GenomeNet

Database: Pfam
Entry: Ploopntkinase3
LinkDB: Ploopntkinase3
Original site: Ploopntkinase3 
#=GF ID   Ploopntkinase3
#=GF AC   PF18751.2
#=GF DE   P-loop Nucleotide Kinase3
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Iyer LM
#=GF GA   27.00 27.00;
#=GF TC   27.00 51.40;
#=GF NC   26.90 25.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   23814188
#=GF RT   Computational identification of novel biochemical systems
#=GF RT   involved in oxidation,  glycosylation and other complex
#=GF RT   modifications of bases in DNA.
#=GF RA   Iyer LM, Zhang D, Burroughs AM, Aravind L;
#=GF RL   Nucleic Acids Res. 2013;41:7635-7655.
#=GF DR   INTERPRO; IPR040717;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A P-loop Nucleotide Kinase predicted to be involved in modified
#=GF CC   base biosynthesis [1].
#=GF SQ   25
#=GS Q716S4_9CAUD/6-188      AC Q716S4.1
#=GS A0A2S9Z300_9CORY/1-179  AC A0A2S9Z300.1
#=GS A0A2Z4Q6Y6_9CAUD/1-194  AC A0A2Z4Q6Y6.1
#=GS S5Z5G9_9CAUD/1-177      AC S5Z5G9.1
#=GS A0A0F6WDP6_9CAUD/1-192  AC A0A0F6WDP6.1
#=GS A0A386KB41_9CAUD/1-180  AC A0A386KB41.1
#=GS G8I9C4_9CAUD/8-198      AC G8I9C4.1
#=GS S5Y177_9CAUD/1-177      AC S5Y177.1
#=GS A0A0F6YRW9_9CAUD/1-186  AC A0A0F6YRW9.1
#=GS A0A385UL22_9CAUD/1-186  AC A0A385UL22.1
#=GS A0A1C9M230_9CAUD/6-188  AC A0A1C9M230.1
#=GS Q0RM57_FRAAA/1-121      AC Q0RM57.1
#=GS A0A2P1CFV6_9CAUD/1-198  AC A0A2P1CFV6.1
#=GS S5Y5G5_9CAUD/1-187      AC S5Y5G5.1
#=GS A0A1L6BYU5_9CAUD/1-186  AC A0A1L6BYU5.1
#=GS B3VM26_9CAUD/1-193      AC B3VM26.1
#=GS A0A345KWG6_9CAUD/1-194  AC A0A345KWG6.1
#=GS W8EJD7_9CAUD/1-186      AC W8EJD7.1
#=GS X2KMP3_9CAUD/6-188      AC X2KMP3.1
#=GS T2A8V0_9CAUD/1-193      AC T2A8V0.1
#=GS V5UNI0_9CAUD/11-203     AC V5UNI0.1
#=GS X4Y6T1_9CAUD/3-185      AC X4Y6T1.1
#=GS A0A2P1JWE1_9CAUD/6-188  AC A0A2P1JWE1.1
#=GS A0A2P1CFE4_9CAUD/1-198  AC A0A2P1CFE4.1
#=GS A0A455LN94_9CAUD/1-182  AC A0A455LN94.1
Q716S4_9CAUD/6-188                 ....TNHRLIYLIGAPGAGKSTMMAHLTDCFDREH..V.P...GTD....TAPAYDLLKYTDGEVA...GVELGKRRPQFSGTDALPASIIEKAIPWL.......NT.......KPFR..LVFAEGARLANKRFLDAAVAAGYEVHLGWLNHPDVDAWRAARSAEVGKV.QSEAWVKGRVTAVTKLVENYIN.........RPARG-..VKVYVGGPEQLTSDMEHLL-g.......................
A0A2S9Z300_9CORY/1-179             ...m---QLIYLIGPPGAGKSTTMRRITAHLDRTP..M.P...KDQ....YPARDALFD--NGTLW...GIELGARRPTFSGTDALPMNANTAACNYL.......TH.......APEQppTILAEGARLANAKFLTTATKAGYDTHLVYIDNPHARQWALDRAAAHHTTpQSESWAKGRATAARNLAARP--.........--PAGV..TVHTVTHPDAAADTIAAI--lr......................
