GenomeNet

Database: Pfam
Entry: TRADD_N
LinkDB: TRADD_N
Original site: TRADD_N 
#=GF ID   TRADD_N
#=GF AC   PF09034.11
#=GF DE   TRADD, N-terminal domain
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1f3v
#=GF GA   25.00 25.00;
#=GF TC   36.90 35.70;
#=GF NC   21.30 19.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   10911999
#=GF RT   Solution structure of N-TRADD and characterization of the
#=GF RT   interaction of N-TRADD  and C-TRAF2, a key step in the TNFR1
#=GF RT   signaling pathway.
#=GF RA   Tsao DH, McDonagh T, Telliez JB, Hsu S, Malakian K, Xu GY, Lin
#=GF RA   LL;
#=GF RL   Mol Cell. 2000;5:1051-1057.
#=GF DR   INTERPRO; IPR009095;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   The N terminal domain of 'Tumour necrosis factor receptor type 1
#=GF CC   associated death domain protein' (TRADD) folds into an
#=GF CC   alpha-beta sandwich with a four-stranded beta sheet and six
#=GF CC   alpha helices, each forming one layer of the structure. The
#=GF CC   domain allows docking of TRADD onto 'tumour necrosis factor
#=GF CC   receptor-associated factor' (TRAF): the binding is at the
#=GF CC   beta-sandwich domain, away from the coiled-coil domain. Binding
#=GF CC   ensures the recruitment of cIAPs to the signaling complex, which
#=GF CC   may be important for direct caspase-8 inhibition and the
#=GF CC   immediate suppression of apoptosis at the apical point of the
#=GF CC   cascade [1].
#=GF SQ   163
#=GS A0A3Q2WTM5_HAPBU/90-201   AC A0A3Q2WTM5.1
#=GS A0A226NXD7_COLVI/51-161   AC A0A226NXD7.1
#=GS A0A2Y9K6B6_ENHLU/51-161   AC A0A2Y9K6B6.1
#=GS A0A2Y9DBL6_TRIMA/51-161   AC A0A2Y9DBL6.1
#=GS A0A3Q4BLW0_MOLML/61-172   AC A0A3Q4BLW0.1
#=GS A0A3Q4H635_NEOBR/51-162   AC A0A3Q4H635.1
#=GS A0A2U3YCV2_LEPWE/51-161   AC A0A2U3YCV2.1
#=GS A0A093HMS5_STRCA/49-159   AC A0A093HMS5.1
#=GS D3ZZC5_RAT/51-161         AC D3ZZC5.1
#=GS A0A3P9MX49_POERE/30-141   AC A0A3P9MX49.1
#=GS A0A060W3P9_ONCMY/50-162   AC A0A060W3P9.1
#=GS A0A091EZ17_CORBR/49-159   AC A0A091EZ17.1
#=GS A0A087QX86_APTFO/49-159   AC A0A087QX86.1
#=GS A0A1S3KUZ1_SALSA/58-169   AC A0A1S3KUZ1.1
#=GS A0A091FSA8_9AVES/48-158   AC A0A091FSA8.1
#=GS G3SXW8_LOXAF/51-161       AC G3SXW8.1
#=GS A0A3Q7WJY6_URSAR/51-161   AC A0A3Q7WJY6.1
#=GS I3JED3_ORENI/59-170       AC I3JED3.1
#=GS A0A2K5QF74_CEBCA/51-161   AC A0A2K5QF74.1
#=GS A0A060XHP1_ONCMY/50-161   AC A0A060XHP1.1
#=GS E2REX3_CANLF/51-161       AC E2REX3.1
#=GS H3CV92_TETNG/52-163       AC H3CV92.1
#=GS A0A087X697_POEFO/51-162   AC A0A087X697.1
#=GS K7F8S3_PELSI/48-158       AC K7F8S3.1
#=GS I3MH68_ICTTR/51-161       AC I3MH68.2
#=GS G5C644_HETGA/51-161       AC G5C644.1
#=GS F6YLU1_XENTR/45-155       AC F6YLU1.1
#=GS A0A2I4CTR9_9TELE/51-162   AC A0A2I4CTR9.1
#=GS A0A3Q3A5Q4_KRYMA/51-162   AC A0A3Q3A5Q4.1
#=GS A0A3P8UKA5_CYNSE/51-162   AC A0A3P8UKA5.1
#=GS A0A3P8NPI9_ASTCA/89-200   AC A0A3P8NPI9.1
#=GS A0A3Q7U1L1_VULVU/51-161   AC A0A3Q7U1L1.1
#=GS A0A1L8GKL2_XENLA/45-155   AC A0A1L8GKL2.1
#=GS A0A091CMA9_FUKDA/51-161   AC A0A091CMA9.1
#=GS TRADD_DANRE/59-170        AC Q9I9N5.1
#=GS A0A3P8ZZG2_ESOLU/58-169   AC A0A3P8ZZG2.1
#=GS M4AI71_XIPMA/54-165       AC M4AI71.2
#=GS F6WWG3_MACMU/1-101        AC F6WWG3.2
#=GS A0A2K6AXR7_MACNE/51-161   AC A0A2K6AXR7.1
#=GS A0A452RL63_URSAM/51-161   AC A0A452RL63.1
#=GS A0A3Q0QVS2_AMPCI/51-162   AC A0A3Q0QVS2.1
#=GS G1KXS9_ANOCA/48-159       AC G1KXS9.2
#=GS A0A3B3R9Q2_9TELE/58-169   AC A0A3B3R9Q2.1
#=GS L9K284_TUPCH/51-161       AC L9K284.1
#=GS A0A0Q3MNX8_AMAAE/48-158   AC A0A0Q3MNX8.1
#=GS A0A093PG17_9PASS/49-159   AC A0A093PG17.1
#=GS W5NXI9_SHEEP/53-163       AC W5NXI9.1
#=GS R0KUH6_ANAPL/49-159       AC R0KUH6.1
#=GS A0A218UKM2_9PASE/48-158   AC A0A218UKM2.1
#=GS G1PHB7_MYOLU/50-160       AC G1PHB7.1
#=GS A0A2K5F7V7_AOTNA/51-161   AC A0A2K5F7V7.1
#=GS F7FRX7_MONDO/48-160       AC F7FRX7.1
#=GS A0A1A6FXP7_NEOLE/60-170   AC A0A1A6FXP7.1
#=GS A0A4D9DQZ2_9SAUR/48-158   AC A0A4D9DQZ2.1
#=GS A0A3B3ZEK0_9GOBI/53-164   AC A0A3B3ZEK0.1
#=GS A0A3Q3GLT2_9LABR/52-163   AC A0A3Q3GLT2.1
#=GS S4RMK5_PETMA/1-107        AC S4RMK5.1
#=GS H3B6L3_LATCH/50-160       AC H3B6L3.1
#=GS A0A3B3CXX6_ORYME/51-162   AC A0A3B3CXX6.1
#=GS A0A455AW82_PHYMC/1-101    AC A0A455AW82.1
#=GS F6WBD6_CALJA/51-161       AC F6WBD6.1
#=GS A0A401P4R0_SCYTO/61-168   AC A0A401P4R0.1
#=GS A0A384BFC3_BALAS/79-189   AC A0A384BFC3.1
#=GS A0A3Q7VF72_URSAR/62-172   AC A0A3Q7VF72.1
#=GS A0A3P8T218_AMPPE/51-162   AC A0A3P8T218.1
#=GS A0A1S3PVN2_SALSA/58-169   AC A0A1S3PVN2.1
#=GS D2H9D3_AILME/51-161       AC D2H9D3.1
#=GS TRADD_BOVIN/51-161        AC Q2KI74.1
#=GS A0A2K6L6D8_RHIBE/1-101    AC A0A2K6L6D8.1
