GenomeNet

Database: Pfam
Entry: Na_Ca_ex
LinkDB: Na_Ca_ex
Original site: Na_Ca_ex 
#=GF ID   Na_Ca_ex
#=GF AC   PF01699.25
#=GF DE   Sodium/calcium exchanger protein
#=GF PI   Na_Ca_Ex; 
#=GF AU   Bashton M;0000-0002-6847-1525
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Pfam-B_1680 (release 4.1)
#=GF GA   24.90 22.00;
#=GF TC   24.90 22.00;
#=GF NC   24.70 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8798769
#=GF RT   Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3. 
#=GF RA   Nicoll DA, Quednau BD, Qui Z, Xia YR, Lusis AJ, Philipson KD; 
#=GF RL   J Biol Chem 1996;271:24914-24921.
#=GF RN   [2]
#=GF RM   1700476
#=GF RT   Molecular cloning and functional expression of the cardiac
#=GF RT   sarcolemmal Na(+)-Ca2+ exchanger. 
#=GF RA   Nicoll DA, Longoni S, Philipson KD; 
#=GF RL   Science 1990;250:562-565.
#=GF DR   INTERPRO; IPR004837;
#=GF DR   TC; 2.A.19;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of sodium/calcium exchanger integral membrane
#=GF CC   proteins. This family covers the integral membrane regions of
#=GF CC   the proteins. Sodium/calcium exchangers regulate intracellular
#=GF CC   Ca2+ concentrations in many cells; cardiac myocytes, epithelial
#=GF CC   cells, neurons retinal rod photoreceptors and smooth muscle
#=GF CC   cells [2]. Ca2+ is moved into or out of the cytosol depending on
#=GF CC   Na+ concentration [2].  In humans and rats there are 3 isoforms;
#=GF CC   NCX1 NCX2 and NCX3 [1] see Swiss:Q01728, Swiss:P48768 and
#=GF CC   Swiss:P70549 respectively.
#=GF SQ   35512
#=GS A0A3L8SRU5_CHLGU/86-257     AC A0A3L8SRU5.1
#=GS A0A2U8GTY4_9RHOO/4-145      AC A0A2U8GTY4.1
#=GS A0A1M5EXT3_9ACTN/30-190     AC A0A1M5EXT3.1
#=GS A0A1Y0H4A4_9BACT/3-145      AC A0A1Y0H4A4.1
#=GS W4KBB5_9AGAM/119-278        AC W4KBB5.1
#=GS A0A199UTD9_ANACO/96-283     AC A0A199UTD9.1
#=GS A0A2P4Z9P3_9HYPO/104-246    AC A0A2P4Z9P3.1
#=GS G3PJL4_GASAC/23-168         AC G3PJL4.1
#=GS A0A091CUR3_FUKDA/77-248     AC A0A091CUR3.1
#=GS A0A067KJJ6_JATCU/62-220     AC A0A067KJJ6.1
#=GS A0A2R6QET2_9APHY/543-737    AC A0A2R6QET2.1
#=GS H9IXJ4_BOMMO/59-203         AC H9IXJ4.1
#=GS J9DHP1_9PROT/168-311        AC J9DHP1.1
#=GS R0LJ11_ANAPL/77-248         AC R0LJ11.1
#=GS L9W2I4_9EURY/171-313        AC L9W2I4.1
#=GS K7FBI5_PELSI/78-249         AC K7FBI5.1
#=GS W5JWW9_ANODA/334-487        AC W5JWW9.1
#=GS A0A162TF66_MUCCL/671-808    AC A0A162TF66.1
#=GS A0A146G063_9EURO/75-231     AC A0A146G063.1
#=GS A0A0E3Z260_9GAMM/170-313    AC A0A0E3Z260.1
#=GS S9SK44_9RHOB/1-142          AC S9SK44.1
#=GS A0A168N4S9_ABSGL/235-380    AC A0A168N4S9.1
#=GS A0A1U7WE43_NICSY/275-420    AC A0A1U7WE43.1
#=GS A0A395LIE5_9SPHN/1-143      AC A0A395LIE5.1
#=GS A0A0B5DWR6_9RHOB/24-166     AC A0A0B5DWR6.1
#=GS A0A1E1L058_9HELO/266-385    AC A0A1E1L058.1
#=GS V4A5G9_LOTGI/322-464        AC V4A5G9.1
#=GS I3KQF1_ORENI/123-267        AC I3KQF1.1
#=GS A0A0E3NVU1_9EURY/1-84       AC A0A0E3NVU1.1
#=GS S2IYN4_MUCC1/78-223         AC S2IYN4.1
#=GS A0A2S4HDG4_9GAMM/3-145      AC A0A2S4HDG4.1
#=GS A0A077Z2Y7_TRITR/60-231     AC A0A077Z2Y7.1
#=GS A0A498RBX0_9FIRM/3-158      AC A0A498RBX0.1
#=GS A0A397T326_9GLOM/446-634    AC A0A397T326.1
#=GS H5XSD2_9FIRM/24-177         AC H5XSD2.1
#=GS A0A2K5IX93_COLAP/444-596    AC A0A2K5IX93.1
#=GS A0A1S4AN07_TOBAC/383-535    AC A0A1S4AN07.1
#=GS A0A367KAL5_9FUNG/52-209     AC A0A367KAL5.1
#=GS M0CY93_9EURY/248-397        AC M0CY93.1
#=GS E0UJH5_CYAP2/27-183         AC E0UJH5.1
