GenomeNet

Database: Pfam
Entry: Ntox17
LinkDB: Ntox17
Original site: Ntox17 
#=GF ID   Ntox17
#=GF AC   PF15524.7
#=GF DE   Novel toxin 17
#=GF PI   Toxin_45; Toxin_17;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   29.70 28.50;
#=GF NC   24.90 23.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029117;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted RNase toxin found in bacterial polymorphic toxin
#=GF CC   systems.  The toxin possesses a mostly all-beta fold and a
#=GF CC   conserved ExD motif and a histidine residue. In bacterial
#=GF CC   polymorphic toxin systems, the toxin is exported by the type 2,
#=GF CC   type 7 or TcdB/TcaC-type secretion system [1].
#=GF SQ   13
#=GS A0A317C8G2_9GAMM/64-139     AC A0A317C8G2.1
#=GS A0A197SVB2_9ACTN/1343-1435  AC A0A197SVB2.1
#=GS A0A077FK35_9RICK/407-500    AC A0A077FK35.1
#=GS A0A151YVJ0_9BACL/201-293    AC A0A151YVJ0.1
#=GS A0A1I4ZPH7_9ENTR/61-154     AC A0A1I4ZPH7.1
#=GS A0A0C4FDZ5_PUCT1/192-241    AC A0A0C4FDZ5.1
#=GS A0A433XU34_9BACL/1778-1870  AC A0A433XU34.1
#=GS A0A0G3BPW7_9BURK/1537-1638  AC A0A0G3BPW7.1
#=GS A0A100Y8T9_9ACTN/1095-1185  AC A0A100Y8T9.1
#=GS T0NGV8_9CLOT/80-172         AC T0NGV8.1
#=GS W2ENP4_9ACTN/514-605        AC W2ENP4.1
#=GS A0A1V4EW76_9BACL/2273-2363  AC A0A1V4EW76.1
#=GS A0A0A7S9I2_FRIPE/696-789    AC A0A0A7S9I2.1
A0A317C8G2_9GAMM/64-139                ......wlr------IYQKPLPCFGEFPFIP.PSNWRnFAAPI-K..GSQ.RGFLDESGNSWEWDR...----LHDNHWDVQHSS.KT----....-..------.-...------------gdytnvspegvil
A0A197SVB2_9ACTN/1343-1435             ....gvkgl------IKEAQLPTSGRIRFVP.SQDVN.VNSGLPR..GTR.KGYIDRFGNEWIKGP...SRTAGQPFEWDVQLSK.KGKAQL....G..WLSRDG.S...HLNVSLDGEITH.............
A0A077FK35_9RICK/407-500               ......ytq---TSRLKAEQLPREGKVRFIP.RDDWN.PNDPD-R..GPNgKGFKDKYGNIWVSGP...SRTKGQKFEWDVQLSD.KGRQMF....G..WASRDG.K...HINVSLDGKITH.............
A0A151YVJ0_9BACL/201-293               ........k-NITNPITKAQLPKKGKFRFIP.GKEVK.YDKKL--..---.GGYVDRFGNVWKKGPyhgDPNKDFDFEWDVQLSE.KGLKKW....G..QYTKNNkK...YINVTPDGEISH.............
A0A1I4ZPH7_9ENTR/61-154                .........WSTEGRIKYVELSTQGKIRFVP.DSNYS.PCNPLPR..GPN.NGYLDKFGNEWVKGS...SRTAGQAFEWDVQLSP.KSKAQP....G..WATRDG.S...HLNISLDGGITH.............
A0A0C4FDZ5_PUCT1/192-241               .........WSTKGRINYVQLPNEGKIRYVP.PEGYS.ASQPLPR..GPN.NGYIDKFGNEWVK--...----------------.------....-..------.-...------------.............
A0A433XU34_9BACL/1778-1870             ...gtktil-------KERMLPTTGKIRYIP.PAYWT.PSQPLPR..TGN.GGYIDKFGNVWSKGP...SRTAGQPFEWDVNLSN.TGKAQL....E..WASRDG.S...HLNVSLDGKITH.............
A0A0G3BPW7_9BURK/1537-1638             ......skq----QRLKEAGLPRAGTYRFLP.REGYN.PCSPLPK..GES.GGYLDRFGNEWVKGPyhgDPKLPFEYEWDVQLSK.RGEAAWnarrGasKAQGGG.Y...YVNVRPDGMKSH.............
A0A100Y8T9_9ACTN/1095-1185             ryvqaadkf----------GLPTNGPVPFVP.RKDWD.VKRPQIR..G--.GGFEDKYGNIWTRAK...----DGKDEWDVQIPKgKGFETF....A..GSKNQG.KdysHANISRDGKVTH.............
T0NGV8_9CLOT/80-172                    ...vgkkti------IKSKGLPTKGKIRYVP.PKNWT.TSQPLPR..SG-.AGFTDRFGNVWTKGP...SRTAGQAFEWDVQLSK.SGKSQL....G..HFSRDG.S...HLNISLDGKITH.............
W2ENP4_9ACTN/514-605                   ....waeka-------EKLNLPTDGPVPFVP.PKNWD.VRNPQKDvlNGR.EGFVDAYGNVWHKGP...GR-GGQPYEWDVQVR-.-GQGGI....S..VLTGDG.S...HLNVEW------gtgrvth......
A0A1V4EW76_9BACL/2273-2363             ..lrgivka---------KGLPTDGRFHFVAdGNKVE.FNRSK--..---.GGYVDRYGNVWVKGPyhgDPKLGFTYEWDVQLSA.SGKNAW....G..KFANGK.G...YINVRPDGGLSH.............
A0A0A7S9I2_FRIPE/696-789               .........WTIAQRLKYAKLPTTGKIRFVP.RKRYK.PNDPLER..GPN.NGYVDNFNNEWVKGP...SRTAGQEFEWDVQLSK.LGNKQL....G..WASRDG.K...HLNVSLDGKITH.............
#=GC seq_cons                          .......hh......lctttLPTpG+lRFVP.scsas.sspPL.R..Gsp.sGYlD+FGN.WsKGP...s.ptGpsaEWDVQLSp.pGptth....G..hhopsG.p...HlNVohDGtloH.............
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