#=GF ID POC3_POC4
#=GF AC PF10448.10
#=GF DE 20S proteasome chaperone assembly proteins 3 and 4
#=GF PI POC1; chaperone_DMP;
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU Wood V;0000-0001-6330-7526
#=GF SE Pfam-B_75798 (release 22.0)
#=GF GA 22.10 22.10;
#=GF TC 22.10 22.90;
#=GF NC 21.60 22.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 17707236
#=GF RT 20S proteasome assembly is orchestrated by two distinct pairs of
#=GF RT chaperones in yeast and in mammals.
#=GF RA Le Tallec B, Barrault MB, Courbeyrette R, Guerois R,
#=GF RA Marsolier-Kergoat MC, Peyroche A;
#=GF RL Mol Cell. 2007;27:660-674.
#=GF RN [2]
#=GF RM 18278057
#=GF RT Crystal structure of a chaperone complex that contributes to the
#=GF RT assembly of yeast 20S proteasomes.
#=GF RA Yashiroda H, Mizushima T, Okamoto K, Kameyama T, Hayashi H,
#=GF RA Kishimoto T, Niwa S, Kasahara M, Kurimoto E, Sakata E, Takagi K,
#=GF RA Suzuki A, Hirano Y, Murata S, Kato K, Yamane T, Tanaka K;
#=GF RL Nat Struct Mol Biol. 2008;15:228-236.
#=GF DR INTERPRO; IPR018854;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family contains chaperones of the 20S proteasome which
#=GF CC function in early 20S proteasome assembly. The structures of two
#=GF CC of the proteins in this family (POC3 and POC4) have been solved,
#=GF CC and they closely resemble those of the mammalian proteasome
#=GF CC assembling chaperone PAC3, although there is little sequence
#=GF CC similarity between them [2].
#=GF SQ 98
#=GS Q75BZ6_ASHGO/1-127 AC Q75BZ6.1
#=GS A0A1G4JZW7_9SACH/1-178 AC A0A1G4JZW7.1
#=GS K0KRH7_WICCF/2-137 AC K0KRH7.1
#=GS A0A1E4RRF4_9ASCO/1-140 AC A0A1E4RRF4.1
#=GS A0A1G4M758_LACFM/1-167 AC A0A1G4M758.1
#=GS G8Y9B8_PICSO/2-114 AC G8Y9B8.1
#=GS A0A1E4TPG2_PACTA/2-99 AC A0A1E4TPG2.1
#=GS G8BVS7_TETPH/1-146 AC G8BVS7.1
#=GS C5DXQ3_ZYGRC/1-112 AC C5DXQ3.1
#=GS A5E1X3_LODEL/1-169 AC A5E1X3.1
#=GS A7TKP5_VANPO/1-142 AC A7TKP5.1
#=GS K0KMZ0_WICCF/1-124 AC K0KMZ0.1
#=GS A0A1E4SSZ8_9ASCO/3-154 AC A0A1E4SSZ8.1
#=GS A0A1L0BLH8_9ASCO/2-108 AC A0A1L0BLH8.1
#=GS POC3_YEAST/1-174 AC Q07951.1
#=GS POC3_YEAST/1-174 DR PDB; 2Z5C E; 2-174;
#=GS POC3_YEAST/1-174 DR PDB; 2Z5C B; 2-174;
#=GS POC3_YEAST/1-174 DR PDB; 2Z5B B; 1-174;
#=GS A0A421JSM2_9ASCO/1-138 AC A0A421JSM2.1
#=GS A0A0C7MSA6_9SACH/1-124 AC A0A0C7MSA6.1
#=GS H2B0N5_KAZAF/1-170 AC H2B0N5.1
#=GS A0A1G4J7H1_9SACH/1-180 AC A0A1G4J7H1.1
#=GS C5DEY5_LACTC/1-123 AC C5DEY5.1
#=GS I2H202_TETBL/1-176 AC I2H202.1
#=GS A0A0X8HWI2_9SACH/1-166 AC A0A0X8HWI2.1
#=GS G0WB23_NAUDC/1-162 AC G0WB23.1
#=GS W6MRP4_9ASCO/2-129 AC W6MRP4.1
#=GS A0A1A0H5C7_9ASCO/2-137 AC A0A1A0H5C7.1
#=GS A0A1V2LB26_CYBFA/2-132 AC A0A1V2LB26.1
#=GS A5DCJ0_PICGU/1-140 AC A5DCJ0.2
#=GS C5M8D9_CANTT/3-107 AC C5M8D9.1
#=GS W0T7X3_KLUMD/1-157 AC W0T7X3.1
#=GS H2AN60_KAZAF/1-145 AC H2AN60.1
#=GS J6ELU0_SACK1/1-174 AC J6ELU0.1
#=GS W0T854_KLUMD/3-149 AC W0T854.1
#=GS G8YL00_PICSO/1-134 AC G8YL00.1
#=GS A0A367YE68_9ASCO/1-153 AC A0A367YE68.1
#=GS A7TFL1_VANPO/1-161 AC A7TFL1.1
#=GS Q75F97_ASHGO/1-173 AC Q75F97.1
#=GS C5DRR1_ZYGRC/1-152 AC C5DRR1.1
#=GS G8JP89_ERECY/1-129 AC G8JP89.1
#=GS C5DCJ0_LACTC/1-168 AC C5DCJ0.1
#=GS G0VBA9_NAUCC/1-145 AC G0VBA9.1
#=GS J7QZS7_KAZNA/1-143 AC J7QZS7.1
#=GS A0A2V1AM97_9ASCO/13-110 AC A0A2V1AM97.1
#=GS A0A1E3PCD7_WICAA/1-124 AC A0A1E3PCD7.1
#=GS A0A1D2VIC4_9ASCO/3-121 AC A0A1D2VIC4.1
#=GS C4Y950_CLAL4/1-131 AC C4Y950.1
#=GS A0A1G4IZI3_9SACH/27-166 AC A0A1G4IZI3.1
#=GS Q6CJW0_KLULA/1-154 AC Q6CJW0.1
#=GS A0A1E3NQD0_9ASCO/1-127 AC A0A1E3NQD0.1
#=GS J6EPJ4_SACK1/1-143 AC J6EPJ4.1
#=GS C5MBS8_CANTT/1-152 AC C5MBS8.1
#=GS Q6BTU4_DEBHA/1-110 AC Q6BTU4.1
#=GS A0A1D2VMJ6_9ASCO/1-166 AC A0A1D2VMJ6.1
#=GS A0A421JAU9_9ASCO/5-132 AC A0A421JAU9.1
#=GS A0A1L0D2X3_9ASCO/1-131 AC A0A1L0D2X3.1
#=GS A0A1E3NFX3_9ASCO/1-139 AC A0A1E3NFX3.1
#=GS A0A099NXK7_PICKU/7-125 AC A0A099NXK7.1
#=GS G8JVU4_ERECY/1-172 AC G8JVU4.1
#=GS A0A1E4SFK7_9ASCO/1-142 AC A0A1E4SFK7.1
#=GS A0A3F2Y6R4_DEKBR/8-149 AC A0A3F2Y6R4.1
#=GS G8ZMU0_TORDC/1-127 AC G8ZMU0.1
#=GS A0A1X7QZH7_9SACH/1-181 AC A0A1X7QZH7.1
#=GS G8YND1_PICSO/1-134 AC G8YND1.1
#=GS A0A367YBS0_9ASCO/1-152 AC A0A367YBS0.1
#=GS A0A1E4RSD7_9ASCO/5-112 AC A0A1E4RSD7.1
#=GS G8BU22_TETPH/1-176 AC G8BU22.1
