GenomeNet

Database: Pfam
Entry: PF02249
LinkDB: PF02249
Original site: PF02249 
#=GF ID   MCR_alpha
#=GF AC   PF02249.17
#=GF DE   Methyl-coenzyme M reductase alpha subunit, C-terminal domain
#=GF AU   Mian N;0000-0003-4284-4749
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE   Pfam-B_2706 (release 5.2)
#=GF GA   25.00 25.00;
#=GF TC   36.50 35.00;
#=GF NC   24.80 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9367957
#=GF RT   Crystal structure of methyl-coenzyme M reductase: the key enzyme
#=GF RT   of biological methane formation 
#=GF RA   Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK; 
#=GF RL   Science 1997;278:1457-1462.
#=GF DR   INTERPRO; IPR009047;
#=GF DR   SCOP; 1mro; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Methyl-coenzyme M reductase (MCR) is the enzyme responsible for 
#=GF CC   microbial formation of methane. It is a hexamer composed of 2
#=GF CC   alpha (this family), 2 beta (Pfam:PF02241), and 2 gamma
#=GF CC   (Pfam:PF02240) subunits with two identical nickel porphinoid
#=GF CC   active sites [1]. The C-terminal domain is comprised of an
#=GF CC   all-alpha multi-helical bundle.
#=GF SQ   115
#=GS A0A1D2X2N6_9EURY/318-443  AC A0A1D2X2N6.1
#=GS A0A0P9E1V1_9ARCH/368-495  AC A0A0P9E1V1.1
#=GS E1RJD5_METP4/326-459      AC E1RJD5.1
#=GS F0TCV5_METLA/317-441      AC F0TCV5.1
#=GS A0A0P6VHH7_9EURY/330-462  AC A0A0P6VHH7.1
#=GS A0A1D2WLQ3_9EURY/318-442  AC A0A1D2WLQ3.1
#=GS A7I5T9_METB6/326-452      AC A7I5T9.1
#=GS A0A062V7W6_9EURY/331-457  AC A0A062V7W6.1
#=GS A0A0W7TIP2_9EURY/319-446  AC A0A0W7TIP2.1
#=GS Q0W339_METAR/322-447      AC Q0W339.1
#=GS F4BXY1_METSG/324-450      AC F4BXY1.1
#=GS A2SSD1_METLZ/326-459      AC A2SSD1.1
#=GS L0L0H0_METHD/330-462      AC L0L0H0.1
#=GS A0A1F2PDF7_9EURY/495-624  AC A0A1F2PDF7.1
#=GS A5ULM9_METS3/318-442      AC A5ULM9.1
#=GS A0A1F2P3I8_9EURY/318-445  AC A0A1F2P3I8.1
#=GS A0A1Y3GED3_9EURY/319-445  AC A0A1Y3GED3.1
#=GS A0A0U3E6Z6_9EURY/316-442  AC A0A0U3E6Z6.1
#=GS U6EF81_9EURY/317-441      AC U6EF81.1
#=GS A0A124G584_9EURY/326-459  AC A0A124G584.1
#=GS A6UWH2_META3/318-443      AC A6UWH2.1
#=GS J0RY59_9EURY/326-459      AC J0RY59.1
#=GS D5EAD6_METMS/332-464      AC D5EAD6.1
#=GS A0A0F8E165_9EURY/330-462  AC A0A0F8E165.1
#=GS A0A1Y3GE24_9EURY/318-444  AC A0A1Y3GE24.1
#=GS A0A1F2P3F1_9EURY/327-453  AC A0A1F2P3F1.1
#=GS D3E050_METRM/315-441      AC D3E050.1
#=GS MCRA_METKA/319-444        AC Q49605.2
#=GS MCRA_METKA/319-444        DR PDB; 1E6V A; 319-444;
#=GS MCRA_METKA/319-444        DR PDB; 1E6V D; 319-444;
#=GS A0A150IVI7_9EURY/320-446  AC A0A150IVI7.1
#=GS A0A1I4S1G7_9EURY/331-463  AC A0A1I4S1G7.1
#=GS A0A1D2WJY0_9EURY/316-442  AC A0A1D2WJY0.1
#=GS A0A0P8CBK4_9EURY/327-453  AC A0A0P8CBK4.1
#=GS A0A1V6N4K9_9EURY/316-441  AC A0A1V6N4K9.1
#=GS A0A0E3NNS2_9EURY/330-461  AC A0A0E3NNS2.1
#=GS M9SBG6_METAX/319-446      AC M9SBG6.1
#=GS A0A101IGB4_9EURY/262-388  AC A0A101IGB4.1
#=GS G7WN24_METH6/324-450      AC G7WN24.1
#=GS MCRX_METFV/319-444        AC Q49174.2
#=GS A0A139CTB8_9EURY/331-463  AC A0A139CTB8.1
#=GS A0A0E3SNQ2_METBA/329-461  AC A0A0E3SNQ2.1
#=GS I7KDB2_METBM/326-459      AC I7KDB2.1
#=GS L0HD22_METFS/328-461      AC L0HD22.1
#=GS A0A2I0P8G2_9EURY/326-345  AC A0A2I0P8G2.1
#=GS A0A1F2P729_9EURY/319-445  AC A0A1F2P729.1
#=GS A0A2A2HEG1_9EURY/322-447  AC A0A2A2HEG1.1
#=GS A0A1E7GGH8_9EURY/330-462  AC A0A1E7GGH8.1
#=GS A0A0E3SA85_9EURY/329-461  AC A0A0E3SA85.1
#=GS M4YK22_THEXX/317-444      AC M4YK22.1
#=GS A2STR9_METLZ/326-459      AC A2STR9.1
#=GS A0A166CWD2_9EURY/316-442  AC A0A166CWD2.1
#=GS A0A0P9HYI1_9ARCH/370-498  AC A0A0P9HYI1.1
#=GS A0A1D3L4K2_9EURY/316-442  AC A0A1D3L4K2.1
#=GS I7LMP5_METBM/326-459      AC I7LMP5.1
