GenomeNet

Database: Pfam
Entry: PRR20
LinkDB: PRR20
Original site: PRR20 
#=GF ID   PRR20
#=GF AC   PF15708.5
#=GF DE   Proline-rich protein family 20
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:P86478
#=GF GA   27.00 27.00;
#=GF TC   39.50 39.30;
#=GF NC   26.40 23.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR031439;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is found in eukaryotes. Proteins in this
#=GF CC   family are typically between 73 and 221 amino acids in length.
#=GF CC   There is a conserved AYV sequence motif.
#=GF SQ   31
#=GS G5B329_HETGA/1-232       AC G5B329.1
#=GS A0A0D9RYI1_CHLSB/1-224   AC A0A0D9RYI1.1
#=GS G3SED8_GORGO/1-210       AC G3SED8.2
#=GS H2NK02_PONAB/1-221       AC H2NK02.1
#=GS A0A2I3H0L3_NOMLE/1-221   AC A0A2I3H0L3.1
#=GS A0A096NRJ7_PAPAN/1-223   AC A0A096NRJ7.2
#=GS F7F3A7_CALJA/96-169      AC F7F3A7.1
#=GS H2NKF9_PONAB/1-203       AC H2NKF9.1
#=GS A0A2K5IV36_COLAP/1-222   AC A0A2K5IV36.1
#=GS A0A2K5KTC7_CERAT/1-223   AC A0A2K5KTC7.1
#=GS A0A2K5IU67_COLAP/1-223   AC A0A2K5IU67.1
#=GS PR20A_HUMAN/1-221        AC P86496.1
#=GS D3ZF00_RAT/8-158         AC D3ZF00.2
#=GS F6W2Q4_MACMU/1-219       AC F6W2Q4.2
#=GS A0A0D9R7U8_CHLSB/1-208   AC A0A0D9R7U8.1
#=GS A0A2I3SJ84_PANTR/1-210   AC A0A2I3SJ84.1
#=GS A0A2I3HGU6_NOMLE/1-221   AC A0A2I3HGU6.1
#=GS A0A2K5KWM1_CERAT/1-147   AC A0A2K5KWM1.1
#=GS PR20E_HUMAN/1-221        AC P86478.1
#=GS A0A091E1W6_FUKDA/78-302  AC A0A091E1W6.1
#=GS G3RNF4_GORGO/1-156       AC G3RNF4.1
#=GS G7PVG9_MACFA/1-223       AC G7PVG9.1
#=GS A0A2I3MYZ3_PAPAN/1-214   AC A0A2I3MYZ3.1
#=GS PR20B_HUMAN/1-221        AC P86481.1
#=GS F7F3A7_CALJA/1-100       AC F7F3A7.1
#=GS G1U7J3_RABIT/8-100       AC G1U7J3.1
#=GS S9XAG5_CAMFR/1-197       AC S9XAG5.1
#=GS PR20D_HUMAN/1-221        AC P86480.1
#=GS PR20C_HUMAN/1-221        AC P86479.1
#=GS A0A2K5M8K6_CERAT/1-224   AC A0A2K5M8K6.1
#=GS H2NKF5_PONAB/1-203       AC H2NKF5.1
G5B329_HETGA/1-232                  ........MEEQRPPKRPRAVAPDPASDGDLRESDYPGVEPEDPGEA...DGPVEPGQPEKPIAYVNPMRCEVPVHAEPAEP.AQRGrirRRP..RQTGRAHTRRqSRRAGRRSRWETDSQEQL......EESQEQleesqelDVH.GQVDDQEEPSHV-DVEARWTPPFSFI-TAP---TVHEdevsGHRSHPTQVAGEIREPSPVSGYWAVLGRQISAIYPCIGFIPLLGSS-LHFMETSFGTHVFGVPVFFTNIAR..............................
