GenomeNet

Database: Pfam
Entry: NAGLU
LinkDB: NAGLU
Original site: NAGLU 
#=GF ID   NAGLU
#=GF AC   PF05089.13
#=GF DE   Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_6295 (release 7.7)
#=GF GA   23.40 23.40;
#=GF TC   24.10 23.70;
#=GF NC   22.80 23.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Glycoside_hydrolase_family_89
#=GF RN   [1]
#=GF RM   10588735
#=GF RT   Mouse model of Sanfilippo syndrome type B produced by targeted
#=GF RT   disruption of the gene encoding alpha-N-acetylglucosaminidase. 
#=GF RA   Li HH, Yu WH, Rozengurt N, Zhao HZ, Lyons KM, Anagnostaras S,
#=GF RA   Fanselow MS, Suzuki K, Vanier MT, Neufeld EF; 
#=GF RL   Proc Natl Acad Sci U S A 1999;96:14505-14510.
#=GF RN   [2]
#=GF RM   12049639
#=GF RT   Correction of mucopolysaccharidosis type IIIb fibroblasts by
#=GF RT   lentiviral vector-mediated gene transfer. 
#=GF RA   Villani GR, Follenzi A, Vanacore B, Di Domenico C, Naldini L, Di
#=GF RA   Natale P; 
#=GF RL   Biochem J 2002;364:747-753.
#=GF RN   [3]
#=GF RM   18443291
#=GF RT   Structural and mechanistic insight into the basis of
#=GF RT   mucopolysaccharidosis IIIB.
#=GF RA   Ficko-Blean E, Stubbs KA, Nemirovsky O, Vocadlo DJ, Boraston AB;
#=GF RL   Proc Natl Acad Sci U S A. 2008;105:6560-6565.
#=GF DR   INTERPRO; IPR024733;
#=GF DR   CAZY; GH89;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for
#=GF CC   the stepwise degradation of heparan sulfate [1]. Mutations on
#=GF CC   the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to
#=GF CC   Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo
#=GF CC   syndrome type B) characterised by neurological dysfunction but
#=GF CC   relatively mild somatic manifestations [2]. The structure shows
#=GF CC   that the enzyme is composed of three domains.  This central
#=GF CC   domain has a tim barrel fold [3].
#=GF SQ   1617
#=GS A0A251JAG1_MANES/161-498    AC A0A251JAG1.1
#=GS A0A453LVV5_AEGTS/212-550    AC A0A453LVV5.1
#=GS A0A1Z2L814_9ACTN/159-480    AC A0A1Z2L814.1
#=GS B4JPC0_DROGR/140-473        AC B4JPC0.1
#=GS A0A3Q2W1I7_HAPBU/141-476    AC A0A3Q2W1I7.1
#=GS A0A3B6KN42_WHEAT/185-531    AC A0A3B6KN42.1
#=GS A0A182IV01_9DIPT/138-471    AC A0A182IV01.1
#=GS D3BUP8_POLPP/1-247          AC D3BUP8.1
#=GS A0A3B5A2Z6_9TELE/94-429     AC A0A3B5A2Z6.1
#=GS B3RSM6_TRIAD/143-478        AC B3RSM6.1
#=GS A0A1G9DSE1_9SPHI/121-453    AC A0A1G9DSE1.1
#=GS H3HCZ3_PHYRM/319-658        AC H3HCZ3.1
#=GS A0A166ZZB0_9HYPO/129-468    AC A0A166ZZB0.1
#=GS A0A0W1QMK0_9SPHN/103-466    AC A0A0W1QMK0.1
#=GS A0A2G8LHJ0_STIJA/137-339    AC A0A2G8LHJ0.1
#=GS A0A2T6DJ40_9BACT/132-452    AC A0A2T6DJ40.1
#=GS A0A2D1UCK1_9SPHI/139-459    AC A0A2D1UCK1.1
#=GS R5URV0_9BACT/124-456        AC R5URV0.1
#=GS A0A022QNL3_ERYGU/65-279     AC A0A022QNL3.1
#=GS A0A2T5BXY6_9BACT/123-446    AC A0A2T5BXY6.1
#=GS A0A0D0BC70_9AGAM/133-471    AC A0A0D0BC70.1
#=GS A0A0V0RRD0_9BILA/756-1091   AC A0A0V0RRD0.1
#=GS A0A3B3TMF5_9TELE/139-474    AC A0A3B3TMF5.1
#=GS A0A314Z4X5_PRUYE/156-494    AC A0A314Z4X5.1
#=GS A0A2G2Y6V8_CAPAN/158-440    AC A0A2G2Y6V8.1
#=GS G4Z5H4_PHYSP/347-686        AC G4Z5H4.1
#=GS B2URG0_AKKM8/124-447        AC B2URG0.1
#=GS A0A1Y4DBH5_9BACT/124-441    AC A0A1Y4DBH5.1
#=GS A0A194PY25_PAPXU/130-465    AC A0A194PY25.1
#=GS A0A3S4REI1_9ACAR/100-423    AC A0A3S4REI1.1
#=GS A0A1N6WJ47_9SPHI/118-441    AC A0A1N6WJ47.1
#=GS A0A3L8RYV2_CHLGU/207-520    AC A0A3L8RYV2.1
#=GS A0A0N0YPQ7_9ACTN/147-468    AC A0A0N0YPQ7.1
#=GS A0A1Y1YJI0_9PLEO/127-464    AC A0A1Y1YJI0.1
#=GS E8V2F6_TERSS/147-498        AC E8V2F6.1
#=GS A0A2K3P030_TRIPR/367-436    AC A0A2K3P030.1
#=GS A0A2K5X2U2_MACFA/130-465    AC A0A2K5X2U2.1
#=GS I9GM40_9BACE/121-451        AC I9GM40.1
#=GS A0A399D069_9BACT/268-518    AC A0A399D069.1
#=GS A0A287P4T8_HORVV/1-167      AC A0A287P4T8.1
#=GS A0A443RCD1_9ACAR/202-537    AC A0A443RCD1.1
#=GS A0A314YU95_PRUYE/168-497    AC A0A314YU95.1
#=GS A0A2K3PQ98_TRIPR/106-175    AC A0A2K3PQ98.1
#=GS E4T4J0_PALPW/122-455        AC E4T4J0.1
#=GS W2UQA0_9FLAO/123-461        AC W2UQA0.1
#=GS K7END1_HUMAN/26-81          AC K7END1.1
#=GS W4UZY2_9BACE/106-428        AC W4UZY2.1
#=GS A0A0D9ZRP4_9ORYZ/165-494    AC A0A0D9ZRP4.1
#=GS A0A367L6Z7_9HYPO/128-468    AC A0A367L6Z7.1
#=GS A0A2C5XJJ6_9HYPO/134-475    AC A0A2C5XJJ6.1
#=GS A0A1D6DVZ8_MAIZE/1-60       AC A0A1D6DVZ8.1
#=GS A0A445N7C8_STRNE/133-454    AC A0A445N7C8.1
#=GS A0A1V1YTX4_9ACTN/1-150      AC A0A1V1YTX4.1
#=GS I7M219_TETTS/143-467        AC I7M219.1
#=GS A0A3B6LTN5_WHEAT/164-480    AC A0A3B6LTN5.1
#=GS A0A162JH58_9HYPO/126-472    AC A0A162JH58.1
#=GS C6XUW8_PEDHD/125-456        AC C6XUW8.1
