GenomeNet

Database: Pfam
Entry: TRAF6_Z2
LinkDB: TRAF6_Z2
Original site: TRAF6_Z2 
#=GF ID   TRAF6_Z2
#=GF AC   PF18048.2
#=GF DE   TNF receptor-associated factor 6 zinc finger 2
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF02238
#=GF GA   27.40 27.40;
#=GF TC   27.40 37.80;
#=GF NC   26.60 26.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   19465916
#=GF RT   E2 interaction and dimerization in the crystal structure of
#=GF RT   TRAF6.
#=GF RA   Yin Q, Lin SC, Lamothe B, Lu M, Lo YC, Hura G, Zheng L, Rich RL,
#=GF RA   Campos AD, Myszka DG, Lenardo MJ, Darnay BG, Wu H;
#=GF RL   Nat Struct Mol Biol. 2009;16:658-666.
#=GF DR   INTERPRO; IPR041310;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is the second of three zinc fingers of Homo sapiens
#=GF CC   TNF receptor associated factor 6 (TRAF6). TRAF6 mediates Lys63
#=GF CC   (K63)-linked polyubiquitination for Necrosis Factor-kappaB
#=GF CC   activation. The first three residues and the last Cys of finger
#=GF CC   1 form a classical type I beta-turn [1].
#=GF SQ   83
#=GS A0A2I3G7Q8_NOMLE/157-183  AC A0A2I3G7Q8.1
#=GS A0A2U3XYU7_LEPWE/157-183  AC A0A2U3XYU7.1
#=GS A0A2K5XGP2_MANLE/157-183  AC A0A2K5XGP2.1
#=GS U3KNH2_RABIT/157-183      AC U3KNH2.1
#=GS A0A2K6K6R3_RHIBE/157-183  AC A0A2K6K6R3.1
#=GS A0A2K5PCQ6_CEBCA/157-183  AC A0A2K5PCQ6.1
#=GS A0A1S3FGD6_DIPOR/157-183  AC A0A1S3FGD6.1
#=GS A0A1S2ZN24_ERIEU/157-183  AC A0A1S2ZN24.1
#=GS G1S8G6_NOMLE/157-183      AC G1S8G6.1
#=GS A0A2Y9RIB6_TRIMA/157-183  AC A0A2Y9RIB6.1
#=GS A0A2I2YLX3_GORGO/157-183  AC A0A2I2YLX3.1
#=GS A0A340Y0S0_LIPVE/158-184  AC A0A340Y0S0.1
#=GS A0A096MX12_PAPAN/157-183  AC A0A096MX12.1
#=GS A0A2K6RDB7_RHIRO/157-183  AC A0A2K6RDB7.1
#=GS F6URD5_HORSE/180-206      AC F6URD5.2
#=GS A0A2I3RKM7_PANTR/157-183  AC A0A2I3RKM7.1
#=GS TRAF6_MACMU/157-183       AC B6CJY5.1
#=GS A0A2U4CF05_TURTR/158-184  AC A0A2U4CF05.1
#=GS A0A1U7TT03_TARSY/157-183  AC A0A1U7TT03.1
#=GS G1P0K0_MYOLU/157-183      AC G1P0K0.1
#=GS TRAF6_BOVIN/158-184       AC Q3ZCC3.1
#=GS A0A452SD59_URSAM/157-183  AC A0A452SD59.1
#=GS A0A2K5ULJ8_MACFA/157-183  AC A0A2K5ULJ8.1
#=GS A0A2K6NJ05_RHIRO/157-183  AC A0A2K6NJ05.1
#=GS A0A2K6BKS9_MACNE/157-183  AC A0A2K6BKS9.1
#=GS TRAF6_RAT/157-183         AC B5DF45.1
#=GS A0A2U3WKM7_ODORO/157-183  AC A0A2U3WKM7.1
#=GS A0A2Y9JQV9_ENHLU/157-183  AC A0A2Y9JQV9.1
#=GS A0A091CRB5_FUKDA/185-211  AC A0A091CRB5.1
#=GS A0A1S3FGQ5_DIPOR/180-206  AC A0A1S3FGQ5.1
#=GS E2RDE8_CANLF/157-183      AC E2RDE8.2
#=GS A0A384A199_BALAS/158-184  AC A0A384A199.1
#=GS TRAF6_HUMAN/157-183       AC Q9Y4K3.1
#=GS TRAF6_HUMAN/157-183       DR PDB; 3HCS B; 157-183;
#=GS TRAF6_HUMAN/157-183       DR PDB; 3HCU A; 157-159;
