GenomeNet

Database: Pfam
Entry: TUDOR_5
LinkDB: TUDOR_5
Original site: TUDOR_5 
#=GF ID   TUDOR_5
#=GF AC   PF18359.1
#=GF DE   Histone methyltransferase Tudor domain 1
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF07256
#=GF GA   31.00 31.00;
#=GF TC   31.00 31.00;
#=GF NC   30.50 30.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   26296461
#=GF RT   Analysis of the subcellular localization of the human histone
#=GF RT   methyltransferase SETDB1.
#=GF RA   Tachibana K, Gotoh E, Kawamata N, Ishimoto K, Uchihara Y,
#=GF RA   Iwanari H, Sugiyama A, Kawamura T, Mochizuki Y, Tanaka T, Sakai
#=GF RA   J, Hamakubo T, Kodama T, Doi T;
#=GF RL   Biochem Biophys Res Commun. 2015;465:725-731.
#=GF RN   [2]
#=GF RM   27798683
#=GF RT   Ubiquitination of Lysine 867 of the Human SETDB1 Protein
#=GF RT   Upregulates Its Histone  H3 Lysine 9 (H3K9) Methyltransferase
#=GF RT   Activity.
#=GF RA   Ishimoto K, Kawamata N, Uchihara Y, Okubo M, Fujimoto R, Gotoh
#=GF RA   E, Kakinouchi K, Mizohata E, Hino N, Okada Y, Mochizuki Y,
#=GF RA   Tanaka T, Hamakubo T, Sakai J, Kodama T, Inoue T, Tachibana K,
#=GF RA   Doi T;
#=GF RL   PLoS One. 2016;11:e0165766.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the first TUDOR domain found in SETDB1 enzymes
#=GF CC   (EC:2.1.1.43) in homosapiens, also known as Eggless in
#=GF CC   Drosophila [1]. In Drosophila, SetdB1 (Egg) is important for
#=GF CC   oogenesis and the silencing of chromosome 4 [2]. SET domain,
#=GF CC   bifurcated 1 (SETDB1) is a histone methyltransferase (HMT) that
#=GF CC   methylates lysine 9 on histone H3 (H3K9). The enzymatic activity
#=GF CC   of SETDB1, in association with MBD1-containing
#=GF CC   chromatin-associated factor 1 (MCAF1), converts H3K9me2 to
#=GF CC   H3K9me3 and represses subsequent transcription. SETDB1 is
#=GF CC   amplified in cancers such as melanoma and lung cancer, and
#=GF CC   increased expression of SETDB1 promotes tumorigenesis in a
#=GF CC   zebrafish melanoma model. In addition, SETDB1 is required for
#=GF CC   endogenous retrovirus silencing during early embryogenesis,
#=GF CC   inhibition of adipocyte differentiation, and differentiation of
#=GF CC   mesenchymal cells into osteoblasts [1]. The tandem Tudor domains
#=GF CC   in the N-terminal region are involved in protein-protein
#=GF CC   interactions [2]. The second tudor domain is Pfam:PF18385.
