q1HEP0_ANATE/403-433  AC A0A3Q1HEP0.1
#=GS A0A3Q3GUA2_9LABR/352-380  AC A0A3Q3GUA2.1
#=GS MYC_SHEEP/408-438         AC Q28566.1
#=GS MYC_MOUSE/408-438         AC P01108.1
#=GS A0A384ANN3_BALAS/407-437  AC A0A384ANN3.1
#=GS A0A1I7Q473_MACMU/423-453  AC A0A1I7Q473.1
#=GS A0A3B4WWV0_SERLL/356-386  AC A0A3B4WWV0.1
#=GS A0A401S6A1_CHIPU/451-481  AC A0A401S6A1.1
#=GS A0A2K6PIE5_RHIRO/408-438  AC A0A2K6PIE5.1
#=GS G3LTW5_ORYLA/342-372      AC G3LTW5.1
#=GS A0A3Q0SU63_AMPCI/384-414  AC A0A3Q0SU63.1
#=GS A0A3Q3N4Y9_9TELE/362-392  AC A0A3Q3N4Y9.1
#=GS A0A2K6AZG2_MACNE/408-438  AC A0A2K6AZG2.1
#=GS A0A2K6TFG1_SAIBB/407-437  AC A0A2K6TFG1.1
#=GS A0A2U9CKH4_SCOMX/487-517  AC A0A2U9CKH4.1
#=GS A0A2K6EPJ0_PROCO/422-452  AC A0A2K6EPJ0.1
#=GS G3UBM1_LOXAF/410-439      AC G3UBM1.1
#=GS A0A060W7H8_ONCMY/441-467  AC A0A060W7H8.1
#=GS A0A452IPI6_9SAUR/441-471  AC A0A452IPI6.1
#=GS L9JL37_TUPCH/408-438      AC L9JL37.1
#=GS F6YAJ2_HORSE/413-442      AC F6YAJ2.2
#=GS H2TBQ9_TAKRU/385-415      AC H2TBQ9.2
#=GS A0A3P9AV56_9CICH/337-367  AC A0A3P9AV56.1
#=GS A0A3P8WWA5_CYNSE/405-435  AC A0A3P8WWA5.1
#=GS A0A3Q3AW73_KRYMA/356-386  AC A0A3Q3AW73.1
#=GS U3JIP7_FICAL/405-435      AC U3JIP7.1
#=GS A0A3B3B787_ORYME/396-426  AC A0A3B3B787.1
#=GS A0A3Q4GRP5_NEOBR/343-373  AC A0A3Q4GRP5.1
#=GS Q6NRN4_XENLA/390-420      AC Q6NRN4.1
#=GS A0A1D5Q496_MACMU/424-454  AC A0A1D5Q496.1
#=GS M3ZNV9_XIPMA/327-357      AC M3ZNV9.1
#=GS A0A3Q1H7Q6_ANATE/371-401  AC A0A3Q1H7Q6.1
#=GS A0A0P7V442_SCLFO/358-385  AC A0A0P7V442.1
#=GS G1T737_RABIT/409-439      AC G1T737.1
#=GS H0ZQJ0_TAEGU/401-431      AC H0ZQJ0.1
#=GS A0A3Q1B7F2_AMPOC/395-425  AC A0A3Q1B7F2.1
#=GS A0A3B4YIF4_SERLL/350-378  AC A0A3B4YIF4.1
#=GS A0A3P8NJ11_ASTCA/383-413  AC A0A3P8NJ11.1
#=GS A0A3Q3M208_9LABR/351-379  AC A0A3Q3M208.1
#=GS A0A2Y9LJB2_DELLE/408-438  AC A0A2Y9LJB2.1
#=GS A0A151P7W6_ALLMI/138-168  AC A0A151P7W6.1
#=GS MYC_RAT/408-438           AC P09416.1
#=GS D8LS55_ECTSI/20-49        AC D8LS55.1
#=GS A0A091FZ86_9AVES/222-252  AC A0A091FZ86.1
#=GS C0HB65_SALSA/352-380      AC C0HB65.1
#=GS A0A3Q2VJP5_HAPBU/338-368  AC A0A3Q2VJP5.1
#=GS A0A1U7TIM8_TARSY/311-341  AC A0A1U7TIM8.1
#=GS A0A3Q4MRJ7_NEOBR/74-104   AC A0A3Q4MRJ7.1
#=GS G1R0L9_NOMLE/423-453      AC G1R0L9.1
#=GS I3K8Y8_ORENI/389-418      AC I3K8Y8.1
#=GS F8WFG7_RAT/408-438        AC F8WFG7.2
#=GS MYCB_DANRE/367-396        AC Q7ZVS9.1
#=GS A0A3Q4MU02_NEOBR/328-356  AC A0A3Q4MU02.1
#=GS H0ZQJ2_TAEGU/387-415      AC H0ZQJ2.1
#=GS A0A3B3HIZ3_ORYLA/371-401  AC A0A3B3HIZ3.1
#=GS A0A2I3SFA1_PANTR/423-453  AC A0A2I3SFA1.1
#=GS MYC_PANPA/408-438         AC A1YG22.1
#=GS I3JFX0_ORENI/402-432      AC I3JFX0.1
#=GS A0A087WVR4_HUMAN/423-453  AC A0A087WVR4.1
#=GS F8WID3_MOUSE/423-453      AC F8WID3.1
#=GS A0A2U3ZRN8_ODORO/407-437  AC A0A2U3ZRN8.1
#=GS F7I481_CALJA/422-452      AC F7I481.1
#=GS A0A3B3TDE1_9TELE/424-454  AC A0A3B3TDE1.1
#=GS G1KK08_ANOCA/412-442      AC G1KK08.2
#=GS A0A2K5MUW0_CERAT/423-453  AC A0A2K5MUW0.1
#=GS A0A3Q3S045_9TELE/370-400  AC A0A3Q3S045.1
#=GS A0A494C098_HUMAN/422-452  AC A0A494C098.1
#=GS A0A3Q2VQ07_HAPBU/353-383  AC A0A3Q2VQ07.1
#=GS A0A3B4EVW8_9CICH/361-391  AC A0A3B4EVW8.1
#=GS A0A3Q2I924_HORSE/408-437  AC A0A3Q2I924.1
#=GS A0A2K5JM08_COLAP/423-453  AC A0A2K5JM08.1