#=GS A0A0V1PIT8_9BILA/801-848    AC A0A0V1PIT8.1
#=GS W9CIQ2_SCLBF/133-471        AC W9CIQ2.1
#=GS A0A182L4M9_9DIPT/214-547    AC A0A182L4M9.1
#=GS M7UGC1_BOTF1/133-471        AC M7UGC1.1
#=GS A0A445BZY6_ARAHY/158-496    AC A0A445BZY6.1
#=GS A0A2J6QBH1_9HELO/127-464    AC A0A2J6QBH1.1
#=GS D8S289_SELML/117-456        AC D8S289.1
#=GS A0A287P4I3_HORVV/151-288    AC A0A287P4I3.1
#=GS A0A232F8K8_9HYME/375-515    AC A0A232F8K8.1
#=GS A0A161LFQ9_9BACT/122-454    AC A0A161LFQ9.1
#=GS A0A1R3HHH4_COCAP/165-503    AC A0A1R3HHH4.1
#=GS W4P6U7_9BACE/356-703        AC W4P6U7.1
#=GS G1TWY4_RABIT/122-457        AC G1TWY4.1
#=GS A0A2G5CG73_AQUCA/132-470    AC A0A2G5CG73.1
#=GS A0A2G9I9P2_9LAMI/351-465    AC A0A2G9I9P2.1
#=GS J3LNW2_ORYBR/65-403         AC J3LNW2.1
#=GS A0A3M7R277_BRAPC/95-147     AC A0A3M7R277.1
#=GS A0A1Z2L5R4_9ACTN/156-477    AC A0A1Z2L5R4.1
#=GS A0A165TH21_9APHY/118-456    AC A0A165TH21.1
#=GS U2P6I3_9BACT/120-441        AC U2P6I3.1
#=GS A0A1D5R7D4_MACMU/34-122     AC A0A1D5R7D4.1
#=GS A0A2P5S1E6_GOSBA/160-490    AC A0A2P5S1E6.1
#=GS A0A0P0NGG7_9SPHI/125-447    AC A0A0P0NGG7.1
#=GS A0A3Q7GFN7_SOLLC/113-182    AC A0A3Q7GFN7.1
#=GS M0U853_MUSAM/61-123         AC M0U853.1
#=GS A0A024UQD4_9STRA/130-485    AC A0A024UQD4.1
#=GS A0A1H5KLN8_9MICO/100-431    AC A0A1H5KLN8.1
#=GS A0A1C2GL38_9SPHI/117-449    AC A0A1C2GL38.1
#=GS A0A0L8FZ71_OCTBM/372-419    AC A0A0L8FZ71.1
#=GS A0A067BSN6_SAPPC/125-445    AC A0A067BSN6.1
#=GS A0A167HQE6_9HYPO/127-464    AC A0A167HQE6.1
#=GS K4A5Z1_SETIT/166-504        AC K4A5Z1.1
#=GS F2U7C1_SALR5/141-474        AC F2U7C1.1
#=GS A0A314KNZ6_NICAT/451-522    AC A0A314KNZ6.1
#=GS A0A024URL9_9STRA/513-853    AC A0A024URL9.1
#=GS F4X3Q5_ACREC/78-413         AC F4X3Q5.1
#=GS A0A2G5F2L7_AQUCA/499-582    AC A0A2G5F2L7.1
#=GS W2L938_PHYPR/46-385         AC W2L938.1
#=GS A0A1E7JLX2_9ACTN/137-458    AC A0A1E7JLX2.1
#=GS A0A099KQH8_9GAMM/127-461    AC A0A099KQH8.1
#=GS A0A370X3Z3_9GAMM/112-431    AC A0A370X3Z3.1
#=GS I3JJY1_ORENI/136-471        AC I3JJY1.1
#=GS A0A2K1J3K4_PHYPA/160-500    AC A0A2K1J3K4.1
#=GS A6L1H1_BACV8/113-441        AC A6L1H1.1
#=GS R6SJZ5_9BACE/113-440        AC R6SJZ5.1
#=GS W1PXI1_AMBTC/152-491        AC W1PXI1.1
#=GS A0A482XQH6_LAOST/139-474    AC A0A482XQH6.1
#=GS A0A068NR67_9BACT/93-428     AC A0A068NR67.1
#=GS A0A0V1A756_9BILA/799-846    AC A0A0V1A756.1
#=GS A0A3L6SC09_PANMI/140-325    AC A0A3L6SC09.1
#=GS A0A0E0PEZ0_ORYRU/163-487    AC A0A0E0PEZ0.1
#=GS W5UM95_ICTPU/139-474        AC W5UM95.1
#=GS A0A1G7RHC4_9SPHI/119-451    AC A0A1G7RHC4.1
#=GS A0A2K6S4E7_SAIBB/16-351     AC A0A2K6S4E7.1
#=GS C5BWA9_BEUC1/120-445        AC C5BWA9.1
#=GS A0A3B3R3F0_9TELE/133-468    AC A0A3B3R3F0.1
#=GS A0A0C2S859_AMAMU/126-463    AC A0A0C2S859.1
#=GS R5BZ34_9BACE/115-442        AC R5BZ34.1
#=GS A0A0D2QZ72_GOSRA/173-348    AC A0A0D2QZ72.1
#=GS A0A1U8J157_GOSHI/173-511    AC A0A1U8J157.1
#=GS A0A3B6MWZ9_WHEAT/164-493    AC A0A3B6MWZ9.1
#=GS A0A0A0LRJ1_CUCSA/1-60       AC A0A0A0LRJ1.1
#=GS A0A0V1PJE2_9BILA/730-778    AC A0A0V1PJE2.1
#=GS A0A2U2PI24_9SPHI/130-477    AC A0A2U2PI24.1
#=GS A0A0V0U0F1_9BILA/424-759    AC A0A0V0U0F1.1
#=GS A0A401PTT7_SCYTO/1-210      AC A0A401PTT7.1
#=GS F3PSW0_9BACE/114-441        AC F3PSW0.1
#=GS A0A2U1ELY1_9MICO/109-447    AC A0A2U1ELY1.1
#=GS A0A1I0NVV7_9BACT/112-442    AC A0A1I0NVV7.1
#=GS A0A1M4X672_9BACT/115-441    AC A0A1M4X672.1
#=GS A0A419W5S3_9BACT/126-458    AC A0A419W5S3.1
#=GS A0A251Q9L9_PRUPE/1-312      AC A0A251Q9L9.1
#=GS A0A0K9XNZ8_9ACTN/129-450    AC A0A0K9XNZ8.1
#=GS V4A4A3_LOTGI/70-122         AC V4A4A3.1
#=GS A0A1E7K282_9ACTN/141-462    AC A0A1E7K282.1
#=GS A0A2Y9EHS2_PHYMC/131-466    AC A0A2Y9EHS2.1
#=GS C3YCC1_BRAFL/294-407        AC C3YCC1.1
#=GS G3PRT4_GASAC/140-475        AC G3PRT4.1
#=GS W4HD58_9STRA/130-447        AC W4HD58.1
#=GS A0A287P5R9_HORVV/2-207      AC A0A287P5R9.1
#=GS A0A0D9WAF0_9ORYZ/166-338    AC A0A0D9WAF0.1
#=GS A0A3B4UW14_SERDU/89-193     AC A0A3B4UW14.1
#=GS A0A2T6D5I2_9BACT/213-547    AC A0A2T6D5I2.1
#=GS A0A453LVZ7_AEGTS/2-200      AC A0A453LVZ7.1
#=GS A0A0L8P4C3_9ACTN/2-255      AC A0A0L8P4C3.1
#=GS A0A2T7NPH9_POMCA/138-472    AC A0A2T7NPH9.1
#=GS A0A0V1A870_9BILA/799-846    AC A0A0V1A870.1
#=GS R6EUH7_9BACE/125-472        AC R6EUH7.1
#=GS A0A1S3J3M8_LINUN/141-476    AC A0A1S3J3M8.1
#=GS A0A1C7PA97_9BACT/137-458    AC A0A1C7PA97.1
#=GS A0A2H2I087_CAEJA/137-474    AC A0A2H2I087.1
#=GS A0A0A2WHM0_BEABA/127-464    AC A0A0A2WHM0.1
#=GS A0A1Q4XLN8_9PSEU/130-465    AC A0A1Q4XLN8.1
#=GS A0A0D3LD22_9BACT/159-491    AC A0A0D3LD22.1
#=GS A0A093V078_TALMA/129-465    AC A0A093V078.1
#=GS A0A1F5L139_9EURO/123-189    AC A0A1F5L139.1
#=GS F2UT44_SALR5/480-630        AC F2UT44.1