#=GS A0A2I0P7B3_9EURY/345-471  AC A0A2I0P7B3.1
#=GS A0A166CHN2_9EURY/316-442  AC A0A166CHN2.1
#=GS A0A1F2P6A2_9EURY/319-445  AC A0A1F2P6A2.1
#=GS A0A150J3N1_9EURY/320-446  AC A0A150J3N1.1
#=GS A0A0Q4BCJ2_9EURY/309-436  AC A0A0Q4BCJ2.1
#=GS A0A0E3NU58_9EURY/330-461  AC A0A0E3NU58.1
#=GS E1RDX4_METP4/326-459      AC E1RDX4.1
#=GS W9DZJ0_METTI/331-463      AC W9DZJ0.1
#=GS A0A166B5P3_9EURY/318-442  AC A0A166B5P3.1
#=GS K4MC35_9EURY/331-463      AC K4MC35.1
#=GS A0A166C196_9EURY/316-442  AC A0A166C196.1
#=GS A0B6N6_METTP/324-450      AC A0B6N6.1
#=GS A0A1D2WBA8_9EURY/316-441  AC A0A1D2WBA8.1
#=GS MCRX_METJA/318-443        AC Q60391.1
#=GS A0A2I0PSL8_9EURY/326-452  AC A0A2I0PSL8.1
#=GS MCRA_METTH/316-441        AC O27232.3
#=GS A3CT46_METMJ/326-459      AC A3CT46.1
#=GS F0T8R3_METLA/316-441      AC F0T8R3.1
#=GS A0A2I0P4I0_9EURY/1-129    AC A0A2I0P4I0.1
#=GS Q6LWZ5_METMP/319-444      AC Q6LWZ5.1
#=GS A0A1F2P9A1_9EURY/327-452  AC A0A1F2P9A1.1
#=GS R9TAZ9_METII/316-442      AC R9TAZ9.1
#=GS Q8THH1_METAC/329-461      AC Q8THH1.1
#=GS F6D2D3_METPW/316-442      AC F6D2D3.1
#=GS F6BBJ2_METIK/317-442      AC F6BBJ2.1
#=GS A0A150J824_9EURY/320-446  AC A0A150J824.1
#=GS J0SAE9_9EURY/326-459      AC J0SAE9.1
#=GS A3CSG1_METMJ/326-459      AC A3CSG1.1
#=GS U6EEP1_9EURY/316-441      AC U6EEP1.1
#=GS F7XL13_METZD/331-463      AC F7XL13.1
#=GS E3GZ51_METFV/319-445      AC E3GZ51.1
#=GS Q2FSN0_METHJ/325-458      AC Q2FSN0.1
#=GS MCRA_METJA/318-444        AC Q58256.2
#=GS A5ULZ2_METS3/316-442      AC A5ULZ2.1
#=GS A0A1F2P8K6_9EURY/388-514  AC A0A1F2P8K6.1
#=GS A0A1D2W9L6_9EURY/318-442  AC A0A1D2W9L6.1
#=GS Q8PXH8_METMA/329-461      AC Q8PXH8.1
#=GS B8GE93_METPE/325-451      AC B8GE93.1
#=GS A0A150JIY1_9EURY/320-446  AC A0A150JIY1.1
#=GS F6BE97_METIK/318-444      AC F6BE97.1
#=GS D7E8X7_METEZ/332-464      AC D7E8X7.1
#=GS A0A059TIR1_9EURY/318-445  AC A0A059TIR1.1
#=GS A0A2I0NM52_9EURY/1-64     AC A0A2I0NM52.1
#=GS A0A166A6T9_9EURY/316-442  AC A0A166A6T9.1
#=GS MCRA_METBF/329-461        AC P07962.3
#=GS MCRA_METBF/329-461        DR PDB; 1E6Y D; 4329-4461;
#=GS MCRA_METBF/329-461        DR PDB; 1E6Y A; 1329-1461;
#=GS A0A2I0P7B3_9EURY/326-347  AC A0A2I0P7B3.1
#=GS A0A0E3S2W5_9EURY/330-462  AC A0A0E3S2W5.1
#=GS D1YVW6_METPS/323-448      AC D1YVW6.1
#=GS A0A1Q6DVQ2_9EURY/317-443  AC A0A1Q6DVQ2.1
#=GS A0A0A7LF46_9EURY/319-446  AC A0A0A7LF46.1
#=GS D7DUH5_METV3/319-444      AC D7DUH5.1
#=GS MCRX_METTH/318-443        AC P21110.3
#=GS Q12TF8_METBU/331-463      AC Q12TF8.1
#=GS A0A120K0D9_9EURY/316-442  AC A0A120K0D9.1
#=GS A0A1F2PC64_9EURY/319-445  AC A0A1F2PC64.1
#=GS A0A219ALM7_9EURY/316-441  AC A0A219ALM7.1
#=GS R9SLW2_9EURY/316-442      AC R9SLW2.1
#=GS Q2NHZ8_METST/318-443      AC Q2NHZ8.1
#=GS H1YXH9_9EURY/326-459      AC H1YXH9.1
#=GS L0HIJ7_METFS/327-453      AC L0HIJ7.1
#=GS D5VQU8_METIM/318-444      AC D5VQU8.1
#=GS A0A0U2L5Y3_9EURY/318-442  AC A0A0U2L5Y3.1
A0A1D2X2N6_9EURY/318-443             ...DQVWLGSYMSGG.VGFTQY.ATAA.YTDEILDDFIYYGKDY.VENKF.......GGLC.....Q.....AEA.TSDVVRDIASEVTLYGLEQYE-IPAALEDHFGGSQRAAVLAAGAGCSVAFATANSNA.G.V.N.G.W.YLSQLLHKEGHSRL...
A0A0P9E1V1_9ARCH/368-495             say---WFGFYMSGG.IGFTNT.TAGA.ALGEASETFQEELAEL.SNKYA.......ADID.....R.....VPP.RWDVVRFIVDMIIQYAMETYEKIPALTEFHWGGAHRISLIGSLGAGTAALLTGDSTM.G.L.W.GsH.YAIALAMKEGWLR-t..
E1RJD5_METP4/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IGDKYnvdwknpSPSD.....K.....IKP.TQDIVNDIATEVCLNAMEQYEQFPTMMEDHFGGSQRAGVMAAACGLSTSIATGNSNA.G.L.N.A.W.YLCMLMHKDGWSRL...
F0TCV5_METLA/317-441                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFLYYGKEY.VEDKF.......-GLC.....G.....VKA.DADVVKDISSEITLYAMEQYE-IPALLEDHFGGSQRACVAAAAAGCSTAFATGNSNA.G.I.N.G.W.YLSQILHKEVHSRL...