#=GF SQ   280
#=GS A0A0D9RZL2_CHLSB/105-156    AC A0A0D9RZL2.1
#=GS H2N5X9_PONAB/258-309        AC H2N5X9.1
#=GS F7E6H0_MACMU/258-309        AC F7E6H0.2
#=GS G4VJ00_SCHMA/150-202        AC G4VJ00.1
#=GS A0A1I8IDI7_9PLAT/395-459    AC A0A1I8IDI7.1
#=GS A0A2I4D125_9TELE/490-538    AC A0A2I4D125.1
#=GS H2LBD0_ORYLA/212-260        AC H2LBD0.1
#=GS E9PRF4_HUMAN/258-309        AC E9PRF4.1
#=GS A0A158NJG1_ATTCE/346-397    AC A0A158NJG1.1
#=GS D3YYC3_MOUSE/258-309        AC D3YYC3.1
#=GS A0A1V4KMR9_PATFA/305-356    AC A0A1V4KMR9.1
#=GS E0VSB9_PEDHC/314-368        AC E0VSB9.1
#=GS A0A226F5M3_FOLCA/587-644    AC A0A226F5M3.1
#=GS A0A1S3A9P0_ERIEU/258-309    AC A0A1S3A9P0.1
#=GS J9NWE7_CANLF/76-127         AC J9NWE7.1
#=GS A0A194PSL4_PAPXU/1128-1177  AC A0A194PSL4.1
#=GS A0A212FGN1_DANPL/1562-1614  AC A0A212FGN1.1
#=GS F6XVT3_XENTR/260-311        AC F6XVT3.1
#=GS A0A1I8JI82_9PLAT/391-455    AC A0A1I8JI82.1
#=GS A0A084W5Y3_ANOSI/410-469    AC A0A084W5Y3.1
#=GS A0A2A4JI38_HELVI/252-304    AC A0A2A4JI38.1
#=GS A0A2G8KGE8_STIJA/166-218    AC A0A2G8KGE8.1
#=GS A7SYL7_NEMVE/100-150        AC A7SYL7.1
#=GS A0A1S3KCV2_LINUN/266-320    AC A0A1S3KCV2.1
#=GS A0A091CMK2_FUKDA/299-350    AC A0A091CMK2.1
#=GS A0A287BKD2_PIG/105-156      AC A0A287BKD2.1
#=GS A0A1U8DYJ4_ALLSI/264-315    AC A0A1U8DYJ4.1
#=GS A0A218UE46_9PASE/264-315    AC A0A218UE46.1
#=GS F6YYF6_HORSE/258-309        AC F6YYF6.1
#=GS A0A0R3U4N4_9CEST/271-323    AC A0A0R3U4N4.1
#=GS T0RJS0_9STRA/166-212        AC T0RJS0.1
#=GS F6YYP8_MONDO/395-446        AC F6YYP8.2
#=GS A0A067QY42_ZOONE/35-88      AC A0A067QY42.1
#=GS A0A226MKM5_CALSU/332-383    AC A0A226MKM5.1
#=GS A0A162QA47_9CRUS/334-390    AC A0A162QA47.1
#=GS E9HTR0_DAPPU/338-394        AC E9HTR0.1
#=GS A0A1S3IVM9_LINUN/266-320    AC A0A1S3IVM9.1
#=GS G4VJ01_SCHMA/264-316        AC G4VJ01.1
#=GS F7B9J0_CALJA/258-309        AC F7B9J0.1
#=GS A0A1A9XPS9_GLOFF/642-704    AC A0A1A9XPS9.1
#=GS W5JEX8_ANODA/482-539        AC W5JEX8.1
#=GS D4A081_RAT/258-309          AC D4A081.1
#=GS A0A087XFB0_POEFO/290-341    AC A0A087XFB0.2
#=GS A0A1B0BRM8_9MUSC/642-704    AC A0A1B0BRM8.1
#=GS B4J4D7_DROGR/651-712        AC B4J4D7.1
#=GS A0A096LRY5_POEFO/278-329    AC A0A096LRY5.1
#=GS A0A2C9KBL5_BIOGL/70-122     AC A0A2C9KBL5.1
#=GS A0A1I7SU76_BURXY/367-418    AC A0A1I7SU76.1
#=GS A0A0R4IPA3_DANRE/277-328    AC A0A0R4IPA3.1
#=GS A0A0M5J2T6_DROBS/437-496    AC A0A0M5J2T6.1
