GenomeNet

Database: Pfam
Entry: Orf78
LinkDB: Orf78
Original site: Orf78 
#=GF ID   Orf78
#=GF AC   PF06024.12
#=GF DE   Orf78 (ac78)
#=GF PI   DUF912;
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_8809 (release 9.0)
#=GF GA   28.00 28.00;
#=GF TC   28.20 28.20;
#=GF NC   27.90 27.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   23698311
#=GF RT   The Autographa californica multiple nucleopolyhedrovirus Orf78
#=GF RT   is essential for budded virus production and general occlusion
#=GF RT   body formation.
#=GF RA   Tao XY, Choi JY, Kim WJ, Lee JH, Liu Q, Kim SE, An SB, Lee SH,
#=GF RA   Woo SD, Jin BR, Je YH;
#=GF RL   J Virol. 2013;87:8441-8450.
#=GF RN   [2]
#=GF RM   25087880
#=GF RT   Disruption of the baculovirus core gene ac78 results in
#=GF RT   decreased production of multiple nucleocapsid-enveloped
#=GF RT   occlusion-derived virions and the failure of primary infection
#=GF RT   in vivo.
#=GF RA   Li SN, Wang JY, Yuan MJ, Yang K;
#=GF RL   Virus Res. 2014;191:70-82.
#=GF DR   INTERPRO; IPR009261;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Family members include Autographa californica nuclear
#=GF CC   polyhedrosis virus (AcMNPV), AC78 or Orf78. AC78 is a late gene
#=GF CC   in the viral life cycle and encodes an envelope structural
#=GF CC   protein that plays an essential role in embedding the
#=GF CC   occlusion-derived virus (ODV) in the occlusion body [1].
#=GF CC   Although AC78 is not essential for budding virus formation or
#=GF CC   nucleocapsid assembly and ODV formation, number are
#=GF CC   significantly reduced if the gene is knocked-out [2].
#=GF SQ   51
#=GS Q77K68_9ABAC/3-110        AC Q77K68.1
#=GS L0CJS3_9ABAC/3-105        AC L0CJS3.1
#=GS Q6QXL6_GVAS/4-93          AC Q6QXL6.1
#=GS A0A109WZD6_9BBAC/16-102   AC A0A109WZD6.1
#=GS Q91BF0_NPVST/3-114        AC Q91BF0.1
#=GS Q8B9H6_NPVR1/3-104        AC Q8B9H6.1
#=GS A1YJ73_NPVSF/3-114        AC A1YJ73.1
#=GS Q2NNZ9_NPVHC/3-102        AC Q2NNZ9.1
#=GS D4N2C0_9ABAC/16-110       AC D4N2C0.1
#=GS A0A024WFD9_PLAFA/4-8      AC A0A024WFD9.1
#=GS Q7TLS4_NPVCF/3-101        AC Q7TLS4.1
#=GS A0A162GW05_9BBAC/5-106    AC A0A162GW05.1
#=GS W0UXW2_9ABAC/3-128        AC W0UXW2.1
#=GS Q9Q0A9_NPVAG/3-104        AC Q9Q0A9.1
#=GS D2J4Q6_9BBAC/8-94         AC D2J4Q6.1
#=GS Q6JPC5_NPVNC/1-92         AC Q6JPC5.1
#=GS Q80LN4_NPVAH/3-102        AC Q80LN4.1
#=GS Y078_NPVOP/3-100          AC O10331.1
#=GS V9XSN9_9ABAC/3-102        AC V9XSN9.1
#=GS A0A063BVC7_9HYPO/254-344  AC A0A063BVC7.1