#=GS A0A3B1J9P2_ASTMX/362-392  AC A0A3B1J9P2.1
#=GS A0A087WSQ0_MOUSE/422-452  AC A0A087WSQ0.1
#=GS A0A093GH59_DRYPU/246-276  AC A0A093GH59.1
#=GS A0A2K5X0Y9_MACFA/423-453  AC A0A2K5X0Y9.1
#=GS H3BYR3_TETNG/359-389      AC H3BYR3.1
#=GS A0A2K6TFF3_SAIBB/489-519  AC A0A2K6TFF3.1
#=GS I3J9K4_ORENI/331-359      AC I3J9K4.1
#=GS G3RS08_GORGO/423-453      AC G3RS08.1
#=GS A0A452EI51_CAPHI/408-438  AC A0A452EI51.1
#=GS A0A1L8FTT4_XENLA/161-190  AC A0A1L8FTT4.1
#=GS A0A3B1JCW1_ASTMX/345-374  AC A0A3B1JCW1.1
#=GS A0A087Y5Y0_POEFO/402-432  AC A0A087Y5Y0.2
#=GS A0A3P8SYT2_AMPPE/395-425  AC A0A3P8SYT2.1
#=GS A0A099ZEV6_TINGU/216-246  AC A0A099ZEV6.1
#=GS MYCA_DANRE/378-408        AC P52160.2
#=GS A0A3B4Z8C5_9TELE/343-371  AC A0A3B4Z8C5.1
#=GS A0A3Q2GX67_HORSE/368-397  AC A0A3Q2GX67.1
#=GS A0A3Q3C4V1_HAPBU/363-393  AC A0A3Q3C4V1.1
#=GS B2RSN1_MOUSE/423-453      AC B2RSN1.1
#=GS R0L9E7_ANAPL/354-384      AC R0L9E7.1
#=GS A0A3Q1GE53_9TELE/336-366  AC A0A3Q1GE53.1
#=GS C0H9V6_SALSA/355-383      AC C0H9V6.1
#=GS A0A3B3YKH8_9TELE/399-429  AC A0A3B3YKH8.1
#=GS A0A2Y9JAX5_ENHLU/408-438  AC A0A2Y9JAX5.1
#=GS A0A3P8S730_AMPPE/344-374  AC A0A3P8S730.1
#=GS A0A3Q7S0M0_VULVU/408-438  AC A0A3Q7S0M0.1
#=GS A0A2Y9QX77_TRIMA/407-437  AC A0A2Y9QX77.1
#=GS A0A2I4C604_9TELE/396-426  AC A0A2I4C604.1
#=GS MYC_CALJA/407-437         AC P49032.1
#=GS A0A401P8C1_SCYTO/439-469  AC A0A401P8C1.1
#=GS A0A3P9CQ97_9CICH/406-436  AC A0A3P9CQ97.1
#=GS A0A3Q2WS04_HAPBU/358-388  AC A0A3Q2WS04.1
#=GS W5U5R6_ICTPU/363-392      AC W5U5R6.1
#=GS A0A3M0KQK8_HIRRU/386-416  AC A0A3M0KQK8.1
#=GS A0A2K5CX16_AOTNA/432-462  AC A0A2K5CX16.1
#=GS M3ZII1_XIPMA/401-431      AC M3ZII1.1
#=GS A0A3Q3G5Z0_9LABR/449-479  AC A0A3Q3G5Z0.1
#=GS A0A3B4AJH1_9GOBI/370-400  AC A0A3B4AJH1.1
#=GS A0A3B4U1J8_SERDU/385-415  AC A0A3B4U1J8.1
#=GS A0A3B3HY75_ORYLA/425-455  AC A0A3B3HY75.1
#=GS A0A3B3HWZ7_ORYLA/496-526  AC A0A3B3HWZ7.1
#=GS H0WRX5_OTOGA/421-451      AC H0WRX5.1
#=GS A0A2K5CX06_AOTNA/407-437  AC A0A2K5CX06.1
#=GS A0A2K5CX21_AOTNA/418-448  AC A0A2K5CX21.1
#=GS A0A494C1T8_HUMAN/308-338  AC A0A494C1T8.1
#=GS A0A4D9EF12_9SAUR/377-407  AC A0A4D9EF12.1
#=GS M7BQH3_CHEMY/271-301      AC M7BQH3.1
#=GS A0A3P8QZL5_ASTCA/338-368  AC A0A3P8QZL5.1
#=GS A0A3P8XSJ1_ESOLU/376-406  AC A0A3P8XSJ1.1
#=GS A0A2U3XF43_LEPWE/407-437  AC A0A2U3XF43.1
#=GS A0A3B4D5H7_PYGNA/358-387  AC A0A3B4D5H7.1
#=GS A0A3Q3LZ53_9TELE/347-373  AC A0A3Q3LZ53.1
#=GS A0A1U7RVT0_ALLSI/207-237  AC A0A1U7RVT0.1
#=GS A0A3B3T8U2_9TELE/386-416  AC A0A3B3T8U2.1
#=GS A0A2U4B2V6_TURTR/408-438  AC A0A2U4B2V6.1
#=GS F6X065_MONDO/442-472      AC F6X065.2
#=GS A0A2K6AZF0_MACNE/423-453  AC A0A2K6AZF0.1
#=GS Q6P1T1_XENTR/387-416      AC Q6P1T1.1
#=GS A0A3Q1HUT1_ANATE/351-381  AC A0A3Q1HUT1.1
#=GS Q9DFB9_ICTPU/359-389      AC Q9DFB9.1
#=GS A0A2R8ZTP3_PANPA/423-453  AC A0A2R8ZTP3.1
#=GS A0A1S3NCS6_SALSA/410-440  AC A0A1S3NCS6.1
#=GS A0A060VPY2_ONCMY/363-393  AC A0A060VPY2.1
#=GS F7FXT9_ORNAN/151-181      AC F7FXT9.1
#=GS A0A3Q0T508_AMPCI/335-365  AC A0A3Q0T508.1
#=GS A0A3B4GZL3_9CICH/338-368  AC A0A3B4GZL3.1
#=GS W5PDV5_SHEEP/392-422      AC W5PDV5.1
#=GS K7FM32_PELSI/293-323      AC K7FM32.1
#=GS A0A3P9AB27_ESOLU/375-405  AC A0A3P9AB27.1
#=GS MYC_PIG/408-438           AC Q29031.1