A0A0P6VHH7_9EURY/330-462             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNVYYDVDY.INDKYnga.anvGKDN.....K.....IKA.TLDVVKDIATESTIYGIETYEKFPTALEDHFGGSQRATVLAAAAGVATALATSNANA.G.L.S.G.W.YLSMYLHKEAWGRL...
A0A1D2WLQ3_9EURY/318-442             ...DQVWLGSYMSGG.VGFTQY.ASAA.YTDDILDDFLYYGKDY.VEKKY.......-GMC.....Q.....ADL.SMDTVRDISTEVTLYGLEQYE-TPTLLETHFGGSQRASVVSAAAGCSTAFATGNSNA.G.V.N.G.W.YLSMILHKETHSRL...
A7I5T9_METB6/326-452                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDYCYYGLDY.VKKNH.......GGLG.....K.....AKL.TQEAVSDIASEVTLYGMEQYEQYPTALEDHFGGSQRASVLAAASGISASLGTFNSNA.G.L.N.A.W.YQSMLLHKEGWSRL...
A0A062V7W6_9EURY/331-457             ...DQIWLGGYMSGG.VGFTMY.ATPA.YTNDILDDYVYWGADY.AQKKY.......GKFG.....S.....AKA.TIETVKDIGTEVTLYGIEAYEKYPTTLEDHFGGSQRATVLAIAAGASTAMATGHSNA.G.L.S.A.W.YLSMYLHKEAWGRL...
A0A0W7TIP2_9EURY/319-446             ...DQIYLGGYMSGG.VGFTQY.ASAA.YTDNILEDYVYHGIDV.INDRY.......GGFC.....G.....IKPdDYDKQMKLGDEISSYALEMYERYPAVMETHFGGSQRATVTAASTGIVGAFATGVADN.G.L.N.L.W.YQSMLQHKERTGRL...
Q0W339_METAR/322-447                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFCYYGYDY.IKGKY.......-GIA.....K.....AKP.TMDVVNDIGTEVTLYGIEQYEKYPTTLEDHFGGSQRATVLSAAAGVTTSLATGNANA.G.L.S.A.W.YLSMYLHKEAWGRL...
F4BXY1_METSG/324-450                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNDVLDDFSYYGVDY.ANDKF.......GGFA.....K.....APA.TIDVAKELATEVTLYGIEQYEAFPTLLEDHFGGSQRAAVLAAASGITSAIATGHSQI.G.L.A.G.W.YLSMLLHKEAWGRL...
A2SSD1_METLZ/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFVYSGMDY.IHDKYkvdlknpNPND.....K.....VKA.TQEVVNDIATEVNLYGMEQYEQFPTMMEDHFGGSQRAAVLAAASGITTSIATGNSNA.G.L.N.G.W.YLSMLLHKDGWSRL...
L0L0H0_METHD/330-462                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNNILDDNLYYNVDY.INDKYnga.akkGTDN.....K.....VKA.TLEVVKDIATESTLYGMENYEKYPTALEDHFGGSQRATVLSAAAGAATAIATGNGNA.G.L.S.G.W.YLSMYLHKEGHGRL...
A0A1F2PDF7_9EURY/495-624             dig---YLHNYLAGGsSGWTQVmITQG.YCSDIDNDFCYRTLDAdTMTHF.......MGLD.....F.....APT.SMDSLYTATEGIVKYGMEYFDKMPIAQETLYGGLQRAALISAVGGASTAYFCRTPTF.G.L.P.G.F.YHGLLLCKEGWNRL...
A5ULM9_METS3/318-442                 ...DQVWLGSYMSGG.VGFTQY.ASAT.YTDDILDDFVYYGLDY.VEDNY.......-GLC.....Q.....AEK.TMDVVRDISTEVTLYGLEQYE-IPTLLETHFGGSQRASVISAAAGCSTAFATANSNA.G.V.N.G.W.YLSMLLHKEGHSRL...
A0A1F2P3I8_9EURY/318-445             .gl--IWFDSYVLGG.IGGANT.FSSP.FTNNLLDDFAYHISDW.VKDRY.......GGLA.....S.....ARP.SFEVVKEVTEEVNFYGMEQYDTYPLLLEHHWGGVIRLLNLNAASAIGVGFATGNSTA.A.L.L.AvY.YSGAFIQKEAWGR-h..
A0A1Y3GED3_9EURY/319-445             ...DQLYLGGYMSGG.VGFTQD.GCCH.YTDDILDDFVYYGKEL.VVDRF.......GEVG.....S.....APV.NLDVVSELATEVNDYALGCYEDFPSAMETHFGGSQRAAIGGIAAGVTVGLATGHSQA.G.L.S.G.W.FLSQNQHKERCGRL...
A0A0U3E6Z6_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFTYYGKDY.VEDKY.......GDLC.....S.....APN.NMDTVLDVGTEVAFYALDQYEEYPALLETHFGGSQRASVISAAAGCSTAFATGNAQT.G.L.S.A.W.YLAMYLHKEQHSRL...
U6EF81_9EURY/317-441                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFLYYGMEY.VDDKY.......-GLC.....G.....TKA.TTEVVHDIASEVTMYGLEQYE-YPALMEDHFGGSQRTAVVSAAAGCSVAFATGNSNA.G.I.N.G.W.YLSQILHKEAHSRL...
A0A124G584_9EURY/326-459             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwqnpSPND.....K.....VKP.TQEIVNDIATEVNLNGMEQYEQYPTMMEDHFGGSQRAGVLAAACGLSTAIATGNSNA.G.L.N.G.W.YLSMLMHKEGWSRL...
A6UWH2_META3/318-443                 ...DQIWLGAYMSGG.VGFTQY.ATAA.YTDDILDDFCYYGLDY.VEKKF.......-GRC.....G.....TKA.TMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGGSQRAAVAAAAAGVSVCMATGNSNA.G.V.N.G.W.YLSQIMHKEYHSRL...
J0RY59_9EURY/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwkhpNAAD.....K.....VKP.TQDVVNDIATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLSTAIATGNSNA.G.L.N.G.W.YLSMLMHKEGWSRL...
D5EAD6_METMS/332-464                 ...DQIWLGSYMSGG.VGFTQY.STAA.YTNNILDDNLYYDVEY.INDKYdga.aekGIDN.....K.....VAP.SMDVIKDIATESTLYGLENYEKYPVALEDHFGGSQRATVLSAAAGSAGSLATGNANA.G.L.S.A.W.YLCMYLHKEGHGRL...