#=GS E9J254_SOLIN/333-384        AC E9J254.1
#=GS M7B6Z7_CHEMY/170-221        AC M7B6Z7.1
#=GS A0A087XFK2_POEFO/263-314    AC A0A087XFK2.1
#=GS G3WHI0_SARHA/258-309        AC G3WHI0.1
#=GS A0A1I8HR48_9PLAT/339-391    AC A0A1I8HR48.1
#=GS A0A151M5E2_ALLMI/328-379    AC A0A151M5E2.1
#=GS T0S9U5_9STRA/58-104         AC T0S9U5.1
#=GS J9KGN5_ACYPI/280-334        AC J9KGN5.2
#=GS SETB1_HUMAN/258-309         AC Q15047.1
#=GS SETB1_HUMAN/258-309         DR PDB; 5KH6 A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6BPI A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6AU3 A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 5KCO A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 3DLM A; 69-120;
#=GS SETB1_HUMAN/258-309         DR PDB; 5KE2 A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6BHI A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6BHE A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6BHD A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6BHH A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 5KE3 A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6AU2 A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 5KCH A; 258-309;
#=GS SETB1_HUMAN/258-309         DR PDB; 6BHG A; 258-309;
#=GS B4GIE1_DROPE/596-656        AC B4GIE1.1
#=GS G3RJM2_GORGO/258-309        AC G3RJM2.2
#=GS T0Q6A6_9STRA/354-399        AC T0Q6A6.1
#=GS A0A182VI58_ANOME/374-429    AC A0A182VI58.1
#=GS F0Y7E4_AURAN/94-137         AC F0Y7E4.1
#=GS A0A1B0DMP7_PHLPP/933-984    AC A0A1B0DMP7.1
#=GS A0A226NX34_COLVI/172-223    AC A0A226NX34.1
#=GS T1JZ06_TETUR/317-372        AC T1JZ06.1
#=GS A0A2I4AXH0_9TELE/277-328    AC A0A2I4AXH0.1
#=GS G3PCX5_GASAC/263-314        AC G3PCX5.1
#=GS A0A182RJ96_ANOFN/542-597    AC A0A182RJ96.1
#=GS SETB1_DROME/530-591         AC Q32KD2.1
#=GS A7SWQ8_NEMVE/108-157        AC A7SWQ8.1
#=GS A0A067BTL2_SAPPC/776-823    AC A0A067BTL2.1
#=GS B4LN52_DROVI/634-695        AC B4LN52.2
#=GS A0A182W7G5_9DIPT/379-433    AC A0A182W7G5.1
#=GS F1R772_DANRE/634-686        AC F1R772.2
#=GS A0A151JZN9_9HYME/336-387    AC A0A151JZN9.1
#=GS A0A182NTK7_9DIPT/485-536    AC A0A182NTK7.1
#=GS A0A1D2MCJ8_ORCCI/131-186    AC A0A1D2MCJ8.1
#=GS A0A182F1J2_ANOAL/493-550    AC A0A182F1J2.1
#=GS B0XAP5_CULQU/240-306        AC B0XAP5.1
#=GS A0A0L0CQA2_LUCCU/775-836    AC A0A0L0CQA2.1
#=GS M4AQ98_XIPMA/278-329        AC M4AQ98.1
