#=GF ID   Pfk_N
#=GF AC   PF18468.5
#=GF DE   Phosphofructokinase N-terminal domain yeast
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF02430
#=GF GA   26.80 26.80;
#=GF TC   26.90 26.90;
#=GF NC   26.30 26.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Phosphofructokinase
#=GF CL   CL0240
#=GF RN   [1]
#=GF RM   20833871
#=GF RT   Molecular architecture and structural basis of allosteric
#=GF RT   regulation of eukaryotic phosphofructokinases.
#=GF RA   Strater N, Marek S, Kuettner EB, Kloos M, Keim A, Bruser A,
#=GF RA   Kirchberger J, Schoneberg T;
#=GF RL   FASEB J. 2011;25:89-98.
#=GF DR   INTERPRO; IPR040712;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a phosphofructokinase (Pfk) N-terminal domain found in
#=GF CC   yeast ATP-dependent 6-phosphofructokinase subunit alpha.
#=GF CC   ATP-dependent 6-phosphofructokinases (Pfks, EC 2.7.1.11)
#=GF CC   catalyze the phosphorylation of fructose 6-phosphate (F-6-P) to
#=GF CC   fructose 1,6-bisphosphate, a key control step of glycolysis in
#=GF CC   most organisms. The N-terminal domain contains the active site
#=GF CC   and is related to glyoxalase I (E.C. 4.4.1.5) [1].
#=GF SQ   92
#=GS A0A061ANW7_CYBFA/4-94     AC A0A061ANW7.1
#=GS A0A1Q2YG84_9ASCO/18-121   AC A0A1Q2YG84.1
#=GS C4Y0S9_CLAL4/4-108        AC C4Y0S9.1
#=GS A0A4P6XDG7_9ASCO/4-103    AC A0A4P6XDG7.1
#=GS A0A8H8A6H9_9ASCO/200-266  AC A0A8H8A6H9.1
#=GS A0A1G4MJ32_LACFM/7-100    AC A0A1G4MJ32.1
#=GS A0A7H9B316_ZYGMR/8-101    AC A0A7H9B316.1
#=GS B6JW37_SCHJY/7-80         AC B6JW37.1
#=GS G8JQL6_ERECY/7-100        AC G8JQL6.1
#=GS A3LNQ5_PICST/8-113        AC A3LNQ5.2
#=GS A0A1E3PPM6_9ASCO/9-103    AC A0A1E3PPM6.1
#=GS A0A5E8BYN4_9ASCO/12-97    AC A0A5E8BYN4.1
#=GS A0A1E4SYJ4_9ASCO/11-113   AC A0A1E4SYJ4.1
#=GS A0A2H0ZIL9_CANAR/4-103    AC A0A2H0ZIL9.1
#=GS G0W9W5_NAUDC/8-101        AC G0W9W5.1
#=GS A0A376B6M1_9ASCO/26-119   AC A0A376B6M1.1
#=GS A0A8J5USS8_9ASCO/11-116   AC A0A8J5USS8.1
#=GS A0A1S7HX15_9SACH/18-111   AC A0A1S7HX15.1
#=GS A0A7H9HM78_9SACH/9-102    AC A0A7H9HM78.1
#=GS A5E352_LODEL/8-112        AC A5E352.1
#=GS J7SAR7_KAZNA/8-101        AC J7SAR7.1
#=GS A0A4C2DZF5_9SACH/9-102    AC A0A4C2DZF5.1
#=GS PFKA1_KOMPG/7-112         AC Q92448.2
#=GS Q758H0_ASHGO/7-100        AC Q758H0.1
#=GS A5DIC5_PICGU/5-106        AC A5DIC5.2
#=GS A0A8H7L8B7_9ASCO/4-103    AC A0A8H7L8B7.1
#=GS K0KJI7_WICCF/4-93         AC K0KJI7.1
#=GS A0A8H6BRQ2_CANAX/9-114    AC A0A8H6BRQ2.1
#=GS A0A1G4J735_9SACH/9-102    AC A0A1G4J735.1
#=GS A0A1X7R9N1_9SACH/8-101    AC A0A1X7R9N1.1
#=GS A0A1S7HE37_9SACH/18-111   AC A0A1S7HE37.1
#=GS A0A1E3PPA8_9ASCO/5-80     AC A0A1E3PPA8.1
#=GS C5MJ51_CANTT/8-113        AC C5MJ51.1
#=GS A0A1L0D5I0_9ASCO/4-109    AC A0A1L0D5I0.1
#=GS A0A0C7N118_9SACH/7-100    AC A0A0C7N118.1
