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Database: Pfam
Entry: Spc29
LinkDB: Spc29
Original site: Spc29 
#=GF ID   Spc29
#=GF AC   PF17082.6
#=GF DE   Spindle Pole Component 29
#=GF AU   Llagostera M;0000-0001-8177-8321
#=GF SE   Manual
#=GF GA   31.00 31.00;
#=GF TC   31.10 33.00;
#=GF NC   30.90 30.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10339566
#=GF RT   Spc29p is a component of the Spc110p subcomplex and is essential
#=GF RT   for spindle pole body duplication.
#=GF RA   Elliott S, Knop M, Schlenstedt G, Schiebel E;
#=GF RL   Proc Natl Acad Sci U S A. 1999;96:6205-6210.
#=GF DR   INTERPRO; IPR031392;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Spc29 is a component of the Spc-110 subcomplex and is required
#=GF CC   for the SPB (Spindle pole body) duplication. Spc29 acts as a
#=GF CC   linker between the central plaque component Spc42 to the inner
#=GF CC   plaque component Spc110 [1].
#=GF SQ   19
#=GS SPC29_CANGA/1-230       AC Q6FP43.1
#=GS W0T6M5_KLUMD/1-292      AC W0T6M5.1
#=GS S6EKF4_ZYGB2/5-63       AC S6EKF4.1
#=GS A0A1G4MHM1_LACFM/1-226  AC A0A1G4MHM1.1
#=GS H2AZC5_KAZAF/8-226      AC H2AZC5.1
#=GS A0A1G4KMP4_9SACH/5-221  AC A0A1G4KMP4.1
#=GS A0A1G4J6E8_9SACH/4-208  AC A0A1G4J6E8.1
#=GS SPC29_ASHGO/55-290      AC Q75BW4.1
#=GS J7SAJ3_KAZNA/11-172     AC J7SAJ3.1
#=GS SPC29_KLULA/1-272       AC Q6CRT5.1
#=GS J6EDL3_SACK1/1-251      AC J6EDL3.1
#=GS A0A0X8HWD7_9SACH/1-247  AC A0A0X8HWD7.1
#=GS SPC29_YEAST/1-251       AC P33419.1
#=GS G8JXL1_ERECY/1-257      AC G8JXL1.1
#=GS A7TKY7_VANPO/6-246      AC A7TKY7.1
#=GS A0A1G4IZT6_9SACH/5-213  AC A0A1G4IZT6.1
#=GS A0A0C7N8A2_9SACH/8-227  AC A0A0C7N8A2.1
#=GS C5DXL9_ZYGRC/5-46       AC C5DXL9.1
#=GS C5DEV0_LACTC/5-214      AC C5DEV0.1
SPC29_CANGA/1-230                  .........MVVGPISNLRDDALKDDTLNHIRKEYLESKKQISNL.LSQETN..TN...EFSRKPypnsSPI...RKFDHFANE..................---------RPTTIDAKLREQLRTGASDV.....---AIEQ.SL......RT.NSDESR.....NQMI.....Y..DD..MKV--.-MKR.....IIDGQQESIRELRRALEQERYMNSELQRKYNEMERRF.........DRLEW.FINSHDK..............FQ.AYQ............................DIRSNTTKKDFSDPIFNNGLKRR........WDEYPIRSF......EPDT...NI.---NRNN..RIFSNYDDSTTRLMQITDPHY..........
W0T6M5_KLUMD/1-292                 .........MDVSQFLNNVEN---DDTLQNIRKEYLNSKRTLQEL.MSNQSP..TKr.mEFSKRP....TAApdlRK-DNNSDAnkkynn......ifhnspKANQFKRPSGNINEDEFLRIQLREAMAKS.....KEPKQSI.PS......GN.------.....IDKL.....-..SS..LTRLD.DLEK.....RLYQHELQIQTLKSELYQSNSLNRSLQQKVNLLEEHM.........KMISG.NSYL-GK..............TV.STAndaqvpvnvklsgipnsiyngnyldrpqSAPSTSSTSDWMRNALTDVDDTKvllglkkpLDRPENDSIshfsnnHNGN...NEiPLFQNQR..RNLSNFDDSTSRLINITGN--rr........
