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Database: Pfam
Entry: TRH
LinkDB: TRH
Original site: TRH 
#=GF ID   TRH
#=GF AC   PF05438.13
#=GF DE   Thyrotropin-releasing hormone (TRH)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_14384 (release 8.0)
#=GF GA   27.80 27.80;
#=GF TC   34.60 28.60;
#=GF NC   26.90 24.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Thyrotropin-releasing_hormone
#=GF RN   [1]
#=GF RM   10526628
#=GF RT   Thyrotropin-releasing hormone (TRH), a signal peptide of the
#=GF RT   central nervous system. 
#=GF RA   Heuer H, Schafer MK, Bauer K; 
#=GF RL   Acta Med Austriaca 1999;26:119-122.
#=GF RN   [2]
#=GF RM   12467901
#=GF RT   Neuroprotective effect and brain receptor binding of taltirelin,
#=GF RT   a novel thyrotropin-releasing hormone (TRH) analogue, in
#=GF RT   transient forebrain ischemia of C57BL/6J mice. 
#=GF RA   Urayama A, Yamada S, Kimura R, Zhang J, Watanabe Y; 
#=GF RL   Life Sci 2002;72:601-607.
#=GF DR   INTERPRO; IPR008857;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several thyrotropin-releasing hormone
#=GF CC   (TRH) proteins. Thyrotropin-Releasing Hormone (TRH;
#=GF CC   pyroGlu-His-Pro-NH2), originally isolated as a hypothalamic
#=GF CC   neuropeptide hormone, most likely acts also as a neuromodulator
#=GF CC   and/or neurotransmitter in the central nervous system (CNS).
#=GF CC   This interpretation is supported by the identification of a
#=GF CC   peptidase localised on the surface of neuronal cells which has
#=GF CC   been termed TRH-degrading ectoenzyme (TRH-DE) since it
#=GF CC   selectively inactivates TRH [1]. TRH has been used clinically
#=GF CC   for the treatment of spinocerebellar degeneration and
#=GF CC   disturbance of consciousness in humans [2].
#=GF SQ   188
#=GS A0A452QC57_URSAM/6-207    AC A0A452QC57.1
#=GS H2P9C6_PONAB/6-206        AC H2P9C6.1
#=GS A0A3Q1HVY8_ANATE/6-233    AC A0A3Q1HVY8.1
#=GS D6RFM1_HUMAN/6-202        AC D6RFM1.1
#=GS A0A2U3VLJ9_ODORO/6-203    AC A0A2U3VLJ9.1
#=GS A0A3Q2WFM2_HAPBU/6-235    AC A0A3Q2WFM2.1
#=GS A0A3Q1FSH4_9TELE/6-235    AC A0A3Q1FSH4.1
#=GS G3TEL3_LOXAF/5-91         AC G3TEL3.1
#=GS A0A0Q3URX9_AMAAE/84-304   AC A0A0Q3URX9.1
#=GS A0A151MK38_ALLMI/41-262   AC A0A151MK38.1
#=GS A0A3P8XLU3_ESOLU/77-173   AC A0A3P8XLU3.1
#=GS A0A3B4FT96_9CICH/6-212    AC A0A3B4FT96.1
#=GS K7FNZ1_PELSI/6-205        AC K7FNZ1.1
#=GS A0A3B3W1R9_9TELE/6-234    AC A0A3B3W1R9.1
#=GS A0A1S2ZCD1_ERIEU/130-188  AC A0A1S2ZCD1.1
#=GS A0A093ITK7_DRYPU/7-223    AC A0A093ITK7.1
#=GS A0A3B1JZN7_ASTMX/6-101    AC A0A3B1JZN7.1
#=GS M3Z0M6_MUSPF/10-211       AC M3Z0M6.1
#=GS A0A3Q3EL52_9LABR/6-235    AC A0A3Q3EL52.1
#=GS A0A2Y9J1E0_ENHLU/14-215   AC A0A2Y9J1E0.1
#=GS A0A2U9BZW3_SCOMX/205-390  AC A0A2U9BZW3.1
#=GS I3NCI2_ICTTR/6-204        AC I3NCI2.1
#=GS L9JDC1_TUPCH/126-198      AC L9JDC1.1
#=GS A0A226MKF2_CALSU/22-239   AC A0A226MKF2.1
#=GS A0A4D9EY34_9SAUR/5-226    AC A0A4D9EY34.1
#=GS A0A2K5QKB5_CEBCA/6-206    AC A0A2K5QKB5.1
#=GS C3ZWL4_BRAFL/143-309      AC C3ZWL4.1
#=GS A0A099YTJ5_TINGU/7-226    AC A0A099YTJ5.1
#=GS G3WTB0_SARHA/6-156        AC G3WTB0.1
#=GS W5MZE0_LEPOC/6-119        AC W5MZE0.1
#=GS A0A498MQI5_LABRO/6-193    AC A0A498MQI5.1
#=GS TRH_MOUSE/140-224         AC Q62361.2
#=GS A0A2K6BPH5_MACNE/6-207    AC A0A2K6BPH5.1
#=GS U3IIA1_ANAPP/7-227        AC U3IIA1.1
#=GS A0A3Q7U489_VULVU/6-204    AC A0A3Q7U489.1
#=GS A0A498LVT4_LABRO/38-227   AC A0A498LVT4.1
#=GS H3C5L3_TETNG/79-195       AC H3C5L3.1
#=GS A0A2K5CWE3_AOTNA/1-175    AC A0A2K5CWE3.1
#=GS TRH_DANRE/3-69            AC Q5EDF9.1
#=GS A0A060YLI9_ONCMY/80-192   AC A0A060YLI9.1
#=GS A0A2G8L3S2_STIJA/164-319  AC A0A2G8L3S2.1
#=GS G3R1J0_GORGO/4-197        AC G3R1J0.2
#=GS A0A401NUR8_SCYTO/20-171   AC A0A401NUR8.1
#=GS A0A3P8THN4_AMPPE/6-235    AC A0A3P8THN4.1
#=GS A0A3Q3AVY8_KRYMA/6-235    AC A0A3Q3AVY8.1
#=GS A0A087QJF5_APTFO/7-227    AC A0A087QJF5.1
#=GS A0A060XDV6_ONCMY/6-224    AC A0A060XDV6.1
#=GS A0A1A6HWM7_NEOLE/6-216    AC A0A1A6HWM7.1
#=GS A0A060YLI9_ONCMY/6-81     AC A0A060YLI9.1
#=GS A0A2Y9D5X8_TRIMA/5-202    AC A0A2Y9D5X8.1
#=GS A0A0P7X5Y1_SCLFO/5-216    AC A0A0P7X5Y1.1
#=GS A0A2I4BUQ6_9TELE/6-233    AC A0A2I4BUQ6.1
#=GS W5PU12_SHEEP/45-246       AC W5PU12.1
#=GS A0A093HSA7_STRCA/7-227    AC A0A093HSA7.1
#=GS A0A2U3Y0H3_LEPWE/6-87     AC A0A2U3Y0H3.1
#=GS W5MZE8_LEPOC/6-228        AC W5MZE8.1
#=GS Q4RJV2_TETNG/1-226        AC Q4RJV2.1
#=GS A0A2Y9MBV8_DELLE/19-215   AC A0A2Y9MBV8.1
#=GS A0A1V4JIY5_PATFA/7-225    AC A0A1V4JIY5.1
#=GS A0A3Q1BG00_AMPOC/6-235    AC A0A3Q1BG00.1
#=GS D2HGM5_AILME/6-207        AC D2HGM5.1
#=GS A0A3P9AS00_9CICH/6-233    AC A0A3P9AS00.1
#=GS A0A3B3H917_ORYLA/28-254   AC A0A3B3H917.1
#=GS E2RHA2_CANLF/6-205        AC E2RHA2.1
#=GS A0A2I2U1H2_FELCA/34-230   AC A0A2I2U1H2.1
#=GS U3KGX4_FICAL/7-224        AC U3KGX4.1
#=GS F7AY27_XENTR/6-214        AC F7AY27.1
#=GS H0XH21_OTOGA/6-206        AC H0XH21.1
#=GS A0A091DAC2_FUKDA/113-180  AC A0A091DAC2.1
#=GS L5K895_PTEAL/6-209        AC L5K895.1
#=GS A0A2K5LKS6_CERAT/6-207    AC A0A2K5LKS6.1
#=GS G3TEL3_LOXAF/88-184       AC G3TEL3.1
#=GS A0A096MUB8_PAPAN/6-207    AC A0A096MUB8.1
#=GS F1SPI7_PIG/6-206          AC F1SPI7.1
#=GS A0A091EPA8_CORBR/7-223    AC A0A091EPA8.1
#=GS A0A2Y9SMF2_PHYMC/6-203    AC A0A2Y9SMF2.1
#=GS A0A3Q2X5D7_HAPBU/6-212    AC A0A3Q2X5D7.1
#=GS A0A1L8GPJ3_XENLA/6-214    AC A0A1L8GPJ3.1
#=GS A0A2I2YGS0_GORGO/9-199    AC A0A2I2YGS0.1
#=GS A0A2K6P507_RHIRO/6-207    AC A0A2K6P507.1
#=GS A0A1L8GHM5_XENLA/6-212    AC A0A1L8GHM5.1
#=GS A0A0D9R9X9_CHLSB/2-203    AC A0A0D9R9X9.1
#=GS A0A3Q3XR37_MOLML/6-231    AC A0A3Q3XR37.1
#=GS A0A091GBU8_9AVES/7-227    AC A0A091GBU8.1
#=GS A0A3B4DHA1_PYGNA/8-228    AC A0A3B4DHA1.1
#=GS A0A340XQL8_LIPVE/119-306  AC A0A340XQL8.1
#=GS A0A091DAC2_FUKDA/6-120    AC A0A091DAC2.1
#=GS A0A384AZD9_BALAS/116-179  AC A0A384AZD9.1
#=GS F1QKW8_DANRE/3-70         AC F1QKW8.1
#=GS H3C5L3_TETNG/6-81         AC H3C5L3.1
#=GS A0A2K5XP22_MANLE/6-207    AC A0A2K5XP22.1
#=GS A0A2U9BZW3_SCOMX/109-180  AC A0A2U9BZW3.1
#=GS A0A091W0N2_NIPNI/7-227    AC A0A091W0N2.1
#=GS A0A3B1IFV0_ASTMX/77-186   AC A0A3B1IFV0.1
#=GS R4GCM4_ANOCA/7-107        AC R4GCM4.1
#=GS A0A3P8TIW7_AMPPE/6-235    AC A0A3P8TIW7.1
#=GS A0A2U3Z691_LEPWE/2-160    AC A0A2U3Z691.1
#=GS G3WTB1_SARHA/6-157        AC G3WTB1.1
#=GS G1ND92_MELGA/7-225        AC G1ND92.1
#=GS F7B653_HORSE/10-210       AC F7B653.2
#=GS A0A3P8Z7L5_ESOLU/6-224    AC A0A3P8Z7L5.1
#=GS A0A2I0LUB3_COLLI/6-225    AC A0A2I0LUB3.1
#=GS A0A2Y9MHD5_DELLE/6-202    AC A0A2Y9MHD5.1
#=GS A0A2K6EZQ5_PROCO/9-192    AC A0A2K6EZQ5.1
#=GS A0A3B1IFV0_ASTMX/6-81     AC A0A3B1IFV0.1
#=GS G5C711_HETGA/6-115        AC G5C711.1
#=GS A0A3B4UH03_SERDU/6-232    AC A0A3B4UH03.1
#=GS A0A2K6LC50_RHIBE/6-207    AC A0A2K6LC50.1
#=GS M4AS06_XIPMA/6-234        AC M4AS06.2
#=GS A0A2K5VYX3_MACFA/6-207    AC A0A2K5VYX3.1
#=GS A0A384CMJ5_URSMA/6-207    AC A0A384CMJ5.1
#=GS A0A3B4WNK0_SERLL/6-232    AC A0A3B4WNK0.1
#=GS K7E2N6_MONDO/6-156        AC K7E2N6.1
#=GS A0A3B3YF36_9TELE/6-234    AC A0A3B3YF36.1
#=GS G1P8T9_MYOLU/6-207        AC G1P8T9.1
#=GS A0A3Q0RHW4_AMPCI/6-211    AC A0A3Q0RHW4.1