#=GS TRAF6_HUMAN/157-183       DR PDB; 3HCS A; 157-183;
#=GS A0A2Y9PAB2_DELLE/177-203  AC A0A2Y9PAB2.1
#=GS A0A2Y9ERK4_PHYMC/177-203  AC A0A2Y9ERK4.1
#=GS A0A3Q7W437_URSAR/157-183  AC A0A3Q7W437.1
#=GS A0A2K6EGK7_PROCO/157-183  AC A0A2K6EGK7.1
#=GS F7HMD7_MACMU/157-183      AC F7HMD7.2
#=GS A0A2I3T972_PANTR/157-183  AC A0A2I3T972.1
#=GS A0A2R9CI00_PANPA/157-183  AC A0A2R9CI00.1
#=GS G5B132_HETGA/159-185      AC G5B132.1
#=GS A0A2K5IN10_COLAP/157-183  AC A0A2K5IN10.1
#=GS H0V3B1_CAVPO/159-185      AC H0V3B1.1
#=GS W5QCP4_SHEEP/158-184      AC W5QCP4.1
#=GS H2NDP0_PONAB/239-265      AC H2NDP0.2
#=GS H0WWF3_OTOGA/157-183      AC H0WWF3.1
#=GS G1T2F3_RABIT/157-183      AC G1T2F3.1
#=GS A0A384BRZ7_URSMA/157-183  AC A0A384BRZ7.1
#=GS H2Q3F3_PANTR/157-183      AC H2Q3F3.1
#=GS A0A452ESI6_CAPHI/189-215  AC A0A452ESI6.1
#=GS A0A2K6EGL2_PROCO/157-183  AC A0A2K6EGL2.1
#=GS A0A2I2U6B5_FELCA/157-183  AC A0A2I2U6B5.1
#=GS A0A2K5DHG0_AOTNA/157-183  AC A0A2K5DHG0.1
#=GS F6W175_MACMU/157-183      AC F6W175.2
#=GS A0A3Q2HK71_HORSE/157-183  AC A0A3Q2HK71.1
#=GS A0A3Q7U5G5_VULVU/157-183  AC A0A3Q7U5G5.1
#=GS A0A2K5WZD0_MACFA/157-183  AC A0A2K5WZD0.1
#=GS A0A2R8ZJW9_PANPA/157-183  AC A0A2R8ZJW9.1
#=GS TRAF6_MOUSE/157-183       AC P70196.2
#=GS A0A452ESH1_CAPHI/158-184  AC A0A452ESH1.1
#=GS A0A384A1C9_BALAS/177-203  AC A0A384A1C9.1
#=GS A0A2K6TWI5_SAIBB/171-197  AC A0A2K6TWI5.1
#=GS A0A286XCF0_CAVPO/159-185  AC A0A286XCF0.1
#=GS G3QST5_GORGO/157-183      AC G3QST5.2
#=GS A0A337SQ77_FELCA/157-183  AC A0A337SQ77.1
#=GS I3M9G1_ICTTR/157-183      AC I3M9G1.1
#=GS A0A2U4CF07_TURTR/177-203  AC A0A2U4CF07.1
#=GS A0A452ETM2_CAPHI/158-184  AC A0A452ETM2.1
#=GS F7ES31_CALJA/157-183      AC F7ES31.1
#=GS A0A2Y9ERN8_PHYMC/158-184  AC A0A2Y9ERN8.1
#=GS A0A1A6HQX7_NEOLE/157-183  AC A0A1A6HQX7.1
#=GS A0A2K6MKD5_RHIBE/157-183  AC A0A2K6MKD5.1
#=GS G3GZ05_CRIGR/135-161      AC G3GZ05.1
#=GS G3TH24_LOXAF/157-183      AC G3TH24.1
#=GS TRAF6_CERAT/157-183       AC B6CJY4.1
#=GS TRAF6_PIG/158-184         AC A7XUJ6.1
#=GS A0A1U8C5B2_MESAU/157-183  AC A0A1U8C5B2.1
#=GS M3YK34_MUSPF/157-183      AC M3YK34.1
#=GS A0A2K6DR01_MACNE/157-183  AC A0A2K6DR01.1
#=GS A0A0D9QZK2_CHLSB/173-199  AC A0A0D9QZK2.1
#=GS A0A2Y9NZA9_DELLE/158-184  AC A0A2Y9NZA9.1
#=GS G1M5H7_AILME/157-183      AC G1M5H7.1
#=GS G3TWA4_LOXAF/157-183      AC G3TWA4.1
A0A2I3G7Q8_NOMLE/157-183             FALMDCPQCQCPFQKFHINIHILKDCP
A0A2U3XYU7_LEPWE/157-183             FALMNCPQCQRPFQKCQLNIHILKECP
A0A2K5XGP2_MANLE/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
U3KNH2_RABIT/157-183                 FALVNCPQCQRPFQKCQINTHILKDCP
A0A2K6K6R3_RHIBE/157-183             FALMDCPQCQRPFQKFHINIHILKDCP