#=GS A1YRC3_9ABAC/3-101        AC A1YRC3.1
#=GS B6D612_9ABAC/3-120        AC B6D612.1
#=GS A0A0C5B372_9BBAC/4-99     AC A0A0C5B372.1
#=GS A0A1S5YE07_9BBAC/4-97     AC A0A1S5YE07.1
#=GS A0EYW5_9ABAC/3-110        AC A0EYW5.1
#=GS AC78_NPVAC/3-104          AC Q06693.1
#=GS A0A1I3UV40_9GAMM/1-63     AC A0A1I3UV40.1
#=GS A0A0B5E865_9ABAC/3-117    AC A0A0B5E865.1
#=GS A0A172WZE3_9ABAC/3-106    AC A0A172WZE3.1
#=GS A5IZU8_9BBAC/6-90         AC A5IZU8.1
#=GS I3XMB3_NPVMB/42-149       AC I3XMB3.1
#=GS A0A162GUT3_9BACU/3-106    AC A0A162GUT3.1
#=GS A0A097P902_9ABAC/3-110    AC A0A097P902.1
#=GS Q1HH23_NPVAP/3-98         AC Q1HH23.1
#=GS S5N417_9ABAC/3-103        AC S5N417.1
#=GS Q287I0_NPVAS/3-123        AC Q287I0.1
#=GS B0FDT9_9ABAC/1-115        AC B0FDT9.1
#=GS A0A0M3WNH0_9BACU/3-116    AC A0A0M3WNH0.1
#=GS W5VKG7_NPVBS/3-106        AC W5VKG7.1
#=GS A0A183MAX1_9TREM/4-80     AC A0A183MAX1.1
#=GS B6S6Z5_GVPU/5-105         AC B6S6Z5.1
#=GS Q9YMP0_NPVLD/10-113       AC Q9YMP0.1
#=GS A0A0B5A1C8_9ABAC/3-122    AC A0A0B5A1C8.1
#=GS Q0N429_9ABAC/3-106        AC Q0N429.1
#=GS C3TWX8_9ABAC/3-108        AC C3TWX8.1
#=GS B7SVW3_9ABAC/3-121        AC B7SVW3.1
#=GS P89281_GVXN/5-102         AC P89281.1
#=GS Q0IL29_NPVLS/3-98         AC Q0IL29.1
#=GS Q4KT03_9ABAC/3-120        AC Q4KT03.1
#=GS Q91GI3_NPVEP/3-102        AC Q91GI3.1
#=GS A0A0E3Z7F1_9ABAC/3-133    AC A0A0E3Z7F1.1
Q77K68_9ABAC/3-110                   ..............LDIPYDRLGVND.KVDYIPLKLAISDFn..............vDAADLSNNTDDSSTKSI.LGHNDLTSYRSNy........................qkRNNSTWIGNILLISLLAVFCVMVLL...YA...LY...YFVILRERR.KSIV...R.QPYYV.............
L0CJS3_9ABAC/3-105                   ..............LDVPYYRLGNHE.KVEYIPLKLALSD-................DVANEPQQQQFDETISK.MPLNDMVAYDNT...........................-TSNVSMGIIILISIVAFVALFLLL...YV...IY...YFVILRDQQ.YSDN...I.-----dtdspfv......
Q6QXL6_GVAS/4-93                     ..............LHIPFEKLKKVE.NLEGIPLKLAHAN-................---NNESP------QSL.YSKSDGENNVSN...........................---AKNEPLNIWFYAIGFIVVIVIV...FV...IV...YIVVSRLNK.SKHL...-.NEEY-ip...........
A0A109WZD6_9BBAC/16-102              .........dlitk---------SNV.KVEPIPLKLAHNN-................NNTTTAN----------.NSNNEFKNTNND...........................-TNNFTVSTIMWITLSCIIFMLVVV...FL...VS...YFIFNNNTE.DYDS...-.-----fneeyg.......
Q91BF0_NPVST/3-114                   ..............LDVPYDRLGITNeKVEYIPLKLAINV-................-NSDSDRGGNGGDVESI.AQNVKSTAIGFDaanq...................sapsSVVKNANMFNMMTGVIVVLCVLIVV...FA...LL...YFFLLREGR.RR--...-.-----rptslttpar...
