#=GF ID   Pox_EPC_I2-L1
#=GF AC   PF12575.12
#=GF DE   Poxvirus entry protein complex L1 and I2
#=GF PI   DUF3753;
#=GF AU   Gavin OL;
#=GF SE   Prosite
#=GF GA   23.40 23.40;
#=GF TC   23.60 37.90;
#=GF NC   22.90 23.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR009175;
#=GF DR   TC; 1.G.11;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Pox_EPC_I2-L1 family of proteins is found in poxviruses.
#=GF CC   Proteins in this family are approximately 70 amino acids in
#=GF CC   length. There is a conserved YLK sequence motif.
#=GF SQ   39
#=GS I2_FOWPN/1-64          AC O72899.1
#=GS A0A2C9DT19_9POXV/1-64  AC A0A2C9DT19.1
#=GS Q070I5_CPRVZ/1-65      AC Q070I5.1
#=GS Q0GP16_HSPV/1-75       AC Q0GP16.1
#=GS A0A3F2YKK3_SHEVT/1-70  AC A0A3F2YKK3.1
#=GS G3EIC8_9POXV/1-67      AC G3EIC8.1
#=GS U3UBI1_9POXV/1-68      AC U3UBI1.1
#=GS A0A1C9HHA2_LSDV/1-71   AC A0A1C9HHA2.1
#=GS Q9DHR8_YLDV/1-72       AC Q9DHR8.1
#=GS A0A1B1MRE7_9POXV/1-70  AC A0A1B1MRE7.1
#=GS Q9Q8Q7_MYXVL/1-71      AC Q9Q8Q7.1
#=GS Q98213_MCV1/1-69       AC Q98213.1
#=GS I2_VACCW/1-72          AC P68606.1
#=GS Q6TUW9_YMTV5/1-70      AC Q6TUW9.1
#=GS Q775X2_CAMPS/1-72      AC Q775X2.1
#=GS M1L4Z5_MONPV/1-72      AC M1L4Z5.1
#=GS Q77TL7_VACCT/1-72      AC Q77TL7.1
#=GS A0A2U9QHL3_9POXV/1-68  AC A0A2U9QHL3.1
#=GS Q6VZN1_CNPV/1-68       AC Q6VZN1.1
#=GS A0A1L3IZG0_9POXV/1-73  AC A0A1L3IZG0.1
#=GS Q08FD0_DPV84/1-72      AC Q08FD0.1
#=GS Q0NPD7_9POXV/1-72      AC Q0NPD7.1
#=GS Q08FV0_DPV83/1-73      AC Q08FV0.1
#=GS I2_VACCC/1-72          AC P68604.1
#=GS I2_VAR67/1-72          AC P0DOR3.1
#=GS A0A6B9R341_9POXV/1-69  AC A0A6B9R341.1
#=GS A0A223FNA6_9POXV/1-67  AC A0A223FNA6.1
#=GS A0A223FMR9_9POXV/1-68  AC A0A223FMR9.1
#=GS A0A1V0S7V1_CNPV/1-65   AC A0A1V0S7V1.1
#=GS A0A220T6B1_9POXV/1-70  AC A0A220T6B1.1
#=GS A0A385H9L2_FOWPV/1-64  AC A0A385H9L2.1
#=GS Q9Q932_RFVKA/1-71      AC Q9Q932.1
#=GS D3IZH8_9POXV/1-70      AC D3IZH8.1
#=GS Q6TVT9_ORFSA/1-70      AC Q6TVT9.1
#=GS F1AWZ6_ORFV/1-70       AC F1AWZ6.1
#=GS Q8V3Q4_SWPV1/1-72      AC Q8V3Q4.1
#=GS B2CWE6_9POXV/1-71      AC B2CWE6.1
#=GS A0A097IVR7_9POXV/1-74  AC A0A097IVR7.1
#=GS H6TA36_9POXV/1-74      AC H6TA36.1
I2_FOWPN/1-64                     MEKLFTGTYGVFLESNDS.DF...EDFINTIMTVLTGKK...ESKQL------SW--.LTIFI.IFVVCIVVFTFLYLKL-m..