#=GS TRH_RAT/6-223             AC P01150.1
#=GS G1Q2W0_MYOLU/6-202        AC G1Q2W0.1
#=GS A0A452G1W8_CAPHI/6-207    AC A0A452G1W8.1
#=GS A0A3P8Z7U9_ESOLU/12-230   AC A0A3P8Z7U9.1
#=GS A0A384AZD9_BALAS/6-120    AC A0A384AZD9.1
#=GS A6QM11_BOVIN/6-207        AC A6QM11.1
#=GS A0A1S3ENE1_DIPOR/6-122    AC A0A1S3ENE1.1
#=GS R7V6P3_CAPTE/16-192       AC R7V6P3.1
#=GS A0A3Q0DIP0_TARSY/1-136    AC A0A3Q0DIP0.1
#=GS A0A1D5R2T3_MACMU/1-164    AC A0A1D5R2T3.1
#=GS G3GS26_CRIGR/6-214        AC G3GS26.1
#=GS A0A401T5F1_CHIPU/6-223    AC A0A401T5F1.1
#=GS A0A091WIM9_OPIHO/7-227    AC A0A091WIM9.1
#=GS TRH_DANRE/68-176          AC Q5EDF9.1
#=GS H0ZJX5_TAEGU/7-224        AC H0ZJX5.1
#=GS R4GCM4_ANOCA/102-208      AC R4GCM4.1
#=GS H2TW65_TAKRU/6-234        AC H2TW65.2
#=GS A0A2U3V0B4_TURTR/6-202    AC A0A2U3V0B4.1
#=GS A0A3M0JK71_HIRRU/7-223    AC A0A3M0JK71.1
#=GS A0A218UDP5_9PASE/7-224    AC A0A218UDP5.1
#=GS W5MZE0_LEPOC/103-245      AC W5MZE0.1
#=GS M7C513_CHEMY/5-225        AC M7C513.1
#=GS A0A2K6UII9_SAIBB/6-206    AC A0A2K6UII9.1
#=GS F6QAC6_ORNAN/1-82         AC F6QAC6.1
#=GS A0A1S2ZCD1_ERIEU/6-148    AC A0A1S2ZCD1.1
#=GS F1QKW8_DANRE/68-176       AC F1QKW8.1
#=GS A0A093Q948_9PASS/7-227    AC A0A093Q948.1
#=GS A0A3P8X2Y2_CYNSE/6-241    AC A0A3P8X2Y2.1
#=GS Q1T735_ORYLA/6-232        AC Q1T735.1
#=GS A0A091IU67_EGRGA/7-227    AC A0A091IU67.1
#=GS A0A3Q0RJ44_AMPCI/6-224    AC A0A3Q0RJ44.1
#=GS A0A1S3MD66_SALSA/6-221    AC A0A1S3MD66.1
#=GS U3CCY5_CALJA/6-207        AC U3CCY5.1
#=GS K7E2N6_MONDO/150-189      AC K7E2N6.1
#=GS A0A3B4B595_9GOBI/6-220    AC A0A3B4B595.1
#=GS A0A3Q4HTY2_NEOBR/6-212    AC A0A3Q4HTY2.1
#=GS A0A3Q0CLB9_MESAU/6-211    AC A0A3Q0CLB9.1
#=GS A0A3B1JZN7_ASTMX/82-206   AC A0A3B1JZN7.1
#=GS G1SQS8_RABIT/7-210        AC G1SQS8.2
#=GS H2QNC9_PANTR/6-205        AC H2QNC9.1
#=GS B5XBV3_SALSA/6-224        AC B5XBV3.1
#=GS A0A0A0ACE4_CHAVO/7-227    AC A0A0A0ACE4.1
#=GS A0A2R9C4N0_PANPA/6-205    AC A0A2R9C4N0.1
#=GS A0A3P9PMS3_POERE/6-234    AC A0A3P9PMS3.1
#=GS A0A3B5ACP0_9TELE/6-235    AC A0A3B5ACP0.1
#=GS A0A3L8RWD3_CHLGU/7-224    AC A0A3L8RWD3.1
#=GS TRH_HUMAN/6-206           AC P20396.1
#=GS A0A402EFZ5_9SAUR/97-318   AC A0A402EFZ5.1
#=GS A0A3Q7X3N9_URSAR/6-207    AC A0A3Q7X3N9.1
#=GS TRH_MOUSE/6-125           AC Q62361.2
#=GS L9JDC1_TUPCH/6-134        AC L9JDC1.1
#=GS A0A3Q3MEZ9_9TELE/6-232    AC A0A3Q3MEZ9.1
#=GS G3NEZ6_GASAC/6-231        AC G3NEZ6.1
#=GS A0A1S3ENE1_DIPOR/99-190   AC A0A1S3ENE1.1
#=GS A0A210R0X1_MIZYE/18-557   AC A0A210R0X1.1
#=GS A0A3B3BSR8_ORYME/57-283   AC A0A3B3BSR8.1
#=GS A0A2D0QYL3_ICTPU/3-212    AC A0A2D0QYL3.1
#=GS A0A2K5HPM3_COLAP/6-207    AC A0A2K5HPM3.1
#=GS G1QZG4_NOMLE/6-207        AC G1QZG4.1
#=GS A0A3Q2E740_CYPVA/6-234    AC A0A3Q2E740.1
#=GS I3KKT6_ORENI/6-235        AC I3KKT6.1
#=GS H3AN56_LATCH/7-227        AC H3AN56.1
#=GS A0A1U7RQM3_ALLSI/6-227    AC A0A1U7RQM3.1
#=GS A0A226PNL5_COLVI/13-244   AC A0A226PNL5.1
#=GS G5C711_HETGA/112-178      AC G5C711.1
#=GS R0K990_ANAPL/7-227        AC R0K990.1
#=GS A0A3B3SMM3_9TELE/5-216    AC A0A3B3SMM3.1
#=GS TRH_CHICK/7-227           AC Q6ZXC3.2
#=GS A0A2I2YDN3_GORGO/6-207    AC A0A2I2YDN3.1
#=GS M3WV29_FELCA/6-202        AC M3WV29.3
#=GS A0A087Y6U4_POEFO/6-234    AC A0A087Y6U4.2
#=GS A0A091IDK5_CALAN/7-227    AC A0A091IDK5.1
A0A452QC57_URSAM/6-207               ........................................................................................................................................................................................................................................................................................LLLAMALT..LTVA.GIPGGRAQPEVAQ.Q.EAAMap.ehaGPDDL..LRQAQRlLFLREDLQR.LRGNQGD.LESEAQi.lQ............PNWLSKRQHPGKR-EGE.AEE---.-GVE..E..E..EE......E........GGAVGPHKRQH.PGRREDV..........................aAW.SDV.T.LQ..KRQHP.GRRS....--.--.--.--P..-LL.GY--TFTKRQHPGRRLV.....-----DS.KAQRSWEAEEe....................dEE..EE.GG...EPMPEKRQHPGKRAL-..------...GSPCGPGAA-.-.CGQAS...................................................................................................................................................................................................................................................................
H2P9C6_PONAB/6-206                   ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.erpGLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..lQ............SDWLSKRQHPGKR--EE.EEE---.-GVE.eE..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVPKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...DLMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
A0A3Q1HVY8_ANATE/6-233               ........................................................................................................................................................................................................................................................................................LLILASLV..LCNL.ALSGGQGIAGEDE.A.DHR-......TIDDI.iLQRAES.LLLRSILRK.MQDEDDR.NVGFSS...Q............PEWVTKRQHPGKRYSED.LEKRQH.PGRR..E..E..DE......D........DEYLDVQRRQH.PGKREDE...........................MH.SFT.E.LQ..KRQHP.GKRT....TS.GL.IS.DNP..--E.MFLSELSKRQHPGKRYL....vLHSKRQH.PGKRYSEDEDgee...............dwdvEG..D-.EN...PSELEKRQHPGKRFLD..NSSPDLg.tNSPCDVLEPT.S.CSKAS...................................................................................................................................................................................................................................................................
D6RFM1_HUMAN/6-202                   ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.ehpGLDDF..LRQVERlLFLRENIQR.LQGDQAS.Q---IF...Q............SDWLSKRQHPGKREEEE.EEG---.-VEE..E..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.AY--AVPKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...DLMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.-----ygqa...............................................................................................................................................................................................................................................................
A0A2U3VLJ9_ODORO/6-203               ........................................................................................................................................................................................................................................................................................LLLAMALT..LTVA.GILGGRAQPGVAQ.Q.EAAMaa.ehaGLDHL..LRQAERlLLLGEDLQR.LRGNQGK.PESEAQi.iQ............PDWLSKRQHPGKR-EGE.AEE---.-GVE..E..E..EE......E........GGAVSPHKRQH.PGRREDV..........................vAW.SDV.T.QQ..KRQHP.GRRS....--.--.--.---..SWL.GY--TFTKRQHPGRRLV.....-----DS.KAQRSWGP--......................EE..EE.EG...EPMPEKRQHPGKRAL-..------...GGPCGPGGA-.-.CGQAS...................................................................................................................................................................................................................................................................
