GenomeNet

Database: Pfam
Entry: PDZ_4
LinkDB: PDZ_4
Original site: PDZ_4 
#=GF ID   PDZ_4
#=GF AC   PF17816.3
#=GF DE   PDZ domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD:EUF02267
#=GF GA   23.10 23.10;
#=GF TC   23.10 23.10;
#=GF NC   23.00 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   PDZ_domain
#=GF CL   CL0466
#=GF RN   [1]
#=GF RM   19064254
#=GF RT   Structural basis for activation and inhibition of the secreted
#=GF RT   chlamydia protease CPAF.
#=GF RA   Huang Z, Feng Y, Chen D, Wu X, Huang S, Wang X, Xiao X, Li W,
#=GF RA   Huang N, Gu L, Zhong G, Chai J;
#=GF RL   Cell Host Microbe. 2008;4:529-542.
#=GF DR   INTERPRO; IPR041126;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents a PDZ domain that is found in the CPAF
#=GF CC   protein from chlamydia trachomatis [1].
#=GF SQ   28
#=GS G8QZG9_OWEHD/24-106       AC G8QZG9.1
#=GS A0A1Y6CCA3_9PROT/130-237  AC A0A1Y6CCA3.1
#=GS A0A265QB29_9FIRM/271-374  AC A0A265QB29.1
#=GS A0A0P7BQ72_9BACT/102-209  AC A0A0P7BQ72.1
#=GS A0A0E4A048_9BACT/107-187  AC A0A0E4A048.1
#=GS F2IG98_FLUTR/115-217      AC F2IG98.1
#=GS A0A0H5DR29_9BACT/104-220  AC A0A0H5DR29.1
#=GS S7IJH0_CHLPS/106-213      AC S7IJH0.1
#=GS Q023W5_SOLUE/100-213      AC Q023W5.1
#=GS F8KXV5_PARAV/107-223      AC F8KXV5.1
#=GS A0A327NP39_9BACT/124-176  AC A0A327NP39.1
#=GS A0A090D0X2_9BACT/107-220  AC A0A090D0X2.1
#=GS A0A4Q8UEC9_9ALTE/118-232  AC A0A4Q8UEC9.1
#=GS Y858_CHLTR/106-215        AC O84866.2
#=GS Y858_CHLTR/106-215        DR PDB; 3DPM B; 114-223;
#=GS Y858_CHLTR/106-215        DR PDB; 3DPM A; 114-223;
#=GS Y858_CHLTR/106-215        DR PDB; 3DJA A; 114-223;
#=GS Y858_CHLTR/106-215        DR PDB; 3DOR B; 114-223;
#=GS Y858_CHLTR/106-215        DR PDB; 3DPN A; 114-222;
#=GS Y858_CHLTR/106-215        DR PDB; 3DPN B; 114-222;
#=GS Y858_CHLTR/106-215        DR PDB; 3DJA B; 114-223;
#=GS Y858_CHLTR/106-215        DR PDB; 3DOR A; 114-223;
#=GS A0A1C2GS27_9SPHI/242-322  AC A0A1C2GS27.1
#=GS A0A515A950_9BACT/106-179  AC A0A515A950.1
#=GS A0A0C1HIX5_9BACT/105-221  AC A0A0C1HIX5.1
#=GS A0A0U5ERK9_9BACT/111-227  AC A0A0U5ERK9.1
#=GS A0A1M5C9U6_9FLAO/102-177  AC A0A1M5C9U6.1
#=GS A0A212KVR8_9CHLA/113-228  AC A0A212KVR8.1
#=GS A0A176U208_9FIRM/261-366  AC A0A176U208.1
#=GS Q6MCQ9_PARUW/110-226      AC Q6MCQ9.1
#=GS A0A0C1K2I2_9BACT/107-232  AC A0A0C1K2I2.1
#=GS A0A212KTS0_9CHLA/115-230  AC A0A212KTS0.1
#=GS A0A212KTN4_9CHLA/115-243  AC A0A212KTN4.1
#=GS A0A640Q9N8_9FLAO/102-175  AC A0A640Q9N8.1
#=GS D6YW40_WADCW/105-238      AC D6YW40.1
#=GS U5Q8A5_9BACT/245-357      AC U5Q8A5.1
G8QZG9_OWEHD/24-106                  ....nyr---YFPFSIKMV-DGRVFI-W-D...NY.S...ND.....................SSLKRGDEIISINGNSIQSIIGRMYKC.IS.......SDGNI-------------.---...--...--------..----.--.---.......-----------------ennlrvrlqsgfawmyylfeaqpe......
A0A1Y6CCA3_9PROT/130-237             ....ptv---HLGFQIHHV-DQKYIITGMD...SD.L...E-.....................EVLEIGDQIFALDGEPIDLITRDLQQY.IS.......SSS-PSYREQLAVQALTK.RSF...RY...PKS-P--R..TRLT.IR.SRN.......GEIKDLTLAWHYDYEVI..............................
