GenomeNet

Database: Pfam
Entry: PKD
LinkDB: PKD
Original site: PKD 
#=GF ID   PKD
#=GF AC   PF00801.22
#=GF DE   PKD domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   [1]
#=GF GA   23.50 23.50;
#=GF TC   23.50 23.50;
#=GF NC   23.40 23.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   PKD_domain
#=GF CL   CL0159
#=GF RN   [1]
#=GF RM   7736581
#=GF RT   Polycystic kidney disease: the complete structure of the PKD1
#=GF RT   gene and its protein. 
#=GF RA   The International Polycystic Kidney Disease Consortium; 
#=GF RL   Cell. 1995;81:289-298.
#=GF RN   [2]
#=GF RM   9889186
#=GF RT   The structure of a PKD domain from polycystin-1: implications
#=GF RT   for polycystic kidney disease. 
#=GF RA   Bycroft M, Bateman A, Clarke J, Hamill SJ, Sandford R, Thomas
#=GF RA   RL, Chothia C; 
#=GF RL   EMBO J 1999;18:297-305.
#=GF DR   INTERPRO; IPR000601;
#=GF DR   SCOP; 1b4r; fa;
#=GF DR   SMART; PKD;
#=GF DR   HOMSTRAD; PKD;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain was first identified in the Polycystic kidney
#=GF CC   disease protein PKD1. This domain has been predicted to contain
#=GF CC   an Ig-like fold [1].
#=GF SQ   6697
#=GS A0A3Q3AZX5_KRYMA/212-288    AC A0A3Q3AZX5.1
#=GS A0A452EV73_CAPHI/1551-1620  AC A0A452EV73.1
#=GS A0A452J302_9SAUR/1734-1805  AC A0A452J302.1
#=GS H2NPT1_PONAB/1385-1456      AC H2NPT1.2
#=GS Q2FPC4_METHJ/1029-1094      AC Q2FPC4.1
#=GS A0A1V4KSM9_PATFA/1840-1909  AC A0A1V4KSM9.1
#=GS A0A4X2KWQ0_VOMUR/1386-1451  AC A0A4X2KWQ0.1
#=GS F6UM55_HORSE/1810-1876      AC F6UM55.3
#=GS A0A1U7QY57_MESAU/1548-1617  AC A0A1U7QY57.1
#=GS A0A5A9PYV7_9TELE/893-962    AC A0A5A9PYV7.1
#=GS A0A212CYZ4_CEREH/781-850    AC A0A212CYZ4.1
#=GS A0A6J3Q087_TURTR/980-1072   AC A0A6J3Q087.1
#=GS A0A1S3Q6A4_SALSA/946-1009   AC A0A1S3Q6A4.1
#=GS A0A2K6DWP2_MACNE/1980-2055  AC A0A2K6DWP2.1
#=GS Y1468_METJA/728-799         AC Q58863.1
#=GS A0A2Y9FVK0_TRIMA/1560-1629  AC A0A2Y9FVK0.1
#=GS A0A3Q2I0F1_HORSE/803-880    AC A0A3Q2I0F1.1
#=GS A0A160T0J7_9CHLR/167-233    AC A0A160T0J7.2
#=GS A0A452EV73_CAPHI/1384-1454  AC A0A452EV73.1
#=GS H9GEX9_ANOCA/1344-1419      AC H9GEX9.1
#=GS A0A512D8S9_9CELL/173-252    AC A0A512D8S9.1
