GenomeNet

Database: Pfam
Entry: PF02745
LinkDB: PF02745
Original site: PF02745 
#=GF ID   MCR_alpha_N
#=GF AC   PF02745.15
#=GF DE   Methyl-coenzyme M reductase alpha subunit, N-terminal domain
#=GF AU   Mian N;0000-0003-4284-4749
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE   Pfam-B_2706 (release 5.2)
#=GF GA   20.50 20.50;
#=GF TC   20.50 32.30;
#=GF NC   18.60 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9367957
#=GF RT   Crystal structure of methyl-coenzyme M reductase: the key enzyme
#=GF RT   of biological methane formation 
#=GF RA   Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK; 
#=GF RL   Science 1997;278:1457-1462.
#=GF DR   INTERPRO; IPR003183;
#=GF DR   SCOP; 1mro; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Methyl-coenzyme M reductase (MCR) is the enzyme responsible for 
#=GF CC   microbial formation of methane. It is a hexamer composed of 2
#=GF CC   alpha (this family), 2 beta (Pfam:PF02241), and 2 gamma
#=GF CC   (Pfam:PF02240) subunits with two identical nickel porphinoid
#=GF CC   active sites [1]. The N-terminal domain has a ferredoxin-like
#=GF CC   fold.
#=GF SQ   113
#=GS A0A166B5P3_9EURY/5-271    AC A0A166B5P3.1
#=GS A0A1F2P9A1_9EURY/5-276    AC A0A1F2P9A1.1
#=GS Q8THH1_METAC/14-282       AC Q8THH1.1
#=GS MCRA_METBF/14-282         AC P07962.3
#=GS MCRA_METBF/14-282         DR PDB; 1E6Y D; 4014-4282;
#=GS MCRA_METBF/14-282         DR PDB; 1E6Y A; 1014-1282;
#=GS A0A101IGB4_9EURY/36-214   AC A0A101IGB4.1
#=GS Q8TVA5_METKA/8-60         AC Q8TVA5.1
#=GS Q12TF8_METBU/14-283       AC Q12TF8.1
#=GS A0A059TIR1_9EURY/6-270    AC A0A059TIR1.1
#=GS A0A150JIY1_9EURY/7-272    AC A0A150JIY1.1
#=GS H1YXH9_9EURY/8-278        AC H1YXH9.1
#=GS A0A1Y3GE24_9EURY/5-270    AC A0A1Y3GE24.1
#=GS L0L0H0_METHD/13-282       AC L0L0H0.1
#=GS W9DZJ0_METTI/14-283       AC W9DZJ0.1
#=GS A0A0P9HYI1_9ARCH/41-306   AC A0A0P9HYI1.1
#=GS A0A1D2W9L6_9EURY/5-271    AC A0A1D2W9L6.1
#=GS R9SLW2_9EURY/3-268        AC R9SLW2.1
#=GS A0A1D2WJY0_9EURY/3-268    AC A0A1D2WJY0.1
#=GS E3GZ51_METFV/6-271        AC E3GZ51.1
#=GS A0A1F2P8K6_9EURY/59-323   AC A0A1F2P8K6.1
#=GS A0A2A2HEG1_9EURY/8-275    AC A0A2A2HEG1.1
#=GS A0A166CHN2_9EURY/3-268    AC A0A166CHN2.1
#=GS A3CSG1_METMJ/8-278        AC A3CSG1.1
#=GS A0B6N6_METTP/7-276        AC A0B6N6.1
#=GS D5VQU8_METIM/5-271        AC D5VQU8.1
#=GS A0A150J3N1_9EURY/7-272    AC A0A150J3N1.1
#=GS MCRX_METFV/6-272          AC Q49174.2
#=GS I7KDB2_METBM/8-278        AC I7KDB2.1
#=GS A0A1Q6DVQ2_9EURY/3-269    AC A0A1Q6DVQ2.1
#=GS MCRX_METTH/4-271          AC P21110.3
#=GS A0A2I0P8G2_9EURY/8-278    AC A0A2I0P8G2.1
#=GS MCRA_METJA/5-271          AC Q58256.2
#=GS E1RDX4_METP4/8-278        AC E1RDX4.1
#=GS A0A0A7LF46_9EURY/7-271    AC A0A0A7LF46.1
#=GS A0A150IVI7_9EURY/7-272    AC A0A150IVI7.1
#=GS Q0W339_METAR/7-274        AC Q0W339.1
#=GS E1RJD5_METP4/8-278        AC E1RJD5.1
#=GS A0A166CWD2_9EURY/3-268    AC A0A166CWD2.1
#=GS MCRX_METJA/5-271          AC Q60391.1
#=GS A2SSD1_METLZ/8-278        AC A2SSD1.1
#=GS A0A0U3E6Z6_9EURY/3-268    AC A0A0U3E6Z6.1
#=GS A0A0P9E1V1_9ARCH/40-304   AC A0A0P9E1V1.1
#=GS M9SBG6_METAX/7-271        AC M9SBG6.1
#=GS A5ULZ2_METS3/3-268        AC A5ULZ2.1
#=GS A2STR9_METLZ/8-278        AC A2STR9.1
#=GS D3E050_METRM/3-268        AC D3E050.1
#=GS A0A0P6VHH7_9EURY/14-282   AC A0A0P6VHH7.1
#=GS A3CT46_METMJ/8-278        AC A3CT46.1
#=GS A0A1F2P3F1_9EURY/6-277    AC A0A1F2P3F1.1
#=GS A0A0E3NU58_9EURY/14-282   AC A0A0E3NU58.1
#=GS A0A0Q4BCJ2_9EURY/1-261    AC A0A0Q4BCJ2.1
#=GS A0A0E3SA85_9EURY/14-282   AC A0A0E3SA85.1
#=GS A0A0U2L5Y3_9EURY/5-271    AC A0A0U2L5Y3.1
#=GS A0A1F2P729_9EURY/2-269    AC A0A1F2P729.1
#=GS F0TCV5_METLA/5-270        AC F0TCV5.1
#=GS Q2FSN0_METHJ/8-277        AC Q2FSN0.1
#=GS D5EAD6_METMS/14-284       AC D5EAD6.1
#=GS A0A2I0PSL8_9EURY/10-278   AC A0A2I0PSL8.1
#=GS M4YK22_THEXX/5-269        AC M4YK22.1
#=GS A0A219ALM7_9EURY/3-268    AC A0A219ALM7.1
#=GS B8GE93_METPE/8-277        AC B8GE93.1
#=GS F6D2D3_METPW/3-268        AC F6D2D3.1
#=GS MCRA_METKA/6-271          AC Q49605.2
#=GS MCRA_METKA/6-271          DR PDB; 1E6V A; 8-271;
#=GS MCRA_METKA/6-271          DR PDB; 1E6V D; 8-271;
#=GS A0A166C196_9EURY/3-268    AC A0A166C196.1
#=GS A5ULM9_METS3/5-271        AC A5ULM9.1
#=GS U6EF81_9EURY/5-270        AC U6EF81.1
#=GS A0A1F2P3I8_9EURY/2-269    AC A0A1F2P3I8.1
#=GS MCRA_METTH/3-268          AC O27232.3
#=GS U6EEP1_9EURY/3-268        AC U6EEP1.1
#=GS A0A120K0D9_9EURY/3-268    AC A0A120K0D9.1
#=GS A0A2I0P7B3_9EURY/8-278    AC A0A2I0P7B3.1
#=GS A7I5T9_METB6/10-278       AC A7I5T9.1
#=GS R9TAZ9_METII/3-268        AC R9TAZ9.1
#=GS K4MC35_9EURY/14-283       AC K4MC35.1
#=GS Q6LWZ5_METMP/5-272        AC Q6LWZ5.1
#=GS A6UWH2_META3/5-271        AC A6UWH2.1
#=GS F4BXY1_METSG/7-276        AC F4BXY1.1
#=GS A0A062V7W6_9EURY/13-283   AC A0A062V7W6.1
#=GS A0A1D2WBA8_9EURY/3-268    AC A0A1D2WBA8.1
#=GS F0T8R3_METLA/3-268        AC F0T8R3.1
#=GS A0A166A6T9_9EURY/3-268    AC A0A166A6T9.1
#=GS Q2NHZ8_METST/5-271        AC Q2NHZ8.1
#=GS A0A1D2WLQ3_9EURY/5-271    AC A0A1D2WLQ3.1
#=GS A0A0P8CBK4_9EURY/10-279   AC A0A0P8CBK4.1
#=GS A0A0W7TIP2_9EURY/7-271    AC A0A0W7TIP2.1
#=GS L0HD22_METFS/10-280       AC L0HD22.1
#=GS D7DUH5_METV3/5-272        AC D7DUH5.1
#=GS A0A124G584_9EURY/8-278    AC A0A124G584.1
#=GS D1YVW6_METPS/7-275        AC D1YVW6.1
#=GS L0HIJ7_METFS/11-279       AC L0HIJ7.1
#=GS J0RY59_9EURY/8-278        AC J0RY59.1
#=GS G7WN24_METH6/7-276        AC G7WN24.1
#=GS F7XL13_METZD/14-283       AC F7XL13.1
#=GS A0A1V6N4K9_9EURY/3-268    AC A0A1V6N4K9.1
#=GS J0SAE9_9EURY/8-278        AC J0SAE9.1
#=GS A0A0E3SNQ2_METBA/14-282   AC A0A0E3SNQ2.1
#=GS A0A0F8E165_9EURY/14-282   AC A0A0F8E165.1
#=GS A0A1F2P6A2_9EURY/2-269    AC A0A1F2P6A2.1
#=GS A0A1F2PC64_9EURY/2-269    AC A0A1F2PC64.1
#=GS F6BE97_METIK/5-271        AC F6BE97.1
#=GS A0A1D2X2N6_9EURY/5-271    AC A0A1D2X2N6.1
#=GS A0A1I4S1G7_9EURY/14-283   AC A0A1I4S1G7.1
#=GS Q8PXH8_METMA/14-282       AC Q8PXH8.1
#=GS A0A0E3S2W5_9EURY/14-282   AC A0A0E3S2W5.1
#=GS D7E8X7_METEZ/15-284       AC D7E8X7.1
#=GS A0A1D3L4K2_9EURY/3-268    AC A0A1D3L4K2.1
#=GS F6BBJ2_METIK/5-270        AC F6BBJ2.1
#=GS A0A150J824_9EURY/7-272    AC A0A150J824.1
#=GS I7LMP5_METBM/8-278        AC I7LMP5.1
#=GS A0A139CTB8_9EURY/14-283   AC A0A139CTB8.1
#=GS A0A0E3NNS2_9EURY/14-282   AC A0A0E3NNS2.1
#=GS A0A1E7GGH8_9EURY/14-282   AC A0A1E7GGH8.1
#=GS A0A1F2PDF7_9EURY/167-444  AC A0A1F2PDF7.1
#=GS A0A1Y3GED3_9EURY/6-271    AC A0A1Y3GED3.1
A0A166B5P3_9EURY/5-271               ..............n-KKFLSALT.E.KFKGE.DQKSDHTSFYCFDGWKQSPRKREFNDVAEK.L.AKER..NMPFYNPDI---....GVPLGQRQLMAYKISGT.DSY........VEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGLAQDCYAKIFTGNDDLADELDKRVLIDINKEFPEDQAEMLKSYIGNKTYQVSRVPTLVVRSCDGGTVSRWSAMQIGMSFINAYKLCAGEAAIADFSYAAKHADVIGMASFLP...............