#=GS A0A0F8AEB0_LARCR/276-327    AC A0A0F8AEB0.1
#=GS A0A1S3MUY0_SALSA/348-399    AC A0A1S3MUY0.1
#=GS G3H2X6_CRIGR/200-251        AC G3H2X6.1
#=GS A0A195DKZ4_9HYME/308-359    AC A0A195DKZ4.1
#=GS A0A1S3WLW4_ERIEU/258-309    AC A0A1S3WLW4.1
#=GS G3WHI1_SARHA/258-309        AC G3WHI1.1
#=GS STB1B_DANRE/267-318         AC Q08BR4.2
#=GS A0A182L1Y1_9DIPT/298-353    AC A0A182L1Y1.1
#=GS H3CRK5_TETNG/255-306        AC H3CRK5.1
#=GS I3JGZ5_ORENI/270-321        AC I3JGZ5.1
#=GS H2UKE0_TAKRU/263-314        AC H2UKE0.1
#=GS L5K5I1_PTEAL/258-309        AC L5K5I1.1
#=GS G1T430_RABIT/258-309        AC G1T430.2
#=GS STB1A_DANRE/634-686         AC Q1L8U8.1
#=GS A0A087XQP9_POEFO/213-261    AC A0A087XQP9.1
#=GS K7ILY5_NASVI/334-385        AC K7ILY5.1
#=GS A0A154PEE2_9HYME/1169-1220  AC A0A154PEE2.1
#=GS A0A087XQN8_POEFO/152-200    AC A0A087XQN8.1
#=GS F4WGP5_ACREC/336-387        AC F4WGP5.1
#=GS G5AJY0_HETGA/258-309        AC G5AJY0.1
#=GS A0A151IE23_9HYME/338-389    AC A0A151IE23.1
#=GS E1BKH5_BOVIN/263-314        AC E1BKH5.2
#=GS SETB1_DROPS/536-596         AC Q28Z18.2
#=GS A0A286ZY41_PIG/258-309      AC A0A286ZY41.1
#=GS L8Y8R6_TUPCH/258-309        AC L8Y8R6.1
#=GS H9GIB6_ANOCA/264-315        AC H9GIB6.1
#=GS A0A2D0R211_ICTPU/292-343    AC A0A2D0R211.1
#=GS A0A182ZZX8_9TREM/85-137     AC A0A182ZZX8.1
#=GS A0A158PJ89_ANGCS/274-327    AC A0A158PJ89.1
#=GS A0A182U139_9DIPT/345-400    AC A0A182U139.1
#=GS A0A2I3TGZ2_PANTR/258-309    AC A0A2I3TGZ2.1
#=GS T0Q6A6_9STRA/287-333        AC T0Q6A6.1
#=GS A0A1I8H7U6_9PLAT/287-339    AC A0A1I8H7U6.1
#=GS A0A074ZL29_9TREM/261-296    AC A0A074ZL29.1
#=GS E9HRD0_DAPPU/291-347        AC E9HRD0.1
#=GS A0A183BVS5_GLOPA/312-369    AC A0A183BVS5.1
#=GS A0A1L8FBV0_XENLA/326-377    AC A0A1L8FBV0.1
#=GS A0A096MVU1_PAPAN/258-309    AC A0A096MVU1.2
#=GS A0A182GTC3_AEDAL/1123-1186  AC A0A182GTC3.1
#=GS A0A183KQK4_9TREM/28-75      AC A0A183KQK4.1
#=GS E2ATZ3_CAMFO/267-318        AC E2ATZ3.1
#=GS A0A182PZR8_9DIPT/347-397    AC A0A182PZR8.1
#=GS A0A182M0Q0_9DIPT/464-518    AC A0A182M0Q0.1
#=GS A0A1U8DNI1_ALLSI/264-315    AC A0A1U8DNI1.1
#=GS A0A2D0S206_ICTPU/498-549    AC A0A2D0S206.1
#=GS A0A0L7QQN1_9HYME/333-384    AC A0A0L7QQN1.1
#=GS A0A096LWV0_POEFO/294-345    AC A0A096LWV0.1
#=GS M3WBU8_FELCA/258-309        AC M3WBU8.2
#=GS A0A1A6HLN9_NEOLE/140-191    AC A0A1A6HLN9.1
#=GS A0A1I8BD64_MELHA/382-439    AC A0A1I8BD64.1
