GenomeNet

Database: Pfam
Entry: SNAD4
LinkDB: SNAD4
Original site: SNAD4 
#=GF ID   SNAD4
#=GF AC   PF18750.2
#=GF DE   Secreted Novel AID/APOBEC-like Deaminase 4
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Iyer LM
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   29555751
#=GF RT   Diversification of AID/APOBEC-like deaminases in metazoa:
#=GF RT   multiplicity of clades  and widespread roles in immunity.
#=GF RA   Krishnan A, Iyer LM, Holland SJ, Boehm T, Aravind L;
#=GF RL   Proc Natl Acad Sci U S A. 2018;115:E3201.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A family of secreted AID/APOBEC like deaminases found only in
#=GF CC   sponges that often shows lineage-specific expansions [1].
#=GF SQ   74
#=GS A0A2K5LH15_CERAT/32-146   AC A0A2K5LH15.1
#=GS A0A151P4M1_ALLMI/34-150   AC A0A151P4M1.1
#=GS A0A287A3I4_PIG/32-147     AC A0A287A3I4.1
#=GS A0A151P6H5_ALLMI/36-146   AC A0A151P6H5.1
#=GS I3JAF9_ORENI/100-216      AC I3JAF9.1
#=GS A0A091EM42_FUKDA/245-366  AC A0A091EM42.1
#=GS A0A1S3FUU1_DIPOR/58-172   AC A0A1S3FUU1.1
#=GS A0A1S3FTE2_DIPOR/67-182   AC A0A1S3FTE2.1
#=GS A0A2I3LK81_PAPAN/39-159   AC A0A2I3LK81.1
#=GS A0A091EM42_FUKDA/571-686  AC A0A091EM42.1
#=GS A0A096NK44_PAPAN/50-167   AC A0A096NK44.1
#=GS A0A091IIG0_CALAN/26-138   AC A0A091IIG0.1
#=GS A0A2B4RXQ3_STYPI/35-149   AC A0A2B4RXQ3.1
#=GS ABEC3_RAT/265-378         AC P60705.1
#=GS A9QA56_FELCA/32-147       AC A9QA56.1
#=GS H2QLP9_PANTR/234-349      AC H2QLP9.2
#=GS ABC3G_MACMU/32-156        AC Q7YR23.1
#=GS R4GDA3_ANOCA/34-146       AC R4GDA3.1
#=GS H2P4E7_PONAB/39-159       AC H2P4E7.1
#=GS F6M3K4_MACMU/51-167       AC F6M3K4.1
#=GS A0A2K5JKV4_COLAP/34-149   AC A0A2K5JKV4.1
#=GS G1QB54_MYOLU/284-395      AC G1QB54.1
#=GS A0A067QK96_ZOONE/77-191   AC A0A067QK96.1
#=GS W5UL81_ICTPU/103-219      AC W5UL81.1
#=GS F1PUJ5_CANLF/40-155       AC F1PUJ5.2
#=GS H1A4Q1_TAEGU/71-187       AC H1A4Q1.1
#=GS A0A1A6GTA1_NEOLE/63-181   AC A0A1A6GTA1.1
#=GS G3PCV8_GASAC/41-157       AC G3PCV8.1
#=GS M7B9Y3_CHEMY/70-186       AC M7B9Y3.1
#=GS I3MVA8_ICTTR/25-140       AC I3MVA8.2
#=GS A0A226PW40_COLVI/168-295  AC A0A226PW40.1
#=GS F6WR88_HORSE/1-110        AC F6WR88.2
#=GS A0A1S3AN78_ERIEU/25-140   AC A0A1S3AN78.1
#=GS A0A151P7C9_ALLMI/35-150   AC A0A151P7C9.1
#=GS H0XN38_OTOGA/53-169       AC H0XN38.1
#=GS U3JXR8_FICAL/268-380      AC U3JXR8.1
#=GS A0A3M6UHR2_9CNID/67-182   AC A0A3M6UHR2.1
#=GS A0A091XJL0_OPIHO/26-138   AC A0A091XJL0.1
#=GS A0A2I3GCB3_NOMLE/58-171   AC A0A2I3GCB3.1
#=GS G1PQB2_MYOLU/35-149       AC G1PQB2.1
#=GS B5XDM8_SALSA/131-247      AC B5XDM8.1
#=GS A0A218ULD2_9PASE/33-149   AC A0A218ULD2.1
#=GS A0A2K5M2K6_CERAT/35-146   AC A0A2K5M2K6.1
#=GS ABEC3_RAT/46-167          AC P60705.1
#=GS A0A093S6Z3_9PASS/1-65     AC A0A093S6Z3.1
#=GS F6XPP0_MACMU/231-350      AC F6XPP0.2
#=GS A0A091EQ78_CORBR/26-138   AC A0A091EQ78.1
#=GS H3B7Z9_LATCH/27-142       AC H3B7Z9.1
#=GS F6PKH9_ORNAN/39-155       AC F6PKH9.1
#=GS A0A0D9R289_CHLSB/231-347  AC A0A0D9R289.1