A0A1F2P9A1_9EURY/5-276               ..............k-KTHIKLLE.E.TFKVS.PTDIVDKKLYQHGGTRQSKRKTEYIEYANR.I.AKER..GIPAYDPDHIALelevGVPLGQRYLEPVKISGT.DVM........CEYEDLHIMNNVAIEQMVDDIFRTAIVCIDLPHKVLVDRYGFEVTPESINTYLETINHTMVGGAVTQEHMCEMHPGPCADGYVKIFTGNDEVASSLDSRFVIDINKEFTPEKAAKLKEGVGDSLWQVSRVPTHALRTMDGAIIHRWNAMGQTMAFIASYHLCAGEAAISDFAYAAKHAQYIWMGT---p..............
Q8THH1_METAC/14-282                  ..............e-VKFTQEYG.S.NKQAGgDITGKTEKF-LRLGPEQDARKQEMIKAGKE.I.AEKR..GIAFYNP-MMHM....GAPLGQRAITPYTISGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLETLNHAMPGAAVVQEMMVETHPALVDDCYVKIFTGDDELADEIDKQYVINVNKMFSEEQAAQIKASIGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
MCRA_METBF/14-282                    ..............e-VKFAQEFG.S.NKQTGgDITDKTAKF-LRLGPEQDPRKVEMIKAGKE.I.AEKR..GIAFYNP-MMHS....GAPLGQRAITPYTISGT.DIV........CEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQEMMVETHPALVDDCYVKVFTGDDALADEIDKQFLIDINKEFSEEQAAQIKASIGKTSWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
#=GR MCRA_METBF/14-282         SS    ..............H-HHHTS--T.T.-------TT-SEE-------GGGSHHHHHHHHHHHH.H.HHHH..TS----G-GGSS....SS-S-SS----EEBTTS.--E........E-GGGGSGGG-HHHHHHHHHHHTEEEEESHHHHHHHHHHH-----HHHHHHHHHHHHHHTTT--SS-SS-----GGGSTT-EEEEEES-HHHHTTS-GGGB--HHHHS-HHHHHHHHHHH-S-EEEEEE--HHHHHHS-TTHHHHHHHHHHHHHHHHHTT--TT-HHHHHHHHHHHTTTEE-SS--B-...............
A0A101IGB4_9EURY/36-214              .............pt---------.-.-----.------------------------------.-.----..------------....-----------------.---........-----------HAMQQMWDDIRRTIVVGLDMAHEVLEKRLGKEVTPETINNYLEILNHAMPGAAVVQEHMVETHPGLVDDCNVRMFTGDDDLADEIDDQYIIDINKLFPAEQAEEIKAAMGKTSWQAIHIPTIVSRTCDGGTTSRWSAMQLSMTFIDAYNMCAGEAAVADLAFAAKHAAVIQMADMLP...............
Q8TVA5_METKA/8-60                    ..............e-ALFIKALK.E.KFE-E.DPEEKHTKFYVYGGYRQSPRKE-FA-----.-.----..------------....-----------------.---........--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------kgalrefepagerdl
Q12TF8_METBU/14-283                  ..............e-IKFTKAHG.D.NKMEGgEITDKKVTYY-RLGVDQNPRKVEMRKAGQE.I.ADKR..GLVGYNP-MMHC...gGIPLGQRALTPSFISGT.DIM........VESDDLHYVNNAAMQQMWDDIRRTTIVGMDMAHETLEKRLGIEVTPETINHYLEVLNHALPGGAVVQEHMVETHPALVDDCYCKIFTGDDELADEIDDQFLININKQFPEEQAEALKAAIGKTTWQAAHIPTIVSRTTDGAQTSRWMAMQVGMSFIAAYNMCAGEAAVADLSYAAKHAGVISMGDMLP...............
A0A059TIR1_9EURY/6-270               ...............QKLFLEACK.K.KFK-E.EPTQMDTKYYCYGGWKQSKRKVELQATAAE.I.AKKR..GFPMMNEDI---....GVPLGQRSWMPYQLSHT.DIF........VEPDDLHCINNPAIQQAWDDIRRTVLVGLDFPHQTIEKRLGKEVTPETISNYLEVVNHTMPGGAVVQEHMAECNPALVADSYVKVFSGNDDLIDEIDPRFVIDINKNFPKEQAAQLKKAIGNTFMQAVRVPTMVGRLMDGGTVSRHAAMQISMAFISAYKLAAGEAAIADFAYSAKHQS-ITMGSMMP...............
A0A150JIY1_9EURY/7-272               ..............k-HNFMQAMK.K.KFE-E.APDKRQTKFYVYGGYKQNKRKVEFHDAGQQ.I.AKER..GIPGYNPSV---....GMPQGQRVLMPYQLSHT.DII........ANMDDLHFVNNAAMQQAWDDMRRTILVGLDSPHNILEKRLGKEVTPETINHYLEVVNHSMPGAAVIQEHMVETDPRLVKDSYVKVYSGNDELIDEIDSRFVIDINKEFPADQAAQLKKAIGKSMWQVVRIPTVVGRVCDGGTVSRWSAMQIGMAFIGAYNLCAGEAATADFAYAAKHGSVIQMSDMMP...............
H1YXH9_9EURY/8-278                   ...............QKLFLDALK.Q.KFQGE.DVESVKTTFYNFDGVRQSPRKREFMEATKA.V.EAKR..GMAMYDPEHCHL...gGLPMGQRQLMTYEVSGT.GTF........VEGDDLHFVNNAAMQQFWDNIRRTVIVGMDLAHATLQKRLGKEVTPETINEYLHILNHAMPGAAVVQEHMVETHPGLVDDCYVKVFTGDDEMADDIEPQFLINVEKLFPAEQAEVLKAEVGKSMYQAIHIPTIVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVVQMASHLP...............
A0A1Y3GE24_9EURY/5-270               ...............EKRFIKALK.N.KFE-E.EPTDTKTHFYDLGGYKQSERKKEFQERAAQ.I.AKER..GTPSLNEDI---....GVPLGQRVLMPYQLSHT.DTM........VEPDDLHIINNAAMQQAWDDIQRTVIVGLDTAHQVMEKRLGVEVTPETINEYLEVFNHTQPGGAVVQEHMAECNPGVTGDAYVKVFTGNDELADEIDDNLLIDINENFPEDQAEQLKEAIGDSLWQAIRAPTIVTRVMDGATIRRWAAMQSSMAFISSYSLCAGEAAIADFAYASKHSKVINMASAMP...............
L0L0H0_METHD/13-282                  .............ei--KFTKEHG.AnKMEGG.KITDMVGKYY-RLGVDQNPRKVEMKKAGQE.L.AKKR..GLVGYNP-MMHC...gGIPLGQRALTPSFISGT.DMM........VEVDDLHYVNNAAMQQMWDDIRRTCIVGIDLAHETLEKRLGIEVTPETINFYLETLNHALPGGAVVQEHMVETHPALVDDCYCKIFTGDDELADEIDKQFLIDINKEFPEEQAAQIKAAIGKTTWQAAHIPTVVSRVTDGAQTTRWMAMQVGMSFISAYSMCAGEAAVADLSYAAKHAGVISMGEMLP...............
W9DZJ0_METTI/14-283                  ............eik---YTKEHGtN.KMEGG.KITDKTVEYY-RLGVDQNPRKLEMKKAGQE.L.AKKR..GLVGYNP-MMHC...gGIPLGQRALTPSFLSGT.DDM........VEIDDLHYVNNAAMQQMWDDIRRTVIVGLDMAHETLEKRLGIEVTPETINHYLETLNHALPGGAVVQEHMVETHPALVDDCYVKMFTGDDELADEIDSQFLIDINKAFPEEQAEQLKAAIGKNSFQAAHIPTIVSRTTDGGQTSRWMAMQVGMSFISAYSMCAGEAAVADLSYAAKHAGVVQMGEMLP...............
A0A0P9HYI1_9ARCH/41-306              ...........rrai----YSRLE.K.QFGAD.PLSLVDSEMYKRGGYRQSKRKQEFVKSGRQ.I.AIER..GIPAYNRAV---....GIPLGQRILEPYVITGT.DIT........VEQDDTHHVNNPAIQQMVDDIKRTTIVNIDIAHRMLQVRAGKEVTPETINLYLETLNHTMCGGAVAQEHMSEINPLLVKDAYAKVITGSDEIKDALDRRYVIDIDRLFHPTRAEQLKKALGNSIWVVLRTPTIAIRMADGDEAHRWAAMQNTMAFIGSYGL-SGEHVVSDLAYSFKHARVVNMGNKM-w..............
A0A1D2W9L6_9EURY/5-271               ...............KKLFAKALK.G.KFD-E.DPNENHTNFYCFGGWEQSARKKEFNAEAEK.L.MEER.gGVPFYNPDI---....GVPLGQRKLMAYKVSGT.DSY........VEGDDLHFLNNAAIQQLLDDIKRTVIVGMDTGHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVNPGLVGDCYAKIFTGDDNLADELDKRVLIDINKEFPEEQAEMLKKYVGKKTYQVSRVPTAVVRSCDGGTVSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVIGMGAILP...............
R9SLW2_9EURY/3-268                   ...............DKKFYEALN.K.KFK-E.SPEDKTTTFYNLGGWKQSERKTQFYEAGKE.I.AEER..GIPMYNPDI---....GSPLGQRTLMPYQLSTT.DTF........VEGDDLHFINNAAIQQLWDDIRRTVLVGLNTAHNVLQRRLGMEVTPETITNYLETVNHAMPGAAVVQEHMVETNPYLVSDSYVKIFTGDDELADEIDQCYVLDINKEFPDDQAAQLKAEVGDKIWQVVRVPSLVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAFATKHAEVIQMGAPLP...............
A0A1D2WJY0_9EURY/3-268               ...............DKKFLNAMK.Q.KFS-E.DPTEKSTQFYNMGGWTQSERKTAFVNEGKE.I.AEKR..GIPMYNPDI---....GTPLGQRALMSYQLSTT.DTF........VEGDDLHFINNAAIQQAWDDIRRTVIVGLNTAHNVLEKRLGIEVTPETITNYLETVNHAMPGAAVVQEHMVETDPLLVADSYVKVFTGDDELADEIDSAFVLDINKEFNEEQAEALKAEVGSAVWQAVRIPSIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVVQMGTYLP...............
E3GZ51_METFV/6-271                   ...............KKLFVDALR.K.KFK-E.EPKERKTTFYTLGGWKQSERKKEFVEYGKK.V.AKER..GIPAYNPDI---....GTPLGQRVLMPYQVSTT.DTF........VEGDDLHFVNNAAMQQFWDDIRRTVIVGLNHAHRILERRLGKEVTPETINHYLETVNHAMPGAAVVQEHMVETHPGLTADSYVKVFTGNDELADEIESCYLIDINKQFPEHQAEQLKKAIGDSIWQAVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATADFAYAAKHAEVIHLGTFLP...............
A0A1F2P8K6_9EURY/59-323              ..............q-REMYKALH.T.LFEGE.PMDTVDKQSYRHGGVQQSRSKRMWVEWGKK.I.AIER..GIPQYNREM---....GIPLGQRYYEPVLVSNT.DYI........VDYDDFSVYNNCAIQQMMDDMRKTVIMGLDVPHRVIQLRLGKEISPESMNLYMETIQHVLAGGAVVQEHMAETHPGLVTDAYAKIITGNPDLRDQFDRRWVLNIDKEFHPTRAEPLNEMIGNRLFNTIRTHTLRVRMTNGAAVIRSAAIAVTMSFVAAYKL-TGESVLSDISFATRHAQAIHMG----lat............
A0A2A2HEG1_9EURY/8-275               ...............KKLFLKALQ.E.KFD-E.DPEDEKTKFYCYGGWEQSPRKREFDEEAKKaI.AEER.gGLPFYNPDI---....GVPLGQRKLMAYQVSGT.DTY........VEGDDLHFCNNSAIQQLVDDIKRTIIVGMDTAHGVLEQRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGLVADSYAKVFSGDDELIDQIDSRFVIDINKQFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVISMGSAMP...............
A0A166CHN2_9EURY/3-268               ...............DKKFIDALN.K.KFK-E.DPTEKSTTFYNLGGWTQSERKTEFANAGKE.I.AEKR..GIPQYNPDV---....GSPLGQRALMPYQVSTT.DTY........VEGDDFHFVNNAAIQQMWDDIRRTVIVGLNTAHNVIEKRLGMEVTPETITHYLETVNHAMPGAAVVQEHMVETNPLLVADSYVKIFTGDDELADEIDKAYVLDINKEFNEEQAAALKAEVGDNIWQVVRIPSIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVIHMGTYLP...............
A3CSG1_METMJ/8-278                   ...............QKLFLKALK.E.KFQGQ.DVESETAEFYNFNGVRQSPRKMEFMKASRA.V.EMDR..GISMYDPERCHL...gGIPMGQRQLMTYEVSGT.GVF........VEGDDLHFVNNSAMQQMWDDIRRTVIVGMDLAHQTLQKRLGKEVTPETINEYLHILNHAMPGGAVVQEHMVETHPGLVDDCYVKVFTGDQELADDIEPQFLLNIEKLFPAKQAEELKAEVGKSMYQAIHIPTAVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSYAAKHAGVVQMGSILP...............
A0B6N6_METTP/7-276                   ...............KKLFVRALT.K.KFGKDfDLSSQKTEY-KRLGPEQSARKREFMEYSKK.L.EGKR..GISFYNP-YLHC...gGVPLGQRQLVPYKLSNT.EYI........VEGDDLHFVNNPAMQQMWDDIRRTVVVGLDMAHEVLEKRLGKEVTPETINNYLEILNHAMPGAAVVQEHMVETHPGLVEDCNVRVFTGDDDLADEIDPQYLIDINKLFPADQAEQLKAAIGKTTWQAIHIPTIVVRSCDGGTTSRWSAMQLSMTFIDAYNMCAGEAAVADLAYAAKHAAVLQMSDMLP...............
D5VQU8_METIM/5-271                   ..............k-RLFLKALK.E.KFE-E.DPREKYTKFYIFGGWRQSARKREFVEAAQK.L.IEKR.gGIPFYNPDI---....GVPLGQRKLMPYKVSNT.DAI........VEGDDLHFMNNAAIQQMWDDIRRTVIVGMDTAHAVLEKRLGVEATPETINEYMEVINHALPGGAVVQEHMVEVHPALVWDCYAKIFTGDDELADEIDKRFLIDINKLFPEEQAEQIKKAIGKRTYQVSRVPTLVGRVCDGGTIARWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMATFLP...............
A0A150J3N1_9EURY/7-272               ..............k-HNFMQAMK.K.KFE-E.APDKRQTKYYVYGGFKQNKRKVEFYEAGQQ.I.AKER..GIPGYNPSV---....GMPQGQRVLMPYQLSHT.DII........ANMDDLHFVNNAAMQQAWDDMRRTILVGLDSPHNILEKRLGKEVTPETINHYLEVVNHSMPGAAVIQEHMVETDPRLVKDSYVKVYSGNDELIDEIDSRFVIDINKEFPADQAAQLKKAIGKSMWQVVRIPTVVGRVCDGGTVSRWSAMQIGMAFIGAYNLCAGEAATGDFAYAAKHGSVIQMSDMMP...............
MCRX_METFV/6-272                     ...............KKLFLEALE.K.KFKGE.SPEEKKTTFYCFGGWKQSERKREFVEYAKK.L.AKKR..GIPFYNPDI---....GVPLGQRKLMAYRISGT.DAY........VEGDDLHFVNNAAIQQMVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGLVDDCYAKIFTGNDELADELDKRVLIDINKEFPEEQAEMLKKYIGNRTYQVNRVPTIVVRCCDGGTVSRWSAMQIGMSFISAYKLCAGEAAIADFSFAAKHADVIEMGTILP...............
I7KDB2_METBM/8-278                   ...............QKLFLKALK.E.KFQGQ.DVQSDTAEYYKYNGVRQSPRKMEFMKASRA.I.EMDR..GISMYDPERAHL...gGIPMGQRQLMTYEVSGT.GVF........VEGDDLHFVNNAAMQQFWDDIRRTVIVNMDLAHQTLQKRLGKEVTPETINEYLHILNHAMPGAAVVQEHMVETHPGLVDDCYVKVFTGDQELADDLEPQFVLDVEKLFPAKQAEALSAAVGKSLWQAIHIPTAVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVIQMASLLP...............
A0A1Q6DVQ2_9EURY/3-269               ..............e-EKFIESLK.N.KFEED.PTSKNQKSLYQLGGYKQSKRKKEFQEAGQQ.I.AKER..GTSSFNEDI---....GVPLGQRVLMPYQLSHT.DMT........VEPDDLHVLNNAAMQQAWDDIQRTVIVGLDMSHKVLEKRLGKDVTPETINQYLETYNHTQPGGAVVQEHMAECNPGVTGDAYVKVFTGDDELKDEVDDQFLLDIDEKFPEDQAEQLKDAIGETTWQILRVPTIVVRTMDGATVRRWAAMQSCMAFISAYNLCAGEAPVSDFVFAAKHQSVVNMGSAMP...............
MCRX_METTH/4-271                     ...............KKLFLTALK.K.KFEVE.DPDEKYTNFYCFGGWEQSARKKEFTEYAKK.A.AEKR.gGIPFYNPDI---....GVPLGQRKLMAYRVSGT.DAY........VEGDDLHFVNNAAIQQMVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMEAINHALPGGAVVQEHMVEVHPGLVEDCYAKIFTGDDNLADELDKRILIDINKEFPEEQAEQLKSYIGNRTYQVNRVPTIVVRTCDGGTVSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVIEMGTIMP...............
A0A2I0P8G2_9EURY/8-278               ...............QKLFLKALK.E.KFQGQ.DVESETAEFYKFNGVRQSPRKMEFMKASRA.V.EMDR..GVSMYDPERCHL...gGIPMGQRQLMTYEVSGT.GVF........VEGDDLHFVNNAAMQQMWDDIRRTVIVGMDLAHQTLQKRLGKEVTPETINEYLHILNHAMPGGAVVQEHMVETHPGLVDDCYVKVFTGDQELADDIEPQFLLDIEKLFTAKQAEELKAEVGKSMYQAIHIPTAVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSYAAKHAGVIQMGSHLP...............
MCRA_METJA/5-271                     ..............k-RLFLKALK.E.KFE-E.DPREKYTKFYVFGGWRQSARKREFVEAAQK.L.IEKR.gGIPFYNPDI---....GVPLGQRKLMPYKVSNT.DAI........VEGDDLHFMNNAAMQQFWDDIRRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPALVWDCYAKIFTGDDELADEIDKRFLIDINKLFPEEQAEQIKKAIGKRTYQVSRVPTLVGRVCDGGTIARWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMASFLP...............
E1RDX4_METP4/8-278                   ...............QKLFLNALK.E.KFQGE.DPESVKTTFYNFDGVRQSPRKREFMAEAKK.V.EMKR..GISMYDPEHCHL...gGLPMGQRQLMTYQVSQT.DVF........VEGDDLHFVNNAAMQQMWDDIRRTVIVGMDLAHATLQKRLGKEVTPETINEYLHILNHAMPGGAVVQEHMVETHPGIVDDCYVKVFTGDDEMADDIEPQFLLNVDKLFNAEQAEVLKKQVGKSMYQAIHIPTIVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVIQMATHLP...............
A0A0A7LF46_9EURY/7-271               ...............DKLFMDAVK.K.KFK-E.DPTDMETKYYCYGGWRQSKSKVEFQKAAQA.I.AKKR..GFPMMNEDI---....GVPLGQRAWMPYQLSHT.DIY........VEVDDLHCINNPAIQQAWDDIRRTILVGLNSPHETIEKRLGKEVTPETINNYLEAVNHTMPGGAIVQEHMAECNPALVSDSYVKVYSGDDELIDEIDKRFVIDINKLFPKAQADQLKKAIGKNLMQAVRVPTMVGRLMDGATVSRHAAMQISMAFISSYKLAAGEAAIADFAYSAKHLS-INMGTMMP...............