Q8B9H6_NPVR1/3-104                   ..............LDVPYYRLGNHE.KVEYIPLKLALND-................--DIASEPQQFSEPVHK.MPINDMVGYDNT...........................-TSNVSAGIIILISVVAFIALFLLL...YV...IY...YFVILREQQ.QYSD...-.-----sidtdspfv....
A1YJ73_NPVSF/3-114                   ..............LDVPYERLGTAT.KVDYIPLKLALTDLp..............sENTSDNNDDNQKNNNTQ.NPKIDINQSNANnyn....................qhqsVRSKQQFYDILVLGMLTVFCILVLL...YA...IY...YFVILRDRQ.KSNT...I.RPSYM.............
Q2NNZ9_NPVHC/3-102                   ..............LDVPYYRLGNHE.RVEYIPLKLALND-................DAPPDNSHEYADSM---.-EHKMDGEMQTR...........................-ANQMSTGLIMFISLIAFVALFLLL...YV...IY...YFVILREQP.QYSNdidN.DPSF-l............
D4N2C0_9ABAC/16-110                  ..............LDVPYEQLNEQQfKVLYIPLKLALRD-................--DDDAAP--AKDAFVL.EPPRY-TDAEAR...........................---AHASGNALVMALLSVFCIVVLI...YA...IY...YFVILRERH.NLFV...N.QPKFI.............
A0A024WFD9_PLAFA/4-8                 ............pd------------.--------------................-----------------.------------...........................-------------------------...--...--...---------.----...-.---F-qa...........
Q7TLS4_NPVCF/3-101                   ..............LDVPYYRLGNHE.RVDYIPLKLALSD-................DAPAPSAHEAEPA----.-AYKVAGEMDAP...........................-ANQMSAGLIVLISLIAFVALFLLL...YV...IY...YFVILRDRP.EYSNdidD.DPSF-v............
A0A162GW05_9BBAC/5-106               ..............LEIPFERFNISG.VVEAIPLKLAYSK-................--ESDNAPDSKSPVVPS.AQAVYGKNEEK-...........................-XSMQSDSSNVWFIAMACISVLVVI...LL...IS...YYIVNVLRT.N---...-.-----ggsykdfsedeey
W0UXW2_9ABAC/3-128                   ..............LDVPYERLGTAT.KVDYIPLKLALTDLpennissssssvddydNNDKNKTLSSAATAKNQ.RPKVDIDLTDRNlqlr...................qpsaDLSKQQFYNSLVLGLLTFFCVLVLL...YA...IF...YFVILRDRQ.KSIV...-.KPSYM.............
Q9Q0A9_NPVAG/3-104                   ..............LDVPYYRLGNHE.RVEYIPLKLALND-................DAPVNNNN----DDTAV.YEYSDVHKGETR...........................-TGQMSAGLIVLISLVAFVALFLLL...YV...IY...YFVILREEP.QYSS...-.-----dtidnsdpsfl..
D2J4Q6_9BBAC/8-94                    ..........isll---------RNT.YVEPIALKLAHIN-................NNSNNNNNHDQNES---.---NTVVASNE-...........................----DNAKPAMWLIIASGVFILIVV...LL...VS...YFIVSRING.RYRN...-.-----dfdeeny......
Q6JPC5_NPVNC/1-92                    .............m-NIDYNKISDDV.SVKTYPLKVNIPET................IATKNLSPRETTDSSTD.DATSNNDTNTTN...........................--FVWQLLSICIVGLLIIVGIIVLL...YF...L-...---------.----...-.-----ssrddgqaeii..
Q80LN4_NPVAH/3-102                   ..............FDIPYDKLSSNA.KVDYIPLKLALSDI................DENGHTKNNSENDINKN.YLLNNHIDNGI-...........................--TEKTNINIIIVSLAVVLSMCIIF...FI...IY...YFVILRRDR.YSAT...I.NPNV-v............