#=GS A0A093PWR2_9PASS/26-138   AC A0A093PWR2.1
#=GS A0A2B4RM68_STYPI/116-235  AC A0A2B4RM68.1
#=GS A0A286XNR2_CAVPO/40-155   AC A0A286XNR2.1
#=GS A0A0Q3WRD0_AMAAE/94-210   AC A0A0Q3WRD0.1
#=GS H2QLP9_PANTR/40-163       AC H2QLP9.2
#=GS A0A1D5QUT6_MACMU/55-171   AC A0A1D5QUT6.1
#=GS F7IF99_CALJA/27-139       AC F7IF99.2
#=GS K7G199_PELSI/40-156       AC K7G199.1
#=GS G1Q326_MYOLU/43-159       AC G1Q326.1
#=GS A0A1V4JAP2_PATFA/33-149   AC A0A1V4JAP2.1
#=GS A0A1L8FIE3_XENLA/30-148   AC A0A1L8FIE3.1
#=GS A0A2Y9QZB6_TRIMA/160-253  AC A0A2Y9QZB6.1
#=GS F7EWS7_RAT/249-362        AC F7EWS7.1
#=GS U3JXR8_FICAL/25-141       AC U3JXR8.1
#=GS H9GWR3_CANLF/65-169       AC H9GWR3.2
#=GS A0A1D5QGX2_MACMU/52-166   AC A0A1D5QGX2.1
#=GS F1SLW4_PIG/40-155         AC F1SLW4.2
#=GS G3WLB3_SARHA/68-195       AC G3WLB3.1
#=GS G1TLT9_RABIT/38-161       AC G1TLT9.2
#=GS A0A093GVH6_DRYPU/26-138   AC A0A093GVH6.1
#=GS A0A2K5IT20_COLAP/34-149   AC A0A2K5IT20.1
#=GS ABC3G_PAPAN/41-163        AC Q694B7.1
#=GS G5AYU4_HETGA/37-157       AC G5AYU4.1
#=GS A0A2I3TLS9_PANTR/60-171   AC A0A2I3TLS9.1
A0A2K5LH15_CERAT/32-146              ..........................................y-QLTPQNGS..TPI-RGHL.KN....KKN.........-HAEIRFINKIKS.....MGL.D...........ET.QC...........YQVTCYLTWSPC....PS....CARELVDFI...K....A...HR.....H..L...N.L..RIFASRL...Y...yH.....................W.RPH......YQE..GLLLL..CGS..Q....VPV..EVM.........GLP...E.FSDCWEN......................................................
A0A151P4M1_ALLMI/34-150              ........................................yiv---ETQGKE..SGTIRGYL.ED....EHA........aAHAEDAFFNTILP.....-EC.E...........SS.LR...........YNVTWYVSSSPC....VA....CAERIAEIL...K....K...NK.....N..L...R.L..AILVSRL...F....M.....................W.EEP......EMQ.aVLKKM..KAA..G....CKL..RIM.........KPQ...D.FEYVWQN......................................................
A0A287A3I4_PIG/32-147                .........................................yq--VKGPDDS..-ILDKGCF.QN....KKK.........RHAEIRFIDKINS.....LNL.D...........QN.QC...........YRIICYVTWSPC....HN....CAKELVDFI...S....N...RH.....H..L...S.L..QLFASRL...Y...fH.....................W.VRC......YQR..GLQRL..QAN..R....VSV..AVM.........KGP...E.FKDCWEK......................................................
A0A151P6H5_ALLMI/36-146              ..................................seltwggrp---------..---YKHWY.EN....TEH.........CHAEIHFLENFS-.....---.S...........KN.GS...........CIITWYLSWSPC....AE....CSARIADFM...K....E...NT.....N..V...K.L..NIHVARL...Y...lH.....................D.DKH......TRQ..GLRYL..MKM.kR....VTI..QIM.........TIP...D.YKYCWNT......................................................
I3JAF9_ORENI/100-216                 ........................................ylv---DKGNTS..DGLLRGYL.ED....EHA........gTHAEEAFFTQCLP.....-HC.N...........PA.LK...........YTVTWYVSSSPC....SA....CAAKIAELL...K....D...QK.....N..L...K.L..NIFAARL...F....E.....................W.EEG......EIQ.aGLRTL..HAA..G....CKL..RVM.........KPL...D.FSYTWDT......................................................
