GenomeNet

Database: Pfam
Entry: P53_TAD
LinkDB: P53_TAD
Original site: P53_TAD 
#=GF ID   P53_TAD
#=GF AC   PF08563.11
#=GF DE   P53 transactivation motif
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_3515 (release 19.0)
#=GF GA   20.00 20.00;
#=GF TC   21.00 24.20;
#=GF NC   19.60 19.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Motif
#=GF WK   P53
#=GF RN   [1]
#=GF RM   8875929
#=GF RT   Structure of the MDM2 oncoprotein bound to the p53 tumor
#=GF RT   suppressor transactivation domain. 
#=GF RA   Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine
#=GF RA   AJ, Pavletich NP; 
#=GF RL   Science. 1996;274:948-953.
#=GF RN   [2]
#=GF RM   16159876
#=GF RT   Structural details on mdm2-p53 interaction. 
#=GF RA   Chi SW, Lee SH, Kim DH, Ahn MJ, Kim JS, Woo JY, Torizawa T,
#=GF RA   Kainosho M, Han KH; 
#=GF RL   J Biol Chem. 2005;280:38795-38802.
#=GF DR   INTERPRO; IPR013872;
#=GF DR   SO; 0001067; polypeptide_motif;
#=GF CC   The binding of the p53 transactivation domain by regulatory
#=GF CC   proteins regulates p53 transcription activation.  This motif is
#=GF CC   comprised of a single amphipathic alpha helix and contains a
#=GF CC   highly conserved sequence [1-2].
#=GF SQ   124
#=GS G3R2U9_GORGO/6-30         AC G3R2U9.1
#=GS A0A2I3HEB4_NOMLE/6-30     AC A0A2I3HEB4.1
#=GS H0XGB0_OTOGA/6-30         AC H0XGB0.1
#=GS W4XZV6_STRPU/15-39        AC W4XZV6.1
#=GS Q80ZA1_MOUSE/9-33         AC Q80ZA1.1
#=GS P53_SHEEP/6-30            AC P51664.1
#=GS G3Q6V7_GASAC/10-32        AC G3Q6V7.1
#=GS Q549C9_MOUSE/9-33         AC Q549C9.1
#=GS A0A1U8BI05_MESAU/6-30     AC A0A1U8BI05.1
#=GS A0A2I3HA34_NOMLE/6-30     AC A0A2I3HA34.1
#=GS L5M0C7_MYODS/5-29         AC L5M0C7.1
#=GS H3B1Z4_LATCH/6-29         AC H3B1Z4.1
#=GS P53_CANLF/6-30            AC Q29537.2
#=GS F7GNX0_CALJA/6-30         AC F7GNX0.1
#=GS A0A2I2ZTB3_GORGO/6-30     AC A0A2I2ZTB3.1
#=GS A0A2I3SYN1_PANTR/6-30     AC A0A2I3SYN1.1
#=GS A0A2K5N3I9_CERAT/6-30     AC A0A2K5N3I9.1
#=GS A0A0F8AIC7_LARCR/4-28     AC A0A0F8AIC7.1
#=GS A0A2I3N9A3_PAPAN/6-30     AC A0A2I3N9A3.1
#=GS G1MEP6_AILME/6-30         AC G1MEP6.1
#=GS E7EQX7_HUMAN/6-30         AC E7EQX7.1
#=GS A0A1S3IK29_LINUN/32-56    AC A0A1S3IK29.1
#=GS C3VC56_SHEEP/6-30         AC C3VC56.1
#=GS P53_MOUSE/6-30            AC P02340.3
#=GS L7N1B2_MYOLU/7-31         AC L7N1B2.1
#=GS F1PI27_CANLF/8-32         AC F1PI27.1
#=GS P53_MACMU/6-30            AC P56424.1
#=GS M3YC88_MUSPF/6-30         AC M3YC88.1
#=GS G3ULT4_LOXAF/6-30         AC G3ULT4.1
#=GS G3UAZ0_LOXAF/6-30         AC G3UAZ0.1
#=GS A0A2K5JJA8_COLAP/6-30     AC A0A2K5JJA8.1
#=GS A0A2K5JJ89_COLAP/6-30     AC A0A2K5JJ89.1
#=GS L5JZ91_PTEAL/6-30         AC L5JZ91.1
#=GS V4A869_LOTGI/10-34        AC V4A869.1
