#=GF ID PUMA
#=GF AC PF15826.5
#=GF DE Bcl-2-binding component 3, p53 upregulated modulator of apoptosis
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE Jackhmmer:Q9BXH1
#=GF GA 25.00 25.00;
#=GF TC 25.10 27.10;
#=GF NC 24.70 24.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 11463392
#=GF RT PUMA, a novel proapoptotic gene, is induced by p53.
#=GF RA Nakano K, Vousden KH;
#=GF RL Mol Cell. 2001;7:683-694.
#=GF DR INTERPRO; IPR031661;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC PUMA (p53 upregulated modulator of apoptosis) is a family of
#=GF CC eukaryotic proteins that are a target for activation by p53. The
#=GF CC proteins contain BH3 domains and are induced in cells after p53
#=GF CC activation. They bind to Bcl-2, localise to the mitochondria to
#=GF CC induce cytochrome c release, and activate the rapid induction of
#=GF CC apoptosis [1].
#=GF SQ 37
#=GS H0XQ00_OTOGA/2-193 AC H0XQ00.1
#=GS A0A2I3N2Z9_PAPAN/7-131 AC A0A2I3N2Z9.1
#=GS A0A1B0GR88_MOUSE/2-91 AC A0A1B0GR88.1
#=GS A0A2I3RIG5_PANTR/2-193 AC A0A2I3RIG5.1
#=GS A0A1L8F8S1_XENLA/2-199 AC A0A1L8F8S1.1
#=GS A0A1S3AJ13_ERIEU/2-193 AC A0A1S3AJ13.1
#=GS S7MGL3_MYOBR/2-197 AC S7MGL3.1
#=GS F7CQN5_HORSE/1-115 AC F7CQN5.1
#=GS L5KMM8_PTEAL/2-136 AC L5KMM8.1
#=GS A0A2I3HWI8_NOMLE/6-107 AC A0A2I3HWI8.1
#=GS BBC3_RAT/2-193 AC Q80ZG6.1
#=GS G5AV07_HETGA/2-131 AC G5AV07.1
#=GS L9L8D9_TUPCH/45-173 AC L9L8D9.1
#=GS A0A1S3GGN4_DIPOR/60-99 AC A0A1S3GGN4.1
#=GS D3Z2M5_MOUSE/2-128 AC D3Z2M5.1
#=GS A0A0D9S2H2_CHLSB/8-199 AC A0A0D9S2H2.1
#=GS A0A1U8CYM6_MESAU/18-209 AC A0A1U8CYM6.1
#=GS G1LNV7_AILME/7-152 AC G1LNV7.1
#=GS H2NZD3_PONAB/2-193 AC H2NZD3.1
#=GS F7FFP6_MACMU/7-131 AC F7FFP6.1
#=GS A0A1U7R5N5_MESAU/2-193 AC A0A1U7R5N5.1
#=GS K7E5Y2_MONDO/263-465 AC K7E5Y2.1
#=GS A0A2I3RGH5_PANTR/7-131 AC A0A2I3RGH5.1
#=GS M3Y0R3_MUSPF/8-201 AC M3Y0R3.1
#=GS J9NTK9_CANLF/2-193 AC J9NTK9.1
#=GS L5LCU5_MYODS/30-181 AC L5LCU5.1
#=GS F6RCL1_CALJA/9-131 AC F6RCL1.1
#=GS G3T2N1_LOXAF/2-186 AC G3T2N1.1
#=GS A0A2G9RZQ5_LITCT/25-216 AC A0A2G9RZQ5.1
#=GS BBC3_HUMAN/2-193 AC Q9BXH1.1
#=GS BBC3_HUMAN/2-193 DR PDB; 4BPK D; 1-20;
#=GS BBC3_HUMAN/2-193 DR PDB; 4HNJ C; 302-323;
#=GS BBC3_HUMAN/2-193 DR PDB; 5UUL B; 1-23;
#=GS BBC3_HUMAN/2-193 DR PDB; 2M04 B; 68-92;
#=GS BBC3_HUMAN/2-193 DR PDB; 4BPJ D; 90-106;
#=GS BBC3_HUMAN/2-193 DR PDB; 4BPI B; 87-105;
#=GS BBC3_HUMAN/2-193 DR PDB; 4BPK C; 1-20;
#=GS BBC3_MOUSE/2-193 AC Q99ML1.1
#=GS BBC3_MOUSE/2-193 DR PDB; 2VOF B; 131-153;
#=GS BBC3_MOUSE/2-193 DR PDB; 2ROC B; 130-155;
#=GS BBC3_MOUSE/2-193 DR PDB; 2VOF D; 132-153;
#=GS L9L8D9_TUPCH/2-53 AC L9L8D9.1
#=GS A0A1A6GEG9_NEOLE/1-107 AC A0A1A6GEG9.1
#=GS A0A2K5P2T8_CERAT/8-131 AC A0A2K5P2T8.1
#=GS A0A1S3GGN4_DIPOR/18-63 AC A0A1S3GGN4.1
#=GS F7GL32_MONDO/2-204 AC F7GL32.1
#=GS F1RM01_PIG/2-193 AC F1RM01.3
H0XQ00_OTOGA/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.TLGGPR.WP.GGPRSRPRGPR....-..LDGPQ......PS..LLP..........AEQ.HLESPVpst....pgalAGGPTQAAPEVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
A0A2I3N2Z9_PAPAN/7-131 ..saracpcqvprassatwv---------------------------------------------.----------------..-...---------.------.--.---------PC....Q..ICGPQ......PS..LLL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
A0A1B0GR88_MOUSE/2-91 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLMPSAVSCSLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGHRSRPRGPR....P..-----......--..---..........---.------...........---------------.....-----------------------------------.-----------------------------d............................