A0A091EM42_FUKDA/245-366             ...........................................YTIESKKKN..RFLRNGVF.QN....QDHpy.....trLHAELRFLSWFHD.....NWL.C...........PG.NS...........YQVTLYMSWSPC....SE....CAEELTTFL...A....G...HR.....N..V...T.L..TIFFSKL...Yc..cD.....................P.DSP......HRE..GLKTL..AAG..G....ARL..FVM.........FDT...D.FSYCWTN......................................................
A0A1S3FUU1_DIPOR/58-172              ........................................crv---ERQQEG..-LIDTRVF.KN....QGI.........-HAELCFLHWFHD.....EEF.F...........PG.ED...........YQLTWYMSWSPC....PD....CAEQVAQFL...A....T...HR.....N..V...S.L..TIFIARL...Y...yH.....................W.LPQ......FQQ..GLRRL..CQE..G....AQV..EVM.........SYQ...E.FEDCYE-e.....................................................
A0A1S3FTE2_DIPOR/67-182              ...........................................YQITWSSHK..-VW-RETA.KN....TVD.........SHVEVNFIQNLTA....gRYC.R...........PS.TR...........CSILWFLSWSPC....SS....CSKAIRLFL...S....Q...HP.....G..V...S.L..VIYVARL...F...qH.....................M.DPQ......NRQ..GLREL..IHS..G....VTI..QVM.........RPQ...E.YDYCWKN......................................................
A0A2I3LK81_PAPAN/39-159              ..........................................v-EVIKQRST..VSWERGVF.QN....QVDpk.....shCHAERCFLSWFCE.....DIL.S...........PN.TD...........YQVTWYTSWSPC....PE....CAGEVAEFL...A....R...HN.....N..V...M.L..TIYTARL...Y...yS.....................Q.DPN......YQQ..GLRSL..SEK..G....VSV..KIM.........DYE...D.FKYCWEK......................................................
A0A091EM42_FUKDA/571-686             ...........................................YQVQKANGN..-LLTKGCL.RT....KKG.........YHAESRFIKRICS.....LGL.D...........QA.QS...........YQVTCFLTWSPC....PR....CAQELVLFK...S....S...HP.....H..L...Y.L..RIFTARL...Y...fH.....................W.RKS......YQE..GLQRL..CRA..Q....VPV..AVM.........GYP...E.FAHCWY-n.....................................................
A0A096NK44_PAPAN/50-167              ...............................pmderrgflhnk---------..---AKNVL.RG....DYG.........CHAELCFLGEVPS.....WQL.D...........PA.QT...........YRVTWFISWSPC....LRr..gCAEQVRAFL...Q....E...NT.....H..V...R.L..HIFAARI...Y....D.....................F.DFL......YQE..ALRTL..RDA..G....AQV..SIM.........TYE...E.FKHCWDT......................................................
A0A091IIG0_CALAN/26-138              ...........................................YEIRWRRGT..-IW-RNWC.SN....EFP.........QHAEDNFFQNR--.....FNA.V...........PS.VS...........CSITWFLSTTPC....GR....CSKRILEFL...R....L...HP.....N..V...T.L..KIYAARL...F...rH.....................L.DNR......NRQ..GLRKL..ASN..G....VII..QIM.........GLP...D.YSYSWKK......................................................
A0A2B4RXQ3_STYPI/35-149              ..........................................v-SIKAKDGK..PIFGKRFK.NR....YPE.........-HAEIIMLRNSNF....sDVV.E...........KN.HD...........IDITLTLNYSPC....SS....CACILKEFY...V....N...NS.....N..I...KcF..TIQFSFI...Y...yK.....................E.DMK......NKT..GLQNL..EEA..G....VTL..QAM.........NAE...S.W------rev...................................................
ABEC3_RAT/265-378                    ...........................................YQLEQFNGQ..APL-KGCL.LS...eKGK.........QHAEILFLDKIRS.....MEL.S...........--.-Q...........VIITCYLTWSPC....PN....CAWQLAAFK...R....D...RP.....D..L...I.L..HIYTSRL...Y...fH.....................W.KRP......FQK..GLCSL..WQS..G....ILV..DVM.........DLP...Q.FTDCWTN......................................................
A9QA56_FELCA/32-147                  ..........................................y-QLKLPEGT..-LIHKDCL.RN....KKK.........RHAEMCFIDKIKA.....LTR.D...........TS.QR...........FEIICYITWSPC....PF....CAEELVAFV...K....D...NP.....H..L...S.L..RIFASRL...Y...vH.....................W.RWK......YQQ..GLRHL..HAS..G....IPV..AVM.........SLP...E.FEDCWRN......................................................