A0A0F8E165_9EURY/330-462             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNVYYDVDY.INDKYnga.anlGKDN.....K.....VKA.TLEVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAAAGVATSLATANANA.G.L.S.G.W.YLSMYLHKEAWGRL...
A0A1Y3GE24_9EURY/318-444             ...DQLYLGGYMSGG.VGFTQY.ATAT.YTDDILDDFVYHGAEL.IDEKF.......GGLG.....N.....VEP.TMENVEEIATEMTDYSLSAYEDYPAAMEAHFGGSQRAAVVAASAGVAASMATGNANA.G.V.N.G.W.YLSQLLHKERAGRL...
A0A1F2P3F1_9EURY/327-453             ..f-QLYYGQMMIGT.VGATVA.PATF.YVNDLYESRGYYLTDW.IRKKY.......GEFA.....S.....APM.NWDTIHDCAEEATMHCLEEYDIYPLLPEHHWGLIHAIQI-SISASACAAWATGNSMA.AaL.A.A.H.HSMTLIQKESI---lrt
D3E050_METRM/315-441                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFSYFGKDY.VEDKY.......GDLC.....S.....APN.DMDTVLDVGSAVTFYSLEQYEEYPALLETHFGGSQRAAVVSAASGISTAFATGNAQT.G.L.S.A.W.YLAQYLHKEQHSRL...
MCRA_METKA/319-444                   ...DQIWLGSYMSGG.VGFTQY.ATAV.YTDNILDDYVYYGLEY.VEDKY.......-GIA.....E.....AEP.SMDVVKDVATEVTLYGLEQYERYPAAMETHFGGSQRAAVCAAAAGCSTAFATGHAQA.G.L.N.G.W.YLSQILHKEGHGRL...
#=GR MCRA_METKA/319-444        SS    ...HIIIIIIISS-S.S--HHH.HHTT.SBTTHHHHHHHHHHHH.HHHHS.......--TT.....T.....S--.-HHHHHHHHHHHHHHHHHHHHH-HHHHHHS-SHHHHHHHHHHHHHHHHHHHH--HHH.H.H.H.H.H.HHHHHHHHHHHT--...
A0A150IVI7_9EURY/320-446             ...DQIYLGSYMSGG.VGFTQY.ATAA.YTDNILEDFVYWGMEH.VKDKY.......GDLA.....K.....QKP.SVKLINEIGTDVAMYCLEQYELYPAVMETHFGGSQRATCISAAAGTSVSMATGNAQA.G.L.S.A.W.YLACNIHKEQMGR-f..
A0A1I4S1G7_9EURY/331-463             ...DQIWLGSYMSGG.VGFTQY.ATAA.YCNNILDDNLYYNVDY.INDKYdga.attGTDN.....K.....IKA.DLEVVKDIATESTIYGLENYEKYPTTLEDHFGGSQRATSLSAAAGSAVSLATGNGNA.G.L.S.G.W.YLCMYLHKEAHGRL...
A0A1D2WJY0_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFTYYGKDY.VEDKY.......GDLC.....A.....APN.NMDTVLDVGSEVAFYALDQYEEYPALLETHFGGSQRASVISAAAGCSTAFATGNAQT.G.L.S.G.W.YLSMYLHKEQHSRL...
A0A0P8CBK4_9EURY/327-453             ...DQIWLGGYMSGG.VGFTMY.ATPA.YTNDIVDDFLYWADEY.ASKKY.......GGRG.....K.....AKA.TIDTVKDIATESTLYSLEAYEKYPTTLEDHFGGSQRATVCSIAAGGATALATGHSQA.G.L.S.A.W.YLSMYLHKEAHGRL...
A0A1V6N4K9_9EURY/316-441             ...DQIWLGSYMSGG.VGFTQY.ASAA.YTDNILDDFLYYGKEY.VEDKF.......-GIC.....E.....APN.NMDTVLDVGSEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGCATAFATGNSQT.G.L.S.A.W.YLSMYLHKEQHSRL...
A0A0E3NNS2_9EURY/330-461             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDVLDNNTYYDVDY.INDKY.......NGAA.....EvgqptVKA.SLDVVKDIATESTIYGIETYEKFPTALEDHFGGSQRATVLAAASGVACALATGNGNA.G.L.S.G.W.YLSMYVHKEAWGRL...
M9SBG6_METAX/319-446                 ...DQVYLGGYMSGG.VGFTQY.ATAA.YTDNILEDYVYHAVDV.INDRY.......GGFC.....G.....VAPdDYDKQLKLGDEISSYALEMYERYPAVMETHFGGSQRATVTAASTGIAGAMATGVADN.G.L.N.L.W.YQSMLQHKERTGRL...
A0A101IGB4_9EURY/262-388             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNDVLDDFSYYACDY.GVDKF.......GGWG.....E.....APA.TLETSKDIATETTLYAMEQYEAFPTLLEDHFGGSQRSAVMAAASAIGSACLTGNSQS.G.L.A.G.W.YLSHLIHKDGWGRM...
G7WN24_METH6/324-450                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNDVLDDFSYYACDY.GVDKF.......GDWG.....K.....APA.TLETSKDIATETTLYAMEQYESFPTLLEDHFGGSQRSAVMAAASAIGSACLTGNSQS.G.L.A.A.W.YLSHLIHKDGWGRM...
MCRX_METFV/319-444                   ...DQVWLGSYMSGG.VGFTQY.ASAT.YTDDILDDFVYYGAEY.VEDKY.......-GFC.....G.....VKP.SMEVVKDIATEVTLYGLEQYEEYPTLLEDHFGGSQRAAVVAAAAGCSTAFATGNSNA.G.I.N.A.W.YLSQILHKEGHSRL...
A0A139CTB8_9EURY/331-463             ...DQIWLGSYMSGG.VGFTQY.ATAA.YCNNILDDNLYYNVDY.INDKYdga.ankGTDN.....K.....IAA.NLDVVKDIATESTIYGLENYEKYPTTLEDHFGGSQRATSLSAAAGSAVSIATGNGNA.G.L.S.G.W.YLSMYLHKEALGRL...
A0A0E3SNQ2_METBA/329-461             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNVYYDVDY.INDKYnga.anvGKDN.....K.....VKA.TLEVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAAAGVATSLATANANA.G.L.S.G.W.YLSMYLHKEAWGRL...