S6EKF4_ZYGB2/5-63                  ......tre-----FFERPEN---DDTLQNIRRQYLESKRNLQDL.MMKQGDeeTKirtEFVSS-....---...---------..................-----------------------------.....-------.--......--.------.....----.....-..--..-----.----.....-------------------------------------.........-----.-------..............--.---............................-----------------------........---------......----...--.-------..---------------------skpprepekk
A0A1G4MHM1_LACFM/1-226             mnhssargl------RNMPEA---DDTLHKIRRDYLMSKKNLQEL.LTASST..--...RLSGNS....ARI...GP-------..................-LPTPPLQSSEALSDEKLRQQIRQGLQKD.....-EPPLRS.PQ......AS.------.....LQHM.....T..SS..ADL-A.YLRQ.....LMRDQQRQIDDLTRRLHSQSVSNKALQDRVTMLEDYV.........---SQ.MEASNRQ..............TR.KYNyn.......................ytkS-----ALSSSSSLGRSTAPSES........YDAYTGPEL......DNTNyllDL.TPGKIQH..RDFSNLDDSTTRLLQLAQ---nah.......
H2AZC5_KAZAF/8-226                 .......tk----DFFNRAST---QDSLRDIMKESEEIMKRNGSL.----QD..TT...VFNRSK....DKL...LY---GKND..................--GYNDRLQTDSLLDDKLRQQLR-GNAPL.....PSSRIPS.AStllennRS.NSQRSNdmekiIDFM.....Y..KS..SNEIK.LLKQ.....TVHDQSLELKNLKNELGLQRQENLNLNFKIKDLDRTIrv.....ndRDLPY.LENNQRSssanlnyepnrslsFR.NYS............................DRFNDTRFQEYPRN-YEEEDT--........---------......----...--.-------..---------------------kkllntr...
A0A1G4KMP4_9SACH/5-221             .....katg-----FFNDPET---DDTLQNIRREYLASKKNLQEL.------..--...-LVTSP....TGT...RT--RPVQVp...............tpPTDGPLFNRSYSN-DDRLRQQLREGLQHE.....--APVSA.SS......FR.SLPRN-.....--PV.....P..KH..YNEDD.NLRR.....MVYDQQRQIDQLQRGLDTQGARNLALQDRLYVLERTI.........SKLEA.-ELS---..............-K.ARP............................HTPHIDQAADHLPSRFAQAQDFQ........DSENTR-VL......LNLD...SE.---KPAK..RQISNYDDSTTKLLQLAQN--sn........
A0A1G4J6E8_9SACH/4-208             ......qsf---NDFFNKVDT---DDTLQNIRKEYLASKKNLHEL.------..--...-ISASP....TRIt.aKPVVRSTQL..................PT--PPGNINDLERDERLRRQLHDTNQPR.....-------.--......QP.DTGHS-.....----.....-..--..-EQFS.RLES.....LIVEQQRQLDRLRYQLDQYEITNRALRERTYAVEHEL.........RQLRY.TGSL--S..............ID.SYP............................RRETRTAESRVRDNEIGD---LD........FDNTKA--L......LSSS...RI.--EKSQR..RQFSNLDDSTTRILQMTK---npq.......
SPC29_ASHGO/55-290                 .........MNVSSFLNRPDT---DDTLQNIRKEYLNTKRNLHDL.------..--...-LSSSP....TRL...QQGARGAGEmsgn.........applhYVGGQAEPPQQGEQDDRLRQQLRDYMSNKsrsmpPPAKYPA.PG......PG.PADGG-.....----.....-..--..-----.-VQR.....QLDSQKMMIESLKRELDTQRTINSMLFERLDRLEEEV.........---RY.VRHSNRApan........gapFR.SVS............................SAPSSSHTNGHVGS-YASADDTKvl....lgWDQPTL--A......HGGK...HA.QPPQQHT..RTFSNLDDSTARLIQMSAGG-k.........