#=GS S6EDY2_ZYGB2/3-154 AC S6EDY2.1
#=GS G3AND3_SPAPN/1-141 AC G3AND3.1
#=GS G3B2L9_CANTC/1-141 AC G3B2L9.1
#=GS A0A448YQK2_BRENA/3-114 AC A0A448YQK2.1
#=GS G0WG67_NAUDC/1-168 AC G0WG67.1
#=GS G8BL81_CANPC/1-152 AC G8BL81.1
#=GS A0A2V1AVZ2_9ASCO/2-132 AC A0A2V1AVZ2.1
#=GS A0A1E4T2X8_9ASCO/17-135 AC A0A1E4T2X8.1
#=GS A0A1G4KMJ9_9SACH/1-121 AC A0A1G4KMJ9.1
#=GS G0VE71_NAUCC/1-158 AC G0VE71.1
#=GS A3LSI5_PICST/1-111 AC A3LSI5.1
#=GS A0A0C7MYC1_9SACH/1-176 AC A0A0C7MYC1.1
#=GS A0A2H0ZQ19_CANAR/6-132 AC A0A2H0ZQ19.1
#=GS C4XYP9_CLAL4/2-106 AC C4XYP9.1
#=GS Q6FJZ1_CANGA/2-116 AC Q6FJZ1.1
#=GS A0A1G4KG33_9SACH/1-156 AC A0A1G4KG33.1
#=GS Q6CRP5_KLULA/1-144 AC Q6CRP5.1
#=GS A0A2U9QZS6_PICKU/1-163 AC A0A2U9QZS6.1
#=GS G8ZVM9_TORDC/1-138 AC G8ZVM9.1
#=GS J7RDW7_KAZNA/1-169 AC J7RDW7.1
#=GS I2GYN1_TETBL/1-146 AC I2GYN1.1
#=GS A0A1X7R3G6_9SACH/1-150 AC A0A1X7R3G6.1
#=GS A0A2H1A4M0_CANAR/10-106 AC A0A2H1A4M0.1
#=GS A0A1E3QIT2_9ASCO/1-119 AC A0A1E3QIT2.1
#=GS POC4_YEAST/1-143 AC Q12245.1
#=GS POC4_YEAST/1-143 DR PDB; 2Z5B A; 1-143;
#=GS POC4_YEAST/1-143 DR PDB; 2Z5C D; 4-143;
#=GS POC4_YEAST/1-143 DR PDB; 2Z5C A; 4-143;
#=GS A0A2P7YM17_9ASCO/4-128 AC A0A2P7YM17.1
#=GS Q6BIL1_DEBHA/1-137 AC Q6BIL1.1
#=GS A0A1E5R3G7_9ASCO/1-145 AC A0A1E5R3G7.1
#=GS A3GHY9_PICST/1-142 AC A3GHY9.2
#=GS Q6FW35_CANGA/1-166 AC Q6FW35.1
#=GS S6F7P3_ZYGB2/7-120 AC S6F7P3.1
#=GS A0A1D8PFG6_CANAL/1-161 AC A0A1D8PFG6.1
#=GS A0A1G4MHI2_LACFM/1-124 AC A0A1G4MHI2.1
Q75BZ6_ASHGO/1-127 .................................................MTQTKTADYTVSTLG---................-GDDVRLLVTm...pvELT.ASKKVPVSIVVSGRCDGVNEE-----.....................-LAATV...YGV--.............................---..-...-PYK....GSDVVTSVLLDTADNRIR.DF-GSTFCRV.LVKKVGLPC...............-YVSVS.SSVGR......-MLDSGDQLAVIRKALEHL-t...................
A0A1G4JZW7_9SACH/1-178 .................................................MFAREARKIIPNELHL--................-GTNSCLEIS......AVH.FSNNIVLQIRFNGELDTCLEVNWKGIp..................adS----I...GNTPLgsktlhqdqfesn..skdlddedsdsdfeDYK..P...MEDV....LSNFHIATRLGDSNDMKL.PIVCSQIAEL.YQKVVFPSNvdklrd...isltrgFVISLS.AKMWR......-RESSEKDFAVLLFILQTIK....................
K0KRH7_WICCF/2-137 .........................................akpfsdsv-----------------Kyk...........sqkTEDNHEISVQ......SLK.FADKRVLFVKFDGEVDITYDVQAP--.....................-DSKSL...YDI--.............................LSS..S...TISN....DFTCDKTCLMGDGSNIKV.AVIINHIAKL.LYSTSERTG...............LIISIS.SKLFK.....nQQTSNSKDFDILIQILSLIK....................
A0A1E4RRF4_9ASCO/1-140 ...........................................mdaalp-----------QFSKVLVkk............ypQESDVEFTFH......KIE.LSDKIILNVHTNGIIDTTFDIPISSK.....................AAISST...TNS--.............................--I..D...SSEE....GLGVEPIILVGDSSNLKI.QIIASQIGKL.ILLLANPKN...............LILSIG.SRWFG.....kGDEVKDDDFEKLMFVLANIK....................
A0A1G4M758_LACFM/1-167 .................................................MYHREIRKTTPEEIGL--................-GANAIVEIS......AVH.FTNQILLHLRLNGELDTTYEVVPKGLpvddldp.......ppiagtsSFTNDS...LQIED............................eDYV..S...VKDN....LSNYHVVTRLGDSNDMKL.PIVCTQIAEL.YQRIITPSNidgfsq...diskrgLVITMS.AKIWR......-KCRPGYDFHALVFILQSIK....................
G8Y9B8_PICSO/2-114 .............................................ivek------------EIDS--................FGEQYQAVFS......TDF.AKTKGSIGVYINHTENSRIGG-----.....................----YV...YSI--.............................---..-...GDRR....SGEVYGVVLQDSSDEMAV.EH-ARSLGRI.LVKKYGLPA...............-YTCIS.GSVSN.....fGHL-----------------lqsvmaviegik........
A0A1E4TPG2_PACTA/2-99 ...................................evsegfnakslmks------------------................YDSEREFLFQ......VIY.FTNKTILQIHLNGEIDYTIDLQLPKL.....................-ANTAV...YED--.............................---..-...-QQI....ESMIGTNYIIGNNDNYKI.LIMSTQIGKL.FVK------...............------.-----......--------------------dwr.................
G8BVS7_TETPH/1-146 .................................................MSVKTTKKIITPSFSLSS................SVIDIVATIP......TSL.DNKKIPITVNIALID--SNQASEDGEyrsddv.........rdisetNLQCYH...YSI--.............................---..P...SRLK....TQEVVSSVLLDTDNDYIR.DI-TRQLSVL.ICKKYEHPC...............-YVSWS.SNGSI......-NTTSMDHLSVIKECVAFIK....................