A0A265QB29_9FIRM/271-374             ..yiapv-------YLTK-AEGKYVVERIE...NEyK...DT.....................CPLLVGDIPIEINGKKIEDVIEYLKKY.IS.......IPNNEKTLNPMGSMILIS.HEK...IM...NITVLRDN..DKI-.--.---.......-----------------eyelkgmpfnlynyn...............
A0A0P7BQ72_9BACT/102-209             ....hqq---VLPFVLQEV-EGRFLI--QY...NG.S...SD.....................STLQRGLTLKEINGKPVEEVIDEVKGYlGT.......DNNNDLAKGLYASRSLYA.YYG...KL...HPL--KDS..VTVV.VK.---.......-----------------ndtlnelethklatltrk............
A0A0E4A048_9BACT/107-187             .....tr---FLPFYIRLV-ESQYFI--SH...NV.S...SD.....................TTLQRGTELLTINGRPVADVHRELMNA.DH.......SGSD--------------.---...--...--------..----.--.---.......-----------------gdnltgrrqwsmvqfadyyaawfg......
F2IG98_FLUTR/115-217                 .....nn---QIPFEIKHI-EGRIYI--SN...TV.D...DS.....................LDFQMNDELIRINNRPVKDIIDQLLEM.ET......gDGFTPIFRNALIERRFGI.Y--...--...--------..----.--.---.......-----------------mlflsgipqeyviefknskgevkqtavqpt
A0A0H5DR29_9BACT/104-220             .......EVSYLPFRIKGA-GRRYFISHID...WE.KfptQT.....................DPVEVGDEVLTFDGQPTRDEVLKIKER.EV.......GAGDTETDWSLAETFLTK.RSG...AL...GHLVPKGA..VELK.VRsRKS.......GSIYTVNLIWRYYPEKI..............................
S7IJH0_CHLPS/106-213                 .......ESSYLPYTLKLSSNNRCFV--VD...VH.T...YH.....................SDISVGDEILEMDGIPILEAIESIRTG.RG.......VPS----DYAAATRMLFS.RSA...SL...GHQVPVGI..ATLK.IR.RPS.......GLTRTLKVKWRHTPEHI..............................
Q023W5_SOLUE/100-213                 ......f--ASLGFSVDI-YDGVLLVDSIN...RT.TlpsKD.....................YPFTTGDRLISVDGRDMTMMLQDFANY.AA.......WGN-PIASKRLAAARITS.RSQ...SImphATDVIGKS..ATVV.IQ.RQG.......GATETYTIPW-------vvsg..........................
F8KXV5_PARAV/107-223                 .......EMASLPFHLQG-AEGRYFITWIN...EE.KlpeEC.....................LDWSIGDEVIAFDGQDIHEFVQNLRRS.EH.......DRHNEKTDQRFAERSLTL.RAG...MF...AEDVPQGN..VEVDlIH.KKT.......GEQKSYVLTWTYHPEQV..............................
A0A327NP39_9BACT/124-176             ....kik---IFPFTFKII-NRRFYI--VK...SA.S...RP.....................SPIKVGSELISINGRPMEEILNRL---.--.......------------------.---...--...--------..----.--.---.......-----------------lpai..........................
A0A090D0X2_9BACT/107-220             .......EMACLPFKVKG-AEGRYFITWVD...KDrI...ND.....................HSLAIGDELLEFNGKPVHEVVTKLKNE.EM.......LSSNEETDYGLAEVNLTS.RIG...AL...GFSVPKGP..VKLK.IK.HKN.......KKASVLNLEWDYFDEKI..............................
A0A4Q8UEC9_9ALTE/118-232             .....gv---FLPFRWHWV-EQRGFITQVS...AS.-...AT.....................EQLNIGDEILTIDGRPLTDLVEEVIQY.IP......yDGNTEWTRNAGVAQSLEF.NGGavdHF...GSMLWQNKpeVTLR.VR.DKD.......ANVRSL-----------tvarinyde.....................
Y858_CHLTR/106-215                   .......ESAYLPYTVQKSSDGRFYF--VD...IM.T...FS.....................SEIRVGDELLEVDGAPVQDVLATLYGS.NH.......KGT--AAEESAALRTLFS.RMA...SL...GHKVPSGR..TTLK.IR.RPF.......GTTREVRVKWRYVPEGV..............................
#=GR Y858_CHLTR/106-215        SS    .......-EEE-SEEEEE-TTS-EEE--EE...E-.S...SS.....................SSS-TT-EEEEETTEEHHHHHHTTS-T.T-.......-----HHHHHHHHHHHTE.EEG...GG...T-----SE..EEEE.EE.ETT.......SEEEEEEEE-EEE---S..............................
A0A1C2GS27_9SPHI/242-322             ....rln----MPFDLSF-INGRFYIIKSR...YD.Sl.mNA.....................LNFKIGDEIVGINGKPVADRINDLKPL.T-.......------------------.---...--...--------..----.--.---.......-----------------tgtnelsvyrnigamlfkidtvasi.....
A0A515A950_9BACT/106-179             ....qtr---FLPFYIRPV-DTRYFI--SH...NV.S...AD.....................TSLQRGTELLTINGRTIGDLHTELMNS.DH.......SGSD--------------.---...--...--------..----.--.---.......-----------------gdnltgrrqwslvqfa..............