#=GS A0A553GSE8_9BACT/533-598    AC A0A553GSE8.1
#=GS U5VZK6_9ACTN/452-527        AC U5VZK6.1
#=GS A0A673ALL3_9TELE/339-417    AC A0A673ALL3.1
#=GS A0A2K6GHA3_PROCO/529-600    AC A0A2K6GHA3.1
#=GS A0A2I3SQ13_PANTR/561-638    AC A0A2I3SQ13.1
#=GS A0A091K0S2_EGRGA/1583-1652  AC A0A091K0S2.1
#=GS W5MXP1_LEPOC/1129-1213      AC W5MXP1.1
#=GS A0A5A9PJ94_9TELE/1643-1718  AC A0A5A9PJ94.1
#=GS A0A093IN08_FULGA/194-270    AC A0A093IN08.1
#=GS A0A3B3IFV1_ORYLA/375-441    AC A0A3B3IFV1.1
#=GS A0A091HKC7_CALAN/864-933    AC A0A091HKC7.1
#=GS A0A3M6UQY4_9CNID/138-205    AC A0A3M6UQY4.1
#=GS F7F1Y7_MACMU/509-578        AC F7F1Y7.3
#=GS A0A663EIV1_AQUCH/588-669    AC A0A663EIV1.1
#=GS E4TV59_MARTH/933-1003       AC E4TV59.1
#=GS A0A5N5MLK8_PANHP/69-143     AC A0A5N5MLK8.1
#=GS A0A264Y6B3_9BACT/448-514    AC A0A264Y6B3.1
#=GS A0A6J3PZL9_TURTR/1840-1911  AC A0A6J3PZL9.1
#=GS A0A437DLF9_ORYJA/1679-1749  AC A0A437DLF9.1
#=GS A0A452EV73_CAPHI/1470-1536  AC A0A452EV73.1
#=GS A0A091VDT0_OPIHO/596-672    AC A0A091VDT0.1
#=GS A0A672YNE3_9TELE/1160-1229  AC A0A672YNE3.1
#=GS G3QVU1_GORGO/275-346        AC G3QVU1.2
#=GS A0A673AQA2_9TELE/190-265    AC A0A673AQA2.1
#=GS A0A411YHQ0_9ACTN/1585-1657  AC A0A411YHQ0.1
#=GS A0A1D5P8Y1_CHICK/1954-2027  AC A0A1D5P8Y1.1
#=GS A0A4X2KQ46_VOMUR/1135-1200  AC A0A4X2KQ46.1
#=GS H3B277_LATCH/1248-1307      AC H3B277.1
#=GS A0A5F9DGW0_RABIT/1791-1859  AC A0A5F9DGW0.1
#=GS A0A1S3WHS1_ERIEU/825-916    AC A0A1S3WHS1.1
#=GS A0A1B0GRC4_MOUSE/803-880    AC A0A1B0GRC4.1
#=GS A0A4Q7MBC6_9BACT/31-97      AC A0A4Q7MBC6.1
#=GS A0A670JM92_PODMU/1732-1799  AC A0A670JM92.1
#=GS A0A3Q7R4S8_VULVU/1419-1484  AC A0A3Q7R4S8.1
#=GS A0A5C6N560_9TELE/214-287    AC A0A5C6N560.1
#=GS A0A1S3A740_ERIEU/797-874    AC A0A1S3A740.1
#=GS A0A3P4M1F7_GULGU/1359-1428  AC A0A3P4M1F7.1
#=GS A0A099YZU4_TINGU/1226-1294  AC A0A099YZU4.1
#=GS A0A210R4X5_MIZYE/2076-2145  AC A0A210R4X5.1
#=GS A0A093PUP2_PHACA/1553-1625  AC A0A093PUP2.1
#=GS SORC3_HUMAN/826-904         AC Q9UPU3.2
#=GS A0A671UXW9_SPAAU/212-284    AC A0A671UXW9.1
#=GS G1N2X4_MELGA/1930-2003      AC G1N2X4.2
#=GS A0A2Y9PCT0_DELLE/249-313    AC A0A2Y9PCT0.1
