#=GF ID   RE_AccI
#=GF AC   PF09545.14
#=GF DE   AccI restriction endonuclease
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Bateman A
#=GF GA   22.00 22.00;
#=GF TC   23.70 23.40;
#=GF NC   19.00 18.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   6278447
#=GF RT   Purification and characterization of two new modification
#=GF RT   methylases: MClaI from Caryophanon latum L and MTaqI from
#=GF RT   Thermus aquaticus YTI. 
#=GF RA   McClelland M; 
#=GF RL   Nucleic Acids Res. 1981;9:6795-6804.
#=GF DR   INTERPRO; IPR019054;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family includes the AccI (recognises and cleaves GT^MKAC)
#=GF CC   restriction endonuclease.
#=GF SQ   21
#=GS A0A1J0ADQ5_9CYAN/1-65     AC A0A1J0ADQ5.1
#=GS A0A133UIN1_9EURY/8-134    AC A0A133UIN1.1
#=GS A0A1J0ADR1_9CYAN/5-251    AC A0A1J0ADR1.1
#=GS E0ST79_IGNAA/1-143        AC E0ST79.1
#=GS A0A1J0ABE2_9CYAN/2-131    AC A0A1J0ABE2.1
#=GS A0A5C2HP13_9GAMM/1-351    AC A0A5C2HP13.1
#=GS G2LH25_CHLTF/35-156       AC G2LH25.1
#=GS G2LH25_CHLTF/182-318      AC G2LH25.1
#=GS A0A554WZD2_9BURK/1-322    AC A0A554WZD2.1
#=GS A0A133UIN1_9EURY/128-262  AC A0A133UIN1.1
#=GS A0A1M6HEU2_9BACT/1-366    AC A0A1M6HEU2.1
#=GS J9QU37_RIEAN/1-366        AC J9QU37.1
#=GS A0A081BR11_9BACT/2-351    AC A0A081BR11.1
#=GS K7WVD9_9NOST/32-186       AC K7WVD9.1
#=GS A0A552A3B3_MICAE/1-351    AC A0A552A3B3.1
#=GS R5AUM7_9BACE/1-366        AC R5AUM7.1
#=GS A0A142HF98_9BACT/1-366    AC A0A142HF98.1
#=GS K9YRL1_DACSA/1-350        AC K9YRL1.1
#=GS K7WVD9_9NOST/181-311      AC K7WVD9.1
#=GS Q30UC2_SULDN/1-366        AC Q30UC2.1
#=GS A0A1J0ABD9_9CYAN/7-170    AC A0A1J0ABD9.1
A0A1J0ADQ5_9CYAN/1-65                ..............................m--YKDDILNLIKQLPFEIN--TEIQMTGSPPSTAYSEFLTNKEQGDWAEKIVFKAINEYSRDYFAVQY----.-------.----------------------------......--...--...---...---------------------------------------------------------.-.-.-------------------------------------------------------------------------------------------------------------------..---..-----.----.....--.-----...-----------------------------------------------------------.........................................................
A0A133UIN1_9EURY/8-134               ...........................prgl------------------------------------DFYRKWSQGSWAEEKLKEAINRT-KDYSAYQYGPSRgEPFHTIE.EFEKYNQEYSRKEDKFGKRPDLLVFNDSt...ieDFsieDK...ETL...NELEEISDSKAEEVISSSSGGIEVETSIWKIEKR-----------------------.-.-.-------------------------------------------------------------------------------------------------------------------..---..-----.----.....--.-----...-----------------------------------------------------------rrngk....................................................
A0A1J0ADR1_9CYAN/5-251               .....................viislfnien------------------------------------------------------------------------.-------.----------------------------......--...--...---...-----------SEHIRSAVAALEVRSSSYLAGKYAVFMNNRQRQAIDKCHEIRNAIIgT.D.LSDLLKRKNETIY-NLISNATDDTFRELDFRCPSWSSTQELINLRKLLKGIKENIEVLHKRDYLSITPKMEDIALVNRWIQQYNVKHFYLQVFFDRAYIISFKNILTFVSNDNND..GNN..FSIER.DDKN.....QG.KTTIK...INVQIGKEVLGKIDMPEHKSAMKELDRGRLLFYVTFEGGKGYLDNEIF-----------irdvidv..................................................
E0ST79_IGNAA/1-143                   ...........................mkkp----------------------------KIPKPRGVDFLINWSMGSWSEDRVLEAINDTGR-YVAVRYGVSR.AGSFSFE.EYARYYQRLQR-MYLHGKRPDLLVFDSN......TY...QElkqRWGsimDNLMDVPNSEADKVVEEALFGVEVEVSKWHVGKMLEYQGKKRRK-------------.-.-.-------------------------------------------------------------------------------------------------------------------..---..-----.----.....--.-----...-----------------------------------------------------------tsilg....................................................