A0A2K5PCQ6_CEBCA/157-183             FALMDCPQCQHPFQKCQINIHILKDCP
A0A1S3FGD6_DIPOR/157-183             FALMNCPQCQHPLPKFQFNIHVLEDCP
A0A1S2ZN24_ERIEU/157-183             FALINCPQCQRPFPKYQSKIHIHKECP
G1S8G6_NOMLE/157-183                 FALMDCPQCHRPFQKFHINIHILKDCP
A0A2Y9RIB6_TRIMA/157-183             FALMDCPQCQRPFQKCHLNIHILTECP
A0A2I2YLX3_GORGO/157-183             FALMDCPQCQPPFQKFHINIHILKGCP
A0A340Y0S0_LIPVE/158-184             FALMNCPQCHRPFQKCQLNIHIVKECP
A0A096MX12_PAPAN/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
A0A2K6RDB7_RHIRO/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
F6URD5_HORSE/180-206                 FALMNCPQCQHPFQKCQLNIHMLKECP
A0A2I3RKM7_PANTR/157-183             FALMDCPQCQPPFQKFHINIHIMKGCP
TRAF6_MACMU/157-183                  FALVDCPQCQRPFQKFHINIHILKDCP
A0A2U4CF05_TURTR/158-184             FALMNCPQCQRPFQKCQLNIHIVKECP
A0A1U7TT03_TARSY/157-183             FALTDCPQCQRPFQKCQINIHILKDCP
G1P0K0_MYOLU/157-183                 FALTNCLQCNRPLQKCQLNTHILQECP
TRAF6_BOVIN/158-184                  FALMSCPQCQRPFQKCHLNIHILKECP
A0A452SD59_URSAM/157-183             FALMNCPQCQRPFQKCQLNIHILKECP
A0A2K5ULJ8_MACFA/157-183             FALMDCPQCQHPFQKFHINIHILKDCP
A0A2K6NJ05_RHIRO/157-183             FALMDCPQCQRPFQKFHINIHILKDCP
A0A2K6BKS9_MACNE/157-183             FALMDCPQCQHPFQKFHINIHILKDCP
TRAF6_RAT/157-183                    FALVICPQCQRFFQKCQINKHIIEDCP
A0A2U3WKM7_ODORO/157-183             FALMNCPQCQRPFQKCLLNIHILKECP
A0A2Y9JQV9_ENHLU/157-183             FTLMNCPQCQRPFQKCQLNIHILKECP
A0A091CRB5_FUKDA/185-211             FALVNCSQCQHPFQKCQLNVHILKDCP
A0A1S3FGQ5_DIPOR/180-206             FALMNCPQCQHPLPKFQFNIHVLEDCP
E2RDE8_CANLF/157-183                 FALMNCLQCQRTFQKCQLNIHILKECP
A0A384A199_BALAS/158-184             FALMNCPQCQRPFQKCQLNIHIVKECP
TRAF6_HUMAN/157-183                  FALMDCPQCQRPFQKFHINIHILKDCP
#=GR TRAF6_HUMAN/157-183       SS    TSEEE-TTT--EEECCCHHHHHHHT-T
A0A2Y9PAB2_DELLE/177-203             FALMNCPQCQRPFQKCQLNIHIVKECP
A0A2Y9ERK4_PHYMC/177-203             FALMNCPQCQRPFQKCQLNIHIVKECP
A0A3Q7W437_URSAR/157-183             FALMNCPQCQRPFQKCQLNIHILKECP
A0A2K6EGK7_PROCO/157-183             FALMNCPQCQRPFQKCQINIHILKDCP
F7HMD7_MACMU/157-183                 FALVDCPQCQRPFQKFHINIHILKDCP
A0A2I3T972_PANTR/157-183             FALMDCPQCQRPFQKFHINIHILKDCP
A0A2R9CI00_PANPA/157-183             FALMDCPQCQRPFQKFHINIHILKDCP
G5B132_HETGA/159-185                 FALVNCSQCQRPFQKCQLNIHILTDCP
A0A2K5IN10_COLAP/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
H0V3B1_CAVPO/159-185                 FALINCLQCQRPIQKCQLNIHILKDCP
W5QCP4_SHEEP/158-184                 FALMSCPQCQRLFQKCHLNFHILKECP
H2NDP0_PONAB/239-265                 FALMDCPQCQRPFQKFHINIHILKDCP