#=GS A4UQV6_DANRE/79-250         AC A4UQV6.1
#=GS A0A1Y3VGS9_9BACT/179-323    AC A0A1Y3VGS9.1
#=GS A0A1U7LP38_NEOID/268-413    AC A0A1U7LP38.1
#=GS A0A182K8I4_9DIPT/7-121      AC A0A182K8I4.1
#=GS A0A011M8I9_9PROT/174-319    AC A0A011M8I9.1
#=GS A0A017S8W6_9EURO/856-1011   AC A0A017S8W6.1
#=GS A0A317PRR0_9RHIZ/3-145      AC A0A317PRR0.1
#=GS A0A1N6ER24_9BRAD/33-189     AC A0A1N6ER24.1
#=GS Q31RP5_SYNE7/9-151          AC Q31RP5.1
#=GS M5FYW1_DACPD/861-1014       AC M5FYW1.1
#=GS A0A1A0LZ24_9MYCO/27-184     AC A0A1A0LZ24.1
#=GS D3F1N9_CONWI/37-192         AC D3F1N9.1
#=GS A0A369GUB6_9HYPO/302-447    AC A0A369GUB6.1
#=GS A0A1M6B6L5_MALRU/5-147      AC A0A1M6B6L5.1
#=GS A0A409Y861_9AGAR/335-497    AC A0A409Y861.1
#=GS U3J7G3_ANAPP/741-906        AC U3J7G3.2
#=GS A0A1Y5T2H6_9RHOB/175-318    AC A0A1Y5T2H6.1
#=GS A0A401S5P6_CHIPU/348-498    AC A0A401S5P6.1
#=GS A0A2Y9NWI3_DELLE/454-598    AC A0A2Y9NWI3.1
#=GS Q2UEZ7_ASPOR/8-152          AC Q2UEZ7.1
#=GS A0A2H3ITJ7_9EURO/107-277    AC A0A2H3ITJ7.1
#=GS A0A175YEV8_DAUCS/128-289    AC A0A175YEV8.1
#=GS A0A3B4AZS4_9GOBI/85-256     AC A0A3B4AZS4.1
#=GS A0A077J912_9BACI/210-354    AC A0A077J912.1
#=GS R5AXM3_9BACE/178-322        AC R5AXM3.1
#=GS A0A0L8HN91_OCTBM/304-456    AC A0A0L8HN91.1
#=GS A0A0Q3TGA8_AMAAE/135-278    AC A0A0Q3TGA8.1
#=GS V4AY93_LOTGI/391-542        AC V4AY93.1
#=GS A0A2P4ZS69_9HYPO/36-193     AC A0A2P4ZS69.1
#=GS I3JCX7_ORENI/23-167         AC I3JCX7.1
#=GS A0A1I0MEG2_9EURY/9-147      AC A0A1I0MEG2.1
#=GS A0A2M9C902_9FLAO/222-366    AC A0A2M9C902.1
#=GS A0A1V6U3F8_9EURO/43-201     AC A0A1V6U3F8.1
#=GS F9XFX1_ZYMTI/39-180         AC F9XFX1.1
#=GS A0A151N4M3_ALLMI/19-130     AC A0A151N4M3.1
#=GS A0A1U8PEM8_GOSHI/492-646    AC A0A1U8PEM8.1
#=GS U5HDQ1_USTV1/72-244         AC U5HDQ1.1
#=GS W7Q8K7_9ALTE/4-145          AC W7Q8K7.1
#=GS D8JBK1_HALJB/29-185         AC D8JBK1.1
#=GS A0A3Q1BGD3_AMPOC/342-507    AC A0A3Q1BGD3.1
#=GS A0A1I7T5M6_9PELO/71-145     AC A0A1I7T5M6.1
#=GS A0A2K6BCP9_MACNE/356-508    AC A0A2K6BCP9.1
#=GS A0A367YLR4_9ASCO/604-788    AC A0A367YLR4.1
#=GS U3IP75_ANAPP/255-406        AC U3IP75.2
#=GS A0A383ZP38_BALAS/502-653    AC A0A383ZP38.1
#=GS A0A0V1NRU6_9BILA/675-842    AC A0A0V1NRU6.1
#=GS A0A0A0AJS9_CHAVO/23-167     AC A0A0A0AJS9.1
#=GS A0A1X6Z5M2_9RHOB/2-144      AC A0A1X6Z5M2.1
#=GS A0A3Q2UTD4_HAPBU/74-245     AC A0A3Q2UTD4.1
#=GS A0A2W0CP66_9MICO/8-162      AC A0A2W0CP66.1
#=GS A0A1I8ED18_WUCBA/75-235     AC A0A1I8ED18.1
#=GS A0A1B1Q3U5_9CHLB/24-173     AC A0A1B1Q3U5.1
#=GS A0A2A2J6P8_9BILA/532-630    AC A0A2A2J6P8.1
#=GS A0A165BDS2_9APHY/654-803    AC A0A165BDS2.1
#=GS W9WQP1_9EURO/112-291        AC W9WQP1.1
#=GS B4IM41_DROSE/12-155         AC B4IM41.1
#=GS A0A212R309_9CHLR/198-343    AC A0A212R309.1
#=GS A0BTS9_PARTE/4-152          AC A0BTS9.1
#=GS A0A395MI19_9HYPO/851-1016   AC A0A395MI19.1
#=GS C6PQ21_9CLOT/3-160          AC C6PQ21.1
#=GS S0EBD2_GIBF5/78-266         AC S0EBD2.1
#=GS R1DUD8_EMIHU/152-296        AC R1DUD8.1
#=GS A0A182VJF5_ANOME/392-547    AC A0A182VJF5.1
#=GS A0A178BBZ1_9PLEO/275-420    AC A0A178BBZ1.1
#=GS A0A0E0JK34_ORYPU/278-423    AC A0A0E0JK34.1
#=GS A6TEL5_KLEP7/174-318        AC A6TEL5.1
#=GS R7EWF4_9BACT/3-153          AC R7EWF4.1
#=GS A0A0K9RRD3_SPIOL/366-532    AC A0A0K9RRD3.1
#=GS K6Z0H5_9ALTE/3-145          AC K6Z0H5.1
#=GS A0A0K6IXB8_9PROT/9-151      AC A0A0K6IXB8.1
#=GS A0A1B8D386_9PEZI/89-251     AC A0A1B8D386.1
#=GS A0A2G2Z8D9_CAPAN/270-415    AC A0A2G2Z8D9.1
#=GS A0A2P2BPW7_9FIRM/177-319    AC A0A2P2BPW7.1