#=GS B6HF76_PENRW/147-217        AC B6HF76.1
#=GS A0A1Y1U9Q4_9TREE/151-494    AC A0A1Y1U9Q4.1
#=GS A0A445DKI9_ARAHY/437-512    AC A0A445DKI9.1
#=GS A0A371FZJ8_MUCPR/158-459    AC A0A371FZJ8.1
#=GS A3KIM5_STRA7/139-459        AC A3KIM5.1
#=GS R5ZS95_9BACT/133-450        AC R5ZS95.1
#=GS A0A1Q5THG0_9EURO/1-125      AC A0A1Q5THG0.1
#=GS A0A3M6UCL7_9CNID/148-482    AC A0A3M6UCL7.1
#=GS A0A067FR32_CITSI/6-234      AC A0A067FR32.1
#=GS A0A1U7Y6N6_NICSY/162-507    AC A0A1U7Y6N6.1
#=GS A0A0H1BPS1_9EURO/128-466    AC A0A0H1BPS1.1
#=GS L8H6D3_ACACA/166-509        AC L8H6D3.1
#=GS A0A287P4L5_HORVV/1-128      AC A0A287P4L5.1
#=GS A0A3L6TFY6_PANMI/202-464    AC A0A3L6TFY6.1
#=GS A0A402FAR5_9SAUR/139-474    AC A0A402FAR5.1
#=GS A0A1D6DVZ6_MAIZE/166-280    AC A0A1D6DVZ6.1
#=GS A0A397I6E3_9EURO/90-427     AC A0A397I6E3.1
#=GS A0A0V1ARQ7_TRISP/795-842    AC A0A0V1ARQ7.1
#=GS G0RVM4_HYPJQ/133-470        AC G0RVM4.1
#=GS A0A1I0F422_9FIRM/772-1104   AC A0A1I0F422.1
#=GS A0A3Q3MSE5_9TELE/140-475    AC A0A3Q3MSE5.1
#=GS A0A1S4A4H7_TOBAC/162-499    AC A0A1S4A4H7.1
#=GS A0A174FPA4_9BACE/121-455    AC A0A174FPA4.1
#=GS A0A453D7L1_AEGTS/203-485    AC A0A453D7L1.1
#=GS A0A1D6DW00_MAIZE/166-503    AC A0A1D6DW00.1
#=GS A0A0B5EU81_STRA4/172-494    AC A0A0B5EU81.1
#=GS W2Q925_PHYPN/138-477        AC W2Q925.1
#=GS A0A319DMD1_9EURO/116-453    AC A0A319DMD1.1
#=GS C1E893_MICCC/386-588        AC C1E893.1
#=GS A0A0D2JWE6_9CHLO/122-483    AC A0A0D2JWE6.1
#=GS A0A453LW43_AEGTS/1-165      AC A0A453LW43.1
#=GS A0A1M6H8P4_9ACTN/149-470    AC A0A1M6H8P4.1
#=GS A0A1C4KP39_9ACTN/141-462    AC A0A1C4KP39.1
#=GS A0A2U1KBE3_ARTAN/53-93      AC A0A2U1KBE3.1
#=GS A0A1V4JQN6_PATFA/126-461    AC A0A1V4JQN6.1
#=GS A0A1D5NU78_CHICK/136-471    AC A0A1D5NU78.1
#=GS M0SCX1_MUSAM/164-502        AC M0SCX1.1
#=GS A0A103XUV1_CYNCS/156-493    AC A0A103XUV1.1
#=GS A0A3Q2FPF7_CYPVA/139-474    AC A0A3Q2FPF7.1
#=GS A0A0W8DC69_PHYNI/352-691    AC A0A0W8DC69.1
#=GS A0A1H8E1P1_9BACT/112-433    AC A0A1H8E1P1.1
#=GS A0A1Y1HYK8_KLENI/181-520    AC A0A1Y1HYK8.1
#=GS A0A3Q8UZY1_9ACTN/140-462    AC A0A3Q8UZY1.1
#=GS A0A0E0D0R7_9ORYZ/168-485    AC A0A0E0D0R7.1
#=GS A0A4D9EIS8_9SAUR/129-464    AC A0A4D9EIS8.1
#=GS Q17GA2_AEDAE/138-471        AC Q17GA2.1
#=GS A0A3B4XWU2_SERLL/140-475    AC A0A3B4XWU2.1
#=GS A0A2N6NR28_BEABA/127-464    AC A0A2N6NR28.1
#=GS A0A1Y2E756_9PEZI/131-472    AC A0A1Y2E756.1
#=GS N1QB09_PSEFD/126-463        AC N1QB09.1
#=GS B8AVM6_ORYSI/163-500        AC B8AVM6.1
#=GS A0A1C5CLI6_9ACTN/138-458    AC A0A1C5CLI6.1
#=GS A0A2P5B9U7_PARAD/9-101      AC A0A2P5B9U7.1
#=GS A0A0V1A745_9BILA/770-1017   AC A0A0V1A745.1
#=GS A0A0D2QZ72_GOSRA/343-475    AC A0A0D2QZ72.1
#=GS A0A427YHV3_9TREE/146-468    AC A0A427YHV3.1
#=GS A0A2B8AP62_9ACTN/140-460    AC A0A2B8AP62.1
#=GS A0A1U8NZG1_GOSHI/160-497    AC A0A1U8NZG1.1
#=GS B4KKH5_DROMO/139-472        AC B4KKH5.1
#=GS A0A1H6KJG7_9BACT/144-462    AC A0A1H6KJG7.1
#=GS A0A223P2V1_9SPHI/115-447    AC A0A223P2V1.1
#=GS A0A1I0MWP9_9BACT/112-431    AC A0A1I0MWP9.1
#=GS D5EU33_PRER2/112-441        AC D5EU33.1
#=GS A0A1I0GF36_9FIRM/829-1165   AC A0A1I0GF36.1
#=GS A0A142HTS4_9SPHI/119-451    AC A0A142HTS4.1
#=GS U3JD49_FICAL/40-375         AC U3JD49.1
#=GS D3B4I2_POLPP/140-471        AC D3B4I2.1
#=GS A0A482VY58_9CUCU/1-28       AC A0A482VY58.1
#=GS A0A1H9TET9_9SPHI/121-453    AC A0A1H9TET9.1
#=GS A0A444SNJ4_ARMVU/1-129      AC A0A444SNJ4.1
#=GS A0A1R3I4N4_COCAP/423-484    AC A0A1R3I4N4.1
#=GS U5Q568_9BACT/124-457        AC U5Q568.1
#=GS R7THC8_CAPTE/114-447        AC R7THC8.1
#=GS A0A0V1CCM4_TRIBR/756-803    AC A0A0V1CCM4.1
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D3BUP8_POLPP/1-247                     .........................................-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.--MG.....N.VNE......W..A...............G..N...LT............LGWMVDQRDL.QI.QILTRMRQFG.MQA.........V..........LPGFAGHVPEA................LK..S...H..Y...P.N..A............NIT.Q.LS......S.WNM.......................................---T...V...YIH-.......................--..----QSPNT.F....MSIQ.........QD..LY.G.....T.................DHFY.....NF........D..PFNELE....P......PSSDP...................................AYLK...N...C.SQSMFNNLI..AVDP....QG.....IW.................V.L...............QGWLF.....VYDT..E.....FWQP..PQ.IE.........AFLSGVP.....IGK.MIVLDLWA...DVDA............GW.K............IT....N.......YFYGH.NWI.........W..............C.....MLHNFGGRSGMYGKIPFIST.NPI..EARSL--...............SPN.........M...........V...............GTGLTPEAI......E.Q...NVIVYDLMSEMA.WR-s..............................................................................