A0A3Q2WFM2_HAPBU/6-235               ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.MVSGGQSMSAEDE.T.DRK-......TIDDI.iLERAET.LLLRSILKK.LQDEDGR.NDGYYS...Q............PEWVTKRQHPGKRYSDD.LEKRQH.PGRR..E..E..DE......D........EQYFDVQKRQH.PGKREDE...........................TH.SFL.E.LQ..KRQHP.GKRS....TA.SH.SS.DNP..--I.LLLSELSKRQHPGKRYL....vLHSKRQH.PGKRLLEDEDgdsd..............gdadAD..GE.ED...LAEMEKRQHPGKRFWD..NSSPDLg.tNSPCDVLDPA.S.CSKTS...................................................................................................................................................................................................................................................................
A0A3Q1FSH4_9TELE/6-235               ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.AVSGGQGIPAEDE.T.DRR-......TIDDM.iLQRAEN.LLLRSILKK.LQEEDGR.NEGFYS...L............PEWVTKRQHPGKRYGED.LEKRQH.PGRR..E..E..DE......D........EQYLDVQKRQH.PGKREDE...........................MH.SFM.E.LQ..KRQHP.GKRS....AA.EH.NS.DDP..--L.VLLSELSKRQHPGKRYL....vLHSKRQH.PGKRHPEDEDddgd..............wdadAD..GE.ED...LSELEKRQHPGKRFWD..NSSPDLg.tNSPCDVLDAA.S.CSKTS...................................................................................................................................................................................................................................................................
G3TEL3_LOXAF/5-91                    .......................................................................................................................................................................................................................................................................................w--LLLALA..LTLT.CVPGCRAQPEVAQ.K.EAVTaa.erpGLDDL..LRQAERlLLLREDLQR.LRADRGE.RDTEPQt.lQ............LDWLSKRQHPGKT----.------.----..-..-..--......-........-----------.-------...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----vgp................................................................................................................................................................................................................................................................
A0A0Q3URX9_AMAAE/84-304              .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LCSV.CLKERSPFPEGSE.N.TGRS......LLDDI..LQRSDS.LILHSVFKK.AEKEGEI.NKESNA..pL............PEWLSKRHHLGKKYLSE.LEKRQH.PGKR..D..V..EE......D........TSYGDIQKRQH.PGKREIEd.........................dLD.SSL.E.LK..KRQHP.GRRS....LL.EQ.DA.DNP.sSQL.TYLNELSKRQHLGRRYL.....-IYKYQH.PSKRGWND--......................EV..DL.ND...-RYREKHQHLGKKHWN..FDSPDD...AGPCNFQESF.T.CNKGS...................................................................................................................................................................................................................................................................
A0A151MK38_ALLMI/41-262              ........................................................................................................................................................................................................................................................................................LLLLLSLT..LSGI.CLNLGQPTLDGGE.N.GERS......HLDDI..LQRAES.ILLKSILKK.VEEEEEL.NKEPDA..sE............PDSLSKQQHPGKRFFNE.LEKRQH.PGKR..E..D..GE......E........ALYGDIQKRQH.PGKREEDd.........................dLD.RYL.E.LQ..KRQHP.GKRS....LW.DQ.YV.DAP.gIQL.TYLNELSKRQHPGKRYL.....VYAKRQH.PGKRGWED--......................EL..DL.GE...-QDLEKRQHPGKRFSD..SESPDY...AAPCDLQDDF.N.CSKGS...................................................................................................................................................................................................................................................................
A0A3P8XLU3_ESOLU/77-173              .............................................................................................................................................................................................................................................................................ttpwymgdntl--------..----.-------------.-.----......-----..------.---------.-------.------...-............---VHGRQHPGTR----.ATGRQH.PGTR..A..T..TPw....yM........GDNTLVHGRQH.PGTRATTp.........................wYK.GDN.TlVH..GQPHP.GTRV....TT.TW.YK.SDH..TLV.------HWRQHPGT---.....-------.----------......................--..--.--...----------------..------...----------.-.-----h..................................................................................................................................................................................................................................................................
A0A3B4FT96_9CICH/6-212               ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.MVSGGQSMSAEDE.T.DRK-......TIDDI.iLERAET.LLLRSILKK.LQDEDGR.NDGYYS...Q............QEWVTKRQHPGKRYKED.------.----..-..-..-E......D........EQYFDVQKRQH.PGKREDE...........................TH.SFL.E.LQ..KRQHP.GKRS....TA.GH.SS.DNP..--I.LLLSELSKRQHPGKRYL....vLHSKRQH.PGNDG--DAD......................AD..GE.ED...LAEMEKRQHPGKRFWD..NSSPDLg.tNSPCDVLDPA.S.CSKTS...................................................................................................................................................................................................................................................................
K7FNZ1_PELSI/6-205                   ........................................................................................................................................................................................................................................................................................LLLLLSLT..LSSA.CVNLGQPIPEANE.N.GERS......HLDDI..LQRAES.IILRSILKK.AEEEEET.NKEPSA..sQ............PGWFSKRQHPGKRFLTD.LEKRQH.PGKR..E..E..DD......D........-----------.-------...........................--.SDL.E.LQ..KRQHP.GRRS....LW.DQ.YM.DIP.sTQL.AYLHELSKRQHPGKRYL.....IYTKRQH.PGKRSWDD--......................EL..DL.RD...-QDMEKRQHPGKRYVD..SESTDY...DAPCDFQESF.N.CSKGS...................................................................................................................................................................................................................................................................
A0A3B3W1R9_9TELE/6-234               ........................................................................................................................................................................................................................................................................................LLVLASFV..ICNL.AVCDGQGLPAEDE.M.DRST......TIDNL.mLQRAQS.LLLRSILKK.LQDGDGK.NDGILS...Q............PQWVTKRQHPGKRYFED.LEKRQH.PGRR..E..V..VD......D........EQFWDMQKRQH.PGKREDE...........................MH.SFT.E.FQ..KRQHP.GKRS....TT.GH.IP.DSP..--V.VVLSELSKRQHPGKRYL....vLHSKRQH.PGKRLLEDEDgea................dwtED..GE.ED...MSELEKRQHPGKRFWD..NSSPELs.tSSPCDVLDSD.S.CSKTS...................................................................................................................................................................................................................................................................
A0A1S2ZCD1_ERIEU/130-188             .......................................................................................................................................................................................................................................................................................q--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................--.---.-.--..-----.----....--.--.--.---..---.-------KRQHPGRRLA.....---NPES.LGWGVAE--E......................EG..RE.EG...EQEPEKRQHPGRRAL-..---GAL...DAPCGSRSA-.-.-----cil................................................................................................................................................................................................................................................................
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A0A3B1JZN7_ASTMX/6-101               ........................................................................................................................................................................................................................................................................................LILLSFLA..LCNL.SGTQCQNIPAAEE.EpEERP......SLEEI..LQRAQT.LLMRAIIKK.MEEEGNA.EETFAP...Q............SEWLEKRQHPGKR----.----QH.PGRR..E..E..EE......E........EEDGD------.-------...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----yp.................................................................................................................................................................................................................................................................
M3Z0M6_MUSPF/10-211                  ........................................................................................................................................................................................................................................................................................LLLAVALT..LTVA.GFPGGRAQPEVAQ.Q.EAAMaa.ehaGVDDL..LRQAERlLLLREDVQR.LRGNQDD.RESESQi.iQ............PDWLSKRQHPGKR-EGD.AEE---.-GVE..E..E..EE......E........GGAVGPHKRQH.PGRREDV..........................aAW.SDV.T.QQ..KRQHP.GRHP....--.--.--.---..SWL.GY--TFTKRQHPGRRLV.....-----DS.KAQGSWEAEEe....................eEE..EE.EG...EPIPEKRQHPGKRAL-..------...GGPCGPGGD-.-.CGQAS...................................................................................................................................................................................................................................................................
A0A3Q3EL52_9LABR/6-235               ........................................................................................................................................................................................................................................................................................LLILASLV..VYNL.NVCVGQGLPAEDE.T.DRV-......TIDDI.iLQRAES.LLLRSILSK.MQEEDGR.NEGSSS...Q............TAWVSKRQHPGKRYIED.LEKRQH.PGRR..E..E..DE......D........EQYLDVQRRQH.PGKREDA...........................MH.SLM.E.LQ..KRQHP.GKRF....TT.GH.NS.ENP..--V.MLLSELSKRQHPGKRYL....vLHSKRQH.PGKRQPEDEDsegd..............wdadTD..GD.ED...LAELEKRQHPGKRFWD..NSSPDIg.tNSPCDVLEPT.S.CSKTS...................................................................................................................................................................................................................................................................
A0A2Y9J1E0_ENHLU/14-215              ........................................................................................................................................................................................................................................................................................LLLAMALT..LTVA.GFPGGSAQPEVAQ.Q.EAAMaa.ehaGLDDL..LHQAERlLLLREDVQR.LRGNQGD.PESESQi.iQ............PDWLSKRQHPGKR-EGE.AQE---.-GVE..E..E..EE......E........GGAVGPHKRQH.PGRREDV..........................aAW.SDV.T.QQ..KWQHP.GGRP....--.--.--.---..SWL.GY--TFTKRQHPGRRLV.....-----DS.KAQRSWEAEEe....................eEE..EE.EG...EPIPEKRQHPGKRAL-..------...GGPCGPGEA-.-.CGQAS...................................................................................................................................................................................................................................................................
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I3NCI2_ICTTR/6-204                   ........................................................................................................................................................................................................................................................................................LLLTLALT..LTLT.GSPGGRAQPQAAQ.Q.EAEMaa.ehpALDDL..LRQAEGfLLLQDDIQR.LRGDLGQ.P-SESL...Q............PDSLSKRQHPGKR-EEE.AEE---.-GVE..E..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................aWSlDRT.Q.QR..KRQHP.GRRS....--.--.--.--P..-WL.GP--ADTKRQHPGRRLV.....-----DA.QVQGSWREEQ......................EE..DAgEG...TPRVERRQHPGKRAL-..------...GGPCAPQGA-.-.C----aps................................................................................................................................................................................................................................................................
L9JDC1_TUPCH/126-198                 .................................................................................................................................................................................................................................................................................appdrrw--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................--.---.-.--..-----.----....--.--.--.---..---.-LESAVAKRQHPGRRLV.....-----DP.KTHRSWEEEE......................ET..EE.EEgdgGLLPEKRQHPGKRAP-..------...GVPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
A0A226MKF2_CALSU/22-239              .......................................................................................................................................................................................................................................................................................p-VLLLCLT..LSGV.CLNGRQPPPEASE.N.MRS-......SLDDI..SQRSGS.HMLQSVLKK.VEKKEEM.NKELNA..pL............PQWLYKRQHPGKRYVSD.LEKRQH.PGKR..D..A..EE......E........TSYADIQKIQH.LGKTEDY...........................LA.NYP.E.LK..KRQHP.GRRS....LW.DQ.ST.GIP.sSQL.TYLNELSKTQHPGRRYL.....-MYKHQH.PSKRGWND--......................EL..DL.SG...-QNWEKHQHSRKRHRD..SDSLDY...AGPCDLQQSA.I.CNKGS...................................................................................................................................................................................................................................................................