#=GS B4S9G7_PROA2/5-152          AC B4S9G7.1
#=GS T0SWU1_9PROT/168-309        AC T0SWU1.1
#=GS A0A3P2AC45_9BACE/1-151      AC A0A3P2AC45.1
#=GS A0A1E5R5C7_9ASCO/28-209     AC A0A1E5R5C7.1
#=GS A0A197KEU5_9FUNG/302-447    AC A0A197KEU5.1
#=GS A0A1G8T2Q5_9RHOB/4-145      AC A0A1G8T2Q5.1
#=GS A0A3R6LM53_9FIRM/5-148      AC A0A3R6LM53.1
#=GS A0A1I4MK84_9PSED/172-319    AC A0A1I4MK84.1
#=GS A0A3Q0SKY5_AMPCI/784-949    AC A0A3Q0SKY5.1
#=GS A0A2U9B298_SCOMX/631-776    AC A0A2U9B298.1
#=GS F2K1A4_MARM1/3-145          AC F2K1A4.1
#=GS U5C7F0_9BACT/1-143          AC U5C7F0.1
#=GS A0A127CPV8_9RHIZ/219-363    AC A0A127CPV8.1
#=GS A0A0G2K3S9_RAT/103-246      AC A0A0G2K3S9.1
#=GS A0A0D2C289_9EURO/445-590    AC A0A0D2C289.1
#=GS A0A364KUD1_9EURO/148-306    AC A0A364KUD1.1
#=GS A0A410PTJ5_9FIRM/202-346    AC A0A410PTJ5.1
#=GS K1WHK7_MARBU/321-465        AC K1WHK7.1
#=GS C4GJI4_9NEIS/47-203         AC C4GJI4.1
#=GS A0A423Q0X9_9GAMM/8-154      AC A0A423Q0X9.1
#=GS A0A067SH20_GALM3/92-253     AC A0A067SH20.1
#=GS Q8T8P0_STRPU/117-260        AC Q8T8P0.1
#=GS W5NTH6_SHEEP/46-190         AC W5NTH6.1
#=GS G0W3S1_NAUDC/258-403        AC G0W3S1.1
#=GS A0A1M5VPX5_9GAMM/6-148      AC A0A1M5VPX5.1
#=GS U9T3N0_RHIID/80-239         AC U9T3N0.1
#=GS A0A1S3EME4_DIPOR/456-600    AC A0A1S3EME4.1
#=GS A5E209_LODEL/108-260        AC A5E209.1
#=GS A0A1S9CG10_9FIRM/179-321    AC A0A1S9CG10.1
#=GS A0A0B4XGM2_9RHIZ/214-358    AC A0A0B4XGM2.1
#=GS D2VSE3_NAEGR/480-630        AC D2VSE3.1
#=GS A0A0C5WWB3_9GAMM/174-318    AC A0A0C5WWB3.1
#=GS A0A150G5D7_GONPE/564-727    AC A0A150G5D7.1
#=GS A0A142XTY1_9BACT/178-321    AC A0A142XTY1.1
#=GS A0A151S6N2_CAJCA/483-637    AC A0A151S6N2.1
#=GS A0A1V6PS64_9EURO/104-276    AC A0A1V6PS64.1
#=GS A0A1I8MXX2_MUSDO/105-249    AC A0A1I8MXX2.1
#=GS A0A058ZGW4_9RHOB/3-143      AC A0A058ZGW4.1
#=GS I4Z9K5_9BACT/3-145          AC I4Z9K5.1
#=GS A0A1L9NSM7_9RHOB/1-142      AC A0A1L9NSM7.1
#=GS A0A419Y9B1_9MICO/231-375    AC A0A419Y9B1.1
#=GS A0A367K8H2_9FUNG/66-227     AC A0A367K8H2.1
#=GS A0A072VCB3_MEDTR/98-257     AC A0A072VCB3.1
#=GS A0A3Q1J0U8_ANATE/138-282    AC A0A3Q1J0U8.1
#=GS T1IAG7_RHOPR/16-160         AC T1IAG7.1
#=GS CAX4_ARATH/291-436          AC Q945S5.2
#=GS K9YK71_CYASC/209-355        AC K9YK71.1
#=GS A0A318KLK2_9FIRM/165-307    AC A0A318KLK2.1
#=GS A0A168AIV1_9HYPO/676-822    AC A0A168AIV1.1
#=GS R0J9V1_ANAPL/115-265        AC R0J9V1.1
#=GS A0A1D8S5E4_9EURY/228-377    AC A0A1D8S5E4.1
#=GS A0A1B8EB59_9PEZI/413-559    AC A0A1B8EB59.1
#=GS H2Z6E7_CIOSA/23-196         AC H2Z6E7.1
#=GS A0A0P6WNS7_9CHLR/209-354    AC A0A0P6WNS7.1
#=GS R0IC12_9BRAS/431-577        AC R0IC12.1
#=GS A0A2K6FFJ1_PROCO/795-960    AC A0A2K6FFJ1.1
#=GS I0I102_CALAS/3-145          AC I0I102.1
#=GS A0A3Q1GAF2_9TELE/382-517    AC A0A3Q1GAF2.1
#=GS A0A388LJQ8_CHABU/327-475    AC A0A388LJQ8.1
#=GS A0A494WBH6_9SPHN/3-145      AC A0A494WBH6.1
#=GS D8R2N6_SELML/195-338        AC D8R2N6.1
#=GS C0QQ55_PERMH/180-329        AC C0QQ55.1
#=GS L0KVH3_METHD/4-146          AC L0KVH3.1
#=GS A0A2L0PJ15_VITS1/2-115      AC A0A2L0PJ15.1
#=GS R0IC03_SETT2/912-1067       AC R0IC03.1
#=GS A0A173YSQ5_9FIRM/12-161     AC A0A173YSQ5.1
#=GS A0A395SXF2_9HYPO/83-240     AC A0A395SXF2.1
#=GS A0A167WUI4_9PEZI/182-350    AC A0A167WUI4.1
#=GS M0SC36_MUSAM/247-391        AC M0SC36.1
#=GS U4LCR0_PYROM/568-757        AC U4LCR0.1
#=GS A0A3P9PPE7_POERE/92-236     AC A0A3P9PPE7.1
#=GS A0A1B0BEG6_9MUSC/471-623    AC A0A1B0BEG6.1