Y078_NPVOP/3-100                     ..............LDVPYYRLGAHE.RVEYIPLKLALND-................DAPPPAAHEYAE-----.--ARAAGGEAAP...........................PAEQWSAGVIVLIGLVAFVALFLLL...YV...IY...YFVILRDQP.QYSD...-.-----didndppfa....
V9XSN9_9ABAC/3-102                   ..............LDVPYYRLGNHE.RVEYIPLKLALSD-................DAPAPSAHEQAE----P.VAYKMADEMEAP...........................-AGQMSAGLIVLISLVAFVALFLLL...YV...IY...YFVILRDRP.EYSNdidD.DPSF-v............
A0A063BVC7_9HYPO/254-344             platsslltqplqq------------.--------------................-QQQQQQLQQLQQQQKQ.QQQQQQQQQQQQ...........................QQQQQQQQHVVVVVVVVVVVVVVVV...VV...VV...VVVVVEQQAaQSQV...Q.Q----ppcv.........
A1YRC3_9ABAC/3-101                   ..............LDVPYYRLGSHE.KVEYIPLKLALND-................-----DETANEPQQFNE.PPKNDMMGYDNA...........................-TSNMSAGIIILISVVAFVALFLLL...YV...IY...YFVILREQQ.QYLD...-.-----nidtnspfv....
B6D612_9ABAC/3-120                   ..............LDVPYERLGATT.KVDYIPLKLALNDLtdngvd....gggidkKTDPSKNRGDGEDKPKI.DINVRASRETPQaq.......................epPATKQQMYDALVVGMLTFFCILVLL...YA...IY...YFVILRDRQ.KSIV...-.RPSYM.............
A0A0C5B372_9BBAC/4-99                ..............LDIPFERLNLPD.VVEAIPLKLAYND-................DKQQQEQQ------DPV.TPSAQAVYGADN...........................KETVPPTDTNVWFIALTCITVLVVI...LL...IS...YYIVVSLRT.QNFV...E.DDEY-e............
A0A1S5YE07_9BBAC/4-97                ..............LDIPLERWSVPD.VVDAIPLKLAYTS-................-----SKDTTPPSAQAV.YNSKDDDAVSPP...........................---PATTDTNVWFIAFACITVLAIV...LL...IS...YYIVSALRI.----...-.-----ddtaeprdld...
A0EYW5_9ABAC/3-110                   ..............FEIPYERLGVKN.IVDYIPLKLALNDTde............skNYSASNSAAGAKNDNDN.LFYNNITSGRGN...........................--EQRGSEHIILITLLSIFCIIVILyivYA...IY...FFIILRDEQ.KSIA...P.QP---vsf..........
AC78_NPVAC/3-104                     ..............LDVPYYRLGNHE.KVEYIPLKLALND-................--DTASEPQQFSEPVHK.MPINDMVGYDNT...........................-TSNVSAGIIILISVVAFIALFLLL...YV...IY...YFVILREQQ.QYSD...-.-----sidtdspfv....
A0A1I3UV40_9GAMM/1-63                ..........msts------------.--------------................-----------------.-EKVKLPSTQTS...........................-SNKKKKRRAVILSLTSLFLILAIL...YA...IY...WFLVLRHHQ.ETD-...-.-----nayvagnq.....
A0A0B5E865_9ABAC/3-117               ..............LNVPYERLVATA.KVDYIPLKLALNDLyddggg...ggndsnnAKQASNEPKIDINTPPM.TGYGA------Ttta.....................aamPLQQKQMYDALVLGMLTFFCILVLL...YA...IY...YFVILRDSQ.NPPL...-.RPSY-i............
A0A172WZE3_9ABAC/3-106               ..............MDVPYYRLGSHE.KVEYIPLKLALSD-................DEQQQHQHQHQQQQ-HA.YGENDKIMMQTGem.......................ntAANNMSAGIIILISLVAFVALFVLL...YV...IY...YFVILREQQ.QYSD...N.-----snig.........