#=GS H3C6S5_TETNG/52-163       AC H3C6S5.1
#=GS A0A091HXV1_CALAN/49-159   AC A0A091HXV1.1
#=GS A0A3Q0D0N2_MESAU/51-161   AC A0A3Q0D0N2.1
#=GS G3HZK4_CRIGR/51-161       AC G3HZK4.1
#=GS A0A3Q1AKU6_AMPOC/51-162   AC A0A3Q1AKU6.1
#=GS A0A1U8CVU3_ALLSI/46-156   AC A0A1U8CVU3.1
#=GS A0A2K5YZX5_MANLE/51-161   AC A0A2K5YZX5.1
#=GS A0A3Q2GCF0_CYPVA/51-162   AC A0A3Q2GCF0.1
#=GS TRADD_HUMAN/51-161        AC Q15628.2
#=GS TRADD_HUMAN/51-161        DR PDB; 1F3V A; 51-161;
#=GS TRADD_HUMAN/51-161        DR PDB; 1F2H A; 51-161;
#=GS A0A3B4V6M6_SERDU/51-162   AC A0A3B4V6M6.1
#=GS A0A2U9BDA7_SCOMX/51-162   AC A0A2U9BDA7.1
#=GS A0A3P9C5W7_9CICH/90-201   AC A0A3P9C5W7.1
#=GS A0A0D9QUR7_CHLSB/51-161   AC A0A0D9QUR7.1
#=GS A0A287BPE4_PIG/51-161     AC A0A287BPE4.1
#=GS F1NNN7_CHICK/205-315      AC F1NNN7.5
#=GS G1MQE2_MELGA/49-159       AC G1MQE2.2
#=GS A0A384D0X7_URSMA/62-172   AC A0A384D0X7.1
#=GS A0A3Q1FRW8_9TELE/52-163   AC A0A3Q1FRW8.1
#=GS A0A2K5IUL2_COLAP/51-161   AC A0A2K5IUL2.1
#=GS A0A3B4YL04_SERLL/51-162   AC A0A3B4YL04.1
#=GS A0A226MRC9_CALSU/55-165   AC A0A226MRC9.1
#=GS TRADD_MOUSE/51-161        AC Q3U0V2.1
#=GS A0A3Q1H4I3_ANATE/51-162   AC A0A3Q1H4I3.1
#=GS A0A2K5V3Z0_MACFA/51-161   AC A0A2K5V3Z0.1
#=GS A0A2K6FS15_PROCO/51-161   AC A0A2K6FS15.1
#=GS A0A384BEM2_BALAS/51-161   AC A0A384BEM2.1
#=GS A0A096NJA9_PAPAN/51-161   AC A0A096NJA9.2
#=GS A0A2U3ZRF9_ODORO/62-172   AC A0A2U3ZRF9.1
#=GS H0Z8J2_TAEGU/49-159       AC H0Z8J2.1
#=GS A0A3M0K7R0_HIRRU/103-213  AC A0A3M0K7R0.1
#=GS K7CAG9_PANTR/51-161       AC K7CAG9.1
#=GS A0A1S2ZDP6_ERIEU/57-171   AC A0A1S2ZDP6.1
#=GS A0A2I0M095_COLLI/48-158   AC A0A2I0M095.1
#=GS H0XXX4_OTOGA/51-161       AC H0XXX4.1
#=GS A0A151MLM5_ALLMI/78-188   AC A0A151MLM5.1
#=GS A0A3B4G9M2_9CICH/89-200   AC A0A3B4G9M2.1
#=GS G3PTL1_GASAC/52-163       AC G3PTL1.1
#=GS A0A401S7U9_CHIPU/60-167   AC A0A401S7U9.1
#=GS A0A3Q0E7Y8_TARSY/51-148   AC A0A3Q0E7Y8.1
#=GS A0A3Q1FRU9_9TELE/61-172   AC A0A3Q1FRU9.1
#=GS A0A2R9B614_PANPA/51-160   AC A0A2R9B614.1
#=GS A0A2K6N831_RHIRO/51-161   AC A0A2K6N831.1
#=GS A0A2K5LFL1_CERAT/51-161   AC A0A2K5LFL1.1
#=GS A0A402ENV1_9SAUR/88-185   AC A0A402ENV1.1
#=GS A0A093GHW0_DRYPU/49-159   AC A0A093GHW0.1
#=GS A0A2U4BDG9_TURTR/51-161   AC A0A2U4BDG9.1
#=GS A0A2U3VFH8_ODORO/51-161   AC A0A2U3VFH8.1
#=GS A0A091JF31_EGRGA/49-159   AC A0A091JF31.1
#=GS A0A3Q7TPP4_VULVU/62-172   AC A0A3Q7TPP4.1
#=GS L5KTE4_PTEAL/50-160       AC L5KTE4.1
#=GS A0A1S3EVM7_DIPOR/51-161   AC A0A1S3EVM7.1
#=GS W5MMP9_LEPOC/58-169       AC W5MMP9.1
#=GS W5NXI8_SHEEP/51-161       AC W5NXI8.1
#=GS G1QWB5_NOMLE/51-161       AC G1QWB5.3
#=GS A0A2D0RT15_ICTPU/68-179   AC A0A2D0RT15.1
#=GS A0A384D113_URSMA/51-161   AC A0A384D113.1
#=GS A0A091VGN2_NIPNI/49-159   AC A0A091VGN2.1
#=GS H2VA24_TAKRU/52-163       AC H2VA24.2
#=GS A0A099ZYS7_CHAVO/49-159   AC A0A099ZYS7.1
#=GS A0A493TFH6_ANAPP/174-284  AC A0A493TFH6.1
#=GS A0A3B3I9B7_ORYLA/82-193   AC A0A3B3I9B7.1
#=GS A0A2K6N824_RHIRO/51-161   AC A0A2K6N824.1
#=GS A0A3Q3MTQ0_9TELE/67-178   AC A0A3Q3MTQ0.1
#=GS A0A3B1JLN2_ASTMX/43-154   AC A0A3B1JLN2.1
#=GS M3Y1Z7_MUSPF/51-161       AC M3Y1Z7.1
#=GS G1TNY9_RABIT/51-161       AC G1TNY9.1
#=GS A0A091WKB1_OPIHO/49-159   AC A0A091WKB1.1
#=GS A0A452I4Q7_9SAUR/48-158   AC A0A452I4Q7.1
#=GS A0A3L8SFI9_CHLGU/48-158   AC A0A3L8SFI9.1
#=GS A0A3B3XWS6_9TELE/51-162   AC A0A3B3XWS6.1
#=GS A0A099ZKH8_TINGU/49-159   AC A0A099ZKH8.1
#=GS M7BVK2_CHEMY/48-158       AC M7BVK2.1
#=GS U3JYU2_FICAL/48-158       AC U3JYU2.1
#=GS A0A2Y9FNE3_PHYMC/51-161   AC A0A2Y9FNE3.1
#=GS A0A337S5N8_FELCA/51-161   AC A0A337S5N8.1
#=GS G3R888_GORGO/1-101        AC G3R888.2
#=GS A0A3B3UJU7_9TELE/51-162   AC A0A3B3UJU7.1
#=GS H0VHT2_CAVPO/51-161       AC H0VHT2.1
#=GS A0A1S3W4C3_ERIEU/75-189   AC A0A1S3W4C3.1
#=GS A0A452G086_CAPHI/51-161   AC A0A452G086.1
#=GS A0A2K6UB29_SAIBB/1-101    AC A0A2K6UB29.1
#=GS G3PTL0_GASAC/53-164       AC G3PTL0.1
#=GS A0A0P7XWR9_SCLFO/58-169   AC A0A0P7XWR9.1
#=GS A0A1U7UI92_TARSY/51-161   AC A0A1U7UI92.1
#=GS A0A3B5QSG1_XIPMA/51-162   AC A0A3B5QSG1.1
#=GS A0A3B5AIH2_9TELE/51-162   AC A0A3B5AIH2.1
#=GS A0A384BFT6_BALAS/61-171   AC A0A384BFT6.1
#=GS A0A340X7N1_LIPVE/79-189   AC A0A340X7N1.1
#=GS W5U925_ICTPU/60-171       AC W5U925.1
#=GS F7BI42_HORSE/51-161       AC F7BI42.2
#=GS A0A3B4BTQ3_PYGNA/59-170   AC A0A3B4BTQ3.1
#=GS H2LY60_ORYLA/51-162       AC H2LY60.2
#=GS A0A2Y9P782_DELLE/51-161   AC A0A2Y9P782.1
#=GS A0A1U7QWK2_MESAU/51-161   AC A0A1U7QWK2.1
A0A3Q2WTM5_HAPBU/90-201              ........DSAGGLGTFEILKVHDADPFLGVEVKFVNVAACHQFLESYSSGAVRQYLCQHACRLLALSQ.E...L.TVETQLKAGTHTLDRCLDKLD..LCLQHIHLSQPERLRDEEIDELEQQLQS.....
