GenomeNet

Database: Pfam
Entry: PF00869
LinkDB: PF00869
Original site: PF00869 
#=GF ID   Flavi_glycoprot
#=GF AC   PF00869.20
#=GF DE   Flavivirus glycoprotein, central and dimerisation domains
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE   Pfam-B_146 (release 3.0)
#=GF GA   20.00 20.00;
#=GF TC   20.20 28.90;
#=GF NC   17.60 17.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   7753193
#=GF RT   The envelope glycoprotein from tick-borne encephalitis virus at
#=GF RT   2 A resolution. 
#=GF RA   Rey FA, Heinz FX, Mandl C, Kunz C, Harrison SC; 
#=GF RL   Nature 1995;375:291-298.
#=GF DR   INTERPRO; IPR011998;
#=GF DR   SCOP; 1svb; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF SQ   4
#=GS POLG_YEFV1/287-579   AC P03314.1
#=GS POLG_DEN1W/282-576   AC P17763.2
#=GS POLG_DEN1W/282-576   DR PDB; 4GSX B; 2-296;
#=GS POLG_DEN1W/282-576   DR PDB; 4GSX A; 2-296;
#=GS POLG_DEN1W/282-576   DR PDB; 4GT0 A; 2-296;
#=GS POLG_DEN1W/282-576   DR PDB; 4GT0 B; 2-296;
#=GS POLG_ZIKV/292-588    AC Q32ZE1.1
#=GS G7YB21_CLOSI/46-154  AC G7YB21.1
POLG_YEFV1/287-579              ......HCIGITDRDFIEGVHGGTWVSATLEQDKCVTVMAPDKPSLDISLETVAIDRPAEVRKVCYNAVLTHVKINDKCPSTGEAHLAEENEGDNACKRTYSDRGWGNGCGLFGKGSIVA.CAKFTCAKSMSLFEVDQTKIQYVIRAQLHVGAKQE.NWNTDIK---TLKFDALSGSQEVEFIGYGKATLECQVQTAVDFGNSYIAEMETESWIVDRQWAQDLTLPWQSG---SGGVWREMHHLVEFEPPHAATIRVLALGNQEGSLKTALTGAMRV-TKDTNdnnlyKLHGGHVSCRVKLSALTLKG.........
POLG_DEN1W/282-576              ......RCVGIGNRDFVEGLSGATWVDVVLEHGSCVTTMAKDKPTLDIELLKTEVTNPAVLRKLCIEAKISNTTTDSRCPTQGEATLVEEQDTNFVCRRTFVDRGWGNGCGLFGKGSLIT.CAKFKCVTKLEGKIVQYENLKYSVIVTVHTGDQHQ.VGNETTEHGTTATITPQAPTSEIQLTDYGALTLDCSPRTGLDFNEMVLLTMEKKSWLVHKQWFLDLPLPWTSGASTSQETWNRQDLLVTFKTAHAKKQEVVVLGSQEGAMHTALTGATEIQTSGTT.....TIFAGHLKCRLKMDKLTLKG.........
#=GR POLG_DEN1W/282-576   SS    ......-EEE--GGGEEE-SSSEEEEEEEEETT-EEEEEBTTS-EEEEEEEEEEEES-EEEEEEEEEEEEEEEEEEE--TTS-----GGGCSTTEEEEEEEEEESGGCT-SS-CEEEEEE.EEEEEEEEEEEEEE--GGGEEEEEEEEE-------.---------EEEEE-SSS-EEEEEETTTEEEEEEEEE-S-S-TTTEEEEEETTEEEEEEHHHHHT-SS-EEESS--SS---B-GGGTEEEEEEETTEEEEEE----HHHHHHHTTTSEEEEEETTE.....EEE--EEEEEEEEES--B--.........
POLG_ZIKV/292-588               ......RCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIELVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWGNGCGLFGKGSLVT.CAKFTCSKKMTGKSIQPENLEYRIMLSVHGSQHSGmIGYETDEDRAKVEVTPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWFHDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAEMDGAK....gRLFSGHLKCRLKMDKLRLKG.........
G7YB21_CLOSI/46-154             acdhtk-----------------------------------------------------------------------------------REDTVFSQHRRNGDTAWGVQCGFVTKGSRITtTVELICFKGLRGLEVAFRSIGYPVAVDEHRITYQE.LQDNFT-----PTRKATSKAQSISTITFGLKK----------------------------------------------------------------------------------------------.....--------------------vknavrcsr
#=GC SS_cons                    ......-EEE--GGGEEE-SSSEEEEEEEEETT-EEEEEBTTS-EEEEEEEEEEEES-EEEEEEEEEEEEEEEEEEE--TTS-----GGGCSTTEEEEEEEEEESGGCT-SS-CEEEEEE.EEEEEEEEEEEEEE--GGGEEEEEEEEE-------.---------EEEEE-SSS-EEEEEETTTEEEEEEEEE-S-S-TTTEEEEEETTEEEEEEHHHHHT-SS-EEESS--SS---B-GGGTEEEEEEETTEEEEEE----HHHHHHHTTTSEEEEEETTE.....EEE--EEEEEEEEES--B--.........
#=GC seq_cons                   ......+ClGlssRDFlEGhpGuTWVsssLEpstCVTsMA.DKPolDIpL.pstlsp.A.lRphChpA.lopht.ss+CPopGEAhLsccpDTsasC+RThsDRGWGNGCGLFGKGSllT.CAKFpCsKphpGhpVp.cslpYslhlslHsusppp.ltspssc...psphsspSsspElphhsaGthsL-CpspTulDFsp.hhhpMppcpWlVc+pWh.DlsLPWpuG...ut.hWpp.chLVpFcssHAtp.pVlsLGsQEGuh+TALsGAhch.hpssp.....plauGHlpCRlKhstLpLKG.........
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