J7SAJ3_KAZNA/11-172                ......fvr----TFFSRPET---DDTINNFKRDYMESMKKLNMV.LNTSRN..GSp.mRGTTGP....KKV...KEVD----Elnir..........spprIPNERVQSNRKLDDNDNVRLQFK---TRE.....PNSRISStST......LG.PSDEQ-.....---I.....H..VL..IDEMK.ELRE.....TLYRQQTQLQALKVDLKQERQKTSFLQYKVDRLES--.........-----.-------..............--.---............................-----------------------........---------......----...--.-------..---------------------gsrtvpq...
SPC29_KLULA/1-272                  .........MDVSQFLNNVEN---DDTLQNIRKEYLNSKRTLQEL.MTNQSP..TKk.mEFSKKP....TLL...QE--RNSND..................YINRNVNSSKPTD-DEFLRRQLREGLSRK.....PEPKISL.PS......LA.-SDTNR.....LDSI.....Y..SS..VNKID.ELEK.....KLYHHELQIQALKNELYQSNASNRALQNKVAELQDSV.........RMLAA.LSHSNVKadtdnsqlsangkwTR.HYAgpnsngn.............gvyldrpqSAPSTSSTSEWVANALHDSDDTRvl....lgWKQPSSTRV......DNSS...NF.HFPHNQP..RNLSNFDDNTSRLIGVTGKTR..........
J6EDL3_SACK1/1-251                 .........MDYKNFGSNAGKKFQDDTLNRVRKEHQEALKKLREE.------..--...NFSSNT....SELg.kNKQYKAQERmspp.........lhrlsPVNKLEDRKLRSPLDEKLRRQLRESNTRL.....PPPSFSS.YG......IP.SNNRSN.....LERI.....R..RR..TSSPV.RTERfasqdVIDDQRLEIKYLERIVHDQGSIIDNLTSRITRLESFIlnpvsdreeKNFGS.LEHS---..............-N.SFA............................GFPTNKMYGLQMGGLYEK-----........-DMPYGRSS......DNIK...KE.RPRVGRS..SQIHIENESTEDILKILSSS-f.........
A0A0X8HWD7_9SACH/1-247             .........MNMSTFLNRPDT---DDTLQNIRKEYLNTKRNLHEL.------..--...-LTNSP....TRI...SQGTRMSAEaigkgpttqfglqqqqpmPMPKPSPHHAISDQDEKLRHQLRDYISNK.....------D.RH......MA.PVAGSG.....NKPI.....R..GS..ASNNDgGLQR.....QLDSQNFILNSLKRELDMQRTINSMLFERLERLEEEV.........---RY.IRHTGIRqqt.......nvasGR.SVS............................SAPSSSHTNGNGGTSYASGDDTKml....lhWDQMPQ--A......GANK...TI.----KHR..RSLSNLDDSTARLIQMSGQ--fr........
SPC29_YEAST/1-251                  .........MDYSNFGNSASKKFQDDTLNRVRKEHEEALKKLREE.------..--...NFSSNT....SELg.nKKHYRAQERmssp.........lhrlsPTGKSDDRKVKSPLDDKLRRQLREGNTRL.....PPPPFSS.YG......MP.PTNRSN.....LDRI.....R..RR..TSSPV.RTDKfasqnVIDDQRLEIKYLERIVYDQGTVIDNLTSRITRLESFIlnsisdrgdKNFAS.LEHS---..............-R.SFS............................GFPTNKTYGLQMGGLYEN-----........-DMPYRRSS......DNIN...KE.GAREDRS..SQIHIENESTEDILKILSSS-f.........
G8JXL1_ERECY/1-257                 .........MDRSSYLNRPET---DDTLQNIRKEYLNTKRNLHDL.LT-SSP..TR...IPQSTR....GEL...--------Ggkaa..........aglqQQQGAQLAAQDAEQDDRLRQQLRDYMNNRgrhmgAPARYPS.VG......AAaPPAPPL.....LQAAgggsaA..AV..APVEG.SLQR.....QLDNQKLMFDSLKRELDTQRTINNMLFQRLDQLEEDV.........RYLRH.ATNN--Kaqqqqn..nnvggnFR.SVS............................SAPSSSHTTGFGGS-SVSGDDTKvl....lgWDQPSN---......--AV...KQ.--HHPHQ..RSLSNFDDNTAKLIQMSSGA-k.........