A0A150IVI7_9EURY/7-272               ..............k-HNFMQAMK.K.KFE-E.APDKKQTKYYVYGGYKQNKRKVEFFEAGQQ.I.AKER..GIPGYNPSV---....GMPQGQRVLMPYQLSHT.DII........ANMDDLHFVNNAAMQQAWDDMRRTILVGLDSPHNILEKRLGKEVTPETINHYLEVVNHSMPGAAVIQEHMVETDPRLVKDSYVKVYSGNDELIDEIDSRFVIDINKEFPADQAAQLKKAIGKSMWQVVRIPTVVGRVCDGGTVSRWSAMQIGMAFIGAYNLCAGEAATGDFAYAAKHGSVIQMSDMMP...............
Q0W339_METAR/7-274                   ...............QKRFIKAMK.K.KFA-E.EPTAQVTKF-KYEGYTQSKRKVEFKKTGDA.I.AKKR..GISMYNP-MVHM...gGIPLGQRQLMNYVVSGT.DIA........VEGDDLHFVNNAAMQQFWDEIRRTVIVGLDTAHATLEKRLGKTVTPETISNYLAVLNHAMPGAAVVQEHMVETHPGLTDDCFVKVFTGDDELADSIDKQYVLDINKAFPKEQAAQLKKAIGKQLFQAVHIPTIVVRTCDGGTTSRWSAMQIGMSFIDAYKMCAGEAAVADLAFAAKHASVVEMGNLLP...............
E1RJD5_METP4/8-278                   ...............QKLFLNALK.E.KFQGQ.DIESERTTFYNFDGVRQSPRKREFMAETVE.I.EKKR..GISMYDPERCHL...gGIPMGQRQLMTYEVSGT.NTF........VEGDDLHFVNNAAMQQMWDEIRRTVIVGMDMAHATLQKRLGKEVTPETINEYLHILNHAMPGGAVVQEHMVETHPALTDDCFVKVFTGDDELADDIDPQYLINIDKLFPENQAAELKEEVGKSIFQAIHIPTIVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVIQMGTILP...............
A0A166CWD2_9EURY/3-268               ..............n-KKFIEALN.K.KFK-E.SPEEKTTTFYNLGGWKQSERKSEFAKEGKE.I.ATKR..GIPQYNPDV---....GSPLGQRALMPYQVSTT.ETF........VEGDDFHFVNNAAIQQMWDDIRRTVIVGLNTAHTVLEKRLGIEVTPETITEYLETVNHAMPGAAVVQEHMVETNPALVADSYVKIFTGDDEVADEIDSAFVLDINKEFSKEQAEALKAEVGDKIWQVVRIPSIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVIHMGTYLP...............
MCRX_METJA/5-271                     ...............KKLFLKALK.E.KFE-E.DPKEKYTKFYIFGGWRQSARKREFVEFAQK.L.IEKR.gGIPFYNPDI---....GVPLGQRKLMTYKISGT.DAF........VEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGLVWDCYAKIFTGNDELADEIDKRFLIDINKEFPEEQAEQIKKYIGNRTYQVSRVPTIVVRCCDGGTVSRWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMGMILP...............
A2SSD1_METLZ/8-278                   ...............QKLFLDALK.Q.KFPKQ.DVASVQTEFYKFNGVQQSPRKREFMAENKK.I.EAAR..GISMYDPEHCHL...gGIPMGQRQLMTYEVSGT.GTF........VEGDDLHFVNNAAMQQMWDDIRRTVIVSMDMAHQTLQKRLGKEVTPETINEYLHVVNHAMPGGAVVQEHMVETHPGLTDDCYVRVFTGDQELADNLEPQFVIDVEKLFPKKQAEALQAAVGKSLWQCVHMPTIVGRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVINMAHHLP...............
A0A0U3E6Z6_9EURY/3-268               ...............DKKFLDAMK.Q.KFS-E.DPTEKTTQFYNMGGWTQSERKTAFVNEGKE.I.AEKR..GIPMYNPDI---....GTPLGQRALMSYQLSTT.DTF........VEGDDLHFINNAAIQQAWDDIRRTVIVGLNTAHNVLEKRLGIEVTPETITNYLETVNHAMPGAAVVQEHMVETDPLVVQDSYVKVFTGDDELADEIDSAFVLDINKEFPEEQAEALKAEVGGAVWQAVRIPSIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVVHMGTYLP...............
A0A0P9E1V1_9ARCH/40-304              ...........krpm----YAAME.R.TFGSD.PFQRIDPKMYKRGGFRQSKRKQEFVRLGRQ.V.AIER..GLPAYNRAM---....GIPLGQRQLEPFSVGKT.GIL........AEQDDLHHVNNPAIQQMVDDIKRTTIVNLDIAHRMLQVRAGKEVTPETINLYLETLNHTMCGGAVAQEHMSEINPLLVKDAYAKVITGSDEIKDALDRRFVIDLDKQFHPTRAKKLKEAIGNTIWVVLRAPTIAIRMADGEEAGRWSAMQNTMAFIGSYGL-SGEQVVSDLAYSFKHARVIRMGN---kf.............
M9SBG6_METAX/7-271                   ...............EKLFLEACK.K.KFK-E.DPTSMETKYYCYGGWKQSKSKVEFQKEAME.I.AKKR..GFPMMNEDI---....GVPLGQRSWMPYQLSHT.DIF........VEPDDLHCINNPAIQQAWDDIRRTVLVGLDSPHQTIERRLGKEVTPETINAYLETVNHTMPGGAVVQEHMAECNPALVYDSYVKVFSGDDELIDELDPRFVIDINKNFPKDQAEKLKKAIGKTVMQAVRVPTMVGRVMDGATVSRHAAMQISMAFISSYKLAAGEAAIADFAYSAKHMS-INMGSMMP...............
A5ULZ2_METS3/3-268                   ...............DKKFLDAMK.N.KFS-E.GPTDKRTTFYNMGGWKQSERKSAFVKEGKE.I.AEKR..GIPMYNPDI---....GTPLGQRALMSYQLSTT.DTY........VEGDDLHFINNAAIQQAWDDIRRTVIVGLNTAHNVLEKRLGIEVTPETITEYLETVNHAMPGAAVVQEHMVETDPLVVQDSYVKVFTGDDELADEIDSAFVLDINKEFNEEQAAALKEEVGGSVWQAVRIPAIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVIHMGTYLP...............
A2STR9_METLZ/8-278                   ...............QKLFLDALK.Q.KFPKQ.DVASTTAEFYKFNGLEQSPRKREFMAENKK.I.EAAR..GISMYDPNRCHL...gGIPMGQRQLMTYELSGT.GTF........VEGDDLHFVNNAAMQQMWDDIRRTVIVSMDMAHQTLQKRLGKEVTPETINEYLHVVNHAMPGGAVVQEHMVETHPGLTDDCYVRVFTGDQELADNLEPQFVIDVEKLFPKKQAEALQAAVGKSLWQCVHMPTIVGRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVINMAHHLP...............
D3E050_METRM/3-268                   ...............DKKFLDAMT.K.KFK-E.APEEKTTTFYNMGGWTQSERKTEFVNEGKA.I.AEAR..GIPMYNPDI---....GNPLGQRALMSYQLSGT.DTF........VEGDDLHFINNAAMQQAWDDIRKTVIVGLNTAHNVLEKRLGMEVTPETITNYLEVVNHAMPGAAAVQEHMVETNPLLVDDSYVKVFTGDDDLAAEIDPAFVLDINKEFPEEQAEALKAEVGGAIWQIVRVPSVVGRVCDGGTTSRWSAMQIGMSMISAYGQCAGEGATGDFAYASKHAEVIGMGTYLP...............
A0A0P6VHH7_9EURY/14-282              ..............e-VKFAQEFG.S.NKQTGgDITSNTTKF-LRLGPEQDDRKVEMIKAGKE.I.AEKR..GLAFYNP-MMHS....GAPLGQRAITPYTISGT.DMV........CEPDDLHFVNNAAMQQFWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQEMMVETHPALVDDCYVKVFTGDDSLADEIDKQFLIDINKEFPEEQAAQIKASIGKTSWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
A3CT46_METMJ/8-278                   ...............QKLFLKSLK.E.KFQGQ.DVESETTEFYKFNGYHQSPRKEEFVKASRA.V.EMDR..GISMYDPVRCHL...gGIPLGQRQLMTYEVSGT.GVF........VEGDDLHFVNNAAMQQMWDDIRRTVIVNMDLAHQTLQKRLGKEVTPETINEYLHVLNHAMPGAAVVQEHMVETHPGLVDDCYVKVFTGDQELADDLEPQFVLDVEKLFPAKQAEALSAAVGKSLWQAIHIPTTVSRTCDGGTTSRWSAMQIGMSFIGAYRMCAGEAAVADLSYAAKHAGVIQMASHLP...............
A0A1F2P3F1_9EURY/6-277               ............tke---HIKWLE.E.TYKVE.ATDIIDKKLYQHGGTRQSKRKTEYIEYANK.I.AKER..GIPSYDPDHIALeleiGVPLGQRYLEPVKISGT.DVF........CEYEDLHMLNNAAIQQMIDDIFRTAIVCLDLPHRVLIDRYGFEVTPESINRYLETINHTMVGGAVAQEHMCELHPGLCPDGYVKVFTGDDDVANSLDKRFVIDINREFPEEKAAKLKEGVKRSLWQVSRIPTHALRSMDGGMVHRWNAMGQTMAFISSYHLCAGEAAISDFAYAAKHAQYIWMGT---p..............
A0A0E3NU58_9EURY/14-282              .............ev--KFAQDYG.T.NQLGGsDIEAKTSKF-LRLGPEQSPRKVEMIAAGKE.I.AEKR..GIVGYNPNM-HM....GAPLGQRAITPYTLSGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLETLNHAMPGAAVVQEMMIETHPALVDDCYVKIFTGDDALADEIDSQFVININKMFPEEQAEQIKASIGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFSAKHASLVSMGEMLP...............
A0A0Q4BCJ2_9EURY/1-261               ..............m-----AAVK.K.KFK-E.DPTDEYTSYYKFGGWRQSKRKVEFVEAANK.I.AKER..GIPMMNQDI---....GVPLGQRSWMPYQLSHT.DIY........VEPDDLHCINNPAIQQAWDDIRRTILVGLDAPHQTIEKRLGKEVTPETINEYLEAVNHTMPGGAVVQEHMAEINPALAYDSYVKVYSGNDELIDELDKRFVIDINKLFSKDHAAQLKKAIGSTLMQAVRVPSIVGRVMDGATTSRHAAMQISMAFITSYRLAAGEAAIADFAYSAKHQS-LPMGTMMP...............
A0A0E3SA85_9EURY/14-282              ..............e-VKFTQEYG.S.NQQSGgDITGKTEKF-LRLGPEQDARKVEMIKAGKE.I.AEKR..GIAFYNP-MMHM....GAPLGQRAITPYTISGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQEMMVETHPALVDDCYVKIFTGDDELADEVDKQFVININKMFNEEQAAQIKASIGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
A0A0U2L5Y3_9EURY/5-271               ...............DKKFLNALN.Q.KFKGE.DQESDHTSFYCFDGWKQSERKREFNDAAEK.L.AKER..NMPFYNPDI---....GVPLGQRQLMAYKISGT.EDY........VEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPSLVDDCYAKIFTGNDDLADELDKRVLIDINKEFPEDQAEMLKKYVGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFINAYKLCAGEAAIADFSYAAKHADVIGMGAFLP...............
A0A1F2P729_9EURY/2-269               .............de--KILDDFK.R.IFKEE.DPTKRETQFYNFGGRTQSKAKREFIESAKR.I.AETR..GIPGYQGDREDF....GVPLGSRYLEPYHIAGT.DTF........CEMDDIHQINNAAIQQMGDDIKRTAINGLDLPHRVLQQKVGIAVTPETINRYLEAVNHSIVGGALAQEHMAEINPNMSKDGYAKIITGDDELVDRIDSRFVIDINKEYPKEMAEKLKSKIGNHLYQVARIPTIGVRIADGSVVHRWNGNQSALAFVSTYNLGGG-SILAEFSLTVKHMAYMLIG----tpt............
F0TCV5_METLA/5-270                   ...............KKLFLKALK.N.KFN-E.DPNEHYTDYYCYGGWEQSPRKKEFNEFSKK.L.EEER..GLPGYNPDI---....GVPLGQRKLMSYKVSGT.DSY........VEGDDLHFLNNSAIQQLSDDIKRTIIVGMDTAHAVLEKRLGVEVTPETINNYMETINHALPGGAVVQEHMVEVHPGLVGDCYAKLFSGDDDLIDELDSRFLVDINKEFPEEQAEQLKDYIGKKTYQISRVPTMVVRACDGGTVSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVISMGSILP...............
Q2FSN0_METHJ/8-277                   ...............QKLFLKALK.T.KFE-G.DVADTKTGFYNFGGLNQSPRKKEFMEASKK.V.ELRR..GISMYDPNRCHL...gGLPMGQRQLMTYEVSGT.GTF........VEGDDLHFVNNPAMQQMWDDIRRTIIVNMDLAHQTLQKRLGKEITPETINEYLHILNHAMPGGAVVQEHMVETHPSVVDDCYVKVFTGDSELADQIEKQFVLDVNKLFPAKQAEQLNEAVGKSLWQAIHIPTIVSRTCDGGTTSRWSAMQIGMSFITAYRMCAGEAAVADLSFAAKHAGVIQMASHLP...............
D5EAD6_METMS/14-284                  .............ev--KFTKEHG.TnKMEGG.DITDMRIPYY-RLGVDQNPRKLEMKKVGKD.I.AEKR..GLAGYNP-MMHC...gGIPLGQRALTPSFISGNdDMM........VENDDLHYVNNAAMQQMWDDIRRTCIVGMDMAHETLEKRLSIEVTPETINHYLEVLNHALPGGAVVQEHMVESHPALVDDCYVKIFTGDDELADEIDDQFLIDIDKQFPAEQAEQLKASIGNTTWQAAHIPTIVSRTTDGGQTTRWTAMQIGMSYIAAYGMCAGEAAVADLSYAAKHAGVVNMGDMLP...............
A0A2I0PSL8_9EURY/10-278              ...............QKLFLKAMK.E.KFA-E.DPQATSTVF-ARAGLEQSPRKMEFMKAGKK.A.EMDR..GISMYDPKRCHC...gGIPLGQRQLMTYEVSGT.NVF........VEGDDLHFVNNAAMQQMWDDIRRTIIVGLDLAHNTLQKRLGKEVTPETINEYLHVLNHAMPGAAVVQEHMVETHPSLVDDCYVKIFTGDDEMADDIEPQFLLNLDKLFPAKSAAALKAAVGKSMFQAVHIPTTVSRTCDGGTTSRWSAMQIGMSFIGAYKMCAGEAAVADLAFAAKHAGVIQMADILP...............
M4YK22_THEXX/5-269                   ...............EKLFLEACK.K.KFK-E.EPTSMETKYYCYGGWKQSKSKVEFQKEAME.I.AKKR..GFPMMNEDV---....GVPLGQRSWMPYQLSHT.DIF........VEPDDLHCINNPAIQQAWDDIRRTVLVGLDSPHQTIEKRLGKEVTPETINAYLEAVNHTIPGGAIVQEHMAECNPALVYDSYVKVFSGNDELIDEIDPRFVIDINKNFPKDQAEKLKKAMGKTVMQAVRVPTMVGRVMDGATVSRHAAMQISMSFISSYKLAAGEAAIADFAYSAKHLS-INMGTMMP...............
A0A219ALM7_9EURY/3-268               ...............DKKFIDALN.K.KFK-E.SPEDKTTTFYNLGGWRQSERKTEFYEAGKE.I.AKKR..GIPQFNPDV---....GSPLGQRTLMPYQLSGT.DTF........VEGDDLHFVNNAAIQQMWDDIRRTVIVGLNTAHNVLERRLGMEVTPETITRYLETVNHAMPGGAVVQEHMVEINPYLAVDSYVKVFTGDDELADEIDKCYVLDINKEFPEEQAAALKAEVGDKIWQTVRIPSVVGRVCDGGVTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVIQMGTPLP...............
B8GE93_METPE/8-277                   ...............QKLFLKALK.E.KFAGE.DPAGEHTHF-ARAGLEQSERKREFMKEGKK.V.EMER..GISQYDPKRCHL...gGIPLGQRQLMTYEISGT.GTF........VEGDDLHFVNNAAMQQMWDDIRRTIIVGMDLAHNTLQKRLGKEVTPETINEYLHILNHAMPGAAVVQEHMVETHPSLVSDCYVKVFTGDDEVADQIEPQYLLNIEKLFPAKSAEKLKAAVGKSMFQAIHIPTTVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSYAAKHAGVIQMADILP...............
F6D2D3_METPW/3-268                   ...............DKKFIDALN.K.KFK-E.DPEEKKTTFYSFGGWKQSERKREFVEAGKK.I.AAER..GIPQYNPDV---....GTPLGQRVLMPYQVSTT.DTF........VEGDDLHFVNNAAMQQMWDDIRRTVIVGLDTAHNVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETNPALVADSYVKVFTGNDEIADEIDSAYVLDINKMFPEEQAEVLKAEVGDGIWQAVRIPTIVSRTCDGGTTSRWSAMQIGMSMISAYKQCAGEAATGDFAFAAKHAAVIHMGTALP...............
MCRA_METKA/6-271                     ...............EKLFMKALK.E.KFE-E.SPEEKYTKFYIFGGWKQSERKKEFKEWADK.I.VEER..GVPHYNPDI---....GVPLGQRKLMSYQVSGT.DVF........VEGDDLHFVNNAAMQQMWDDIRRTVIVGMDTAHRVLERRLGKEVTPETINEYMETLNHALPGGAVVQEHMVEIHPGLTWDCYAKIITGDLELADEIDDKFLIDIEKLFPEEQAEQLIKAIGNRTYQVCRMPTIVGHVCDGATMYRWAAMQIAMSFICAYKIAAGEAAVSDFAFASKHAEVINMGEMLP...............
#=GR MCRA_METKA/6-271          SS    ...............XX--HHHHH.H.H-S-S.-TT--B---S-S-GGGG-HHHHHHHHHHHH.H.HHHH..-S----TTS---....S--S-SS---EEEBTTS.--E........EEGGGSSGGG-HHHHHHHHHHHTEEEEE-HHHHHHHHHTT-----HHHHHHHHHHHHHHTTT--SS-TT-----TTT-TT-EEEEEES-HHHHTTS-GGGB--HHHHS-HHHHHHHHHHH-S-EEEEEE--HHHHHHS-HHHHHHHHHHHHHHHHHHHHT--SS-TTHHHHHHHHHTTSEEES---B-...............
A0A166C196_9EURY/3-268               ...............DKKFLDAMK.Q.KFS-E.DPTEKRTQFYNMGGWKQSERKTAFVNEGKK.I.AEER..GIPMYNPDI---....GTPLGQRALMSYQLSTT.DTF........VEGDDLHFINNSAIQQAWDDIRKTVIVGLNTAHNVLEKRLGIEVTPETITHYLETVNHAMPGAAVVQEHMVETDPLVVSDSYVKVFTGDDELADEIDSAFVLDINKEFPEEQAEALKAEVGGSVWQAVRIPAIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVIHMGTYLP...............
A5ULM9_METS3/5-271                   ...............EKVFFKALN.Q.KFKGE.DNESNHTSFYCFDGWKQSPRKREFNDAAEK.L.AKDR..NMPFYNPDI---....GVPLGQRSLMTYKISGT.DDY........VEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGLVSDCYAKIFTGNDELADEIDKRVLIDINKEFPEDQAQMLKDYLGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFINAYKLCAGEAAIADFSYAAKHADVIGMASFLP...............
U6EF81_9EURY/5-270                   ...............KKLFLKALQ.N.KFD-E.DPKQNHTNFYCFGGWKQSPRKKEFDEFAKK.I.EEDR..GIPFYNPDI---....GVPLGQRKLMAYKVSGT.DTY........VEGDDLHFCNNAAIQQLNDDIKRTIIVGMDTAHSVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGLVGDCYAKLFTGDDSLADELDSRYLIDINKEFPEEQAKQLKEYIGNKTYQISRVPSLVVRVCDGGTVSRWSAMQIGMSFIAAYKLCAGEAAIADFSYAAKHADVISMGSILP...............