#=GS A0A2K5K5V5_COLAP/1469-1538  AC A0A2K5K5V5.1
#=GS A0A3Q2KY63_HORSE/201-270    AC A0A3Q2KY63.1
#=GS A0A1S3QG50_SALSA/660-716    AC A0A1S3QG50.1
#=GS A0A2U9BPI8_SCOMX/1640-1709  AC A0A2U9BPI8.1
#=GS G3WU86_SARHA/1227-1297      AC G3WU86.1
#=GS A0A172TUU4_9BACT/917-988    AC A0A172TUU4.1
#=GS A0A3P8T1H6_AMPPE/1104-1195  AC A0A3P8T1H6.1
#=GS H3D991_TETNG/1322-1393      AC H3D991.1
#=GS G1N2X4_MELGA/1845-1914      AC G1N2X4.2
#=GS H0YX20_TAEGU/254-320        AC H0YX20.2
#=GS W5Q7Y6_SHEEP/204-274        AC W5Q7Y6.1
#=GS G3QVU1_GORGO/1369-1440      AC G3QVU1.2
#=GS F6UM55_HORSE/1635-1708      AC F6UM55.3
#=GS A0A402E5K9_9SAUR/862-937    AC A0A402E5K9.1
#=GS A0A672H7N8_SALFA/1610-1679  AC A0A672H7N8.1
#=GS R6P064_9FIRM/112-179        AC R6P064.1
#=GS H3DCH3_TETNG/997-1065       AC H3DCH3.1
#=GS A0A674GW58_TAEGU/207-283    AC A0A674GW58.1
#=GS A0A3M6U431_9CNID/1696-1761  AC A0A3M6U431.1
#=GS A0A2K6CUF3_MACNE/561-638    AC A0A2K6CUF3.1
#=GS A0A2K5L9R4_CERAT/561-638    AC A0A2K5L9R4.1
#=GS A0A096NUA0_PAPAN/267-343    AC A0A096NUA0.2
#=GS G1T4A6_RABIT/1422-1493      AC G1T4A6.3
#=GS A0A6A5FM08_PERFL/1478-1542  AC A0A6A5FM08.1
#=GS A0A091TGE2_PHALP/562-638    AC A0A091TGE2.1
#=GS A0A670JM92_PODMU/1137-1208  AC A0A670JM92.1
#=GS A0A2K6SR68_SAIBB/270-321    AC A0A2K6SR68.1
#=GS A0A2I0TKI2_LIMLA/1215-1288  AC A0A2I0TKI2.1
#=GS A0A4W5NTH4_9TELE/871-948    AC A0A4W5NTH4.1
#=GS A0A673TX47_SURSU/1900-1975  AC A0A673TX47.1
#=GS A0A3M6U7M2_9CNID/263-328    AC A0A3M6U7M2.1
#=GS A0A4W3IKU7_CALMI/176-221    AC A0A4W3IKU7.1
#=GS A0A4S2LEG8_OPIFE/524-592    AC A0A4S2LEG8.1
#=GS A0A3P8VIT6_CYNSE/1093-1184  AC A0A3P8VIT6.1
#=GS A0A091MEJ1_CARIC/2009-2078  AC A0A091MEJ1.1
#=GS A0A1Q6A582_9SPHI/414-485    AC A0A1Q6A582.1
#=GS A0A099ZNT3_TINGU/231-297    AC A0A099ZNT3.1
#=GS A0A091LF84_9GRUI/1577-1646  AC A0A091LF84.1
#=GS A0A663EIF4_AQUCH/734-810    AC A0A663EIF4.1
#=GS A0A2U3ZIK0_ODORO/1975-2050  AC A0A2U3ZIK0.1
#=GS A0A1A6HQ82_NEOLE/1665-1734  AC A0A1A6HQ82.1
#=GS A0A671VIY3_SPAAU/816-891    AC A0A671VIY3.1
#=GS F5X2P3_STRPX/697-765        AC F5X2P3.1
#=GS A0A5F9CCK4_RABIT/1055-1147  AC A0A5F9CCK4.1
#=GS A0A6C2USN9_9BACT/699-761    AC A0A6C2USN9.1