A0A226NXD7_COLVI/51-161              ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKRENCRRFLQSYREGELQKSLQNHLQLSLAMTT.-...V.PLEMELKAGNEHLDSMLKDED..RCLECIYREKPDRLRDEEIIELEEHLK-g....
A0A2Y9K6B6_ENHLU/51-161              ........ESGGSPDVLQMLKIHLSEPQLIVQVRFRGRQPCSRFLRAYREGSLRAALQECLAAALSLHS.-...V.PLQLELRAGTERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEEALRN.....
A0A2Y9DBL6_TRIMA/51-161              ........ESSGSPDQLQMLKIHRSDPQLILQLRFCGRQPCDRFLRAYREGALRAALQRCLAAALALNS.-...V.LLHLELRAGAERLDALLLDEE..RCLNCIFAQKPDRLRDEELAELEDALRN.....
A0A3Q4BLW0_MOLML/61-172              ........DSAGGLGGYEILKVHDADPLLGVEVKFVDVAACQQFLKSYSSGALHQSLSQHACRLFALPQ.E...L.TVETQLKASTHILDRCLNDLD..LCLQQIHQSQPERLRDEEIDFLEQLLQS.....
A0A3Q4H635_NEOBR/51-162              ........DSAGGLGTFEILKVHDADPFLGVEVKFVNVAACHQFLESYSSGAVRQYLCQHACRLLALSQ.E...L.TVETQLKAGTHTLDRCLDKLD..LCLQHIHLSQPERLRDEEIDELEQQLQS.....
A0A2U3YCV2_LEPWE/51-161              ........ESGGSPDVLQMLKIHRSEPQLIVQLRFCGRQSCSRFLRAYREGSLRAALQGCLGAALALPS.-...V.PLQLELRAGAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A093HMS5_STRCA/49-159              ........DSTGSLNGVDMLKVHCSHPHLIIQLKFCKQENCRRFLQSYREGALQESLQNHLQLSLAMST.-...V.PLEMELKAGSEHLDNMLKDED..RCLECIYKEKPDRLRDEEITELEECLKS.....
D3ZZC5_RAT/51-161                    ........ESGDSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRTALQRCMAAALAQEA.-...V.RLQLELRAGAEQLDSWLTDEE..RCLNYILAQKPDRLRDEELAELEDEFC-k....
A0A3P9MX49_POERE/30-141              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGAVLQSLNQHACRLLGLTQ.D...F.TVRTQLKAGHQNLDLCLDQLA..VCLQHIHLSQPERLRDEEIDHLEQQLQS.....
A0A060W3P9_ONCMY/50-162              ........DSAGGLEGYEILKLHDADPLLGVEVKFVDVAACRRFLQSYGSGAVQQSLSQHTCRLLHIPQqE...L.ALETQLKAGTHTLDFCLDDLE..LCLQHIHQSQPERLRDDEIAELDQQLQS.....
A0A091EZ17_CORBR/49-159              ........DSTGSVNGVDMLKVHCSHPHLIVQLRFCKQENCRRFLRSYREGVLQKSLQSHLQLSLATTT.-...V.PLEVELKAGSEHLDRMLKDED..HCLECIYREKPDRLPDEEITELEECLKS.....
A0A087QX86_APTFO/49-159              ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGALQESLQNHLQLSLAVTT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEECLKS.....
A0A1S3KUZ1_SALSA/58-169              ........DSAGGLEGYEILKLHDADPLLGVEVKFVDVAACRRFLQCYGSGAVQQSLSQHACRLLHGPQ.E...L.VLETQLKAGTHTLDFCLDDLE..LCLQHIHQSQPGRLRDDEIAELDQQLQS.....
A0A091FSA8_9AVES/48-158              ........DSSGSLNGVDMLKVHCSHPHLIVQLKFCKQETCRRFLQSYREGVLQQSLQNHLQLSLAMTA.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYKEKPDRLRDEEITELEECLKS.....
G3SXW8_LOXAF/51-161                  ........ESGGSPDQLQMLKIHRSDPQLILQLRFCGRQPCDRFLRAYREGALRAALQRCLAAALALNS.-...V.RLHLELRAGAERLDTLLPDEE..RCLNCIFAQKPDRLRDEELSELEDALRN.....
A0A3Q7WJY6_URSAR/51-161              ........ESGGSPDVLQILKIHRSEPQLIVQVRFCGRQPCSRFLRAYREGSLRAALQGCLAAALALPS.-...V.PLQLELRASAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
I3JED3_ORENI/59-170                  ........DSAGGLGTFEILKVHDADPFLGVEVKFMNVAACRQFLESYSSGAVRQYLCQHACRLLALPQ.E...L.TVETQLKAGTHILDRCLDKLD..LCLQHINLSQPERLRDEEIDELEQQLQS.....
A0A2K5QF74_CEBCA/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCSRFLRAYREGALRAVLQRSLAAALSQHS.-...L.SLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A060XHP1_ONCMY/50-161              ........DSAGGLEGYEILKLHDADPLLGVEVKFEDVAACRRFLQSYGSGAVQQSLSQHACRLLHGPQ.E...L.ALETQLKAGTHTLDFCLDDLE..LCLQHIHQSQPGRLRDDEIAELDQQLQS.....
E2REX3_CANLF/51-161                  ........ESGGSPDVLQMLKIHRSEPQLIVQLRFCGRQPCSRFLRAYREGSLRAALQACLAAALAQRS.-...M.PLQLELRAGAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALQN.....