A0A0D9RYI1_CHLSB/1-224              ........MEEPRRSKRLRYMAPNQASGGRPTEPFCSVVDPEDSVEVqstESHAEPVQPAKPIAYVKPLRWEPPARTESAPP.AERG...RRR..GGSRLA--GR.GRGRVSGPRRDAGQRQRA......ERLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFPETAPVPGTVQE....GPGPDVAHPEVRHQDPLPASGPEANAWEPMLTIYPCIGFRALGGSAVLQVIQTANGTYVQGIPVFVANIAY..............................
G3SED8_GORGO/1-210                  ........MEEPRHSKRPRFLAPNQASGGPPTEPGCSRVDRED----...--PVDPVQPSKPTAYVKPMRREPPARAEPAPP.AGRG...QRG..GGSWRA--GR.GRGSGAGLLRALGER---......---VGP.......GMYlVHLNDHGEPGYQGQLEARQTPAFSFTEAAPMPGIVQE....GPSPHAAQPEVGLQEPPPAPGPVAVARHTMLAPSPSLSFRPPGGSSTLRIVQTSNGTIVQSVPVFPAHSAY..............................
H2NK02_PONAB/1-221                  ........MEEPRPSKRLRTMAPNQASGGPPREPGCSVADPEDSVEA...DGPTQPAQPAKPIAYLTPFRWQPPAPTESARP.AERG...WRP..GGSRWP--GR.GRGRGGGPRRDAGPRQGA......ERLLGP.......DLH.IQLDHYGEPGHQGEQEITETAAFSLSETAPVPVTVQE....GPGLEVAQPELGLQEPPPASGPQAVARQPMLTLYPCIGFRALGGSAALQIIQTPYSTYVQGVPVFVTDIAY..............................
A0A2I3H0L3_NOMLE/1-221              ........MEEPRPSKRLRSMATDQASGGPPPEPGCSVVDPEDSVEA...DGPAQPAQPAKPTAYVKPFRWQPPAGTEPARP.AERG...RRR..GGSRRP--GR.GRGRGGGPRRDAGQRQGA......ERLPGP.......DLH.IQLDHHGEPGHQVELEIWETEASSLSETAPVPGTVQE....GHGPDVAQPELGLQEPPPAPGPQAVAGQPMLTVYPCIGFRALGGSAALQVIQTPHGTYVQGVPVFVADIAY..............................
A0A096NRJ7_PAPAN/1-223              ........MEEPRRSKRLRYMTPNQ-SGGRPTEPFCSVVDPEDSVEVqstESHAEPAQPTKPIAYVKPFRWEPPARTESAPP.AERG...RRR..GGSRLA--GR.GRGRGHGARRNAGQRQRA......ERLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFPETAPVPGTVQE....GPGPDMAHPEVGHQEPPPASGPEANAREPMLMIYPCIGFRALGGSAVLQVIQTANGTYVQGIPVFVANIAY..............................
F7F3A7_CALJA/96-169                 ......av---------------------------------------...--------------------------------.----...---..----------.------------------......------.......---.-------------------------------RRTVLE....GPVPPEALPRVGPQGLPPVSGPEAVAWQPTL-----IGFMPLGDSSVLGVTHSSMGTYVHGVPVFMGHIT-h.............................
H2NKF9_PONAB/1-203                  ........------------------SGGPPREPGCSVVDPEDSVEA...DEPAHPAQPAKPIAYVTPFRWQPPAPTESARP.AERG...RRR..GGSRSA--GR.GRGRGGGPRRDAGPRQGA......QRLMGS.......DVH.IQLDHHGEPGHQGEPEIRETAAFSLSETGHLPGTVQE....GPGPDVAPPELGLQEPPPASEPQAVAGQPTLTLYHCVGFRALGDPAVLQVIETPHGTYVQGVPVFFTDIA-c.............................