#=GS G8BNW7_TETPH/8-101        AC G8BNW7.1
#=GS PFKA_YARLI/3-65           AC P59680.2
#=GS A0A448YF46_BRENA/5-107    AC A0A448YF46.1
#=GS A0A1E4RL19_9ASCO/6-111    AC A0A1E4RL19.1
#=GS W1QIH3_OGAPD/5-89         AC W1QIH3.1
#=GS A0A421JQ79_9ASCO/2-107    AC A0A421JQ79.1
#=GS A0A1E3QIB2_9ASCO/5-99     AC A0A1E3QIB2.1
#=GS G0VGB3_NAUCC/8-101        AC G0VGB3.1
#=GS A0A167DNJ0_9ASCO/6-92     AC A0A167DNJ0.1
#=GS G8YT39_PICSO/8-113        AC G8YT39.1
#=GS G3B045_CANTC/4-100        AC G3B045.1
#=GS A0A642UU77_DIURU/3-109    AC A0A642UU77.1
#=GS A0A0E9NS83_SAICN/12-85    AC A0A0E9NS83.1
#=GS Q6BH76_DEBHA/9-110        AC Q6BH76.2
#=GS I2K2U6_DEKBR/9-111        AC I2K2U6.1
#=GS PFKA_SCHPO/7-77           AC O42938.1
#=GS A0A7D9GWT9_DEKBR/9-111    AC A0A7D9GWT9.1
#=GS J8Q4Q3_SACAR/8-101        AC J8Q4Q3.1
#=GS A0A512U890_9ASCO/4-103    AC A0A512U890.1
#=GS A0A1D2VPR3_9ASCO/7-103    AC A0A1D2VPR3.1
#=GS A0A4T0WZD1_9ASCO/22-126   AC A0A4T0WZD1.1
#=GS M7PLJ6_PNEMU/11-102       AC M7PLJ6.1
#=GS A0A1E4TTN8_PACTA/9-108    AC A0A1E4TTN8.1
#=GS C5DCN7_LACTC/7-99         AC C5DCN7.1
#=GS W7HWB6_9PEZI/14-90        AC W7HWB6.1
#=GS Q6FTX6_CANGA/8-101        AC Q6FTX6.1
#=GS Q5AK53_CANAL/9-114        AC Q5AK53.1
#=GS A0A4P9ZF45_9ASCO/4-106    AC A0A4P9ZF45.1
#=GS A7TEW8_VANPO/8-101        AC A7TEW8.1
#=GS A0A4V3SJA8_9PEZI/31-105   AC A0A4V3SJA8.1
#=GS A0A1G4JIH5_9SACH/7-101    AC A0A1G4JIH5.1
#=GS A0A1E3NZU8_WICAA/4-95     AC A0A1E3NZU8.1
#=GS A0A5J5EIA9_9PEZI/16-91    AC A0A5J5EIA9.1
#=GS A0A367YGB9_9ASCO/8-113    AC A0A367YGB9.1
#=GS A0A2U9R9K9_PICKU/15-118   AC A0A2U9R9K9.1
#=GS H2AQT0_KAZAF/8-101        AC H2AQT0.1
#=GS I2GZ51_TETBL/9-102        AC I2GZ51.1
#=GS A0A899FV68_9ASCO/11-87    AC A0A899FV68.1
#=GS A0A2P7YQX7_9ASCO/4-102    AC A0A2P7YQX7.1
#=GS G3ASQ1_SPAPN/2-107        AC G3ASQ1.1
#=GS G8YUJ2_PICSO/8-113        AC G8YUJ2.1
#=GS M3JZL0_CANMX/6-70         AC M3JZL0.1
#=GS A0A3N4LKZ1_9PEZI/1-63     AC A0A3N4LKZ1.1
#=GS PFKA1_YEAST/8-101         AC P16861.1
#=GS G8ZYK1_TORDC/9-102        AC G8ZYK1.1
#=GS A0A875RQG0_EENNA/7-109    AC A0A875RQG0.1
#=GS A0A1Y2F859_PROLT/6-99     AC A0A1Y2F859.1
#=GS A0A421JAU2_9ASCO/5-106    AC A0A421JAU2.1
#=GS A0A1E4TKB2_9ASCO/7-78     AC A0A1E4TKB2.1
#=GS A0A1A0H5H7_9ASCO/4-103    AC A0A1A0H5H7.1
#=GS A0A2V1ASC6_9ASCO/4-103    AC A0A2V1ASC6.1
#=GS PFKA1_KLULA/6-99          AC Q03215.1
#=GS A0A1E4S9Y0_CYBJN/4-93     AC A0A1E4S9Y0.1
#=GS G8B6I7_CANPC/8-112        AC G8B6I7.1
#=GS A0A3N4KYQ6_9PEZI/12-87    AC A0A3N4KYQ6.1
#=GS A0A1E3NKK2_9ASCO/18-121   AC A0A1E3NKK2.1
#=GS A0A1E4SGV7_9ASCO/8-113    AC A0A1E4SGV7.1
A0A061ANW7_CYBFA/4-94                ......SGVSFTSFATGSTECYEAAVTWYRALGFKLVRTYN.RSVGG..SSVA.......aSG.ASFDSLRETWLESFELSET..-.KNGK..RVPLQESHS---....----R...ESEGCVLKIRL.................................