#=GS D0D061_9RHOB/1-143          AC D0D061.1
#=GS A0A2D0SSZ6_ICTPU/788-953    AC A0A2D0SSZ6.1
#=GS A0A445IGL5_GLYSO/33-207     AC A0A445IGL5.1
#=GS A0A3B3D6T0_ORYME/124-268    AC A0A3B3D6T0.1
#=GS G7PV94_MACFA/71-216         AC G7PV94.1
#=GS A0A2Z6E4D0_9GAMM/3-161      AC A0A2Z6E4D0.1
#=GS A0A1S3BKH0_CUCME/3-136      AC A0A1S3BKH0.1
#=GS A0A0A2WHZ5_9GAMM/38-187     AC A0A0A2WHZ5.1
#=GS E0UID0_CYAP2/27-183         AC E0UID0.1
#=GS A0A2S4PKU2_9PEZI/93-234     AC A0A2S4PKU2.1
#=GS A0A1Y6BNG9_9PROT/3-145      AC A0A1Y6BNG9.1
#=GS A0A0A8VX24_PAESO/1-151      AC A0A0A8VX24.1
#=GS K4C3U3_SOLLC/368-534        AC K4C3U3.1
#=GS A0A0D2CZ87_9EURO/153-322    AC A0A0D2CZ87.1
#=GS C4Z6E0_EUBE2/51-200         AC C4Z6E0.1
#=GS A0A2A9NYN7_9AGAR/666-814    AC A0A2A9NYN7.1
#=GS A0A2S7PRK7_9HELO/82-262     AC A0A2S7PRK7.1
#=GS A0A0K9QJN5_SPIOL/274-420    AC A0A0K9QJN5.1
#=GS A0A3Q2UT72_HAPBU/100-271    AC A0A3Q2UT72.1
#=GS A0A498ND67_LABRO/123-267    AC A0A498ND67.1
#=GS A0A0Q7TNM5_9RHIZ/214-358    AC A0A0Q7TNM5.1
#=GS A0A0D2AJ16_9EURO/78-236     AC A0A0D2AJ16.1
#=GS A0A0H4VV10_9BORD/187-328    AC A0A0H4VV10.1
#=GS A0A369HJ63_9HYPO/173-327    AC A0A369HJ63.1
#=GS A0A218Z9Y6_9HELO/87-273     AC A0A218Z9Y6.1
#=GS E0CSC2_VITVI/80-260         AC E0CSC2.1
#=GS A0A3B3UP30_9TELE/146-290    AC A0A3B3UP30.1
#=GS A0A091WM94_NIPNI/1-142      AC A0A091WM94.1
#=GS A0A2U9CHN7_SCOMX/747-912    AC A0A2U9CHN7.1
#=GS A0A366JT30_9RHOB/4-144      AC A0A366JT30.1
#=GS A0A0K8QT37_9BACT/172-316    AC A0A0K8QT37.1
#=GS A0A1S3PET3_SALSA/439-591    AC A0A1S3PET3.1
#=GS A0A1H9SD37_9BACI/1-150      AC A0A1H9SD37.1
#=GS A0A0N4TLF6_BRUPA/34-212     AC A0A0N4TLF6.1
#=GS A0A3P9C8U2_9CICH/81-252     AC A0A3P9C8U2.1
#=GS A0A3P5WYZ1_9RHOB/1-143      AC A0A3P5WYZ1.1
#=GS A0A2Y9RXN1_TRIMA/424-575    AC A0A2Y9RXN1.1
#=GS A0A1R3JC99_9ROSI/387-533    AC A0A1R3JC99.1
#=GS H6C797_EXODN/102-280        AC H6C797.1
#=GS A0A099ZTJ3_TINGU/78-249     AC A0A099ZTJ3.1
#=GS A0A2G4SUM4_RHIZD/47-205     AC A0A2G4SUM4.1
#=GS A0A327Y1A6_RHIET/223-369    AC A0A327Y1A6.1
#=GS R5XZA7_9CLOT/3-145          AC R5XZA7.1
#=GS A0A3B0M9Q7_9RHOB/1-143      AC A0A3B0M9Q7.1
#=GS A0A2G3E064_9FIRM/186-328    AC A0A2G3E064.1
#=GS A0A416ECS6_9FIRM/1-152      AC A0A416ECS6.1
#=GS A0A0I9UKY3_9MYCO/219-363    AC A0A0I9UKY3.1
#=GS A0A1I7GLN3_9CLOT/1-149      AC A0A1I7GLN3.1
#=GS A0A2J6PZ78_9HELO/162-324    AC A0A2J6PZ78.1
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#=GS A0A2G3E064_9FIRM/12-161     AC A0A2G3E064.1
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#=GS A0A3B3UWA5_9TELE/17-188     AC A0A3B3UWA5.1
#=GS W4FIG2_9STRA/251-395        AC W4FIG2.1
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#=GS A0A3P9B655_9CICH/67-243     AC A0A3P9B655.1
#=GS F3Z3L1_DESAF/208-357        AC F3Z3L1.1
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#=GS A0A2A9PDW6_9HYPO/424-574    AC A0A2A9PDW6.1
#=GS A0A3P8N6A4_ASTCA/131-275    AC A0A3P8N6A4.1
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#=GS A0A182PDA0_9DIPT/433-588    AC A0A182PDA0.1
#=GS J3NS66_GAGT3/158-323        AC J3NS66.1
#=GS A0A1I5WFF4_9RHOB/1-139      AC A0A1I5WFF4.1
#=GS A0A1T5KPD3_9CLOT/169-312    AC A0A1T5KPD3.1
#=GS A0A370GL87_9NOCA/166-308    AC A0A370GL87.1
#=GS A0A059FUM7_9RHOB/171-328    AC A0A059FUM7.1
#=GS A0A195BQQ7_9HYME/60-204     AC A0A195BQQ7.1
#=GS A0A1G7MUL8_9PROT/2-140      AC A0A1G7MUL8.1
#=GS A0A482SP45_9ARCH/61-215     AC A0A482SP45.1
#=GS A0A066Z1I7_9ACTN/34-189     AC A0A066Z1I7.1