H2QLP9_PANTR/234-349                 .......................llnqrrgflcnqaphkhgfl---------..--------.--....--E........gRHAELCFLDVIPF.....WKL.D...........LH.QD...........YRVTCFTSWSPC....FS....CAQEMAKFI...S....N...NK.....H..V...S.L..CIFAARI...Y....D.....................D.QGR......CQE..GLRTL..AKA..G....AKI..SIM.........TYS...E.FKHCWDT......................................................
ABC3G_MACMU/32-156                   .............................vktkdpsgppldak---------..-IFQGKVY.SK....AKY.........-HPEMRFLRWFHK....wRQL.H...........HD.QE...........YKVTWYVSWSPC....TR....CANSVATFL...A....K...DP.....K..V...T.L..TIFVARL...Y...yF.....................W.KPD......YQQ..ALRIL..CQK..RggphATM..KIM.........NYN...E.FQDCWNK......................................................
R4GDA3_ANOCA/34-146                  ...........................................YEIHWDNNT..---SRNWC.TN....KPG.........LHAEENFLQIFNE....kIDI.R...........QD.TP...........CSITWFLSWSPC....YP....CSQAIIKFL...E....A...HP.....N..V...S.L..EIKAARL...Y...mH.....................Q.IDC......NKE..GLRNL..GRN..-....-RV..SIM.........NLP...D.YRHCWTT......................................................
H2P4E7_PONAB/39-159                  ....................................vkirkdp-------SK..LAWDTGVF.RGqvysQPE.........HHAEMCFLSWFCG.....NQL.S...........AY.ER...........FQITWFVSWTPC....PD....CVAKLAEFL...A....E...HP.....N..V...T.L..TVSAARL...Y...yY.....................W.ERG......YRR..ALRRL..RQA..G....AHV..KIM.........DYE...E.FAYCWEN......................................................
F6M3K4_MACMU/51-167                  ...........................mderrgflcnkaknvp---------..--------.--....--Cgd.....ygCHVELRFLCEVPS.....WQL.D...........PA.QT...........YRVTWFISWSPC....FRr..gCAGQVRVFL...Q....E...NK.....H..V...R.L..RIFAARI...Y....D.....................Y.DPL......YQE..ALRTL..RDA..G....AQV..SIM.........TYE...E.FKHCWDT......................................................
A0A2K5JKV4_COLAP/34-149              ...........................................YEIKWGMSQ..KIW-RSSG.KN....TTN.........-HVEVNFIEKLTS....eRRF.H...........SS.VS...........CSITWFLSWSPC....WE....CSQAIREFL...S....Q...HP.....G..V...T.L..VIYVARL...F...wH.....................T.DQQ......NRQ..GLRDL..VNS..G....VTI..QMM.........TAS...E.YYHCWRN......................................................
G1QB54_MYOLU/284-395                 ...........................kinegrdqpqgadthw---------..--------.--....EP-.........RHAELCFQDRVRS.....WHL.D...........EG.KQ...........YRLTCYISWSPC....PD....CAQKLVEFL...G....E...NS.....H..V...R.L..RIFAARI...Y....K.....................K.RDR......YKH..WLRQL..RDA..G....AQL..TIM.........TLN...E.LQHCWV-t.....................................................
A0A067QK96_ZOONE/77-191              ....................................fnetata--------E..QFWEISY-.SH....LPG.........PHAEIKVLRNIKA.....REL.C...........LG.YR..........tRIVTLFLSYSPC....AN....CANFIIEFS...R....T...RP.....Q..C...T.V..YIRFTCL...F...rH.....................P.EEI......HRD..GLRRL..NAE.pG....ISL..GVF.........TVY...E.W------rrla..................................................
W5UL81_ICTPU/103-219                 ..................................nevrgpgde---------..-AILRGYV.ED....EHVg.......gDHAEDAFFRLVLP.....-HY.D...........VS.TR...........YTVTWYVSSSPC....SS....CASKLAEIL...R....E...RQ.....T..L...R.L..TIFSARL...F....E.....................W.EEP.....eVRA..GLKAL..AGA..G....CKL..RMM.........KPL...D.FSYTWDT......................................................
F1PUJ5_CANLF/40-155                  ...........................................YEIQWGTSH..KTW-RNSG.KN....TTN.........-HVEINFMEKFAA....eRQY.C...........PS.IR...........CSITWFLSWSPC....WE....CSNAIRGFL...S....Q...HP.....S..V...T.L..VIYVARL...F...wH.....................T.DPQ......NRQ..GLRDL..INS..G....VTI..QIM.........TVP...E.YDHCWRN......................................................