#=GS A0A5J5MSK5_MUNRE/1217-1287  AC A0A5J5MSK5.1
#=GS A0A218V9C6_9PASE/627-704    AC A0A218V9C6.1
#=GS A0A1S3MGU5_SALSA/213-288    AC A0A1S3MGU5.1
#=GS A0A3Q3F3Q8_9LABR/1351-1424  AC A0A3Q3F3Q8.1
#=GS A0A5F9CCK4_RABIT/1248-1316  AC A0A5F9CCK4.1
#=GS A0A430QMN3_SCHBO/481-542    AC A0A430QMN3.1
#=GS A0A2K6FK75_PROCO/257-321    AC A0A2K6FK75.1
#=GS A0A485PV64_LYNPA/1636-1708  AC A0A485PV64.1
#=GS A0A2U3ZIK0_ODORO/1024-1116  AC A0A2U3ZIK0.1
#=GS A0A2K6TRN5_SAIBB/1143-1212  AC A0A2K6TRN5.1
#=GS A0A2P7TD63_9SPHI/510-577    AC A0A2P7TD63.1
#=GS A0A1B1FXN5_9BACT/60-104     AC A0A1B1FXN5.1
#=GS A0A6I8QJD5_XENTR/1065-1133  AC A0A6I8QJD5.1
#=GS A0A670JK59_PODMU/1270-1342  AC A0A670JK59.1
#=GS A0A091WH70_OPIHO/597-673    AC A0A091WH70.1
#=GS A0A0A0MRC2_HUMAN/561-638    AC A0A0A0MRC2.1
#=GS A0A2K6PUS3_RHIRO/1806-1875  AC A0A2K6PUS3.1
#=GS A0A452FP96_CAPHI/247-318    AC A0A452FP96.1
#=GS A0A6J3PZR6_TURTR/1637-1709  AC A0A6J3PZR6.1
#=GS A0A5C8J8S2_9BACT/362-445    AC A0A5C8J8S2.1
#=GS A0A6I8N3V4_ORNAN/1306-1375  AC A0A6I8N3V4.1
#=GS A0A2Y9N3A6_DELLE/252-327    AC A0A2Y9N3A6.1
#=GS A0A3P4M1F7_GULGU/1949-2024  AC A0A3P4M1F7.1
#=GS A0A3Q4I8Y1_NEOBR/2139-2210  AC A0A3Q4I8Y1.1
#=GS M7BLN2_CHEMY/393-469        AC M7BLN2.1
#=GS A0A6Q2XM53_ESOLU/821-898    AC A0A6Q2XM53.1
#=GS A0A4Z2EYT4_9TELE/1254-1320  AC A0A4Z2EYT4.1
#=GS A0A286ZKR8_PIG/1724-1793    AC A0A286ZKR8.1
#=GS A0A3Q3XH60_MOLML/1811-1874  AC A0A3Q3XH60.1
#=GS A0A4X2KNU1_VOMUR/939-1031   AC A0A4X2KNU1.1
#=GS A0A1U7QY57_MESAU/1632-1705  AC A0A1U7QY57.1
#=GS W5MXP6_LEPOC/1991-2056      AC W5MXP6.1
#=GS A0A6I8N4K5_ORNAN/1360-1429  AC A0A6I8N4K5.1
#=GS I3KMG6_ORENI/1063-1154      AC I3KMG6.2
#=GS A0A452EVA6_CAPHI/1959-2033  AC A0A452EVA6.1
#=GS K7GNC0_PIG/657-729          AC K7GNC0.2
#=GS G3S5I1_GORGO/125-201        AC G3S5I1.2
#=GS H3CFS0_TETNG/478-551        AC H3CFS0.1
#=GS F1PS76_CANLF/561-638        AC F1PS76.3
#=GS W5NPU6_SHEEP/160-229        AC W5NPU6.1
#=GS A0A5F9DL12_RABIT/3-56       AC A0A5F9DL12.1
#=GS A0A5E8AVF8_9BACT/2102-2171  AC A0A5E8AVF8.1
#=GS A0A315UZZ1_GAMAF/2041-2110  AC A0A315UZZ1.1
#=GS A0A673WIZ0_SALTR/132-184    AC A0A673WIZ0.1
#=GS A0A5C6RQQ1_9BACT/70-136     AC A0A5C6RQQ1.1