A0A1F2P3I8_9EURY/2-269               ............dee---ILEKFK.E.IFRED.DPTRRKTRFYEFGGRMQSKRKREFIEASKR.I.AEER..GIPGYQGDREDL....GVPLGARYLEPYYISGT.DTI........CDMDDIHQINNAAIQQLGDDIKRTAINGLDLPHRILQQKVGVTVTPETINRYLESINHSLVGGALAQEHMAEINPLMTRDGYAKVITGDDELADALDKRFLIDINREFPEEMAEKLKDKIGNHLYQVSRIPTIGVRIADGSIVHRWNGNQSALAFVSAYKLGGG-SILAEFTITVKHMAYMLLG----tqt............
MCRA_METTH/3-268                     ...............DKLFINALK.K.KFE-E.SPEEKKTTFYTLGGWKQSERKTEFVNAGKE.V.AAKR..GIPQYNPDI---....GTPLGQRVLMPYQVSTT.DTF........VEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLP...............
U6EEP1_9EURY/3-268                   ...............EKMFINALK.K.AFE-E.DPSDKTTTFYKFGGWRQSERKREFVEAGKE.V.AAKR..GIPQYDPDV---....GTPLGQRVLMPYQVSTT.DTF........VEGDDLHFVNNAAMQQFWDDIRRTVIVGLNTAHSVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPLLTADSYVKVFTGNDEIADEIDQRYVLDINEEFPEHQAEVLKAEVGDGMWTVVRIPTIVSRTCDGGTTSRWSAMQVGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLP...............
A0A120K0D9_9EURY/3-268               ...............DKKFLDAMK.K.KFV-E.DPTEKTTQFYNMGGWTQSERKTAFVNEGKE.I.AEKR..GIPMYNPDI---....GSPLGQRALMSYQLSTT.DTF........VEGDDLHYINNAAIQQAWDDIRRTVIVGLNTAHNVLEKRLGIEVTPETITNYLETVNHAMPGAAVVQEHMVETDPLVVADSYVKVFTGDDELADEIDSAFVLDINKEFPEDQAEALKAEVGGAIWQAVRIPSIVGRVCDGGNTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVVHMGTYLP...............
A0A2I0P7B3_9EURY/8-278               ...............QKLFLKALK.E.KFQGQ.DVQSETTEFYKFNGYHQSPRKEEFVKASRA.I.ELDR..GISMYDPVRNHL...gGIPLGQRQLMTYEVSGT.GVF........VEGDDLHFVNNAAMQQMWDDIRRTVIVNMDLAHQTLQKRLGKEVTPETINEYLHVLNHAMPGAAVVQEHMVETHPGLVDDCYVKVFTGDQELADDLEPQFVLDVEKLFPGKQAEALSAAVGKSLWQAIHIPTTVVRTCDGGTTSRWSAMQIGMSFIGAYRMCAGEAAVADLSYAAKHAGVIQMASHLP...............
A7I5T9_METB6/10-278                  ...............QKLFLKAMK.E.KFA-E.DPQATSTVF-ARAGLEQSPRKMEFLKEGQK.V.ALDR..GISMYDPKRCHC...gGIPLGQRQLMTYEVSGT.GVF........VEGDDLHFVNNAAMQQMWDDIRRTIIVSLDLAHGTLQKRLGKEVTPETINEYLHVLNHAMPGAAVVQEHMVETHPALVDDCYVKIFTGDDEMADDIEPQFVLNLDKLFPAKQAAALKAAVGKSMWQAVHIPTTVSRTCDGGTTSRWSAMQIGMSFIGAYKMCAGEAAVSDLAFAAKHAGVIQMADILP...............
R9TAZ9_METII/3-268                   ...............DKLFMDAMK.K.KFK-E.DPTDEYTSYYTFGGWKQSKRKREWVEQANA.I.AKAR..GIPMMNQDI---....GVPLGQRVLMPYQLSHT.DMY........AEADDLHFVNNAAIQQAWDDIRRTVIVGLDTAHTVIEKRLGKEVTPETINNYLETVNHAMPGGAVVQEHMAECSPALTADCYVKVFSGNSELIDQLDKRFVIDINKEFPEDQAKQLNDAIGKSLYQVVRCPTIVGRVCDGGTMSRWSAMQISMSFISAYRLAAGEAAIADFAYAAKHASVVEMGTMMP...............
K4MC35_9EURY/14-283                  .............ei--KFTKEHG.SnKMQGG.EITDMVGKYY-RLGVEQNPRKVEMKKAGQE.I.AKKR..GLVGYNP-MMHC...gGIPLGQRALTPSFISGT.DMM........VEIDDLHYVNNAAMQQMWDDIRRTVVVGMDMAHETLEKRLGIEVTPETINHYLETLNHALPGGAVVQEHMVETHPALVDDCYVKVFTGDDELADEIDKQFLIDINKQFPAEQAETIKAAIGKTSWQAAHIPTIVSRVTDGAQTSRWMAMQVGMSFISAYSMCAGEAAVADLSYAAKHAGVLSMGEMLP...............
Q6LWZ5_METMP/5-272                   ..............k-RLFLKALK.E.KFE-E.DPKEKYTKFYTFGGWEQSARKREFVEANEK.I.VSEKrqGIPLYNPDI---....GVPLGQRKLMPYKLSNT.DDY........CEGDDLHFLNNAAIQQLWDDIRRTVIVGMDTAHSVLEKRLGVEVTPETINEYMHTINHSLPGGAVVQEHMVEVHPSLAWDCYARIFTGDDELADELDSRFLIDINKLFPEEQAETLKAAIGKKTYQVSRVPSLVGRVCDGGTISRWSAMQIGMSFITAYKLCAGEAATADFSYASKHADVIQMGNALP...............
A6UWH2_META3/5-271                   ...............KKLFLKALK.E.KFD-E.DPKEKYTKFYTYGGWKQSKRKTEFVEAAKD.I.ADKR.gGMPGYNPDI---....GVPLGQRKMMSYKLSGT.DDY........VEGDDLHFMNNAAIQQLHDDIRRTVIVGMDTGHMVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVDPALAWDSYAKIFTGDDELADELDKRVLVDINKLFPEEQAEELKAAIGKKTYQISRVPTLVGRVCDGGTIARWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIGMGTALP...............
F4BXY1_METSG/7-276                   ...............KKLFVKALN.K.KFGKDfDLASQKVEY-KRLGPEQNARKREFMEYAKK.L.EGKR..GMTGYNP-YVHA...gGIPLGQRQLVPYKLSST.EYV........VEGDDLHFVNNPAMQQFWDDIRRTIVVGLDMAHEVLQKRLGKEVTPETINNYLEILNHAMPGAAVVQEHMVETHPGLVDDCNVRVFSGDDALADEIDDQYKIDINKMFPEDQAETLKAAIGKTTWQAIHVPTIVVRTCDGGTTSRWSAMQLCMTFIDAYNMCAGEAAVADLAYAAKHAAVLQMSDMLP...............
A0A062V7W6_9EURY/13-283              kyakewgtnkcgsta---------.-.---KS.KITDKKTKY-LRLGYTQNPRKVEMTKCGAA.I.TKKR..GLQAYDPKL-HL...aGIPMGQRQLTPYTISGT.DIV........CDGDDLHFVNNAAMQQEWDDIRRTCIVGLDLAHETLEKRLGKEVTPETINYYLEVLNHAMPGAAIVQEHMVETHPALVDDCYVKVFTGDETLQDEIDKQFVINIDNEFPAEQAKQIKAGIGKTSWQAVHIPTIVTRTEDGPGTSRWMAMQVGMTFISAYHMCAGEAAVGELAFTAKHAGLVEMSDMIP...............
A0A1D2WBA8_9EURY/3-268               ...............DKKFMEALK.K.KFE-E.APEESKTHFYDLGGWKQSERKTEFVKAGKE.I.AEKR..GIPMYNPDV---....GTPLGQRVLMPYQVSTT.DTY........VEGDDLHFVNNAAMQQFWDDIRRTVIVGLNTAHNVIEKRLGKEVTPETITTYLETVNHAMPGAAVVQEHMVETNPSLVYDSYVKIFTGNDEIADEIDPAFVININKMFPEEQAEVLKAEVGDAMWQVVRIPTIVSRTCDGGTTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVVHMGSYLP...............
F0T8R3_METLA/3-268                   ...............EKMFIDALK.K.AFK-E.DPTDDKTTFYNKGGWKQSERKREFVAAGKD.I.AAKR..GIPMYDPDV---....GTPLGQRVLMPYQVSTT.DTF........VEGDDLHFVNNAAMQQFWDDIRRTVIVGMNTAHMVIEKRLGKEVSPETITNYLETVNHAMPGAAVVQEHMVETNPYLVADSYVKTFTGNDEIADEIDPAYVLNINKMFNEEQAEVLKAEVGDGIWQVVRIPTIVSRTCDGGTTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVVHMGTALP...............
A0A166A6T9_9EURY/3-268               ...............DKKFIQALD.K.KFK-E.APEDKTTTFYNLGGWKQSERKTEFYNAGKE.I.AEKR..GIPQYNPDV---....GSPLGQRTLMPYQVSTT.DTY........VEGDDFHFVNNAAIQQMWDDIRRTVVVGLNTAHTVLEKRLGIEVTPETITNYLETVNHAMPGAAVVQEHMVETNPLLVADSYVKVFTGDDELADEIDSAFVLDINKEFPEDQAAVLKEEVGDKIWQVVRIPSIVGRVCDGGTTSRWSAMQIGMSMISSYNQCAGEGATGDFAYASKHAEVIHMGTYLP...............
Q2NHZ8_METST/5-271                   ...............KKLFLKALK.E.KFD-E.DPEEENTKFYCYGGWEQSARKREFAEEAEK.A.VEAR.gGLPFYNPDI---....GVPLGQRKLMAYQVSGT.DTY........VEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLEQRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGLVTDSYAKIFTGDDDLLDQLDQRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVISMASAMP...............
A0A1D2WLQ3_9EURY/5-271               ..............n-KKFLSALN.K.KFKGE.DQENDHTSFYCFDGWKQSARKREFNEAAEK.L.AKER..NIPFYNPDI---....GVPLGQRQLMAYKISGT.EDY........VEGDDLHFCNNSAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGLVDDCYAKIFTGNDDLADELDKRLLIDINKEFPEEQAEMLKSYVGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFINAYKLCAGEAAIADFSYAAKHADVIGMGAFLP...............