#=GS A0A402F259_9SAUR/504-534  AC A0A402F259.1
#=GS F1RC36_DANRE/379-409      AC F1RC36.1
#=GS MYC_CHICK/385-415         AC P01109.1
#=GS L5K5M7_PTEAL/409-439      AC L5K5M7.1
#=GS A0A1S3FVS9_DIPOR/401-431  AC A0A1S3FVS9.1
#=GS A0A3Q2C645_CYPVA/333-361  AC A0A3Q2C645.1
#=GS G3NKK9_GASAC/368-398      AC G3NKK9.1
#=GS H3BC94_LATCH/382-412      AC H3BC94.1
#=GS H0YBT0_HUMAN/422-452      AC H0YBT0.1
#=GS A0A3Q3MII7_9TELE/364-394  AC A0A3Q3MII7.1
#=GS MYC_CANLF/408-438         AC Q28350.1
#=GS F1QDI6_DANRE/331-360      AC F1QDI6.1
#=GS A0A3L8T3N9_CHLGU/387-417  AC A0A3L8T3N9.1
#=GS A0A3Q2ZA23_KRYMA/340-370  AC A0A3Q2ZA23.1
#=GS W5MZP7_LEPOC/368-398      AC W5MZP7.1
#=GS A0A2K6MCC6_RHIBE/423-453  AC A0A2K6MCC6.1
#=GS G3SNI5_LOXAF/411-440      AC G3SNI5.1
#=GS A0A2K5YPL3_MANLE/423-453  AC A0A2K5YPL3.1
#=GS A0A340X7X5_LIPVE/409-439  AC A0A340X7X5.1
#=GS A0A3B3U9Y0_9TELE/399-429  AC A0A3B3U9Y0.1
#=GS A0A3P9NAH7_POERE/415-445  AC A0A3P9NAH7.1
#=GS A0A384BZF2_URSMA/231-261  AC A0A384BZF2.1
#=GS A0A452IP49_9SAUR/377-407  AC A0A452IP49.1
#=GS H2PR71_PONAB/422-452      AC H2PR71.2
#=GS A0A3B3X6D2_9TELE/394-424  AC A0A3B3X6D2.1
#=GS G9KC04_MUSPF/422-452      AC G9KC04.1
#=GS A0A3Q7WL24_URSAR/408-438  AC A0A3Q7WL24.1
#=GS A0A3P8YS79_ESOLU/356-384  AC A0A3P8YS79.1
#=GS A0A1D5R6Y1_MACMU/423-453  AC A0A1D5R6Y1.1
#=GS A0A3Q3W929_MOLML/381-411  AC A0A3Q3W929.1
#=GS A0A096N777_PAPAN/408-438  AC A0A096N777.1
#=GS A0A060W9P8_ONCMY/340-367  AC A0A060W9P8.1
#=GS A0A3Q3WKH5_MOLML/343-371  AC A0A3Q3WKH5.1
#=GS A0A3P9NIJ9_POERE/391-421  AC A0A3P9NIJ9.1
#=GS A0A3B3XDM1_9TELE/352-382  AC A0A3B3XDM1.1
#=GS A0A0Q3Q8U6_AMAAE/385-415  AC A0A0Q3Q8U6.1
#=GS G5B9M9_HETGA/361-391      AC G5B9M9.1
#=GS A0A3B5BGJ5_9TELE/407-437  AC A0A3B5BGJ5.1
#=GS A0A1S3LUE5_SALSA/369-399  AC A0A1S3LUE5.1
#=GS G1KL38_ANOCA/449-478      AC G1KL38.2
#=GS A0A3B4Z6W3_SERLL/385-415  AC A0A3B4Z6W3.1
#=GS H3BC93_LATCH/362-391      AC H3BC93.1
#=GS A0A3Q2VQL6_HAPBU/381-411  AC A0A3Q2VQL6.1
#=GS MYC_BOVIN/408-438         AC Q2HJ27.1
#=GS A0A3B3E2T5_ORYME/342-372  AC A0A3B3E2T5.1
#=GS G1M831_AILME/421-451      AC G1M831.1
#=GS G1QCG9_MYOLU/409-439      AC G1QCG9.1
#=GS A0A3B4TAF5_SERDU/350-378  AC A0A3B4TAF5.1
#=GS A0A1U7QQI6_MESAU/409-439  AC A0A1U7QQI6.1
#=GS A0A2I4CR04_9TELE/322-350  AC A0A2I4CR04.1
#=GS A0A3B4B130_9GOBI/332-361  AC A0A3B4B130.1
#=GS A0A087WUS5_HUMAN/423-453  AC A0A087WUS5.1
#=GS A0A402E7S5_9SAUR/169-199  AC A0A402E7S5.1
#=GS A0A3Q1CVI3_AMPOC/346-376  AC A0A3Q1CVI3.1
#=GS A0A3B5B9W9_9TELE/391-421  AC A0A3B5B9W9.1
#=GS H2QWQ2_PANTR/408-438      AC H2QWQ2.2
#=GS A0A2K5MVB9_CERAT/408-438  AC A0A2K5MVB9.1
#=GS A0A0P7V0S8_SCLFO/160-190  AC A0A0P7V0S8.1
#=GS A0A2Y9EJZ9_PHYMC/408-438  AC A0A2Y9EJZ9.1
#=GS A0A3Q2UD68_CHICK/398-428  AC A0A3Q2UD68.1
#=GS MYC_MACMU/408-438         AC B8XIA5.1
#=GS A0A3B4ZYU3_9TELE/340-370  AC A0A3B4ZYU3.1
#=GS MYC_HUMAN/408-438         AC P01106.1
#=GS MYC_HUMAN/408-438         DR PDB; 1NKP D; 555-581;
#=GS MYC_HUMAN/408-438         DR PDB; 5I50 B; 61-91;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6L C; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6K A; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 1NKP A; 955-981;
#=GS MYC_HUMAN/408-438         DR PDB; 2OR9 P; 1-10;