A0A4D9EY34_9SAUR/5-226               .......................................................................................................................................................................................................................................................................................r-LLLLSLT..LSSV.CVSLEQPIPEANE.N.GDRS......HLDDI..LQRAES.TILRSILKK.AEEEEET.NKEPSA..pQ............PDWFSKRQHPGKRFPSD.LEKRQH.PGKR..E..D..EE......E........VSYGETQKRQH.PGKREEDd.........................dLD.SDM.E.LQ..KRQHP.GRRS....LW.DQ.YV.DIP.sTQL.AYLNELSKRQHPGKRSL.....IYNKSQH.PGKRSWDD--......................EL..DL.GN...-QDMEKRQHPGRRYVD..SESPDY...DAPCDLQDSF.N.CSKGS...................................................................................................................................................................................................................................................................
A0A2K5QKB5_CEBCA/6-206               ........................................................................................................................................................................................................................................................................................LLLALALT..LNLI.GVPGGGAQPEAAQ.Q.EAVTva.erpGLDDL..LRQVERlLFLRENILR.QQGDQGE.HSASQI..lQ............PDWLSKRQHPGKR-EEE.GEV---.-GVE..E..E..EE......E........AGAMGPHKRQH.PGRREDEa.........................sWS.VDA.A.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVTRRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.KE...ELMPEKRQHPGKRAV-..EGSCEP...QGAC------.-.-----gqav...............................................................................................................................................................................................................................................................
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G3WTB0_SARHA/6-156                   .....................................................................................................................................................................................................................................................................................llp--LLLSLA..LSSF.SINLGQPAAAEAD.S.EEKG......RLEEI..LQRAEN.LFLQSNLQK.LEEEGEN.NSDLQA..pP............LDWLVKRQHPGKREEED.EGE---.--EE..E..A..GD......E........GTTIEIHRRQH.PGKREEE..........................tWE.EDG.K.EQ..KRQHP.GRRA....SW.LK.DS.E--..---.---GDISKRQHPGRRSL.....-------.----------......................--..--.--...----------------..------...----------.-.-----g..................................................................................................................................................................................................................................................................
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A0A498MQI5_LABRO/6-193               .......................................................................................................................................................................................................................................................................................v-IILASLT..VSLS.PVIQCQALPGEGD.P.----......SLDEL..FQRAES.LLIRSILTQ.MEDENNA.N---GE...Q............TEWLEKRQHPGKR----.----QH.PGKR..E..D..AE.....yE........DEASALQKRQH.PGKREEE...........................--.-DS.A.RL..RRQHP.GKRL....TL.EQ.MMlEEP..---.TAQSELAKRQHPGKRYL....mLLHKRQH.PGRRELQE--......................--..AA.ED...FSDLAKRQHPGKRLCE..------...----------.-.-----dwevagcdqas........................................................................................................................................................................................................................................................
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A0A2K6BPH5_MACNE/6-207               ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.erpGLDDL..LRQVERvLFLRENIQR.LQGDQGE.HSASQI..lQ............SDWLAKRQHPGKREEEE.EEG---.-VEE..E..E..EE......E........AGAVGPHKRQH.PGRREDEa.........................sWS.VNV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVTKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...ELMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
U3IIA1_ANAPP/7-227                   .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LSGV.CLNGGQPLPEASE.N.MGRR......PLDNI..LQRSES.FILQSVLKK.AEKKEEM.NKELNA..pL............PEWLSKRQHPGKRYISD.LEKRQH.PGKR..D..V..KE......E........ASYGDIQKRQH.PGKREVEd.........................dLA.SYL.E.LK..KRQHP.GRRS....LW.DQ.HV.DIP.sARL.TYLNVLSKRQHPGRGYL.....-MHKHQH.PSKRGWND--......................EL..DI.SD...-HDGEKRQHPGKRHWD..TDNPDY...AGPCDLQESS.T.CNTGS...................................................................................................................................................................................................................................................................
A0A3Q7U489_VULVU/6-204               ........................................................................................................................................................................................................................................................................................LLLAMALT..LTVA.GIPGGSAQPEVAQ.Q.EAATaa.ehaDLDDL..LRQAER.LLLREDLQR.LRGNQGN.PEPESQt.vQ............TNWLSKRQHPGKR-EGE.AEE---.-GVE..E..E..EE......E........GLAVDPHKRQH.PGRREDA..........................aAW.SHG.T.QQ..KRQHP.GRRS....--.--.--.---..SWL.EY--TLTKRQHPGRRLV.....-----DP.KAQMSWEAEE......................EE..GE.EG...ELMPEKRQHPGKRAL-..------...GGPCGTGGA-.-.CGQA-r..................................................................................................................................................................................................................................................................
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A0A2K5CWE3_AOTNA/1-175               ....................................................................................................................................................................................................................................................................................eavt--------..----.-------------.A.AERP......GLDDL..LRQAERlLFLRENILR.LQKDQGE.HSASQI..lQ............PNWLSKRQHPGKR-EEE.EE----.VGVE..E..Q..EE......E........GRAVGPHKRQH.PGRREDEa.........................sRS.VNA.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVTRRQHPGRRLA.....-----DP.KAQRNWEEEE.....................eEK..ER.KE...ELMPEKRQHPGKRAV-..------...GGSCEPQGA-.-.CG---qav................................................................................................................................................................................................................................................................
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G3R1J0_GORGO/4-197                   ..................................................................................................................................................................................................................................................................................svglic----LCLA..LTHT.EPPG-----ARVQ.X.XXXP......GLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..fQ............SDWLSKRQHPGKREEKE.-EE---.-GVE.eE..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QY..KRQHP.GRRS....--.--.--.--P..-WL.AY--AVPKRQHPGRRLA.....-----DP.KSQRSWEEEE.....................eEE..ER.EE...DLMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
A0A401NUR8_SCYTO/20-171              ......................................................................................................................................................................................................................................................................................df--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----KRQHPGKRSEEE.FEKRQH.PGKR..E..EgaSE......E........GAYLAAEKRQH.PGRRGLD...........................-G.AAL.E.IE..TRQHP.GRRS....PF.AQ.YA.GEN..---.AFLGELAKPQRPADMSL.....LYSKRQH.PGRRSWED--......................ES..DS.GE...REWLERGQSPSRPYPEagSSSTEL...SSPCELQEPV.S.CGKP-s..................................................................................................................................................................................................................................................................
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G1Q2W0_MYOLU/6-202                   ........................................................................................................................................................................................................................................................................................LLLALALT..LTLT.GVPGGRAQLEVDQ.Q.EAAMaa.ehpALRDL..LRQAGHlLLLREDLQR.LQGDQGN.RESGS-...-............-NGLSKRQHPGKR-EEE.AEE---.-GVE..D..E..EE......E........GGAVGPHKRQH.PGPWENAa.........................aWS.VDV.T.PQ..KRQHP.GRRS....--.--.--.---..FWL.GY--TFTKRQHPGRRLV.....-----DP.KAQRSWEEEE.....................eEE..EE.EG...ELMPEKRQHPGKRAL-..------...GGPCGLQGD-.-.CGQAS...................................................................................................................................................................................................................................................................
A0A452G1W8_CAPHI/6-207               ........................................................................................................................................................................................................................................................................................FLLAMALT..LTLT.SVPGGRAQLDVAQ.Q.DVDLse..qqGLEDL..LQQAERlLLLREDLQR.LREDQDD.SVSESQi.fQ............PDWFSKRQHPGKREEEE.ADE---.-GVE..G..E..EE......E........GGAVGLRKRQH.PGRRDDVa.........................aWA.VDA.G.QQ..KRQHP.GRRA....--.--.--.---..SWL.GY--AVTKRQHPGRRLV.....-----DP.RPQRSWEEAG.....................eDE..DE.GG...ELMSEKRQHPGKRAL-..------...GSPCGPRGP-.-.CGQAS...................................................................................................................................................................................................................................................................
A0A3P8Z7U9_ESOLU/12-230              ........................................................................................................................................................................................................................................................................................LIILASFA..VCNL.TLARAQGIPPEED.T.GDQQ......TIDDI.iLQRAES.LLLRSILKK.IEDEDGA.NDGQFS...Q............SVWMVKRQHPGKRYQDE.LEKRQH.PGKR..E..E..DE......D........EDYMEVQKRQH.PGKREDE...........................ID.SFV.E.LQ..RRQHP.GKRS....IL.EQ.IT.ENP..---.AFLSELSKRQHPGKRNA....iMYSKRQH.PGRRDVDD--......................ES..DP.VD...LQELEKRQHPGKRYWD..NMSQDFs.aNNPCDVMDP-.G.CSKAN...................................................................................................................................................................................................................................................................
A0A384AZD9_BALAS/6-120               ......................................................................................................................................................................................................................................................................................fl--LAMVLTltLSGV.RAQPEVAQQEAAI.A.AEQL......GLDDL..LGQAEPlLLLREDLQR.LREDQED.SESESQi.fQ............PHWLSKRQHPGKR-EEE.LEE---.-GVE..E..E..EE......E........GGAVGPHKRQH.PGRRS--...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----swl................................................................................................................................................................................................................................................................
A6QM11_BOVIN/6-207                   ........................................................................................................................................................................................................................................................................................FLLAMALT..LTLT.GVPGGRAQLDVAQ.Q.EADLse..qqGLEDL..LRQAERlLLLREDLQR.LREDQDD.SVSESQi.fQ............PDWFSKRQHPGKREEEE.ADE---.--AV..E..G..EE......E........GGAAGLHKRQH.PGRRGDVa.........................aWA.VDA.G.QQ..KRQHP.GRRA....--.--.--.---..SWL.GY--AVTKRQHPGRRLV.....-----DP.RAQRSWEEAG.....................eDE..DE.GG...ELMSEKRQHPGKRAL-..GSLCGP...RGPCG-----.-.-----qasl...............................................................................................................................................................................................................................................................
A0A1S3ENE1_DIPOR/6-122               ........................................................................................................................................................................................................................................................................................LLLVLALT..LTLT.SVPGGRAQPEAAQ.E.EAALe...hpGLDAL..QRQAERlLLLREDLHR.LRGDLGE.LSKSLVl.rR............LDRLSKRQHPGKRT-AA.VGG---.-GLEeaE..E..EA......E........GGPVAPHKRQH.PGRRS--...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----pw.................................................................................................................................................................................................................................................................
R7V6P3_CAPTE/16-192                  ...................................................................................................................................................................................................................................................................illslalafipavsfasdelv--------..----.-------------.-.----......-----..------.---------.-------.----DE...E............ASEMDKRRGWGKRSDSE.MDKRRG.WGKR..S..F..DE......D........S--EEVAKRRG.WGKRSEA...........................IN.LDE.V.EE..SIAEM.DKRR....GW.GK.RS.ELE..---.AMQSEFAKRRGWGKRADd...mEILKRRG.WGKRSEDANEmd..................krRG..WG.KR...SLEAEKRRGWGKRSPK..I-----...----------.-.-----eefseivdcqevkeki...................................................................................................................................................................................................................................................