C5DXQ3_ZYGRC/1-112 ................................mqtktvshtietplepi------------------................---QLLATLP......-VN.DSKKTPISITISGSAG----------.....................-LACYH...YAI--.............................---..-...--PY....RDDVVGSLMVDDANDSKR.DI-TRQLATL.VAKKYQRPC...............-YVAYA.CN---......---NTEDQLLIIRQC-----ieflk...............
A5E1X3_LODEL/1-169 .................................................MSNQLICVDPSGLSKSFTvnlgstankekeekkeGEEEVSFHFH......LLE.FANKVIINISIDGILDSSFRAPVPTR.....................KVMNYE...SRIDLdddn....................eeeekNDG..S...MGFV....DTSGELELIVGNYSNMKI.SIVAAQVAKL.V-QTKKPKE...............TIVTIG.SRWFG.....nGEEVEDSDFERLMFVLENVK....................
A7TKP5_VANPO/1-142 .................................................MSVQTFSKTLEPSGSISG................KLLDVSVTIP......VDL.SNNKIPITVTIGSKEGGINAGENDTGndi...............nnlKLLCYY...YSI--.............................---..S...RRSD....KNDVVSTVLLDTSIDSVR.DT-TRQLSTL.LCKKYRHPC...............-YVAWS.SDASN......-TNDMFDQISIIKTCVQYIH....................
K0KMZ0_WICCF/1-124 ..........................................msstttv---------STELSPSFG................DPFQASITIPtk..rpSTT.EKNKIPITVFISKTGPDTPFG-----.....................---CYI...YSI--.............................---..-...-IHP....KTSEVFQTILNNSNEGLL.DI-TKKLSNV.LCKKFQSPT...............-YVNVN.GY---......--FDLYDYLGVIKAIT----efie................
A0A1E4SSZ8_9ASCO/3-154 ................................efkdtfkqitqlynddi------------------................--SKFELTCS......ILK.LNNKLIINLYKNGQIDICYDLQLN--.....................-KINKS...QIIYNdyd.......................dddNDT..E...YDDL....TSNLIPIVLIGNSNNMKT.QVLASQIGKL.INEKNISNYn............dnIILHSS.GQFFNnddnddNNDNNDDDFNKLQFII----stf.................
A0A1L0BLH8_9ASCO/2-108 ..........................................ktdtvsv------------------................GEHDYTVAVQ......RSS.DNKKAPILVYVNQVGNESLGC-----.....................----YI...YSI--.............................---..-...-ASV....RECYQSVLQ-GLENGDLH.DF-TANLGRV.LVKRYHCPL...............-YVSLS.GGIS-......--------------------mydygelsravvek......
POC3_YEAST/1-174 .................................................MISYEFQTHLPKGKDSSLn..............aSSENKELYVQ......ATH.FNNTILLQIRLNGEMDSTYEVSSKGLn..................piLDINVP...LAGNLgntgg...................dyddeEEE..F...VRDH....LSDYQVVTKLGDSADPKV.PVVCVQIAEL.YRRVILPEVsgtmaq...dnmqfsLLISMS.SKIWRa...tkEQSADDNDFGKLVFVLKCIK....................
#=GR POC3_YEAST/1-174 SS .................................................--EEEEEEES---------..............------EEEEE......EEE.-SS-EEEEEEETTB--EEEEEEE----..................--------...----------...................----SHHH..H...HHHH....---EEEEEEES-TT-TTH.HHHHHHHHHH.HHTTSS---------...-----EEEEEE-.GGG---...-------SSHSHHHHHHHHHHH....................
A0A421JSM2_9ASCO/1-138 .............................................msii-------EDQTGFSKSLT...............lHNDKTEFFFH......KLS.LADRQIINVQIDGIMDTTFDIPMTTQ.....................ASINYA...SSMEI.............................D--..-...-GDT....IGVPDPVLLIGDHANMKI.SIVASQVAKL.I-ALQCPKH...............TCLSIG.SKWFG.....nGNEVEEGDFEKLMFIVENIK....................
A0A0C7MSA6_9SACH/1-124 ...............................................mv---KTVQRTIENPLGS--................-PIHVLLAQP.....eSDV.NTSKSPISMVISTAANPANQS-----.....................-LLCYV...YAV--.............................---..-...--PT....STDVLSTVLTDTTDDTVR.ET-AVRISKL.CAKKSGKPF...............-YLTIA.SD-GG......PNKMNVDQLLLCKEC-----vslid...............
H2B0N5_KAZAF/1-170 ............................................mlyfe-----FKGEFGPDVK---................SLEGSTLNIS......ATH.FTNQILIQIRASGEMDSTYEVTQRGI.....................RPMEQI...FSRPIagqngvl..............eeneeeeeEFE..T...MRDH....LSDYNVIVRLGDSNDAKI.PVICTQIANL.YQTVILPQSapvlrg..dnfsgvnLLITLN.SKMWR.....qDENDSNVDFAKLVFLLKSIK....................
A0A1G4J7H1_9SACH/1-180 .................................................MYTKEFRTSFGHDLE---................LDKGSVLELS......AVH.FINKVVLQIRLNGELDTCLEVISKGL.....................-PAESM...SSTPLglqvmqrnedqidmpmlaedcndneneinDFT..P...VEDS....LSNFHIITRLGDSNDMKL.PIVCCQIAEL.YQKVIFLSNvdnmrd...vaptrdFVISLS.AKIWK......-SASPGRDFSLLIFILTSIK....................
C5DEY5_LACTC/1-123 .....................mvkttqhtienplgspfhvlvsapepei------------------................----------......---.DTPKSPISMVVSTGANPAAQS-----.....................-LMAYV...YAI--.............................---..-...--GT....ARDVYSTVLVDTVDDTVR.ET-ATRIAKL.CAKKSSRPC...............-YLGVA.GDG--......--------------------gagtlaldqlllcrecvklv
I2H202_TETBL/1-176 .................................................MYQVETTVELPKELF-PQk..............tDIRSSQLTIE......AVH.FINQVLIQIRYNGEMNTTYEISPKSM.....................NTIKNP...TMG-Fgnsvdy................fqddadeSQQ..S...FPNH....LANYQITTRLGNSNDMKL.PVICTEIAEL.YSKIILPSNvdeleti.dsplnrtFMITMS.TKLWYdn.veeSDITTNRDFQKLIFVLKTI-r...................
A0A0X8HWI2_9SACH/1-166 .................................................MYHRELTKEIPVELLRGS................GVDINILSID......AIH.YMNKVVLQIRLNGEMDATAEVKPKGIefs...............psfNSAE--...----Pesfe.....................eeddD-GlfY...VNDE....LSKYNVAIRVGNSNDMKL.PIVLMQIAKL.YDKVITPSNvdrlna...tgtgrsTVITLT.TKFWN.....sENSQGQSDFHKLAFLLNAIK....................