#=GS MYC_HUMAN/408-438         DR PDB; 1A93 A; 8-34;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6J A; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6K C; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 2A93 A; 8-34;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6J C; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 5I50 A; 61-91;
#=GS MYC_HUMAN/408-438         DR PDB; 5I4Z B; 61-91;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6L A; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6L G; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 6G6L E; 955-984;
#=GS MYC_HUMAN/408-438         DR PDB; 5I4Z A; 61-91;
#=GS A0A1S3QA70_SALSA/367-397  AC A0A1S3QA70.1
#=GS A0A087Y5W6_POEFO/401-431  AC A0A087Y5W6.2
#=GS F6PX41_MOUSE/422-452      AC F6PX41.1
#=GS A0A060WAZ1_ONCMY/370-400  AC A0A060WAZ1.1
#=GS A0A060W4A2_ONCMY/377-405  AC A0A060W4A2.1
A0A2K5RP63_CEBCA/407-437             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3B4BY67_PYGNA/405-435             ...SDEQRLLSVKEQLRRKSELLKHRLQQLRRSQ..
F1RRR8_PIG/421-451                   ...AEEQKLVSEKDVLRKRREQLKLKLEQLRNSC..
A0A3B4VSA0_SERDU/360-390             ...EDERRLLTMKDELRKRSRELKLRLEQLRT--lh
A0A1S3A6X8_ERIEU/406-435             ...TEEQKLLSEKDLLRKRREHLKHRLEQLRNC-..
A0A3Q1F9B2_9TELE/395-425             ...TDEQRLLSLKEQLRRKSELLKQRLAQLQSSR..
A0A3Q1HH36_ANATE/349-377             ..n-EGHRLKTKKDKLRAKQEELKARLAQLRS--..
H0ZQJ1_TAEGU/399-429                 ...SEEHRLIAEKEQLRRRREQLKHKLEQLRNCC..
A0A096MB09_POEFO/297-327             ...ADERRLLKKKDELTKRSRELQRRLERLRT--lh
W5MZP0_LEPOC/368-398                 ...ADEQRLISLKEQLRRKSEQLKHRLAQLRS--ph
A0A3B1J3E2_ASTMX/363-392             ...AEERRLLSVKEQLRRRCEHLKHRLEQLSNS-..
U3J2T2_ANAPP/387-417                 ...SDEHRLIAEKELLRRRREQLKHKLEQLRNSR..
MYC_FELCA/408-438                    ..a-GEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3P9CR61_9CICH/374-404             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
I3M553_ICTTR/422-452                 ...AEEQKLISEKDLLRKRREQLKQKLEQLRNSC..
A0A0D9RCK4_CHLSB/408-438             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3Q1H7A1_ANATE/369-399             ...SDEQRLLSLKEQLRRKHELLKQRLALLQSSR..
A0A452SGJ2_URSAM/408-438             ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
F1PW15_CANLF/408-438                 ...AEEQKLLSEKDLLRKRREQLKHKLEQLRNS-g.
MYC_PANTR/408-438                    ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
H3DIC7_TETNG/386-416                 ...SDEQRLLQLKEQLSRKSELLKQRLAQLHGSR..
A0A286XIG5_CAVPO/407-437             ...AEEQKLLSDKDLLRKRREQLKHKLDQLRNSC..
A0A1V4KVF0_PATFA/401-431             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSC..
A0A3Q3G9J9_9LABR/412-442             ...SDEQRLLSVKEQLRRRSELLKQKLSQLQG--ar
G1NRT5_MELGA/159-189                 ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSR..
A0A3Q2CR81_CYPVA/395-425             ...SDEQRLLSLKEQLRRKSELLKQRLAQLQGSR..
A0A3Q1HEP0_ANATE/403-433             ...SDEQRLLSLKEQLRRKHELLKQRLALLQSSR..
A0A3Q3GUA2_9LABR/352-380             .eh--ERRLLTTKEELRRRSRELRHRLKQLRT--..
MYC_SHEEP/408-438                    ...AEEQKLISEKDVLRKRREQLKLKLEQIRNSC..
MYC_MOUSE/408-438                    ...ADEHKLTSEKDLLRKRREQLKHKLEQLRNS-g.