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#=GS U3AB07_9EURY/214-369        AC U3AB07.1
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#=GS A0A2K5WMN4_MACFA/80-251     AC A0A2K5WMN4.1
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#=GS E9EQT3_METRA/96-263         AC E9EQT3.1
#=GS G2NPS3_STREK/57-230         AC G2NPS3.1
#=GS A0A3B3Z9D7_9GOBI/127-271    AC A0A3B3Z9D7.1
#=GS A0A0V1ABF7_9BILA/61-232     AC A0A0V1ABF7.1
#=GS A0A372RVV9_9GLOM/48-215     AC A0A372RVV9.1
#=GS A0A0F4YS92_TALEM/966-1132   AC A0A0F4YS92.1
#=GS A0A3N4H311_9BACT/174-318    AC A0A3N4H311.1
#=GS E3M3D5_CAERE/118-262        AC E3M3D5.1
#=GS A0A3G2S7P3_9BASI/452-605    AC A0A3G2S7P3.1
#=GS A0A452FKG2_CAPHI/77-248     AC A0A452FKG2.1
#=GS A0A2K6TQ21_SAIBB/501-652    AC A0A2K6TQ21.1
#=GS H3SPP3_9BACL/208-353        AC H3SPP3.1
#=GS A0A0D2R1L5_GOSRA/77-257     AC A0A0D2R1L5.1
#=GS A0A0G4J343_PLABS/389-542    AC A0A0G4J343.1
#=GS A4SVP5_POLAQ/198-342        AC A4SVP5.1
#=GS D8RBT7_SELML/433-585        AC D8RBT7.1
#=GS A0A427XPK4_9TREE/255-423    AC A0A427XPK4.1
#=GS F6FPC5_ISOV2/182-327        AC F6FPC5.1
#=GS A6UUX7_META3/6-147          AC A6UUX7.1
#=GS Q7QCY1_ANOGA/79-250         AC Q7QCY1.5
#=GS A0A0K8LEE9_9EURO/828-987    AC A0A0K8LEE9.1
#=GS A0A1Q3ET95_LENED/302-446    AC A0A1Q3ET95.1
#=GS A0A0P8XYN7_DROAN/123-294    AC A0A0P8XYN7.1
#=GS A0A096P1G5_PAPAN/501-652    AC A0A096P1G5.2
#=GS A0A021WW37_DROME/86-230     AC A0A021WW37.1
#=GS A0A1Y2VF33_9PEZI/175-336    AC A0A1Y2VF33.1
#=GS A0A226N6P4_CALSU/1-138      AC A0A226N6P4.1
#=GS A0A0M2Q1Z5_PROHO/177-322    AC A0A0M2Q1Z5.1
#=GS A0A1Y2MGC1_EPING/282-427    AC A0A1Y2MGC1.1
#=GS A0A0A2K225_PENEN/858-1024   AC A0A0A2K225.1
#=GS A0A0N4YIH4_NIPBR/1-126      AC A0A0N4YIH4.1
#=GS A0A2H3Y6M9_PHODC/93-254     AC A0A2H3Y6M9.1
#=GS A0A453HY67_AEGTS/18-157     AC A0A453HY67.1
#=GS M3ZTZ2_XIPMA/476-628        AC M3ZTZ2.1
#=GS A0A150ANW1_9BACT/183-325    AC A0A150ANW1.1
#=GS A0A1A6A606_9TREE/184-352    AC A0A1A6A606.1
#=GS A0A0K0Y057_9GAMM/3-145      AC A0A0K0Y057.1
#=GS A0A2T7CBS4_9POAL/385-528    AC A0A2T7CBS4.1
#=GS A0A2H5PAQ2_CITUN/105-263    AC A0A2H5PAQ2.1
#=GS A0A3G8JRA6_9ACTN/170-313    AC A0A3G8JRA6.1
#=GS W9J7P8_9HYPO/108-271        AC W9J7P8.1
#=GS H2YTJ1_CIOSA/712-883        AC H2YTJ1.1
#=GS M1BWC6_SOLTU/479-633        AC M1BWC6.1
#=GS A0A2T7F482_9POAL/212-358    AC A0A2T7F482.1
#=GS A0A1Y2W070_9PEZI/297-441    AC A0A1Y2W070.1
#=GS C6A3K6_THESM/165-308        AC C6A3K6.1
#=GS A0A2I4CCJ5_9TELE/108-252    AC A0A2I4CCJ5.1
#=GS NAC1_CANLF/796-961          AC P23685.1
#=GS A7E4V6_SCLS1/114-280        AC A7E4V6.1
#=GS A0A1Z4RQS3_9CHRO/209-355    AC A0A1Z4RQS3.1
#=GS R0JRL4_SETT2/114-283        AC R0JRL4.1
#=GS N1QE57_SPHMS/143-317        AC N1QE57.1
#=GS A0A022MD49_9ACTN/132-276    AC A0A022MD49.1
#=GS A0A1L8G7D8_XENLA/337-489    AC A0A1L8G7D8.1
#=GS A0A3P9C8U2_9CICH/773-938    AC A0A3P9C8U2.1
#=GS C6HT34_AJECH/304-447        AC C6HT34.1
#=GS A0A267F6L7_9PLAT/714-879    AC A0A267F6L7.1
#=GS W6WI51_9RHIZ/37-188         AC W6WI51.1
#=GS A0A0T1SBU7_9ACTN/31-189     AC A0A0T1SBU7.1
#=GS A0A165TAI9_9APHY/328-473    AC A0A165TAI9.1
#=GS H0VP36_CAVPO/450-587        AC H0VP36.2
#=GS E6U1C0_BACCJ/174-316        AC E6U1C0.1
#=GS F6ZB51_MACMU/273-424        AC F6ZB51.2
#=GS A0A0J0XV30_9TREE/733-884    AC A0A0J0XV30.1
#=GS A0A150XIS3_9BACT/172-313    AC A0A150XIS3.1
#=GS A0A1G5SHX9_9PROT/6-148      AC A0A1G5SHX9.1
#=GS O83997_TREPA/16-163         AC O83997.1
#=GS R7H8M6_9FIRM/12-161         AC R7H8M6.1