A0A3Q0DIP0_TARSY/1-136               .....................................................................................................................................................................................................................................................................................sqt--------..----.-------------.-.----......-----..------.---------.-------.-----L...Q............PDWLSKRQHPGRR-EEE.AEE---.-GVE..E..E..EE.....eE........GGAVGPRKRQH.PGRREDEa.........................sWL.VNA.T.QH..KWQHP.GRHS....--.--.--.---..SWL.GY--AVTKRQHPGRRLV.....-----DP.KFQRSWEEEE.....................eEE..ER.EE...ELVPEKRQHPGKRAL-..------...GGPCGPQGT-.-.CG---las................................................................................................................................................................................................................................................................
A0A1D5R2T3_MACMU/1-164               ........................................................................................................................................................................................................................................................................................--------..----.-------------.-.----......---DL..LRQVERvLFLRENIQR.LQGDQGE.HSASQI..lQ............SDWLAKRQHPGKREEEE.EEG---.-VEE..E..E..EE......E........AGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVTKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...ELMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
G3GS26_CRIGR/6-214                   ........................................................................................................................................................................................................................................................................................LLLSLALI..FTLT.GIPESCALPEAAQ.E.EGAV......Q----..-MQPER.RFLRKDLQR.VRGDLGA.A-----...L............DSWITKRQHPGKREEEE.ETE---.AEER..G..D..LG......E........GGAWSPHKRQH.PGRRANQdkyswveaedsdwvsptrlphffleswYL.DQL.D.QV..KRQHP.GRRS....--.--.--.-FP..---.WMESDVTKRQHPGRRFI.....-----DP.NFQRSWED--......................KE..EG.EG...VPMPEKRQHPGKRAL-..------...GQPCGPRGA-.-.CGQT-d..................................................................................................................................................................................................................................................................
A0A401T5F1_CHIPU/6-223               ...................................................................................................................................................................................................................................................................................fllvg-----YLS..LHKS.VTASGHTAAGEAGlG.AEAE......PLEEM..LQRAEA.VLIHSILEG.GRNDDAL.GSDSP-...P............AERVLKRQHPGKRLVGD.LEKRQH.PGKR..QpgQ..DE......E........DGGWAPEKRQH.PGRRELD...........................-G.VPL.E.VQ..ARQHP.GRRS....AY.EP.LP.GEStaRQLdTFLGELSKRQHPGKRSV.....--MYGQR.PGHWSWQENG......................DD..--.SG...ESQYNSPQYL---EAA..GSSSEF...LSPCDLQESG.S.CSKV-n..................................................................................................................................................................................................................................................................
A0A091WIM9_OPIHO/7-227               .......................................................................................................................................................................................................................................................................................q-LLLLCLT..LCGV.CLNGGQLLPEGSE.N.MGRS......PFNDI..LQRSES.LILQSVLTK.AEKEEEM.NKESNA..pL............PEWLSKRQHPGKKYLSD.LQKRQH.PGKR..D..V..EE......D........PSYGGIQKRQH.PGKREIEd.........................nLD.GYL.E.LK..KRQHP.GRRS....LT.DQ.YA.DVP.sAQL.TYLNDFSKRQHPGRRYL.....-MYKRQH.PSKRGWND--......................EV..DL.NP...-QYGEKHQHPGKRQWN..SDSPDG...AGPCNFQESF.T.CNKGS...................................................................................................................................................................................................................................................................
TRH_DANRE/68-176                     ........................................................................................................................................................................................................................................................................................--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-------KRQH.PGKREED...........................LE.PEV.E.MErwRRQHP.GKRA....PL.DLgML.EDP..---.TALSELSKRQHPGKRYL....mLLHKRQH.PGRRELQEA-......................--..-D.GD...SAELEKRQHPGKRRC-..------...----------.-.-----egwadagcgllelldts..................................................................................................................................................................................................................................................
H0ZJX5_TAEGU/7-224                   .......................................................................................................................................................................................................................................................................................p-LLLLCLT..SCGV.CFNGGHLLPEESE.N.MGKV......PLDDT..LQRSES.LILQSVLKK.AEKEEEI.NKELNA..pL............LQRLSKRQHPGEKYLNN.LKKRQH.PGKR..D..V..EE......E........TFYGDIQKRQH.PGKREMEd.........................dLD.VYL.E.LK..RQQPP.GIKS....LL.DQ.FA.YSP.rAQL.TYMNELSKREHLGRRYL.....-MFKHQH.PSKRGWNY--......................EV..DV.YG...----EKRQHPGKRHWN..FDRSDD...TGPCNFQESF.T.CHKGS...................................................................................................................................................................................................................................................................
R4GCM4_ANOCA/102-208                 ....................................................................................................................................................................................................................................................................................gdgf--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................-N.LYS.E.LQ..KRQHP.GRRS....LW.EQ.YL.NTP.nSQL.AYLNELSKRQHPGKRYL.....AYSKRQH.PGKRSWDE--......................--..ET.EE...VENLEKRQHPGKRYLS..SESPDY...TAPCDLQDSL.E.CSKGS...................................................................................................................................................................................................................................................................
H2TW65_TAKRU/6-234                   ........................................................................................................................................................................................................................................................................................LLILASVV..VCNL.IVCGGQGIPDEDE.L.DRM-......AIDDI.iLQRAEG.LLLQSILRK.MQSEDGR.S-GESS...Q............IDWVTKRQHPGKRYMED.LEKRQH.PGRR..E..E..SE......D........D--LDVQKRQH.PGKRDDE...........................MH.SLV.E.IQ..RRQHP.GKRT....MM.GH.VT.ENP..--V.LLFSELSKRQHPGKRYL....vLHTKRQH.PGKRHFEEEDidgew............dadanAD..DV.ED...LAEPEKRQHPGKRFWD..NSNPDLg.tNNPCDVLDHT.S.CSKTS...................................................................................................................................................................................................................................................................
A0A2U3V0B4_TURTR/6-202               ........................................................................................................................................................................................................................................................................................FLLAIVLT..LTLT.GVPGGRAQPEVAQ.Q.EAAMaa.eqlGLDDL..LRQAEPlLLLREDLQR.LRENQED.SESESQi.fQ............PYWLSKRQHPGKR-EEE.SEE---.-GVE..E..E..EE......-........GGAVGPHKRQH.TGRQEEVa.........................aWP.EDI.S.QQ..KRQHP.GRRS....--.--.--.---..SWL.GY--TFTKRQHPGRRLA.....-----DP.QAQSSWEE--......................-E..EE.EG...ELMPEKRQHPGKRAL-..------...GSPCGLWGS-.-.CGQAS...................................................................................................................................................................................................................................................................
A0A3M0JK71_HIRRU/7-223               .......................................................................................................................................................................................................................................................................................p-LLLLCLT..SCGV.CFNGGH-LPEENE.N.MGKS......LLNDT..LQGSES.LILQSALKK.AEKEEEI.NKESNT..pL............LQWLSKRQHPGKKYLSN.LEKRQH.PGKR..D..V..EE......E........TSYGDIQKRQH.PGKREMEd.........................dLD.VYL.E.LK..RQQPP.GRKS....LL.DQ.SA.NSP.rAQP.TYMSESSKREHPGRRYP.....-MYKHQH.PSKRGWNY--......................EV..DL.YG...----EKRQHPGKRYWN..SDSSDD...TGPCNFQEPF.T.CHKG-r..................................................................................................................................................................................................................................................................
A0A218UDP5_9PASE/7-224               .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LCGV.CFNGGHLLPEESE.N.MGKI......PLDDI..LQRSES.LILQSVLKK.AEKEEEI.NKESNA..pL............LQQLSKRQHPGKKYLNN.LEKRQH.PGKR..D..V..EE......E........TFYGDIQKRQH.PGKREMEd.........................dLD.VYL.E.LK..RQLPP.GRKS....LL.DQ.FA.YSP.rAQI.TYMNKLSKREHLGRRYL.....-MFKHQH.PSKRGWNY--......................EV..DV.YS...----EKRQHPGKRHWN..FDRSDD...TGPCNFQESF.T.CHKGS...................................................................................................................................................................................................................................................................
W5MZE0_LEPOC/103-245                 .....................................................................................................................................................................................................................................................................................ryp--------..----.-------------.-.----......-----..------.---------.-------.------...-............----------------D.FEKRQH.PGRR..E..E..DD......-........-DYFEEQKRQH.PGKREDE...........................TD.DYV.E.LQ..RRQHP.GKRS....LM.DQ.YS.DAT.dSQM.GYQSDMSKRQHPGKRYL.....SYNKRQH.PGRRELEN--......................EL..DA.GD...LQDLEKRQHPGKRYWD..IKSPDYi.nNLPCDIKDPV.K.CNKAS...................................................................................................................................................................................................................................................................
M7C513_CHEMY/5-225                   .......................................................................................................................................................................................................................................................................................r-LLLLSLT..FSSV.CVSLGQPIPEANE.N.GDRS......HLDDI..LQRAES.IILRSILKT.AEEGEET.NKETSA..pQ............PDWFSKRQHPGKRFPSD.LEKRQH.PGKR..E..D..EE......E........VSYGETQKRQH.PGKREEDd.........................dLD.SDM.E.LQ..KRQHP.GRRS....LW.DQ.YV.DIP.hTQL.AYLNELSKRQHPGKRSL.....IYNKRQH.PGKRSWDD--......................GL..DL.GN...-QDLEKRQHPGRRYMD..SESPDY...DAPCDRLDSF.N.CSS--f..................................................................................................................................................................................................................................................................
A0A2K6UII9_SAIBB/6-206               ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTva.erlGLEDL..LRQAERlLFLRENILR.QQGDQGE.HSASQI..lQ............PDWLSKRQHPGKR-EEE.EE----.VGVE..E..E..KE......E........GGAVGPHKRQH.PGRREDEa.........................sWS.VDA.T.QH..KRQHP.GRRS....--.--.--.---..HWL.GY--AVTRRQHPGRRLV.....-----DP.KAQRSWEEGE.....................eEE..ER.KE...ELMPEKRQHPGKRAV-..------...GGSCEPQGA-.-.CSQ--av.................................................................................................................................................................................................................................................................
F6QAC6_ORNAN/1-82                    ......................................................................................................................................................................................................................................................................................dd--------..----.-------------.-.----......-----..------.---------.-------.------...-............---LVKRQHPGKREEEE.EEE---.-GEE..S..D..SE......E........ELLLEAQKRQH.PGRRDED..........................dSE.AFG.E.WQ..KRQHP.GRRS....P-.--.--.---..-WD.RY--NVEKRQHPGKRYL.....-------.----------......................--..--.--...----------------..------...----------.-.-----d..................................................................................................................................................................................................................................................................
