GenomeNet

Database: Pfam
Entry: PF18853
LinkDB: PF18853
Original site: PF18853 
#=GF ID   LPD37
#=GF AC   PF18853.3
#=GF DE   Large polyvalent protein associated domain 37
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF SE   Iyer LM
#=GF GA   27.00 27.00;
#=GF TC   245.70 244.70;
#=GF NC   26.20 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   28559295
#=GF RT   Polyvalent Proteins, a Pervasive Theme in the Intergenomic
#=GF RT   Biological Conflicts of Bacteriophages and Conjugative Elements.
#=GF RA   Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;
#=GF RL   J Bacteriol. 2017; [Epub ahead of print]
#=GF DR   INTERPRO; IPR041196;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is and alpha and beta fold domain that is found in
#=GF CC   polyvalent proteins that are likely to be phage/prophage-derived
#=GF CC   [1].
#=GF SQ   14
#=GS H2DE57_9CAUD/3367-3608      AC H2DE57.1
#=GS H8GN40_METAL/80-313         AC H8GN40.1
#=GS A0A345BLY4_9CAUD/3460-3701  AC A0A345BLY4.1
#=GS A0A2G3JZJ7_9BURK/381-657    AC A0A2G3JZJ7.1
#=GS A0A1T4XZQ6_9BACT/1207-1462  AC A0A1T4XZQ6.1
#=GS A0A1C9VHP3_9BURK/779-1029   AC A0A1C9VHP3.1
#=GS A0A1T4Z3Z3_9BACT/803-1062   AC A0A1T4Z3Z3.1
#=GS A0A1Y6CWK4_9GAMM/4118-4354  AC A0A1Y6CWK4.1
#=GS A0A2G3JY63_9BURK/143-393    AC A0A2G3JY63.1
#=GS A0A0S4K143_9BURK/3936-4245  AC A0A0S4K143.1
#=GS A0A106BIY4_THIDE/812-1082   AC A0A106BIY4.1
#=GS A0A127CHD0_9RHIZ/3806-4048  AC A0A127CHD0.1
#=GS A0A1H7NRT2_9PROT/192-432    AC A0A1H7NRT2.1
#=GS A0A2G3K2Q5_9BURK/3009-3258  AC A0A2G3K2Q5.1
H2DE57_9CAUD/3367-3608                 .d-AMAELAAHDEMFAYPrATGQRTLQGVFDTVMPDVKIRWETPKLDD-N......SNETEVTHIRGVT-GRGRDINIY.QTPE-EVWFDVSNVN...EG.EGGAGIYQAVAEYALNTGRKFVGDPDGLSDIALRRRTEAMLSSALKHGTTDHLEPHERQLKGDKALGV.......PALRWKEGDFAFNIRSLIDTSLANIKAAVP....EIDRARYDFESGHYR.TG..................................................DGKPLLAETIERWV-.......................GHPKLRAARAGSATVKRSILLNSLSRT-e.....................
H8GN40_METAL/80-313                    ..EVLNELAEVDEFFRFP.VSPKTTLDGVMKDIAPDFEFVGEDTREDE--......RSESGADRRFVFKTDKGKPFYVY.ERGD-EIWIDVSRLS...TG.EGGAAIYHALGNYAHNADKVFVGDPAGLSDDAVIRRTANMLSLALRLGTTDFMEPSIEQRRGIPEIGV.......VPLKWQ-GSDVDKTQSLIQTFLANLQKSIS....RIIRI-FSMTSEK--.DS..................................................LYDPLTDNPWT----.......................GPSSISTKRSMELDEQREQVRQRLVA--ah....................
A0A345BLY4_9CAUD/3460-3701             .d-ALAELAAHDEMFAYPrATGLRSLQGVFDTVMPDVKIRWETPKLDD-N......SNETEVTHIRGVT-GRGRDINIY.QTAD-EVWFDVSNVN...EG.EGGAGIYQAVAEYALNTGRKFVGDPDGLSDIALRRRTEAMLSSALKHGTTDHLEPHERQLNGDKALGV.......PPLRWKEGDFAFNIRSLIDTSLANIKAAVP....EIDRARYDFDSGTYR.TG..................................................KGEPILAETLRSWS-.......................ERGKVRAARAGVSTLRRSILLNTLART-e.....................