H3CV92_TETNG/52-163                  ........DSARGLRGYEILKVHDADPLLGVEVKFVDVAACQQFLSSYGSGALHQSLSQHACRLLALPQ.E...L.RVETQLKASTHVLDLCLDDLQ..CCLKHIHLSQPERLCDEEIDHLEQMLQS.....
A0A087X697_POEFO/51-162              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGAVLQSLNQHACRLLRLPQ.D...F.TVRTQLKAGPQNLDLCLDQLA..VCLQNIHLSQPERLRDEEIDHLEQQLQS.....
K7F8S3_PELSI/48-158                  ........DSTGSLDGVDMLKVHCSEPHLIIQLKFCVRENCRKFLRSYRAGLFRESLQNHLRVTLSVTA.-...V.SVEVELKTGSEQLDHMLNEEE..RCLDYIYKEKPDRLRDEEIAELEESFR-s....
I3MH68_ICTTR/51-161                  ........ESAESPDVLQILKIHRSDPQLIVQLRFCGRQPCSRFLHVYREGTLRAKLQSCLAAALAQHS.-...V.PLQLELRAGAERLDAWLTDEE..HCLNCILAQKPDRLRDEELGELEDALC-n....
G5C644_HETGA/51-161                  ........ESSESPDALQILKIHSSDSQLIVQLRFCGRQSCGCFLRAYREGALRATLQRYLAAALDQPS.-...L.PLQLELLAGAERLDSWLTNEE..RCVHSILAQKPDRLRDEELAELEDALS-n....
F6YLU1_XENTR/45-155                  .......s-TGGCRDSIEILKIHSSDQQLILYLKFCGLEPCQIFLKDYKERKLQMQIQNKLENCFSVAQ.-...L.PIFTELKIDTGEMDSLLEKEE..QCLKYISQMKPTIQKDDEFAEIDERLKS.....
A0A2I4CTR9_9TELE/51-162              ........DSAGGLGGCEILKVHDAEPFLGVEVKFVDVAACQHFLEGYSSGAVRQSLCQHACRLFALPQ.E...F.AVETQLKAGTQILDLCLGDLE..VCLQHIHLSQPERLRDEEIDHLEQQLQS.....
A0A3Q3A5Q4_KRYMA/51-162              ........DSAGGLGGCEILKVHDAEPFLGVEVKFVDVAACQHFLESYSSGAVRQSLCQHACRLFALPQ.E...F.AVETQLKASTQILDLCLDDLE..DCLQHIHLSQPERLRDEEIEHLEQQLQS.....
A0A3P8UKA5_CYNSE/51-162              ........DSAGGLRGYEILKVHDADPFLGVELKFVDVAACQQFLESYSSGAVSQSLSQHACRLLSLSQ.E...L.KVETKLKASTHNLDQDLDELE..LCLERIHLSQPERLRDEEIDHLEQQLR-r....
A0A3P8NPI9_ASTCA/89-200              ........DSAGGLGTFEILKVHDADPFLGVEVKFVNVAACHQFLESYSSGAVRQYLCQHACRLLALSQ.E...L.TVETQLKAGTHTLDRCLDKLD..LCLQHIHLSQPERLRDEEIDELEQQLQS.....
A0A3Q7U1L1_VULVU/51-161              ........ESGGSPDVLQMLKIHRSEPQLIVQLRFCGRQPCSRFLRAYREGSLRAALQACLAAALAQRS.-...M.PLELELRAGAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A1L8GKL2_XENLA/45-155              .......s-TRGCRDSIEILKIHSSDQQLILYLKFCGLEPCQRFLKDYKECKVQMQIQNKLKNCFSVEG.-...L.PIFTELKIDTGEIDSLLEKEE..QCLKYISQMKPTIQKDDELAEIDERLKS.....
A0A091CMA9_FUKDA/51-161              .......e-SSESPDELQILKIHSSDPQLIVQLRFCGRQSCVRFLRAYREGALRVTLQRCLAAALALPS.-...V.QLQLELLTGAERLDAWLTDEE..RCVHSILAQKPDRLRDEELAELEDALN-n....
TRADD_DANRE/59-170                   ........DSVGGLEGYEILKLHDADPYLGVELKFMAMPPCQRFLESYACGSLTQFLSQHASRLLALPD.G...V.EIETQLKAGVHTLDHSLQDIE..ICLDHIRQSQPVRLRDDEVTQLEQQLQN.....
A0A3P8ZZG2_ESOLU/58-169              ........DSSGGLEGYEILKVHDADPLLGVEVKFVDVAACRRFLESYVSGAVLQSLSQHASRLLPGSQ.D...V.AMEIQLKAGMYTLDFCLDDLD..LCLKHIHQSQPGRLRDDEIAELEQQLQS.....
M4AI71_XIPMA/54-165                  ........DSAGGLGGYDILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGAVLQSLNQHACRLLGLPQ.D...F.TVRTQLKAGPQNLDLCLDQLA..VCLQHIHLSQPERLRDEEIDHLEQQLQS.....
F6WWG3_MACMU/1-101                   ........----------MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRTLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A2K6AXR7_MACNE/51-161              ........ESGGSPEVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRTLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A452RL63_URSAM/51-161              ........ESGGSPDVLQILKIHRSEPQLIVQVRFCGRQPCSRFLRAYREGSLRAALQGCLAAALALPS.-...V.PLQLELRASAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A3Q0QVS2_AMPCI/51-162              ........DSAGGLGTYEILKVHDADPFLGVEVKFVDVTACRQFLESYSSGAVRQYLCQHACRLLALPQ.E...L.TVETQLKAGTHILDLCLENLE..LCLQHIHLSQPERLRDEEIDELEQQLQS.....
G1KXS9_ANOCA/48-159                  ........DSTGSFHGVDMLKVYCSDPQLIVQLKFSVKENCRRFLQSYREGVLRDALQRHLQVSLALSS.R...I.PLQTELKAGAEKLDAMIREEE..RCLECIFGEKPNRLRDEEITELEESLKN.....
A0A3B3R9Q2_9TELE/58-169              ........DTAGGLQGYEILKLHDADPLLGIELKFMSKVTCRQFLESYATAAVSQAFTQHTLRILSVSE.D...F.RVETQLKAGENVLDLCLTNQD..LCLSYIHSLQPVRLRDDEVSQLEKQL--ln...
L9K284_TUPCH/51-161                  ......ei--GGSPDVLQMLKMHRSEPQLIVQLRFCGRLLCGRFLRAYREGALRAALQRCLAAALAQRS.-...L.PLQLELRAGSERLDFLLADEE..RCLNCILAQKPDRLRDEELAELEHALR-d....
A0A0Q3MNX8_AMAAE/48-158              ........DSTGSINGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGVLQESLQKHLQLSLAISA.-...V.PLEMELKAGSEHLDSMLKDED..RCLECIYREKPDRLRDEEITKLEECLKS.....
A0A093PG17_9PASS/49-159              ........DSTGSMNGVDMLKVHCSHPQLIVQLKFCRQENCRRFLRSYRDGALQKALQNHLQLSLAMTT.-...V.PLEMELKTGSEHLDNMLKDED..RCLECIYREKPDRLRDEELTELEEHLK-g....
W5NXI9_SHEEP/53-163                  ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRLACSRFLRAYREGALRATLQGCLARALALNS.-...V.PLQLELRAGAEQLDALLTDEE..RCLNCICAQKPDRLRDEELTELEDALRN.....