A0A0P8CBK4_9EURY/10-279              .............et--KYTKEWG.S.NKNKGgKITDKKAKY-LRLGYQQNPRKVEMAKCGAA.I.TKKR..GLQAYDPKL-HL...aGIPMGQRQLTPYTISGT.DIV........CDGDDLHFVNNAAMQQEWDDIRRSCVVGLDLAHEVLEKRLGKEVTPETINYYLEVLNHAMPGAAIVQEHMVETHPALVDDCYVKIFTGDETLQDEVDKQFVINIDNEFPANQAKQIKAAVGKTSWQAVHIPTIVTRTEDGPGTSRWMAMQVGMTFISAYHMCAGEAAVGELAFTAKHAGLVEMGDMIP...............
A0A0W7TIP2_9EURY/7-271               ...............EKLFLEACK.K.KFK-E.APTDIETKYYCYGGWHQSKSKVEFQKEAME.I.AKKR..GFPMMNEDI---....GVPLGQRAWMPYQLSHT.DIF........VEPDDLHCINNPAIQQAWDDIRRTVLVGLDSPHNTIQKRLGKEVTPETINAYLETVNHTMPGGAVVQEHMAECNPALVYDSYVKVFSGDDELIDELDPRFVIDINKNFPKDQAEQLKKAMGKTVMQAVRVPTMVGRLMDGATVSRHAAMQISMAFISSYKLAAGEAAIADFAYSAKHQS-ITMGSMMP...............
L0HD22_METFS/10-280                  ...............QKQFLKALK.E.KFKGQ.DVESQKTGFYKFGGVQQSPRKREFMAATKK.I.EADR..GISMYDPEHCHL...nGIPMGQRQLMTYEVSGT.GTF........VEGDDLHYVNNSAIQQMSDEIKRTIIVGMDIAHNTLQKRLGKEVTPQTINEYLHILNHAMPGGAVVQEHMVETNPGLVDDCYVKIFTGNDEVADDIEPQYLLNIEKLFPKKQAEALKAEIGKSMYQAIHVPTIVVRTCDGGTTSRWSAMQIGMSFIAAYRTCAGEAAVADLSFAAKHAGVIQMGSHLP...............
D7DUH5_METV3/5-272                   ..............k-RLFLKALK.E.KFE-E.DPKEKFTKFYTYGGWQQSERKKEFFAENER.IvAEKR.dGIPMYNPDI---....GVPLGQRKLMPYKVSNT.DSY........VEGDDLHFMNNAAIQQLWDDIRRTVIVGMDTAHMVLEKRLGVEVTPETINEYMHTINHSLPGGAVVQEHMVEVHPSLAWDCYAKIFTGDDELADELDDRFVININKLFPEEQAEELKAAIGKKTYQVSRVPSLVGRVCDGGTISRWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMGNALP...............
A0A124G584_9EURY/8-278               ...............QKLFLKALK.E.KFPGQ.DVESQKAKFYAFDGLNQSPRKKEFMAENAK.I.VKER..GIDMYDPTRCHL...gGIPMGQRQLMTYEVSGT.GTF........VEGDDLHFVNNAAMQQFWDDIRRTVIVNMDLAHQTLQKRLGKEVTPETINEYLHVVNHAMPGAAVVQEHMVETHPALTDDCYVKVFTGDSELADDIEPQFLLNVEKLFPKKQAEALINAVGKSMWQCVHIPTTVSRTCDGGTTSRWSAMQIGMSFIGAYRMCAGEAAVADLSYAAKHAGVIQMASHLP...............
D1YVW6_METPS/7-275                   ...............QKRFIKAMK.K.KFAGE.DPTSTTTVY-KYEGYTQSKRKVEFKKAGDA.I.AKKR..GISAYNP-MVHM...gGIPLGQRQLTPYVVSGT.DVV........VEGDDLHFVNNAAMQQFWDEIRRTVIVGLDTAHATLEKRLGKTVTPETISNYLAILNHAMPGAAVVQEHMVETNPALTDDCFVKVFTGDDELADSIDKQYVLDINKAFPKDQAAALKKAVGKSLYQAVHIPTTVVRTCDGGTTSRWSAMQIGMSFIDAYKMCAGEAAVADLAFAAKHASLVEMADILP...............
L0HIJ7_METFS/11-279                  ...............QKLFLKAMK.E.KFA-E.DPQAQATVF-KREGLSQSPRKMEFVKAGKA.A.EMDR..GISMYDPARCHC...gGIPLGQRQLMTYEISST.GVF........VEGDDCHFVNNAAMQQMWDDIRRTIIVGLDLAHGTLQKRLGKEVTPETINEYLHVLNHAMPGAAVVQEHMVETHPSLVDDCYVKVFTGDDEMADDLEPQFVLNVDKLFPAKQAAQLKAAVGKSMWQAVHIPTIVSRTCDGGTTSRWSAMQIGMSFIGAYKMCAGEAAVADLAFAAKHAGVIQMADILP...............
J0RY59_9EURY/8-278                   ...............QKLFLKALK.E.KFQGQ.DVQSEKAEFYKFGGLKQSPRKQEFLKESRA.V.EMQR..GISMYDPERCHL...gGIPMGQRQLMTYEVSGT.GVF........VEGDDLHFVNNAAMQQFWDDIRRTIIVGMDLAHATLQKRLGKEVTPETINEYLHILNHAMPGAAVVQEHMVETHPALTDDCYVKVFTGDDELADDIEPQFLLNIEKLFPAKSAEALKAAVGKSMFQAVHIPTIVSRTCDGGTTSRWSAMQLGMSYIAAYRMCAGEAAVADLSYAAKHAGVIQMADILP...............
G7WN24_METH6/7-276                   ...............KKLFVKALN.K.KFGRDfDLSGTKTVY-ERLGPEQNARKREFMEASKK.L.EGKR..GISMYNP-YLHA...gGVPLGQRQLVPYKLSTT.EYI........VEGDDLHFVNNPAMQQMWDDIRRTIVVGLDMAHEVLEKRLGKEVTPETINNYLEILNHAMPGAAVVQEHMVETHPALVDDCNVRMFTGDDDLADEIDDQYLIDVNKLFPAEQAEEIKAAMGKTSWQAIHIPTIVSRTCDGGTTSRWSAMQLSMTFIDAYNMCAGEAAVADLAFAAKHAAVIQMADMLP...............
F7XL13_METZD/14-283                  ..............e-IKFTKEFG.D.NKQSGgSITDTRNKY-HRLGVDQDPRKREMREAGQK.V.AKER..GLVGYNP-MMHC...gGIPLGQRAITPSFVSGT.DIM........VEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGMEVTPETINHYLEVLNHALPGGAVVQEYMVETHPALVDDCYVKIFTGDDDLADEIDKQFLIDINKEFPEEQAEQLKKSIGKTTWQAAHIPTIVSRTTDGGQTSRWIAMQVGMSFISAYNMCAGEAAVADLSYSAKHAAVVSMGDMLP...............
A0A1V6N4K9_9EURY/3-268               ...............DKKFIEALN.K.KFK-E.DPEEKTTTFYNLGGWKQSERKTEFANAGKE.I.AEKR..GIPQYNPDV---....GSPLGQRALMPYQVSTT.DTY........VEGDDFHFVNNAAIQQMWDDIRRTVIVGLNTAHNVLEKRLGMEVTPETITEYLETVNHAMPGAAVVQEHMVETNPSLVADSYVKVFTGDDELADEIDSAFVLDINKEFPEDQAEALKAEVGDKVWQAVRIPTIVGRVCDGGTTSRWSAMQIGMSMISAYNQCAGEGATGDFAYASKHAEVIHMGTYLP...............
J0SAE9_9EURY/8-278                   ...............QKLFLKALK.E.KFQGQ.DVQSEKTEFYKFGGVRQSQRKLEFMKESRS.I.EMQR..GISMYDPERCHL...gGIPMGQRQLMTYEVSGT.GVF........VEGDDLHFVNNSAMQQMWDEIRRTVIVGMDMAHATLQKRLGKEVTPETINEYLHILNHAMPGGAVVQEHMVETHPALTDDCYVKVFTGDDELADEIDAQYLINIEKLFPKKQAEELKAEVGKSMFQAIHIPSIVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSYAAKHAGVIQMGSILP...............
A0A0E3SNQ2_METBA/14-282              ..............e-VKFAQEFG.S.NKQTGgDITGKTEKF-LRLGPEQDPRKVEMIKAGKE.I.AEKR..GIAFYNP-MMHS....GAPLGQRAITPYTISGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCVVGLDMAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQEMMVETHPALVDDCYVKVFTGDDALADEIDKQFLIDINKEFSEEQAAQIKASIGKTSWQAIHIPTIVSRTTDGAQTPRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
A0A0F8E165_9EURY/14-282              ..............e-VKFTQEYG.S.NQQSTtDITGKTEKF-LRLGPAQDARKAEMIKAGKE.L.AEKR..GLAFYNP-MMHT....GAPLGQRAITPYVISGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLETLNHAMPGAAVVQEMMVETHPALVDDCYVKIFTGDDELADEIDKQYLININKMFNEEQAAQIKASVGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYNMCAGEAAVADLSFAAKHAALVSMGEMLP...............
A0A1F2P6A2_9EURY/2-269               ..............e-KKSIDIIK.E.IFGEE.DAESKHTSFYEFGGWRQSRRKREYVEIARD.L.VKKR..GVTGYQGDRDDM....GVPLGQRFIEPYYISGT.DIL........CDAEDLHQINNAAIQQMGDDIKRTAISGLDMAHRMLEVRIGATVTPETINRYLEVANHTIVGGAVAQEHMAEINPAMTRDGYVKITTGNEDLTDHIDKQYLIDINMEYPEDQADALKEGVGSSLYQVVRVPTIAVRNADGGITHRWAANQCTLAFITAYALGGG-SVLADFSLTSKHMQYVTLGT---pt.............
A0A1F2PC64_9EURY/2-269               ..............k-KKAIDLLM.A.TFDED.DATREYTTFFQFGGWKQSKRKQEYVKLAKE.L.LKER..GLTGYQGDRDDM....GVPLGQRFIEPYYISGT.ETM........CEAEDLHQINNAAMQQLGDDIKRTAIAGLDMAHKMLEVRIGATVTPETINRYLEVANHTIVGGAVAQEHMPEINPAMTKDASVKLMSGNDELLDHIDDQYIIDIDKEYPEKQAEDLKEGIGKRLFQATRIPTIAVRISDAGIVHRWAANQTTLAFITAYALG-GGAVLADFSLTSKHMQYVLLG----tps............