I7KDB2_METBM/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwknpSAND.....K.....VKP.TYDIVNDMATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTAIATGNSNA.G.L.N.G.W.YLSMLLHKDGWSRL...
L0HD22_METFS/328-461                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFTYYGMDY.VKDKYgynfrqpGADK.....V.....IRP.TQDIVNDIATEVTLYSMEQYEKFPTLMEDHFGGSQRAAVMAAAAGLSTSITTGNSNA.G.L.N.A.W.YLSMIIHKDGWSRL...
A0A2I0P8G2_9EURY/326-345             ...DQIWLGSYMSGG.VGFTQY.AT--.----------------.-----.......----.....-.....---.---------------------------------------------------------.-.-.-.-.-.--------------...
A0A1F2P729_9EURY/319-445             .ly---WFSSYVVGG.IGGPNT.FASP.FTSELLTDFTYHISDW.VKEKY.......GGYV.....A.....CKP.SFDVIREVTEEVNFYAMEQYDKYPLLLEHHWGGVIRILNLNAASAIGVGFATGNSTAaS.I.A.N.Y.YSGGFLQKEAWGR-n..
A0A2A2HEG1_9EURY/322-447             ...DQVWLGSYMSGG.VGFTQY.ATAA.YTDEILDDFVYYGKEY.VETKY.......GGLA.....Q.....TEA.TTDVVRDIASEVTLYGLEQYE-IPAALEDHFGGSQRAAVLAAGAGCSVAFATANSNA.G.L.N.G.W.YLSQLLHKEGHSRL...
A0A1E7GGH8_9EURY/330-462             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNVYYNVDY.INDKYkga.atiGTGN.....K.....VKA.TLDVVKDIATESTIYGIETYEKFPTALEDHFGGSQRATVLAAAAGVACALATANANA.G.L.S.G.W.YLSMYLHKEAWGRL...
A0A0E3SA85_9EURY/329-461             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNVYYDVDY.INDKYnga.anvGKDN.....K.....IKA.TLEVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAAAGVACALGTANANA.G.L.S.G.W.YLSMYLHKEAWGRL...
M4YK22_THEXX/317-444                 ...DQIYLGGYMSGG.VGFTQY.ATAA.YTDNILEDYVYHAVDI.IKDKY.......GGFC.....G.....VKAdDYKKQLQLGDEISSYALEMYERYPAVMETHFGGSQRATVTAASTGIAGAMATGVADN.G.L.N.L.W.YQSMLQHKERTGRL...
A2STR9_METLZ/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFTYYGMDY.IHDKYkvdiknpNPKD.....K.....VKA.TQEVVNDIATEVNLYGMEQYEQFPTMMEDHFGGSQRAAVLAAASGITTSIGTGNSNA.G.L.N.G.W.YLSMLMHKDGWSRL...
A0A166CWD2_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ASAA.YTDNVLDDFTYYGKEY.VEDKY.......GGLC.....E.....APN.NMDTVLDVGSEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGCSTAFATGNAQT.G.L.S.A.W.YLSMYLHKEQHSRL...
A0A0P9HYI1_9ARCH/370-498             ..n-MIWLGFYMSGG.IGFSNT.VSAAgLAGGVIEDITEELIET.THRYI.......RGIK.....K.....VPP.KWDIVRFIVDMIIQYVMESYEKFPALSEFHWGGAHKVSIIGSMGAGVASLLTGSSTM.G.MwA.G.H.YAIALVMKEGWLR-t..
A0A1D3L4K2_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.GTAA.YTDNILDDFCYYGKEY.VEDKF.......GGLC.....E.....APN.NMDTVRDVGSEVTFYGLEQYEEYPALLETQFGGSQRAAVAAAAAGCSTGFATGNAQT.G.L.S.A.W.YLSMYLHKEQHARL...
I7LMP5_METBM/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwknpSAKD.....K.....IKP.TQDVVNDMATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTAIATGNSNA.G.L.N.G.W.YLSMLLHKDGWSRL...
A0A2I0P7B3_9EURY/345-471             ..t--------MSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwknpSPSD.....K.....VKP.TYDVVNDMATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSIATGNSNA.G.L.N.A.W.YLSMLLHKDGWSRL...
A0A166CHN2_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ASAA.YTDNVLDDFCYYGKEY.VEDKY.......GGLT.....K.....APN.NMDTVLDVGTEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGISTAFATGNSQT.G.L.S.A.W.YLSMYLHKEQHSRL...
A0A1F2P6A2_9EURY/319-445             ..n--LWVNGYVIGG.IGGVNA.GAVI.FTNNVLDEFAKHVADW.IIERY.......GGFA.....R.....AKP.SFDVIRDVCHEACFHVLEEYNRYPLLLEHHWGGAIRMFVLSILGGMGPSFATGHSLA.G.M.I.G.YhYVGGYLMKEAWGR-g..
A0A150J3N1_9EURY/320-446             ...DQIYLGSYMSGG.VGFTQY.ATAA.YTDNILEDFVYWGMEH.VKDKY.......GDLA.....K.....QKP.SVKLINDIGTDVAMYCLEQYELYPAVMETHFGGSQRATCISAAAGTSVSMATGNAQA.G.L.S.A.W.YLACNIHKEQMGR-f..
A0A0Q4BCJ2_9EURY/309-436             ...DQIYLGGYMSGG.VGFTQY.ASAA.YTDNILEDYVYYAIDT.IKDKY.......GGFC.....K.....LDPnNYDKLMELGDNVNTYALEMYERYPAAMEAHFGGSQRATVAAAATGIAGSMATGNADC.G.V.N.M.W.YLSMLQHKERTGRL...
A0A0E3NU58_9EURY/330-461             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNTYYDVDY.INDKY.......GGAAavdkpT.....VKA.SLEVVKDIATESTLYGIETYENYPTALEDHFGGSQRATMLAAASGVACSLATGNGNA.G.L.S.G.W.YLSMYVHKEAWGRL...
E1RDX4_METP4/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.LKDKYsvdytnpDPAK.....L.....IKP.TQEVVNDLATEVNLNAMEQYEQYPTMMEDHFGGSQRAGVMAAACGLTCSIGTGNSNA.G.L.N.G.W.YLSMLMHKEGWSRL...