A0A2G3JZJ7_9BURK/381-657               .m-AWKLLAQADELFRFP.RPQSFGLADIAAEIDPGLSVVVDQKAYSKAE......RDEQKIAHVWKMTMADRKEAWII.ENQSGEVWIDASSLA...KGvSGGGKLYAAVASYAAANGKVFIGDPAGLSEAALVRRTEQMLSSALKEGMTQHLMPHERQMAPDSYQANakindaiRPITWVPGDDAHNLLELLKTSYHNVRQLVPdvakELNHVSYSFEKSRF-.ER..................................................DGKPVDDEYFNDLAAdsarelrrhg..faelvtrstgnSGRTQDRSVLGSATLKRTVITRTLLREA......................
A0A1T4XZQ6_9BACT/1207-1462             ..NVHRTLAESEEAFQFGkNKPTTQGDSRNSYWREALDDVADAYSQKDHAiniiseHESFPGGYAFNVEAKNGSAFVVI.NEERKTVHINAAGLNsnaEKsGGGSQVYQMVQTFAHNNGFKFIPDGT-VSPIAKKRRISQMISSALRHKSTDHLNGLMDLDDGSKT---.......EVPGWRKGAHDYNLGLLLRAEHDYVMAEARqravDLSHLTHDPTTNNIIdGH..................................................TGTPVTQRTLQSLV-.......................DRLEPGASGVGASTLLRALVTGSALQG-g.....................
A0A1C9VHP3_9BURK/779-1029              tt--LLELGRGEGLYQLP.RSQATDIAQMAAEKDLEVR-PVDRNAADSTEwmlantTPEAEGTESWVVSTSDGRLGTIT.RDGN-EVYINVSAVG...EG.GGGSAIYDLVANYALNNGLVFIGDPNGVSEAAMRRRLENMLSSAVKYGTTDHIAPHPDQLLGNTVQGI.......APLKWTPGDTLGNIRSLVEASLATTEAAAP...lTTSEVQFDVDTQQFR.QP..................................................DGTPADAAVVRSVLS......................fEPRVRGTGAPGQTTVQRAALYRALLQG-p.....................
A0A1T4Z3Z3_9BACT/803-1062              .s-VHRSIAESQEAFQLGkSKPDTQGYAKENDWRDSLEDLAKAYSVVESPlnvgedYPSHPDGYAFNLHTKKGSAFVVI.DPAMGTVHINSAGLDsnqEKfGGGSQVYQMVQTFAKNNGLTFKPDHT-VSPIAQKRRISQMASSALRHGSTAHLDGLATYTDGETGEIK......tEVPGWKPGDNDHNLALLLKMEHAYVMQEAQargiDLGHLTHDPATHNIIdGH..................................................TGTSITEGTLRSLV-.......................DRFKSADSGVGETTLLRALVTGSALQR-g.....................
A0A1Y6CWK4_9GAMM/4118-4354             ..EVWKLLARHSEAFQYS.KPQSGDMADIAAEIDPGMEVTDLGG------......SSTGENRHLWFVQMPNGDPATVR.EDRQGRVIVNAASLT...EG.GGGSALYALVSAYAHNNGKVFIGDPEGLSDEALFRRTENMLSSALKYGTTRHLRPHPRQEGFWKRWGL.......A---WKDGDDAHNLETLLLASYHAVTEAFP....EIKDVVYDFDARAFRnTR..................................................DGQFVGDPDFKLAAA.......................QSRGGRAAKAGSATLKRTVITNTLVRG-a.....................