#=GS A0A210PS86_MIZYE/538-610    AC A0A210PS86.1
#=GS G3HBQ9_CRIGR/1144-1213      AC G3HBQ9.1
#=GS A0A0Q5SQT6_9BACT/544-612    AC A0A0Q5SQT6.1
#=GS A0A5F9DGW0_RABIT/1958-2033  AC A0A5F9DGW0.1
#=GS A0A2T7P7V1_POMCA/1524-1584  AC A0A2T7P7V1.1
#=GS A0A4U5U544_COLLU/622-695    AC A0A4U5U544.1
#=GS A0A5F5XVX4_FELCA/2063-2134  AC A0A5F5XVX4.1
#=GS I3KMG6_ORENI/1779-1847      AC I3KMG6.2
#=GS A0A3Q0GX71_ALLSI/1248-1316  AC A0A3Q0GX71.1
#=GS W5KFH9_ASTMX/217-289        AC W5KFH9.2
#=GS A0A4V4H1M4_9BACT/1052-1123  AC A0A4V4H1M4.1
#=GS A0A6J3PZL4_TURTR/1977-2051  AC A0A6J3PZL4.1
#=GS A0A667YX81_9TELE/1359-1432  AC A0A667YX81.1
#=GS A0A6J3PZL5_TURTR/1810-1877  AC A0A6J3PZL5.1
#=GS A0A1S3JML3_LINUN/567-641    AC A0A1S3JML3.1
#=GS A0A4W5RMV0_9TELE/749-825    AC A0A4W5RMV0.1
#=GS R6A5L3_9BACT/876-946        AC R6A5L3.1
#=GS A0A093H3Y3_STRCA/1997-2066  AC A0A093H3Y3.1
#=GS A0A099ZXZ6_CHAVO/201-277    AC A0A099ZXZ6.1
#=GS N6VND9_9EURY/276-341        AC N6VND9.1
#=GS A0A3Q2US80_HAPBU/846-921    AC A0A3Q2US80.1
#=GS A0A5F5Y430_FELCA/1301-1370  AC A0A5F5Y430.1
#=GS A0A484DL47_PERFV/1220-1289  AC A0A484DL47.1
#=GS A0A673TVT2_SURSU/1140-1210  AC A0A673TVT2.1
#=GS A0A485PPX2_LYNPA/536-605    AC A0A485PPX2.1
#=GS A0A1A6HQ82_NEOLE/1751-1818  AC A0A1A6HQ82.1
#=GS W5N2A3_LEPOC/889-966        AC W5N2A3.1
#=GS A0A673W3S2_SALTR/67-118     AC A0A673W3S2.1
#=GS A0A2A3UAQ0_9SPHI/1268-1333  AC A0A2A3UAQ0.1
#=GS G3WU86_SARHA/1397-1463      AC G3WU86.1
#=GS A0A6G1AJL9_CROCR/227-293    AC A0A6G1AJL9.1
#=GS A0A663F4F5_AQUCH/1318-1383  AC A0A663F4F5.1
#=GS A0A3P9APB2_ESOLU/942-1011   AC A0A3P9APB2.2
#=GS A0A094KY15_PODCR/1476-1545  AC A0A094KY15.1
#=GS A0A1Y2RBX2_9BACT/1030-1098  AC A0A1Y2RBX2.1
#=GS A0A3Q2HGX7_HORSE/153-222    AC A0A3Q2HGX7.1
#=GS A0A455B088_PHYMC/1652-1721  AC A0A455B088.1
#=GS W5KUR6_ASTMX/969-1061       AC W5KUR6.2
#=GS A0A4Q7MBC6_9BACT/202-270    AC A0A4Q7MBC6.1
#=GS A0A6I8PFQ0_ORNAN/1239-1310  AC A0A6I8PFQ0.1
#=GS A0A091MDC8_CATAU/333-409    AC A0A091MDC8.1
#=GS A0A3Q1HP00_ANATE/848-926    AC A0A3Q1HP00.1
#=GS W5KUR6_ASTMX/1500-1569      AC W5KUR6.2
#=GS A0A5N4BZA2_CAMDR/1092-1163  AC A0A5N4BZA2.1
#=GS A0A3P9C4W9_9CICH/849-926    AC A0A3P9C4W9.1