R0KUH6_ANAPL/49-159                  ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGVLQESLQNHLQLALAMTT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEEYLQS.....
A0A218UKM2_9PASE/48-158              ........DSTGSVNGVDMLKVHCSHPHLIVQLRFCKEENCRRFLQSYREGALQKSLQSHLQLCLATTM.-...V.PLEVELKAGSEHLDKMLKDED..RCLECIYREKPDRLPDEEIMELEESLKS.....
G1PHB7_MYOLU/50-160                  ......ae--SGSPDELQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALEGRLAASLTLHS.-...V.PLQLELRAGAERLDAFLADEE..RCLSSIFAQKPDRLRDEELTELEDALRN.....
A0A2K5F7V7_AOTNA/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCSRFLRAYREGALRAALQRSLAAALSQHS.-...L.SLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
F7FRX7_MONDO/48-160                  .......e-CSGSQDGAQILKIHCSGLQLIVQLKFCGQELCGRFLRSYREGALRDALRNSLVPLLDQAQ.H...LgQLHLELHVGSERLDLMLHEED..RCLRCIHQAKPDRLRDEEISDLEDAFR-s....
A0A1A6FXP7_NEOLE/60-170              ........ESADSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRTALQRCMASALAQEA.-...V.RLQLELRAGAEQLDTWLTDEE..RCLNYILAQKPDRLRDEELAELEKEL--gk...
A0A4D9DQZ2_9SAUR/48-158              ........DSTGSLHGVDMLKVHCSEPHLIIQLKFCMRENCRKFLRSYRAGLFQESLQNHLQVTLSMTA.-...V.PVQVELKAGSEQLDHMLNEEE..RCLECIYKEKPDRLRDEEIAELEESFR-s....
A0A3B3ZEK0_9GOBI/53-164              ........DSAGGLEGYEILKCHDADPFLGVEIKFLDVSTCQQFLESYSSGTMRQSLSQHGCRLLTLPQ.E...I.SVQTQLKASTHTLDPYLDQME..LCLQQIHLSKPERLRDEEIERLEKEL--ld...
A0A3Q3GLT2_9LABR/52-163              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDEAACQYFLESYSSGAVRQSLSQHACRLLALSQ.E...L.TVETQLKASTHILDLYLDKLE..LCLKHIHLSQPERLRDEEIDHLEQQLQS.....
S4RMK5_PETMA/1-107                   agdsdnpp---------VILKVHST--LFGVDLRFDSTASCSAFLERYVNGDMEVQLNRGLAPK----H.Q...D.SFTTSLQVRGLHSDQLISSHDspALLSSLLPPQPTALQDDEVKKMQHDL--lm...
H3B6L3_LATCH/50-160                  ......dv--VGDSPGYEILKILSSDPQLVVQVKFNEVEKCRQFLRIYKSGTLQQLLQERLRAALLLSE.-...L.EVQTELKASSSRLDDYLEKED..HCLSCISEEKPDHQKDEDISRLEECLKN.....
A0A3B3CXX6_ORYME/51-162              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVNMAACKQFLDSYSSRALHQSFSQHAGRLFAVAQ.E...C.TVETQLKASTNILDLCLDKLE..VCLQHIHQSQPERLRDEEIDCLEQQLQ-t....
A0A455AW82_PHYMC/1-101               ........----------MLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...M.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
F6WBD6_CALJA/51-161                  ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCSRFLRAYREGALCAALQRSLAAAVSQHS.-...L.SLQLELRAGAERLDALLADEE..YCLSCILAQQPDRLRDEELAELEDALRN.....
A0A401P4R0_SCYTO/61-168              ........DATGSAGGYEILKIYGSD--FGLQLKFMEEGKCRKFLHSYKNDKLQQALEYHFQNQFIPNT.-...-.AFTTELKAGTVILDNILDNPD..SCLKHIKENEPNHLRDDEVSRLEEDIR-r....
A0A384BFC3_BALAS/79-189              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...M.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
A0A3Q7VF72_URSAR/62-172              ........ESGGSPDVLQILKIHRSEPQLIVQVRFCGRQPCSRFLRAYREGSLRAALQGCLAAALALPS.-...V.PLQLELRASAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A3P8T218_AMPPE/51-162              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSFSQHACRLLVLPQ.E...F.NVETQLKASTHILDLCLDKLD..LCLQHIHLSQPERLRDEEIDHLEQQLQN.....
A0A1S3PVN2_SALSA/58-169              ........DSAGGLEGYEILKLHDADPLLGVEVKFVDVAACRRFLQSYGSGAVQQFLSQHTCRLLHVPQ.E...L.ALETQLKAGTHTLDFCLDDLE..LCLQHIHQSQPERLRDDEIAELDQQLQS.....
D2H9D3_AILME/51-161                  ........ESGGSPDVLQILKIHRSEPQLIVQVRFCGRQPCSRFLRAYREGSLRAALQGCLAAALALPS.-...V.PLQLELRASAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
TRADD_BOVIN/51-161                   ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACSRFLRAYREGALRATLQGCLARALALNS.-...V.PLQLELRAGAEQLDALLTNEE..RCLNCICAQKPDRLRDEELTELENALRN.....
A0A2K6L6D8_RHIBE/1-101               ........----------MLKIHRSDTQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLEDEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
H3C6S5_TETNG/52-163                  ........DSARGLRGYEILKVHDADPLLGVEVKFVDVAACQQFLSSYGSGALHQSLSQHACRLLALPQ.E...L.RVETQLKASTHVLDLCLDDLQ..CCLKHIHLSQPERLCDEEIDHLEQMLQS.....
A0A091HXV1_CALAN/49-159              ........DSTGSVNGVDMLKVHCSHPHLIIQLKFCKQENCRRFLQSYREGRLQESLQNHLQLSLAMTT.-...V.PLEMELKAGKEHLDSMLKDED..HCLECIYREKPDRLRDEEITELEEYFK-s....
A0A3Q0D0N2_MESAU/51-161              ........ESADSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRSALQRCMASALAQEA.-...V.RLQLELRAGAEQLDTWLTDEE..RCLNCILAQKPDRLRDEELAELENELR-k....
G3HZK4_CRIGR/51-161                  ........ESADSPDVLQILKIHCSDQQLIVQLRFCGRLLCGRFLQAYREGALRTALQRCMASALAQEA.-...V.RLQLELRAGAEQLDTWLTDEE..RCLNYILAQKPDRLRDEELAELENELR-k....
A0A3Q1AKU6_AMPOC/51-162              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSFSQHACRLLVLPQ.E...F.NVETQLKASTHILDLCLDKLD..LCLQHIHLSQPERLRDEEIDHLEQQLQN.....
A0A1U8CVU3_ALLSI/46-156              ........DSTGSVNGVDVLKVHCSDPHLIVQLKFCKEENCRKFLQSYREGALQKSLQNHLQLTLSMPT.-...I.SVETDLKTGSEHLDRMLNEVE..RCLDCIYKEKPDRLRDEEIAELEKSLRS.....
A0A2K5YZX5_MANLE/51-161              ........ESGGSPEVLQMLKIHRSDAQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A3Q2GCF0_CYPVA/51-162              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGAVRQSLSQHACRLLAVPQ.D...F.TVETQLKAGTQNLDLCLDQLT..VCLQHIHLSQPGRLRDEEIERLEQQLQN.....
