GenomeNet

Database: Pfam
Entry: PF12844
LinkDB: PF12844
Original site: PF12844 
#=GF ID   HTH_19
#=GF AC   PF12844.7
#=GF DE   Helix-turn-helix domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Jackhmmer:Q180H4
#=GF GA   30.20 30.20;
#=GF TC   30.20 30.20;
#=GF NC   30.10 30.10;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Helix-turn-helix
#=GF DR   INTERPRO; IPR001387;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family contains a DNA-binding helix-turn-helix
#=GF CC   domain. This family contains many example antitoxins from
#=GF CC   bacterial toxin-antitoxin systems. These antitoxins are likely
#=GF CC   to be DNA-binding domains.
#=GF SQ   5804
#=GS B7K8E4_CYAP7/6-71         AC B7K8E4.1
#=GS A0A1I2NWR6_9FIRM/13-76    AC A0A1I2NWR6.1
#=GS A1T387_MYCVP/7-70         AC A1T387.1
#=GS A0A1X9LNF4_9MICO/24-85    AC A0A1X9LNF4.1
#=GS Q185V4_PEPD6/8-71         AC Q185V4.1
#=GS A0A1A7QRL5_9FLAO/4-64     AC A0A1A7QRL5.1
#=GS T0CX33_PAESO/8-74         AC T0CX33.1
#=GS R7M4I9_9CLOT/7-70         AC R7M4I9.1
#=GS Q8A1B0_BACTN/9-71         AC Q8A1B0.1
#=GS M4R801_BIBTR/1-58         AC M4R801.1
#=GS R8P3Q8_BACCE/4-66         AC R8P3Q8.1
#=GS A0A1H9YKF7_9FIRM/2-65     AC A0A1H9YKF7.1
#=GS S5RKV4_9STRE/4-66         AC S5RKV4.1
#=GS A0A1B0T6B2_9CAUD/4-67     AC A0A1B0T6B2.1
#=GS K0B275_CLOA9/3-65         AC K0B275.1
#=GS C4IDX5_CLOBU/7-69         AC C4IDX5.1
#=GS R6NVH7_9FIRM/4-65         AC R6NVH7.1
#=GS Q1JXW4_DESA6/9-70         AC Q1JXW4.1
#=GS A0A1M6M2F9_9BACL/5-66     AC A0A1M6M2F9.1
#=GS A0A0A8JL40_BACSX/4-77     AC A0A0A8JL40.1
#=GS B0S078_FINM2/4-68         AC B0S078.1
#=GS A0A1F2PNE2_9FIRM/5-68     AC A0A1F2PNE2.1
#=GS A0A1I4QWD1_9BACI/7-67     AC A0A1I4QWD1.1
#=GS F5J1J5_9BACT/14-76        AC F5J1J5.1
#=GS E3GEJ9_EUBLK/4-67         AC E3GEJ9.1
#=GS W9H692_9PROT/8-70         AC W9H692.1
#=GS A0A0S2W6B7_9FIRM/8-70     AC A0A0S2W6B7.1
#=GS A0A1I3MG08_9BACL/10-72    AC A0A1I3MG08.1
#=GS A0A1Q9PPC6_9BACI/4-67     AC A0A1Q9PPC6.1
#=GS A0A212TT77_9ACTN/6-73     AC A0A212TT77.1
#=GS A0A1F6RD80_9BACT/37-91    AC A0A1F6RD80.1
#=GS A0A1M6WVG3_9BACL/6-67     AC A0A1M6WVG3.1
#=GS A0A0R2M803_9LACO/4-74     AC A0A0R2M803.1
#=GS R5VNI5_9FIRM/4-67         AC R5VNI5.1
#=GS B0UFY6_METS4/23-84        AC B0UFY6.1