A0A384ANN3_BALAS/407-437             ...AEEQKLISEKDELRKRREQLKLKLEQLRNSC..
A0A1I7Q473_MACMU/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3B4WWV0_SERLL/356-386             ...EDERRLLTMKDELRKRSRELKLRLEQLRT--lh
A0A401S6A1_CHIPU/451-481             ...SNEQRLILEKEQLRRKQEQLKHRLEQLRNS-s.
A0A2K6PIE5_RHIRO/408-438             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
G3LTW5_ORYLA/342-372                 ..g-DERKLLTTKEELRKRSRELKRRLEQLRT--lh
A0A3Q0SU63_AMPCI/384-414             ...SDEQRLLSLKEQLRRRSELLKQRLAQLQSCR..
A0A3Q3N4Y9_9TELE/362-392             ...EDERRLLKMKDELRKRSRELKHRLERLRTSH..
A0A2K6AZG2_MACNE/408-438             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A2K6TFG1_SAIBB/407-437             ...AEEQKLISEKDLLRKRRDQLKHKLEQLRNSC..
A0A2U9CKH4_SCOMX/487-517             ...SDEQRLLSLKEQLRRKSELLKQRLAQLHGSC..
A0A2K6EPJ0_PROCO/422-452             ...AEEQKLISEKDSLRKRREQLKHKLEQLRNSC..
G3UBM1_LOXAF/410-439                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNS-..
A0A060W7H8_ONCMY/441-467             ...TDEQKLLLLKEQLRKKSEQL----EQLRNSQ..
A0A452IPI6_9SAUR/441-471             ...TDEHRLITEKEQLRKRREQLKHKLEQLRNSC..
L9JL37_TUPCH/408-438                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
F6YAJ2_HORSE/413-442                 ...AEEQKLVSEKDLLRKRREHLQLKLEQLRNC-..
H2TBQ9_TAKRU/385-415                 ...SDEQRLLLLKEQLNRKSELLKQRLAQLQGSR..
A0A3P9AV56_9CICH/337-367             .eq--ERKLLAKKDELRKRSRELKQRLQQLRTSH..
A0A3P8WWA5_CYNSE/405-435             ...SDEQKLISLKEQLRRRSELLKQRLAQLQGSR..
A0A3Q3AW73_KRYMA/356-386             ...SDEQRLVSLKEQLRRRSELLRQRLAQLQGCR..
U3JIP7_FICAL/405-435                 ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNCC..
A0A3B3B787_ORYME/396-426             ...SDEQRLISFKEQLRRKSELLKQRLAQLQASR..
A0A3Q4GRP5_NEOBR/343-373             .eq--ERKLLAKKDELRKRSRELKQRLQQLRTSH..
Q6NRN4_XENLA/390-420                 ...EDERRLIRETEQLKYRKEQLKQRLQQLRNS-v.
A0A1D5Q496_MACMU/424-454             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
M3ZNV9_XIPMA/327-357                 ...ADERRLLKKKDELTKRSRELQRRLERLRT--lh
A0A3Q1H7Q6_ANATE/371-401             ...SDEQRLLSLKEQLRRKHELLKQRLALLQSSR..
A0A0P7V442_SCLFO/358-385             ..m-ESQRLSAKKDKLRQRQEQLKLRLEQLR---..
G1T737_RABIT/409-439                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
H0ZQJ0_TAEGU/401-431                 ...SEEHRLIAEKEQLRRRREQLKHKLEQLRNCC..
A0A3Q1B7F2_AMPOC/395-425             ...TDEQRLLSLKEQLRRKSELLKQRLAQLQSSR..
A0A3B4YIF4_SERLL/350-378             ..d-EGHRLQTKRDRLKARQEELKARLEQLHS--..
A0A3P8NJ11_ASTCA/383-413             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
A0A3Q3M208_9LABR/351-379             ..d-EGHRLQSKRDRLRAKQEELKARLEQLRS--..
A0A2Y9LJB2_DELLE/408-438             ...AEEQKLISEKDELRKRREQLKLKLEQLRNSC..
A0A151P7W6_ALLMI/138-168             ...TDEHRLIAEKEQLRRRRDQLKHKLEQLRNSC..
MYC_RAT/408-438                      ...ADEHKLISEKDLLRKRREQLKHKLEQLRNS-g.
D8LS55_ECTSI/20-49                   ...ADEKKHSAEVDQLKRTNEQLKTTLEQMLS--a.
A0A091FZ86_9AVES/222-252             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSC..
C0HB65_SALSA/352-380                 ..g---QRLNVKRDKLRERQEQLKVKLEQLRR--qr
A0A3Q2VJP5_HAPBU/338-368             .eq--ERKLLAKKDELRKRSRELKQRLQQLRTSH..
A0A1U7TIM8_TARSY/311-341             ...AEEQKLVAEKGLLRQRREHLKHRLEQLRNSC..
A0A3Q4MRJ7_NEOBR/74-104              ...TDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
G1R0L9_NOMLE/423-453                 ..g-EEQKLTSEKDLLRKRREQLKHKLEQLRNSC..
I3K8Y8_ORENI/389-418                 .eq--ERKLLAKKDELRKRSRELKQRLQQLRTS-..
F8WFG7_RAT/408-438                   ...ADEHKLISEKDLLRKRREQLKHKLEQLRNS-g.
MYCB_DANRE/367-396                   ...EDEQRLISLKEQLRRKCEHLKQRLEQLSCS-..
A0A3Q4MU02_NEOBR/328-356             ..d-ESHRLQTRKDKLKAKQEQLKARLEQLRR--..
H0ZQJ2_TAEGU/387-415                 ...SEEHRLIAEKEQLRRRREQLKHKLEQLRN--..
A0A3B3HIZ3_ORYLA/371-401             ...SDEQRLISFKEQLRRKSELLKQRLAQLQGSR..