A0A2K5IV36_COLAP/1-222              ........MEEPRRSKRLRYMAPNQASGGHPTEPGCSVVDPEDSLEV...DGPAEPAQPSKPIAYVKPLRREPPARTESAPP.AQRG...RRR..GGSRQAGRGR.GRGRGRGPRRDAGQRQRA......ERLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFRETAPVPRTV-E....GPGPEVAQPEVGHQEPPPVFGPEAVAREPMLTLYPCIGFRALGGSDVLQVIQTPSGTYVQGVPVFVANIAY..............................
A0A2K5KTC7_CERAT/1-223              ........MEEPRLSKRLRSMASNQASGGRPTEPGCSIVDREDSVEA...DGPAEPAQPAKRIAYVKPLRREPPACTELAPP.AERG...QRR..GGSRRVGRGR.GRGRGSGPRRDAGQGQGT......EHLLGP.......DMD.IQLHHHGEPGHQGEPEIRQTAAFSFPETAPVSGTVQE....GPGPDVAHPEVGRQEPPPASEPETINGQPMLTLYPCIGFRALGDSAVLQVIQTPNGTYVQGIPVFVTNIAY..............................
A0A2K5IU67_COLAP/1-223              ........MEEPRHSKRFRSMAPNQASGGCPTEPGCSIVDCEDSLEA...DGPAKPAQPAKQIAYVKPLRREPPAHTELASP.AERG...RRR..GGSRRAGRGR.GRGRGGGPRRVAGQRQRA......ERLLEL.......YMD.IQLHHHGRPGHQGEPEIRQTAAFSFPETAPIPGTVQE....GPDPDMAHPEVGRQEPPRVSEPEAVNGQPMLTLYPCIGFRALGGSDVLQVIQTPNCTYVQGIPVFVADIAY..............................
PR20A_HUMAN/1-221                   ........MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEA...DGPAQPAQPAKPIAYVKPFRRQPPARPESPPP.AERG...RRR..GGSRRP--GR.GRGRRAGPRGDAGQRQGA......EGLMAP.......DVH.IQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQE....GPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY..............................
D3ZF00_RAT/8-158                    sqlpsets---------------HQDSDEGPREQSDPCVEHKDPVEV...DE---SDGPAKPIAYVRPRRCEPTAPAEAAEDhADRR...NHQ..ERSAYPGRQR.WRQRP-WQRAEIGNHSQAafqvwrEASEGR.......VPQ.IYINHSEGPH---------------------------....-----------------------------------------------------------------------ldlrtgadmsvyptftpigpvpaemaqwpp
F6W2Q4_MACMU/1-219                  ........MEEPRRSKRLRSMDPNQ--GGCPTEPGCSIVDREDSVEA...DGPAEPAQPAKRIAYVKPLRREPPACTELAPP.TERG...QRR..GGSRRV--GR.GRGRGSGPRRDAGQGQGA......EHLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFPETAPVPGTVQE....GPGPDVAHPEVGRQEPPPASEPEAINGQPMLTLYPCIGFRALGGSAVLQVIQTPNGTYVQGIPVFVADIAW..............................
A0A0D9R7U8_CHLSB/1-208              ........MEEPRRSKRLRSMAPNQASGGPPTEPGCSSMDHED----...--PVEPVQPAKPTAYVKPMRWEPPARAELARP.AGRG...RRR..GGSWWA--GR.ARGSGALLHRVPGQR---......---EGP.......DVY.IHLNYHGEPGHQGEPEAGQNPAFSFTEAAPMPGIVQE....GPGPHAAQPEVGFQEPPPA-GPVAVARQPMLALYPCIGFRPLGGSAFLRIMQTSSGTYVHRVPVFLAHIA-h.............................
A0A2I3SJ84_PANTR/1-210              ........MGEPRHSKRPRFLAPNQASGGPPTDPGCSGVDRED----...--PVDPVQLAKPTAYVKPMRREPPARAQPAPP.AGRG...QRG..GGSWRA--GR.GRGSGAGLLGALGER---......---VGP.......GMYlVHLNDHGELGYQGQLEVRQTPAFSFTEAALMPGIVQE....GPSPHAAQPEVGLQEPPPAPGPVAVARQTMLAPSPSLSFRPPGGSSTLRIVQTSNGTIVQSVPVFPAHSA-h.............................