A0A0C1HIX5_9BACT/105-221             .......EYAFLPFCVQGVQE-HYFVVWVDnlwAK.E...AK.....................VSLQVGDEILSFGGSPVREVVEEIRLS.AF.......GANYNETYQHLSEWQLTL.REA...FR...LQDVPQGP..IEIV.FR.KPN......sQQAHSFVVNWEYAPEEI..............................
A0A0U5ERK9_9BACT/111-227             .......ETASLPFGVK-SAEGRYFIDWID...PQ.QmpfYF.....................YEIQVGDELIAFDERPIGDVINELKEI.GN.......KNSNPFTDQALAEMKLTS.REG...QL...GDLVPRGA..VSIT.VQ.PAA......kEGSVTYQLIWNYTPEKI..............................
A0A1M5C9U6_9FLAO/102-177             ....awv---------K-IKDGKYYIADIRs.gFE.I...EE.....................TGLKVGDELLRINNRKIEDLVEEVLPK.SF.......KNPKGDVKEFFA------.---...--...--------..----.--.---.......-----------------nlwfagkhneer..................
A0A212KVR8_9CHLA/113-228             .......EEAHLPFDVM-SAEGRYFISHID...HS.AvssSE.....................FPFQIGDEIFYFDRLPIKKLVDELNMA.EE.......RGATTETDQRLAEMTLTH.RFG...TK...GHIVPSGR..IIVT.GR.DSY.......GKMHAAKLEWSYSPERV..............................
A0A176U208_9FIRM/261-366             ysapvrl---------IQ-AEGKYVVNL--...-V.Y...KD.....................CDLQVGDVIVAFNGRPIEDIIEEQKQY.IS.......ITEDDKILNQMEGFLLRA.KES...DM...DITVRRGD..DEIS.VK.I--.......-----------------qglsleedqavkvkeke.............
Q6MCQ9_PARUW/110-226                 .......ETATLPFDVKGVNN-RYFITWIDelkLP.P...ST.....................YTIKVGDEIIEFDGRPLGDVIEELKQH.GS.......KNSNPLTDQALAEIKLTN.RLG...WL...GDIIPQGP..VTIK.VHsRSK.......EVPLSYQLIWDYRPELI..............................
A0A0C1K2I2_9BACT/107-232             .......EMSFLPFRLEG-AEGRYFVAWLP...KN.S...QSyakidp.........sladmlANMQIGDEVLAFGNMPIDEYLKKFSLK.SF.......GKALNATDQRLAEQYLTL.RLA...SM...GYEVEQGG..VPIT.VRhHRS.......GRIDTYTPEWLYVPERI..............................
A0A212KTS0_9CHLA/115-230             .......ESAHLPFDVM-SAEGRYFISYID...HS.KvssSQ.....................FPFQVGDEILYFNHTPIGQVVDELIVT.EE.......RGATQETDQRKAENILTH.RLG...FM...GHMVPSGR..IKVT.GR.DSD.......GRMHAAKLQWSYTPERI..............................
A0A212KTN4_9CHLA/115-243             .......EKATLPFMIKGV-KGRYFFVYLD...RD.KlpkEI.....................FPFEIGDELLEFDGRPVHDVIQEIKHA.ELgndgtkiGDANDFTDQALAEIYLTS.RRD...N-...TNKIPKGP..ITLL.CR.AQKddegkpnSKAKEAQLVWDYFPEWV..............................
A0A640Q9N8_9FLAO/102-175             ....awv---------K-IKDGKYYIADIRs.gFE.I...EE.....................TGLKVGDELLRINNRKIEDLVEEVLPK.SF.......KNPKDNVKEFFAN-----.---...--...--------..----.--.---.......-----------------lwfagkhne.....................
D6YW40_WADCW/105-238                 .....ew--SAFPIVVKSVN-NRYFITKFD...FQ.L...SLsysdlafdfdeidierleaelQKCNLGDEVIAVNGVPVATLIEELIDS.EL.......NGDRTPTGYALAEKMLFT.RYG...RR...GHQVPKGD..FTLT.VK.PIF.......GKQHTVNLAWIHVAEW-v.............................
U5Q8A5_9BACT/245-357                 .vntipl-------IIS-VIENKYLVTGYY...KK.Eq.yDN.....................CQIKIGDEILEFDERPISDIISELLPY.CS.......-GVNKPTKLRIACDKLVLtNKG...EI...SLTIS---..----.--.---.......-----------------nsqgriarriktipsseinskarfqeek..
#=GC SS_cons                         .......-EEE-SEEEEE-TTS-EEE--EE...E-.S...SS.....................SSS-TT-EEEEETTEEHHHHHHTTS-T.T-.......-----HHHHHHHHHHHTE.EEG...GG...T-----SE..EEEE.EE.ETT.......SEEEEEEEE-EEE---S..............................
#=GC seq_cons                        ..........hLPFplchs.-GRYaIshlc...tp.p...ps.....................pslplGDEllphsG+Plp-llp-lhpt.pt.......tsss..scpthAp..Lh..+.s....h...s..l.ts...hpl..hp..........................................................
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