#=GS A0A1B9DXV8_9FLAO/132-191    AC A0A1B9DXV8.1
#=GS A0A674DLU3_SALTR/883-960    AC A0A674DLU3.1
#=GS A0A4X2KQ46_VOMUR/1975-2049  AC A0A4X2KQ46.1
#=GS A0A6A1Q3B0_BALPH/506-598    AC A0A6A1Q3B0.1
#=GS A0A1A6HQ82_NEOLE/1412-1478  AC A0A1A6HQ82.1
#=GS A0A4D9EXC8_9SAUR/1837-1901  AC A0A4D9EXC8.1
#=GS A0A512BEQ5_9BACT/741-803    AC A0A512BEQ5.1
#=GS A0A3P4M1F7_GULGU/1274-1344  AC A0A3P4M1F7.1
#=GS A0A267EE90_9PLAT/650-709    AC A0A267EE90.1
#=GS A0A2K6JVP9_RHIBE/1382-1452  AC A0A2K6JVP9.1
#=GS A0A093IN08_FULGA/1662-1731  AC A0A093IN08.1
#=GS A0A239ERN5_9BACT/591-657    AC A0A239ERN5.1
#=GS A0A5C6N1Q8_9TELE/1106-1175  AC A0A5C6N1Q8.1
#=GS A0A3Q2E088_CYPVA/249-323    AC A0A3Q2E088.1
#=GS A0A210PYC7_MIZYE/621-697    AC A0A210PYC7.1
#=GS A0A1S3WHS1_ERIEU/1610-1678  AC A0A1S3WHS1.1
#=GS A0A091HKC7_CALAN/1819-1888  AC A0A091HKC7.1
#=GS E4NV88_HALBP/86-155         AC E4NV88.1
#=GS A0A4U3L494_9BACT/800-862    AC A0A4U3L494.1
#=GS H9GEX9_ANOCA/586-651        AC H9GEX9.1
#=GS F2IA76_FLUTR/1437-1504      AC F2IA76.1
#=GS A0A340X358_LIPVE/1385-1455  AC A0A340X358.1
#=GS A0A3Q7X460_URSAR/290-359    AC A0A3Q7X460.1
#=GS A0A1S3WHS1_ERIEU/1693-1762  AC A0A1S3WHS1.1
#=GS A0A2S2DYG8_9BACT/468-542    AC A0A2S2DYG8.1
#=GS A0A2K5CWY1_AOTNA/225-301    AC A0A2K5CWY1.1
#=GS F6YV18_MONDO/1155-1226      AC F6YV18.3
#=GS A0A3Q2X9E0_HAPBU/849-927    AC A0A3Q2X9E0.1
#=GS A0A4W3IKV2_CALMI/1808-1875  AC A0A4W3IKV2.1
#=GS H2MZP2_ORYLA/969-1039       AC H2MZP2.2
#=GS A0A6I8QJD5_XENTR/1746-1810  AC A0A6I8QJD5.1
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#=GS M3YVF5_MUSPF/1990-2061      AC M3YVF5.1
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#=GS A0A667X791_9TELE/754-831    AC A0A667X791.1
#=GS A0A3G3GTT2_9BACT/135-204    AC A0A3G3GTT2.1
#=GS A0A094LNL3_ANTCR/1246-1314  AC A0A094LNL3.1
#=GS A0A2K5MWB6_CERAT/225-301    AC A0A2K5MWB6.1
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#=GS A0A444UEX9_ACIRT/1525-1595  AC A0A444UEX9.1
#=GS A0A2K6PUS3_RHIRO/1974-2049  AC A0A2K6PUS3.1
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#=GS A0A093PUP2_PHACA/1132-1200  AC A0A093PUP2.1
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