A7TKY7_VANPO/6-246                 ...ltkeff-------DRQEV---DDTLQNIRKQYLESKKNLQKLvMMKQSP..ANt.eEF-KVP....SIP...KQ-------..................---KPPKPTRPSDIDEKLRRELRS--SRV.....TTNTVEN.T-......PA.PLGKET.....ITDT.....L..IL..VNEVR.SMKN.....IIQEQRAMIRDLSQDLQVQRSMSYELQSKIHRLEAHI.........RQVELnMRGSKQPyge........ypgND.IFD............................TNRSNYSTTEIENIPKRSAWRTHsl....taPSSSSHSSY......SNSS...NM.NNINNSYsyQSYSTMEDSTTRLIQLSNP--k.........
A0A1G4IZT6_9SACH/5-213             .....gttg-----FFNDPET---DDTLQNIRRDYLASKKNLQEL.------..--...-LVTSP....TTT...RT--RPLQV..................PT-PPMERKTRGN-DELLRQQLREGLRID.....--SRHPS.GS......LP.PAARRD.....LPRK.....VepEH..YTEVD.GLRM.....MVHDQQQSIGRLQRALEAQEARNANLEMRMRTLEHCV.........---AI.LEKS---..............PR.SPY............................E-PRNTEPPGAYESVDHD-----........-NTKVLLNL......DGGQ...PV.------Q..RLHSNYDDSTTNLIKLSQ---issq......
A0A0C7N8A2_9SACH/8-227             ....gffsd---------PET---DDTLRNIRREYLASKKNLQEL.------..--...-LITSP....TSM...RTRQLQNPT..................PVTDFSRKDGRLNNDDHLRLQLREGLKSD.....--PEIMP.AG......AT.PSSYKT.....FQKI.....G..QSkaYNEID.TMRS.....MLYDQQRQINQMQRDFESQGQRNAALHDRVYYLERTV.........AKLEA.ELETQST..............VRdSYE............................PVVRPLRTKIPAPVEFQDHDNTR.......aLLNPQS--M......D---...--.---MAAK..RQISNYEDSTTRLIQMAQD--sn........
C5DXL9_ZYGRC/5-46                  ......tre-----FFDRPEN---DDTLQNIRRQYLESKRNLQDL.MMKQNQ..--...------....---...---------..................-----------------------------.....-------.--......--.------.....----.....-..--..-----.----.....-------------------------------------.........-----.-------..............--.---............................-----------------------........---------......----...--.-------..---------------------ngdad.....
C5DEV0_LACTC/5-214                 .......gl---SAFLSNPET---DDTLQNIRREYLASKKNLQNL.------..--...-LVTSP....TRA...RT--RPLQQip..............tpPINGS---KERAD-DDKLRQQLREGLQPDrf.mnRPPQVPI.PT......AA.RSD---.....----.....-..--..IE---.NLRS.....MLYSQQRVIDELTRGLDAQVIRNSALENRVSMLERYI.........TRLES.QGNSRSP..............EP.QLV............................DEGISRRLRQQYTPLYTD-----........-DENTR-VL......---L...NS.GAVDRPD..RQISNFDDSTTKLLQIARD--ts........
#=GC seq_cons                      ..............FhNpsEs...DDTLQNIR+EYLpSKKNLp-L...............hsssP....oph...pp.....tt...................hst....pppss.D-+LRpQLR-s.ppp.......sth.s.ss......hs.ssstp.........h.....h..t...hsp.t.tlcp.....hl.sQphpIppLpptLcpQpthNptLpp+lptLEcpl.........t.hth.hppo..................c.shs............................sh.pspphst.hss.hts..............sp..t..h.......s.p...p.......tp..RphSNh-DSTs+Llphst...p.........
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