A0A2I3SFA1_PANTR/423-453             ...AEEQKLISEEDLLRKRREQLKHKLEQLQNSC..
MYC_PANPA/408-438                    ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
I3JFX0_ORENI/402-432                 ...SDEQKLLSLKEQLRRRSEQLKQRLAHLQGCR..
A0A087WVR4_HUMAN/423-453             ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
F8WID3_MOUSE/423-453                 ...ADEHKLTSEKDLLRKRREQLKHKLEQLRNS-g.
A0A2U3ZRN8_ODORO/407-437             ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
F7I481_CALJA/422-452                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3B3TDE1_9TELE/424-454             ...TDEQRLLSLKEQLSRRSQHLKQRLERLRNC-q.
G1KK08_ANOCA/412-442                 ...EDEHKLLAEKEQLRRRQEQLKNKLQQLRNSC..
A0A2K5MUW0_CERAT/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3Q3S045_9TELE/370-400             ...SDEQNLVSLKEQLKMKSELLKQRLAQLQRS-l.
A0A494C098_HUMAN/422-452             ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
A0A3Q2VQ07_HAPBU/353-383             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
A0A3B4EVW8_9CICH/361-391             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
A0A3Q2I924_HORSE/408-437             ...AEEQKLVSEKDLLRKRREHLQLKLEQLRNC-..
A0A2K5JM08_COLAP/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3B1J9P2_ASTMX/362-392             ...SDEQKLLSIKEQLRRKSEQLKHRLQLLRRSQ..
A0A087WSQ0_MOUSE/422-452             ...ADEHKLTSEKDLLRKRREQLKHKLEQLRNS-g.
A0A093GH59_DRYPU/246-276             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSC..
A0A2K5X0Y9_MACFA/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
H3BYR3_TETNG/359-389                 ...SDEQRLLQLKEQLSRKSELLKQRLAQLHGSR..
A0A2K6TFF3_SAIBB/489-519             ...AEEQKLISEKDLLRKRRDQLKHKLEQLRNSC..
I3J9K4_ORENI/331-359                 ..d-ESHRLQTRKDKLKAKQEQLKARLEQLRR--..
G3RS08_GORGO/423-453                 ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
A0A452EI51_CAPHI/408-438             ...AEEQKLISEKDVLRKRREQLKLKLEQIRNSC..
A0A1L8FTT4_XENLA/161-190             ...EDERRLIRETEQLKYRKEQLKQRLQQLRN--f.
A0A3B1JCW1_ASTMX/345-374             ...TEEQRLSHKKDKLRQRQEQLRVRLEQLRR--l.
A0A087Y5Y0_POEFO/402-432             ...SDEQRLVSLKEQLRRKSELLKQRLAQLQGSR..
A0A3P8SYT2_AMPPE/395-425             ...TDEQRLLSLKEQLRRKSELLKQRLAQLQSSR..
A0A099ZEV6_TINGU/216-246             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSC..
MYCA_DANRE/378-408                   ..l-DEQRLLSIKEQLRRKSEQLKHRLQQLRSSH..
A0A3B4Z8C5_9TELE/343-371             ..g-EGHRLQAKRDKLKAKQEELKARLAALRS--..
A0A3Q2GX67_HORSE/368-397             ...AEEQKLVSEKDLLRKRREHLQLKLEQLRNC-..
A0A3Q3C4V1_HAPBU/363-393             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLSS--pq
B2RSN1_MOUSE/423-453                 ...ADEHKLTSEKDLLRKRREQLKHKLEQLRNS-g.
R0L9E7_ANAPL/354-384                 ...SDEHRLIAEKELLRRRREQLKHKLEQLRNSR..
A0A3Q1GE53_9TELE/336-366             ...EDESRLLTAKDELRKRSRELKHRLQQLRT--lr
C0H9V6_SALSA/355-383                 ..l-EGQRLNAKRDKLRDGQEQLKAKLEQLRR--..
A0A3B3YKH8_9TELE/399-429             ...SDEQRLMSLKEQLRRKSELLKQRLAQLQGSR..
A0A2Y9JAX5_ENHLU/408-438             ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
A0A3P8S730_AMPPE/344-374             ...EDERRLLTMKDELRKRSRELKHTLQQLRT--lh
A0A3Q7S0M0_VULVU/408-438             ...AEEQKLLSEKDLLRKRREQLKHKLEQLRNS-g.
A0A2Y9QX77_TRIMA/407-437             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A2I4C604_9TELE/396-426             ...SDEQRLVSLKEQLRRRSELLKQRLAQLQGCR..
MYC_CALJA/407-437                    ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A401P8C1_SCYTO/439-469             ...SNEQRLITEKEKLRRKQEQLKHRLEQLRNS-s.
A0A3P9CQ97_9CICH/406-436             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
A0A3Q2WS04_HAPBU/358-388             .eq--ERKLLAKKDELRKRSRELKQRLQQLRTSH..
W5U5R6_ICTPU/363-392                 ...TEERKLLNSKEQLRKKCEHLKRRLDLLSSS-..
A0A3M0KQK8_HIRRU/386-416             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNCC..
A0A2K5CX16_AOTNA/432-462             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
M3ZII1_XIPMA/401-431                 ...SDEQRLVSLKEQLRRKSELLKQRLAQLQGSR..
A0A3Q3G5Z0_9LABR/449-479             ...SDEQRLLSVKEQLRRRSELLKQKLSQLQG--ar
A0A3B4AJH1_9GOBI/370-400             ...SDEQRLVSVKEQLRRKSELLKQRLSQLQACR..
A0A3B4U1J8_SERDU/385-415             ...SDEQRLLSLKEQLRRKSELLKQRLAQLQGSR..