A0A1Q2YG84_9ASCO/18-121              ...shv---LYTSFAVISTSDYAALIQFYKKLGFRIVKTYS.KDHYV..SSNKt......iAG.ISTDSRKECWLESFPCSRT..D.TRGN..PVPFQETIEYSHpelsSSQAC...LNRGVVLKVRL.................................
C4Y0S9_CLAL4/4-108                   ......EGVSFISLVTADPTKFKEACEFYRRLGFRLAKNYS.KLSSS..GAAVahh.pklsSG.LCTDSIREVWLESFPLQNT..D.ENGC..VVPWQELRFYNG....DHTAP...LAPSTCLKIL-l................................
A0A4P6XDG7_9ASCO/4-103               ......EGVSAISLATSDENAFKNTSSFYRSLGFKLIKTYN.AVVSAglNNYL........QG.FASDSIKELWLEAFPLQTR..D.NAGN..VVPWQDLQFYNG....DATSA...LCSSTLLKLRL.................................
A0A8H8A6H9_9ASCO/200-266             ......NGLSSISFVTYLLEAYNKTIEFYCKIGFKKVFDYNsKDHDS..SVSS........MN.YLFKSKQEIWLSAL-----..-.----..------------....-----...-----------gkneei...........................
A0A1G4MJ32_LACFM/7-100               .....y-GVAFRSVATADESAYKDMIHFYHKLGFSSVKTYD.KFRSN..NKDFh......tSG.TAQDSIKETWLESFKLSEV..D.ADGF..RIPQQQATN---....---HE...QSEGALLKIRL.................................
A0A7H9B316_ZYGMR/8-101               .....y-GVAFASVVTAKESLFRDAIHFYHSLGFSTVKDFD.KFKHG..QNLIl......sSG.TSQESIKEVWLEAFKLSEI..D.ASGF..RVPQQEADN---....---KQ...QSQGALVKIRL.................................
B6JW37_SCHJY/7-80                    .....h-GISCFSLVAPNDETYDATLDFYTKLGFTKVANFG.VSDRS..DDN-........--.VCTDSVREDWLYSAGA---..-.----..------------....-----...-----------geasnitlklrlvps..................
G8JQL6_ERECY/7-100                   .....y-GVGFTSLTTAEEDKYKATIKFYQELGFSIVKIYD.KFKNH..DNGVi......aSG.TTHGSRKETWLESFKLSEM..D.ARGF..RVPQQEASN---....---PE...QSDGILLKIRL.................................
A3LNQ5_PICST/8-113                   ......QGLSFVSIVTNDQTKFEKLAKFYTRFGFKLSKNFS.KVSNN..GAASasnnprlhLG.VSNDSLREVWLESFPLQNL..D.GNGN..VTPWQELAVYDG....DNCEK...LCDSTLIKIRL.................................
A0A1E3PPM6_9ASCO/9-103               ......SGVSFISLATAEKSLFDAAVQFYVEFGFSVAQTNS.HVQPD..SVSH.......dAA.SASNTFEEVMLHTFAADST..-.SDGI..------------....-----...-----------tlkirltdngvsadeathqgdalal........
A0A5E8BYN4_9ASCO/12-97               ......NGISSLSIATSDETIYHRTVAFYQQFGFTKIHSYS.RGDPD.lTIERf.....lsAA.HAIDSIAESWLNLLPEPE-..-.----..------------....-----...-----------yghkdasedsgitlkirl...............
A0A1E4SYJ4_9ASCO/11-113              .....t-SFGFTSFTTIKTETYTSLIQFYKLFGFSVLKTYT.KDANT.iGIDL........NG.ISNDSRKECWIVSYPISRM..N.AFGE..IIPFQETLEYNM...pDLCSKlkdFNNCVILKLRL.................................
A0A2H0ZIL9_CANAR/4-103               .....d-SVSFISLVTTDAGLFKKTAQFYHALGFRLVKNYN.KVSTS..AASSi......vNG.ISADSSKEIWLEALPLQNL..D.EHGN..VVPWQEMPFYEG....DHTAP...LCKGTVVKIRL.................................
G0W9W5_NAUDC/8-101                   .....y-GVAFRSVVTTDDTLFQETIQFYHKLGFSTIKDFN.KFKNS..DNHLl......sVG.TSQDSIKEVWLEAFKLSEI..D.GQGF..RVPQQEAAN---....---KN...QSQGALLKVR-q................................
A0A376B6M1_9ASCO/26-119              .....y-GLAFRSVATHDPHLYHETIKFYHKLGFSTIKVYD.KFKNG..QNLLl......sNG.TSKDSLKETWLESFKLSEL..D.KDGF..RIPQQEAKL---....---GH...KSDGALLKIRL.................................