TRADD_HUMAN/51-161                   ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHS.-...V.PLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
#=GR TRADD_HUMAN/51-161        SS    ........HHT--TTTEEEEEEEEETTCEEEEEEEESHHHHHHHHHHHHCCHHHHHHHHHHHHHCT-S-.-...-.-EEEEEECTTEEHHHHCC-HH..HHHHHHHHS---BSS-HHHHHHHHHHHH.....
A0A3B4V6M6_SERDU/51-162              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSLSQHACRLLALPQ.E...L.TVETQLKASTHILDLYLDKLE..LCLQHIHLSQPERLRDEEIDRLEEQLQS.....
A0A2U9BDA7_SCOMX/51-162              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSLSQHACRLLALPQ.E...L.TVETQLKASTHILDLNLDKLE..LCLEHIHHSQPERLRDEEIDHLEQQLQS.....
A0A3P9C5W7_9CICH/90-201              ........DSAGGLGTFEILKVHDADPFLGVEVKFVNVAACHQFLESYSSGAVRQYLCQHACRLLALSQ.E...L.TVETQLKAGTHTLDRCLDKLD..LCLQHIHLSQPERLRDEEIDELEQQLQS.....
A0A0D9QUR7_CHLSB/51-161              ........ESGGSPEVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A287BPE4_PIG/51-161                ........ESGGSPEELQMLKIHRSDPQLIVQLRFCGRQACSRFLRAYREGALRTALQACLEAALALSS.-...V.PLQLELRASAERLDALLTDEE..RCLNFIFAQKPDRLRDEELTELEDALRN.....
F1NNN7_CHICK/205-315                 ........DSTGSMNGVDVLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGELQKSLQNHLQLSLAMTT.-...V.PLEMELKAGNEHLDSMLKDED..RCLECIYREKPDRLRDEEITELEERLKS.....
G1MQE2_MELGA/49-159                  ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGLLQKSLQNHLQLSLAMTT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEERLKS.....
A0A384D0X7_URSMA/62-172              ........ESGGSPDVLQILKIHRSEPQLIVQVRCCGRQPCSRFLRAYREGSLRAALQGCLAAALALPS.-...V.PLQLELRASAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A3Q1FRW8_9TELE/52-163              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSFSQHACRLLVLPQ.E...F.SVETQLKASTHILDLCLDKLD..LCLQHIHLSQPERLRDEEIDHLEQQLQN.....
A0A2K5IUL2_COLAP/51-161              ........ESGGSPEVLQMLKIHCSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLATALAQRS.-...V.ALQLELRAGAERLDALLEDEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A3B4YL04_SERLL/51-162              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVTACQQFLESYSSGAVRQSVSQHACRLLALPQ.E...L.TVETQLKASTHILDLYLDKLE..LCLQHIHLSQPERLRDEEIDRLEEQLQS.....
A0A226MRC9_CALSU/55-165              ........DSTGSVNGVDMLKVHCSYPHLIVQLKFCKRENCRRFLQSYREGELQKSLQNHLQLSLAMTT.-...V.PLEMELKAGNEHLDSMLKDED..RCLECIYREKPDRLRDEEIIELEEHLK-g....
TRADD_MOUSE/51-161                   ........ESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQEA.-...L.RLQLELRAGAEQLDSWLTDEE..RCLNYILAQKPDRLRDEELAELEDELC-k....
A0A3Q1H4I3_ANATE/51-162              ........DSAGGVGGYEILKVHDADPFLGVEVKFMDVAACRQFLESYSSGTLRQFLSQHACRLLALPQ.E...P.PVETQLKAGTHILDLCLDKLD..VCLRHVHLSQPERLRDEEIESLEQQLQ-r....
A0A2K5V3Z0_MACFA/51-161              ........ESGGSPEVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRTLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A2K6FS15_PROCO/51-161              ........ESGGSPDVLQILKIHRSDPQLIVQLRFCGRQPCSRFLRAYREGALRAALQRGLAAALAQHP.-...V.PLQLELRAGAEQLDAVLTDEE..RCLSYILAQKPDRLRDEELAELEDAFR-n....
A0A384BEM2_BALAS/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...M.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
A0A096NJA9_PAPAN/51-161              ........ESGGSPEVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A2U3ZRF9_ODORO/62-172              ........ESGGSPDVLQMLKIHRSEPQLIVQLRFCGRQPCSRFLRAYREGSLRAALQGCLGAALALHS.-...V.PLQLELRAGAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
H0Z8J2_TAEGU/49-159                  ........DSTGSVNGVDMLKVHCSHPHLIVQLRFCKEENCRRFLQSYREGALQKSLQSHLQLCLATTM.-...V.PLELELKAGSEHLDKMLKDED..RCLECIFREKPDRLPDEEIMELEERLKS.....
A0A3M0K7R0_HIRRU/103-213             ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLRSYREGALQKSLQSHLQLSLATTT.-...V.PLKVELKAGSEHLDKMLKDED..HCLECIYREKPDRLPDEEITELEKGLKS.....
K7CAG9_PANTR/51-161                  ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHS.-...V.PLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A1S2ZDP6_ERIEU/57-171              ......en--GGSPDTLQILKIHRSDPQLIVQVRFSGRQPCCCFLSAYREGALRSALQKSLAAALTTHL.HsvpL.QLQLELRAGEERLDTLLTDEE..RCLTCIFAQKPDRLRDEELIELEAALQN.....
A0A2I0M095_COLLI/48-158              ........DSTGSMNGAEILKVHCSHPHLIVQLKFLKQENCRRFLRSYREGALQESLQNHLQLSLATTT.-...V.SLETELKAGNEHLDKMLKDED..RCLECIYREKPDRLRDEEITELEECLKS.....
H0XXX4_OTOGA/51-161                  ........ESGGSPEVLQILKIHRSDPQLIVQLRFCGSQSCGRFLRDYREGALRAALQRGLAAALAHHT.-...V.PLQLELRAGAERLDAVLTDEE..RCLNSILAQKPDRLRDEELAELEDALRN.....
A0A151MLM5_ALLMI/78-188              ........DSTGSVNGVDVLKVHCSDPHLIVQLKFCKEENCRKFLQSYREGALQKSLQNHLQLTLSMPT.-...I.SVETDLKTGSEHLDRMLNEVE..RCLDCIYKEKPDRLRDEEIAELEKSLRS.....
A0A3B4G9M2_9CICH/89-200              ........DSAGGLGTFEILKVHDADPSLGVEVKFVNVAACHQFLESYSSGAVRQYLCQHACRLLALSQ.E...L.TVETQLKAGTHTLDQCLDKLD..LCLQHIHLSQPERLRDEEIDELEQQLQS.....
G3PTL1_GASAC/52-163                  ........DSAGGLGGHEILKIHDADPFLGVEVKFNDMLACRQFLESYSSGAVRQSLSQHAGRLLTLPQ.E...F.TVETQLKASAHILDLCLDQLE..LCLQHVHLSQPERLRDEEIEHLEKQLE-i....
A0A401S7U9_CHIPU/60-167              ........DAAGSSGGVEILKIYGSG--FGLELKFTEERKCKNFLHNYRNDKLQQALVYHFRNQ-SIPN.-...F.TCSTELKAGTVTLDDILENPE..DCLRHIKENEPNHLRDDEVSRLEEDIR-r....