#=GS A0A1G6CL20_9FIRM/8-71     AC A0A1G6CL20.1
#=GS A0A1H8F3E5_9BACT/9-71     AC A0A1H8F3E5.1
#=GS Q839M1_ENTFA/25-79        AC Q839M1.1
#=GS A0A1E5KV29_9ENTE/4-66     AC A0A1E5KV29.1
#=GS A0A1F6PNW9_9BACT/8-69     AC A0A1F6PNW9.1
#=GS R5XA80_9CLOT/4-67         AC R5XA80.1
#=GS A0A161RB63_9FIRM/3-62     AC A0A161RB63.1
#=GS S6F8K4_9CLOT/1-58         AC S6F8K4.1
#=GS A0A1S5S9V0_9VIRU/6-66     AC A0A1S5S9V0.1
#=GS A0A1V9EYP9_9BACT/15-75    AC A0A1V9EYP9.1
#=GS R6GVB7_9FIRM/8-72         AC R6GVB7.1
#=GS A0A095S6Y3_9GAMM/4-67     AC A0A095S6Y3.1
#=GS R7DDU4_9BACT/7-70         AC R7DDU4.1
#=GS R5A3P2_9CLOT/4-66         AC R5A3P2.1
#=GS C8VZT4_DESAS/9-64         AC C8VZT4.1
#=GS A0A090APF8_9GAMM/4-67     AC A0A090APF8.1
#=GS A0A0B8T8J3_9SPHI/11-73    AC A0A0B8T8J3.1
#=GS A0A1M4SWR2_9RHOB/8-71     AC A0A1M4SWR2.1
#=GS A0A143G3Q2_9GAMM/55-107   AC A0A143G3Q2.1
#=GS A0A0D6PF31_9PROT/29-90    AC A0A0D6PF31.1
#=GS A0A1V2B1V8_9BACT/4-66     AC A0A1V2B1V8.1
#=GS A0A1I7CBZ1_9BACT/9-73     AC A0A1I7CBZ1.1
#=GS A0A0Q6BAV1_9PROT/6-73     AC A0A0Q6BAV1.1
#=GS A0A1F8TNZ5_9CHLR/17-79    AC A0A1F8TNZ5.1
#=GS A0A1N7PBL0_9FLAO/4-66     AC A0A1N7PBL0.1
#=GS A0A267T5S2_9BACT/15-77    AC A0A267T5S2.1
#=GS A1ZJY8_9BACT/4-68         AC A1ZJY8.1
#=GS K5ACP0_PAEAL/2-65         AC K5ACP0.1
#=GS A0A177LA02_9BACI/12-70    AC A0A177LA02.1
#=GS A0A1M6LSE0_9CLOT/4-68     AC A0A1M6LSE0.1
#=GS F4G8T8_ALIDK/4-66         AC F4G8T8.1
#=GS A0A109CIF2_9BURK/5-67     AC A0A109CIF2.1
#=GS R7NHI1_9MOLU/99-160       AC R7NHI1.1
#=GS A0A1G6SWL7_9PSEU/6-68     AC A0A1G6SWL7.1
#=GS A0A1G0N021_9DELT/10-73    AC A0A1G0N021.1
#=GS F1YY62_9STRE/2-63         AC F1YY62.1
#=GS A5FKS5_FLAJ1/11-73        AC A5FKS5.1
#=GS A0A162QIF8_9CLOT/5-74     AC A0A162QIF8.1
#=GS A0A0F0C618_9CLOT/6-69     AC A0A0F0C618.1
#=GS A0A1G4FFV1_9FIRM/4-68     AC A0A1G4FFV1.1
#=GS A0A0Q0Y3J1_LEULA/4-67     AC A0A0Q0Y3J1.1
#=GS L0IRY0_9MYCO/7-70         AC L0IRY0.1
#=GS H5UJF9_9ACTN/12-74        AC H5UJF9.1
#=GS R7NGP5_9MOLU/7-70         AC R7NGP5.1
#=GS A0A1G9MYJ1_9FLAO/4-67     AC A0A1G9MYJ1.1
#=GS A0A264W305_9BACL/6-65     AC A0A264W305.1
#=GS A0A285ULY2_9RHIZ/13-77    AC A0A285ULY2.1
#=GS R7GH17_9CLOT/15-83        AC R7GH17.1
#=GS A0A1C7GPX2_9FIRM/38-100   AC A0A1C7GPX2.2
#=GS A0A1M6AWJ2_9RHOB/18-80    AC A0A1M6AWJ2.1