W9DZJ0_METTI/331-463                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YCNNILDDNLYYNVDY.INDKYdga.attGTDN.....K.....VKA.NLEVVKDIATESTIYGLENYEKYPTTLEDHFGGSQRATSLSAAAGSAVSLATGNGNA.G.L.S.G.W.YLCMYLHKESHGRL...
A0A166B5P3_9EURY/318-442             ...DQVWLGSYMSGG.VGFTQY.ASAT.YTDDILDDFVYYGMDY.VEKNY.......-GLC.....G.....AEK.SMDVVRDISTEVTLYGLEQYE-LPTLLETHFGGSQRASVVSAAAGCSTAFATGNSNA.G.V.N.G.W.YLSMILHKEAHSRL...
K4MC35_9EURY/331-463                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNNILDDNLYYDVDY.INDKYdga.aktGKDN.....K.....VKA.TLEVVKDIATESTIYGLENYEKYPTTLEDHFGGSQRATSLSAAAGCATAIATGNGNA.G.L.S.A.W.YLSMYLHKEAHGRL...
A0A166C196_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFTYFGKDY.VEDKY.......GGLT.....Q.....APN.NMDTVLDVGTEVAFYALEQYEEYPALLETHFGGSQRSSVISAAAGASTAFATGNAQT.G.L.S.A.W.YLSMYLHKEQHSRL...
A0B6N6_METTP/324-450                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNDVLDDFSYYGVDY.AVEKY.......GGFA.....K.....APA.NLEVVKDLATEVTLYALEQYESFPTLLEDHFGGSQRAGVTAAASGITCAIATGNSQA.G.L.A.G.W.YLSQLLHKEAHGRL...
A0A1D2WBA8_9EURY/316-441             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFTYFGKEY.VEDKY.......-GMT.....E.....APN.TMETVLDVASEVTFYGLEQYEEYPALLEDQFGGSQRAAVTAAAAGCSTAFATGNAQT.G.L.S.G.W.YLSMYLHKEQHSRL...
MCRX_METJA/318-443                   ...DQVWLGSYMSGG.VGFTQY.ASAT.YTDDILDDFVYYGMDY.VEKKY.......-GLC.....G.....VKP.SMEVVKDIATEVTLYGLEQYDEYPALLEDHFGGSQRAGVTAAAAGCSVAFATGNSNA.G.I.N.G.W.YLSQILHKEYHSRL...
A0A2I0PSL8_9EURY/326-452             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDYCYYGLDY.IKSKH.......GGLG.....K.....AKK.SQDVINDIATEVTLYGMEQYEQYPTTLEDHFGGSQRASVLAAASGISCSLATANSNA.G.L.N.G.W.YMSMLAHKEGWSRL...
MCRA_METTH/316-441                   ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFTYFGKEY.VEDKY.......-GLC.....E.....APN.TMDTVLDVASEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATANAQT.G.L.S.G.W.YLSMYLHKEQHSRL...
A3CT46_METMJ/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwknpSADD.....K.....VKP.TYDTVNDIATEVALNGMEQYEQYPTMMEDHFGGSQRAGVLAAACGLSSSIATGNSNA.G.L.N.A.W.YLCMLLHKDGWSRL...
F0T8R3_METLA/316-441                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFVYYGKEY.VEDKF.......-GMT.....E.....APN.NMDTVLDVGSEVTFYALEQFEEYPALLETIFGGSQRASIVAAAAGASTGFATGNAQT.G.L.S.A.W.YLSMYLHKEQHSRL...
A0A2I0P4I0_9EURY/1-129               ...-----GSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.AKDKYkvdwknpSPSD.....K.....VKP.TQEIVNDLATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSITTGNSNA.G.L.N.A.W.YLSMLLHKDGWSRL...
Q6LWZ5_METMP/319-444                 ...DQIWLGAYMSGG.VGFTQY.ATAS.YTDDILDDFSYYALDY.VEKKY.......GR-M.....G.....TKA.TMDVVEDVAGEVTLYALEQYDDYPALLEDHFGGSQRAAVAAAASGIGVCMATGNSNA.G.V.N.G.W.YLSQILHKEYHSRL...
A0A1F2P9A1_9EURY/327-452             ..a--LYYGQMMIGT.VGVTVA.PATF.YVNELYESRGAHLVDW.IKDKY.......GGIA.....Q.....APM.NWDTIHDCTDEATMAAIEEYDTYPLLPEHHWGLIQAVQISLISSAC-AAWATGKPMA.GaL.A.A.H.YCMSFVQKEALMR-t..
R9TAZ9_METII/316-442                 ...DQIYLGSYMSGG.VGFTQY.ATAA.YTDNILEDYVYWAVDL.IKSQY.......GGLC.....K.....SKP.SMDLLEKLGTEVNTYALEMYEKYPAAMESHFGGSQRATVAAASTGIACAMATGNADF.G.V.N.G.W.YLSMLQHKERHGRL...
Q8THH1_METAC/329-461                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNTYYDVDY.INDKYnga.anlGTDN.....K.....VKA.TLDVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAASGVACALATGNANA.G.L.S.G.W.YLSMYVHKEAWGRL...
F6D2D3_METPW/316-442                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFCYYGKEY.VEDKF.......GGLC.....E.....APN.TMETVLDVGSEVTFYALEQYEEYPALLETQFGGSQRAAVTAAAAGCSTGFATGNAQT.G.L.S.A.W.YLSMYLHKEQHSRL...
F6BBJ2_METIK/317-442                 ...DQVWLGSYMSGG.VGFTQY.ASAT.YTDDILDDFVYYGLDY.VEKKY.......-GLC.....G.....TKP.TMDVVRDIATEVTLYGLEQYDEYPALLEDHFGGSQRAAVTAAAAGCSVAFATGNSNA.G.I.N.G.W.YLSQILHKEYHSRL...
A0A150J824_9EURY/320-446             ...DQIYLGSYMSGG.VGFTQY.ATAA.YTDNILEDFVYWGMEH.VKDKY.......GDLA.....K.....QKP.SVKLINDIGTDVAMYCLEQYELYPAVMETHFGGSQRATCISAAAGTSVAMATGNAQA.G.L.S.A.W.YLACNIHKEQMGR-f..
J0SAE9_9EURY/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwrnpSAAD.....R.....VKP.TQDIVNDIATEVTVNAMEQYEQYPTMMEDHFGGSQRAGVMAAASGLSTAIATGNSNA.G.L.N.G.W.YLSMIIHKDAWSRL...