G0WB23_NAUDC/1-162 .................................................MSTRTIHKQIVSDSSSFIs..............lPAIELITTIP......TSQ.ESNKIPISLIVSLGGDNFIDGNVSTLlenegni......kridtqlgTLVSYY...YALPRrt........................srnKSD..T...SIQR....DPEVIGMPLLDTSYDTVA.DI-TRQLAIL.IVKKYHRPC...............-YVAWS.LK--N......GSDLSSLELNQLFIVKKC--me..................
W6MRP4_9ASCO/2-129 ........................................sdnhtqvid------------------................TYENNEISAQ......IIE.FQDKSVIHLALNGEKDTTIDIPLP--.....................--LTPG...IKL--.............................---..A...SEST....SSRISPVVLLGNQQNLKT.MVMANQIGTLfYTFSPEPKN...............LILITS.SKLWN.....eKDDASNADFQKLAFILGLL-k...................
A0A1A0H5C7_9ASCO/2-137 ............................................nandk---------LQAQKQTCTi.............saSFGSDNIDFH......SIS.FTDKLILNIMVNGAMDASFDIPLLTL.....................STINRS...IQQ--.............................---..-...--ED....SLGPEPVVLMGDPNNLKA.QLIASQVGKV.VSQLREPRN...............VILSIS.SRWFG.....kADGIAEGDFEKLMFVLQNVK....................
A0A1V2LB26_CYBFA/2-132 ....................................slnatktitevlq------------------................---GREISVQ......SVD.FADKHLLFVRVDGEADTTFDVKAP--.....................-DANTM...LQLQL.............................GGQ..S...AAE-....DFTCEKTCLIGQNTNLKL.GIAVNQIAKV.LYTNSESRN...............LVISIS.SKLFA......-SPSSGNEFETLVDLLQLVK....................
A5DCJ0_PICGU/1-140 .................................................MQVARIKSPKQNLNSFALektvmntttaisklalFSGDYDVAITg...caART.SQHYPPIAVFITDVAAPRFGS-----.....................----YV...YTI--.............................---..-...GDRK....SGETFATVIHESDADT--.EEMCRNMGRV.LAKKFEVPV...............-YTNIN.GR---......--LDPGSYQELLNHVIDR--as..................
C5M8D9_CANTT/3-107 .........................................hiidgitl------------------................NGLDYTIVVS.....yNHK.FHKKAPITIYINQQGNPEMGD-----.....................----YI...YTI--.............................---..-...----....-SNYSTYLHNSTNNDQ--.---VKSLNQL.LTKKFDVPI...............-FLNIS.GN---......-SISAVSNIEIFKNIVDVI-e...................
W0T7X3_KLUMD/1-157 .............................................mkfv----EHVKELDSEVF---................SDFPGELGIF......ASH.YENKVVVQIRYNGEMDSTYELKSKGL.....................GNQEQE...LALDFgneg....................gdfadDYA..P...VRDP....LSHYDVITKLGDSNDMKI.PIICTQIAQL.YDRVIIPRLggqq......glpsdYVITLS.TKLWR......--KSEVKSFEKLIFLLAAIK....................
H2AN60_KAZAF/1-145 .................................................MSVKTVFKTITSESS-LN................QSIPIEIIATi....pEDL.QASKIPISLTLCYQKDRNNDSKYQIP....................sTFMYYH...YSIPN.............................RLR..T...KKAT....DDDVIGIPLIDTDNDWIK.DI-SRKIANM.VAKKYNKPC...............-YVAWSnTKLMD......NSTISMDQLFVLRSCMEFV-q...................
J6ELU0_SACK1/1-174 .................................................MISYEFRTCIPKESDICSn.............asSTEGNELYLQ......ATH.FSNTILLQIRLNGEMDSTYEVSLKGLnpl...............ldvD--AVP...LAG-Nlentg..................ddlddeEEE..F...ARDH....LSDYQVVTKLGDSTDPKA.PVVCIQVAEL.YRRVLLPEMnsvmiq...gnvqlsLLITMS.SKIWK.....pSREKNGDDFGKLVFLLKCIK....................
W0T854_KLUMD/3-149 ..............................................eli----TFEDTWTTFQGTQT................-MVRCTASPHr...dvATK.HDKRTALSVSICNNWEGPASRMV---.....................-LQGYC...YAIEFvr........................aspASS..A...ASAS....TSAEVCVADLIESRDHVIhDF-IHKIARI.LVLKYHRPC...............-YVQLS.TAAAAs....dDALGASDQINLLQKITQCID....................
G8YL00_PICSO/1-134 ...............................................me--SPQFSKTVVSKYE---................-GDNVEVEFH......KIE.FDDKVIINIKIDGAMDSTFDVPMSNK.....................ALMAAG...DSR--.............................---..-...-VES....DLGIEPVVLVGDSGNTKL.QIVATQVGKV.VATSGRPKN...............TILSVG.SRWFG.....kGDESSEDDFTKLLFVLENVK....................
A0A367YE68_9ASCO/1-153 ................................................m--STEISQDPTGFSKSFRst............yqNDTEDEFFFH......IIN.YANQQIINIAINGLLDTTFELPVSTK.....................STINYA...SSMEIqtd.......................gydEEE..E...DRER....EVIPEPVLLIGDHANMKL.LIVASQVSKI.V-SVTSPKP...............TILSIG.SKWFG.....kGDEVHEDDFERLMFILENVK....................
A7TFL1_VANPO/1-161 .................................................MYTRQSTNQLPLDLF---................-PGGDELAIN......ATH.FTNEILIQLRFNGELDTTYEVSQKGL.....................-NTNSV...IQRPIaspsf...................lnnedDED..T...ITDY....LSDYQVITKLGNSNNMKL.PVICTQIAEL.YNKVILSNQndi........snknLLITLS.SKLWKdn.dndNNNNNNNDFDKLIFVLKCIK....................
Q75F97_ASHGO/1-173 .................................................MIYRELQKAIPPALWGLD................ESAQNELELT......AVH.FTNKTLLHIRFNGEMDATYEVQPRGAg...................gLAADVG...GLHGGaassl..................raegndEDE..F...VEDH....LSKYNVSMKMGNSNDMKL.PVVVMQIAEL.YERAVYPSVlgaear...agpdlgLLVTLS.SRFWRsa..saGGPGSGSDFDRLMFVLQSI-r...................
C5DRR1_ZYGRC/1-152 .................................................MYHKEFTVEFPKDVL---................--PGGELELH......SVH.FNNKILLQVRYNGEMDATYEVVPRGL.....................EPLQRP...LAG-Fs..........................vdEDD..F...SGDH....MSDWQVICRLGDSNDAQL.PVVCTQIGEL.YRRVIIPSNvdglyqn.deiqsrgLVITMS.SKMWK......---GNDKNFDKLIFVLGSIK....................
G8JP89_ERECY/1-129 ..................................msitktnqhvfetfl------------------................-GNQIELLITk...ptDAS.QSKKVPLSIIISTSASNGVGNNN---.....................-LLATV...YGI--.............................---..-...-PYR....DNEPVTTMLVGLEHDETK.DF-VTRLCRI.LVKKFCLPT...............-YVSLS.GRPGQ......-SLSSAEQLSIIERCIEHV-t...................
