GenomeNet

Database: Pfam
Entry: PF18838
LinkDB: PF18838
Original site: PF18838 
#=GF ID   LPD23
#=GF AC   PF18838.3
#=GF DE   Large polyvalent protein associated domain 23
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF SE   Iyer LM
#=GF GA   27.00 27.00;
#=GF TC   32.00 46.70;
#=GF NC   26.80 25.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   28559295
#=GF RT   Polyvalent Proteins, a Pervasive Theme in the Intergenomic
#=GF RT   Biological Conflicts of Bacteriophages and Conjugative Elements.
#=GF RA   Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;
#=GF RL   J Bacteriol. 2017; [Epub ahead of print]
#=GF DR   INTERPRO; IPR040696;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is an alpha-helical domain that is usually N-terminal to a
#=GF CC   metallopeptidase domain [1]. The domain is found in both in
#=GF CC   polyvalent proteins of conjugative elements and phages/prophages
#=GF CC   [1].
#=GF SQ   38
#=GS R6UCK3_9FIRM/85-142         AC R6UCK3.1
#=GS A0A0U1T6E4_9CAUD/2229-2286  AC A0A0U1T6E4.1
#=GS A0A1I2TL80_9RHIZ/120-177    AC A0A1I2TL80.1
#=GS R5KUU8_9FIRM/163-220        AC R5KUU8.1
#=GS N2IZY8_9PSED/1080-1137      AC N2IZY8.1
#=GS N2IZY8_9PSED/751-808        AC N2IZY8.1
#=GS A0A2K8I347_9CAUD/2217-2274  AC A0A2K8I347.1
#=GS A0A5C1E782_9RHOO/657-714    AC A0A5C1E782.1
#=GS U2SNH2_9FIRM/1119-1176      AC U2SNH2.1
#=GS A0A347VT82_9HELI/803-865    AC A0A347VT82.1
#=GS G9RUF2_9FIRM/60-120         AC G9RUF2.1
#=GS A0A368UA59_9GAMM/2094-2151  AC A0A368UA59.1
#=GS K4NZ44_9CAUD/668-725        AC K4NZ44.1
#=GS A0A0U1KXI5_9FIRM/567-627    AC A0A0U1KXI5.1
#=GS A0A3D8HXR9_9HELI/204-266    AC A0A3D8HXR9.1
#=GS A0A1G7CT62_9FLAO/4-66       AC A0A1G7CT62.1
#=GS A0A1I5PC38_9RHOB/125-182    AC A0A1I5PC38.1
#=GS A0A5Q0ELI1_9GAMM/630-687    AC A0A5Q0ELI1.1
#=GS J6UE11_9RHOB/115-173        AC J6UE11.1
#=GS A1TPS0_ACIAC/1527-1584      AC A1TPS0.1
#=GS A0A368UA59_9GAMM/1150-1207  AC A0A368UA59.1
#=GS A6KYZ4_BACV8/543-604        AC A6KYZ4.1
#=GS A0A5Q0EGR4_9GAMM/1056-1113  AC A0A5Q0EGR4.1
#=GS A6L6L1_BACV8/470-531        AC A6L6L1.1
#=GS G9RUD9_9FIRM/91-150         AC G9RUD9.1
#=GS A0A1I3LHZ4_9RHOB/131-188    AC A0A1I3LHZ4.1
#=GS N2IZY8_9PSED/1519-1576      AC N2IZY8.1
#=GS A0A2M8RXZ8_9PAST/1160-1217  AC A0A2M8RXZ8.1
#=GS A0A1N6XKH7_9GAMM/296-353    AC A0A1N6XKH7.1
#=GS Q5QF61_9CAUD/39-96          AC Q5QF61.1
#=GS R5YQ00_9PROT/609-666        AC R5YQ00.1
#=GS A0A2D3WMN3_9PROT/1313-1370  AC A0A2D3WMN3.1
#=GS A0A327JR81_9RHIZ/139-197    AC A0A327JR81.1
#=GS A0A323URW8_9RHOO/738-795    AC A0A323URW8.1
#=GS A0A5D6WDM4_9FIRM/1253-1310  AC A0A5D6WDM4.1
#=GS N2IZY8_9PSED/1940-1997      AC N2IZY8.1
#=GS G9RUE2_9FIRM/149-209        AC G9RUE2.1
#=GS A0A166HBT0_9GAMM/2784-2841  AC A0A166HBT0.1
R6UCK3_9FIRM/85-142                    .............HSLAGQYS..Q.....TAKLNSLSGAVRMNENGTP...MDTIRARTGWWLG.KDGK.WRYEIDDSALSF-d....