A0A2C9DT19_9POXV/1-64             MDRLKTGIFGVFIDSTED.DF...EDFINTVMAVLTEAK...PKYKINAA-------.LPAAL.LGLLLAAL-LFLYLKLV...
Q070I5_CPRVZ/1-65                 MDRLSAGLAGVFASNPDEsDL...DLFLDSVLSVMKDKK...PLFARTGT-------.LIFAI.VAAAIVLLLL-LYLKL-a..
Q0GP16_HSPV/1-75                  MDKLYAAIFGVYMGSPKD.DLtdlTDFIEIVKSVLSDEK...TTTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
A0A3F2YKK3_SHEVT/1-70             MDKLYSAIFGVFMSSSDD.DF...NNFINVVKSVLNNEN...YNKKTKKSFLRN--Y.LIIGL.VTIVFVIIFIIFYLKV-i..
G3EIC8_9POXV/1-67                 MDKLYAATFGVFTSSSEE.DL...NDFINIVKSVISDDK...KEKSRTNK-FNIW--.--IVL.IFIIIVILLIFLYLKV-y..
U3UBI1_9POXV/1-68                 MDKLCAAVFGVFISSSEE.DL...DGFVDVVTAVLADKP...VRKGPAGD---SWLP.YLLIG.LAVLIGVIAVMVY----avp
A0A1C9HHA2_LSDV/1-71              MDKLYSAIFGVFMSSSDD.DF...NNFINVVKSVLNDDE...NYNKKTKK-SFLRYY.LIIGL.VTIVFVIIFIIFYLKV-i..
Q9DHR8_YLDV/1-72                  MDKLYTAIFGVFLSSENE.DF...NNFIDVVKSVLSDDYdgvNKNNNCSSSTKIW--.-ILTI.IFVVFATFLTFLYLKA-i..
A0A1B1MRE7_9POXV/1-70             MNKLYTAIFGVYISNPDD.DF...EKFINAVKSVIVDDD...DTCKKKPCSLQSWIF.FVIIF.IIL--FISLVVLYLKL-t..
Q9Q8Q7_MYXVL/1-71                 MDKLYTALFGVFMTSTDD.DF...NNFIEVVKSVLTDKP...SYMPGISKGTTWWL-.VIIAV.AVVMCLVFFLMMYLKA-i..
Q98213_MCV1/1-69                  MERLYAGIFGVFMTTPED.DF...EEFLEVVQAVLTDSP...RAARRAPRAQSL---.LLFVL.FAALLAAILLFLYLKL-a..
I2_VACCW/1-72                     MDKLYAAIFGVFMGSPED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
Q6TUW9_YMTV5/1-70                 MDKLYTAIFGAFLSSEDE.DF...NNFIDVVRSVLTDDN..iASKNVCSSGTKIW--.-IITI.IFVVLAVFLTFLYLKAV...
Q775X2_CAMPS/1-72                 MDKLYAAIFGVFMGSPED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWSWYW.LIIIF.FIVLILLLLIYLYLKVV...
M1L4Z5_MONPV/1-72                 MDKLYAAIFGVFMGSQED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
Q77TL7_VACCT/1-72                 MDKLYAAIFGVFMGSPED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
A0A2U9QHL3_9POXV/1-68             MNNLFTTVFGVFISSSDD.DF...ENFINAIKTVMIDKE...SMESRNIY--S--LC.VVIFV.ICLLFISIFLFLYSKL-i..
Q6VZN1_CNPV/1-68                  MEKLLTGTYGVFLESSDS.DF...EEFIDTIMHVLVGKT...QPKKKSSL----SII.LIILL.ILITIIAVFTFLYLKL-m..
A0A1L3IZG0_9POXV/1-73             MDRLYAAIFGVFMSSTDD.EF...SKFIEVVKSVLSDEN...GGSKNKQQKSFFNFNiLLGLI.IFILLILFIVIFYLKVV...
Q08FD0_DPV84/1-72                 MDKLYAAIFGVFMSSTDD.DF...NNFIDVVKSVLSDED...SSKKIKSV-SWFNGQnFIFLI.FSLIIVALFSFFVFKG-y..