A0A2I3HGU6_NOMLE/1-221              ........MEEPRPSKRLRSMATDQASGGPPPEPGCSAVDPEDSVEA...DGPAQPTQPAKPTAYVKPFRWQPPAGTEPARP.AERG...RRR..GGSRRP--GR.GGGRGGGPRRDAGQRQGA......ERLPGP.......DLH.IQLDHHGEPGHQGELEIWETEASSLSETAPVPGTVQE....GPGPDVAQPELGLQEPPPAPGPQAVAGQPMLTVYPCIGFRALGGSAALQVIQTPHGTYVQGVPVFVTDIAY..............................
A0A2K5KWM1_CERAT/1-147              ........------------------SSGHPTEPSCSVVDPEDSLEV...DAPAEAAQPAKPIAYVKPLRREPPACTESAPP.AERG...RRR..GGSPRA--GR.GRGRGRGPRREAGQRQGA......ERLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFPGTAPVPRTV-E....GPGPEGAQPEVGHQEP-------------------------------------------------------..............................
PR20E_HUMAN/1-221                   ........MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEA...DGPAQPAQPAKPIAYVKPFRRQPPARPESPPP.AERG...RRR..GGSRRP--GR.GRGRRAGPRGDAGQRQGA......EGLMAP.......DVH.IQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQE....GPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY..............................
A0A091E1W6_FUKDA/78-302             ........MEEQRPRKRPRTVAPDPASEGDPRESDHPNVEFEDLGEA...DGPAESGQPKKPIAYVNPMRFEVPVRTEPAGP.TQRGriqRRP..QQAERAHTQGqGRRAGRHRHWETDSREQL......ERSQEP.......-VH.GQLVGQEEPGHRVDPEASWTSAFSFI-TAS---TVREdellGRSSHSNQLAGAIREPPPVSGYWAVTGRQISAIYPYIGFIPLFGSS-LYFVETPFGTHVFGVPVFFTNIA-h.............................
G3RNF4_GORGO/1-156                  ........MEEPRPSKRLRSTAPNQASGGPPPEPGCCVADPEDSVEA...DGPAQPAQPAKPIAYVTPFRWQTPARTESPRP.AERG...RRR..GGSRRP--GR.GRGRRAGPRGDAGQRQGA......ERLTGP.......DVH.IQLDHHGEPGHQGEPEITETAAFSLSETGPLPGTVQG....GPGPDV-----------------------------------------------------------------..............................
G7PVG9_MACFA/1-223                  ........MEEPRRSKRLRSMDPNQASGGRPTEPGCSIMDREASVEA...DGPAEPAQPAKRIAYVKPLRREPPACTELAPP.AERG...QRQ..GGSRRVGRGR.GRGRGSGPRRDAGQRQGA......EHLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFPETAPVPGTVQE....GPGPDVAHPEVGRQEPPPASEPEAINGQPMLTLYPCIGFRALGGSAVLQVIQTPNGTYVQGIPVFVADIVW..............................
A0A2I3MYZ3_PAPAN/1-214              ........----------RSMASNQASGGRPTEPFCSVVDPEDSVEVqstESHAEPVQPTKPIAYVKPFRWEPPARIESAPP.AERG...RRR..GGSRLA--GR.GRGRGRGARRNAGQRQGA......ERLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTSAFSFPETAPVPGTVQE....GPGPDMAHPEVGHQEPPPASGPEAIAREPMLMIYPCIGFRALGGSAVLQVIQTANGTYVQGIPVFVANIAY..............................
