GenomeNet

Database: Pfam
Entry: P3A
LinkDB: P3A
Original site: P3A 
#=GF ID   P3A
#=GF AC   PF08727.15
#=GF DE   Poliovirus 3A protein like
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF SE   pdb_1ng7
#=GF GA   22.30 22.30;
#=GF TC   22.70 27.30;
#=GF NC   22.20 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12823963
#=GF RT   Towards an understanding of the poliovirus replication complex:
#=GF RT   the solution structure of the soluble domain of the poliovirus
#=GF RT   3A protein. 
#=GF RA   Strauss DM, Glustrom LW, Wuttke DS; 
#=GF RL   J Mol Biol. 2003;330:225-234.
#=GF DR   INTERPRO; IPR014838;
#=GF DR   SCOP; 1ng7; sf;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in positive-strand RNA viruses.  The 3A
#=GF CC   protein is a critical component of the poliovirus replication
#=GF CC   complex, and is also an inhibitor of host cell ER to Golgi
#=GF CC   transport.
#=GF SQ   6
#=GS A0A0V0T2H0_9BILA/597-654    AC A0A0V0T2H0.1
#=GS A0A0B5GG60_9PICO/1584-1633  AC A0A0B5GG60.1
#=GS A0A0V0T4S7_9BILA/1405-1462  AC A0A0V0T4S7.1
#=GS A0A0V1KK42_9BILA/324-381    AC A0A0V1KK42.1
#=GS POLG_POL1M/1457-1515        AC P03300.3
#=GS POLG_HRV8A/1421-1472        AC P07210.3
A0A0V0T2H0_9BILA/597-654               gppkfrp-------IRISLEEKPAPDAISDLLASVDSEEVRQYCREQGWII-PETPTNVERHLNRA..............
A0A0B5GG60_9PICO/1584-1633             ..egmkn-------------RAPCPKEIQDLLRAVPDPKILSYCEQQGWIF---------------pedmkrlhvkrecn
A0A0V0T4S7_9BILA/1405-1462             gppkfrp-------IRISLEEKPAPDAISDLLASVDSEEVRQYCRDQGWIV-PDSPTNVERHLNRA..............
A0A0V1KK42_9BILA/324-381               gppkfrp-------IRISLEEKPAPDAISDLLASVDSEEVRQYCRDQGWIV-PDSPTNVERHLNRA..............
POLG_POL1M/1457-1515                   .......GPLQYKDLKIDIKTSPPPECINDLLQAVDSQEVRDYCEKKGWIVNITSQVQTERNINRA..............
POLG_HRV8A/1421-1472                   .......AIFQGIDLQ-----SPPPPAIADLLRSVKTPEIIKYCQDNNWIV--PAECSIERDLGIA..............
#=GC seq_cons                          ...th+s.......l+IslccpPsP-AIuDLLtSVDSpEVRpYCc-QGWIV..so.sslERcLNRA..............
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