#=GS A0A1M6HCU3_9CLOT/8-68     AC A0A1M6HCU3.1
#=GS A0A1Q6TDU4_9FIRM/15-82    AC A0A1Q6TDU4.1
#=GS E6UDE9_RUMA7/7-67         AC E6UDE9.1
#=GS A0A286GYK1_9PROT/6-67     AC A0A286GYK1.1
#=GS A0A1H0KZN1_HALAD/3-67     AC A0A1H0KZN1.1
#=GS A0A0M0G211_9BACI/7-65     AC A0A0M0G211.1
#=GS R5KS95_9FIRM/8-72         AC R5KS95.1
#=GS A0A1F6RGK1_9BACT/3-66     AC A0A1F6RGK1.1
#=GS A0A0F2QNR7_9RHOB/15-78    AC A0A0F2QNR7.1
#=GS F2LV76_HIPMA/6-70         AC F2LV76.1
#=GS A0A1G6QNZ5_9BACL/4-66     AC A0A1G6QNZ5.1
#=GS A0A0A3IYL1_9BACI/12-74    AC A0A0A3IYL1.1
#=GS A0A1D7NJI3_9SPHN/7-70     AC A0A1D7NJI3.1
#=GS A0A268E2G1_9BACI/6-69     AC A0A268E2G1.1
#=GS A0A0F2JJ94_9FIRM/7-69     AC A0A0F2JJ94.1
#=GS V6SEA7_9FLAO/6-66         AC V6SEA7.1
#=GS A0A1I0S7S3_9BACT/8-72     AC A0A1I0S7S3.1
#=GS A0A1W1HI06_9DELT/11-73    AC A0A1W1HI06.1
#=GS A0A1I2Q7H9_9FIRM/17-81    AC A0A1I2Q7H9.1
#=GS A0A0Q7S2X6_9BACL/4-67     AC A0A0Q7S2X6.1
#=GS A0A1M7XYX2_9FIRM/12-72    AC A0A1M7XYX2.1
#=GS A0A1Z4H1J5_9CYAN/5-65     AC A0A1Z4H1J5.1
#=GS A0A1E3SSV2_9MYCO/3-65     AC A0A1E3SSV2.1
#=GS R6MRJ7_9FIRM/2-65         AC R6MRJ7.1
#=GS U4KJP9_ACHPJ/2-61         AC U4KJP9.1
#=GS A0A1I2MZ17_9BACL/13-75    AC A0A1I2MZ17.1
#=GS A0A285SEV9_9BACI/5-65     AC A0A285SEV9.1
#=GS M7NZJ1_9BACL/8-71         AC M7NZJ1.1
#=GS A0A1M7LK81_9BACT/9-73     AC A0A1M7LK81.1
#=GS Q81LM6_BACAN/4-68         AC Q81LM6.1
#=GS A0A1Y4NKP3_9FIRM/7-70     AC A0A1Y4NKP3.1
#=GS R9KMF6_9FIRM/7-70         AC R9KMF6.1
#=GS R6MYH2_9FIRM/8-71         AC R6MYH2.1
#=GS A0A1G9PJC4_9FIRM/4-73     AC A0A1G9PJC4.1
#=GS U2KG09_9FIRM/5-70         AC U2KG09.1
#=GS B8I1Z6_CLOCE/10-72        AC B8I1Z6.1
#=GS A0A0U3MMB4_9LACT/4-67     AC A0A0U3MMB4.1
#=GS L1QAX4_9CLOT/7-69         AC L1QAX4.1
#=GS A0A1G6S3U8_PEPNI/75-137   AC A0A1G6S3U8.1
#=GS R5GL41_9FIRM/4-66         AC R5GL41.1
#=GS A0A1G5JZY2_9CLOT/3-65     AC A0A1G5JZY2.1
#=GS A0A0F3IN87_9GAMM/20-86    AC A0A0F3IN87.1
#=GS A0A0G0VIJ8_9BACT/9-68     AC A0A0G0VIJ8.1
#=GS A0A0H4KG01_9BACI/5-66     AC A0A0H4KG01.1
#=GS R6GNW4_9CLOT/7-69         AC R6GNW4.1
#=GS E2SGH7_9FIRM/7-68         AC E2SGH7.1
#=GS A0A1Z4G995_9CYAN/19-79    AC A0A1Z4G995.1
#=GS D4L0U0_9FIRM/20-83        AC D4L0U0.1
#=GS A0A0H3GXK8_KLEPH/13-76    AC A0A0H3GXK8.1