#=GS A0A0P7IWZ5_9RHOB/2-143      AC A0A0P7IWZ5.1
#=GS A0A251SCG9_HELAN/142-289    AC A0A251SCG9.1
#=GS A0A3B5AV13_9TELE/424-576    AC A0A3B5AV13.1
#=GS F8J545_HYPSM/22-178         AC F8J545.1
#=GS A0A2G2WAJ6_CAPBA/244-399    AC A0A2G2WAJ6.1
#=GS A0A061DQ54_THECC/93-273     AC A0A061DQ54.1
#=GS A0A1X2I189_9FUNG/83-225     AC A0A1X2I189.1
#=GS A0A3P8SGJ9_AMPPE/353-505    AC A0A3P8SGJ9.1
#=GS A0A256KEI5_9EURY/187-331    AC A0A256KEI5.1
#=GS A0A1H6ZB68_9FIRM/3-160      AC A0A1H6ZB68.1
#=GS B2WEX1_PYRTR/539-728        AC B2WEX1.1
#=GS T0R9B0_SAPDV/384-542        AC T0R9B0.1
#=GS A0A2G4SX38_RHIZD/86-228     AC A0A2G4SX38.1
#=GS A0A158P9X3_ANGCA/50-154     AC A0A158P9X3.1
#=GS A0A0J1F8C1_9FIRM/3-159      AC A0A0J1F8C1.1
#=GS M5DUE0_9GAMM/170-316        AC M5DUE0.1
#=GS A0A1I2UP27_9GAMM/3-145      AC A0A1I2UP27.1
#=GS A0A166Z7E7_9GAMM/3-145      AC A0A166Z7E7.1
#=GS A0A2P5R8G4_GOSBA/492-646    AC A0A2P5R8G4.1
#=GS A0A2R8Z6S8_PANPA/77-248     AC A0A2R8Z6S8.1
#=GS CAX1C_ORYSJ/293-438         AC Q5KTQ9.1
#=GS A0A1Q8S7Q1_9PEZI/194-349    AC A0A1Q8S7Q1.1
#=GS A0A1V4JWH6_PATFA/592-737    AC A0A1V4JWH6.1
#=GS A0A2S4KW36_9HYPO/573-707    AC A0A2S4KW36.1
#=GS A0A2D0R9T4_ICTPU/69-240     AC A0A2D0R9T4.1
#=GS NCKX2_CHICK/488-639         AC Q9IAL7.1
#=GS A0A452FUF8_CAPHI/452-596    AC A0A452FUF8.1
#=GS A0A1L7I734_9FLAO/168-314    AC A0A1L7I734.1
#=GS A0A151QYG9_CAJCA/554-702    AC A0A151QYG9.1
#=GS A0A0P7IWZ5_9RHOB/177-320    AC A0A0P7IWZ5.1
#=GS I1AW76_9RHOB/9-156          AC I1AW76.1
#=GS D4GV88_HALVD/190-333        AC D4GV88.1
#=GS A0A1G4M845_LACFM/248-393    AC A0A1G4M845.1
#=GS E2RS44_CANLF/72-216         AC E2RS44.1
#=GS A0A2U2N7N0_9GAMM/3-145      AC A0A2U2N7N0.1
#=GS K9YAP9_HALP7/220-365        AC K9YAP9.1
#=GS A0A0Q7D786_9CAUL/213-357    AC A0A0Q7D786.1
#=GS A0A1Q8S2M5_9PEZI/116-276    AC A0A1Q8S2M5.1
#=GS A0A1S3RG82_SALSA/145-289    AC A0A1S3RG82.1
#=GS A0A0K0E3L7_STRER/146-289    AC A0A0K0E3L7.1
#=GS A0A2K5MZ88_CERAT/77-248     AC A0A2K5MZ88.1
#=GS K6YGH6_9ALTE/172-318        AC K6YGH6.1
#=GS M9PCP1_DROME/687-837        AC M9PCP1.1
#=GS A0A0Q9Z8Y4_9FLAO/3-153      AC A0A0Q9Z8Y4.1
#=GS A0A2A2WFI6_9PLAN/241-344    AC A0A2A2WFI6.1
#=GS CHAA_BACSU/205-350          AC O34840.1
#=GS CHAA_BACSU/205-350          DR PDB; 4KJS B; 205-350;
#=GS CHAA_BACSU/205-350          DR PDB; 4KJR A; 205-350;
#=GS CHAA_BACSU/205-350          DR PDB; 4KJS A; 205-350;
#=GS CHAA_BACSU/205-350          DR PDB; 4KJR B; 205-350;
#=GS A0A453N963_AEGTS/110-268    AC A0A453N963.1
#=GS A0A1L9VLT0_ASPGL/487-676    AC A0A1L9VLT0.1
#=GS A0A284QUD8_9AGAR/366-511    AC A0A284QUD8.1
#=GS H3BW27_TETNG/126-219        AC H3BW27.1
#=GS A0A0D9NY30_METAN/9-152      AC A0A0D9NY30.1
#=GS M3Y897_MUSPF/103-246        AC M3Y897.1
#=GS E6QZN2_CRYGW/58-233         AC E6QZN2.1
#=GS A0A125MFY9_BACSE/1-151      AC A0A125MFY9.1
#=GS A0A037ZD34_9RHOB/5-141      AC A0A037ZD34.1
#=GS A0A1M6F9H1_9RHOB/172-315    AC A0A1M6F9H1.1
#=GS A0A2D0QF01_ICTPU/432-583    AC A0A2D0QF01.1
#=GS A0A383YTC8_BALAS/923-1074   AC A0A383YTC8.1
#=GS A0A3B3Z1P0_9TELE/94-238     AC A0A3B3Z1P0.1
#=GS A0A1P8YP11_9NOCA/208-375    AC A0A1P8YP11.1
#=GS A0A0V0WGB7_9BILA/47-224     AC A0A0V0WGB7.1
#=GS A0A084QC88_STAC4/347-491    AC A0A084QC88.1
#=GS A0A1G7EXU4_9PROT/3-146      AC A0A1G7EXU4.1
#=GS B5DLW1_DROPS/271-421        AC B5DLW1.2
#=GS A0A3S0ZPX4_ELYCH/299-451    AC A0A3S0ZPX4.1
#=GS G1TR98_RABIT/36-200         AC G1TR98.1
#=GS A0A452SFA7_URSAM/116-260    AC A0A452SFA7.1