A5IZU8_9BBAC/6-90                    .............v-QVPFEKLSNTD.ALDAIPLKLAYTK-................----NDAP------QSF.YANESSDSPNAD...........................--------NNIWIVIICSITILALI...II...IS...YYIITTLYD.YYSV...E.D----efeye........
I3XMB3_NPVMB/42-149                  ..............LDIPYERLSPTL.TVKYIPLKLALNDIp..............dTSNGETANNKNSNDSAT.APKVNITVPEKRny......................dtnVASPKQMYDVLVLGMLTVFCILVLL...YA...IY...YFVILRDRQ.KPT-...-.-----epril........
A0A162GUT3_9BACU/3-106               .............f-NLPYKNFTINN.SVEYIPLKLVLNK-................DSSNDTKMSSNDTSNRT.LLMNESDNLYYE...........................KTILKLKFDILILYCVIVVCVTLVL...YF...IL...YYVILRERR.NNFV...-.-----girqnnly.....
A0A097P902_9ABAC/3-110               ..............LDVPYERLGTKN.SVEYIPLKLALNDF................NDKPNDNPSLQNGNISLpQQTNQMLQSEFNnf.......................nyNTNSQNIANIMLVTLLTVFCVIVLL...YA...IY...YFILLRDRR.QTFA...R.QRNFI.............
Q1HH23_NPVAP/3-98                    ..............LEVPYYRLGSHE.RVEYIPLKLALND-................EAPAADAA--------A.YDYGEASKADAP...........................-ANQAPVGLIVLISLVAFVALFLLL...YV...IY...YFLILRERP.QYSDdaeN.-----dpafv........
S5N417_9ABAC/3-103                   ..............LDMPYYRLGNHE.RVEYIPLKLALSD-................DAPTPTT---DEHAEPM.TAYKMTNEMEAP...........................-AGQMSAALIVLISLVAFVALFLLL...YV...IY...YFVILRDRP.EYSDdidN.DPSF-v............
Q287I0_NPVAS/3-123                   ..............LDVPYERLGPAT.KVDYIPLKLALDDLpdtdna....aknknnNNNNNNNNNDDTNSFRA.SPKVDIAVDKWTaqr....................eseaPSEKQQMYDALVVGMLTFFCILVLL...YA...IY...YFVILRDRQ.KSII...-.QPSYM.............
B0FDT9_9ABAC/1-115                   ..............MDVPYERLGIKP.PINYIPMKMAINDVggn..........avsS------KSRQGEQNLA.ATDTNFDDYARFingr..................gdgfeEGVLYNNTNAILIALVSVACVLVIF...YV...IYiiyISIILRERQ.SKIA...A.QQKF-f............
A0A0M3WNH0_9BACU/3-116               ..............FDIPYERFNNKN.KVEYIPLKLALND-................ENTDNEKGDQHSSSPSL.SSTSLFNNGELQnqqmn................vgdhqyNYFEKRMVDILMLSLLTFFCVLVLL...YA...VY...YFVILRDRQ.DTLM...SvQPNF-f............
W5VKG7_NPVBS/3-106                   ..............LDVPYERLGVKN.TVEYIPLKLALNDV................DNDNKNTASNEKRLL--.FDYNNGDTVQLNp........................icQNSSDHVANVLLVTLLTIFCIIVLL...YA...IY...YFVLIRDRR.HTIA...R.QRNF-l............
A0A183MAX1_9TREM/4-80                ...rrehllesnvt------------.--------------................----------K-ATNNN.NNHSNYLQNDEI...........................EFEMFHLTNNLLIILLSVLCIIIIL...LL...LI...YIVYRRLRH.HQHH...H.DSQY-f............
B6S6Z5_GVPU/5-105                    ..............LEIPFERFTIPD.VVDAIPLKLAYSK-................ETDDDMKHN---NKSPV.VPSAQAVYGNRD...........................EKSTQSDTTNVWFIALACITVLVVI...ML...IS...YYIVSVLRR.NNAP...-.-----lrdyeddd.....