A0A2Z4Q6Y6_9CAUD/1-194             mtda-----LYLLGAPGVGKSTVMRGVIDHLGLDV..N.P...DNYrihkRLTGHGLFEWTTGETM...GVYLGKHREEFPGTDGLSMAVAPDAREWA.......ATlrr.dreEGVR..YVFGEGARLGNVGFLTALAEHT-WLTVVHLTADE--DALTARRDERGSA.QRPSWMRGATTAAANTFTAV--.........QALTGK..VN------------------ravemnttdeapdilaeriaglig
S5Z5G9_9CAUD/1-177                 ....MTYRMIYLVGQPGSGKSTLMAELTRPYDLLV..R.E...--E....TVPHLGLIDRTTGEVI...GAEIGKRRDSFSGTDALASAIIDKAVPWV.......ST.......RPYE..MLLAEGARLANARFLDAAIAAGYDLTVALLDHDQAEEWRLARSRKLKRV.QNESWVKGRLSASRNLADAM--.........---KGK..ARVLRGHPDQLRQGLQEIIA........................
A0A0F6WDP6_9CAUD/1-192             ....MKPRMIYLVGQPGAGKSTLMAALTKGLVRSP..W.H...-EH....TVPHDQLVDRVTGETV...AAELGVQRGAFSGTDALASSIIDKAVPWI.......QS.......RPYD..LVLAEGARLANRRFIDAALDAGYAVTIGLLDHDQADTWRKRRSKALGRE.QSPSWVKGRLTASRNLAAHYPGalvvagsviPAEPGK..AIVLAGHPDELEPILAAVMA........................
A0A386KB41_9CAUD/1-180             ....MTHCLIYLVGPPGSGKSTLMARLTGPLERIP..FyD...PRA....VVAHDQLF--ADDELV...GAEIGIRRELFSGTDALPASIIEKAVPWV.......QT.......MPYR..LLLAEGQRLANRRFLTAAADAGYEVVLALLDHEDTEDWRRKRARAIGRT.QNAAWVKGRISASRNLAEQMRD.........---RQN..VTVLTGHPDELYPVLEQLV-g.......................
G8I9C4_9CAUD/8-198                 ....MTPRMIYLVGQPGSGKSTLMAALTKGLVRSP..W.E...--H....TVPHDQLVDRVTGAVV...GAEIGKQRGAFSGTDALASSIIDKAVPWV.......QQ.......QPYD..LLLAEGARLANKRFIQATADAGYAVMLGLLDHDAAEGWRKKRSKAIGRD.QNPSWVKGRLTASRRLADAYPSalvvagsviAPEPGK..VVVLKGHPDELEPVLAAFM-s.......................
S5Y177_9CAUD/1-177                 ....MTYRMIYLVGQPGSGKSTLMAELTRPYDLLV..R.E...--E....TVPHLGLIDRTTGEVI...GAEIGKRRDSFSGTDALASAIIDKAVPWV.......ST.......RPYE..MLLAEGARLANARFLDAAIAAGYDLTVALLDHDQAEEWRLARSRKLKRV.QNESWVKGRLSASRNLADAM--.........---KGK..ARVLRGHPDQLRQGLQEIIA........................
A0A0F6YRW9_9CAUD/1-186             ....MSPRLIFIVGGPGSGKSQLMADLTAPYQRIP..V.N...QKHp..eWVLHDMLRDPATGAVI...GAELGQRRGLFAGTDTLASAIIDKAVPWI.......EV.......HPYD..LILAEGARLATPRFLQSALDAGYDVTVALLDHDQAEPWREERARKLKRV.QNEAYVEARRSSARSFADTAIK.........LKGRYP..VRVWIGHPDDMRQGLQEIIA........................
A0A385UL22_9CAUD/1-186             ....MNPRLIFIVGGPGSGKSTLMADITDPYQRIP..V.N...QKHp..eWVLHDMLRDPATGAVI...GAELGVRRGLFSGTDTLASAIIDKAIPWI.......EA.......HPYD..LILAEGARLATPRFLQAAVNAGYDVTIALLDHDQAEAWREDRARKLKRV.QNEAWVDARRSSARSFADAAVK.........LKGRYP..VRVWTGHPDDLRQGLQEIIA........................