H1A4Q1_TAEGU/71-187                  ..........................................y-VVETQGKE..PVTSRGYL.ED....EHA........aAHAEMAFFNTILP.....-TC.Q...........AG.AR...........HDVTWYVSSSPC....VT....CAQRICEAL...R....K...NK.....G..L...R.L..TIMVGRL...F....M.....................W.EEP......EMQ.aALRSM..KEA..G....CKL..RIM.........KPQ...D.FEYVWKN......................................................
A0A1A6GTA1_NEOLE/63-181              ...............................hfknlsxancrn---------..----NTFL.CY....EDD.........FHAEECFLNWFHAq..vlEVL.S...........PS.EE...........YKITWYVSWSPC....SK....CAELVARFL...A....T...HR.....K..L...S.L..AIFSSRL...Y...yF.....................W.DPH......YQH..RLRRL..FQA..G....AQI..SVM.........DFP...E.FEKCWNK......................................................
G3PCV8_GASAC/41-157                  .......................................ylvd----KGNTD..DGLLRGYL.ED....EHS........gSHAEEAFFIQCIP.....-NY.D...........PS.VR...........YTVTWYVSSSPC....AA....CAAKIAEVL...K....A...RK.....N..I...K.L..SIFAARL...F...eC.....................E.ETD......IQA..GLKAM..HTA..G....CKL..RVM.........KPL...D.FSYTWDT......................................................
M7B9Y3_CHEMY/70-186                  ....................................yvveiqg-------KE..PGSFQGYL.ED....EHA........aAHAEDAFFNNILP.....-TC.D...........PN.LR...........YNVTWYVSSSPC....VP....CADRIAQVL...Q....K...NK.....N..L...R.L..SILVSRL...F....M.....................W.EEP......EMQ.aALKKL..KAS..G....CKL..KIM.........KPQ...D.FEYIWQN......................................................
I3MVA8_ICTTR/25-140                  ...........................................YEIQWGTSR..KIW-RNSS.KN....TTN.........-HVEVNFIEKFTA....eRHF.C...........PS.IS...........CSITWFLSWSPC....WE....CSKAIREFL...S....Q...HP.....N..M...T.L..VIYTARL...F...qH.....................M.DQQ......NRQ..GLRDL..INS..G....VTI..QMM.........TVS...S.LPPC---lki...................................................
A0A226PW40_COLVI/168-295             ...........................................YELRSSSGR..-VVQKGHA.SS....CAEq.......dSHPESILFEAD--.....GYL.D...........TV.THac......gniGRITLYSHYSPC....NEafhcCISKMYNFL...L....K...HP.....K..T...T.L..CLCFSRL...Y....Haed...............gfpT.AMW......NRQ..ALLSL..ASL..W....PRVtlQLL.........TME...-.---IW--wn....................................................
F6WR88_HORSE/1-110                   ......................................mshni---------..--W-RYSG.KN....TT-.........KHVEINFIEKFTS....eRHL.R...........PS.IS...........CSIVWFLSWSPC....WE....CSKAIREFL...S....Q...HP.....N..V...T.L..VIYVARL...F...qH.....................M.DRL......NRQ..GLRDL..INS..G....VTI..QIM.........RTS...E.YDHCWRN......................................................
A0A1S3AN78_ERIEU/25-140              ...........................................YEVRWGSSR..NAW-RSTA.RN....TTR.........-HAEVNFLERFAA....eRHF.D...........KP.VS...........CSITWFLSWSPC....WE....CSQAIGAFL...S....Q...HP.....Q..V...T.L..AIHVTRL...F...hH.....................E.DEQ......NRQ..GLRDL..LAR..G....VTL..QVM.........GDS...E.YAHCWRT......................................................
A0A151P7C9_ALLMI/35-150              ...........................................CEIKWGKYG..KPW-LHWC.QN....QRM........nIHAEDYFMNNIFK.....AKK.H...........-P.VH...........CYVTWYLSWSPC....AD....CASKIVKFL...E....E...RP.....Y..L...K.L..TIYVAQL...Y...yH.....................T.EEE......NRK..GLRLL..RSK..K....VII..RVM.........DIS...D.YNYCWK-v.....................................................
H0XN38_OTOGA/53-169                  ........................qyrgflqsqnnccrygdga---------..--------.-G....CPP.........LHAEFCFLDRVGS.....WQL.N...........PN.WH...........YRVTCFISWSPC....FS....CAQKVAMFL...R....R...NS.....H..V...K.L..RILAARI...Y....D.....................Y.HPG......YEE..GLKAL..QGT..G....AQV..AIM.........THA...E.FEHCWDT......................................................