#=GS A0A2I2ZK26_GORGO/6-30     AC A0A2I2ZK26.1
#=GS I3KRX9_ORENI/9-33         AC I3KRX9.1
#=GS A0A096MBY3_POEFO/4-28     AC A0A096MBY3.1
#=GS A0A2K5N3M9_CERAT/6-30     AC A0A2K5N3M9.1
#=GS A0A2K5N3J8_CERAT/6-30     AC A0A2K5N3J8.1
#=GS A0A0G2KBB2_RAT/6-30       AC A0A0G2KBB2.1
#=GS P53_XIPMA/2-26            AC Q92143.2
#=GS A0A2I3GF05_NOMLE/6-30     AC A0A2I3GF05.1
#=GS G3WS63_SARHA/4-31         AC G3WS63.1
#=GS S4R334_HUMAN/6-30         AC S4R334.1
#=GS A0A087XP53_POEFO/1-25     AC A0A087XP53.2
#=GS E9PCY9_HUMAN/6-30         AC E9PCY9.8
#=GS A0A2I3T645_PANTR/6-30     AC A0A2I3T645.1
#=GS A0A2K5N3F4_CERAT/6-30     AC A0A2K5N3F4.1
#=GS P53_RABIT/6-30            AC Q95330.1
#=GS H2U135_TAKRU/2-26         AC H2U135.1
#=GS A0A2K5JJ67_COLAP/6-30     AC A0A2K5JJ67.1
#=GS E7EMR6_HUMAN/6-30         AC E7EMR6.1
#=GS A0A0D9RG12_CHLSB/6-30     AC A0A0D9RG12.1
#=GS A0A1D5RL03_MACMU/6-30     AC A0A1D5RL03.1
#=GS C0H8X1_SALSA/4-26         AC C0H8X1.1
#=GS A0A091CJU7_FUKDA/6-30     AC A0A091CJU7.1
#=GS A0A1S3RGF1_SALSA/38-60    AC A0A1S3RGF1.1
#=GS F7A9U0_XENTR/5-29         AC F7A9U0.1
#=GS H2NSL2_PONAB/6-30         AC H2NSL2.1
#=GS P53_BOVIN/6-30            AC P67939.1
#=GS G3TS21_LOXAF/8-32         AC G3TS21.1
#=GS A0A2K5JJ46_COLAP/6-30     AC A0A2K5JJ46.1
#=GS M7CJF0_CHEMY/2-26         AC M7CJF0.1
#=GS H2QC53_PANTR/6-30         AC H2QC53.1
#=GS G3UK14_LOXAF/6-30         AC G3UK14.1
#=GS A0A2I3MD32_PAPAN/6-30     AC A0A2I3MD32.1
#=GS L9KM90_TUPCH/20-44        AC L9KM90.1
#=GS G3UJ00_LOXAF/6-30         AC G3UJ00.1
#=GS A0A2I2YTF6_GORGO/6-30     AC A0A2I2YTF6.1
#=GS A0A1U7Q2G4_MESAU/6-30     AC A0A1U7Q2G4.1
#=GS P53_MESAU/6-30            AC Q00366.1
#=GS G3UHE5_LOXAF/6-30         AC G3UHE5.1
#=GS G1SEU0_RABIT/6-30         AC G1SEU0.1
#=GS A0A1B8Y044_XENTR/5-29     AC A0A1B8Y044.1
#=GS F7F8L3_MACMU/6-30         AC F7F8L3.1
#=GS A0A0G2KB75_RAT/6-30       AC A0A0G2KB75.1
#=GS A0A1S3EYG2_DIPOR/29-53    AC A0A1S3EYG2.1
#=GS C3XPU2_BRAFL/1-25         AC C3XPU2.1
#=GS G3UI57_LOXAF/6-30         AC G3UI57.1
#=GS A0A286XW13_CAVPO/6-30     AC A0A286XW13.1
#=GS A0A096P2R8_PAPAN/6-30     AC A0A096P2R8.1
#=GS A0A2I3NCU7_PAPAN/6-30     AC A0A2I3NCU7.1
#=GS G7PTI9_MACFA/6-30         AC G7PTI9.1
#=GS G3T035_LOXAF/6-30         AC G3T035.1
#=GS P53_RAT/6-30              AC P10361.1
#=GS G1RF61_NOMLE/6-30         AC G1RF61.2
#=GS K1RC48_CRAGI/211-235      AC K1RC48.1
#=GS A0A2I3LC67_PAPAN/6-30     AC A0A2I3LC67.1
#=GS A0A1S2ZRH2_ERIEU/2-31     AC A0A1S2ZRH2.1
#=GS G1U940_RABIT/1-25         AC G1U940.1
#=GS P53_CAVPO/6-30            AC Q9WUR6.1
#=GS A0A1S3EYC1_DIPOR/29-53    AC A0A1S3EYC1.1
#=GS A0A1U7U5H4_TARSY/6-29     AC A0A1U7U5H4.1
#=GS A0A2I3T5N8_PANTR/6-30     AC A0A2I3T5N8.1
#=GS Q9EQL0_RAT/6-30           AC Q9EQL0.1