A3CSG1_METMJ/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.AKDKYkvdwknpSPSD.....K.....VKP.TQEIVNDLATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSITTGNSNA.G.L.N.G.W.YLSMLLHKDGWSRL...
U6EEP1_9EURY/316-441                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFTYFGKEY.VEDKY.......-GIT.....E.....APN.TMDTVLDVGSEVTFYALEQFEDYPALLETIFGGSQRASIVAAAAGCSTAFATGNAQT.G.L.S.A.W.YLSMYLHKEQHSRL...
F7XL13_METZD/331-463                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNNILDDNLYYDVDY.INDKYdga.antGTDN.....K.....VKP.TLDVVKDIATESTIYGLENYEKYPTALEDHFGGSQRATVLSAAAGSATAIATGHGNA.G.L.S.A.W.YLSMYLHKEAHGRL...
E3GZ51_METFV/319-445                 ...DQIWLGSYMSGG.VGFTQY.ATAS.YTDNILDDFTYYGKEY.VEDKY.......GGLA.....E.....APH.DFDTILDVATEVTLYSLEQYEEYPTLMEDHFGGSQRAAIAAAASGCSTAFAAGNAQA.G.L.S.G.W.YLSQILHKECHARL...
Q2FSN0_METHJ/325-458                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYkvdwknpSPKD.....K.....VKP.TQEIVNDIAGEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLSVGVATANSNA.G.L.N.G.W.YLSMLMHKEGWSRL...
MCRA_METJA/318-444                   ...DQIWLGGYMSGG.VGFTQY.ATAT.YTDDILDDFSYYGYDY.ITKKY.......GGCN.....S.....VKP.TMDVVEDIATEVTLYGLEQYDTFPALLEDHFGGSQRAGVTAAAAGITTALATGNSNA.G.V.N.G.W.YLSQILHKEYHSRL...
A5ULZ2_METS3/316-442                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDVLDDFTYYGKDY.VEDKY.......GGLT.....E.....APN.NMDTVLDVGSEVSFYALEQYEEYPALLETHFGGSQRASVISAAAGCSTAFATGNAQT.G.L.S.A.W.YLGMYLHKEQHSRL...
A0A1F2P8K6_9EURY/388-514             ...DAVWYGIYMSGG.VGFPAF.AY-L.YLGNILDDWLNRFTEL.CYYNF.......EGHE.....R.....VPD.TWDCAKGFGEIAALYLMETYEKYPTLQELHWGGAIRCFITSAISNSFASLLTGDSLM.G.M.MvQ.N.YVVSLLMKEGWLR-t..
A0A1D2W9L6_9EURY/318-442             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFLYYGKEY.VEDKF.......-GLC.....Q.....AKA.DMDVVKDITTEVTLYGMEQYE-IPTLLESHFGGSQRAAVAAAAAGCSTAFATGNSNA.G.I.N.G.W.YLSQILHKEVHSRL...
Q8PXH8_METMA/329-461                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNTYYDVDY.INDKYnga.anlGTDN.....K.....VKA.TLDVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAASGVACALATGNANA.G.L.S.G.W.YLSMYVHKEAWGRL...
B8GE93_METPE/325-451                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFVYYGMDY.LKSKY.......GGYS.....Q.....APA.TQEVVNDLATEVTLNAMEQYEQFPTMMEDHFGGSQRASVIAAASGLTTSIGTGNSNA.G.L.N.G.W.YLSMLMHKEGWSRL...
A0A150JIY1_9EURY/320-446             ...DQIYLGSYMSGG.VGFTQY.ATAA.YTDNILEDFVYWGMEH.VKDKY.......GSLA.....K.....QKP.SVKLINDIGTDVAMYCLEQYELYPAVMETHFGGSQRATCISAAAGTSVSMATGNAQA.G.L.S.A.W.YLACNVHKEQMGR-f..
F6BE97_METIK/318-444                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFSYYGYDY.ITKKY.......GGCN.....S.....IKP.TMDVVEDIATEVTLYALEQYDEYPALLEDHFGGSQRAAVTAAAAGITTALATGNSNA.G.L.N.G.W.YLSQILHKEYHSRL...
D7E8X7_METEZ/332-464                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNNILDDNLYYDIEY.INDKYnna.gkpGADN.....K.....APA.TMDVVKDIATESTLYGLENYEKYPTALEDHFGGSQRATVLSAAAGSATSIATGNSNA.G.L.S.A.W.YLSMYLHKEAHGRL...
A0A059TIR1_9EURY/318-445             ...DQVYLGGYMSGG.VGFTQY.ATAA.YTDNILEDYVYHGIDT.IKDRY.......GGFC.....G.....VKPdDYKKQLKLADEISSYALEMYERYPAVMEIHFGGSQRATVTAASTGIITAMATGVADN.G.L.N.A.W.YQSMLQHKERTGRL...
A0A2I0NM52_9EURY/1-64                ...------------.------.----.----------------.-----.......----.....-.....---.------------TLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSITTGNSNA.G.L.N.G.W.YLSMLLHKDGWSRL...
A0A166A6T9_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ASAA.YTDNVLDDFAYYGKEY.VEDKY.......GGLT.....Q.....APN.NMDTVLDVGSEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGISTAFATGNSQT.G.L.S.A.W.YLSMYLHKEQHSRL...
MCRA_METBF/329-461                   ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNTYYDVDY.INDKYnga.atvGKDN.....K.....VKA.SLEVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAAAGVACSLATGNANA.G.L.S.G.W.YLSMYLHKEAWGRL...
#=GR MCRA_METBF/329-461        SS    ...HHIIIIIITS-T.T--HHH.HHCC.CBTTHHHHHHHHHHHH.HHHHTTTT.TSS-SSS.....-.....---.-HHHHHHHHHHHHHHHHHHHHH-HHHHHHT-SHHHHHHHHHHHHHHHHHHHHS-HHH.H.H.H.H.H.HHHHHHHHHHHT--...
A0A2I0P7B3_9EURY/326-347             ...DQIWLGSYMSGG.VGFTQY.ATM-.----------------.-----.......----.....-.....---.---------------------------------------------------------.-.-.-.-.-.--------------s..
A0A0E3S2W5_9EURY/330-462             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDNNTYYDVDY.INDKYkga.atiGTDN.....K.....VKA.SLEAVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAAAGVACSLATGNANA.G.L.S.G.W.YLSMYVHKEAWGRL...