U3JXR8_FICAL/268-380                 ...........................................YEIRWKGGS..-IW-RNWC.SN....NPE.........QHAEINFLENR--.....FND.R...........PQ.TS...........CSITWFLSTSPC....GK....CSKRILEFL...R....S...HP.....N..V...T.L..KIYTAKL...F...rH.....................Y.EIR......NRQ..GLRNL..IMN..G....VAV..HIM.........NLE...D.YSYCWTN......................................................
A0A3M6UHR2_9CNID/67-182              ........................................atm---KSSYGE..GIFNKRFV.NI....PSI.........KDAEAVMLCDDDF....dDAV.T...........AH.HD...........IEITLTLNYSPC....SK....CADKLRDFY...E....N...HR.....N..I..rN.L..IIQFSFL...Y...rI.....................R.EEK......NQF..GLRNL..REA..G....VTL..QAM.........NAN...S.W------rev...................................................
A0A091XJL0_OPIHO/26-138              ...........................................YEIRWSRGT..-IW-RNWC.TN....NST.........QHAEVNFLENC--.....FKA.M...........PS.VS...........CSITWVLSTTPC....GK....CSKRIQDFL...R....I...YP.....N..V...T.L..EIHAAKL...F...kH.....................L.DTR......NRE..GLRNL..AKD..G....VII..HIM.........NLA...D.YSYWWK-r.....................................................
A0A2I3GCB3_NOMLE/58-171              ................................qvlpkfqsnhr---------..----QEVY.FQ....LE-.........NHAEMCFLSWFCG.....NQL.P...........AN.RR...........FQITWFVSWNPC....LP....CVAKVTEFL...A....E...HP.....N..V...T.L..TISAARL...Y...yY.....................R.GRD......WRR..ALRRL..HKA..G....ARV..KIM.........DYE...D.FAYCWEN......................................................
G1PQB2_MYOLU/35-149                  ..............................eelqgflrnqges---------..-----QGA.QN....CVL.........RHAELCFLHGVRS.....WHL.D...........EG.KQ...........YRLTWHISWSPC....PD....CASKLVEFL...G....E...NS.....H..V...S.L..RIFAARI...H....T.....................K.YRG......YED..GLRQL..QDA..V....DHL..TIM.........TLK...E.LQHCWV-t.....................................................
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ABEC3_RAT/46-167                     ......................................yevtr-----KDCDspVSLHHGVF.KN....KDN.........IHAEICFLYWFHDk..vlKVL.S...........PR.EE...........FKITWYMSWSPC....FE....CAEQVLRFL...A....T...HH.....N..L...S.L..DIFSSRL...Y...nI.....................R.DPE......NQQ..NLCRL..VQE..G....AQV..AAM.........DLY...E.FKKCWKK......................................................
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H3B7Z9_LATCH/27-142                  .........................................fs--LQQENKT..LWNLWGYA.HN...nQDT.........SHAEILVLREIEK.....YLL.Eka.......sdHE.IR...........QRVTLYVTCSPC....NR....CCTKILEFF...Q....R...FQ.....R..F...D.M..DIKISKI...Y....-.....................-.D--......-LD..SLQDL..KQL..G....VSL..KVM.........DSS...D.FKECFD-l.....................................................
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A0A0D9R289_CHLSB/231-347             ..............................mdqhwgflcnqar---------..-----NPL.HG....VDS.........CHVELCFLSQVSS.....WQL.D...........PA.QT...........YRVTWFISWSPC....FSg..gCAEQVRAFL...Q....E...NT.....H..V...R.L..CIFAARI...Y....N.....................Y.DPL......YQE..ALRML..RDA..G....AQV..SIM.........TYE...E.FEYCWDT......................................................
A0A093PWR2_9PASS/26-138              ...........................................YEIRWRNGS..-IW-RNWF.SN....NRN.........QHAEVNFLENCFS.....--D.V...........PP.AP...........CSITWFLSTSPC....GK....CSRRILEFL...R....T...HR.....N..V...T.L..EIYAAKL...F...rH.....................Q.DIR......NRQ..GLCNL..VMN..G....VTI..HIM.........NLA...D.YSYCWK-r.....................................................
A0A2B4RM68_STYPI/116-235             ..........................................a-TIKNNDQE..VIFNKRFE.TT....PRK.........KHVEAKLLDDSEF....vNIV.A...........EH.FG...........IEIILTINYSPC....GD....CADKLISFY...E....K...EE....nK..A...K.I..QKFIIQFsscY....Kt...................dT.LKK......NKD..GLIKL..DKA..G....ITL..LSM.........KEE...S.WK-----ev....................................................