A0A8J5USS8_9ASCO/11-116              .....d-GISFISLVTNDKQKFEDSDKFYNNLGFRLTKSFS.RVTNS..SSAAvasnpklqLG.VAKESSREIWLESFPLQDV..D.ENGN..VRPWQELEVYDG....DSTER...LTESTVIKIRL.................................
A0A1S7HX15_9SACH/18-111              .....y-GVAFRSVVTDSEKLFHDTVHFYHTLGFSTVKDFD.KFKHG..ENILl......cSG.CCQDSLREMWLEAFKLSEI..D.ENGF..RIPQQEAGN---....---KH...QSQGALLKVRL.................................
A0A7H9HM78_9SACH/9-102               .....y-GVAFASVVTSDEDKFKESIQFYHSLGFSTVKDFN.KFKHG..ENLIl......sSG.TSQESLKEAWLEAFKLSEI..D.ESGF..RVPQQEAKN---....---KQ...QSGGALVKIRL.................................
A5E352_LODEL/8-112                   ....sr--LSYISLITNDQEAFLQLFKFYTNLGFRLTKNFS.RVSPN..GASAann.pqlqLG.VSKDSLREVWLESYPLQEL..D.DNGN..LRPWQEMSIYYG....DNCQK...LSESTIIKLRL.................................
J7SAR7_KAZNA/8-101                   .....c-GVAFRSLVTTDEKLFQQTIQFYHSLGFSTIKDYN.KFKHG..ENSLl......tAG.TSEDSLMEVWLESFKLSEL..D.ESGF..RVPQQEASN---....---KE...QSQGSLLKIRL.................................
A0A4C2DZF5_9SACH/9-102               .....y-GVAFRSVVTNSVELFKETIRFYHKLGFSTIKDFD.KFKHG..ENMLl......sSG.CSQDSIREMWLEAFKLSEV..D.ENGF..RVPQQEAGN---....---KR...QSEGALLKVR-f................................
PFKA1_KOMPG/7-112                    .....s-ALSFTSFVTNDDKLFEETFNFYTKLGFHATRSYV.KDNRS..DFEL........TG.ISTDSIKEIWLESFPLSEVveT.SAGRelRKPLQESVGYQSeallGYSPY...QSDGVVIKLRL.................................
Q758H0_ASHGO/7-100                   .....y-GVAFRSLATTDERLYKATVQFYKRLSFATVKLYD.KFKNH..GDEMl......lSG.TSQSSRHETWLMSFKLSEV..D.SSGC..RVPQQEAER---....---KL...QSDGAMIKVRL.................................
A5DIC5_PICGU/5-106                   ......NGISSISFVTTDPAELEAACKFYTSLGLRLTRSYP.KNTSG..FSSCpe....yhLG.VSSDSIQEIWFESFPLQDT..D.KNGC..LIPWQELPIYTG....DKSAK...LSQSFVIKIRL.................................
A0A8H7L8B7_9ASCO/4-103               ......EGVSAISLATSDENAFKNTSSFYRSLGFKLIKTYN.AVVSAglNNYL........QG.FASDSIKELWLEAFPLQTR..D.NAGN..VVPWQDLQFYNG....DATSA...LCSSTLLKLRL.................................
K0KJI7_WICCF/4-93                    .....t-GVAFTSFATKDIRPFEEAVKYYKALGFKLIRNYT.RDLNA..TSSV........RG.VSHDSSREVWLESFKLSQF..-.ENGS..RVPLQESNS---....----L...QSEGVVLKLRL.................................
A0A8H6BRQ2_CANAX/9-114               ....nr--ISYISLVTSDNDKFNQTFQFYSQLGFRLTKSFS.KVSSY..GSGLganhpefqLG.VSHDSLKEVWLESYPLQNV..D.SNGN..LRPWQEMEVYDG....DNCER...LNESTVIKVRL.................................
A0A1G4J735_9SACH/9-102               .....y-GVAFRSIATADEAVYREAIKFYHRLGFSTVKTYD.KFRGT..KQNIp......sSG.TAQGSVKETWLESFKLSEV..D.ANGF..RIPQQEASN---....---HD...QSDGASLKIRL.................................
A0A1X7R9N1_9SACH/8-101               .....y-GVAFTSLVTTDETLFKQTIRFYHSLGFATIKDFD.KFTTG..EDSLl......sIG.TSHDSIRETWLESFKLSEI..D.ELGF..RVPQQEAKN---....---SK...QSEGALLKIRL.................................
A0A1S7HE37_9SACH/18-111              .....y-GVAFRSVVTDSEKLFHDTVHFYHTLGFSTVKDFD.KFKHG..ENILl......cSG.CCQDSLREMWLEAFKLSEI..D.GNGF..RIPQQEAGN---....---KH...QSQGALLKVRL.................................