F6BE97_METIK/5-271                   ...............KKLFLKALK.E.KFE-E.DPKEKYTKFYVFGGWKQSARKREFVEAAEK.L.LEKR.gGIPFYNPDI---....GVPLGQRKLMPYKLSGT.DYI........VEGDDLHFMNNAAMQQMWDDIRRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPALAWDCYAKIFTGDDELADEIDKKFLIDINKLFPEEQAEQIKKAIGKRTYQVNRVPTLVGRVCDGGTIARWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMGTLLP...............
A0A1D2X2N6_9EURY/5-271               ...............KKLFLKALQ.E.KFD-E.DPKEENTKFYCYGGWEQSARKREFNEEAVK.A.MEER.dGLPFYNPDI---....GVPLGQRKLMAYQVSGT.DTY........VEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLEHRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGLVTDSYAKIFTGDDDLLDQLDQRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFISAYKLCAGEAAIADFSYAAKHADVISMASAMP...............
A0A1I4S1G7_9EURY/14-283              ............eik---YTKEHGtN.KMNGG.EITDKTVEYY-RLGVDQNPRKLEMKKAGKE.L.AEKR..GLVGYNP-MMHC...gGIPLGQRALTPSFLSGT.DDM........VEIDDLHYVNNAAMQQMWDDIRRTVIVGLDMAHETLEKRLGIEVTPETINHYLETLNHALPGGAVVQEHMVETHPALVDDCFVKIFTGDDELADEIDSQFLIDINKQFPAEQAEQLKAAIGKNSFQAAHIPTIVSRTTDGGQTSRWMAMQVGMAFISAYSMCAGEAAVADLSYAAKHAGVIQMGEMLP...............
Q8PXH8_METMA/14-282                  ..............e-VKFTQEYG.S.NQQAGgDITGKTAKF-LRLGPEQDARKAEMIKAGKE.I.AEKR..GIAFYNP-MMHS....GAPLGQRAITPYTLSGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQEMMVETHPALVDDCYVKVFTGDDELADEIDKQYVININKMFSEEQAAQIKASMGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
A0A0E3S2W5_9EURY/14-282              ..............e-VKFTQEYG.T.NQQSTtDITGKTEKF-LRLGPAQDARKAEMIKAGKE.I.AEKR..GISFYNP-MMHT....GAPLGQRAITPYTISGT.DMV........CEPDDLHYVNNAAMQQMWDDIRRTCIVGLDLAHETLEKRLGKEVTPETINHYLETLNHAMPGAAVVQEMMIETHPALVDDCYVKIFTGDDELADEIDKQYLININKMFTPEQAAQLKASVGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYNMCAGEAAVADLSFAAKHAALVSMGEMLP...............
D7E8X7_METEZ/15-284                  ...............ERKFTQEFG.D.NKQSGgEITDKKTEY-QRMGVAQSPRKMEMLKAGQE.L.SKKR..GLVGYNPDL-HA...gGVQLGQRALTPSYLSGT.DML........TEMDDLHYVNNAAMQQMWDDIRRTCIVGMDSAHETLEKRLGIEVTPETINHYLEVLNHAIPGGAVVQEHMVETHPGLTEDCYVKIFTGDDDLADEIDDQFLIDIDKEFPEDQAQQLKESIGKTTWQVAHIPTVVSRTTDGGQTRRWMAMQLGMSFINAYHMCAGEAAVADLSYAAKHASVINMGEMLP...............
A0A1D3L4K2_9EURY/3-268               ...............DKKFMEALN.K.KFK-E.APEEKKTTFYSFGGWKQSERKREFVEAGKE.V.AAKR..GIPQYNPDI---....GCPLGQRVLMPYQVSTT.DTF........VEGDDLHFVNNTAMQQFWDDIRRTVIVGLGTAHGVIEKRLGKEVSPETITNYLETVNHSMPGAAVVQEHMVETHPALVADSYVKIFTGNDEIADEIDSAFVIDINKMFPDEQAEVLKAEVGDGIWQAVRIPTIVSRTCDGGTTSRWSAMQIGMSMISAYKQCAGEAATGDFAFAAKHAEVIHMGTALP...............
F6BBJ2_METIK/5-270                   ...............KKLFLKALR.E.KFE-E.DPKEKYTKFYVFGGWKQSARKREFYEYAQK.I.AKER..GIPGYNPDI---....GVPLGQRKLMTYKISGT.DAF........VEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGLVWDCYAKIFTGNDELADEIDKRFLIDINKEFPEEQAEMLKRYIGNRTYQVSRVPTLVVRCCDGATVARWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMGTLLP...............
A0A150J824_9EURY/7-272               ..............k-HNFMQAMK.K.KFE-E.APDKKNTKYYVYGGYKQNKRKVEFHDAGLQ.I.AKER..GIPGYNPSV---....GMPQGQRVLMPYQLSHT.DII........ANMDDLHFVNNAAMQQAWDDMRRTILVGLDSPHNILEKRLGKEVTPETINHYLEVVNHAMPGAAVIQEHMVETDPRLVKDSYVKVYSGNDELIDEIDSRFVIDINKEFPAAQAAELKKAIGKSMWQVVRIPTVVGRICDGGTVSRWSAMQIGMAFIGAYNLCAGEAATGDFAYAAKHGSVIQMSDMMP...............
I7LMP5_METBM/8-278                   ...............QKMFLKALK.E.KFQGQ.DIESETAEFYKFNGVRQSPRKMEFMKASRA.I.EMDR..GISMYDPERCHL...gGIPMGQRQLMTYEVSGT.GVF........VEGDDLHYVNNSAMQQFWDDIRRTVIVGMDLAHQTLQKRLGKEVTPETINEYLHILNHAMPGAAVVQEHMVETHPGLVDDCYVKVFTGDDDVADDIEPQFLLNIEKLFPAKQAEELKAEVGKGMYQAIHIPTAVSRTCDGGTTSRWSAMQIGMSFIAAYRMCAGEAAVADLSFAAKHAGVVQMASLLP...............
A0A139CTB8_9EURY/14-283              .............ei--KFTKEHG.TnKMEGG.EITDKTVKYY-RLGVDQNPRKLEMKKAGAE.L.AKKR..GLVGYNP-MMHC...gGIPLGQRALTPSFLSGT.DMM........VEIDDLHYVNNSAMQQMWDDIRRSIVVGMDLAHETLEKRLGIEVTPETINHYLETLNHALPGGAVVQEHMVETHPALVDDCYVKMFTGDDELADEIDSQFLIDINKEFPEEQAEQIKEAIGKTSWQAAHIPTIVSRTTDGGQTSRWMAMQVGMSFISAYSMCAGEAAVADLSYAAKHAGVIQMGDMLP...............
A0A0E3NNS2_9EURY/14-282              ..............e-VKFTQEFG.S.NQQSTtDITGKTEKF-LRLGPAQDARKAEMIKAGKE.I.AEKR..GLVGYNP-MMHT....GAPLGQRAITPYTISGT.DIV........CEPDDLHYVNNSAMQQMWDDIRRTCIVGLDMAHETLEKRLGKEVTPETINHYLETLNHAMPGAAVVQEMMIETHPALVDDCYVKVFTGDDELADEIDKQYVININKMFNEEQAAQLKASIGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYNMCAGEAAVADLSFAAKHASLVSMGEMLP...............
A0A1E7GGH8_9EURY/14-282              ..............e-VKFTQEFG.T.NQQSTtDITGKTEKF-LRLGPTQDVRKAEMIKAGKE.I.AEKR..GIAFYNP-MMHT....GAPLGQRAITPYVISGT.DIV........AEPDDLHYVNNAAMQQMWDDIRRTCIVGLDLAHETLEKRLGKEVTPETINHYLEVLNHAMPGAAVVQEMMVETHPALVDDCYVKVFTGDDALADEIDKQFLININKEFSAEQAAQIKASIGKTTWQAIHIPTIVSRTTDGAQTSRWAAMQIGMSFISAYAMCAGEAAVADLSFAAKHAALVSMGEMLP...............
A0A1F2PDF7_9EURY/167-444             .......qramnesv-------LA.K.GFGVE.DVREETTEY-PAGGISQVPEKLEYVKVSKE.I.EKQR..GISLYRPHL-HW...hGIELGQKPYVKWKITAT.HMQrpcrtfdgLSMEQINFLNNAACHQWMADVQRTHIFGLDLAHRTVERRFGKEVTPDSINLYMEMHNHNIAAGSLIMEHIGETDPRLVADSYVKIITGNEAMLEVLDPQYIIDVRQLFPEYQASQIMNQIGDKLFEVARIPTLITMIGDHGTTRGWTGQQASLAFLSAYRIPAGEAVTSDFVYTVKHGDNIFMGNRLP...............
A0A1Y3GED3_9EURY/6-271               ..............s-KRFIKALK.N.KFE-E.EPTDTKTHFYDLGGYKQSERKKEFQERAAQ.I.AKER..GTPSLNEDI---....GVPLGQRVLMPYQLSHT.DTM........VEPDDLHIINNAAMQQAWDDIQRTVIVGLDTAHQVMEKRLGVEVTPETINEYLEVFNHTQPGGAVVQEHMAECNPGVTGDAYVKVFTGNDELADEIDDNLLIDINENFPEDQAEQLKEAIGDSLWQAIRAPTIVTRVMDGATIRRWAAMQSSMAFISSYSLCAGEAAIADFAYASKHSKVINMASAMP...............
#=GC SS_cons                         ..............HXHHHCCHHC.C.H-S-S.-TT-SEE--S-S-GGGGSHHHHHHHHHHHH.H.HHHH..TS----CTCGSS....SS-S-SS---EEEBTTS.--E........EEGGGCSGGG-HHHHHHHHHHHTEEEEESHHHHHHHHHCC-----HHHHHHHHHHHHHHTTT--SS-TT-----CCCSTT-EEEEEES-HHHHTTS-GGGB--HHHHS-HHHHHHHHHHH-S-EEEEEE--HHHHHHS-CCHHHHHHHHHHHHHHHHHCT--TT-CCHHHHHHHHHTTTEEESS--B-...............
#=GC seq_cons                        ................KhFlcAhc.c.KFp.-.DspscpTpFYphuGhcQStRKpEFhcsucc.I.AccR..GIshYNP-h.......GlPLGQRtLMsYplSGT.Dsh........VEuDDLHFVNNAAhQQhWDDIRRTlIVGlDhAHpsLEKRLGhEVTPETINcYLEslNHAMPGuAVVQEHMVETHPuLVsDsYVKlFTGDDELADEIDppFlIDINK.FPc-QAEpLKsulGKshaQsl+IPTlVuRsCDGGTTSRWSAMQIGMSFIoAYphCAGEAAlADhuYAAKHAsVIpMGshLP...............
//
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