#=GS A0A2C9T5J4_9MYCO/28-91    AC A0A2C9T5J4.1
#=GS A0A0F5VC72_9GAMM/8-64     AC A0A0F5VC72.1
#=GS A0A257TDY2_9BACT/9-68     AC A0A257TDY2.1
#=GS A0A1B7K2X6_9GAMM/13-75    AC A0A1B7K2X6.1
#=GS A0A0Q4SEL6_9FLAO/11-73    AC A0A0Q4SEL6.1
#=GS A0A0Q7GN69_9FLAO/8-72     AC A0A0Q7GN69.1
#=GS A0A1Q9K3S3_9FIRM/9-72     AC A0A1Q9K3S3.1
#=GS W6J6I9_9ENTR/3-70         AC W6J6I9.2
#=GS W6N9Y0_CLOTY/7-69         AC W6N9Y0.1
#=GS F7K2C6_9FIRM/9-74         AC F7K2C6.1
#=GS A0A1H5R380_9PSEU/24-79    AC A0A1H5R380.1
#=GS A3ZTQ0_9PLAN/29-90        AC A3ZTQ0.1
#=GS A0A1A9I3C2_9BACT/8-72     AC A0A1A9I3C2.1
#=GS R7A0W6_9CLOT/14-79        AC R7A0W6.1
#=GS K8W9L9_PRORD/12-73        AC K8W9L9.1
#=GS A0A086MKL5_9RHIZ/21-77    AC A0A086MKL5.1
#=GS A0A0F0CCT1_9CLOT/4-65     AC A0A0F0CCT1.1
#=GS A0A1I4GIA0_9FIRM/8-72     AC A0A1I4GIA0.1
#=GS A0A1S9I2B4_9CLOT/4-68     AC A0A1S9I2B4.1
#=GS A6GX68_FLAPJ/8-71         AC A6GX68.1
#=GS A0A1T5G870_9BACI/4-67     AC A0A1T5G870.1
#=GS C2CYY2_LACBR/28-90        AC C2CYY2.1
#=GS D2IZC3_9CAUD/5-65         AC D2IZC3.1
#=GS A0A0H0ZX45_9RHIZ/26-86    AC A0A0H0ZX45.1
#=GS A0A099VZ15_9LIST/9-67     AC A0A099VZ15.1
#=GS A0A1I2K8Q5_9CLOT/4-67     AC A0A1I2K8Q5.1
#=GS A0A1H8RU70_9FLAO/8-72     AC A0A1H8RU70.1
#=GS A0A1M5YQB0_9ACTN/11-72    AC A0A1M5YQB0.1
#=GS U2NLZ9_9CLOT/3-66         AC U2NLZ9.1
#=GS A0A1I6H073_9ALTE/9-75     AC A0A1I6H073.1
#=GS A0A094XIU1_BACAO/27-80    AC A0A094XIU1.1
#=GS N2ATG3_9FIRM/10-71        AC N2ATG3.1
#=GS A0A011RRX5_9LACT/14-81    AC A0A011RRX5.1
#=GS A0A1M7JV52_9RHOB/3-66     AC A0A1M7JV52.1
#=GS M1MVB0_9CORY/18-87        AC M1MVB0.1
#=GS N2A1K9_9FIRM/7-70         AC N2A1K9.1
#=GS A0A259LGN7_9RHIZ/6-70     AC A0A259LGN7.1
#=GS D6GPY5_FILAD/4-65         AC D6GPY5.1
#=GS G7WNI8_METH6/9-72         AC G7WNI8.1
#=GS A0A1I1YMT5_9BURK/5-60     AC A0A1I1YMT5.1
#=GS A0A085ZT49_9FLAO/8-72     AC A0A085ZT49.1
#=GS A0A1H8JLA4_9BACI/5-68     AC A0A1H8JLA4.1
#=GS A0A1G7PJA7_9RHOB/7-69     AC A0A1G7PJA7.1
#=GS R7RSQ2_9CLOT/9-71         AC R7RSQ2.1
#=GS R5L4C6_9CLOT/7-70         AC R5L4C6.1
#=GS A0A1D9FH22_9CLOT/13-80    AC A0A1D9FH22.1
#=GS A0A0B3W195_9FIRM/4-67     AC A0A0B3W195.1
#=GS A0A0J1G158_9FIRM/15-80    AC A0A0J1G158.1
#=GS R5AGU6_9FIRM/8-69         AC R5AGU6.1
#=GS A0A226HPQ9_9FLAO/11-73    AC A0A226HPQ9.1