A0A1E3PPA8_9ASCO/5-80                .....p-GTSFFSLVTSTDIVFRSAVDFYTTLGFTALRTFN.SEDIF..STGVy......dSA.NALDTIKETWLHLFD----..-.----..------------....-----...-----------gpdsspvtikvrl....................
C5MJ51_CANTT/8-113                   ....nr--ISYVSLVTSVVEQFNDAFKFYSALGFRLTKNFS.RVSTN..GSASgshdpkllLG.VSHDSLKEVWLESYPLQEV..D.ENGN..IRPWQEMEVYDG....DNSEK...LTESTVIKIRL.................................
A0A1L0D5I0_9ASCO/4-109               ......QGVSFISLVTPDSQKFRNTIDFYLKLGFKLVKNYS.KISSN..GAASaankphlqLG.IANDSLKEVWLESFPLQNV..D.SAGN..IIPWQELDFYDG....DKTAQ...LGQSTVIKIRL.................................
A0A0C7N118_9SACH/7-100               .....y-GVAFRSVATTDETAYRQAIKFYHKLGFSTVKTYD.KFRGN..KQSTp......tSG.TAQGSVKETWLESFKLSEV..D.SNGF..RIPQQEASN---....---HN...QSDGALLKIRL.................................
G8BNW7_TETPH/8-101                   .....y-GVAFRSIATADETLFHSTIKFYHSLGFSTIKEFD.KFKHG..QNALl......sSG.TSEGSIKENWLEAFKLSEV..D.QAGF..RIPQQEASN---....---KK...QSQGALLKIRL.................................
PFKA_YARLI/3-65                      ......EGISFASFVTHEKPKFVRALDFYKALGFLPTKEYK.HGTDH.hATDE........EG.--AGSIQEVWLTS------..-.----..------------....-----...-----------sragv............................
A0A448YF46_BRENA/5-107               .....s-NVSFTSVTVVKTQDFEDLVKFYRSFGFNVVRIFN.KDANS.tGTEL........NG.ISSDSRSECWLVAYPVTRL..D.DTGN..VVPIQETVEYSHpelaSSISK...FNKGVVLKIRL.................................
A0A1E4RL19_9ASCO/6-111               ......EGVSFSSLVTNDAKKFEQTCQFYNQLGFRLTRNYS.KVSSN..GSTSsfndpklhLG.VSNDSLKELWLETFPLQTL..D.SNGK..IKPWQELPFYCG....DSTKC...LNNSTIIKLRL.................................
W1QIH3_OGAPD/5-89                    .....s-SFNFSSFVTTKTQDYVALIQFYKSFGLSVVKTFS.KDANT.aGTEL........IG.VSTDSRKECWFSCFPAADL..A.GHG-..-------PG---....---GA...FSKGTIIKLRL.................................
A0A421JQ79_9ASCO/2-107               ......EGVSFISLVTNSQDKFDQSAKFYGKLGFRLTKNFS.RISNS..GAEAaatsakahLG.ISKDSQREVWLESFPLQNL..D.QNGN..VRPWQELEVYDG....DSSEQ...LSEATMIKLRL.................................
A0A1E3QIB2_9ASCO/5-99                ......SGVAFTSLVTTSHEAYLAAIAFYTGLGFTIVRNYT.KTVNL..QEGSy.....nlAG.ISAGSLRECWLESFPLTPL..G.ATGA..KKPAQECTS---....---VQ...TTDETVLKLRL.................................
G0VGB3_NAUCC/8-101                   .....y-GVAFRSLATTDEQLFQNTVQFYHNLGFSTIKDFN.KFHNG..DNSIl......sTG.TSKDSIKETWLEAFKLSEI..D.AQGF..RVPQQEALN---....---KN...QSQGALLKVRL.................................
A0A167DNJ0_9ASCO/6-92                ......EGVSFLSLVTSDEKLFKDTLAFYKKLGFTIFQEYR.HNAPV.aTAGIq.....siTS.HAQASISEEWLTSIPINPN..N.----..------------....-----...-----------nedqvdkslgvtlkirl................
G8YT39_PICSO/8-113                   .....l-SIGFISLVTTDHDVFMRASQFYSELGFKLIKNYS.KISYH..GTSSggdnrstfLG.IASDSLREIWLESVPLQEL..D.KSGC..PIPWQECPEYNG....DGSQK...LNDPTVVKIRL.................................
G3B045_CANTC/4-100                   ......EGLSSISLVTDSPDKFTAAAKFYVRAGFTALKSYN.KHL-N..KPDL........LG.VSSDSIRELWLQSFPVEEV..D.SHGQ..VIPFQESAVYQG....DNCES...LSDPVLIKLRL.................................