A0A286XNR2_CAVPO/40-155              ..........................................s-EVRWGASP..RTWRESS-.LN....TTS.........-HVEINFIEKFTS....gRSL.R...........PA.VR...........CSMTWFLSWSPC....WE....CARAIREFL...H....Q...HP.....N..V...S.L..VIYVARL...Y...wH.....................V.DEQ......NRQ..GLRDL..VTS..G....VRV..QIM.........SDS...E.YRHCWRN......................................................
A0A0Q3WRD0_AMAAE/94-210              .........................................ci--LRWGETG..TPW-SHWV.KN....YRY.........-HAEVYFLEKIFQ....tRKS.S...........KN.IN...........CSITWYLSWSPC....AK....CCRKILNFL...K....K...HS.....Y..V...S.I..KIHVARL...F...rI.....................D.DKE......TXQ..NLKNL..GSL.vG....VTV..SVM.........EXE...D.YTNCWKT......................................................
H2QLP9_PANTR/40-163                  ..............................ktkgpsrppldak---------..-IFRGQVY.SK....LKY.........-HPEMRFFHWFSK....wRKL.H...........RD.QE...........YEVTWYISWSPC....TK....CTRDVATFL...A....E...DP.....K..V...T.L..TIFVARL...Y...yF.....................W.DPD......YQE..ALRSL..CQK..RdgprATM..KIM.........NYD...E.FQHCWSK......................................................
A0A1D5QUT6_MACMU/55-171              ................................mdqhwgflcnq---------..---AKNVL.RG....DYG.........CHAELCFLGWVPS.....WQL.D...........PA.QT...........YRVTWFISWSPC....FSw..gCAEQVRAFL...Q....E...NT.....H..V...R.L..HIFAARI...Y....D.....................Y.DPL......YQE..ALRTL..RDA..G....AQV..SIM.........TYD...E.FEYCWDT......................................................
F7IF99_CALJA/27-139                  ........................................yql---MPQNGS..TPT-RGYF.KN....KNN.........RHAEICFIDKIES.....TGL.D...........KT.QC...........YEVTCYLTWSPC....PS....CAQKLVAFA...K....A...QV.....H..L...N.L..RIFASRL...Y...yH.....................W.LLS......CKK..GLQLL..WQS..Q....IPV..EVM.........GLP...D.-------srgt..................................................
K7G199_PELSI/40-156                  ...........................................YEVKWSNSR..KLT-QRCC.HS....TRT.........EHAEIYFLEDVFH....rQRY.D...........PS.DH...........CSLTWYMSWSPC....GE....CCKAIRDFL...K....E...QP.....N..V...N.L..VIYVARI...Y...cH.....................E.EEN......NRQ..GLRSL..VNI..G....VTI..RIM.........DLP...V.YSYCWRT......................................................
G1Q326_MYOLU/43-159                  ................................awvpakehegf---------..--LRNEAL.SS....LSPv.......lRHAELCFLRGVSD.....WDL.D...........EG.KQ...........YRLT-YMSWSPC....PN....CAPKLVEFL...D....E...NS.....H..V...T.L..RIFPARI...H....T.....................K.SRG......YQD..GLRNL..RDA..G....AQL..AIM.........TLK...E.HQHCWDT......................................................
A0A1V4JAP2_PATFA/33-149              ..........................................c-KLQWGDTG..RSW-IHWI.RK....DRY.........-HAEVYFLEKIFK....mRRS.K...........NY.VN...........CSITWYLSWSPC....VR....CCCEILNFL...E....K...HS.....Y..V...N.I..DIYVARL...Y...kI.....................Q.NSE......VRE..GLKKL..VSS.kK....VTI..AVM.........EIK...D.YTYCWKN......................................................
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A0A2Y9QZB6_TRIMA/160-253             ....................................lleggrg---------..--------.--....---.........----------FLN.....NQL.D...........PA.QC...........YRVNCFMSRRPC....FL....CAWEVATFL...G....R...NS.....H..V...S.L..HIFTSCT...Ye..yF.....................P.SSE......CKH..-----..---..-....---..---.........---...-.-------ywrtfvdnqgcpfepwnrldknsqtiw...........................
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H9GWR3_CANLF/65-169                  ...............................gqrarvvwgggg---------..--------.--....---.........QHAEWFLLEHIRS.....RNL.D...........QK.LS...........YKVTCFLSWTPC....EK....CAEEIIRFL...A....K...NR.....H..V...S.L..SILASRI...Y....T.....................-.MGP......YVK..GLREL..YDA..G....VHI..SIM.........TFR...D.FEYCWQT......................................................