C5DCJ0_LACTC/1-168 .................................................MFCREIRKVVPSDLNL--................-GADNTLEAV......AVH.FTNKVVLKLRFNGELDTCYEILSKGLpaeg.............lgstPLGKVV...LNSGIgped.....................edfeDLS..P...IEDG....LSNFHVTTRLGNSNDMKL.PIVCTQIAEM.YQKAVLPSNidglrd...iapsrdFVVSLS.AKMWK......-RDTSETDFALLVFILQTIK....................
G0VBA9_NAUCC/1-145 .................................................MSVRTIGKVILSEDSIIS...............vPAIQIIATVP......TDP.TSKKIPISLSICYGGEISTNDS-ETNktn..............mkqsKLMSYY...YAL--.............................---..P...HRRK....EDDVIGVPLLDTNNDIIR.DM-TKRLALL.MVKKFNKPC...............-YVALS.IASES.....dSNSLASNQIFVIKKCIDF--vv..................
J7QZS7_KAZNA/1-143 .................................................MSVRTVIRDLKSDEDASV................-SVPLQLVATi....pTDE.ANTKIPISISVSYLNGGATGAQRAGT....................aKLQSYH...YAV--.............................PNR..R...ASHK....KDNVADMPLLDTNNDWVR.DL-TRKIAVS.VAKRHGKPC...............-YVAWA.SNTEL.....nGNGLSMDQLFMLKSCISAID....................
A0A2V1AM97_9ASCO/13-110 .....................ytvsvtrgeapkkpnvvyvteqapcgig------------------................----------......---.--------------------------.....................---CYI...YAI--.............................---..-...-PGK....KSDVYTAVLQASGDNTVS.DL-AHRLGRV.LVKKSGCPS...............-YVCVS.GSVSEl....dQME-----------------lmgrvvamvs..........
A0A1E3PCD7_WICAA/1-124 .............................................msft---RTFSTELDPNFG---................EPFQILVTIPse..kpSQT.ERNKVPITIFISKEGPNTQFG-----.....................---CYI...YSI--.............................---..-...-VHP....KTSQVYQTILNNSNEGLL.DI-TKKLSNV.VSKKYKVPA...............-YVNVN.GY---......--FDIYDYMGVLKTVLEYID....................
A0A1D2VIC4_9ASCO/3-121 ..................esfsktyseelaapfsdpihicltipskrpt------------------................----------......-LS.EKNKIPIIVFLSKTGGNSDFG-----.....................---CYI...YSIPN.............................FLL..N...RSND....KQNEIVSTILNDSEENLL.DI-TKRLSQL.ISKKFNCPS...............-YVNVS.GN---......--------------------idimes..............
C4Y950_CLAL4/1-131 .............................................mest----------SGSKEIID................QYENDHFSFQ......LIE.FDDKIILNVMINGIVDTTLDIPMPTQ.....................SHINDP...LQ---.............................---..-...-DEQ....SLGVEPVVLLGDPHNIKI.QVVASQIGKV.VQLSRRPRN...............IILSIA.SRYFG.....kGDVTQDGDFEKVMFVVQHVK....................
A0A1G4IZI3_9SACH/27-166 ..........................................ihtndie-----------QQGGFLTgp...........vqrSSQMVKTTAHe....iENP.FGSKVHVQVSIPENEINSPKSPISMViatga...........tpaaqTLQTYV...YAI--.............................---..-...--PR....AQEVLSTVLVDTSDDSIR.ET-ALRVAKL.CAKKSQRPC...............-YLSMA.G----......--------------------ghgaggfgldqvslcke...
Q6CJW0_KLULA/1-154 .................................................MRFIEFQKQLDPEVFS--................-DFPGELGIF......ANH.YDNKIVLQLRVNGEMDSTYEVKSKGL.....................NDTEAR...FVLDGgd........................ddsDYA..P...VNDP....LSHYDVITKLGDSNDMKI.PIICTQIAQL.YERVILPTLgsevg.....asvpdFVITLS.TKLWR......--KSQSNEFEKLIFLLNAVK....................
A0A1E3NQD0_9ASCO/1-127 ................................mpatkdtqtltakispv------------------................FGDEFEVAATlphkrpSLR.ERNRIPISLHLSKVGNNAPLG-----.....................---CYV...YTI--.............................---..-...VDSR....TGKVY-QTLLNNSEEQLV.DM-TRKIGGL.VSKKFSVPT...............-YISMS.GDWSL......--------------------edmvttvkevvkfvd.....
J6EPJ4_SACK1/1-143 .................................................MSIRTVIQSIESESGFLQ................PALDIVATIP......VDA.QSNKIPISLVVGFKQEYPLKSASS--.....................-LACYY...YAIPLt..........................kdRYM..N...SKSG....GSGVVGIPLLDTNNDKIR.DI-ARRLATI.ISEKFKRPC...............-YITWS.SLPDE.....dSSMLIANHLYILNKCLNFLK....................
C5MBS8_CANTT/1-152 ................................................m-SS-EIIQDPTGFSKSFRst............ysNDTNNEFYFH......IIN.YSNQQIINISINGLLDTTFELPVSTK.....................STINYI...SSMEIqn........................dgyDEE..D...DRER....EVIPEPVLLIGDHANMKL.SIVASQISKI.I-SVTSPKP...............TILSIG.SKWFG.....kGDEVHDDDFDRLMFILENVK....................
Q6BTU4_DEBHA/1-110 ..............................................miv--------TKQENIN---................-GDDYQIVIS......-ID.KHDKSSINVYVNEMTNTSVGS-----.....................----YV...YSI--.............................---..-...NDKK....SGQIYSSVLQDHSSNIVT.EQ-ARNLGYL.VVKKYCRPS...............-YTNIN.GQ---......----ISDYPQVLKVVFNLL-d...................
A0A1D2VMJ6_9ASCO/1-166 .................................................MSSNSFESSLKTKSKVI-................-DQSNELKVQ......LNL.FSNKIIIIVSYNGEIDSAYHLKIPNS.....................ASISSY...SSLDYdylrndnn............dgssddldaLNE..D...FNYI....SINTMPVCLMGDPTNLKL.QILSTQVLKL.MISLNKNESr.............nIIIQLS.SKIFKgs.yknKNDVTEMDFDVLYQVLDL--fk..................
A0A421JAU9_9ASCO/5-132 ...............................stlthsaqypngptidyv------------------................----------......LTE.LEDKIILHIRIDGAMDSTFEIPVSTS.....................DTMRLV...SGT--.............................---..-...-QGE....DTLIEPRLVVGNHANFKI.QIVAGQIAKL.MLQSKNPKD...............TFLSIG.SRWFG.....kGDEAETQDFDKLMFVVENL-g...................