A0A3B3HY75_ORYLA/425-455             ...SDEQRLISFKEQLRRKSELLKQRLAQLQGSR..
A0A3B3HWZ7_ORYLA/496-526             ...SDEQRLISFKEQLRRKSELLKQRLAQLQGSR..
H0WRX5_OTOGA/421-451                 ...AEEQKLISEKDLLRKGREQLKHKLEQLRNSC..
A0A2K5CX06_AOTNA/407-437             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A2K5CX21_AOTNA/418-448             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A494C1T8_HUMAN/308-338             ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
A0A4D9EF12_9SAUR/377-407             ...TDEHRLIAEKEQLRKRREQLKHKLEQLRNSC..
M7BQH3_CHEMY/271-301                 ...TDEHRLIAEKEQLRKRREQLKHKLEQLRNSC..
A0A3P8QZL5_ASTCA/338-368             .eq--ERKLLAKKDELRKRSRELKQRLQQLRTSH..
A0A3P8XSJ1_ESOLU/376-406             ...TDEQRLVSLKEQLRRKSEHLKHKLAQLQNS-n.
A0A2U3XF43_LEPWE/407-437             ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
A0A3B4D5H7_PYGNA/358-387             ...AEERRLLTVKEQLRRRCEHLKQRLEQLSSS-..
A0A3Q3LZ53_9TELE/347-373             ..a---HRLQSKRDKLRAKQEELKARLEQLRS--..
A0A1U7RVT0_ALLSI/207-237             ...TDEHRLIAEKEQLRRRRDQLKHKLEQLRNSC..
A0A3B3T8U2_9TELE/386-416             ...TDERRLLQHKEEQRRRGERLRHRLEQLRDCH..
A0A2U4B2V6_TURTR/408-438             ...AEEQKLISEKDELRKRREQLKLKLEQLRNSC..
F6X065_MONDO/442-472                 ...AEEQKLSTESELLRKEQLQLKLKLERLQNSC..
A0A2K6AZF0_MACNE/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
Q6P1T1_XENTR/387-416                 ...EDERRLIRETEQLKYRREQLKQRLQQLRN--l.
A0A3Q1HUT1_ANATE/351-381             ..g-DERRLLKTKDELRKRSRELRQRLEQLRT--lh
Q9DFB9_ICTPU/359-389                 ...ADERRLLSMKEQLRRKSELLKHRLQQLRRSQ..
A0A2R8ZTP3_PANPA/423-453             ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
A0A1S3NCS6_SALSA/410-440             ...TDEQRLVNFKEQLTRKSEHLKQKLARLQDSH..
A0A060VPY2_ONCMY/363-393             ...TDEQRLVNFKEQLRRKSEHLKQKLARLQNSH..
F7FXT9_ORNAN/151-181                 ...AEEHKLIAEKEQLRRRREQLKHKLEQLRNFC..
A0A3Q0T508_AMPCI/335-365             ...EEERKLLAKKDGLRKRSRELKQRLQQLRT--lh
A0A3B4GZL3_9CICH/338-368             .eq--ERKLLAKKDELRKRSRELKQRLQQLRTSH..
W5PDV5_SHEEP/392-422                 ...AEEQKLISEKDVLRKRREQLKLKLEQIRNSC..
K7FM32_PELSI/293-323                 ...TDEHRLIAEKEQLKKRRDQLKHKLDQLRNSC..
A0A3P9AB27_ESOLU/375-405             ...SDEQKLLSLKEQLRGKREKLKQRLEQLRNSQ..
MYC_PIG/408-438                      ...AEEQKLVSEKDVLRKRREQLKLKLEQLRNSC..
A0A402F259_9SAUR/504-534             ...TDEHRLIAEKEQLRRRREQLKSKLQQLRNSC..
F1RC36_DANRE/379-409                 ..l-DEQRLLSIKEQLRRKSEQLKHRLQQLRSSH..
MYC_CHICK/385-415                    ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSR..
L5K5M7_PTEAL/409-439                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A1S3FVS9_DIPOR/401-431             ..v-EEQKLASEKDLLRKRREQLKHKLEQLRNSC..
A0A3Q2C645_CYPVA/333-361             ...SESHRLRARKDKLRARQEELKARLAQLRR--..
G3NKK9_GASAC/368-398                 ...TDEQRLLSLKEQLRRKSELLRQRLAHLHSSR..
H3BC94_LATCH/382-412                 ...AEEQRLTVEKEQLRRKREQLKHKLAQLQS--fh
H0YBT0_HUMAN/422-452                 ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
A0A3Q3MII7_9TELE/364-394             ...EDERRLLKMKDELRKRSRELKHRLERLRTSH..
MYC_CANLF/408-438                    ...AEEQKLLSEKDLLRKRREQLKHKLEQLRNS-g.
F1QDI6_DANRE/331-360                 ...SENQRLTSKRDKLRERQEQLKARLEQLKR--h.
A0A3L8T3N9_CHLGU/387-417             ...SEEHRLIAEKEQLRRRREQLKHKLEQLRNCC..
A0A3Q2ZA23_KRYMA/340-370             ...EEERRLLAMKDTLTKRSRELRRRLQQLRT--fs
W5MZP7_LEPOC/368-398                 ...ADEQRLISLKEQLRRKSEQLKHRLAQLRS--ph
A0A2K6MCC6_RHIBE/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
G3SNI5_LOXAF/411-440                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNS-..
A0A2K5YPL3_MANLE/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A340X7X5_LIPVE/409-439             ...AEEQKLISEKDELRKRREQLKLKLEQLRNSC..
A0A3B3U9Y0_9TELE/399-429             ...SDEQRLVSLKEQLRRKSELLKQRLAQLQGSR..