#=GS F7GP14_CALJA/6-30         AC F7GP14.1
#=GS I3N5N2_ICTTR/6-30         AC I3N5N2.1
#=GS I3LA53_PIG/6-30           AC I3LA53.2
#=GS W5N8V9_LEPOC/3-27         AC W5N8V9.1
#=GS A0A0P7YNA4_9TELE/112-136  AC A0A0P7YNA4.1
#=GS G3UDE4_LOXAF/6-30         AC G3UDE4.1
#=GS A0A1S3II34_LINUN/26-50    AC A0A1S3II34.1
#=GS A0A2I3T303_PANTR/6-30     AC A0A2I3T303.1
#=GS A0A087WZU8_HUMAN/6-30     AC A0A087WZU8.1
#=GS G5B5D6_HETGA/6-30         AC G5B5D6.1
#=GS I7HIK9_MOUSE/6-30         AC I7HIK9.1
#=GS P53_FELCA/6-30            AC P41685.1
#=GS A0A2I2ZNQ9_GORGO/6-30     AC A0A2I2ZNQ9.1
#=GS A0A2I3GX68_NOMLE/6-30     AC A0A2I3GX68.1
#=GS F7A9M9_XENTR/5-29         AC F7A9M9.1
#=GS H2U134_TAKRU/2-26         AC H2U134.1
#=GS P53_HUMAN/6-30            AC P04637.4
#=GS P53_HUMAN/6-30            DR PDB; 3DAC B; 17-29;
#=GS P53_HUMAN/6-30            DR PDB; 3DAB F; 16-27;
#=GS P53_HUMAN/6-30            DR PDB; 2K8F B; 6-30;
#=GS P53_HUMAN/6-30            DR PDB; 1YCQ B; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 2MWY B; 115-129;
#=GS P53_HUMAN/6-30            DR PDB; 5HOU A; 1006-1030;
#=GS P53_HUMAN/6-30            DR PDB; 3DAB D; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 2Z5T P; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 2Z5S P; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 2Z5T R; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 2L14 B; 13-30;
#=GS P53_HUMAN/6-30            DR PDB; 2Z5S Q; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 3DAC P; 17-28;
#=GS P53_HUMAN/6-30            DR PDB; 4HFZ D; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 2Z5S R; 18-27;
#=GS P53_HUMAN/6-30            DR PDB; 1YCR B; 17-29;
#=GS P53_HUMAN/6-30            DR PDB; 4HFZ B; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 3DAB B; 17-28;
#=GS P53_HUMAN/6-30            DR PDB; 2LY4 B; 14-30;
#=GS P53_HUMAN/6-30            DR PDB; 2Z5T Q; 17-27;
#=GS P53_HUMAN/6-30            DR PDB; 5HPD A; 3006-3030;
#=GS P53_HUMAN/6-30            DR PDB; 3DAB H; 18-28;
#=GS W5N8V4_LEPOC/3-27         AC W5N8V4.1
#=GS A0A2K5JJ56_COLAP/6-30     AC A0A2K5JJ56.1
#=GS P53_PIG/6-30              AC Q9TUB2.1
#=GS A0A2K5TIV2_FELCA/109-133  AC A0A2K5TIV2.1
#=GS G3U6U6_LOXAF/6-30         AC G3U6U6.1
#=GS E9PFT5_HUMAN/6-30         AC E9PFT5.1
#=GS T0MFN1_CAMFR/6-30         AC T0MFN1.1
#=GS G3Q6V4_GASAC/10-34        AC G3Q6V4.1
#=GS J3KP33_HUMAN/6-30         AC J3KP33.1
#=GS G3U6D1_LOXAF/6-30         AC G3U6D1.1
#=GS H3CXQ0_TETNG/2-26         AC H3CXQ0.1
#=GS K7G3P4_PELSI/5-29         AC K7G3P4.1
G3R2U9_GORGO/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A2I3HEB4_NOMLE/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
H0XGB0_OTOGA/6-30                    ......SDLTIEPPLSQETFSDLWKLLPENN....