A0A1C9M230_9CAUD/6-188             ....TNHRLIYLIGAPGAGKSTMMAHLTDCFDREH..V.P...GTD....TAPAYDLLKYTDGEVA...GVELGKRRPAFSGTDALPASIIEKAIPWL.......NT.......KPFR..LVFAEGARLANKRFLDAAVAAGYEVHLGWLNHPDVDAWRAARSAEVGKV.QSESWVKGRVTAVTKLVENYIN.........RPERG-..VKVYVGGPEQLTSDMEHLL-g.......................
Q0RM57_FRAAA/1-121                 ...m-------------------------------..-.-...---....----------------...--ELGRRRRAFSGTDALPMDAVVAAERYV.......RSgq...aaRETA..LLLGEGARLGCARFLAAAVAGGWTVELVYLHGTEVAAQRRAGRA---AG.QDERWVRGAATRARRLAEG---.........------..--------------------ppagvlvhrvdvaaevtl......
A0A2P1CFV6_9CAUD/1-198             ...m--KRLVYVIGYPGAGKSTLFSGVTDRHGPHE..E.AvlrSEQ...aQVRGVERTRHLRGVLLgndGVTLGRVGTAFPGVDGMQRDTQAMARDWLadgapmpTK.......RQNR..WILLEGALLAHPKFMTVAAEH-TRLTLLVVSAADSEERARARADEIGSEyQKENWRKGKITQVDNLVNWSID.........QGIETLelHNDIPGQTDDLVDILE----gll.....................
S5Y5G5_9CAUD/1-187                 ....MTARLIYLVGQPGSGKSTLMSALTAGFDRHK..I.A...PAPd..yPVAHDVLADKTTGEVV...GAELGVRRELFSGTDALPSSIIDKAAPWV.......RS.......QPYP..LLLAEGARLANRRFIDAALEGGYEVTLVLLDHNDAEDWRKVRSKAIGKT.QNPSWVKGRLSASRNLADALSG.........PAYEGK.aVEVLRGHPDPIRSILKGIDA........................
A0A1L6BYU5_9CAUD/1-186             ....MSPRLIFIVGGPGSGKSQLMADLTAPYQRIP..V.N...QKHp..eWVLHDMLRDPATGTVI...GAELGQRRGLFAGTDTLASAIIDKAVPWI.......EV.......HPYD..LILAEGARLATPRFLQSALDAGYDVTVALLDHDQAEPWREERARKLKRV.QNESYVEVRRSSARSFADTAIK.........LKGRYP..VRVWAGHPDDLRQGLQEIIA........................
B3VM26_9CAUD/1-193                 ....MTPRMIYLVGQPGSGKSTLMAALTKGLVRCS..I.D...TEA....PVPHDLLLDRVTGCAV...GAEIGKQRGAFSGTDALASSIIDKAVPWV.......QS.......HPYD..LLLAEGARLANKRFIQAAADAGYAVMLGLLDHDQADAWRKKRSKAIGRE.QNPSWVKGRLTASRRLAEAYPSafvvggaviAPEPGK..VITLAGHPDELEPVLAAFM-v.......................
A0A345KWG6_9CAUD/1-194             ....MTPRMIYLVGQPGAGKSTLMASLTKGLVRST..I.D...DSG...tLVPHDVLVDRVTGAVV...GAEIGKRRGAFSGTDALASSIIDKAVPWV.......HT.......QPYD..LLLAEGARLANKRFIDSAAEAGYAIILGLLDHDQADAWRKQRSKAIGRE.QNPSWVKGRLTSSRKLGAAYPSafvvggaviAPEPGK..VITLAGHPDELEPVLAAF--is......................
W8EJD7_9CAUD/1-186                 ....MTARLIYLVGQPGSGKSTLMSKLTAGFDRHK..I.A...PNEa..yPVAHDVLTERVTGEVV...GAELGVRRELFSGTDALPSSIIDKAAPWV.......RS.......QPYP..LLLAEGARLANRRFIDAALEGGYEVTLVLLDHNDAEDWRKVRSKAIGKT.QNPSWVKGRLSASRNLADALTG.........PAYQGK.aVSVVRGHPDPILSVLK----tgv.....................