Q0NPD7_9POXV/1-72                 MDKLYAAIFGVFMGSPED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
Q08FV0_DPV83/1-73                 MDKLYAAIFGVFMSSTDD.DF...NNFIDVVKSVLSDED...GSKKTTKSVSWFNSQnFLFLI.FSLIIVSLFSFFVFKG-y..
I2_VACCC/1-72                     MDKLYAAIFGVFMGSPED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
I2_VAR67/1-72                     MDKLYAAIFGVFMGSPED.DL...TDFIEIVKSVLSDEK...TVTSTNNTGCWGWYW.LIIIF.FIVLILLLLIYLYLKVV...
A0A6B9R341_9POXV/1-69             MDKLYVTIFGTFLSSNEE.DL...DNFIDVVYSVLNNTE...TSLFSKII---INNK.VIILT.IILIIIPLIAFFYLKF-i..
A0A223FNA6_9POXV/1-67             MDKLYAAIFGVFTNSPED.DL...NDFIDIVKSVISDDD...RPKPAKRF--NIW--.LVLIF.IMVVVTILL-VLYLKV-y..
A0A223FMR9_9POXV/1-68             MDKLYAAIFGVFTNSPED.DL...NDFIDIVKSVISDDD...SRPKPAKR-FNIW--.LVLVF.IMVVVTILLV-LYLKV-y..
A0A1V0S7V1_CNPV/1-65              MEKLFTGTYGVFLESSDS.DF...EEFIDTIMHVLTGDT...QKKKKSSL-------.SIILI.ILFILIAFLTFLYLKL-m..
A0A220T6B1_9POXV/1-70             MDKLYASIFGVFISSADE.DF...NEFIDVVKSVISDEP..vKWKSNCTSSSKYW--.-IILF.IIVLVVIFLCFLYLKV-m..
A0A385H9L2_FOWPV/1-64             MEKLFTGTYGVFLESNDS.DF...EDFINTIMTVLTGKK...ESKQL------SW--.LTIFI.IFVVCIVVFTFLYLKL-m..
Q9Q932_RFVKA/1-71                 MDRLYTALFGVFMTSTDD.DF...NNFIEVVKSVLTDKK...SYTSGISNGTRWWL-.VIITV.VMVICLVFFLTMYLKVT...
D3IZH8_9POXV/1-70                 MDKLYAGVFGSFLSNSDE.DF...EEFLNIVRTVMTEKP...ACDRSKGV---PWTTvFLIGL.IAAAIGVLLCFHYLKLV...
Q6TVT9_ORFSA/1-70                 MDKLYTGVFGSFLSNSDE.DF...EEFLNIVRTVMTEKP...ACDRPKGV---PWTTvFLIGL.IAAAIGVLLCFHYLKLV...
F1AWZ6_ORFV/1-70                  MDKLYTGVFGSFLSNSDE.DF...DEFLNIVRSVLTEKP...ACDKPKGAPGTT--V.FLIGL.IAAAMGVLLCFHYLKLV...
Q8V3Q4_SWPV1/1-72                 MDKLYAAIFGVFMTSKDD.DF...NNFIEVVKSVLTDTS...SNHTISSSNNNTWIYiFLAIL.FGVMVLLVFI-LYLKVT...
B2CWE6_9POXV/1-71                 MDKLYTALFGVFMTSTDD.DF...NNFIEVVKSVLTDKP...SYMPGISKGTTWWL-.VIIAV.AVVMCLVFFLMMYLKA-i..
A0A097IVR7_9POXV/1-74             MDKLYAAIFGVFMSSTDD.EF...YKFIEVVKSVLSDGD...NNSNKNKIQKSFFNFnILLGLaIFILLILFVVIFYLKVV...
H6TA36_9POXV/1-74                 MDKLYAAIFGVFMSSTDD.EF...YKFIEVVKSVLSDGD...NNSNKNKIQKSFFNFnILLGLaIFILLILFVVIFYLKVV...
#=GC seq_cons                     MDKLYuAIFGVFhoSs-D.DF...scFI-lVKSVLoDcc...ssppsssp...hW...llIhl.lhllllllllaLYLKl....
//