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Database: Pfam
Entry: Ntox30
LinkDB: Ntox30
Original site: Ntox30 
#=GF ID   Ntox30
#=GF AC   PF15532.7
#=GF DE   Bacterial toxin 30
#=GF PI   Toxin_53; Toxin_30;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.40 27.40;
#=GF NC   24.20 24.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029111;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted RNase toxin found in bacterial polymorphic toxin
#=GF CC   systems.  The toxin possesses an all-beta fold and two conserved
#=GF CC   histidines present in an RxH and THIP motif. The domain
#=GF CC   additionally has a highly conserved arginine residue. In
#=GF CC   bacterial polymorphic toxin systems, the toxin is usually
#=GF CC   exported by the type 2, type 6 or type 7 secretion systems [1].
#=GF SQ   22
#=GS X2HD58_9NEIS/56-166         AC X2HD58.1
#=GS D9VS65_9ACTN/1-78           AC D9VS65.1
#=GS A0A1C4JWI3_9ACTN/1448-1551  AC A0A1C4JWI3.1
#=GS B5HCD7_STRE2/1315-1417      AC B5HCD7.2
#=GS U2RNR2_9ACTN/202-283        AC U2RNR2.1
#=GS A0A384I177_9ACTN/89-192     AC A0A384I177.1
#=GS A0A0N1KCH6_9ACTN/1412-1515  AC A0A0N1KCH6.1
#=GS A0A1E5KX71_9ENTE/1-101      AC A0A1E5KX71.1
#=GS C7Q9A7_CATAD/351-460        AC C7Q9A7.1
#=GS A0A2T7BMS2_9BACT/585-687    AC A0A2T7BMS2.1
#=GS A0A0Q4R3G4_9BACL/819-922    AC A0A0Q4R3G4.1
#=GS W7CDV5_9LIST/282-384        AC W7CDV5.1
#=GS F2NYM6_TRES6/415-516        AC F2NYM6.1
#=GS A0A1M7N2B1_9ACTN/1482-1584  AC A0A1M7N2B1.1
#=GS A0A1X7N0N1_9RHIZ/261-347    AC A0A1X7N0N1.1
#=GS Q0RWZ5_RHOJR/2541-2646      AC Q0RWZ5.1
#=GS A0A3L8JA57_9ACTN/1559-1661  AC A0A3L8JA57.1
#=GS A0A109LQR9_9SPHN/423-510    AC A0A109LQR9.1
#=GS A0A090ZIW9_PAEMA/947-1054   AC A0A090ZIW9.1
#=GS A0A1K1SDJ2_9BACT/2796-2889  AC A0A1K1SDJ2.1
#=GS F2JHT4_CELLD/472-574        AC F2JHT4.1
#=GS A0A428X835_9ACTN/88-190     AC A0A428X835.1
X2HD58_9NEIS/56-166                    gqikyndvtkwanqggisnqwmsssq-----------------.---.FPSGGFKYQTNS..........--NGIT....YSVHGHGTNPNA..VArypSSNAAKGPTASITTRp.........tgGAH--...SAQTNTL.....SNGTKVNSRG.....R....DDVQMNQSHIPL-i..................
D9VS65_9ACTN/1-78                      ..........................-----------------.---.-----MEYHWTD..........AVTGNS....ARLRIHDIDGTA..PA...GSHAATGDSYRLSIG............GKYQD...EAGRLHH.....RNVHNERSPH.....Y....DPDAANATHIPWP...................
A0A1C4JWI3_9ACTN/1448-1551             ..........................NPLDIVPGDAEKRVLTPdANG.GAQKGVEYKWKD..........PETGNT....VRLRVHDKDGTA..PA...GSNAANGDVYRISIG............GKYQD...EAGSLYH.....RQVHNPNSPH.....H....NPDAANGTHIPWP...................
B5HCD7_STRE2/1315-1417                 ..........................NPLSIIPKDAVQEPWKP.IPG.GVEHGIKWKWTD..........DVTGKT....VRMRVHGPDLGP..HA...GPNASSGPIYRIQIG............HQFQD...EAGKLYH.....AQIGNVNSPN.....Y....NEAAINDTHIPWP...................
U2RNR2_9ACTN/202-283                   ............hqwadqqglpntwr-----------------.---.-----------EdpvnfptggeRADNGT....YHVHMHGPNPRA..PQ...GSNSSNGPTVSIKGP............NGW--...-------.....----------.....-....-------------fgtdeawrprnnnneship
A0A384I177_9ACTN/89-192                ..........................NPLDIVPGDAEMRTLKPdPNG.GAQKGVEYKWQD..........SETGNT....VRLRVHDKDGTA..PP...GSNAANGGIYRLSIG............GRYQD...EAGNLYH.....RQVHNPNSPN.....Y....NDNAAHATHIPWP...................
A0A0N1KCH6_9ACTN/1412-1515             ..........................NPLDIVPPNAEMRHLTPdPNG.GAQVGVEYRWPD..........PETGKT....ARLRVHGPDGKA..PA...GSHAAEGDIYRVQVG............NQYQD...IDGNLYH.....RNVHKEASPH.....Y....DPTAANRTHIPWP...................