A0A0U1T6E4_9CAUD/2229-2286             .............YSFAGRNA..V.....GANLHALSTAQQRIAIGEN...AEAVRRDTGWHRS.ADGK.WRFEISDHQASI-a....
A0A1I2TL80_9RHIZ/120-177               ............r-MFGGWNA..E.....TADHAALSKAQNLKATGAD...RQAIWDQTGWFQA.PDNY.WRFEIPDDLATL-g....
R5KUU8_9FIRM/163-220                   .............YSYGGRNS..N.....NVDLRELQRTNEMEKEGES...FEEIFKKTGWFRG.IDNI.WKYEIDDSKMTFN.....
N2IZY8_9PSED/1080-1137                 ............f-AFAGEEA..V.....SAPLELLAQAKVMHSQAAD...SADIWATTGWSIG.MDGR.WRFEIDDSTATLH.....
N2IZY8_9PSED/751-808                   ............f-AFGGELG..A.....DLNLESLDVAQIMLAQGDD...SETIRQATGWFTG.IDGK.WRFEIDDSQAEL-v....
A0A2K8I347_9CAUD/2217-2274             .............YSFAGRNA..V.....GANLHALSTAQQRIAIGEN...AEAVRRDTGWHRS.ADGK.WRFEISDHQASI-a....
A0A5C1E782_9RHOO/657-714               .............FSFAGRKA..Q.....GADLHALNTAQQRLARGED...AEAVRQATGWHRG.ADGK.WRFEISDHQASI-a....
U2SNH2_9FIRM/1119-1176                 .............YSFGGENA..R.....RADLDALDRAKEMERQGVA...METIFRETGWYTG.ADGK.WRFEIDDSGMEY-s....
A0A347VT82_9HELI/803-865               .............YIFAGEKA..LqqkgfNTQIKNLKTAKDLESKGES...AESIWQKTGWYKD.KDSK.WKFEIDSSKGKLK.....
G9RUF2_9FIRM/60-120                    ..........gsv--AGEKYSfvR.....ATDAEQIARAQELEAQGEN...AKTIWSETHLTRD.GGGA.WVQEINDHDAKP-r....
A0A368UA59_9GAMM/2094-2151             ............l-SFAGESA..R.....TADRLTLAYAQKALAAGMA...PNLVREQTGWHQG.VDGR.FRFEINDSKARL-l....
K4NZ44_9CAUD/668-725                   ............d-QFAGQTA..W.....SADMPSLADAEQRIADGDN...AEQVRRETGWSQG.ADGK.WRFEIDDSQAQF-a....
A0A0U1KXI5_9FIRM/567-627               .............HQYAGTQA..L.....TADRLNLQEAQKLEAAGEDvgaAGSIRQKTGWHKG.QDNK.WRFEIDDSKAKM-v....
A0A3D8HXR9_9HELI/204-266               ............q-ILAGEKA..LlsqtyAPQKAKLEHAKALQIEGKS...AAEIWENTGWYQD.IDKN.WKFEINPQGG---ele..
A0A1G7CT62_9FLAO/4-66                  ........hiige--KGARNLpdA.....DKILRDKDEAEDMLRGGYD...PEIVRRQTGWYEG.GDGK.MRYELQDKNFHLN.....
A0A1I5PC38_9RHOB/125-182               ............n-IFAGPGA..A.....NADRSALSRAEQMEQAGVD...RDHIWRSTGWGRG.VDDQ.WRFEIDDSAARV-g....
A0A5Q0ELI1_9GAMM/630-687               ............g-SFAGRNA..R.....TANADRLARAEQMETDGAD...ARTIWRETGWYKD.VDGK.WRFWINDNAASI-k....
J6UE11_9RHOB/115-173                   ............g-VFGGPGA..K.....TADHAALAEAKRLAAGGAP...MPEVYKATGWYED.PATKaWRFFIPDDAMTV-t....