W4XZV6_STRPU/15-39                   ......SQEMADLPLSQETFHALWATLQND-v...
Q80ZA1_MOUSE/9-33                    ......SDISLELPLSQETFSGLWKLLPP--ed..
P53_SHEEP/6-30                       .....a-ELGVEPPLSQETFSDLWNLLPENN....
G3Q6V7_GASAC/10-32                   .....l-ALGQDLPDSQDSFAELWGNV----lt..
Q549C9_MOUSE/9-33                    ......SDISLELPLSQETFSGLWKLLPP--ed..
A0A1U8BI05_MESAU/6-30                ......SDLSIELPLSQETFSDLWKLLPPNN....
A0A2I3HA34_NOMLE/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
L5M0C7_MYODS/5-29                    .....q-LEVVDPPLSQETFSDLWNSATAW-g...
H3B1Z4_LATCH/6-29                    ......SESGLE-PLSQESFADLWNLLPTS-m...
P53_CANLF/6-30                       ......SELNIDPPLSQETFSELWNLLPENN....
F7GNX0_CALJA/6-30                    ......SDLSIEPPLSQETFSDLWKLLPENN....
A0A2I2ZTB3_GORGO/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A2I3SYN1_PANTR/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A2K5N3I9_CERAT/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A0F8AIC7_LARCR/4-28                ......EQDFGSLPLSQDSFKALWESVMPP-s...
A0A2I3N9A3_PAPAN/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
G1MEP6_AILME/6-30                    ......SELTIDPPLSQETFSELWNLLPENN....
E7EQX7_HUMAN/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A1S3IK29_LINUN/32-56               .....g-NEGVNPPLSQETFDGLWDQLM---iqt.
C3VC56_SHEEP/6-30                    .....a-ELGVEPPLSQETFSDLWNLLPENN....
P53_MOUSE/6-30                       ......SDISLELPLSQETFSGLWKLLPP--ed..
L7N1B2_MYOLU/7-31                    .....q-PEVMDPPLSQETFSDLWNLLHDN-d...
F1PI27_CANLF/8-32                    ......SELNIDPPLSQETFSELWNLLPENN....
P53_MACMU/6-30                       ......SDPSIEPPLSQETFSDLWKLLPENN....
M3YC88_MUSPF/6-30                    ......SELTIDPPLSQETFSELWNLLPENN....
G3ULT4_LOXAF/6-30                    ......SDLSIELPLSQETFSYLGKLLSEK-l...
G3UAZ0_LOXAF/6-30                    ......SDLSTELPLSQETFSYLGKLLPEK-l...
A0A2K5JJA8_COLAP/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A2K5JJ89_COLAP/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
L5JZ91_PTEAL/6-30                    ......SELNMEPPLSQETFSDLWKLLPQNN....
V4A869_LOTGI/10-34                   .....g-NTNSQPPMSQDTFDFLWKTLGDAT....
A0A2I2ZK26_GORGO/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
I3KRX9_ORENI/9-33                    ......LQLSQNLPLSQDSFKELWDKIIPST....