A0A1L0D2X3_9ASCO/1-131 .........................................mensnqfl--------------ETVA................EYDQDSLRFQ......KIE.FANKLILNVLTNDIMDTTLDIPLSTQ.....................------...ATI--.............................NDG..L...SDED....SLGVEPVVLVGNPHNLKI.QVVAGQIGKV.VRQLKNPRN...............VILSLG.SRWFG.....sGDSTEDGDFEKLMFVLGNIK....................
A0A1E3NFX3_9ASCO/1-139 ................................msignfrdnvkeldlii-----------------K...............rDGREHMLTCT......MLE.FSDKLIIHLSMNGETDISYDIQIPEK.....................NDLKKP...LRR-Yd..........................fdEEK..E...QEEL....ENTIIPIVLIGSGNNMKM.QVLSSQIGHT.ISQLSNKNI...............-ILNIS.GKLFG......--------------------rayldeyrpgdsv.......
A0A099NXK7_PICKU/7-125 ........................................kihtvttkv---------TPPFGDEFQ................IAATLPLEKP......IFN.ASNRIPITIHLSKTGTN-TE------.....................-LGCYV...YTI--.............................---..-...-LDK....RSGRTHQTLLNNSNETLV.DM-TKKIGAL.LSKKYHVPT...............-YVSVS.GNWS-......--------------------ledllatiksvva.......
G8JVU4_ERECY/1-172 .................................................MFYKELHKGITKDLFSGP................EDGANEVTIC......AVH.FSNAIQLSIRLNGEVDASYEVKPKGIsrsv............gdvgpLTLEML...EGEDGd..........................ddESV..Y...VDDH....MSRYHITTKMGAADDQKL.PVVCMQIAEL.YRRVIVPANldgrae...dapnhhMLITLS.TKFWRrg..gtANHAKGNDFEILVFLLQSIK....................
A0A1E4SFK7_9ASCO/1-142 ...............................................ms----TITKDPTGFTTSFSdy............ynDDRDTEFFFH......KIE.LADKMIINVQTNGIMDTTFELPISSR.....................MAITHD...AMI--.............................---..S...PEIG....DAGIEPRLIVGNHSNLKI.QIVATQIGKV.IATSRNPKD...............TILSIG.SRWFG.....rGDETNNEDFDRLMFILGNVK....................
A0A3F2Y6R4_DEKBR/8-149 .................................................-TTREISRNLELNNDKGF................IQSNIELTCN......IVE.FANKIIVSILQNGEMDLSFDVPLPKL.....................----KE...GKIPF.............................NDD..E...TDTYdvvlDNQVSSTQLLGGVYNMKN.QVAVSQIGKL.LAQYQNKNV...............-ILNMS.GRLFS......GTEFNPNDFTKLKFIIKLVK....................
G8ZMU0_TORDC/1-127 .................................................MSTRTVSHTVSSPVSS--................-PIELIATLP......TDP.QSRKIPITVILGFKTVEDEEP----M.....................SLASYH...YAI--.............................---..-...PYRD....TDQVVSTPLLDTNNDWIR.DI-TRQVATI.MCKKFHKPC...............-YVGWS.NALGQ......--HTTPDQLFVVKNCIE---fin.................
A0A1X7QZH7_9SACH/1-181 ................................mseytasatfnndqgsl------------------................--SGLPLDIT......SIH.FSNQILLQIRLNGEMDSTYEVTKRGL.....................NALDQG...ISRPIagfnsvpse..........eqndddefsyNAD..V...VRDN....LADFQVVTKLGDTTDHKM.PVICTQMGEL.YQSVIIPMLrtsgksneltcdgssLIITIS.SKIFRqpkgedQDPDNELDFAKLVFVLKTIK....................
G8YND1_PICSO/1-134 .................................................MESHQFSKTVVSKYE---................-RDNVEVEFH......KVE.FDDKVIINIKIDGAMDNTFDVPMSNK.....................ALMAAG...DSR--.............................---..-...-VES....DLGIEPVVLVGDSGNTKL.QIVATQVGKV.VATSGRPKN...............TILSVG.SRWFG.....kGDESCEDDFTKLLFVLENVK....................
A0A367YBS0_9ASCO/1-152 ................................................m--STEISQDPTGFSKSFRst............yqNDTEYEFFFH......IIN.YANQQIINVAINGLLDTTFELPVSTK.....................STINYA...SSMEIqt........................dgyDEE..E...DRER....EVIPEPVLLIGDHANMKL.LIVASQVSKI.V-SVTSPKP...............TILSIG.SKWFG.....kGDEVHEDDFERLMFILENVK....................
A0A1E4RSD7_9ASCO/5-112 .........................................kcievldc------------------................---EYQVVIN......-RP.SQEKSPITVYINQISNALVNC-----.....................----YI...YTI--.............................---..-...-LNP....LTHQVYSTVLQNTDNHQLfDI-TKNLGHM.LTKKYQCPS...............-YVNIN.GD---......--LTLEYYTMLLKAVID---iie.................
G8BU22_TETPH/1-176 ..................................mysqeakftefpinl--------------FNIA................NEESRELYIS......SIH.YSNYVLLQIRFNGELDTTYEISQKGLrsv..............sfdrP-----...----Lagslmmn..............deqrsdddEFD..F...TIDN....LSDYQIVTKLGNSNDMKL.PVICTQIVEL.YNKIILPKLhpdkkd...disknkFIITLN.SRIWGsnpnadSSTSSNVDFNRLVFLLKCIK....................
S6EDY2_ZYGB2/3-154 ..................................ckdftvsfpadilpa------------------................----TELSLH......SVH.FSNKVLLQIRYNGEMDTTYEVVPKGL.....................QPISRP...LAG-Lqv........................eqeEEE..F...SGDH....MADWQVICRLGDSNDTKL.PVICTQIGEL.YRKVVLPSNldgmahq.devqsrgLIITLS.SKIWR......---SDENSFDKLVFVLKSLK....................
G3AND3_SPAPN/1-141 ................................................m----TITEDPTGFSKSFIah............fnDNDKTEFFFH......KLT.LADQQIINVQMDGVMDTTFDIPMTTQ.....................ASINYA...SSM--.............................--E..I...DGNT....LGVPEPVLMIGDHANMKI.SIVASQIAKL.IALRSPRHT...............-CLSIG.SRWFG.....tGDEVQDGDFEKLMFIIENIK....................
G3B2L9_CANTC/1-141 .................................................MSEPKFSTHLTKTYP---................DADNTEVTFH......KIE.AADTIILNVLTNGIADTTFELPLNSQ.....................HSINIL...SNL--.............................SNF..E...DDEE....KMGIEPRVIVGDHNNLKI.QVVASQIGKL.LLSNMSEPK..............sVILSIG.SRWFG.....kSTETNDEDFKKLMFVLTSV-n...................
A0A448YQK2_BRENA/3-114 ..................................ftttlattivpdfqi------------------................-----LLTVP......TNS.DAHTIPITLHVSKEGANTKLG-----.....................---AYV...YSI--.............................---..V...DTRR....SERTVYQSLLNNSDEESV.DL-AKKLGTL.VSRRYSVPS...............-YVSVS.GEV--......--------------------gieeylpmsrevi.......