D1YVW6_METPS/323-448                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFTYYGYDY.AKGKY.......-KIG.....Q.....TKP.TMDIVNDLSTEVTLYGIEQYEKYPTTLEDHFGGSQRATVLSAAAGVTTAIATGNSNA.G.L.S.G.W.YMSMYLHKEAWGRL...
A0A1Q6DVQ2_9EURY/317-443             ...DQLYLGGYMSGG.VGFTQY.ATAT.YTDNILEDYVYHGVDL.LEEKY.......GGLG.....Q.....ADT.TMEDVEDIATEMTDYALSEYENYPAAMETHFGGSQRAAVTAASAGVTTAMATGNSNA.G.V.N.G.W.YLSQLLHKERLGRL...
A0A0A7LF46_9EURY/319-446             ...DQVYLGGYMSGG.VGFTQY.ASAT.YTDNILEDYVYHAVDV.IKDKY.......GGLC.....K.....LDPsKYDELMKLGDDVNAYALEMYEKYPAIMETHFGGSQRATVAAATTGIAGSMATGIADC.G.L.N.M.W.YLSMLQHKERTGRL...
D7DUH5_METV3/319-444                 ...DQIWLGSYMSGG.VGFTQY.ATAS.YTDDILDDFSYYGLDY.VEKKY.......-GRC.....G.....TKA.TMDVVEDIASEVTLYALEQYDEYPALLEDHFGGSQRAAVAAAAAGISTCMATGNSNA.G.V.N.G.W.YLSQILHKEYHSRL...
MCRX_METTH/318-443                   ...DQVWLGSYMSGG.VGFTQY.ATAA.YTDDILDDFVYYGMEY.VDDKY.......-GIC.....G.....TKP.TMDVVRDISTEVTLYSLEQYEEYPTLLEDHFGGSQRAAVAAAAAGCSTAFATGNSNA.G.I.N.G.W.YLSQILHKEAHSRL...
Q12TF8_METBU/331-463                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTNNILDDNLYYNVDY.INDKYdga.ankGADN.....K.....VKA.TMDVVKDIATESTIYGIENYEKYPTALEDHFGGSQRATVLSAAAGSATALATGNGNA.G.L.S.G.W.YLSMYLHKEALGRL...
A0A120K0D9_9EURY/316-442             ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFTYYGKDY.VEDKY.......GDLC.....S.....APN.NMDTVLDVGSEVAFYALEQYESYPALLETHFGGSQRASVISAAAGCSTAFATGNAQT.G.L.S.A.W.YLSMYLHKEQHSRL...
A0A1F2PC64_9EURY/319-445             ..h--MWVNSYVLGG.IGGVNA.GAVI.YTNNVLEEETNYIADW.IKDRY.......GGFA.....M.....AKP.SFDVIRDVTHEMTFHLMEEYNRYPLLLEHHWGGAQRVVMLSTLAGLSSGLATGHSLA.G.M.I.G.YnYAQAYLMKEAWGR-g..
A0A219ALM7_9EURY/316-441             ...DQVWLGSYMSGG.VGFTQY.ATAA.YTDNVLDDFAYYGKDY.VEDKY.......-GLT.....E.....APN.NMDTVLDVGSEVTFYGLEQYEKFPALLETQFGGSQRAAVTAAAAGISTAFATGNAQT.G.L.S.A.W.YLSQYLHKEQHSRL...
R9SLW2_9EURY/316-442                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFAYYGKDY.VEDKY.......GGLT.....E.....APN.NMDTVLDVGSEVTFYALEQYDEYPALLETQFGGSQRAAVTAAASGCCTAFATGNSQT.G.L.S.A.W.YLSQYLHKEQHSRL...
Q2NHZ8_METST/318-443                 ...DQVWLGSYMSGG.VGFTQY.ATAA.YTDEILDDFIYYGKDY.VEGKY.......GGLC.....Q.....AEA.TSEVVKDIASEVTLYGLEQYE-IPAALEDHFGGSQRAAVLAAGAGCSVAFATANSNA.G.V.N.G.W.YLSQLLHKEGHSRL...
H1YXH9_9EURY/326-459                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDEFTYYGMDY.IKDKYgvdytnpDPAK.....L.....VKP.TQEVVNDIASEVNLNAMEQYEQFPTMMEDHFGGSQRAGVMAAACGLSTSIATGNSNA.G.L.N.G.W.YLSMLMHKEGWSRL...
L0HIJ7_METFS/327-453                 ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDNILDDFTSYGVDY.VKKKH.......GALG.....K.....VKA.TQDVVNDIASEVTLYGMEQYEEFPTTLESHFGGSQRATVLAAASGVSTALATANSNA.G.L.N.G.W.YMSMLMHKEAWSRL...
D5VQU8_METIM/318-444                 ...DQIWLGSYMSGG.VGFTQY.ATAS.YTDDILDDFSYYGYDY.INKKY.......GGCN.....S.....VKP.TMDVVEDIATEVTLYALEQYDTYPALLEDHFGGSQRAAVTAAASGISVALATGNSNA.G.L.N.G.W.YLSQILHKEYHSRL...
A0A0U2L5Y3_9EURY/318-442             ...DQVWLGSYMSGG.VGFTQY.ASAA.YTDDILDDFIYYGMDY.VEKNY.......-GMC.....N.....AEL.DMDTVRDISTEVTLYGLEQYE-IPTLLETHFGGSQRASVISAAAGCSTAFATGNSNA.G.V.N.G.W.YLSMILHKEAHSRL...
#=GC SS_cons                         ...HHIIIIIITS-T.T--HHH.HHCC.CBTTHHHHHHHHHHHH.HHHHTTTT.TSS-STT.....T.....S--.-HHHHHHHHHHHHHHHHHHHHH-HHHHHHT-SHHHHHHHHHHHHHHHHHHHHS-HHH.H.H.H.H.H.HHHHHHHHHHHT--...
#=GC seq_cons                        ...DQIWLGSYMSGG.VGFTQY.ATAA.YTDsILDDFsYYGhDY.lcDKY.......Guhs.....p.....scs.ohDlVpDluTEVTlYulEQYEpYPshLEcHFGGSQRAuVlAAAuGsosuhATGNusA.G.L.s.u.W.YLSMhLHKEuauRL...
//
DBGET integrated database retrieval system