A0A096MBY3_POEFO/4-28                ......METNFPLPLSQDTFHELWNTVVLST....
A0A2K5N3M9_CERAT/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A2K5N3J8_CERAT/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A0G2KBB2_RAT/6-30                  ......SDMSIELPLSQETFSCLWKLLPPD-d...
P53_XIPMA/2-26                       .....e-EADLTLPLSQDTFHDLWNNVFLST....
A0A2I3GF05_NOMLE/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
G3WS63_SARHA/4-31                    ......SLSDLEPPLSQETFSDLWKLQWNN-lpdd
S4R334_HUMAN/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A087XP53_POEFO/1-25                ......METNFPLPLSQDTFHELWNTVVLST....
E9PCY9_HUMAN/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A2I3T645_PANTR/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A2K5N3F4_CERAT/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
P53_RABIT/6-30                       ......SDLSLEPPLSQETFSDLWKLLPENN....
H2U135_TAKRU/2-26                    ......EDEGFSLPLSQDTFQDLWENVMLT-h...
A0A2K5JJ67_COLAP/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
E7EMR6_HUMAN/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A0D9RG12_CHLSB/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A1D5RL03_MACMU/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
C0H8X1_SALSA/4-26                    .....l-VENVSLPLSQESFEDLWKM-----nln.
A0A091CJU7_FUKDA/6-30                ......SDLSIEPPLSQETFSDLWKLLPENN....
A0A1S3RGF1_SALSA/38-60               .....l-VENVSLPLSQESFEDLWKM-----nln.
F7A9U0_XENTR/5-29                    ......SETGMEPPLSQETFEDLWSLLPDP-l...
H2NSL2_PONAB/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
P53_BOVIN/6-30                       .....a-ELNVEPPLSQETFSDLWNLLPENN....
G3TS21_LOXAF/8-32                    ......SDLSTELLLSQETFSYLGKLLPEK-l...
A0A2K5JJ46_COLAP/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
M7CJF0_CHEMY/2-26                    ......LDPGLEPPLSQESFSDWWSMMLQPT....
H2QC53_PANTR/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
G3UK14_LOXAF/6-30                    ......SDLSTELPLSQETFSYLGKLLPEK-l...
A0A2I3MD32_PAPAN/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
L9KM90_TUPCH/20-44                   ......SDLSVELPLSQETFSDLWSLLPG--qd..
G3UJ00_LOXAF/6-30                    ......SDLSTELPLSQETFSYLGKLLPEK-l...
A0A2I2YTF6_GORGO/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A1U7Q2G4_MESAU/6-30                ......SDLSIELPLSQETFSDLWKLLPPNN....
P53_MESAU/6-30                       ......SDLSIELPLSQETFSDLWKLLPPNN....
G3UHE5_LOXAF/6-30                    ......SDLSTELPLSQGTFSYLGKLLPEK-l...
G1SEU0_RABIT/6-30                    ......SDLSLEPPLSQETFSDLWKLLPENN....
A0A1B8Y044_XENTR/5-29                ......SETGMEPPLSQETFEDLWSLLPDP-l...
F7F8L3_MACMU/6-30                    ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A0G2KB75_RAT/6-30                  ......SDMSIELPLSQETFSCLWKLLPPD-d...
A0A1S3EYG2_DIPOR/29-53               ......SDLNIDLPLSHESFSDFWKLLPDD-s...
C3XPU2_BRAFL/1-25                    ......MSQGSNPPLSQETFNQLWNQINSVT....
G3UI57_LOXAF/6-30                    ......SDLSTELPLSQETFSCLGKLLPEK-v...
A0A286XW13_CAVPO/6-30                ......SDLSIEPPLSQETFSDLWKLLPENN....
A0A096P2R8_PAPAN/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A2I3NCU7_PAPAN/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
G7PTI9_MACFA/6-30                    ......SDPSIEPPLSQETFSDLWKLLPENN....
G3T035_LOXAF/6-30                    ......SDLSTELPLSQETFSYLWELLPENP....
P53_RAT/6-30                         ......SDMSIELPLSQETFSCLWKLLPPD-d...
G1RF61_NOMLE/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
K1RC48_CRAGI/211-235                 ......SSSVTGPPLSQEAFDYLWHSLDACT....