G0WG67_NAUDC/1-168 ...............................................ma--FYKLTKQFDENLL---................--QGQELTIT......AAH.FRNQTIVQIRLEGQIDSTYEVTLEGI.....................SSLEHS...LTRPLagrqflnenq.........ggvdvdedidSSH..F...IRDN....LSDYKVVTKLGDPDDTQL.TVISSQIAEL.YNSVIIPKFqpshe....mdnngkFLISIS.SKIWK......--GDGSAAFQKLVFILQSIK....................
G8BL81_CANPC/1-152 ...............................................ms----EITQDSNGFSKSFA...............vTHADHEFFFH......LIS.FANKQILNISIDGILDTTFKIPVSTK.....................ASINYE...SMMDLiere....................dvdddGQE..F...TSAG....QLPPEPQMIIGNYSNMKI.SIVASQVGKL.MSIHSPREV...............-ILSIA.SKWFG.....kGDQVCEDDFDKLSFILENVK....................
A0A2V1AVZ2_9ASCO/2-132 .....................................asvdnkpkdisc-----------------K................GPDGADFEFQ......RVS.FEDKLVINILIDGVMDTSFDLPLSTS.....................KAIDSS...VLT--.............................---..-...-SED....SLGVEPVVLVGDPHNLKL.QVVAGQIGKV.VYSSGNRRN...............VILSMG.SRWFG......-RETQDGDFEKLMFVLEKVK....................
A0A1E4T2X8_9ASCO/17-135 ..vttvtplfsdpfqlvlvvpiqkpikgernlvpitihisltgsdapig------------------................----------......---.--------------------------.....................---CYV...YSV--.............................--M..D...IRRK....DAQIYQ-TLLNNAEETLV.DL-GKRFGQL.VCKKFYAPC...............-YVSLS.GDLQ-......--------------------vgnfmdyirevfglie....
A0A1G4KMJ9_9SACH/1-121 ................................................m--VKTIQHTIQNPLGS--................-SFQVLVSIP......ENEiNTSKSPISMTIMTGSNAADQA-----.....................-LMIYV...YAI--.............................---..-...--PT....ARDVLTSVLVDTADDAVR.ET-AVRVSKL.CAKKSQRPC...............-YLTMA.GNAS-......--------------------ieslgmdqlllckecvg...
G0VE71_NAUCC/1-158 .................................................MTSFQLQKDFPSTLI---................-ESSPELSLN......AIH.FSNQILIQIRLDSELDSAYEVTEQGLae................megVNSEL-...----Gytnnv...................eesndDTQ..L...ANDD....LSTYHIVGKLGDPDNSKL.KVVCSQIAKL.YNTVIIPNLgme.........kcpILISIS.SKLWRt....qNEATHANDFGKLVFLLGSIK....................
A3LSI5_PICST/1-111 ...........................................mihrsr----------EVNVD---................-GVDCVVVAS.....ySQS.DSSRTPVTVYVNELNNAAMGD-----.....................----YV...YAI--.............................---..-...----....-GQSQTFLHHGTSSESGSgSGSIESLNLL.LNKKLQRPV...............-YLNVS.GA---......---AQVSTVSMFRAIVEVID....................
A0A0C7MYC1_9SACH/1-176 ....................................mfaadyrtyipdd-------------LQ---................LGSNCVLETS......AVH.FNNKVLVQIRFNGELDQCLEVTSRGLpassfeatklydevfqnssqqKEENKN...YEFDN.............................DDD..SftlAEDY....LSNFQISTRLGDSNDMKL.PIVCSQIAEL.YYKVIFPSNadklrd...vaptrdFVISLS.GKFFR......-KSSTDNDFRILLHILQAI-r...................
A0A2H0ZQ19_CANAR/6-132 ......................................rrpreilcegp------------------................--EGAQFAFY......AVL.FDDKLVLNILIDGVMDTSFDLPLSTS.....................KVIDSQ...VLA--.............................---..-...-SDE....SLGIEPVVLVGDPHNLKL.QVVAGQIGKV.VYSMGNRKN...............VILTMG.SRWFG......-KDPKDGDFDKLMFVLGKIK....................
C4XYP9_CLAL4/2-106 ..........................................ksavisv------------------................GGNDYQVIFH......RDK.ANAKAPTMVYVNQVGNSSIGA-----.....................----YV...YTI--.............................---..-...-GKG....TETYTSVLQQGES-MTIQ.DL-AANLGRV.LTRRFAAPS...............-YVCMS.GSLSM......--------------------ydygevssfvv.........
Q6FJZ1_CANGA/2-116 ...........................................sqivvd------------------................-GLSVRVDCD......-VE.DGVKSPISLNLCLSGDEELKSSR---.....................-LECYY...YTI--.............................---..-...-MGR....KDDVLGIPLRDTSSDWIR.DL-ARLCATM.ITKKYNKPC...............-YVTIS.TVGE-......-NNFQASTIPLLAAVKEHV-a...................
A0A1G4KG33_9SACH/1-156 ................................................m-FHKRVTVVVPEDLK---................HGNGRVLEIF......AIH.FSNKIVIQMAWNGEMDSTYEVISKGL.....................AETETG..pNTLEFs..........................deDDV..Y...GPDK....LANFQVVTLLGDANDMKT.PIVCTQIAEL.YQKVVFPAQidglgg...nerdsrFVISLS.RKLWQ......-NNESNADFGLLVFVLQSI-r...................
Q6CRP5_KLULA/1-144 .................................................MTTLTFQDTWTSFEGTPT................-SVRCTTSPHr...dpIVS.QDRKTALSIAIYLNCGDLSSGDSRTY.....................-LQGYC...YGIEF.............................VGR..V...QSTP....KSNEVCVADLIESNDHQIhDL-IHKVTRI.LVLKYHRPC...............-YVQIA.SKTAE......FTLNGADQINMLQNITKCID....................
A0A2U9QZS6_PICKU/1-163 .................................mskgfsnqikesnmnv-----------------Vl..............lDGAQHMITCT......LLE.YLDKIIINMAVDGEIDISYDIQVPEL.....................NVIEKPvrkYDHDFedeeeet...............rddripvKEE..-...-ECL....NSTIIPTVLIGAGHTLKN.QVLASQIGHM.MAQHTNKNI...............-ILNMS.GKLFGkp..saQSEYHEKDSELL--------tmakhlia............
G8ZVM9_TORDC/1-138 .................................................MFHRESTVELPSQLG---................---GGELSVL......AIH.FTNQVLLQLRYNGELDTTFEVSRQGL....................gQLHQMG...SNG--.............................---..E...LRDT....MADYKAVSKLGNSDDAKL.PVVCTQLAEL.VFRTVVDGIetf........eprnLLVTMS.SKLWY......---HGSHDFETLMFVLKTIK....................
J7RDW7_KAZNA/1-169 .................................mphftststfpeelit------------------................LPEGSSLEVL......AVH.YTNYVLLQLRLNGEMDCTVEVSRRGL.....................SSVGQD...SLG-Npiagfsga.............pdleddadEQD..F...ARDN....MADYHVITKLGDPNDTKT.PVIATQIAEL.YQRVILPNVpgslkqstedpastsLIVTLS.SKIWR......---DDTEDFQKLVYVLQTIK....................