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Q4T1S4_TETNG/3-52                      .........................................RYYQN.V....CTFSYS.SVWWDWPR........WEREIDWMA.............LN..................GINLPL.AFTGQEALWQEV-.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........--..--.-.....-.................----.....--........-..------....-......-----...................................----...-...-.---------..----....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---r..............................................................................
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A0A494G9V2_SOLLC/1-73                  .........................................-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.-----MYELG.MTP.........V..........LPAFSGNVPAA................LK..R...V..F...P.S..A............KIS.R.LG......N.WFTvns.................................dtrWCCT...Y...LLDA.......................TD..PLFIEIGKA.F....IEQQ.........L-..--.-.....-.................----.....--........-..------....-......-----...................................----...-...-.---------..----....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---kgi............................................................................
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A0A182JN52_9DIPT/1967-2034             .........................drmvgvailklkdvvd-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.--Q.......................................YFSS...L...FLDP.......................TE..PLCAEVGKR.F....LKRM.........IS..GF.G.....S.................DHIY.....FS........D..PFNEIN....P......TSRS-...................................----...-...-.---------..----....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---gr.............................................................................
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A0A1D6P9Y8_MAIZE/23-226                ..............................fyfrntvdanp-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......K.---.......................................WCCT...Y...LLDP.......................SD..SLFIDVGQA.F....IRQQ.........IK..EY.G....dV.................TNIY.....NC........D..TFNENT....P......PTDEP...................................AYIS...S...L.GSAIYEAMS..RGNK....NA.....VW.................L.M...............QGWLF.....YSDA..A.....FWKE..PQ.MK.........ALLHSVP.....IGK.MIVLDLFA...DVKP............IW.K............VS....S.......QFYGV.PYI.........W..............C.....MLHNFGGNIEMYGILDSISS.GPI..DAR-TSY...............NST.........M...........I...............GVGMCMEGI......E.H...NPVVYELMSEMA.FH-n..............................................................................
NAGLU_ARATH/157-495                    ........................................n-YYQN.V....VTSSYS.YVWWGWER........WEREIDWMA.............LQ..................GINLPL.AFTGQEAIWQKVF.K..R..FNI...SK..EDL.DDY...FGGPA.FL.AW.ARMG.....N.LHA......W..G...............G..P...LS............KNWLDDQLLL.QK.QILSRMLKFG.MTP.........V..........LPSFSGNVPSA................LR..K...I..Y...P.E..A............NIT.R.LD......N.WNTvdg.................................dsrWCCT...Y...LLNP.......................SD..PLFIEIGEA.F....IKQQ.........TE..EY.G....eI.................TNIY.....NC........D..TFNENT....P......PTSEP...................................EYIS...S...L.GAAVYKAMS..KGNK....NA.....VW.................L.M...............QGWLF.....SSDS..K.....FWKP..PQ.LK.........ALLHSVP.....FGK.MIVLDLYA...EVKP............IW.N............KS....A.......QFYGT.PYI.........W..............C.....MLHNFGGNIEMYGALDSISS.GPV..DAR-VSK...............NST.........M...........V...............GVGMCMEGI......E.Q...NPVVYELTSEMA.FR-d..............................................................................
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A0A3Q7GFP2_SOLLC/1-164                 .........................................-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.-----MYELG.MTP.........V..........LPAFSGNVPAA................LK..R...V..F...P.S..A............KIS.R.LG......N.WFTvns.................................dtrWCCT...Y...LLDA.......................TD..PLFIEIGKV.F....IEQQ.........LK..EY.G....rS.................SHIY.....NC........D..TFDENT....P......PVDDP...................................DYIS...S...L.GATIFKGMQ..SADS....DA.....VW.................L.M...............QA---.....----..-.....----..--.--.........-LLHSVP.....LGK.LIVLDLYA...EVKP............IW.A............TS....K.......QFYGI.PYI.........W..............K.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---vtllf..........................................................................
R6TB39_9BACE/123-457                   .........................................RFFLN.Y....CTFGYT.MPYWKWSD........WERLIDWMA.............LN..................GVNMPL.AITGQESIWYKVW.T..D..MGL...TD..EQI.RSY...FTGPA.HL.PW.HRMS.....N.VDY......W..Q...............S..P...LP............ESWLENQEEL.QK.KILKRERSLG.MTP.........V..........LPAFAGHVPAE................LK..Q...V..R...P.E..A............KIY.T.MS......Q.WGGy....................................ddRYRS...H...FIDP.......................ED..PLYSEIQRR.F....LEAQ.........TE..VY.G.....T.................DHIY.....GI........D..PFNEVD....S......PDWNE...................................EFLS...N...V.SKKIYKSIE..SVDK....DA.....VW.................L.Q...............MTWMF.....YHSA..E.....KWTD..SR.IE.........AFLNAVP.....ENK.LVLLDYYC...DFEE............LW.R............RT....K.......NYYGK.PYI.........W..............C.....YLGNFGGNTMLAGDIDDVDF.KIN..RLF-EEG...............GDN.........V...........F...............GVGITLEGL......D.V...NPLMYEYVFDKV.WN-p..............................................................................
G7J0U7_MEDTR/65-403                    ........................................n-YYQN.V....VTSSYS.FVWWDWER........WEKEVDWMA.............LQ..................GVNLPL.AFTGQEAIWQKVF.K..D..FNI...SS..EDL.NSF...FGGPA.FL.AW.ARMG.....N.LHG......W..G...............G..P...LS............QNWLDQQLVL.QK.QIISRMLELG.MTP.........V..........LPSFSGNVPAA................LT..K...I..F...P.S..A............KIT.R.LG......D.WNTvda.................................dprWCCT...Y...LLDP.......................SD..PLFVEIGEA.F....IRKQ.........IK..EY.G....dV.................TDIY.....NC........D..TFNENS....P......PTSDP...................................AYIS...T...L.GAAVYQGIS..KGDK....DA.....VW.................L.M...............QGWLF.....YSDS..S.....FWKP..PQ.MK.........ALLQSVP.....SGK.MIVLDLFA...DVKP............IW.K............TS....F.......QFYGT.PYI.........W..............C.....MLHNFGGNIEMYGVLDAIAS.GPV..DAR-VSE...............NST.........M...........V...............GVGMCMEGI......E.H...NPIVYELMSEMA.FR-d..............................................................................