A0A1J0ABE2_9CYAN/2-131               .............................pt------------------------------------------------------------------------.-------.----------------------------......--...--...---...---------------------------------------------------------.-.-.-----------------------------------------------------------------IIIKEEDREPLQAWQNSTGIPIHIWHVFFDMAYGISFNEAQRLIREGYTL..PTK..QTFQApGGAT.....TE.KSLYK...FYYHYGYSLSDAVEEPRLVAKSITDKNGHILPYVHFENGIMSIHEEALNIL--------reirnak..................................................
A0A5C2HP13_9GAMM/1-351               ..............................m--YKDDILNLIQQSPLEID--TEIQMTGRPPTMANSEFLTNKEQGDWAEKVVYRAINEFSSDYFAVQYGRSD.SIVAGDD.GFADFYMEYQSELNTIGKRPDLLIFKLT......DF...PD...-RD...VDIE------NDEHVRKAVVALEVRSSSFLIDKYTAFMDERQQEAIKNCTDIRKNLL.EgE.LGNLLKRKNSTIYK-LILGATNETFKELDFRRPSWSLTQELRDLTDLLKGLKENIKTLHKRDYLSITPKMEDIALVNRWIQKYNVKHFYLQVFFDKAYAISFQDILELVSNDENE..GNN..FSIER.DVKN.....QG.KTTIK...VNVKIGKEVIGKIDMPEHKAAMKELDRGRLLFYVTFEGGKGYLDNEILM----------rdvin....................................................
G2LH25_CHLTF/35-156                  ........................lnprrlr----------------------------------GSDFLMRWSQGVWSEERIVQAINDTT-EFFAIPYGPSG.AAPDKDIrSFELYFERLEKAGFGKNKRPDLLIFKNS......S-...--...---...---------------------------------------------------------.-.-.-------------------------------------------------------------------------------------------------------------------..---..-----.----.....--.-----...-----------------------------------------------------------reticdivnffgginelpfipesddkvrklldrailavece................
G2LH25_CHLTF/182-318                 ..................lglkknavlptli------------------------------------------------------------------------.-------.----------------------------......--...--...---...---------------------------------------------------------.-.-.-------------------------------------------------------------------LKEEDRKPLQEWQNMNNVPIHIWHAFYDIAFGISFSEVQKLI----NE..GFI..LPTEQ.VFQSpggviTK.KLIYK...IYYHHAYPLGSTIEEPRLQARFLEDKNGHILPYVHFEGGKMTLSEEALS----------vlrkagn..................................................
A0A554WZD2_9BURK/1-322               ..............................m---------------------------------ANSEFLTNKEQGDWAEKLVQTAINEGELGLLAVRYGRSE.SLAAGDE.GFEEFYASYQAELNEIGKRPDILIFERA......HF...PT...D--...------PDTSSDEVVSRAIAAIEVRSSSFLANRYAAYMEQRGAAALEACNRIRKEILgS.E.LADLLREKNEELYR-FLESAKNESFKQLDFRRPSWSSSAQLRRLSELLGDLKKHIAILHKRDYLSITPKVEDIALVNRWIQRFGVKHYYLQVFFDKAYLIPFEQILQIAADSKKE..GDV..FSVER.DVKN.....QG.KTTIK...INVQVGREVIGKIDMPEHRSQMKEFERGRLLFYVTFEGGRGYIDGPLLKEVLGV-----c........................................................
A0A133UIN1_9EURY/128-262             ........................krrrngk------------------------------------------------------------------------.-------.----------------------------......--...--...---...---------------------------------------------------------.-.-.--------------------------------------------------------------SLSMTVKKEDYEPLTSWREQWNVPIFVVQIFFDEAYIMPFKNIEDPVEKKEENpqTSIsgFYRRT.D-SN.....TG.KITYFadvLEFEGVERIGEFVEFPEIDARFLERDDGKVVPYVAFKEGK-------------------lnitttlenf...............................................
A0A1M6HEU2_9BACT/1-366               ...............................MTYFNDLRKITKGIPDTIVDFNIPRDKTTPPTQASSNFITNKEQGDWAEDLIFRAINETSNNFVAVRYGKSD.DLVAGEK.GFEKFYNEFQDELDNIGKRPDLLIFKKS......DF...NE...ELG...LDISGLKHTKITDYVKKAFAGLEIRSSAFLIEKYENEMQSRTKFHLSETLRIKDIIL.N.E.YSDFLNHPKKKPYLDLLKTINKNTVYAISFRRPSWNSTEKLQELTGLFKELKSHINIIQKRDYLSITPKVEDIKVVYRWAETFDVPHYYIQVFFDKSYGISFKQILKLLTDSDKE..GEY..YEISK.DIKN.....QN.KTTIK...INTRKTKQIAYKIIEPEHSSVKREMGRGRLLFYVTFKGGTAYLNIDNLRNLLNISEKDF.........................................................