#=GS A0A1Q2HNF4_9BACT/4-71     AC A0A1Q2HNF4.1
#=GS R6T6H4_9FIRM/5-69         AC R6T6H4.1
#=GS A0A0F6BJ17_GEOS0/9-70     AC A0A0F6BJ17.1
#=GS A0A090SU58_9VIBR/9-74     AC A0A090SU58.1
#=GS C6W376_DYAFD/13-77        AC C6W376.1
#=GS S6EJF1_AVIPA/5-67         AC S6EJF1.1
#=GS A0A147KD59_9ACTN/11-74    AC A0A147KD59.1
#=GS J2T011_9FLAO/51-112       AC J2T011.1
#=GS A0A1S9I1M5_9CLOT/7-69     AC A0A1S9I1M5.1
#=GS U2J2J1_9SPHI/11-74        AC U2J2J1.1
#=GS A0A1Y4R7Y5_9FIRM/4-67     AC A0A1Y4R7Y5.1
#=GS A0A176F7K9_9RHOB/8-68     AC A0A176F7K9.1
#=GS M7NLA3_9BACL/5-69         AC M7NLA3.1
#=GS A0A089HIA7_PAEDU/14-76    AC A0A089HIA7.1
#=GS A0A1U7MJ38_9FIRM/9-71     AC A0A1U7MJ38.1
#=GS A0A1F5JR81_9BACT/13-76    AC A0A1F5JR81.1
#=GS A0A0B5E0V1_9RHOB/3-66     AC A0A0B5E0V1.1
#=GS C2M3S7_CAPGI/9-71         AC C2M3S7.1
#=GS R6S2Z0_9BACE/9-72         AC R6S2Z0.1
#=GS A0A1S2LFF0_9BACI/6-67     AC A0A1S2LFF0.1
#=GS A0A1Y4IYC5_9FIRM/7-66     AC A0A1Y4IYC5.1
#=GS R9MPA6_9FIRM/13-74        AC R9MPA6.1
#=GS A0A1V3YVS3_9RHIZ/17-81    AC A0A1V3YVS3.1
#=GS A0A1S9PKS3_9SPHI/13-76    AC A0A1S9PKS3.1
#=GS A0A2G1ZRG2_9BACT/22-84    AC A0A2G1ZRG2.1
#=GS A0A226ITL3_9FLAO/11-75    AC A0A226ITL3.1
#=GS A0A1H4HLL4_9SPHI/14-78    AC A0A1H4HLL4.1
#=GS A0A0F4NKC0_9VIBR/3-67     AC A0A0F4NKC0.1
#=GS L0FTQ1_ECHVK/12-76        AC L0FTQ1.1
#=GS R6KL96_9BACE/9-72         AC R6KL96.1
#=GS C4IFW5_CLOBU/4-76         AC C4IFW5.1
#=GS A0A1M5A527_9CLOT/9-72     AC A0A1M5A527.1
#=GS A0A1I2ZFL8_9FIRM/5-68     AC A0A1I2ZFL8.1
#=GS A0A141E157_9VIRU/5-68     AC A0A141E157.1
#=GS A0A1I1YAR0_9FIRM/9-70     AC A0A1I1YAR0.1
#=GS Q5L9R0_BACFN/32-93        AC Q5L9R0.1
#=GS A0A173YNP9_CLOVE/7-67     AC A0A173YNP9.1
#=GS R6TBT3_9FIRM/14-78        AC R6TBT3.1
#=GS G8AHR9_AZOBR/5-67         AC G8AHR9.1
#=GS A0A1G7P3Y7_9SPHI/14-77    AC A0A1G7P3Y7.1
#=GS A0A269PJH6_9GAMM/4-66     AC A0A269PJH6.1
#=GS A0A1A9I6Y2_9BACT/22-82    AC A0A1A9I6Y2.1
#=GS D9QL33_BRESC/10-73        AC D9QL33.1
#=GS Q038R6_LACP3/6-67         AC Q038R6.1
#=GS A0A127VBZ1_9SPHI/13-75    AC A0A127VBZ1.1
#=GS R5Q2R3_9PROT/3-66         AC R5Q2R3.1
#=GS A0A160JHQ3_9PROT/5-71     AC A0A160JHQ3.1
#=GS T0SGE1_LACLC/7-68         AC T0SGE1.1
#=GS A0A143Z802_9LACT/4-67     AC A0A143Z802.1