A0A3P9NAH7_POERE/415-445             ...ADERRLLKKKDELTKRSRELQRRLERLRT--lh
A0A384BZF2_URSMA/231-261             ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
A0A452IP49_9SAUR/377-407             ...TDEHRLITEKEQLRKRREQLKHKLEQLRNSC..
H2PR71_PONAB/422-452                 ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3B3X6D2_9TELE/394-424             ...SDEQRLMSLKEQLRRKSELLKQRLAQLQGSR..
G9KC04_MUSPF/422-452                 ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
A0A3Q7WL24_URSAR/408-438             ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
A0A3P8YS79_ESOLU/356-384             ..l-EGQRLNDKRDKLRERQEQLKVKLEQLRR--..
A0A1D5R6Y1_MACMU/423-453             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3Q3W929_MOLML/381-411             ...TDEQRLLSLKEQLSRKSELLKQRLAQLQGSR..
A0A096N777_PAPAN/408-438             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A060W9P8_ONCMY/340-367             ..g---QRLNDKRDKLRERQEQLKVKLEQLRR--q.
A0A3Q3WKH5_MOLML/343-371             ..d-EGHRLQSKRDRLRAKQEELKARLEQLRS--..
A0A3P9NIJ9_POERE/391-421             ...SDEQRLVSLKEQLRRKSELLKQRLAQLQGSR..
A0A3B3XDM1_9TELE/352-382             ...ADERRLLKKKDELTKRSRELQRRLERLRT--lh
A0A0Q3Q8U6_AMAAE/385-415             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSC..
G5B9M9_HETGA/361-391                 ...AEEQSLLSQKDLLRKRREQLKHRVEQLRNS-s.
A0A3B5BGJ5_9TELE/407-437             ...TDEQRLLSLKEQLRRKSELLKQRLAQLQSSR..
A0A1S3LUE5_SALSA/369-399             ..m-DEQKLLLLKEQLRKKSEQLTSRLEQLRNSQ..
G1KL38_ANOCA/449-478                 ...AEEHKLMLEKEKLQARQQQLIKKLEHMQTC-..
A0A3B4Z6W3_SERLL/385-415             ...SDEQRLLSLKEQLRRKSELLKQRLAQLQGSR..
H3BC93_LATCH/362-391                 ...AEEQRLTVEKEQLRRKREQLKHKLAQLQS--l.
A0A3Q2VQL6_HAPBU/381-411             ...SDEQRLLSLKEQLRRRSEQLKQRLAHLQGCR..
MYC_BOVIN/408-438                    ...AEQQKLKSEIDVLQKRREQLKLKLEQIRNSC..
A0A3B3E2T5_ORYME/342-372             ..g-NERKLLTTKEELRKRSRELKRRLEQLRT--lh
G1M831_AILME/421-451                 ...TEEQKLISEKDLLRKRREQLKHKLEQLRNS-g.
G1QCG9_MYOLU/409-439                 ..g-EEHKLLSEKDCLRKRREQLKHKLEQLRNSC..
A0A3B4TAF5_SERDU/350-378             ..d-EGHRLQTKRDRLKARQEELKARLEQLHS--..
A0A1U7QQI6_MESAU/409-439             ...AEEHKLISEKDLLRKRREQLKHKLEQLRNS-g.
A0A2I4CR04_9TELE/322-350             ...EEEERLLTMKDTLTKRSRELRRRLEQLRT--..
A0A3B4B130_9GOBI/332-361             ede--AHRLQRKKDQLRARQEELKARLALLRS--..
A0A087WUS5_HUMAN/423-453             ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
A0A402E7S5_9SAUR/169-199             ...ADEHKLLLEKEKLHVRQQQLIKKLEHMQQTC..
A0A3Q1CVI3_AMPOC/346-376             ...EDERRLLTMKDELRKRSRELKHTLRQLRT--lh
A0A3B5B9W9_9TELE/391-421             ...TDEQRLLSLKEQLRRKSELLKQRLAQLQSS-p.
H2QWQ2_PANTR/408-438                 ...AEEQKLISEEDLLRKRREQLKHKLEQLQNSC..
A0A2K5MVB9_CERAT/408-438             ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A0P7V0S8_SCLFO/160-190             ...SDEQRLISLKEQLRRRSEHLKNRLEQLRN--lh
A0A2Y9EJZ9_PHYMC/408-438             ...AEEQKLISEKDELRKRREQLKLKLEQLRNSC..
A0A3Q2UD68_CHICK/398-428             ...SDEHRLIAEKEQLRRRREQLKHKLEQLRNSR..
MYC_MACMU/408-438                    ...AEEQKLISEKDLLRKRREQLKHKLEQLRNSC..
A0A3B4ZYU3_9TELE/340-370             ...EDEGRLLTMKDELRKRSRELEHRLEQLRTSH..
MYC_HUMAN/408-438                    ...AEEQKLISEEDLLRKRREQLKHKLEQLRNSC..
#=GR MYC_HUMAN/408-438         SS    ...HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-..
A0A1S3QA70_SALSA/367-397             ...TDEQRLVNLKEQLRRKSEHLKQKLAQLQNSC..
A0A087Y5W6_POEFO/401-431             ...SDEQRLVSLKEQLRRKSELLKQRLAQLQGSR..
F6PX41_MOUSE/422-452                 ...ADEHKLTSEKDLLRKRREQLKHKLEQLRNS-g.
A0A060WAZ1_ONCMY/370-400             ...TDEQRLVNLKEQLRRKSEHLKQKLAQLQNSC..
A0A060W4A2_ONCMY/377-405             ..l-EGQRLNAKRDKLRDGQEQLKAKLEQLRR--..
#=GC SS_cons                         ...HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-..
#=GC seq_cons                        ...u-EQ+LlScK-pLR+RpEQLKp+LEQLRsSp..
//
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