A0A0A7CMU6_9STRA/129-469               ........................................t-YYLN.I....CTHSYS.MWTWDWTQ........WETHIDWMV.............LN..................GINMPL.AITGQEKTWQKTF.E..Y..YNV...SK..SGL.ERF...FGGAA.FL.AW.ERMG.....N.IRG.....dW..Sp.............lG..R...LP............QHFIDRQHEL.QL.QLLERYREFG.MLP.........A..........LPAFAGHVPEE................MH..V...L..F...P.N..A............SMR.K.SD......Q.WAGfd...................................lnYTCV...Y...MLDP.......................TD..PLYLEVGKK.F....LTIQ.........RE..LY.Gg...yT.................SSLY.....ST........D..TYNELK....P......HTSDH...................................EYLR...A...S.SKAVIDSMI..AADK....KA.....VW.................I.M...............QAWLF.....ISMR..D.....YWTQ..DK.IE.........AYLSGVP.....NDR.MIILDLYS...EESP............YW.A............QT....S.......NYYGK.PWI.........Y..............C.....VLHTFGGNLGMHGNLPRLSH.EPL..EALAK-S...............DGR.........M...........I...............GMGLTMEGI......F.Q...NYIVYDFSLEMN.WQ-s..............................................................................
A0A072UZT3_MEDTR/151-429               ........................................s-YYQN.A....VTSSYS.FAWWDWKR........WEKEIDWMA.............LQ..................GVNLPL.AFTGQEAIWQKVF.K..K..FNM...SI..SNL.DDF...FGGPA.FL.AW.SRMG.....N.LHG......W..G...............G..P...LP............QSWFDQQLIL.QK.KILARMYELG.MTP.........V..........LPAFSGNVPAA................LK..S...I..F...P.S..A............KIT.R.LG......N.WFSvkn.................................dlkWTCT...Y...LLDA.......................TD..PLFVEIGRA.F....AEQQ.........LQ..EY.G....rT.................SHIY.....NC........D..TFDENT....P......PIDDP...................................EYIS...S...L.GAAIFKGMQ..SGDN....DA.....VW.................L.M...............QGWLF.....S-YD..P.....FWRP..PQ.MK.........ALLHSVP.....AGK.LVVLDLFA...EVKP............IW.I............TS....E.......QFYGV.PYI.........W..............K.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---v..............................................................................
A0A1H4G5T9_9SPHI/120-452               .........................................RYYLN.Y....CTFNYT.MAWWDWER........WQKEIDWMA.............MN..................GINMPL.AITGEEAIWRDVY.R..G..MGF...SE..KEL.EGF...FSGPA.YF.SW.LWMG.....N.IDA......W..G...............G..P...LP............QHWMDSHKEL.QK.KILSRERSFG.MKP.........V..........LSAFTGHVPPS................FK..N...K..Y...P.A..A............KVK.R.T-......N.WDA......................................gFPDV...F...ILDP.......................ED..TLFEEIGKK.Y....IELQ.........TK..EF.G.....T.................DHLY.....SS........D..TFNENI....P......PTNDS...................................TYLS...D...M.SKKVFRSMT..AADP....KA.....VW.................V.M...............QGWMF.....HYNN..K.....FWQP..QQ.IK.........ALLNAIP.....NDQ.MIILDLYS...DAHP............VW.N............RT....N.......AYYGK.PWI.........W..............N.....MLQNFGGNISMFGRMRHVAA.DPA..IALHDPE...............SKN.........M...........V...............GIGLAPEGI......E.Q...NPALFELMLENV.WK-d..............................................................................
D8RVI9_SELML/117-456                   ........................................s-YYQN.V....VTSSYS.YAWWNWKR........WRKEIDWMA.............LQ..................GINLPL.AFTGQETIWQKVF.E..S.kFNM...TK..HEL.DDY...FGGPS.FL.AW.ARMG.....N.LHG......W..G...............G..P...LP............EKWLELQLIL.QK.KILHHMRSLG.MIA.........V..........LPAFSGNVPRA................LK..I...L..Y...P.S..A............NIT.R.LP......D.WNTvdg.................................npqWCCT...Y...LLQP.......................MD..PLFIQIGKA.F....IEQQ.........VK..EY.G....sT.................QHVY.....NC........D..TFNENL....P......PTDDP...................................SYIS...A...L.AASVYGAMI..VADK....QA.....IW.................L.M...............QGWLF.....SSDA..Q.....FWKP..PQ.MK.........ALLHAVP.....FGK.MIVLDLFA...EVRP............IW.S............KS....S.......HFYGV.PYI.........W..............C.....MLHNFGGNHEMYGRLDVVSS.GPV..DAK-TSA...............NST.........M...........I...............GVGMCMEGI......E.Q...NPVVYELMAEMA.FR-s..............................................................................
A0A1A6GL35_NEOLE/64-399                .........................................RYYQN.V....CTHSYS.FVWWDWAR........WEQEIDWMA.............LN..................GINLAL.AWNGQEAIWQRVY.L..A..LGL...TQ..SEI.XEY...FTGPA.FL.AW.ERMG.....N.LHT......W..G...............G..P...LS............RAWHLKQLYL.QH.RILDRMRSFG.MIP.........V..........LPAFAGHVPKA................IT..R...V..F...P.Q..V............NVT.Q.LG......S.WGHfn...................................csYSCS...F...LLAP.......................GD..PVFPLIGSL.F....LREL.........TK..EF.G.....T.................DHIY.....GA........D..TFNEMQ....P......PSSDP...................................SYLT...A...A.TVAVYEAMI..AVDP....DA.....LW.................L.L...............QGWLF.....QHQP..Q.....FWGP..AQ.IK.........AVLEAVP.....RGR.LLVLDLFA...ESQP............VY.I............HT....A.......SFHGQ.PFI.........W..............C.....MLHNFGGNHGLFGTLEAVNQ.GPR..AAR-LFP...............NST.........M...........V...............GTGIVPEGI......G.Q...NEVVYALMAELG.WRK...............................................................................
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A0A498JL34_MALDO/158-496               ........................................n-YYQN.V....VTSSYS.FVWWDWER........WQKEIDWMA.............LQ..................GINLPL.AFTGQESIWQKVF.M..D..FNI...SK..EDL.NDF...FGGSA.FL.AW.ARMG.....N.LHA......W..G...............G..P...LS............QNWLDQQLVL.QK.QILSRMLELG.MTP.........V..........LPSFSGNVPVT................LK..K...V..Y...P.S..A............NIT.R.LG......E.WNTvdg.................................dprWCCT...Y...LLDP.......................SD..PLFVEIGMA.F....VRRQ.........VE..EY.G....dV.................TDIY.....NC........D..TFNENT....P......PTNDT...................................AYIS...S...L.GAAVYKAMS..KGDK....DA.....VW.................L.M...............QGWLF.....YSDS..A.....FWKP..PQ.MK.........ALLHSVP.....FGK.MIVLDLFA...DVKP............IW.K............TS....S.......QFYGT.PYI.........W..............C.....LLHNFGGNIEMYGILDAISS.GPV..DAR-TSE...............NST.........M...........V...............GVGMCMEGI......E.H...NPVVYELTSEMA.FR-s..............................................................................