A0A2I3LC67_PAPAN/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
A0A1S2ZRH2_ERIEU/2-31                medlpl-ELDVDTPLSQTTFSELWNLLPDK-d...
G1U940_RABIT/1-25                    ......SVLSLEPPLSQETLSDLWKLLSEY-n...
P53_CAVPO/6-30                       ......SDLSIEPPLSQETFSDLWKLLPENN....
A0A1S3EYC1_DIPOR/29-53               ......SDLNIDLPLSHESFSDFWKLLPDD-s...
A0A1U7U5H4_TARSY/6-29                ......SDLSIE-PLSQETFSDLWKLLPENN....
A0A2I3T5N8_PANTR/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
Q9EQL0_RAT/6-30                      ......SDMSIELPLSQETFSCLWKLLPPD-d...
F7GP14_CALJA/6-30                    ......SDLSIEPPLSQETFSDLWKLLPENN....
I3N5N2_ICTTR/6-30                    ......SDLSIEPPLSQETFSDLWNLLPENN....
I3LA53_PIG/6-30                      ......SELGVEPPLSQETFSDLWKLV----esqp
W5N8V9_LEPOC/3-27                    .....d-PEPEGLPLSQESFQELWNMVA---vpp.
A0A0P7YNA4_9TELE/112-136             ......EEDMPSLPFSQESFQELWKDLMPA-p...
G3UDE4_LOXAF/6-30                    ......SDLSTELPLSQETFSYLGKLLPEK-l...
A0A1S3II34_LINUN/26-50               .....g-NEGVNPPLSQETFDGLWDQLM---iqt.
A0A2I3T303_PANTR/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A087WZU8_HUMAN/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
G5B5D6_HETGA/6-30                    ......SDLSIEPPLSQETFSDLWKLLPENN....
I7HIK9_MOUSE/6-30                    ......SDISLELPLSQETFSGLWKLLPP--ed..
P53_FELCA/6-30                       .....l-ELTIEPPLSQETFSELWNLLPENN....
A0A2I2ZNQ9_GORGO/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
A0A2I3GX68_NOMLE/6-30                ......SDPSVEPPLSQETFSDLWKLLPENN....
F7A9M9_XENTR/5-29                    ......SETGMEPPLSQETFEDLWSLLPDP-l...
H2U134_TAKRU/2-26                    ......EDEGFSLPLSQDTFQDLWENVDVC-m...
P53_HUMAN/6-30                       ......SDPSVEPPLSQETFSDLWKLLPENN....
#=GR P53_HUMAN/6-30            SS    ......CXSTTSXSSSTCHHHHHHHTSSTSC....
W5N8V4_LEPOC/3-27                    .....d-PEPEGLPLSQESFQELWNMVIV--lh..
A0A2K5JJ56_COLAP/6-30                ......SDPSIEPPLSQETFSDLWKLLPENN....
P53_PIG/6-30                         ......SELGVEPPLSQETFSDLWKLLPENN....
A0A2K5TIV2_FELCA/109-133             .....l-ELTIEPPLSQETFSELWNLLPENN....
G3U6U6_LOXAF/6-30                    ......SDLSTELPLSQGTFSYLGKLLPEK-l...
E9PFT5_HUMAN/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
T0MFN1_CAMFR/6-30                    ......SELGVEPPLSQETFSDLWKLLPENN....
G3Q6V4_GASAC/10-34                   .....l-ALGQDLPDSQDSFAELWGNVVSPP....
J3KP33_HUMAN/6-30                    ......SDPSVEPPLSQETFSDLWKLLPENN....
G3U6D1_LOXAF/6-30                    ......SDLSTELPLSQGTFSYLGKLLPEK-l...
H3CXQ0_TETNG/2-26                    ......EEETFSLPLSQDTFQDLWENVAA--ps..
K7G3P4_PELSI/5-29                    ......LDTGLDLPLSQESFSDLWKTLSP--la..
#=GC SS_cons                         ......CXSTTSXSSSTCHHHHHHHTSSTSC....
#=GC seq_cons                        ......SD.SlEPPLSQETFSDLWKLLPEss....
//
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