#=GS Q5Z0T4_NOCFA/29-186         AC Q5Z0T4.1
#=GS A0A0D3CKD6_BRAOL/138-284    AC A0A0D3CKD6.1
#=GS A0A3Q4MX80_NEOBR/167-311    AC A0A3Q4MX80.1
#=GS Y091_METJA/4-144            AC Q57556.1
#=GS Y091_METJA/4-144            DR PDB; 5HYA A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HXS A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDN A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 3V5S A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HXH A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HXC A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDH A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDF A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 3V5U A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDQ A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HXE A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HWX A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HXH B; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HWY A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDG A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5HXR A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDM A; 163-299;
#=GS Y091_METJA/4-144            DR PDB; 5JDL A; 163-299;
#=GS A0A1J9RYP3_9PEZI/295-439    AC A0A1J9RYP3.1
#=GS A0A218UHH7_9PASE/76-247     AC A0A218UHH7.1
#=GS A0A0D5YPR5_9FLAO/170-313    AC A0A0D5YPR5.1
#=GS D7EAY0_METEZ/3-144          AC D7EAY0.1
#=GS G2J549_PSEUL/212-355        AC G2J549.1
#=GS A0A2H3ZD77_PHODC/395-550    AC A0A2H3ZD77.1
#=GS A0A3Q2VIV1_HAPBU/103-246    AC A0A3Q2VIV1.1
#=GS K0KEV5_WICCF/396-545        AC K0KEV5.1
#=GS A0A1U8K5G1_GOSHI/420-575    AC A0A1U8K5G1.1
#=GS A0A1V4KB32_PATFA/334-486    AC A0A1V4KB32.1
#=GS A0A2H3L0I6_9CHLR/4-146      AC A0A2H3L0I6.1
#=GS A0A494TLC9_9SPHN/190-331    AC A0A494TLC9.1
#=GS D4AWI2_ARTBC/214-356        AC D4AWI2.1
#=GS A0A3B4X0F0_SERLL/99-270     AC A0A3B4X0F0.1
#=GS A8X6X6_CAEBR/580-730        AC A8X6X6.2
#=GS A0A0L0NB53_9HYPO/294-451    AC A0A0L0NB53.1
#=GS F0XQS0_GROCL/115-248        AC F0XQS0.1
#=GS A0A0D9Y537_9ORYZ/87-268     AC A0A0D9Y537.1
#=GS A0A177V2T7_9BASI/1405-1559  AC A0A177V2T7.1
#=GS A0A0K3C452_RHOTO/378-518    AC A0A0K3C452.1
#=GS A0A1Q8IRN4_9BURK/195-335    AC A0A1Q8IRN4.1
#=GS A0A094H1X1_9PEZI/936-1091   AC A0A094H1X1.1
#=GS A0A2K1QZP4_9PEZI/125-267    AC A0A2K1QZP4.1
#=GS A0A0B4DBL9_9FLAO/211-355    AC A0A0B4DBL9.1
#=GS A0A1S8TXI9_9CLOT/203-346    AC A0A1S8TXI9.1
#=GS W4Y4Z3_STRPU/585-736        AC W4Y4Z3.1
#=GS A7HVG0_PARL1/200-342        AC A7HVG0.1
#=GS A0A453CW98_AEGTS/284-429    AC A0A453CW98.1
#=GS A3TU12_PSEBH/173-316        AC A3TU12.1
#=GS A0A0E0MY08_ORYRU/273-418    AC A0A0E0MY08.1
#=GS A0A346NKC4_9ALTE/172-318    AC A0A346NKC4.1
#=GS A0A417PK28_9CLOT/165-307    AC A0A417PK28.1
#=GS A0A1V6MQ96_9ACTN/221-365    AC A0A1V6MQ96.1
#=GS S8BPR2_DACHA/115-278        AC S8BPR2.1
#=GS A0A1T4TWI1_9GAMM/3-145      AC A0A1T4TWI1.1
#=GS G1L049_AILME/468-620        AC G1L049.1
#=GS A0A1W1XUZ9_9DELT/3-145      AC A0A1W1XUZ9.1
#=GS W9WQM2_9EURO/944-1099       AC W9WQM2.1
#=GS A0A4D8ZIS2_SALSN/525-671    AC A0A4D8ZIS2.1
#=GS G7E7H1_MIXOS/112-254        AC G7E7H1.1
#=GS A0A1V4C2A6_9EURY/32-207     AC A0A1V4C2A6.1
#=GS A0A2R4MD08_9RHIZ/1-143      AC A0A2R4MD08.1
#=GS A0A2T0XQ07_9BACT/3-152      AC A0A2T0XQ07.1
#=GS A0KF88_AERHH/37-193         AC A0KF88.1
#=GS A0A1M5CHP3_9FLAO/1-144      AC A0A1M5CHP3.1
#=GS A0A284RLR6_9AGAR/629-777    AC A0A284RLR6.1
#=GS A0A2N0WYM8_9GAMM/6-148      AC A0A2N0WYM8.1