A0A2P8PYJ7_9ACTN/103-424               .........................................RVAYN.L....TVGGYT.TPFYDWAQ........WEHEIDLLA.............AG..................GVNAAH.LTLGQELAYLNTF.L..R..YGY...DE..QEI.LQW...LGPPS.HQ.PW.LWLN.....N.IQN......F..G...............R..G...IS............RALVNNRATL.AR.RVIEQMQELD.ICP.........I..........LPGFSGTVPPD................FS..K...H..H...A.G..A............RTV.P.QG......R.WFKdv...................................agPIRP...D...WLDT.......................TT..HAYASVATT.F....YREQ.........RA..AF.G.....T.................TGMW.....AV........D..LIHEGG....-......-STGG...................................TDLG...S...A.ACGVQKAMT..AANP....DA.....TW.................V.M...............QAWAG.....----..-.....----..NP.RR.........ELLDAID.....TDR.VLVLDLTG...EHH-............--.-............HE....D.......GFGGT.DWV.........L..............G.....ILPNYGGRTALYGDLADVAA.LPL..QWRHGHR...............APG.........L...........V...............GLANMAEGV......G.N...NPVLWDLFNDLT.WA-g..............................................................................
G4Z5K8_PHYSP/46-385                    ........................................s-YYQN.V....CTVSYS.SWAWGWQK........WEKHIDWMA.............LN..................GINMPL.AFTGQEKVWQNTF.K..K.hYNV...SS..AGL.NKF...FAGAA.FL.AW.GRMG.....N.LRG.....sW.vE...............G..P...LP............QAFIDGQYEL.QL.KILERMRGFG.MVP.........A..........LPAFAGHVPEE................LK..T...L..Y...P.N..A............KFT.R.SP......N.WGGfs...................................deFCCV...Y...MLDP.......................QD..PLYYEIGKT.F....LEEQ.........RA..LY.D....yT.................SSLY.....QC........D..TYNEMD....P......DFTDP...................................AKLQ...A...A.SRAVIDSMT..AADP....NA.....VW.................L.I...............QGWLF.....VNSP..N.....YWTK..ER.VQ.........TYLDGVP.....NDK.MIILDLYS...EVRP............VW.N............KM....D.......NYFGK.SWI.........Y..............C.....VLHNFGGNTGMRGDLPTLGT.APV..LAN-RAS...............SGT.........M...........I...............GMGLTMEGI......F.Q...NYVVYDLTLQMA.WV-d..............................................................................
A0A2A2JCH2_9BILA/241-406               .......................................pl-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........RE..NF.G....nV.................THIY.....SA........D..PYNEMK....P......TVKKL...................................SDLK...H...M.AEGIYAGAS..AIDK....KA.....IW.................M.L...............QGWAF.....FA--..D.....KWTK..QE.VK.........AFLSGVP.....LGR.LIVLDLIA...EASP............LW.N............VF....N.......SFYGH.HFI.........W..............C.....LLHNFGGTTEMRGNLRQINK.GYQ..LALTSP-...............-NS.........M...........V...............GAGLAMEAI......N.Q...NYIVYQFTIDRM.WS-n..............................................................................
A0A139WIN2_TRICA/127-462               .........................................RYYQN.V....CTTSYS.FVWWDWTQ........WEKHIDWMV.............LN..................GFNLVL.AFNGQEAIWDRVY.K..K..FNL...TR..EEI.DEH...FSGPA.FL.SW.LRMG.....N.MRG......F..G...............G..P...LS............PAWHSRSLVL.QK.QILQRMRAFG.IIP.........V..........LPAFAGHLPRA................FK..T...L..Y...P.D..A............NMS.K.MA......P.WNGfn...................................dtYCCP...Y...FLDP.......................TE..PLFNEIGKA.F....LSEQ.........IS..EF.G.....T.................DHMY.....NC........D..SFNENV....P......TSGDL...................................TYLA...N...V.GKSIYKAMT..DTDP....DA.....VW.................L.L...............QGWMF.....-YND..N.....FWQD.tER.VR.........SILTSVP.....LGK.MIVLDLQS...EQFP............QY.E............RL....N.......QYFGQ.PYI.........W..............C.....MLHDFGGTLGMFGSSTVINE.VPI..KAR-HLE...............NST.........M...........I...............GTGLTPEGI......N.Q...NYVIYELMTETA.WRQ...............................................................................
A0A287P4K5_HORVV/1-312                 .........................................-----.-....------.--------........-------MA.............LQ..................GINLPL.AFTGQEAVWQKVF.K..S..FNV...TD..RDL.DDF...FGGPA.FL.AW.ARMG.....N.LHA......W..G...............G..P...LS............QIWLDQQLAL.QK.KILSRMIELG.MVP.........V..........LPSFSGNVPVA................FK..K...L..F...P.S..A............SIT.R.LG......D.WNTidg.................................nprWCCT...Y...ILDP.......................SD..ALFIDVGQA.F....IKQQ.........MK..EY.G....dI.................TSIY.....NC........D..TFNENT....P......PTNEP...................................TYIS...S...L.GSAIYEAMS..RGNK....DA.....VW.................L.M...............QGWLF.....YSDA..V.....FWKE..SQ.MK.........ALLHSVP.....IGK.MMVLDLFA...DVKP............IW.Q............TS....S.......QFYGV.PYI.........W..............C.....MLHNFGGNIEMYGVLDSISS.GPV..DAR-TSY...............NST.........M...........V...............GVGMCMEGI......E.H...NPVVYELMSEMA.FR-s..............................................................................
A0A2H5NAA2_CITUN/156-468               ........................................n-YYQN.V....VTS-NS.YVWWEWER........WEKEIDWMA.............LQ..................GINLPL.AFDGQEAIWQKVF.M..N..FNV...TM..EDL.NDF...FSGPA.FL.AW.ARMG.....N.LHG......W..G...............G..P...LA............QNWLNQQLVL.QK.KIVSRMLELG.MTP.........V..........LPSFAGNVPAA................LK..K...I..F...P.S..A............NIT.R.LG......D.WNTvdr.................................nprWCCT...Y...LLDP.......................TD..PLFVEIGEA.F....IKQQ.........IA..EY.G....dV.................TDIY.....NC........D..TFNENT....P......PTNDT...................................NYIS...S...L.GAAVYKAMS..EGDK....DA.....VW.................L.M...............QA---.....----..-.....----..--.--.........-LLHSVP.....LGK.MIVLDLFA...EVKP............IW.R............TS....S.......Q----.---.........-..............C.....MLHNFGGNIEIYGILDSIAS.GPV..DAR-VSE...............NST.........M...........V...............GVGMCMEGI......E.Q...NPVVYELMSEMA.FR-n..............................................................................
A0A3M7R277_BRAPC/141-370               .......................................ik-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.-VSNGYRELG.ISY.........V..........LPAFAGFVPDQ................IR..R...I..Y...P.F..N............NFT.S.AS......D.WIG.......................................---L...T...MVDP.......................LD..PLFSRIGIA.Y....NREV.........IR..LF.G.....P.................SGFY.....SA........D..VFNEML....P......KSGDL...................................DYLA...I...V.NQAVYDSLI..AVDE....NA.....IW.................V.M...............QGWVF.....--NQ..D.....FWNR..TR.VE.........AFLSRIP.....IGR.LIILDLFS...ETIP............HF.N............DF....S.......SYFGH.SFV.........W..............N.....MLHNFGGANGIFGDIEKINQ.LPD..KAR-KLP...............NSS.........M...........I...............GVGITMEGI......D.Q...NEMIYEFMLEKT.WRQ...............................................................................