A0A2I3RIG5_PANTR/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAA.APAAPTLLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
A0A1L8F8S1_XENLA/2-199 ....................ARPLNDGKPSEPVGNIQVETSHAFPAG--VAETPCGGICEQSLPS.--SHPSTTNHSQPSFC..QinhCQINNCQIS.LGTESNcQE.SGPSSAPCGNS....HchFSGCYnt.gesTA..LSLth......slSE-.--NSGMevnvrildqddFAGDIQGGAMLAG-E.....EDIEREIAMRLRRIGDQMNELYMQRRVGGERHWWG.PLRWHL-TQFISEIL--------------aalynp.......................
A0A1S3AJ13_ERIEU/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLSRLVPSTVSCGLCEPGLPT.APATPALLPA--AYLC..A...PTAPPAVTAaTLGGPR.WP.GGPRSRPRSPR....P..-DGPQ......PS..LSP..........VEQ.HLVSPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEEQ-RHR.PSPWRVLYNLMMGLLPLPRGRGAPEMEPN.............................
S7MGL3_MYOBR/2-197 ....................ARARQEGSSPEPVEGLARDGPRPFPLSRLVPSAVSCGLCEPGLPP.APATPARLPA--AYLC..A...PTALPAVTA.ALGAPR.WP.GGPRSRPRGPH....P..-NGPQ......PDgpLTPwc......paAPS.HRHSAAgadc...pgfpPAPPCPWSPGRLGER.....NFS-KLSSLAVR---QDGTRFQDQGLRQEEQQRHG.PSPWRVLYNLILGLLPLPRGRGAPEMEPN.............................
F7CQN5_HORSE/1-115 ...................a---------------------------------------------.----------------..-...---------.------.--.-GQSSRPRGPA....P..-RGPQ......PS..LLP..........AEQ.HLESPVpsa....pgalEGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGRAAPEMEPN.............................
L5KMM8_PTEAL/2-136 ....................ARARQEGSSPEPVEGLARDGPRPFPLSRLVPSAVSCGLCEPGLPA.APAAPALLPA--AFLC..A...PTAPPTATA.ALGGPR.WP.AGPRSRPRGPR....P..DETRA......AA..TPP..........C--.TLEGPV...........---------------.....-----------------------------------.-----------------------------rshhgtaaltqgpwdprdgaqlgactrpa
A0A2I3HWI8_NOMLE/6-107 gsaracpcqvprassvtwvp---------------------------------------------.----------------..-...---------.------.--.-----------....-..-----......--..---..........---.-----Cq........icAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
BBC3_RAT/2-193 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLMPSAVSCGLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGHRSRPRGPR....P..-DGPQ......PS..LSP..........AQQ.HLESPVpsa....pealAGGPTQAAPGVRVEE.....EEWAREIGAQLRRMADDLNAQYERR-RQEEQHRHR.PSPWRVMYNLFMGLLPLPRDPGAPEMEPN.............................
G5AV07_HETGA/2-131 ....................ARARQEGSSPEPVD-----GPRPFPLGRLVPSAVSCGLCEPGLPA.APSTPALLPA--AYLC..A...PTAPPTLTA.ALGGPR.WP.GGPRTRPRGPR....P..DETRG......AA..ATPpvtl..egavQSH.HGTPAL...........TQGP-----------.....-----------------------------------.-----------------------------qsprdgaqlgacirp..............
L9L8D9_TUPCH/45-173 .............paapapp---------------------------------------------.----------------..-...---------.-LGGSR.WP.GGPRSRPRGPR....P..-DGPQ......PS..ISP..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLILGLLPLPRGHRAPEMEPN.............................
A0A1S3GGN4_DIPOR/60-99 ..................lp---------------------------------------------.----------------..-...---------.------.--.-----------....-..-----......--..---..........---.------...........---------------.....--------------------------RQEEQQRHR.PSPWRVLYNIIMGLLPLPRGPGAPQMEPN.............................