A0A2G3JY63_9BURK/143-393               .m-AWKLLAQADELFRFP.RPQSFDLADIAAEIDPGLSVVVDQKAYSKAE......RDEQKIAQVWKMTMADRKEAWII.ENQTGEVWIDASSLA...KGlSGGGKLYAAVASYAAANGKVFIGDPAGLSEAALVRRTEQMLSSALKEGMTQHLMPHERQMAPDSYQPNakindaiRPITWVPGDDAHNLLELLKTSYHNVRQLVPdvakELNHVSYSFEKGRF-.ET..................................................DGEPVDDKYFQELAG.......................R---------------------------aalelqrhgfpglvsgrasdsg
A0A0S4K143_9BURK/3936-4245             ..NIFSQIATDDAAFRMP.DSNAKTLAGILADMAPTLS-VDEFVAEGDLE......DAAAPVDRAWHITSPTGEQASVYrNNRNKEIWLDISNWK...EG.RTGSGVYQAVATLAHNTGHVFIGDPAGLSDKALYRRTEHMISSALRHGTTKHLAPHARQVKATGTAGGa....dvRPIAWRDGDDAHNLQEMLVSSYTNILHLFP....EIADVTYNFARARFErAPvrasagalradqsdlgewsdeqglgpayggstsgrgtdradegardvgrvDAVPFTNEDFVTAAEsvrna............ydvffpTARGMYTPPIGMSDIKRAVLTQSVLQEA......................
A0A106BIY4_THIDE/812-1082              ..KAWKMLAGNEAIFQNP.MPDSFDMEGAAREIDPGMSAVADKPDLDE--......-QKTGITKKWYVTMPDGTHAYVM.ENKQGEVWLDASRLE...EGaSGGAKLYLLVGSYAEGNGKVFIGDPAGLSDVALIRRTENMLSLALRFGKTSFMRPHEYQMNPDAKQGTvla.gvvKPLEWVEGNDANNIEELIRTSYANTVKLVA....EVKDVTFNFDKQRF-.EQ..................................................DGVEFTKDGFKRLVDglpgalrkrglskivttrnpggkGGAAEDFAPIGIATLKRAAVTNTLARE-t.....................
A0A127CHD0_9RHIZ/3806-4048             .q-ALAELAAVDELFQNPkATGKRTLKGVFEAIDPTVRFIGDMERSDE--......EEASGAEQRFLLRTAKGRDFYIF.QTPD-DVWTDISQLH...EG.GSGARIYQAIAEYAFNTDRTFIGDPAGLTDIALRRRNEAMLSSALKHGTTQHLEPHERQLKGEKAIGV.......PPLHWKNGDDLGNIRSLIDVSLGSIKSKFP....EIDDARYDFETRTFR.DS..................................................EGEPLSDEVLARWAS.......................SLRGVREARAGSATLKRSILLNTLSRQ-s.....................
A0A1H7NRT2_9PROT/192-432               .d-FLVELADVDELFRHA.ISHKTSLKGVFSEVYPDAVYVGDGTREDE--......RDESGADHRYVFKLPNGKQFYVY.ERDNGEVFIDVSHFS...TG.ERGQAVYAAVANWAYNTKRKFIGDPAGLTADSLIRRTSNMLSSALRFGTVKHLEAAPQQIAGDPKNGV.......PPLDWS-GDDVAKTRALIHTFIETLHNKFP....EITSYRYDFANRQFT.DR..................................................LGRPVGLDRFTHAE-.......................ATGLGGSARAGKASMRRGILIQSLISS-e.....................
A0A2G3K2Q5_9BURK/3009-3258             .m-AWKLLAQADELFRFP.RPQSFDLADIAAEIDPGLSVVVDQKAYSKAE......RDEQKIAQVWKMTMADRKEAWII.ENQTGEVWIDASSLT...KGiSGGGKLYAAVASYAAANGKVFIGDPAGLSEAALVRRTEQMLSSALKEGMTQHLMPHARQMDPDSYQPNakindaiRPITWVPGDDAHNLLELLKTSYHNVRQLVPdvakELNHVSYSFEKGRF-.ET..................................................DGEPVDDKYFQELAG.......................R---------------------------aalelqrhgfpglvsgrasds.
#=GC seq_cons                          ...shppLApsDEhFpaP.tstspsLtulhs-lcPslphls-tht.s-........pscstsschahlphscG+phhlh.cststEVWlDsSsLs...EG.uGGutlYtAVAsYAtNsG+sFIGDPsGLS-hALhRRTEpMLSSAL+aGoTpHLpPHtcQhsu-st.Gs.......tPlpWp.GDDsaNlppLlcoShsslpptsP....ElsclpYsF-sppF..sp..................................................-GpPlsscshpphs........................sttt.tsutsGtuTlpRullhpoLhpt.s.....................
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