A0A2T3ZNR6_9HYPO/128-465               .........................................RYHWN.T....VTTSYT.SAFWSWED........WETQLDWMA.............LR..................GVNLAL.AWIGVEKIFIDVF.T..D..IGL...NE..EEI.NSF...ISGPA.FL.AW.NHFG.....N.IQG.....sW..N...............G..N...MP............DNWVDDQFAL.QL.QILDRMKELG.ITP.........I..........LPAFPGFVPRN................IS..R...V..F...P.G..I............SLS.T.SP......L.WENfa...................................edFSAD...T...YVNP.......................FD..PHFTQLQKL.F....IGKQ.........QE..LY.G....nV.................TKFW.....TL........D..QFNENQ....P......LSSDL...................................GYLR...N...V.SQNTWTALK..SASP....DA.....IW.................V.M...............QAWLF.....SADS..A.....FWTN..DA.IE.........AFLGGIT....eDSD.MLLLDLFA...ESAP............QW.L............RT....N.......SFYGK.PWI.........W..............C.....ELHDYGGNMGLYGQIENVTI.NAM..QAVRN--...............SSS.........L...........V...............GFGLTMEGQ......E.G...NEIMYDLLLDQA.WS-s..............................................................................
A0A452QT00_URSAM/83-418                .........................................RYYQN.V....CTHSYS.FVWWDWAR........WERELDWMA.............LN..................GINLAL.AWSGQEAIWQRVY.L..A..LGL...TQ..SEI.DEY...FTGPA.FL.AW.GRMG.....N.LHT......W..G...............G..P...LP............RSWHLKQLYL.QH.RILDRMRSFG.MIP.........V..........LPAFAGHVPKA................LT..R...V..F...P.Q..V............NIT.Q.LG......S.WGHfn...................................csYSCS...F...LLAP.......................ED..PLFPIIGSL.F....LREL.........TK..EF.G.....T.................DHIY.....GA........D..TFNEMQ....P......PSSEP...................................SYLA...A...A.TASVYQAMI..TVDP....EA.....VW.................L.L...............QGWLF.....QHQP..E.....FWGP..AQ.VR.........AVLGAVP.....HGR.LLVLDLFA...ESQP............VY.T............RT....A.......SFHGQ.PFI.........W..............C.....MLHNFGGNHGLFGALEAVNR.GPA..AAR-LFP...............NST.........M...........A...............GTGMAPEGI......G.Q...NEMVYALMAELG.WRK...............................................................................
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I1PQC5_ORYGL/163-441                   ........................................s-YYQN.A....VTSSYS.FAWWDWER........WEKEIDWMA.............LQ..................GINLPL.AFTGQEAIWQKVF.Q..R..YNI...SK..SDL.DDF...FGGPA.FL.AW.SRMA.....N.MHG......W..G...............G..P...LP............QSWLDDQLAL.QK.KILSRMYAFG.MFP.........V..........LPAFSGNIPAA................LR..S...K..F...P.S..A............KVT.H.LG......N.WFTvds.................................nprWCCT...Y...LLDA.......................SD..PLFVEIGKL.F....IEEQ.........IR..EY.G....gT.................SHVY.....SC........D..TFDENT....P......PLSDP...................................NYIS...S...L.GAATFRGMQ..SGDD....DA.....IW.................L.M...............QGWLF.....S-YD..P.....FWEP..PQ.MK.........ALLHSVP.....VGR.MIVLDLYA...EVKP............IW.I............NS....D.......QFYGV.PYI.........W..............K.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---v..............................................................................
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A0A0W7X0T7_9ACTN/148-484               .........................................RFVLN.D....TNDGYT.NAYADWDY........WERELDVLA.............LH..................GYNEVL.VYAGADAVYHRLF.Q..E..FGY...GD..EEL.RAW...VPGPA.HQ.PW.WLLQ.....N.MQN......T..QnlqdlqnlqdlsacpH..P...LS............RQLLDKRARL.GR.RIADRVRELG.MTP.........V..........FPGYFGTVPDG................FA..E...R..N...P.G..A............RTV.P.QG......T.WTG.......................................LARP...D...WLDP.......................RT..EAFARVAAA.F....YRVQ.........DE..LF.G.....P.................STMY.....KM........D..LLHEGG....-......-KPGD...................................VPVG...D...A.AKAVEKALR..TAHP....DA.....VW.................V.I...............LGWQH.....----..-.....----..NP.PK.........ALVDAVD.....TSR.MLVVDGLS...DRYP...........tVT.D............RE....S.......DWGST.PYA.........F..............G.....SIWNFGGHTALGANTPDWAD.LYE..KWR-TKD...............GST.........L...........R...............GVALMPEAA......D.N...NPAAFALFSELA.WRD...............................................................................
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A0A3E2HJ24_SCYLI/747-1084              .........................................RYHFN.T....VTFSYT.AAFWTWED........WELELDWLA.............LR..................GVNLPL.AWVGYEKILLDVY.R..E..IGM...TD..AEI.ISF...FSGPA.FQ.AW.NRFG.....N.EQG.....sW..G...............G..E...LP............LSWIDSQFDL.QK.KIVKRMVELG.MTP.........V..........LPAFTGFVPAS................FT..R...V..R...P.S..A............NVV.N.GS......Q.WSGfp...................................ssYTND...T...FLEP.......................DD..PSFAQLQKS.L....ISKQ.........IS..AY.G....nI.................THIY.....TL........D..QYNENN....P......FSGDL...................................GYLR...N...V.TYNTWKSLK..AADT....EA.....IW.................M.M...............QGWLF.....FSSS..S.....FWTN..ER.IE.........AYLGGVE....dNSD.MLILDLFS...ESQP............QW.Q............RT....N.......SYYGK.PWI.........W..............C.....QLHDYGGNMGLYGQVMNVTL.NPI..EALAN--...............SSS.........L...........V...............GFGLTMEGQ......E.G...NEIVYDLLLDQA.WSK...............................................................................
L1KX91_9ACTN/146-468                   .........................................RFALN.D....TNDGYT.GAYLDWTY........WERELDVLA.............LH..................GYNEVL.VYAGADALYHRVF.Q..E..FGY...RD..EEL.REW...IAGPA.HQ.PW.WLLQ.....N.LSS......F..P...............S..P...VS............RQLLDARAAL.GR.RIVGRLRELG.MTP.........V..........FPGYFGTVPPG................FA..E...R..N...P.G..A............RTV.P.QG......D.WMG.......................................FARP...D...WLDP.......................RT..NEFKRVAAA.F....YRAQ.........DE..LF.G....gP.................STLY.....KM........D..LLHEGG....-......-DPGD...................................VPVA...D...A.AKGVERALR..AAHP....DA.....TW.................V.I...............LGWQH.....----..-.....----..NP.PR.........AIVDAVD.....KKR.MLVVDGLS...DRFP...........tVI.D............RE....A.......DWGDT.PYA.........F..............G.....SIWNFGGHTALGANTPVWAE.LYE..KWR-TKD...............GSK.........L...........R...............GIALMPEAA......D.N...NPAAFALFSELA.WRK...............................................................................
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A0A386HT87_9BACT/123-446               .........................................RYALN.Y....CTYNYT.MSFWTWQQ........WEKELDWMS.............LN..................GVNLML.APIGTEAVWQKTL.Q..Q..LGV...SD..KEI.RDF...IPGPA.FN.AW.WLMG.....N.LEG......W..G...............G..P...VS............DAMINHWASL.QK.RILIRMSELG.INP.........V..........IQGFEGIVPST................LK..D...H..Y...P.K..S............NII.D.QG......T.WCG.......................................FQRP...A...VLVA.......................TD..PLFKKIAKL.Y....YSNF.........KA..LY.G....nG.................FKYL.....GG........D..LFHEGG....-......-RTNS...................................IDLV...E...E.AKLVQQNMQ..QNFP....NA.....TW.................V.L...............QGWQD.....----..-.....----..NP.KV.........KMMAGLN.....PEH.TLIIDLLG...DRTE............TW.L............QR....N.......QYGNF.PWI.........W..............S.....TISNFGGRTTTGGTLMRVLT.EPK..KAERIFG..............kKCT.........L...........K...............GTGIIPEGI......E.N...NAIIYQWALDGA.WH-k..............................................................................