D3Z2M5_MOUSE/2-128 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLMPSAVSCSLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGHRSRPRGPR....P..-DGPQ......PS..LSP..........AQQ.HLESPVpsa....pealAGGPTQAAPGVR---.....-----------------------------------.-----------------------------v............................
A0A0D9S2H2_CHLSB/8-199 ....................ARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAQEIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
A0A1U8CYM6_MESAU/18-209 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLVPSAVSCGLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSP..........AQQ.HLESPVpsa....pealAGGPTQAAPGVRGEE.....EEWAREIGAQLRRMADDLNAQYERR-RQEEQHRHR.PSPWRVMYNLFMGLLPLPRDPGAPEMEPN.............................
G1LNV7_AILME/7-152 dpisrpqaqvwklrprcvtg---------------------------------------------.----------------..-...---------.--GKHR.LR.GGSEGGGAGRHlpnpS..PPGPQ......PS..LSP..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEERQRHR.PSPWRVLYNLIMGLLPLPRGRGAPEMEPN.............................
H2NZD3_PONAB/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
F7FFP6_MACMU/7-131 ..saracpcqvprassatwv---------------------------------------------.----------------..-...---------.------.--.---------PC....Q..ICGPQ......PS..LLL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
A0A1U7R5N5_MESAU/2-193 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLVPSAVSCGLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSP..........AQQ.HLESPVpsa....pealAGGPTQAAPGVRGEE.....EEWAREIGAQLRRMADDLNAQYERR-RQEEQHRHR.PSPWRVMYNLFMGLLPLPRDPGAPEMEPN.............................
K7E5Y2_MONDO/263-465 ....................ARAQQDGSSPEPVEGLPRESPRTFPLGRLMPSAVSCSLCEAGLNP.--SGDSMCPAPGPALA..P...SSLLPLAYF.CTRQPR.AY.GGPRWARAARS....P..AAGNQgqsgslPS..LGPrsaqeeggqeGEP.QGASPM...........SGGP----PGVLGPEhgdqgEQQDREIGAQLRRMADDLNALYEQRRREEEQRRHL.-SPWRLLYNLISGLLAPQRRNRMPDVEPN.............................
A0A2I3RGH5_PANTR/7-131 ..saqacpcqvpraasatwv---------------------------------------------.----------------..-...---------.------.--.---------PC....Q..ICGPQ......PS..LSL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
M3Y0R3_MUSPF/8-201 ....................ARARQEGSSPEPVEGLSRDGPRPFPLSRLVPSAVSCGLWESDCSP.RVAAHGLFRAGAAAVS..Q...PPPPPVWVS.LTSQRT.IV.GGSVGRARGLL....-..FPGPQ......PS..LSP..........AEP.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGRGAPEMEPN.............................
J9NTK9_CANLF/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLSRLVPSAVSCGLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSP..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGRGAPEMEPN.............................
L5LCU5_MYODS/30-181 ....................ARARQEGSSPEPVEGLARDGPRPFPLSRLVPSAVSCGLCEPGLPP.APATPALLPA--AYLC..A...PTALPAVTA.ALGAPR.WP.GGPRSRPRGPH....P..-NGPQ......PS..LSP..........AEQhHLESPVpsa....pgalAGGPTQAAPGIRGEE.....EQWARERLAHTSMM---------------------.-----------------------------resligcl.....................
F6RCL1_CALJA/9-131 ..wacpcqvprasssvwvpc---------------------------------------------.----------------..-...---------.------.--.-----------....Q..MCGPQ......PS..LSL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEEQPQHR.PSPWRVLYNLIMGLLPFPRGHRAPEMEPN.............................
G3T2N1_LOXAF/2-186 ....................ARARQEGSSPEPVEGLARESPRPFPLGSLVPSAVSCGLCEPGL-P.RVAGPRLLPGPRTQLF..-...PSPSPVWVS.DLSGLQ.LErGGAEWEDRAPR....P..LSGPQ......PS..LSP..........AEQ.HLESPV...........---PTQAAPGVRGED.....EQWAREIGAQFRRKADDLYALYERSVRQEEQHRHR.PSPWRVLYNLIMGLLPLPRDHGAPEMEPN.............................
A0A2G9RZQ5_LITCT/25-216 ....................ARALHDGSTSERVGNIQSDAGRTFPPDVSACAGSSSRICEQNLPVsHPAQPSMCQRCLPLCQnhP...QDRLEMVNS.CESGPS.SP.ACEQRHCSYPE....S..FSTGE......PT..AYGl........rHTT.HEHSNMgtev...eeshQDDP-QAGLALAG-D.....VPVEREIALRLRRIGDQMNERYLRR-RQVAQRQWWgPLRWH-LTQMISEILA-------------alynpl.......................