A0A642UU77_DIURU/3-109               .....v-SLSYASIVVTNEKKLEELYHFYTRLGFRLTKSYS.KAGLS..THPApeegkstlIG.IASDSIRELWLESFPLQDT..DaATGK..IKPWQEMSVYQG....DVSEA...LGVASVLKLRL.................................
A0A0E9NS83_SAICN/12-85               ......QGVSFFSIVATTEDAFYDTVAFYGALGFRETSVFE.RGP-D..SQKT........AE.HSSDSAKETWLHAFA----..-.----..------------....-----...-----------dagngedvtlkirl...................
Q6BH76_DEBHA/9-110                   ......EGISFISLITNKNEEFEESANFYNKLGFRLTKNFS.KITNN..SESKpk....lqIG.ISNDSLKELWLESFPLQNT..D.ENGF..IRPWQELSVYDG....DGCEK...LNSATTLKIRL.................................
I2K2U6_DEKBR/9-111                   ....sk--VAFTSLTTAKRQQYDELIKFYRKFGFKVIRIFN.KDANA.tGADL........NG.ISFDSRSECWLATFPVSRV..D.KSGN..VIPYQETPEYKHremdPVLDK...YNEGVMLKVRL.................................
PFKA_SCHPO/7-77                      .....h-GISCYSVVANTEDTYNQTLDFYQKLGFKKVASFG.TSD--..-SDN........AR.VCNESLREDWMH-------..-.----..------------....-----...-----------vagnnsaesvtikfrl.................
A0A7D9GWT9_DEKBR/9-111               ....sk--VAFTSLTTAKRQQYDELIKFYRKFGFKVIRIFN.KDANA.tGADL........NG.ISFDSRSECWLATFPVSRV..D.KSGN..VIPYQETPEYKHremdPVLDK...YNEGVMLKVRL.................................
J8Q4Q3_SACAR/8-101                   .....y-GVAFRSIITNDEALFKKTIHFYHTLGFATVKDFN.KFKHG..ENSLl......sSG.TSQDSLREVWLESFKLSEV..D.ASGF..RIPQQEASN---....---KA...QSQGALLKIRL.................................
A0A512U890_9ASCO/4-103               ......EAVSAIALATTDEEAFKNTSSFYRSLGFKLVKNYS.AMASA..GSNNy......fQG.FATDSIKEYWLEAFPLQNT..D.NAGN..LLPLQELQYYTG....DSTSA...TCPTTLIKLRL.................................
A0A1D2VPR3_9ASCO/7-103               ....td--LSYVSLTTSSLDRYEKTIQFYRSIGYQIARNFT.KDPAN..SSLTndsihsnkIG.ISNDSFKESWLECFSSS-T..N.SSGS..A-----------....-----...-----------ikirlsatsanlkvstnqi..............
A0A4T0WZD1_9ASCO/22-126              ....nn--ILYTSFTVVSNDDYEELIKFYTNLGFRIIRTFE.KEDTRylPASA........IGdISLDSRRECWLEFFPVCRK..D.KHGN..VIPIQETIEYKHpelkSKLSE...VNTGVSLKIRL.................................
M7PLJ6_PNEMU/11-102                  .....d-GLSSISFITYSLESYYKAIEFYCKIGFKEIFHYD.RKEEH.iSRSL........ID.FSFKSDREIWLY-------..-.----..------------....-----...-----------ilggkekeltikihfyhndiskkstkltdscqk
A0A1E4TTN8_PACTA/9-108               .....s-GYAYFSFTTNDSEKFEKAVSFYKALKFQPAREFS.KGIKD..ESNL........RG.VSRDSLKEVWLESFPLGPL..H.QDALdsRLPVSEVIEDVS....SLKNY...ETQGVVLKIRL.................................
C5DCN7_LACTC/7-99                    .....y-GVAFRSVATADESAYRSAIKFYHKLGFSTVKTYD.KFRGN..KEAA.......tSG.TAQGSVKETWLESFKLSEV..D.SNGF..RIPQQEATN---....---HE...QSDGALLKIRL.................................
W7HWB6_9PEZI/14-90                   .....a-GVSFISLVAPDEDLFYETITYYTDLGFAETLVYD.RANPS.vGEHK........DD.LCFLSDKETWLHS------..-.----..------------....-----...-----------daeyegqgtaitikvrl................
Q6FTX6_CANGA/8-101                   .....y-GVAFRAIATADEELFKQTVRFYHSLGFSTIKDFN.KFKHG..ENVVl......aSG.TSDDSLREVWLESFKLSET..D.SLGF..RVPQQEASN---....---KA...QSQGAFVKVRL.................................
Q5AK53_CANAL/9-114                   ....nr--ISYISLVTSDNDKFNQTFQFYSQLGFRLTKSFS.KVSSY..GSGLganhpefqLG.VSHDSLKEVWLESYPLQNV..D.SNGN..LRPWQEMEVYDG....DNCER...LNESTVIKVRL.................................