I2GYN1_TETBL/1-146 .................................................MYTKTIKTSIVSPLNDSQ................-SIEIILTIPe....aIDQ.QSKKIPVSMVLYHNDNYRPET--TGIdq................dkvKLISYH...YAVPY.............................---..T...KNNG....RTEVVSTPLLDTNVDLYR.DL-TRQISTL.LVKKLNIPV...............-YVAYG.ELIGAp...vsQSAIPMDQLFILR-------kciafve.............
A0A1X7R3G6_9SACH/1-150 .................................................MATRTITHYITPEDSPLG...............gTSLEIIATIG......KDL.SSKKIPISLTICYQKDKP-EIDEQGKvisk.............tqssTLQYYH...YSIPN.............................-KL..R...NRKN....NEFVIGIPLLDTNNDWVR.DI-SRKLADA.TAKKYEVPC...............-YVSWS.TTKPS.....dVTSISMDQMFVLRNCINFI-n...................
A0A2H1A4M0_CANAR/10-106 ............ageytvsvtkgdapkkpnvvfvtensstdigsyiyav------------------................----------......---.--------------------------.....................------...-----.............................---..-...--PG....KKDVFTAVLQGSADSRVQ.DV-ATRIGTL.LVKKSGCPS...............-YVCVS.GAVSE.....mD-------------------emelvrevlt..........
A0A1E3QIT2_9ASCO/1-119 mttykqqispafgggdavdicltlpegaatrvpitlfvspngvneafgp------------------................----------......---.--------------------------.....................----YI...YAI--.............................---..-...PDPR....TGSIYHTVLNGSDDMDQM.EL-TKRLATI.ISKKYRVPS...............-YVSIS.GK---......--IDVYDSIHYIKAIVDLI-d...................
POC4_YEAST/1-143 .................................................MLVKTISRTIESESGFLQ................PTLDVIATLP......ADD.RSKKIPISLVVGFKQEASLNSSSS--.....................-LSCYY...YAIPLm..........................rdRHI..N...LKSG....GSNVVGIPLLDTKDDRIR.DM-ARHMATI.ISERFNRPC...............-YVTWS.SLPSE.....dPSMLVANHLYILKKCLDLLK....................
#=GR POC4_YEAST/1-143 SS .................................................XXEEEEEEEE--------................--EEEEEEEE......SS-.SSSSS-EEEEEEE----------E--.....................-EEEEE...EEEES-..........................S----..-...----....---EEEEEEE--S-HHHH.HH-HHHHHHH.HHHHHTS-E...............-EEEEE.E-TT-.....-THHHHTTHHHHHHHHHHHHH....................
A0A2P7YM17_9ASCO/4-128 ..................................kpteiqgtapdgagf------------------................-------RFY......KVD.FVDKLVVGIVVDGVMDALFDLPLSTL.....................KV----...--I--.............................DEG..V...MKED....SLGVEPVVLVGDPQNLKL.QVVAGQIGKV.IYSLGNRKN...............VILSMG.LRWWG......-RDTEEGDFDKLVFVLEKV-r...................
Q6BIL1_DEBHA/1-137 ...............................................me--------STPEFSKSITat............fpGDEENEFTFH......KIE.LNDKIILNVLINGVMDTTFDIPVSSK.....................SSINAY...SNL--.............................---..S...ISE-....DGGVEPVIIIGDYSNLKI.QVVASQIGKL.VLVSQEPKN...............LILSIG.SRWFG.....kGNETDENDFNKLMFVLDNVK....................
A0A1E5R3G7_9ASCO/1-145 .......................................mqyretlvkt------------------................-ANNAEIHIC......CQF.FANRVLVQIRWNGELDTSYSV---TC.....................QDITQV...LEEXHnyged..................geatdgXDG..F...YQDP....LSNYQITTLFGDSNNLEL.PIIASQVSEL.FIKNKDRVPni...........gsFVVMLS.SKLFH......--AQDNTKFDTLLTILAAIK....................
A3GHY9_PICST/1-142 ................................................m---TEIQKDSTGLSSAFSay............ykDDRSTEIFFH......KIE.YADRMVLNIQFNGVMDTTFEIPISSR.....................ATINYS...AAL--.............................---..S...NSDS....DLGVEPVLLVGNHANMKI.SIVAAQIGKL.ILASANPKS...............AILSIG.SKWFG.....kGDETEDSDFEKLMFILENTK....................
Q6FW35_CANGA/1-166 .................................................MQVRSIRRKLDAQID---................-AAEGEVAVK......ALH.YSNSVVLQIRYNGEFDSTYEVNSVGLrpgsm...........tngrpLALNTY...ASEDNsqngg..................sgeideETE..E...PTDY....LADYKVVVRLGNGDDPKM.NIVCSQIAEL.YNQMQGGDElr..........gvnLVISLS.RKLWK......GEDSHSRDFAVLVFLLQCIK....................
S6F7P3_ZYGB2/7-120 ......tvyetietplecvdvvatlpapaevssgtkkppislvvgasks------------------................----------......---.--------------------------.....................PLLCYH...YAV--.............................---..-...--PY....KQDVVGSVLVDSADDAVR.DV-TRQLATL.VAKKFGVPC...............-YVGWG.CA---......---SASDQLLVISKCIQLIK....................
A0A1D8PFG6_CANAL/1-161 .................................................MTTKLI-QDPTGFSKSFEttyp.......ndtssSSSTNEFFFH......IIN.YSDKQILNISINGLMDTTFELPVSTK.....................SAITYA...SALEIpidq....................fddehEQE..E...IRER....EVIPEPILLIGDHSNMKL.SIVATQISKL.I-SNNCPKP...............TILSIG.SKWFG.....kGDEVDDNDFEKLMFILANVK....................
A0A1G4MHI2_LACFM/1-124 .................................................MSCRTFQHQFSSPLG-AT................FSLLATVPA-......ESH.ADRATPISLVISAGPPSQPQP-----.....................-LTAYV...YAI--.............................---..-...-AAR....DGRVLSTVLLDTPDDAIR.ET-ATRLCKL.CTSKLHRPC...............-YLSFA.SAG--......--------------------gaaagasldteallickqt.
#=GC SS_cons .................................................XXEEEEEEEC--------................--EEEEEEEE......CCE.SSSSCEEEEEECCB--EEEEEEEE--.....................-EEEEE...EEEES-..........................SSHHH..H...HHHH....---EEEEEEES-TTHCCH.HHHHHHHHHH.HHCCCTS-E..............EEEEEEE.CGCT-.....-THHHHTTHCHHHHHHHHHHH....................
#=GC seq_cons ....................................................................................stphplthp......thp.hssKlhlpltlsuthDsoh-s...t........................hshh...hsh.........................................psp....psshtsssllGsssshph.sl.ssQlucL.lscphpsss................hlolo.u+hht.......p.sptsphthLhhllp.l.....................
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