A0A1D5QGX2_MACMU/52-166              .........................lqslyrqelshwdyrcpp---------..--------.--....-PC.........HHAEMCFLSRFCG.....NQL.P...........AY.KR...........FQITWFVSWTPC....TD....CVAKVAEFL...A....E...HP.....N..V...T.L..TISAARL...Y...yY.....................W.ETD......YRR..ALCRL..RQA..G....ARV..KIM.........DSE...E.FAYCWEN......................................................
F1SLW4_PIG/40-155                    ...........................................YELQWGRSR..DTW-RHTG.KN....TTN.........-HVERNFLAKITS....eRHF.H...........PS.VH...........CSIVWFLSWSPC....WE....CSEAIREFL...D....Q...HP.....S..V...T.L..VIYVARL...F...qH.....................M.DPQ......NRQ..GLRDL..VNH..G....VTI..QIM.........GAP...E.YDYCWRN......................................................
G3WLB3_SARHA/68-195                  ...........................................YELKTSSGS..-LVQKGHA.SG....CSEy.......dTHPESMLFEMDSY.....--L.E...........AV.IRnn......dniEHVFLYSNYCPC....NEanhcCISKMYNFL...M....R...YP.....A..I...S.L..NIYFSQL...Y....Htet...............nfpV.SAW......NRE..ALRSL..ASL..W....PQV..TV-.........---...-.-------npmsggiwhy............................................
G1TLT9_RABIT/38-161                  ...................................yevqlldg--------S..-SQHQGFL.RN....KNFcidfdpslrRHAELCFLDLVPA.....WRL.D...........PA.QH...........YRVTWFISWSPC....FL....CAQAVAEFL...R....R...NA.....H..V...S.L..RIFAARI...Y....T.....................W.RTD......YKA..GLQDL..QRA..G....AQI..AIM.........TPA...E.IQFCWNT......................................................
A0A093GVH6_DRYPU/26-138              ...........................................YEIRWSRGS..-IW-RNWC.SN....SST.........QHAEVNFLENC--.....FKA.M...........PS.VS...........CSITWFLSTTPC....GN....CSRRILEFL...R....A...HP.....K..V...T.L..AIHAAKL...F...kH.....................L.DVR......NRH..GLKAL..ATD..G....VVL..HIM.........SIA...D.YRYCWTK......................................................
A0A2K5IT20_COLAP/34-149              ...................................meiikqcs--------T..GVF-RNQV.DP....ETH.........CHAERCFLSWFCK.....DIL.S...........PN.TN...........YQVTWYTSWSPC....LD....CAGEVAEFL...A....R...HS.....N..T...K.L..AIFAARL...Y...yF.....................W.DTD......YQQ..GLCSL..SEE..G....ASV..EIM.........GYE...D.FKYCWEN......................................................
ABC3G_PAPAN/41-163                   ...............................trgpsmptwdak---------..-IFRGQVY.SK....AK-.........YHPEMRFLHWFRK....wRQL.H...........RD.QE...........YEVTWYVSWSPC....TG....CANSVATFL...A....E...DP.....K..V...T.L..TIFVARL...Y...yF.....................W.KPD......YQE..ALRVL..CQK..RgsphATM..KIM.........NYN...E.FQHCWNK......................................................
G5AYU4_HETGA/37-157                  ...........................................YEVKRERDN..KVLHKGVV.QN....QVTss.....llSRTELSFISCFHA.....TEL.C...........LD.ET...........YKVTWYISWSPC....VE....CAEEIVKFL...A....N...HR.....N..V...F.L..TVFIARL...Y...yY.....................R.EHT......FKE..GLQAL..DNG..G....VQM..HMM.........CLQ...D.FKDCWS-l.....................................................
A0A2I3TLS9_PANTR/60-171              ....................................lpklqsn---------..---HRQEV.DP....ETH.........CHAERCFLSWFCD.....DIL.S...........PN.TN...........YQVTWYTSWSPC....PE....CAREVAEFL...A....R...HS.....N..V...K.L..TIFTARL...Y...hF.....................W.NTD......YQE..GLCSL..SQE..G....ASV..KIM.........SYK...D.FVSCWKN......................................................
#=GC seq_cons                        ..................................................tt....h.pthh.ps....ppt.........tHAEhsFLpphts.....hph.c...........ss.tp...........hplTWalSWSPC....sp....CApcltcFL...p....p...cs.....p..V...s.L..sIasARL...Y....p.....................h.ctp.......pp..GL+pL..tps..G....spl..plM.........shp...-.apaCWps......................................................
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