BBC3_HUMAN/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAA.APAAPTLLPA--AYLC..A...PTAPPAVTA.ALGGSR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
#=GR BBC3_HUMAN/2-193 SS ....................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX--XXXX..X...XXXXXXXXX.XXXXXX.XX.XXXXXXXXXXX....X..-XXXX......XX..XXX..........XXX.XXXXXXXXX....XXXXXXXXXXXXXXXXXXX.....XSHHHHHHHHHHHHHHHHHHTTXXX-XXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.............................
BBC3_MOUSE/2-193 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLMPSAVSCSLCEPGLPA.APAAPALLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGHRSRPRGPR....P..-DGPQ......PS..LSP..........AQQ.HLESPVpsa....pealAGGPTQAAPGVRVEE.....EEWAREIGAQLRRMADDLNAQYERR-RQEEQHRHR.PSPWRVMYNLFMGLLPLPRDPGAPEMEPN.............................
#=GR BBC3_MOUSE/2-193 SS ....................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX--XXXX..X...XXXXXXXXX.XXXXXX.XX.XXXXXXXXXXX....X..-XXXX......XX..XXX..........XXX.XXXXXXXXX....XXXXXXXXXXXXXXXXXXX.....XHHHHHHHHHHHHHHHHHHHHCHTX-XXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.............................
L9L8D9_TUPCH/2-53 ....................ARARQEGSSPEPVEGLARDGPRPFPLGRLMPSAVSCGLCEPGLPA.APA-------------..-...---------.------.--.-----------....-..-----......--..---..........---.------...........---------------.....-----------------------------------.-----------------------------pplg.........................
A0A1A6GEG9_NEOLE/1-107 ................msar---------------------------------------------.----------------..-...---------.------.--.-----------....-..-GGPQ......PS..LSP..........AQQ.HLESPVpsa....pealAGGPTQAAPGVRGEE.....EEWAREIGAQLRRMADDLNAQYERR-RQEEQHRHR.PSPWRVMYNLFMGLLPLPRDPGAPEMEPN.............................
A0A2K5P2T8_CERAT/8-131 .aracpcqvpraasatwvlc---------------------------------------------.----------------..-...---------.------.--.-----------....Q..ICGPQ......PS..LLL..........AEQ.HLESPVpsa....pgalAGGPTQAAPGVRGEE.....EQWAREIGAQLRRMADDLNAQYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGHRAPEMEPN.............................
A0A1S3GGN4_DIPOR/18-63 ....................ARARQEGSSPEPVEGLARDSPRPFPLGRLVPSAVSCGLCEPGLP-.----------------..-...---------.------.--.-----------....-..-----......--..---..........---.------...........---------------.....-----------------------------------.-----------------------------rq...........................
F7GL32_MONDO/2-204 ....................ARAQQDGSSPEPVEGLPRESPRTFPLGRLMPSAVSCSLCEAGLNP.--SGDSMCPAPGPALA..P...SSLLPLAYF.CTRQPR.AY.GGPRWARAARS....P..AAGNQgqsgslPS..LGPrsaqeeggqeGEP.QGASPM...........SGGP----PGVLGPEhgdqgEQQDREIGAQLRRMADDLNALYEQRRREEEQRRHL.-SPWRLLYNLISGLLAPQRRNRMPDVEPN.............................
F1RM01_PIG/2-193 ....................ARARQEGSSPEPVEGLARDGPRPFPLSRLVPSAVSCGLCEPGLPA.APAAPTLLPA--AYLC..A...PTAPPAVTA.ALGGPR.WP.GGPRSRPRGPR....P..-DGPQ......PS..LSP..........AEQ.HLESPVpsa....pgalAGGPTQAAPGIRGEE.....EQWAREIGAQLRRMADDLNALYERR-RQEEQQRHR.PSPWRVLYNLIMGLLPLPRGRGAPEMEPN.............................
#=GC SS_cons ....................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX--XXXX..X...XXXXXXXXX.XXXXXX.XX.XXXXXXXXXXX....X..-XXXX......XX..XXX..........XXX.XXXXXXXXX....XXXXXXXXXXXXXXXXXXX.....XCHHHHHHHHHHHHHHHHHHCCHTX-XXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.............................
#=GC seq_cons ....................ARApQ-GSSPEPVEGLsR-uPRsFPLuRLhPSAVSCuLCEsGLss...utsshh.t..s.ht......ss..shhh..hhutsp.h..GG.cscspuPp....s...sGPQ......PS..Lo...........ApQ.HLESPVPSA....PtALAGGPTQAAPGVRGEE.....EpWAREIGAQLRRMADDLNA.YERR.RQEEQpRHR.PSPWRVLYNLIMGLLPLPRs.tAPEMEPN.............................
//