A0A3Q0E7Y8_TARSY/51-148              ........ESGGSRDVLQMLKIHRSDPQLIVQVRFCGRQPCGRFLRAYREGALRAALQRSLAAALARDA.-...V.PLQLELRAGGERLDALLTDEE..RCLSCILAQK------------------vrpgw
A0A3Q1FRU9_9TELE/61-172              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSFSQHACRLLVLPQ.E...F.SVETQLKASTHILDLCLDKLD..LCLQHIHLSQPERLRDEEIDHLEQQLQN.....
A0A2R9B614_PANPA/51-160              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYR-GALRAALQRSLAAALAQHS.-...V.PLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A2K6N831_RHIRO/51-161              ........ESGGSPEVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLEDEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A2K5LFL1_CERAT/51-161              ........ESGGSPEVLQMLKIHRSDAQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A402ENV1_9SAUR/88-185              ........DSTGSFNGVDMLKVHCSDPDLIVQLKFCNQVNCLKFLQSYREGTLHTSLQRHLKVSLATPT.P...V.SVQMELKTGAGKLDSMLLEEE..RCVECISQEK------------------vtae.
A0A093GHW0_DRYPU/49-159              ........DSTGSMSGVDMLKVHCSHPHLIVQLKFCKRESCRRFLRSYREGSLQKSLQSHLQLSLATST.-...V.PLETELKAGSEHLDSMLKDED..HCLECIHREKPDRLRDEEISELEESLKS.....
A0A2U4BDG9_TURTR/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...V.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
A0A2U3VFH8_ODORO/51-161              ........ESGGSPDVLQMLKIHRSEPQLIVQLRFCGRQPCSRFLRAYREGSLRAALQGCLGAALALHS.-...V.PLQLELRAGAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A091JF31_EGRGA/49-159              ........DSTGSMNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLRSYREGVLQESLKNHLQLFLAITT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEECLKS.....
A0A3Q7TPP4_VULVU/62-172              ........ESGGSPDVLQMLKIHRSEPQLIVQLRFCGRQPCSRFLRAYREGSLRAALQACLAAALAQRS.-...M.PLELELRAGAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
L5KTE4_PTEAL/50-160                  ......ae--SGSPDVLQMLKIHRSDRQLILQLRFCGRQPCSRFIHAYREGALRTSLEVGLAAALALRS.-...V.QLQLELRAGAELLDDLLMDEE..RCLSCIFAHKPDRLRDEELAELEAALRN.....
A0A1S3EVM7_DIPOR/51-161              ........ESSESPDVLQILKIHRGDPQLIVQLRFCGRQCCARFLRAYREGALRAALRQCLAQALSRPS.-...L.QLQLELRAGTELLDASLTDEE..RCLNCILAQKPDRLRDEELTELEDALRN.....
W5MMP9_LEPOC/58-169                  ........DAAGGLEGYEILKLHDAQPSLGIQIKFMDEGVCRKFLQSYASGLVQQFFGQHLSRTLSGLK.E...P.TFETQLKAGSETLDNCLPDVD..LCLHHVNRAQPDRLQDEEVSELEQQLQS.....
W5NXI8_SHEEP/51-161                  ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRLACSRFLRAYREGALRATLQGCLARALALNS.-...V.PLQLELRAGAEQLDALLTDEE..RCLNCICAQKPDRLRDEELTELEDALRN.....
G1QWB5_NOMLE/51-161                  ........ESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.PLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A2D0RT15_ICTPU/68-179              .......d-VAGGLDGYEILKLHDADPFLGVELKFMDISPCRRFLDSYSCGSLLQFLSQHASRLLSIPD.G...V.SVEAMLKAGTYTLDHSLQDQE..RCLQLIYQSQPVRLRDDEVTQLEQQLQN.....
A0A384D113_URSMA/51-161              ........ESGGSPDVLQILKIHRSEPQLIVQVRCCGRQPCSRFLRAYREGSLRAALQGCLAAALALPS.-...V.PLQLELRASAERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEDALRN.....
A0A091VGN2_NIPNI/49-159              .......d-CTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGVLQESLQNHLQLSLAVAT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEECLKS.....
H2VA24_TAKRU/52-163                  ........DSARGLSGYEILKVHDADPFLGVEVKFMDVAACQQFLNSYSSGALHQSLSQHACRLLALPQ.E...L.TVETQLKASTHILDLCLDDLE..RCLKHIHLSQPERLCDEEIDHLEQELRS.....
A0A099ZYS7_CHAVO/49-159              ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGALQESLQNHLQLSLAMTT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEECLKS.....
A0A493TFH6_ANAPP/174-284             ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGVLQESLQNHLQLALAMTT.-...V.PLEMELKAGNEHLDNMLKDED..RCLECIYREKPDRLRDEEITELEEYLQS.....
A0A3B3I9B7_ORYLA/82-193              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVNMAACKQFLDSYSSGALHQSFSQHAGRLFAVAQ.E...C.SVETQLKASTNILDHCLDKLE..VCLQHIHQSQPERLRDEEIDQLEQQLQ-t....
A0A2K6N824_RHIRO/51-161              ........ESGGSPEVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQRS.-...V.ALQLELRAGAERLDALLEDEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A3Q3MTQ0_9TELE/67-178              ........DSVGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSLSQHACRLLALSQ.E...F.TVETQLKASTHTLDCCLDKLE..LCLQHIHLSQPERLRDEEIDSLEQQLQN.....
A0A3B1JLN2_ASTMX/43-154              .......d-VAGGLDGYEILKLHDADPFLGVELKFVDPLPCKRFLDSYACGALLQCVSQHASRLLALPD.T...L.PVHAMLKAGTHTLDQNLQDPE..LCLQYIYQSQPVRLRDDEVTQLEQQLQN.....
M3Y1Z7_MUSPF/51-161                  ........ESGGSPDVLQMLKIHRSEPQLIVQVRFRGRQPCSRFLRAYREGSLRATLQECLAGALALHS.-...V.PLQLELRAGTERLDTLLTDEE..RCLSCIFAQKPDRLRDEELSELEEALRN.....
G1TNY9_RABIT/51-161                  ........ESGGSPDVVQMLKIHRSDPQLVVQLRFCGRQRCGRFLHAYREGALRVALQKRLAAALQRHS.-...L.PLRLELRAGSELLDAWLTDEE..RCLSCILAQKPDRLRDEELAELEDALRN.....
A0A091WKB1_OPIHO/49-159              ........DSTGSVNGVDMLKVHCSHPHLIVQLKFCKQENCRRFLQSYREGALQESLQNHLQLSLALST.-...V.PLEMELKAGNEHLDSMLKDED..RCLECIYREKPDRLRDEEITELEECLKS.....
A0A452I4Q7_9SAUR/48-158              ........DSTGSLHGVDMLKVHCSEPHLIIQLKFCLRENCRKFLQSYRAGLFRESLQNHLQVTLSMTA.-...V.PVQVELKAGSEQLDRMLNEEE..RCLDCIYKEKPDRLRDEEIAELEESFR-s....
A0A3L8SFI9_CHLGU/48-158              ........DSTGSVNGVDMLKVHCSHPHLIVQLRFCKEENCRRFLQSYREGALQTSLQSHLQLCLATTM.-...V.PLEVELKAGSEHLDKMLKDED..RCLECIYREKPDRLPDEEIMELEECLKS.....