X2KMP3_9CAUD/6-188                 ....TNHRLIYLIGAPGAGKSTMMAHLTDCFDREH..V.P...GTD....TAPAYDLLKYTDGEVA...GVELGKRRPQFSGTDALPASIIEKAIPWL.......NT.......KPFR..LVFAEGARLANKRFLDAAVAAGYEVHLGWLNHPDVDAWRAARSAEVGKV.QSESWVKGRVTAVTKLVENYIN.........RPERG-..VKVYVGGPEQLTSDMEHLL-g.......................
T2A8V0_9CAUD/1-193                 ....MTPRMIYLVGQPGSGKSTLMAGLTKGLVRCS..L.D...AET....PVPHDLLLDRVSGAAV...GAEIGKQRGAFSGTDALASSIIDKAVPWV.......QT.......QPYD..LLLAEGARLANKRFIQATADAGYAVMLGLLDHDAAEGWRKKRSKALGRE.QNPSWVKGRLTASRRLADAYPSalvvagaviAPEAGK..VVVLKGHPDELEPVLAAFMA........................
V5UNI0_9CAUD/11-203                ....MTPRMIYLVGQPGSGKSTLMAALTKGLVRCP..I.D...TEA....PVPHDLLLDRVTGCAV...GAEIGKQRGAFSGTDALASSIIDKAVPWV.......QS.......HPYD..LLLAEGARLANKRFIQAAADAGYAVMLGLLDHDQADAWRKKRSKAIGRE.QNPSWVKGRLTASRRLAEAYPSafvvagaviAPEPGK..VITLAGHPDELEPVLAAFM-v.......................
X4Y6T1_9CAUD/3-185                 ....TNHRLIYLIGAPGAGKSTMMAHLTDCFDREH..V.P...GTD....TAPAYDLLKYTDGEVA...GVELGKRRPQFSGTDALPASIIEKAIPWL.......NT.......KPFR..LVFAEGARLANKRFLDAAVAAGYEVHLGWLNHPDVDAWRAARSAEVGKV.QSEAWVKGRVTAVTKLVENYIN.........RPERG-..VKVYVGGPEQLTSDMEHLL-g.......................
A0A2P1JWE1_9CAUD/6-188             ....TNHRLIYLIGAPGAGKSTMMAHLTDCFDREH..V.P...GTD....TAPAYDLLKYTDGEVA...GVELGKRRPAFSGTDALPASIIEKAIPWL.......NT.......KPFR..LVFAEGARLANKRFLDAAVAAGYEVHLGWLNHPDVDAWRAARSAEVGKV.QSESWVKGRVTAVTKLVENYIN.........RPERG-..VKVYVGGPEQLTSDMEHLL-g.......................
A0A2P1CFE4_9CAUD/1-198             ...m--KRLVYIVGYPGSGKSTLFTGVTDRHAPHKdvI.L...RTEl..aTVRGVERERHLRGVLLgndGVTLGRVGTAFPGVDGMQRDTQAMARDWL.......AAgapmptkRQNR..WILLEGSLLAHDKFMSVAHEH-TRLTLLVVTAADSEARARARADSIGSEyQKDSWRKGKITQTDKIVNWAID.........HGVET-..LEVTNDIPGQ----------tedlvdiveell............
A0A455LN94_9CAUD/1-182             ....MTNRLIYLVGQPGSGKSTLMADLTAHFDRHH..I.G...AAPd..yPVAHDVLTSRPDGRVV...GAELGVRRQHFGGTDALPSSIIEKAVPWI.......ET.......TPYQ..LVLAEGARLANRRFIQAAINGSYQPVIVLLDHPQAEEWRKARSEELGRT.QDPSWVKGRLTSSRRLAEWAKD.........----QA..IEVIEGHPDEIAAQLGEII-s.......................
#=GC seq_cons                      ....Ms.RLIYLVGtPGuGKSTLMApLTcsasRp...l.s...spp....sVsHc.Lh-hssGpVl...GAELG+RRstFSGTDALsuSII-KAlPWl.......po.......+PYc..LlLAEGARLAN+RFlsAAlcAGYcVpLuLLDHspA-sWRcsRSctlG+s.QstSWVKGRlTAuRpLA-sh.s..........s.pG...VpVhsGHPDpLpssLttlh.........................
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