A0A4P9ZF45_9ASCO/4-106               ......EGVSLISLNTADQVKFNATASFYTALGFSLVKSYS.KYSLV..ANELkt...eqlWG.ITHDSLREAWLQTVPTQKT..D.KDGN..IVPWQEMPFYNG....DETKL...LFAGMLLKLRL.................................
A7TEW8_VANPO/8-101                   .....y-GVAFRSLATADNDLFHQTVKFYHSLGFSTIKDFD.KFRHG..QNSLl......aSG.TSDGSMKEVWLEAFKLSEV..D.ESGF..RIPQQEASN---....---RH...QSQGALLKLRL.................................
A0A4V3SJA8_9PEZI/31-105              ......SGVSFISLVAPNETVFYETVTFYTDLGFQETAVYD.RTRSG..QERE........AT.HCVLSEKETWLYSA-----..-.----..------------....-----...-----------geredegtditlkvr..................
A0A1G4JIH5_9SACH/7-101               .....y-GVAFRSVATADEAAFRNTIKFYHKLGFSTVRTYD.KFRGA..GENIl.....qvSG.TAQESIKETWLESFKLSEV..D.ADGF..RIPQQEASN---....---HE...QSDGALLKIRL.................................
A0A1E3NZU8_WICAA/4-95                ......SGVAFTSFATKDLKTFEEAIGFYKSLGFKLIRNYT.RDLNA..SSSL........KG.VSHDSLRETWLESFKISQV..DpKNGA..RIPLQESNS---....----I...QSEGVVLKLRL.................................
A0A5J5EIA9_9PEZI/16-91               ......SGISFFSLVAPNEELFYNTVAFYLDFGFKEVAVYD.RNSPK..QKGD........TD.HCATSEKETWL--------..-.----..------------....-----...-----------lvngegdaqgnditikirl..............
A0A367YGB9_9ASCO/8-113               ....nr--ISYVSLVTNDPEKFDASFKFYNAMGFRLTKNFS.RVSTN..GAASgshdpkllLG.VSHDSLREVWLESYPLQEV..D.SNGN..LRPWQEMEVYDG....DNSQK...LTESTVVKLRL.................................
A0A2U9R9K9_PICKU/15-118              ....sn--VLYTSFTVNKTSDYTSLIKFYNSLGFKIIKTYS.KEESL..TSSId......iQG.VSTDSRKECWLESFPITRT..D.SNGK..IIPFQETIEYKYpqltPQLAK...LNKGVVLKIRL.................................
H2AQT0_KAZAF/8-101                   .....y-GVAFRSLATTDASVFKKTIQFYHLLGFSTIKEFD.KFKHG..QNPLl......tSG.TSEDSLKEVWLEAFKLSEI..D.DLGF..RVPQQEASN---....---KE...QSQGALLKVRL.................................
I2GZ51_TETBL/9-102                   .....y-GVAFRSIATVDQTLFQKTIKFYHSLGFQTIKHYD.TFKNG..QNSLl......sNG.TSVDSLNEVWLEAFKLSEI..D.NTGF..RVPQQEATN---....---KN...QSQGALIKIR-y................................
A0A899FV68_9ASCO/11-87               .....d-GLSSISFITHSLESYYKAIEFYSKIGFKKIFHYDcKERNT..DRSL........VD.SSLKGDREIWLHIL-----..-.----..------------....-----...-----------gakkkeliikihfydd.................
A0A2P7YQX7_9ASCO/4-102               ....sl--VSFVSLVTADSREFQRTAAWYHALGFRLVKNYN.KVSTA..SSQV.......vLG.ISGDSSKEIWLEALPLQNL..D.ASGN..VVPWQELSIYEG....DDTSK...LCNGTVVKIRL.................................
G3ASQ1_SPAPN/2-107                   ......EGLSFISLVTNSQDKFDNIARFYGKLGFRLTKNFS.RVTSN..GAEAaatnpkshLG.ISKDSTREIWLESFPLQNL..D.KNGN..IRPWQELEVYDG....DSSEK...LSTETTLKLRL.................................
G8YUJ2_PICSO/8-113                   .....l-SIGFISLVTTDHDVFMRASQFYSKLGFRLIKNYS.KISYH..GSLSggdnrstlLG.IASDSLREIWLESVPLQEL..D.KSGC..PIPWQECPEYSG....DGCQR...LNDPTVVKIRL.................................
M3JZL0_CANMX/6-70                    aasgtn-----------------------------------.----H..-PEL.......qLG.VSNDSVREVWLESYPLQNL..D.SNGN..LRPWQELEIYDG....DNCTK...ISESTVIKVRL.................................