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A0A069D539_9BACE/25-114                .........................................RYNFN.Y....CTFSYS.MAFWDWKR........WEQEIDWMA.............LH..................SINLPL.AVVGEECIWFNML.K..K..LGY...SK..EEI.NKF...ISGPA.FM.AW.WEMN.....N.LEG......W..G...............G..P...NP............DS--------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........--..--.-.....-.................----.....--........-..------....-......-----...................................----...-...-.---------..----....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---cq.............................................................................
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A0A3N2NMI7_9BACT/529-858               .........................................RYYLN.Y....CTHSYS.MAFWDWER........WQKEIDWMA.............LH..................GINMPL.AITGTDVVWRNTL.L..R..LGY...SK..KEA.DEF...VAGPA.FQ.AW.WLMN.....N.LEG......W..G...............G..P...NS............EKWYEDRAEL.QD.KILTRMRELG.MEP.........V..........LPGYSGMVPHD................AE..E...R..L...G.M..-............DVS.G.KG......I.WNG.......................................FVRP...T...FLKS.......................TD..PQFNKIADI.Y....YDEL.........RK..VS.G.....V.................AKYY.....SM........D..PFHEGG....-......-SIEG...................................VDLT...E...A.GKIIAGAMK..RANP....EA.....VW.................V.I...............QGWNE.....----..-.....----..NP.RA.........KLYAGIP.....KGD.IVVLDLAS...EIKP............QW.Gdpdt...psktpRP....T.......GYDGQ.DWL.........W..............C.....MLLNFGGNVGLHGRLDNVIG.GYY..KARDSRF...............GKD.........M...........T...............GIGLTPEGI......E.N...NPVMYELVSELI.WR-p..............................................................................
A0A067FUG4_CITSI/1-242                 .........................................-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.--MS.....N.LHG......W..G...............G..P...LP............QSWLDQQLVL.QK.KILVRIYELG.MNP.........V..........LPAFSGNVPAA................LQ..N...V..F...P.S..A............KIT.Q.LG......N.WFSvks.................................dprWCCT...Y...LLDA.......................TD..PLFIEIGRA.F....IEQQ.........LK..EY.G....rT.................SHIY.....NC........D..TFDENT....P......PVDSP...................................EYIS...S...L.GAAIYSGMQ..SGDS....DA.....VW.................L.M...............QGWLF.....S-YD..P.....FWRP..PQ.MK.........ALLNSVP.....LGK.LVVLDLFA...EVKP............IW.S............TS....K.......QFYGV.PYI.........W..............C.....MLHNFAGNIEMYGILDSIAF.GPV..EARTS-E...............NTT.........M...........-...............---------......-.-...------------.---awinq..........................................................................
A0A0E0G1Q3_ORYNI/169-226               ........................................n-YYQN.V....VTSSYS.FVWWDWKR........WEKEIDWMA.............LQ..................GINLPL.AFTGQEAIWQKM-.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........--..--.-.....-.................----.....--........-..------....-......-----...................................----...-...-.---------..----....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---gwttitkla......................................................................
A0A3Q7GFN7_SOLLC/1-102                 ........................................m-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........--..--.-.....-.................-SIY.....CS........D..TFDENT....P......PVDDP...................................DYIS...S...L.GATIFKGMQ..SADS....DA.....VW.................L.M...............QGWLF.....TYD-..P.....FWRP..TQ.MK.........ALLHSVP.....LGK.LIVLDLYA...EVKP............IW.A............TS....K.......QFYGI.PYI.........W..............K.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---lav............................................................................
A0A287P4J3_HORVV/1-312                 .........................................-----.-....------.--------........-------MA.............LQ..................GINLPL.AFTGQEAVWQKVF.K..S..FNV...TD..RDL.DDF...FGGPA.FL.AW.ARMG.....N.LHA......W..G...............G..P...LS............QIWLDQQLAL.QK.KILSRMIELG.MVP.........V..........LPSFSGNVPVA................FK..K...L..F...P.S..A............SIT.R.LG......D.WNTidg.................................nprWCCT...Y...ILDP.......................SD..ALFIDVGQA.F....IKQQ.........MK..EY.G....dI.................TSIY.....NC........D..TFNENT....P......PTNEP...................................TYIS...S...L.GSAIYEAMS..RGNK....DA.....VW.................L.M...............QGWLF.....YSDA..V.....FWKE..SQ.MK.........ALLHSVP.....IGK.MMVLDLFA...DVKP............IW.Q............TS....S.......QFYGV.PYI.........W..............C.....MLHNFGGNIEMYGVLDSISS.GPV..DAR-TSY...............NST.........M...........V...............GVGMCMEGI......E.H...NPVVYELMSEMA.FR-s..............................................................................
S4RFB5_PETMA/123-458                   .........................................RFYQN.V....RTRSYS.MVWWQWER........WELEIDWMA.............LQ..................GINLPL.AFTGHEAIWQRVF.L..S..LGL...TQ..KEM.DDY...FTGPA.FL.AW.SQLG.....N.LHA......W..A...............G..P...LP............QSWHHKQLHL.QR.KILERMRSLG.MIT.........V..........LPAFEGYVPAA................VA..R...L..Y...P.K..A............NLI.R.LS......S.WDRfd...................................cnYSCP...L...WLDP.......................HD..PLFPKLASA.Y....MKEL.........RD..EF.G.....S.................DHAY.....YA........T..MFSELM....P......PSNLT...................................ADLA...G...I.SGAVYKAMT..AVDS....EA.....VW.................L.L...............DTWPF.....LCNP..N.....FWQE..PQ.LR.........AFLRGPP.....LGH.VLVLDVFA...ETRP............LH.R............TT....G.......SFYGQ.PFI.........W..............C.....MLHNFGGNHGLFGAIESVNR.GPH..AAR-LLP...............NSS.........M...........V...............GTGMAPEGI......E.Q...NDVIYELMAEMG.WRD...............................................................................
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A0A287JHA9_HORVV/1-60                  .........................................-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........--..--.-.....-.................----.....--........-..------....-......-----...................................----...-...-.---------..----....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....MLHNFAADFEMYGVLDAVAS.GPI..DAR-LSE...............NST.........M...........V...............GVGMSMEGI......E.Q...NPIVYDLMSEMV.FH-h..............................................................................
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K7ESD7_HUMAN/1-45                      ........................................x-----.-....------.--------........---------.............--..................------.-------------.-..-..---...--..---.---...-----.--.--.----.....-.---......-..-...............-..-...--............----------.--.----------.---.........-..........-----------................--..-...-..-...-.-..-............---.-.--......-.---.......................................----...-...----.......................--..---------.-....----.........--..-F.G.....T.................DHIY.....GA........D..TFNEMQ....P......PSSEP...................................SYLA...A...A.TTAVYEAMT..AV--....--.....--.................-.-...............-----.....----..-.....----..--.--.........-------.....---.--------...----............--.-............--....-.......-----.---.........-..............-.....--------------------.---..-------...............---.........-...........-...............---------......-.-...------------.---lgarp..........................................................................
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