A0A1S2ZCD1_ERIEU/6-148               .......................................................................................................................................................................................................................................................................................w--LLLLVA..LDLM.GVPGVLAQPNMAQ.Q.EASMvadrpgVLNDL..LHQAER.LLLQADPQE.LQAEMDG.QWSDPQa.dQ............PHWLTKRQHPGRREEKE.VEE-VE.EEEE..E..T..AA......A........GGAVGPHKRQH.PGRREQG...........................--.-DH.T.PQ..KRQHP.GRRL....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----anpeslgwg..........................................................................................................................................................................................................................................................
F1QKW8_DANRE/68-176                  ........................................................................................................................................................................................................................................................................................--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-------KRQH.PGKREED...........................LE.PEV.E.MErwRRQHP.GKRA....PL.DLgML.EDP..---.TALSELSKRQHPGKRYL....mLLHKRQH.PGRRELQEAD......................--..--.GH...SAELEKRQHPGKRRC-..------...----------.-.-----egwadagcgllelldts..................................................................................................................................................................................................................................................
A0A093Q948_9PASS/7-227               .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LWGV.CLNGRQPLPEESE.T.TRRS......PLDDI..LQRSES.LIFQSVLKK.AEKDEET.NKESKA..pL............SEWLSKRQHPGEKYLSK.LEKRQH.PGKR..D..V..EK......D........TSYGDIQKRQH.PGKRETEd.........................nLD.VYL.E.LK..KQQPP.GRRS....LL.DQ.IA.DSP.rAQL.TYMNELSKRQHPGRRYL.....-MYKHQQ.PSKRSWNY--......................EV..DL.ND...-QYGEKGQHPGKRHWN..SDSSDD...TGPCNFLEFF.T.CNKGS...................................................................................................................................................................................................................................................................
A0A3P8X2Y2_CYNSE/6-241               ........................................................................................................................................................................................................................................................................................LLLLASVW..FCHR.GHTVGQNLPSEDQ.T.ERR-......TIDEL.lLDRAES.LLLSSILQQ.VQDGDDR.DDGFSA..qP............QDWVTKRQHWGKRFDDG.LDKRQH.PGRR..E..E..DG......G........EQYLDLHRRQH.PGKRDDE...........................TH.SFL.E.LQ..KRQHP.GKRS....TS.TH.LH.EDP..--V.LVFAGLSKRQHPGKRYL....mLHSKRQH.PGRRLVEEGEgededg.........vwaaalgGS..QE.EL...EEELDKRQHPGKRFWD..NSSPDLd.tNSPCDVLDTT.G.CSRAN...................................................................................................................................................................................................................................................................
Q1T735_ORYLA/6-232                   ........................................................................................................................................................................................................................................................................................LLILASLA..ICNF.TVSDAQSISAEDE.T.DRTT......TTDDI.iLRRAES.LLLRSLLKK.MQDEDDI.NDGVYA...Q............QDWMAKRQHPGKRYRED.LEKRQH.PGRR..E..E..DE......D........EEYLNAQKRQH.PGKREDE...........................IQ.SSM.G.LQ..KRQHP.GKRF....LT.GH.IS.DNP..--I.IMLGELSKRQHPGKRYL....vLQSKRQH.PGKRYQDDEDsdg................dweAA..EE.VD...LPELEKRQHPGKRFWD..NSNPEL...GNPCDALEPD.N.CSKTN...................................................................................................................................................................................................................................................................
A0A091IU67_EGRGA/7-227               .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LSAL.CLNGGQPLPEGSE.N.MGRS......PLDDV..LKRSES.LILQPVLQK.AEKEEEM.NKESNA..pL............PEWLSKRQHPGKKYLSD.LEKRQH.PGKR..N..T..EE......D........TSYGDVQKRQH.PGKREIEd.........................dLD.GYL.E.LK..KQQYP.GRRP....LL.DR.YA.EIP.sAQL.AYLNELSKRQHPGRRYL.....-MYKRQH.PSKRGWNG--......................EV..DL.ND...-QYGEKRQHPGKRHWN..SNSPDG...AGPCNFQESF.T.CNKGS...................................................................................................................................................................................................................................................................
A0A3Q0RJ44_AMPCI/6-224               ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.MVSGGQSISAEDE.T.DRR-......TIDDI.vLERAET.LLLRSILKK.LQDEDAR.NDGYHS...Q............PEWVTKRQHPGKRYSDD.LEKRQH.PGRR..E..E..DE......D........EQYFDVHKRQH.PGKREDE...........................TH.SLV.E.LQ..KRQHP.GKRS....TA.GH.SS.DNP..--I.LLLSELSKRQHPGKRYL....vLHSKRQH.PGKRLLED--......................-E..DE.ED...LAEMEKRQHPGKRFWD..NSSPDLg.tNSPCDVLDPA.S.CSKTS...................................................................................................................................................................................................................................................................
A0A1S3MD66_SALSA/6-221               ........................................................................................................................................................................................................................................................................................LIILASLA..VCNL.TVARGQSIPAEEK.T.GDR-......QIDDI.iLQRAES.ILLRSILKM.T--EDGV.NEALSS...Q............PEWLVKRQHPGKGYQEE.LEKRQH.PGKR..E..E..DE......D........EDSREVQKRQH.PGKREDE...........................ID.SFV.E.LQ..KRQHP.GKRS....ML.EQ.IT.ENS..---.AFLSELSKRQHPGKRYL....mRYSKRQH.PGRRDVDD--......................ES..DA.GD...LQELEKRQHPGKRYWD..NMSPDLg.aNSPCDVLDP-.G.CSKAN...................................................................................................................................................................................................................................................................
U3CCY5_CALJA/6-207                   ........................................................................................................................................................................................................................................................................................LLLALALT..LNLI.GVPGGRAQPEAAQ.Q.EAVTaa.erpGLNDL..LRQAERlLFLRENILR.LQGDQGE.HSASQI..lQ............PDWLSKRQHPGKR-EEE.EEV---.-GVE..E.eE..EE......E........EGAVGPHKRQH.PGRREDEa.........................sWS.VDA.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVTRRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.KE...ELMPEKRQHPGKRAV-..------...GSSCEPQGA-.-.CG---qav................................................................................................................................................................................................................................................................
K7E2N6_MONDO/150-189                 .....................................................................................................................................................................................................................................................................................vkd--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.-S...EEDVSKRQHPGKRNLD..LDSQGS...AFPCSPRESS.H.CS---l..................................................................................................................................................................................................................................................................
A0A3B4B595_9GOBI/6-220               ........................................................................................................................................................................................................................................................................................LLVLASLA..VCNL.PHCKCQSLTEDDP.D.HR--......TIDDI.iLQKAES.LLLRSILKN.IQGDDER.YGGYTG..pP............SGWVTKRQHPGKRYTEE.------.----..D..T..DV......D........AQYLDVNKRQH.PGKREEE...........................MH.SYL.E.PQ..KRQHP.GKRT....AA.GF.VS.DNP..--L.LVLSELSKRQHPGKRYL....mLHTKRQH.PGKRFFPDADs...................dfDS..EG.EE...LAELEKRQHPGKRFLD..NSNPFLg.sNPPCDFLDSN.G.CSS--pq.................................................................................................................................................................................................................................................................
A0A3Q4HTY2_NEOBR/6-212               ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.MVSGGQSMSAEDE.T.DRK-......TIDDI.iLERAET.LLLRSILKK.LQDEDGR.NDGYYS...Q............PEWVTKRQHPGKRYKED.------.----..-..-..-E......D........EQYFDVQKRQH.PGKREDE...........................TH.SFL.E.LQ..KRQHP.GKRS....TA.GH.SS.DNP..--I.LLLSELSKRQHPGKRYL....vLHSKRQH.PGNDG--DAD......................AD..GE.ED...LAEMEKRQHPGKRFWD..NSSPDLg.tNSPCDVLDPA.S.CSKTS...................................................................................................................................................................................................................................................................
A0A3Q0CLB9_MESAU/6-211               ....................................................................................................................................................................................................................................................lllplaliftltgipefcalpvadqeegvvqmlper--------..----.-------------.-.----......-----..------.RFLQKDLQR.VRGDLGA.-----A...L............DSWITKRQHPGKREEEEeIEA-EE.G--G..D..L..GE......-........EGAWSPHKRQH.PGRRANQdkyswveaedsn...wvpttrlpgfflES.WYL.D.QV..KRQHP.GRRS....--.--.--.-FP..-W-.-MESDVTKRQHPGRRFI.....-----DP.KFQRSWEE--......................KE..EG.EG...IPMPEKRQHPGKRAL-..------...GQPCGPQGT-.-.CGQT-d..................................................................................................................................................................................................................................................................
A0A3B1JZN7_ASTMX/82-206              ........................................................................................................................................................................................................................................................................................--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-------KRQH.PGRREEEee.......................eeDG.DYP.E.LQ..KRQHP.GKRW....ML.EQ.MM.ETP.gAQN.ALLNELAKRQHPGKLLV.....LYSKRQH.PGRREAGA-E......................EP..DS.GD...LWEMDKRQHPGKRFWD..ASPSDAs.aGTPCDLLASSpG.CSKA-g..................................................................................................................................................................................................................................................................
G1SQS8_RABIT/7-210                   ........................................................................................................................................................................................................................................................................................LLLALAWT..LTLTgGVPGGRAQPESVH.Q.EGATap.erpGLEEL..LRQAERlLLLREDLQR.LRGDQGE.LPESQI..lQ............LDRLPKRQHPGKR-EEE.AEE---.-GVE..E..E..EE.....eE........GGAAGPHKRQH.PGRREDEa.........................sWA.ADG.T.QH..KWQHP.GPRS....--.--.--.--P..-WL.EY--AATKRQHPGRRMV.....-----DP.KVPRSWEEEEe....................eEE..EG.EG...ALMPEKRQHPGKRAL-..------...GGPCGPRGA-.-.CGE--ag.................................................................................................................................................................................................................................................................
H2QNC9_PANTR/6-205                   ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTav.ehpGLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..fQ............SDWLSKRQHPGKR-EEE.EEE---.-GVE..E..E..EE......-........GGAGGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.AY--AVPKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...DLMAEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
B5XBV3_SALSA/6-224                   ........................................................................................................................................................................................................................................................................................LIILASLV..VCNL.TLARGQGIPAEEE.T.GDRQ......TIDDI.iLQRAES.LLLRSILKN.IEDEDGA.NEGLTS...Q............PEWLVKRQHPGKRYQEE.LEKRQH.PGKR..E..E..DE......D........EDYGVVQKRQH.PGKREDE...........................FD.SFV.E.LQ..RRQHP.GKRL....ML.EQ.IT.ENP..---.AFLSELSKRQHPGKRYM....mYYSKRQH.PGRREVDE--......................ES..DA.GD...LKELEKRQHPGKRYLD..NTSPDLg.aNSPCDVLDP-.G.CSKAN...................................................................................................................................................................................................................................................................