J9QU37_RIEAN/1-366                   ...............................MTYYDRIRELTKTVPATLVDFGLPRDPARTPTQASSNFITNKEQGDWAENLVFRAINETSKNFVAVKYGKSD.DLVAGED.GFDTFYQEFQNELDTIGKRPDLLIFRKE......DF...NS...DLG...FDISQIPHHTITEYVKMAIAGIEVRSSAFLIDKYEEAMQVKTEKFSQIALQTRDIIL.S.E.FQEELNHPSRQAYIDLLKGITPKTLSVTDFRVPSWSSTERLSELKAHFRTLKDAIKEIQKRDYLSITPKVEDIKVVYKWIETFNVPHFYFQVFFDKVYGISFEQILAIISDSNNE..GII..FSVET.DTKN.....QN.KTTIK...INSKSGTPIALKVEEPIHESVRKEMDRGRLLFYVTFKGGTAYLDVDNLINILGIDSKEF.........................................................
A0A081BR11_9BACT/2-351               .........ykdeilelirqsllkidmdiqi--------------------------SGRPPTMASSEFLTNKEQGDWAERLVFKAINEYSEAYFAVSYGRSE.SIAAGDP.GFADFYMEYQNELNTIGKRPDILIFKIS......DF...PE...Q-Q...IDIE------NDDHIRQAVAALEVRSSSFLADKYALFMRERQQHAIDKCNQIKRTILgT.N.LGDLLQRKNETIY-QLISTATDDTFRELDFRCPSWSLTEDLRQLTALLKEMKEQIAILHKRDYLSITPKMEDIALVNRWIQRYDVKHFYLQVFFDKAYIISFKDILVLVSNDHHE..GQN..FSIER.DIKN.....QG.KTTIK...INVQIGKEVLGKIDMPEHKSAMKELDRGRLLFYVTFEGGKGYLDNDIFI----------rdvin....................................................
K7WVD9_9NOST/32-186                  ........................lnprrlr----------------------------------GSDFLMRWSQGVWSEKRLTDAINETN-QFYAIPYGPSG.TAPTDDVrAFELYFERLEAAGLGKIKRPDLLIFKIEeksyvdNF...LK...DIGg.sEELPFIVENELQSLIEKSIIAVECENSLWVAEKMPDYNK------------------.-.-.-------------------------------------------------------------------------------------------------------------------..---..-----.----.....--.-----...-----------------------------------------------------------qmkpqkrlggkmglsksavlp....................................
A0A552A3B3_MICAE/1-351               ..............................m--YKDDILNLIKQSPLEID--TEIQMTGKPPTMANSEFLTNKEQGDWAETIVFKAVNEYSGDYFAVKYGRSE.SIAAGDD.GFADFYMEYQSELNAIGKRPDILIFKVR......DF...PD...-GS...IDIEN------DQHIRQAVAAIEVRSSSFLADKYAAFMRDRQDRAIKKCEEIRQDIInT.D.LGDLLRRKNQTIY-NLMSNATDDTFRELDFRCPSWSSTKELRNLTELLKNLKENIKILHKRDYLGITPKIEDVALVNRWIQKYNVKHFYLQVFFDKAYIISFKDILALVSNDNND..GNN..FSIER.DVKN.....QG.KTTIK...INGQIGKEVLGKIDMPEHKSALKELDRGRLLFYVTFAGGKGYLDNK-------------iflrdvin.................................................
R5AUM7_9BACE/1-366                   ...............................MDYYNRIRNLASVVPTEIVDFSQPRKYSSPPTQASSDFITNKEQGDWAERLLLDAINAASRNYVAVHYGKND.DLVAGDV.GFDEFYEEFQNELDTIGKRPDILIFNKS......DF...RE...DLG...LDISRVPHDELDEYVRKAIAGIEVRSSAFLIDRYEQYMNERTEQNIAMALELKNEIL.A.K.YTALLNHPVRCRYRALLEALDRDTVHTLSFSVPGWRASADLVQLNGCLRNLKSYLKIIQKRDYLSITPKVEDLKVVYKWIENFNVPHFYFQVFFDKIYGISFERILSIISDSDNE..GCI..FSVEQ.DTKN.....HN.KTTIK...IKSSIGDVIAHKVDEPSHHSVRRELTRGRLLFHVAFNGGTAYLDVDNLISLLNIDRENF.........................................................