A0A3N4LKZ1_9PEZI/1-63                ......SGVSFISVIAPTETLFQSTLDFYKTLGFYQAVVYD.RADSH..SKRQ........DD.HAFTSEKETWLQ-------..-.----..------------....-----...-----------npapt............................
PFKA1_YEAST/8-101                    .....y-GVAFRSIITNDEALFKKTIHFYHTLGFATVKDFN.KFKHG..ENSLl......sSG.TSQDSLREVWLESFKLSEV..D.ASGF..RIPQQEATN---....---KA...QSQGALLKIRL.................................
G8ZYK1_TORDC/9-102                   .....y-GVAFASVTTNDENKFRDCIQFYHSLGFATVKDFN.KFKHG..ENLIl......sSG.TSQDSLKEAWLEAFKLSEM..D.ESGF..RIPQQEAKN---....---KH...QSGGALIKIRL.................................
A0A875RQG0_EENNA/7-109               .....s-NISFTSFSASKTKDYEDLISFYRSFGFRVVRIFN.KDASS.tGIEL........NG.ISSDSRNECWLAAYPVTRL..D.TRGN..VIPFQETAEYTHpeleSDLAR...FNKGVMLKIRL.................................
A0A1Y2F859_PROLT/6-99                .....a-GLDSLTLRAFDQAGYFETIEFYASLGFIETKSFS.SADEN..SEPV........DG.FSTESEREAWLINFD-EET..D.ETV-..------------....-----...-----------vlkivvlknndekaskprssftlktr.......
A0A421JAU2_9ASCO/5-106               ......NGISSISFVASDPAELEATGKFYTSLGLRLTRSYS.KNTAG..FSSSpe....yhLG.VSSDSVREIWLESFPLQDT..D.KNGC..LIPWQELPIYTG....DKSAK...LSQSFVIKIRL.................................
A0A1E4TKB2_9ASCO/7-78                .....d-STSFLSFPTNSEETYHKAIDFYKKLGFEVTQEWD.VSHPA..LHRT........AE.QSAESVKESWML-------..-.----..------------....-----...-----------aisgessvtikirl...................
A0A1A0H5H7_9ASCO/4-103               ......EGVSAISLATTNEDVFASTSKLYRLLGFKLVRNYS.AMASHgpNNHL........RG.FASDSIKEHWLEAFPLQTR..D.SAGN..VVPWQDLRFYVG....DNTRP...LCPGTLVKLRL.................................
A0A2V1ASC6_9ASCO/4-103               .....d-SVSFISLVTTDPTLFKKTATFYHALGLRLVKNYN.KVSSS..VASTi......vHG.ISGDSSKEIWLEALPLQNL..D.SDGN..VVPWQEMPFYEG....DHTAQ...LCKGTVVKIRL.................................
PFKA1_KLULA/6-99                     .....y-GVAFRSLSTGDEKLYKEATRFYHSLGFQTVKLYD.NFKNH..DDSNl......iVG.TSKNSVKECWLESFKLSEL..D.SQGF..RVPQQEASN---....---QL...QTDGVMIKLRL.................................
A0A1E4S9Y0_CYBJN/4-93                .....t-GVAYTSLATGDSSKYTETVQYYRKLGFTLIRSFD.RNISQ..LSSS........KG.VAHDSLKETWLESFKLGQF..Q.GVN-..RVPLQESNS---....----I...QSEGVVVKIRL.................................
G8B6I7_CANPC/8-112                   ....qr--LSYVSFITTDYDKFLQSYKFYSNLGFRLTKNFS.RVTTD..GASGafk.pqmqLG.VSKDSLREVWLESYPLQEL..D.DNGN..LRPWQEMKVYTG....DDGER...LTDSTVIKIRL.................................
A0A3N4KYQ6_9PEZI/12-87               ......SGVSFVSLVAPTEDLFYSTVEFYTDLGFKETFVYD.RTHPT..TKRE........VD.HCLSSEKETWLYSQSE---..-.----..------------....-----...-----------ssnesndislkirf...................
A0A1E3NKK2_9ASCO/18-121              ...shv---LYTSFAVISTSDYAALIQFYKKLGFRIVKTYS.KDHYV..SSSKt......iSG.ISTDSRKECWLESFPCSRT..D.TKGN..LIPFQETIEYSHpelsSSQAC...MNRGVVLKVRL.................................
A0A1E4SGV7_9ASCO/8-113               ......QGISFTSLVTNDPAKYAQLGQFYHQLGFRLTKNYS.KVSNN..GAASasnnprlhLG.ISNDSLNELWVESFPLQNV..D.ANGH..ILPWQELPVYNG....DNCAP...LSASTVLKLRL.................................
#=GC seq_cons                        .......GluFhSlsTscpptFcpslpFYppLGFphlKsas.Khpss..sssh........tG.hSpDSl+EsWLEoF.Lpph..D.psG...hlP.QEh............tt....spusllKlRL.................................
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