A0A0A0ACE4_CHAVO/7-227               .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LCSV.CLNGGQPLPEGNE.N.LGRS......PLDDI..LQRSES.LILQSVLNK.AEKEEEM.NKESNA..pL............PEWLSKRQHPGKKYLND.MEKRQH.PGKR..Y..V..EE......D........TSYGDIQKRQH.PGKREIEd.........................dFD.GYL.E.LK..KRQHP.GRRS....LS.DQ.YA.DIP.gAQL.TYLNELSKRQHPGRRYL.....-MYKRQH.PSKRGWND--......................EA..DL.ND...-QYGEKRQQPGKRHWS..SDSPDD...AGPCNFHESF.T.CNKGS...................................................................................................................................................................................................................................................................
A0A2R9C4N0_PANPA/6-205               ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.ehpGLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..fQ............SDWLSKRQHPGKR-EEE.EEE---.-GVE..E..E..EE......-........GGAGGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.AY--AVPKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...DLIPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
A0A3P9PMS3_POERE/6-234               ........................................................................................................................................................................................................................................................................................LLVLASFV..ICNL.AVCDGQGLPAEDE.M.DRST......TIDNL.mLQRAQS.LLLRSILKK.LQDGDGR.NDGILS...Q............PQWVTKRQHPGKRYFED.LEKRQH.PGRR..E..V..VD......D........EQFWDMQKRQH.PGKREDE...........................MH.LFT.E.FQ..KRQHP.GKRS....TT.GH.IP.DSP..--V.ELLSELSKRQHPGKRYL....vLHSKRQH.PGKRLLEDEDgea................dwtED..GE.ED...MSELEKRQHPGKRFWD..NSSPELs.tSSPCDVLDSE.S.CSKTS...................................................................................................................................................................................................................................................................
A0A3B5ACP0_9TELE/6-235               ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.TVSGGQGIPAEDE.T.DPR-......TIDDI.iLQRAEN.LLLRSILKK.LQEEDGR.NEGFSS...L............PEWVTKRQHPGKRYSED.LEKRQH.PGRR..E..E..DE......D........EQYLDVQKRQH.PGKREDE...........................MH.SFM.E.LQ..KRQHP.GKRT....TV.GH.IS.DNP..--V.MLLSELSKRQHPGKRYL....vLHSKRQH.PGKRHPEDEDgdgd..............wdadAD..GE.ED...LSELEKRQHPGKRFWD..NSSPDLg.tNSPCDGLDPA.S.CSKTS...................................................................................................................................................................................................................................................................
A0A3L8RWD3_CHLGU/7-224               .......................................................................................................................................................................................................................................................................................p-LLLLCLS..SCGV.CFNGGHLLPEESE.N.MGKI......PLDDI..LQRSES.LILQSVLKK.AEKEEEI.NKELNA..pL............LQRLSKRQHPGKKYLNN.LEKRQH.PGKR..Y..V..EE......E........TSYGDIQKRQH.PGKREMEe.........................dFD.VYL.E.LK..RQQPP.GRKS....LL.DQ.FA.YSP.rAQL.AYMNELSKREHLGRRYL.....-MFKHQH.PSKRGWNY--......................EV..DV.YG...----EKRQHSGKRHWN..FDRSDD...TGPCNFQESF.T.CHKGS...................................................................................................................................................................................................................................................................
TRH_HUMAN/6-206                      ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.ehpGLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..fQ............SDWLSKRQHPGKREEEE.EEG---.-VEE..E..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.AY--AVPKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...DLMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.-----ygqa...............................................................................................................................................................................................................................................................
A0A402EFZ5_9SAUR/97-318              ........................................................................................................................................................................................................................................................................................FLLLFFLA..FTSV.CVNLGQPFPEDDN.E.ERG-......HLDDI..FQRAEN.IILRSILMK.PEDDEEDtNKDTSA..sQ............LNWISKRQHPGKRSLND.VDKRQH.PGKR..E..D..TS......D........GSYGETLKRQH.PGKREEDg.........................eFE.RYL.E.LQ..KRQHP.GRRA....LW.DL.YP.EIP.sNQL.AYPNEFSKRQHPGKRYL.....AYSKRQH.PGKRSWED--......................EL..DG.SE...-QDLEKRQHPGKRYLG..PESPDY...AVPCDPQESI.D.CSKGS...................................................................................................................................................................................................................................................................
A0A3Q7X3N9_URSAR/6-207               ........................................................................................................................................................................................................................................................................................LLLAMALT..LTVA.GIPGGRAQPEVAQ.Q.EAAMap.ehaGPDDL..LRQAQRlLFLREDLQR.LRGNQGD.LESEAQi.lQ............TNWLSKRQHPGKR-EGE.AEE---.-GVE..E..E..EE......E........GGAVGPHKRQH.PGRREDV..........................aAW.SDV.T.LQ..KRQHP.GRRS....--.--.--.--P..-LL.GY--TFTKRQHPGRRLV.....-----DS.KAQRSWEAEEe....................dEE..EE.GG...EPMPEKRQHPGKRAL-..------...GSPCGPGAA-.-.CGQAS...................................................................................................................................................................................................................................................................
TRH_MOUSE/6-125                      .......................................................................................................................................................................................................................................................................................l-MMALALI..FVLT.GIPKSCALLEAAQ.E.EGAVtp.dlpGLEKV..QVRPER.RFLRKDLQR.VRGDLGA.A-----...L............DSWITKRQHPGKRE--E.KEEDVE.AEER..G..D..LG......E........VGAWRPHKRQH.PGRRANQ...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----dkdswsde...........................................................................................................................................................................................................................................................
L9JDC1_TUPCH/6-134                   ....................................................................................................................................................................................................................................................................................llla--LAFALT..LTLT.HIPGGRAQPEAAQ.Q.EEAMagadrpGLDDL..LRQAERlLFLREDLQR.LQGNPGE.SPESPN..lQ............PDWLSKRQHPGKREEEE.EEG---.-AEE..E..E..EE......D........RGAVAPHKRQH.PGRREE-...........................--.---.-.--..-----.----....--.--.--.---..---.-----------------.....-------.----------......................--..--.--...----------------..------...----------.-.-----gappdrrwle.........................................................................................................................................................................................................................................................
A0A3Q3MEZ9_9TELE/6-232               ........................................................................................................................................................................................................................................................................................LLILASLA..LCNL.--SGGQGISAEDE.A.DRR-......TLDDI.iLQRAES.LLLRSILEK.MRDEDRR.NGEYDS...Q............PEWVTKRQHPGKRYSED.LEKRQH.PGRR..E..E..DE......D........DQYLNLQKRQH.PGKREGE...........................IH.SFS.E.LQ..KRQHP.GKRA....TL.GH.IS.DNP..---.LLLSELSKRQHPGKRYL....vLHNKRQH.PGKRYSEDVDgdad..............wdvdTD..GD.ED...LSEMEKRQHPGKRFWD..NSSPDLg.tNSPCDVLDTA.S.CSKTS...................................................................................................................................................................................................................................................................
G3NEZ6_GASAC/6-231                   ........................................................................................................................................................................................................................................................................................LLALALLV..VCNF.TVSGGQSIPAEDE.T.GGR-......TIDDI.iLQRAES.LLLRSILKK.IQDEDGG.DEGFPP...Q............AEWMTKRQHPGKRYGED.LEKRQH.PGRR..E..A..DV......D........EPYLDVQRRQH.PGKREDE...........................MR.PFT.E.LQ..KRQNP.GKRF....AA.GR.VS.ENP..--A.VL--ELSKRQHPGKRYL....vVQTKRQH.PGKRDGDDDVdwd................adgEG..GE.ED...LVEMEKRQHPGKRFWD..TSSPDLg.tNSPCDVLDPT.S.CRKTS...................................................................................................................................................................................................................................................................
A0A1S3ENE1_DIPOR/99-190              ...............................................................................................................................................................................................................................................................................aeeeaeggp--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................--.--V.A.PH..KRQHP.GRRS....--.--.--.--P..-WL.SY--AVTKRQHPGRRLA.....--DPKDP.KGQRSWEEEE......................EEggDG.EG...ALVPEKRQHPGKRAL-..------...EGPCGPPGA-.-.C----rpag...............................................................................................................................................................................................................................................................
A0A210R0X1_MIZYE/18-557              wqtpgkelldifvcrqtpgkellnmcmcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvc--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................--.---.-.--..-----.----....--.--.--.---..---.--------R--------.....-------.----------......................--..--.--...----------------..------...----------.-.-----qtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkelldifvcrqtpgkellnmcmcrqtpgkelldiflcretsdkkt
A0A3B3BSR8_ORYME/57-283              .......................................................................................................................................................................................................................................................................................l-FILASLA..ICNF.TVSEAQSISAEDE.T.DRTT......TIDDM.iLRRAES.LLLRSLLKK.MQDEDDT.NDGVFS...Q............QDWIAKRQHPGKRYRED.LEKRQH.PCKR..E..E..DE......D........EQFLDVQKRQH.PGKREDE...........................IH.SIM.G.LQ..KRQHP.GKRF....LA.GH.IS.DNP..--I.ILLSELSKRQHPGKRYL....vLHSKRQH.PGKRYQDDEDsdg................dweTT..EE.ED...LPELEKRQHPGKRLWD..NSNPEM...GNPCDALEPG.N.CSKTN...................................................................................................................................................................................................................................................................
A0A2D0QYL3_ICTPU/3-212               ....................................................................................................................................................................................................................................................................................avcl-LVLVSLA..---V.FSIQCQNVPSDSG.G.E-NP......TLDEV..LQRAEG.QLLRSFLQN.QQDNESS.NDLFPV...P............PDWLVKRQHPGKR----.----QH.PGKR..D..E..DDdd..deE........EEYAELQKRQH.PGKREDA...........................SD.LFV.A.LQ..RRQHP.GRRS....EL.EG.QT.--S..VQS.DLLSEFSKRQHPGKRYD.....AYDKRQH.PGRRDAEE-G......................AA..SS.VD...LWELDKRQHPGKRSWD..PSEVSS...GSPCDVPG--.-.CSK--as.................................................................................................................................................................................................................................................................