#=GS A0A1G9AFC4_9FLAO/8-72     AC A0A1G9AFC4.1
#=GS A0A0Q7E984_9RHIZ/9-70     AC A0A0Q7E984.1
#=GS A0A1T4KLR7_9SPIO/11-76    AC A0A1T4KLR7.1
#=GS A0A0D6B965_RHOSU/11-73    AC A0A0D6B965.1
#=GS A0A143FQE3_9CAUD/17-80    AC A0A143FQE3.1
#=GS E2PZ29_STRC2/23-84        AC E2PZ29.1
#=GS U2B0P1_9CLOT/11-73        AC U2B0P1.1
#=GS A0A0Q6A1H5_9FLAO/4-67     AC A0A0Q6A1H5.1
#=GS U7MQ45_9CORY/17-85        AC U7MQ45.1
#=GS E2ELL8_9CAUD/14-77        AC E2ELL8.1
#=GS R6FRL1_9CLOT/7-68         AC R6FRL1.1
#=GS W7DF85_9LIST/4-66         AC W7DF85.1
#=GS A0A1M7DUA4_9FLAO/11-73    AC A0A1M7DUA4.1
#=GS S9S0A8_9RHOB/16-79        AC S9S0A8.1
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A0A094XIU1_BACAO/27-80               ...............................GNIIRALR......K.....V......A......D.....I...TQDELAY.............QL...K..IS................ERY..L.V.KIENG.........DA.-.T.MN.................F.Q.TY......................LL.I.R.N.Y.F....G..-...-..--......---.-----ke...............................................................
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A0A1I4ZHD0_9RHOB/6-68                ...............................GEKLRQVR......T.....N......R......K.....K...TLEELAT.............AI...G..SS................KAY..V.W.QLENK.........KN.A.K.PS.................A.E.LL......................LK.I.A.N.Y.L....G..E...S..PD......FFL.D----ds...............................................................
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A0A1G0PEN2_9BACT/10-69               ...............................GEVLRKLR......E.....V......N......K.....M...PLRKLAA.............QL...D..ID................QST..L.S.KIERN.........ER.-.K.AN.................A.E.LI......................DK.I.S.K.I.F....K..V...N..KK......DL-.-----qi...............................................................
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A0A1Q7T1F9_9BACT/4-67                ...............................GDRLRALR......E.....E......K......K.....L...SQGDIEK.............RT...G..LL................RCY..I.S.RVENG.........HT.-.V.PA.................I.E.TL......................EK.M.A.R.A.L....E..I...P..MY......QLF.-----yegde............................................................
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