A1TPS0_ACIAC/1527-1584                 .............FSFAGRNA..R.....SADLGELERAEAMARSGMS...SAVIQQETGWHRG.VDGR.WRFEISDDTAEFR.....
A0A368UA59_9GAMM/1150-1207             .............FSFAGVGA..Q.....TADIHQLDYAKKALKDGLS...AEQVRQQTGWFQG.DDKK.WRFEIDDSQARY-l....
A6KYZ4_BACV8/543-604                   gekgasrldrseg--------..A.....SLRLENLAVAREMEKSGKD...AGTIKAATGWERG.ADSK.WRYETAD------feyhp
A0A5Q0EGR4_9GAMM/1056-1113             ............g-SFAGPNA..K.....TANAQTLDNAQQMLADGAD...GPTIWKATGWYQD.EDGM.WRSEIDDNAAVF-n....
A6L6L1_BACV8/470-531                   gekgasrldrseg--------..A.....SLRLENLAVAREMEKSGKD...AGTIKAATGWERG.ADSK.WRYETAD------feyhp
G9RUD9_9FIRM/91-150                    .............YSFVGEKAnlN.....RTERAALETAKGMEQDGET...NEDIRRQTGWFRG.ADGK.WRMEVDDSGAVY-y....
A0A1I3LHZ4_9RHOB/131-188               ............g-IFAGVKA..A.....NAPTDMLRRAEEMTAAGAN...RDDVWRETGWFQG.VDGK.WRWEIEDSDAFL-e....
N2IZY8_9PSED/1519-1576                 .............FSFAGPRA..L.....SAERSSLLKAKERHASGES...AQAIRQVTGWFLG.ADDK.WRFEIDDSKANA-r....
A0A2M8RXZ8_9PAST/1160-1217             .............YSFAGEKA..K.....TADHSLLEQAKADIAKGVN...PEIVRQETGWFRG.VDGK.WRFEISDNEVSF-k....
A0A1N6XKH7_9GAMM/296-353               .............YQYGSTHA..E.....AANTEQLSIAKSLKQAGAD...PESIRQMTGWHQW.IDGR.WRFEIDDSRASLK.....
Q5QF61_9CAUD/39-96                     .............YSFAGRNA..V.....GANLHALSTAQQRIAMGEN...AEAVRRDTGWHRG.TDGK.WRFEISDHQASI-a....
R5YQ00_9PROT/609-666                   .............FQFGGVEA..K.....FADFKKLAEAYKLEQQDYS...PRLIWSRTGWYRG.GDGR.WRFEINDSGAKLK.....
A0A2D3WMN3_9PROT/1313-1370             ...........lt--FAGEKA..I.....KADVAKLDDAMKLADSGAK...ESDIWRSTGWFKG.DDGK.WRFEVDDSGAKM-l....
A0A327JR81_9RHIZ/139-197               ............g-VFGGRLA..Q.....TADHAALARAEAMRAAGES...RKAIWRETGWFTDpADGR.WKFYIPDEAMTV-t....
A0A323URW8_9RHOO/738-795               .............FSFAGRDA..E.....TADLHGLGNAQRRIAAGEN...PEAVRQATGWHRG.ADGM.WRFEISDEQARL-a....
A0A5D6WDM4_9FIRM/1253-1310             ............n-QMAGVNA..Y.....GAAKGSLLRAKSMDAKKQS...PDKIFDKTGWLKG.ADGK.WRFEIPDN-----ldnih
N2IZY8_9PSED/1940-1997                 .............YSFAGVNA..H.....TAPLLALADARLRLELGEK...AESVWQATGWLHG.SDGK.WRFEIDDSAASV-l....
G9RUE2_9FIRM/149-209                   ..........gsv--AGEKYSfvR.....ATDAEQIARAQELEAQGEN...AKTIWSETHLTRD.GGGA.WVQEINDRGVKP-r....
A0A166HBT0_9GAMM/2784-2841             .............YSFGGELS..L.....NANMEQLNRAKEMHVDGES...RTAIWHETGWFKD.VDDH.WKYEIDDSGAGI-h....
#=GC seq_cons                          ..............pFAGppA..t.....sAchpsLspApphtspGts...scsIhppTGWacG.sDGK.WRFEIsDstAph.h....
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