A0A2K5HPM3_COLAP/6-207               ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.erpGLDDL..LHQVERvLFLRENIQR.LQGDQGE.HSASQI..lQ............SDWLSKRQHPGKREEEE.EEG---.-VEE..E..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................sRS.VDV.T.QH..KRQHP.GRRS....--.--.--.--P..-WL.GY--AVAKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...ELMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
G1QZG4_NOMLE/6-207                   ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEVAQ.Q.EAVTaa.erpGLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..lQ............SDWLSKRQHPGKREEEE.EEG---.-VEE..E..E..EE......E........AGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QH..KRQHP.GWRS....--.--.--.--P..-WL.GY--AVLKRQHPGRRLA.....-----DP.KAQRSWEEEE.....................eEE..ER.EE...DLMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
A0A3Q2E740_CYPVA/6-234               .......................................................................................................................................................................................................................................................................................l-FVLASFL..ICNL.AVSEEQGLPAEDE.M.DRST......TIDNI.iLQRAQD.ILLRSILKK.LQNENDR.NDGIFS...Q............PEWMTKRQHPGKRYLED.LEKRQH.PGRR..E..G..GD......D........AQLWDVQKRQH.PGKREDE...........................VH.SFL.D.FQ..KRQHP.GKRS....TV.EY.IP.DNP..--T.ALLGELSKRQHPGKRYL....vLHSKRQH.PGKRFLEEEDgea................glfED..GE.ED...ASELEKRQHPGKRFWD..NSSPELs.tSNPCEVLDSD.S.CSKTS...................................................................................................................................................................................................................................................................
I3KKT6_ORENI/6-235                   ........................................................................................................................................................................................................................................................................................LLILASLT..VCNL.MVSGGQSMSAEDE.T.DRK-......TIDDI.iLERAET.LLLRSILKK.LQDEDGR.NDGYYS...Q............PEWVTKRQHPGKRYSDD.LEKRQH.PGRR..E..E..DE......D........EQYFDVQKRQH.PGKREDE...........................TH.SFL.E.PQ..KRQHP.GKRS....TA.GH.SS.DNP..--I.LLLSELSKRQHPGKRYL....vLHSKRQH.PGKRLLEDEDgdrd..............wdadAD..GE.ED...LAEMEKRQHPGKRFWD..NSSADLg.tNSPCDVLDPA.S.CSKTS...................................................................................................................................................................................................................................................................
H3AN56_LATCH/7-227                   ........................................................................................................................................................................................................................................................................................LLLLVSLG..LSSM.TAVLGQHAPEGVE.S.EESV......PMDDL..LQQAES.ILLRSILKK.MEEEKDL.HDPTAS...Q............VEWISKRQHPGKRFQAE.LEKRQH.PGKR..D..E..DE......E........IAYIEAQKRQH.PGKRGGE..........................gLD.EYT.E.VQ..KRQHP.GRRS....TL.DQ.FT.DSP.nTQL.AFLSELSKRQHPGKRYL.....LYNKRQH.PGKRGWDK--......................EL..DY.ED...LQELEKRQHPGKRQLP..PESPDY...GLPCDILDPI.N.CSKTS...................................................................................................................................................................................................................................................................
A0A1U7RQM3_ALLSI/6-227               ........................................................................................................................................................................................................................................................................................LLLLLSLT..LSGI.CLNLGQPTLDGGE.N.GERS......HLDDI..LQRAES.ILLRSILKK.VEEEEEL.NKEPDA..sE............PDSLSKRQHPGKRFFNE.LEKRQH.PGKR..E..D..GE......E........ALYGDIQKRQH.PGKREEDd.........................dLD.HYL.E.LQ..KRQHP.GKRS....LW.DQ.YV.DAP.gTQL.TYLNELSKRQHPGKRYL.....VYAKRQH.PGKRGWED--......................EL..DL.GE...-QDLEKRQHPGKRFSD..SESPDY...AAPCDLQDDF.N.CSKGS...................................................................................................................................................................................................................................................................
A0A226PNL5_COLVI/13-244              .......................................................................................................................................................................................................................................................................................p-VLLLCLT..LSGV.CLNGRQSPPEASE.N.MRS-......SLDDI..SQRSGS.HMLQSVLKK.VEKKEEM.NKGIYStgdNplyillyslaeiIRWLYKRQHPGKRYVSD.LEKRQH.PGKR..D..A..EE......E........TSYADIQKIQH.LGKTEDY...........................LA.NYP.E.LK..KRQHP.GRRS....LW.DQ.ST.GIP.sSQL.TYLNELSKTQHAGRRYL.....-MYKHQH.PSKRGWND--......................EL..DL.SG...-QNWEKHQHSRKRHRD..SGSLDY...AGPCDLQQSA.I.CNKSS...................................................................................................................................................................................................................................................................
G5C711_HETGA/112-178                 .....................................................................................................................................................................................................................................................................................rsp--------..----.-------------.-.----......-----..------.---------.-------.------...-............-----------------.------.----..-..-..--......-........-----------.-------...........................--.---.-.--..-----.----....--.--.--.---..-WL.EY--VVTKRQHPGRRLV.....-----DL.RSQRSWQEED.....................vEE..DR.EG...-PIPKKRQHPGKRAP-..------...GEPCGPQGA-.-.CDQAS...................................................................................................................................................................................................................................................................
R0K990_ANAPL/7-227                   .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LSGV.CLNGGQPLPEASE.N.MGRR......PLDNI..LQRSES.FILQSVLKK.AEKKEEM.NKELNA..pL............PEWLSKRQHPGKRYISD.LEKRQH.PGKR..D..V..KE......E........ASYGDIQKRQH.PGKREVEd.........................dLA.SYL.E.LK..KRQHP.GRRS....LW.DQ.HV.DIP.sARL.TYLNVLSKRQHPGRGYL.....-MHKHQH.PSKRGWND--......................EL..DI.SD...-HDGEKRQHPGKRHWD..TDNPDY...AGPCDLQESS.T.CNTGS...................................................................................................................................................................................................................................................................
A0A3B3SMM3_9TELE/5-216               ........................................................................................................................................................................................................................................................................................FLILLAFA..VCNL.NVNLCQNIPDEED.E.-G--......----A..LQRAET.LLLRSILKK.IEDDSSD.NEQVSS...L............QEWVSKRQHPGKRYEDD.LEKRQH.PGKR..E..E..EE......E........GDYSDLQKRQH.PGKREDE...........................--.--I.E.LE..RRQHP.GKRS....ML.ER.LT.DTY.gSPA.TYLNGFSKRQHPGKRYL.....VYNKRQH.PGRRELED--......................EV..NA.DD...QADLEKRQHPGKRFWD..NTSPDFg.aSDPCDTPDPA.KgCSKA-v..................................................................................................................................................................................................................................................................
TRH_CHICK/7-227                      .......................................................................................................................................................................................................................................................................................p-VLLLCLT..LSGV.CLNGRQFPPELSE.N.MGRS......SLDDI..LQRSGS.HMLQSVLKK.VEKKEEM.NKELNM..pL............PQWLSKRQHPGKRYISD.PEKRQH.PGKR..D..V..EE......K........ASFGDIQKRQH.LGKTEVEg.........................yLV.NYL.E.LK..KRQHP.GRRS....LW.DQ.ST.DIS.sSQL.TYLNELSKRQHPGRRYL.....-MYKHQH.PSKRGWND--......................EL..DL.SD...-QNWEKHQQFGNRDRD..SDSPDY...TGPCDLQQSA.I.CNKD-s..................................................................................................................................................................................................................................................................
A0A2I2YDN3_GORGO/6-207               ........................................................................................................................................................................................................................................................................................LLLALALT..LNLT.GVPGGRAQPEAAQ.Q.EAVTaa.ehpGLDDF..LRQVERlLFLRENIQR.LQGDQGE.HSASQI..fQ............SDWLSKRQHPGKREEKE.-EE---.-GVE.eE..E..EE......E........GGAVGPHKRQH.PGRREDEa.........................sWS.VDV.T.QY..KRQHP.GRRS....--.--.--.--P..-WL.AY--AVPKRQHPGRRLA.....-----DP.KSQRSWEEEE.....................eEE..ER.EE...DLMPEKRQHPGKRAL-..------...GGPCGPQGA-.-.CGQA-g..................................................................................................................................................................................................................................................................
M3WV29_FELCA/6-202                   ........................................................................................................................................................................................................................................................................................LLLALALT..LTVA.GIPGGRAQLEVAQ.H.EAGEh....aGLDDL..LRQAERlLLLQEDLLR.LRGNQDD.GESESQi.iQ............PDWLSKRQHPGKREEEE.AED---.-GVE..E..E..EE......-........GGAMGPHKRQH.PGRREDV..........................aAW.SEV.T.QQ..KRQHP.GRRS....--.--.--.---..SWL.GY--TFTKRQHPGRRLV.....-----DP.KAQRSWEEEE......................EE..VE.EG...ELMPEKRQHPGKRAL-..------...GGPCEPQGA-.-.CGQAS...................................................................................................................................................................................................................................................................
A0A087Y6U4_POEFO/6-234               ........................................................................................................................................................................................................................................................................................LLVLASFV..ICNL.AVCDGQGLPAEDE.M.DRST......TIDNL.mLQRAQS.LLLRSILKK.LQDGDGK.NDGILS...Q............PQWVTKRQHPGKRYFED.LEKRQH.PGRR..E..V..VD......D........EQFWDMQKRQH.PGKREDE...........................MH.SFT.E.FQ..KRQHP.GKRS....TT.GH.IP.DSP..--V.VVLSELSKRQHPGKRYL....vLHSKRQH.PGKRLFEDEDgea................dwtED..GE.ED...MTELEKRQHPGKRFWD..NSSPELs.tSSPCDVLDSD.S.CSKTS...................................................................................................................................................................................................................................................................
A0A091IDK5_CALAN/7-227               .......................................................................................................................................................................................................................................................................................p-LLLLCLT..LCGV.CLSGEQPLPEASE.N.MKRS......PLDDI..LQRSQS.LFLQSFLKK.AEKKEDI.NKESDA..pL............PEWLAKRQHPGRKFLSD.LEKRQH.PGKR..D..A..EE......E........KPYGDIHNWQH.PGKREIEd.........................dLN.SYL.E.LK..KRQHP.GRRS....VL.EQ.YA.DIS.sAQL.TYLNEISKRQHPGRRYL.....-MYKHQH.PRKRGWNV--......................EA..DL.ND...-QYGEEHQHAGKRDWN..SDSPDD...ASPCHFQDSS.T.SSKGS...................................................................................................................................................................................................................................................................
#=GC seq_cons                        .........................................................................................................................................................................................................................................................................................LlhhuLs..ls.h.slstGps.Pttsp.p.ttt.......slDDl..LppuEp.LlLRp.Lp+.hpt-ptt.ppt.tt...p............s-WloKRQHPGKR..p-.hEc.....Gcc..-..p..-E......-........tthhs.pKRQH.PG+RE--...........................hp.s.h.p..p..KRQHP.G+RS...............P....l.sh..ploKRQHPG+Rhl..........p...upRsh--........................-t..-t.ps.......EKRQHPGKRhh............suPCs..ss....Csps....................................................................................................................................................................................................................................................................
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