A0A1E5KX71_9ENTE/1-101                 .........................m---SRIPKEANKRVLTP.QPG.KVTEGFEYTWKT..........-SEGAK....MTVRVHGPDASA..PA...GSNAANDWVVRVQQG............KKYLD..pISGEFQP.....PGISRPNSEF.....Y....NEELINNTNIPIQ...................
C7Q9A7_CATAD/351-460                   ..........................DPSELVPPYARQRPWTPaAPGqGAEDGVEWIWKErd.....angDEIGPT....IRLRVHSADPTA..PA...GSNAANGPIYRIQHG............AKYQD...ADGNLHP.....QGIHNKDSPN.....Y....DEDAINDTHIPWP...................
A0A2T7BMS2_9BACT/585-687               .........silaralkrqglpklpg-----------------.---.----NFKEKWAE..........--NGYD....YEVRSRGADNKA..PA...GSNSAHGQTFRVARRlqgknengqgngW----...----EYA.....DDNNNWYSETqlksgN....NPQAANDTHIPV-n..................
A0A0Q4R3G4_9BACL/819-922               ..........................EILSRIPTDAKRRELFP.IEG.KVMEGFEYKWVE..........--DGQT....IRVRVHGPDSSPdiPA...GSNAANGWIVRIQKG............KKYFD..pVTGEYQP.....PGISNPASEF.....Y....NEDLINRTHIPIK...................
W7CDV5_9LIST/282-384                   ..........................DILSRIPKDANKRVLTP.QPG.KVTEGFEYTWKA..........-SDGTK....MTVRVHGPDASA..PA...GSNSADGWIVRVQKG............KKYLD..pVAGEFQP.....PGISRPNSEF.....Y....NEDLINSTHIPIQ...................
F2NYM6_TRES6/415-516                   ..........................EVLTRIPKNATRRELIP.EAG.KVTEGFEYKWIT..........--NGKT....YRARIHGIDGSA..PK...GSNASKGWVLRIQEG............KKYLDpitLEYQRPG.....--ITNIDSPY.....Y....NEELANRTHIPIK...................
A0A1M7N2B1_9ACTN/1482-1584             ..........................DPMSIVPDDAKIRELTP.HSGgGSQYGLEYSWKN..........-DAGQT....VRLRIHGPDGTA..PV...GSNSASGETYRIQIG............RQYQD...EAGNLYH.....HQSHNPNSPN.....Y....NPNAANATHIPWP...................
A0A1X7N0N1_9RHIZ/261-347               .................qirklipan------------RELPF.TKSqRIDEGYKYRFFL..........--KGQR....VEIKWHSPDRGA..PV...GSNSRKMWTAQVQIG............GKYLG...SDGKLYR.....NAKQNI----.....-....-------------thiply.............
Q0RWZ5_RHOJR/2541-2646                 ..............apgradlilqap---------------APtGARvNVSGGMMVNEHTvp.....aasTAKGATgivaTRIRVHTADPTA..PE...GSNSASGNTVSITQGgg........arRMLPD...-------.....--GSWVQTSR.....A....TGEQMNLSHIPIH...................
A0A3L8JA57_9ACTN/1559-1661             ..........................DPMSVVPDHAGIRELTPdPNG.GAQYGLEYKWMD..........-SQERT....VRLRIHGPDGNA..PA...GSNAAMGDSYRIQFG............GKYQD...DLGNLYP.....RNVHNENSPH.....Y....NPDAANATHIPWP...................
A0A109LQR9_9SPHN/423-510               ..........eiisrvpsdwtmlpqq-----------------.---.---RGMGIRFID..........--DTGA....ERLRLHGPSARA..PE...GSNAASGWTARVHVPg.........tsNQYYD...NLGNIVG.....AR--------.....-....-------------nndghipvygnan......
A0A090ZIW9_PAEMA/947-1054              .........................d-FITRIPANAKQIPWRQ.VPG.GAKDGVKFRWVD..........-GTGKT....WDVRAHSIDPTA..PP...GSNAAKGWIYRVEVKqvn......pkwKWTMD...SSGNFHK.....ENVLRESSPY.....Y....NESIANETHIPF-t..................
A0A1K1SDJ2_9BACT/2796-2889             .................qglvylpek-----------------.---.-----FKEKWSE..........--GGYD....YEVRIHPKQENA..PE...GSNSRNGTTYRVARR............LQGSD...SNGQGFGweyvdDKNNWYKERD.....LktgdNKQAANDTHIPLK...................
F2JHT4_CELLD/472-574                   ..........................DILDRIPDDATLRELTP.VKG.GATEGFEFKWIQ..........--DNQT....YRVRVHNIDPGA..PV...GSNASQGWIVRIQRG............RQYYDy.tIEGFQPA.....KYTNNPNGEF.....F....DSTITNNTHIPIK...................
A0A428X835_9ACTN/88-190                ..........................DPMSIVPDNASVRELTP.HPNgGSQYGLEFKWTN..........-DAGKT....VRLRIHGPDGTA..PA...GSNSATGEAYRVQIG............RQYQD...EAGNLFH.....HQSHNPNSPN.....C....NPDAANATHIPWP...................
#=GC seq_cons                          .............................phlP..A..c.hhP...u.tsptGhca+Whs............sGpT....hRlRlHusDssA..Ps...GSNAAsG.shRlphG............tpY.D....sGphht.....pthpp.sS.......a....s.shhNtTHIPh....................
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