#=GS R6EX58_9BACE/3-153          AC R6EX58.1
#=GS A0A166ISV9_9GAMM/3-145      AC A0A166ISV9.1
#=GS A0A0A1T5H1_9HYPO/338-493    AC A0A0A1T5H1.1
#=GS A0A0N1J2Q5_FUSLA/578-723    AC A0A0N1J2Q5.1
#=GS A0A1X7S8T4_ZYMTR/206-348    AC A0A1X7S8T4.1
#=GS A0A2P6QA72_ROSCH/338-484    AC A0A2P6QA72.1
#=GS A0A1V9K779_9ACTN/221-365    AC A0A1V9K779.1
#=GS S7Q2N4_GLOTA/134-294        AC S7Q2N4.1
#=GS Q65MF6_BACLD/25-179         AC Q65MF6.1
#=GS A0A2T1C811_9CYAN/212-357    AC A0A2T1C811.1
#=GS M0CX08_9EURY/227-376        AC M0CX08.1
#=GS A0A182RU29_ANOFN/81-222     AC A0A182RU29.1
#=GS A0A0Q9W8Q0_DROVI/74-217     AC A0A0Q9W8Q0.1
#=GS A0A395GWT7_9EURO/238-384    AC A0A395GWT7.1
#=GS E6WVS2_PSEUU/171-313        AC E6WVS2.1
#=GS A0A3F3Q1G8_9EURO/78-239     AC A0A3F3Q1G8.1
#=GS S9S0L1_9RHOB/192-341        AC S9S0L1.1
#=GS A0A0D9NNY9_METAN/651-796    AC A0A0D9NNY9.1
#=GS A0A1Q5MT25_9ACTN/234-378    AC A0A1Q5MT25.1
#=GS A0A2T0RRM5_9RHOB/4-141      AC A0A2T0RRM5.1
#=GS A0A2C9JQA7_BIOGL/2-94       AC A0A2C9JQA7.1
#=GS A0A074TQA3_9RHOB/53-209     AC A0A074TQA3.1
#=GS A0A150X1G9_9BACT/170-314    AC A0A150X1G9.1
#=GS A0A2R6PV84_9APHY/105-279    AC A0A2R6PV84.1
#=GS A0A1B9I1W8_9TREE/454-600    AC A0A1B9I1W8.1
#=GS A0A0D1ZIK5_EXOME/221-388    AC A0A0D1ZIK5.1
#=GS A0A060W262_ONCMY/220-385    AC A0A060W262.1
#=GS A0A3B3D8J1_ORYME/776-942    AC A0A3B3D8J1.1
#=GS A0A091K8X8_EGRGA/1-142      AC A0A091K8X8.1
#=GS A0A2I2GCC1_9EURO/871-1025   AC A0A2I2GCC1.1
#=GS A0A1U7D2W0_9RHOB/9-157      AC A0A1U7D2W0.1
#=GS A0A2T7F1Q7_9POAL/282-427    AC A0A2T7F1Q7.1
#=GS A0A0K9XC19_9ACTN/221-365    AC A0A0K9XC19.1
#=GS B9S836_RICCO/74-228         AC B9S836.1
#=GS A0A383V739_TETOB/83-254     AC A0A383V739.1
#=GS A0A194UVL1_9PEZI/314-459    AC A0A194UVL1.1
#=GS A0A067DY21_CITSI/87-247     AC A0A067DY21.1
#=GS A0A1L8H0N1_XENLA/93-237     AC A0A1L8H0N1.1
#=GS NCL2_ORYSJ/421-567          AC Q6K3R5.2
#=GS A0A2K6KMG8_RHIBE/1-167      AC A0A2K6KMG8.1
#=GS H0VFZ2_CAVPO/74-245         AC H0VFZ2.2
#=GS A0A1V6NVB0_PENDC/912-1067   AC A0A1V6NVB0.1
#=GS A0A3Q7HFW8_SOLLC/102-261    AC A0A3Q7HFW8.1
#=GS V5WHL4_9SPIO/189-332        AC V5WHL4.1
#=GS A0A3A9A0U1_9BACT/173-315    AC A0A3A9A0U1.1
#=GS K7M288_SOYBN/558-704        AC K7M288.1
#=GS A0A176L9S9_9ACTN/32-189     AC A0A176L9S9.1
#=GS A0A2I4BZ40_9TELE/85-256     AC A0A2I4BZ40.1
#=GS A0A160DU90_9GAMM/31-188     AC A0A160DU90.1
#=GS A0A168NEZ1_ABSGL/231-376    AC A0A168NEZ1.1
#=GS A0A418NQ94_9SPHN/186-331    AC A0A418NQ94.1
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#=GS A0A3B4W9F1_SERLL/760-926    AC A0A3B4W9F1.1
#=GS A0A1U8CHY8_MESAU/103-246    AC A0A1U8CHY8.1
#=GS A0A1T4VCU9_9DELT/203-333    AC A0A1T4VCU9.1
#=GS N4V6P6_COLOR/9-154          AC N4V6P6.1
#=GS A0A427Y166_9TREE/677-828    AC A0A427Y166.1
#=GS A3JZM9_9RHOB/174-316        AC A3JZM9.1
#=GS A0A337SNP0_FELCA/274-425    AC A0A337SNP0.1
#=GS A0A0C4DL04_MAGP6/145-303    AC A0A0C4DL04.1
#=GS F9G5C3_FUSOF/15-159         AC F9G5C3.1
#=GS A0A3M7SUJ9_BRAPC/186-351    AC A0A3M7SUJ9.1
#=GS Q3SKM4_THIDA/1-161          AC Q3SKM4.1
#=GS A0A366S2D1_9HYPO/140-298    AC A0A366S2D1.1
#=GS A0A257ERM9_9PROT/41-192     AC A0A257ERM9.1
#=GS A0A340WFK9_LIPVE/77-248     AC A0A340WFK9.1
#=GS A0A0E0QZI5_ORYRU/210-366    AC A0A0E0QZI5.1
#=GS A0A2I2ZCF7_GORGO/910-1002   AC A0A2I2ZCF7.1
#=GS A0A3B3QTQ3_9TELE/72-243     AC A0A3B3QTQ3.1
#=GS A0A0A8JJJ5_BACSX/25-179     AC A0A0A8JJJ5.1
#=GS A0A3Q4GGP9_NEOBR/69-240     AC A0A3Q4GGP9.1
#=GS A0A3P7M5X7_LITSI/402-560