A0A3B3XWS6_9TELE/51-162              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGAVLQSLNQHACRLLRLPQ.D...F.TVRTQLKAGPQNLDLCLDQLA..VCLQNIHLSQPERLRDEEIDHLEQQLQS.....
A0A099ZKH8_TINGU/49-159              ........DSTGSLNGVDMLKVHCSHPHLIIQLKFCKQENCRRFLRSYREGALQESLQNHLQLSLAMSK.-...V.PLEMELKAGSEHLDNMLKDED..RCLECIYKEKPDRLRDEEITELEECLKS.....
M7BVK2_CHEMY/48-158                  ........DSTGGLHGVDMLKVHCSEPHLIIQLKFCMRENCRKFLRSYRAGLFRESLQKHLQVTLSMTA.-...V.PVQVELKAGSEQLDHMLNEEE..RCLECIYNEKPDRLRDEEIAELEESFR-s....
U3JYU2_FICAL/48-158                  .......d-CTGSVNGVDMLKVHCSHPHLIVQLKFCKRENCRRFLRSYREGALQKSLQSHLQLSLAITT.-...V.PLEVELKAGSEHLDKMLKDED..RCLECIYREKPDRLPDEEITELEECLKS.....
A0A2Y9FNE3_PHYMC/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...M.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
A0A337S5N8_FELCA/51-161              ........ESVGSPEMLQMLKIHRSEPQLIVQVRFCGRQPCSRFLRAYREGALRAALQGCLAAALAQHS.-...V.PLELELRAGVERLDTLLTDEE..RCLSCIFAQKPDRLRDDELSELEDALRN.....
G3R888_GORGO/1-101                   ........----------MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHS.-...V.PLQLELRAGAERLDALLADEE..RCLSCILAQQPDRLRDEELAELEDALRN.....
A0A3B3UJU7_9TELE/51-162              ........DSAGGLGGYEILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGTVLQSLNQHACRLLGLPE.D...F.TVRTQLKAGPQNLDLCLDQLP..VCLQHIHLSQPERLRDEEIDHLEQQLQS.....
H0VHT2_CAVPO/51-161                  ........ESSQGPDVLQILKIHRSDPQLIMQLRFCGRQSCDRFLRAYREGALRATLQRCLAAALAQPS.-...M.LLQLELRAGAEQLDAWLTDEE..HCVQTILAQKPDRLRDEELTELEDALS-s....
A0A1S3W4C3_ERIEU/75-189              ......en--GGSPDTLQILKIHRSDPQLIVQVRFSGRQPCCCFLSAYREGALRSALQKSLAAALTTHL.HsvpL.QLQLELRAGEERLDTLLTDEE..RCLTCIFAQKPDRLRDEELIELEAALQN.....
A0A452G086_CAPHI/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRLACSRFLRAYREGALRATLQGCLARALALNS.-...V.PLQLELRAGAEQLDALLTDEE..RCLNCICAQKPDRLRDEELTELEDALRN.....
A0A2K6UB29_SAIBB/1-101               ........----------MLKIHRSDPQLVVQLRFCGRQPCSCFLRAYREGALRAALQRSLAAALFQHS.-...L.SLQLELRAGAERLDALLADEE..RCLNCILAQQPDRLRDEELAELEDALRN.....
G3PTL0_GASAC/53-164                  ........DSAGGLGGHEILKIHDADPFLGVEVKFNDMLACRQFLESYSSGAVRQSLSQHAGRLLTLPQ.E...F.TVETQLKASAHILDLCLDQLE..LCLQHVHLSQPERLRDEEIEHLEKQLE-i....
A0A0P7XWR9_SCLFO/58-169              ........DTAGGLQGYEILKLHDADPYLGVEIKFVDCDVCRRFLESYAAGAVSQFFTQHALRVLSGSE.D...F.TVDTQLKAGTEVLDQCLTNQE..LCLDHIHSLQPVRLRDDEVTQLERQLQN.....
A0A1U7UI92_TARSY/51-161              ........ESGGSRDVLQMLKIHRSDPQLIVQVRFCGRQPCGRFLRAYREGALRAALQRSLAAALARDA.-...V.PLQLELRAGGERLDALLTDEE..RCLSCILAQKPDRLRDEELAELENALRN.....
A0A3B5QSG1_XIPMA/51-162              ........DSAGGLGGYDILKVHDAEPFLGVEVKFVDVAACQQFLESYSSGAVLQSLNQHACRLLGLPQ.D...F.TVRTQLKAGPQNLDLCLDQLA..VCLQHIHLSQPERLRDEEIDHLEQQLQS.....
A0A3B5AIH2_9TELE/51-162              ........DSAGGLGGYEILKVHDADPFLGVEVKFVDVAACQQFLESYSSGAVRQSFSQHACRLLALPQ.E...F.SVETQLKASTHILDLCLDKLD..LCLQHINLSQPERLRDEEIDHLELELQN.....
A0A384BFT6_BALAS/61-171              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...M.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
A0A340X7N1_LIPVE/79-189              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...V.PLRLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
W5U925_ICTPU/60-171                  .......d-VAGGLDGYEILKLHDADPFLGVELKFMDISPCRRFLDSYSCGSLLQFLSQHASRLLSIPD.G...V.SVEAMLKAGTYTLDHSLQDQE..RCLQLIYQSQPVRLRDDEVTQLEQQLQN.....
F7BI42_HORSE/51-161                  ........ESSGSPDVLQMLKIHRSDPQLIVQLRFCGRQACGRFLRAYREGALRAALQGCLEAALTLQS.-...L.SLELELRAGAERLDTLLTDEE..RCLNCIFAQKPDRLRDEELVELENVLR-n....
A0A3B4BTQ3_PYGNA/59-170              .......d-VAGGLDGYEILKLHDADPFLGVELKFMDALPCKRFLDSYACGSLLQFLSQHASRLLTLPD.E...V.AMEAVLKAGTHILDHDLKNTE..LCLQHIHQSQPVRLRDDEVTQLEQQLQN.....
H2LY60_ORYLA/51-162                  ........DSAGGLGGYEILKVHDAEPFLGVEVKFVNMAACKQFLDSYSSGALHQSFSQHAGRLFAVAQ.E...C.SVETQLKASTNILDHCLDKLE..VCLQHIHQSQPERLRDEEIDQLEQQLQ-t....
A0A2Y9P782_DELLE/51-161              ........ESGGSPDVLQMLKIHRSDPQLIVQLRFSGRQACGRFLRTYREGALRAALQGCLAAELTLHS.-...V.PLQLELRAGAEQLDALLTDEE..RCLNCIFAQKPDRLRDEELTELEDALRN.....
A0A1U7QWK2_MESAU/51-161              ........ESADSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRSALQRCMASALAQEA.-...V.RLQLELRAGAEQLDTWLTDEE..RCLNCILAQKPDRLRDEELAELENELR-k....
#=GC SS_cons                         ........HHT--TTTEEEEEEEEETTCEEEEEEEESHHHHHHHHHHHHCCHHHHHHHHHHHHHCT-S-.-...-.-EEEEEECTTEEHHHHCC-HH..HHHHHHHHS---BSS-HHHHHHHHHHHH.....
#=GC seq_cons                        ........-SuGS.sslphLKlHcSDPpLIVQL+FssppsCpRFLcuYREGALRpuLQppLstsLAhss.....l.sLphEL+AGsEpLDshLsDEE..RCLpsIatppPDRLRDEElsELEctL+s.....
//
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