Q9YMP0_NPVLD/10-113                  ..............LDVPYEQLNERPsKVMYIPLKLALRD-................---DDDAASAAAETGGA.APKNALVLEPPRht.......................daAARPRAGADVLVMALLSVFCIVVLV...YA...IY...YFVILRERR.KLFV...N.QPKFI.............
A0A0B5A1C8_9ABAC/3-122               ..............LEVPYERMSLNQkRVEYIPLKLAVNDIdengyk....kpkqktVN--------------D.ADDNEIKKIRTSptllsndig.........gntnyiayaNTEKTGVLNVVLLALLSIFCVLVIL...YA...IY...YFVIIRERE.KRIV...K.PPYF-i............
Q0N429_9ABAC/3-106                   ..............LEIPYERLSDKT.KVEYIPLKLALNDV................DTDTATVAIQGNDRAVV.GGHQELRELTNG...........................AYIAANTTNLLLIGLLSLVCVIILL...YA...IF...YFVILRERR.QTSL...N.-----yrqspl.......
C3TWX8_9ABAC/3-108                   ..............LEVPYERLGVNA.TVNFIPLKVDVNDV................VDNRSGGSQTPAETFES.FANVHNVNDNYHs.........................lVYQNSNSANAMLIALMSLFCIIVIV...YVaysIY...FFIILRDRE.SDRQ...-.-----qkff.........
B7SVW3_9ABAC/3-121                   ..............LDVPYERLGTST.KVDYIPLKLALTDLpetnggggngggenegK----NNDGTKNDQPKI.DITDRAKSQQTTtt......................ttsVQSKQQFYDALVLGLLTFFCILVLL...YA...IY...YFVILRDRQ.KSTI...-.KPSYM.............
P89281_GVXN/5-102                    ..............LDIPFDRLTIPD.AVDAIPLKLAYSK-................ESDDNNKPPVVPSAQAV.YGSREEKSAQSD...........................-------MSNVWFIALACITVLVVI...ML...IS...YYIVSVLRT.NNAP...-.-----lrdyeddef....
Q0IL29_NPVLS/3-98                    ..............LDIPYDRLGTSD.KVDYIPMKLAVNDA................--ANNDKS----KT-NA.LITSDDQQQQQQ...........................DEQPALKMNCFLMAFVLIVLIVAIL...YI...LY...YFFILRDRR.YHRR...G.RSSY-r............
Q4KT03_9ABAC/3-120                   ..............LEVPYERMSLNQkKVEYIPLKLAVNDIdengy.....kkpkqkTNDTEDDGINKTRPSSS.LLLNDIGNTNYTa........................yaNAAEGGILNVVLMALLSIFCVLVIL...YA...IY...YFVIIRERE.KRIV...K.PPYF-i............
Q91GI3_NPVEP/3-102                   ..............LDVPYYRLGNHE.RVEYIPLKLALND-................DTPASDAPAYEYND---.-DYAQKVTNDAP...........................-VNQMSAGLIVLISLVAFVALFLLL...YV...IY...YFVILREQP.QYSEdidN.DPSF-l............
A0A0E3Z7F1_9ABAC/3-133               ..............LDIPYELLGANNqNVEYIPLKFALKD-................ENNRSNVQ-QAQNKNNG.NNNDGVYNYDADhvddvaaqaynffnkfqdnnvrnaanfVSRNDKSLNCIIVAMLSVFCAIVLL...YA...IY...FFVILRDTK.YNTF...N.R----qqtkff.......
#=GC seq_cons                        ..............LDlPYcRLuspp.pV-YIPLKLAlsD.................ptsssspsttttpt.t..hspsphsp.pss............................tpptshtshlllulluhhsllllL...Ys...IY...YFVILR-cp.p..s.......................
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