PR20B_HUMAN/1-221                   ........MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEA...DGPAQPAQPAKPIAYVKPFRRQPPARPESPPP.AERG...RRR..GGSRRP--GR.GRGRRAGPRGDAGQRQGA......EGLMAP.......DVH.IQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQE....GPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY..............................
F7F3A7_CALJA/1-100                  ........MEEPRRSKRLRSMDSNQASGGPSTEPGHSVVDREDPVET...DGPAEPAQPTKPTAYVKPFRWEPAAHTQPTRP.AERG...RRRgrGGSQRAGRGG.GRGRGAVR----------......------.......---.-------------------------------------....-----------------------------------------------------------------------rt............................
G1U7J3_RABIT/8-100                  ...lgqgt--------------PLQSSGGPSQEPGHSGVRQEDPTEA...DGSPGPAQPTKPVAYVKPMSIQTRAYARTAPP.AGRG...QRR..GSRERPGRGR.GRGKA-------------......------.......---.-------------------------------------....-----------------------------------------------------------------------gprgqqgwg.....................
S9XAG5_CAMFR/1-197                  .......m--EERPSKRFCATAPG--HGGRPWQEGRPDAEDGAPVGA...ASPALPGRAPKPFAYVKPMRRETSTSVEPARP.AQRGr.gRHR..GNSQRT--GR.GGGRGT------------......----GP.......HPH.VELDNRDEPGHPVEPEARRTPSLPFTQAAG-QGYRLQ....GPGPLGDLLGVRHQGLPNAYGYWDLQGSRPSAICPYVGFVP-SGSA-LIVMQMPFGTYLYAVP--------prsa..........................
PR20D_HUMAN/1-221                   ........MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEA...DGPAQPAQPAKPIAYVKPFRRQPPARPESPPP.AERG...RRR..GGSRRP--GR.GRGRRAGPRGDAGQRQGA......EGLMAP.......DVH.IQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQE....GPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY..............................
PR20C_HUMAN/1-221                   ........MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEA...DGPAQPAQPAKPIAYVKPFRRQPPARPESPPP.AERG...RRR..GGSRRP--GR.GRGRRAGPRGDAGQRQGA......EGLMAP.......DVH.IQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQE....GPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY..............................
A0A2K5M8K6_CERAT/1-224              ........MEGPRPSKRLRYMAPNQASGGRPTEPFCSVVDPEDSVEVqstESHAEPLQPAKPIAYVKPLRWEPPARTESAPP.AERG...RRR..GGSRLA--GR.GRGRGRGARRNAGQRQGA......EGLLGP.......DMH.IQLHHHGEPGHQGEPEIRQTAAFSFPETAPVPGTVQE....GPGPDVAHPEVGRQEPLPASGPEANALEPMLTNYPCIGFRALGGSADLQVIQTANGTYVQGIPVFVANIA-c.............................
H2NKF5_PONAB/1-203                  ........------------------SGGPPREPGCSAVDREDSVET...DGPEQPAQPAKPIAYVTPFRWQPPAPTESARP.AERG...RRR..GGSRPA--GR.GRGRGGGPRRDAGPRRGA......QRLMGS.......DVH.IQLDHHGEPGHQGEQEIRETAAFSLSETGHLPGTAQE....GPGPDVAPPELGLQEPPPASGPQAVAGQPTLTLYPCVGFRALGDPAVLQVIQTPHGTYVKGVPVFFADIA-c.............................
#=GC seq_cons                       ........MEEPR.SKRhRsMAPNQASGGsPsEPGCSlVDsEDSVEs...DGPApPAQPAKPIAYVKPhRhpPPApsEsAsP.AERG...RRR..GGSRRs..GR.GRGRGuGsRt-AGQRQtA......EtLhGP.......DhH.IQLcHHGEPGHQGEPEIppTuAFShsETAPhPGTVQE....GPGP-sApPElGhQEPPPAsGPpAlshpPhLslYPCIGFRALGsSAsLQVIQTspGTYVQGlPVFhssIA...............................
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