H0WWF3_OTOGA/157-183                 FALMNCPQCQRPFQKCEINVHILKDCP
G1T2F3_RABIT/157-183                 FALVNCPQCQRPFQKCQINTHILKDCP
A0A384BRZ7_URSMA/157-183             FALMNCPQCQRPFQKCQLNIHILKECP
H2Q3F3_PANTR/157-183                 FALMDCPQCQRPFQKFHINIHILKDCP
A0A452ESI6_CAPHI/189-215             FALMSCPQCQRPFQKCHLNFHILKECP
A0A2K6EGL2_PROCO/157-183             FALMNCPQCQRPFQKCQINIHILKDCP
A0A2I2U6B5_FELCA/157-183             FALMNCPQCQRPFQKCQLNIHILKECP
A0A2K5DHG0_AOTNA/157-183             FALMDCPQCQRPFQKCQINIHILKDCP
F6W175_MACMU/157-183                 FALMDCPQCQHPFQKFHINIHILKDCP
A0A3Q2HK71_HORSE/157-183             FALMNCPQCQHPFQKCQLNIHMLKECP
A0A3Q7U5G5_VULVU/157-183             FALMNCLQCQRTFQKCQLNIHILKECP
A0A2K5WZD0_MACFA/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
A0A2R8ZJW9_PANPA/157-183             FALMDCPQCQPPFQKFHINIHIMKVCP
TRAF6_MOUSE/157-183                  FALVNCPQCQRPFQKCQVNTHIIEDCP
A0A452ESH1_CAPHI/158-184             FALMSCPQCQRPFQKCHLNFHILKECP
A0A384A1C9_BALAS/177-203             FALMNCPQCQRPFQKCQLNIHIVKECP
A0A2K6TWI5_SAIBB/171-197             FALMDCPQCQRPFQKCQINIHVLKDCP
A0A286XCF0_CAVPO/159-185             FALINCLQCQRPIQKCQLNIHILKDCP
G3QST5_GORGO/157-183                 FALMDCPQCQRPFQKFHINIHILKDCP
A0A337SQ77_FELCA/157-183             FALMNCPQCQRPFQKCQLNIHILKECP
I3M9G1_ICTTR/157-183                 FALMNCPQCQRAFQKCQFNIHILKDCP
A0A2U4CF07_TURTR/177-203             FALMNCPQCQRPFQKCQLNIHIVKECP
A0A452ETM2_CAPHI/158-184             FALMSCPQCQRPFQKCHLNFHILKECP
F7ES31_CALJA/157-183                 FALMDCPQCQRPFQKCQINIHILKDCP
A0A2Y9ERN8_PHYMC/158-184             FALMNCPQCQRPFQKCQLNIHIVKECP
A0A1A6HQX7_NEOLE/157-183             FALMTCTQCQRPFQKCQFNIHIMEDCP
A0A2K6MKD5_RHIBE/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
G3GZ05_CRIGR/135-161                 FALMNCPQCQRPFQKCHFHIHIIEDCP
G3TH24_LOXAF/157-183                 FALMDCPQCQRPFQKCHLNIHVLKECP
TRAF6_CERAT/157-183                  FALVDCPQCQRPFQKFHINIHILKDCP
TRAF6_PIG/158-184                    FALMNCPQCQRPFQKCQLNIHILKECP
A0A1U8C5B2_MESAU/157-183             FALMNCPQCQRPFQKCHFHMHIIEDCP
M3YK34_MUSPF/157-183                 FTLMNCPQCQRPFQKCQLNIHILKECP
A0A2K6DR01_MACNE/157-183             FALVDCPQCQRPFQKFHINIHILKDCP
A0A0D9QZK2_CHLSB/173-199             FALVDCPQCQRPFQKFHINIHILKDCP
A0A2Y9NZA9_DELLE/158-184             FALMNCPQCQRPFQKCQLNIHIVKECP
G1M5H7_AILME/157-183                 FALMNCLQCQRPFQKCQLNIHIHKECP
G3TWA4_LOXAF/157-183                 FALMDCPQCQRPFQKCHLNIHVLKECP
#=GC SS_cons                         TSEEE-TTT--EEECCCHHHHHHHT-T
#=GC seq_cons                        FALMsCPQCQRPFQKCplNIHILK-CP
//
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