A0A142HF98_9BACT/1-366               ...............................MAYKDRISLLMEQIPTTLVDMEAERPPIRIPSQASSEFTTNREQGDWAENIMLAAINQTTEKYVAVRYGMGD.DRVAGEE.GFKEFFENFQREVDEIGKRPDILVFKRD......DL...PT...DWG...NDISRRPRAELDEIVPKAIVGLEVRSSAFLSKKYDEVMRERKERHTQDALAIKSRIE.T.E.YTELLNTGSRRAYLDVLAGITAETMRVIDFKRPTWRSSPQLVEAAQAFSDLKTSLEELRKRDHLSITPKIEDLRVVYHWVQTYGVPHFYVQVFFDRAYALSYEHILTLLTDPANE..ETR..YFTEG.DVKN.....QK.KMTVK...INPEEGYLLAPSVDEPDHASRRKELRRGQLLFYVTFTNGAAQLDSAALAKLLRVN----lsdl.....................................................
K9YRL1_DACSA/1-350                   ..............................m--YKEEIQNLIDKLPVEVN--TEIQLNNRPPTMANSEFLTNKEQGDWAEKIVLHAINENLKEYIAVEYGRSD.SIAAGDD.GFAEFYLEYQEELNRIGKKPDLLIFKKS......DF...PR...E-K...IDLND------ESIIQKAVAALEIRSSSFLVEQYNKFMGKRQEEAIAECLRLKTIIM.E.EpYYSLLERKNKTI-FQMLKNSTVDTFRDIDFRLPSWSVTEQLRELKELLKELKSNIKILHKRDYLSITPKVEDIALVNRWIQTYNVKHYYLQVFFDKAYLISFKNILELISNDEEE..ETN..FSIER.DVKN.....QQ.KTTIK...VNVKVGKEILGKIDMPNHTSAMKELTRGRLLFYVTFNGGKGYLDQEI------------fmkdli...................................................
K7WVD9_9NOST/181-311                 .....................ksavlptvii------------------------------------------------------------------------.-------.----------------------------......--...--...---...---------------------------------------------------------.-.-.--------------------------------------------------------------------KEEDRIPLHKWQIENKIPIHIWHVFFDKAYGLSLDQAEHLVKEGLIE..PTI..QTFQA.PGGA.....TTkKAIYK...FYYHYAYPLGISTERPTLVPNYIEDKNGHILPYVKFVGGSLQINEDALKILN-------nl.......................................................
Q30UC2_SULDN/1-366                   ...............................MTYYENIREMTKIVPVQLVNFEEPRDKARTPTQASSNFITNKEQGDWAENLIARAINETSNNFVAVKYGKSD.NLVAGED.GFDAFYQDFQNELDTIGKRPDLLIFNKV......DF...DN...SLG...FDISQEPHEEITDYVKKAIAGIEVRSSAFLIDRYEEAMQARTEKFVQIALETKDKIL.T.D.FSDVLEHPARQSYIELLNSITASTLNVADFRVPSWSSSDRLIQVKNLFKQLKNAIKEIQKRDYLSITPKVEDLKVVYKWIETFNVPHFYFQVFFDKVYGISFEQILKIISDSDND..GVI..FSVET.DTKN.....QN.KTTIK...INSKFGVPIALKVDEPLHESVRKEMDRGRLLFYVTFKGGTAYLDIENLRAILNLEESIF.........................................................
A0A1J0ABD9_9CYAN/7-170               tlsvyieniefefrndfaewssfllnprrlr----------------------------------GSDFLMRWSQGVWSEERITQAVNQHG-EFLTIPYGPSS.TAPDDDIrSFELYFERLEAAGLGKIKRPDLLVFKRE......DE...R-...---...---------------------------------------------------------.-.-.-------------------------------------------------------------------------------------------------------------------..---..-----.----.....--.-----...-----------------------------------------------------------limetlerlggiselpfiqendvnmqailsktlvgiecenslwkgqlmpdyktalrp
#=GC seq_cons                        ..............................h..................................sS-FlhphpQGsWuEphlhpAINchs.pahAlpYG.Sp.shsss-..uFt.aa.chptth.thsKRPDlLlFp.p......sh....p....................pphlppuhhulElcsS.ahht+h....t........................................................................................hh.K.EDht.l.cW.pphsV.hahhpVFFDcsYhlSFppl.tllpps.p-..s....h.hpt.shps.....pt.KhhhK...l..phuh.lh.pl-.PphtuhhhE.ppG+lL.YVpFpsGph.ls.t.............h........................................................
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