#=GS A0A0N0PDV3_PAPMA/1083-1132  AC A0A0N0PDV3.1
#=GS M3XYW3_MUSPF/263-314        AC M3XYW3.1
#=GS H0UWN1_CAVPO/258-309        AC H0UWN1.2
#=GS J9P7P5_CANLF/258-309        AC J9P7P5.1
#=GS X1WR37_ACYPI/260-314        AC X1WR37.1
#=GS H0Z2Q1_TAEGU/185-236        AC H0Z2Q1.1
#=GS T1IYR1_STRMM/200-254        AC T1IYR1.1
#=GS V9DXY3_PHYPR/36-80          AC V9DXY3.1
#=GS B7PPM4_IXOSC/278-332        AC B7PPM4.1
#=GS A0A182G2F1_AEDAL/1126-1189  AC A0A182G2F1.1
#=GS A0A2D0S1X9_ICTPU/499-550    AC A0A2D0S1X9.1
#=GS A0A1S3PXQ1_SALSA/395-446    AC A0A1S3PXQ1.1
#=GS W4Z632_STRPU/31-85          AC W4Z632.1
#=GS B3SBL7_TRIAD/159-208        AC B3SBL7.1
#=GS H2M4D0_ORYLA/244-295        AC H2M4D0.1
#=GS G1RG51_NOMLE/258-309        AC G1RG51.2
#=GS A7SWQ8_NEMVE/372-422        AC A7SWQ8.1
#=GS A0A067BTL2_SAPPC/245-290    AC A0A067BTL2.1
#=GS A0A1I8P1Y1_STOCA/939-1000   AC A0A1I8P1Y1.1
#=GS B4IH79_DROSE/211-272        AC B4IH79.1
#=GS A0A067BTL2_SAPPC/137-182    AC A0A067BTL2.1
#=GS A0A0T6B9S1_9SCAR/480-541    AC A0A0T6B9S1.1
#=GS H0X2F3_OTOGA/259-310        AC H0X2F3.1
#=GS B3SBL5_TRIAD/207-272        AC B3SBL5.1
#=GS A0A0P7TYV5_9TELE/200-251    AC A0A0P7TYV5.1
#=GS H2UKE1_TAKRU/260-311        AC H2UKE1.1
#=GS H2UKD9_TAKRU/263-314        AC H2UKD9.1
#=GS A0A287BEQ3_PIG/258-309      AC A0A287BEQ3.1
#=GS C3Y5H5_BRAFL/366-420        AC C3Y5H5.1
#=GS G3STG1_LOXAF/258-309        AC G3STG1.1
#=GS H3ASP5_LATCH/251-302        AC H3ASP5.1
#=GS T1FPH6_HELRO/180-232        AC T1FPH6.1
#=GS I3M8I9_ICTTR/258-309        AC I3M8I9.2
#=GS A0A0R3W9Y8_TAEAS/270-322    AC A0A0R3W9Y8.2
#=GS B4KTI6_DROMO/621-682        AC B4KTI6.2
#=GS B7P544_IXOSC/36-90          AC B7P544.1
#=GS A0A2K5P577_CERAT/243-294    AC A0A2K5P577.1
#=GS A0A182J3P8_9DIPT/446-508    AC A0A182J3P8.1
#=GS S7MVH5_MYOBR/274-325        AC S7MVH5.1
#=GS A0A1L8F4F5_XENLA/265-316    AC A0A1L8F4F5.1
#=GS A0A2I4AYF4_9TELE/271-321    AC A0A2I4AYF4.1
#=GS K1R5K2_CRAGI/527-579        AC K1R5K2.1
#=GS B2GRL9_DANRE/267-318        AC B2GRL9.1
#=GS F7A203_CALJA/263-314        AC F7A203.1
#=GS A0A067BTL2_SAPPC/564-610    AC A0A067BTL2.1
#=GS A0A094ZXJ4_SCHHA/1-46       AC A0A094ZXJ4.1
#=GS A0A0C2MIC2_THEKT/1-50       AC A0A0C2MIC2.1
#=GS A0A1W4ULS7_DROFC/558-619    AC A0A1W4ULS7.1
#=GS A0A1D2MW35_ORCCI/388-445    AC A0A1D2MW35.1
#=GS A7SP53_NEMVE/1997-2048      AC A7SP53.1
#=GS J9K0P6_ACYPI/360-414        AC J9K0P6.2
#=GS W5L9Z5_ASTMX/251-302        AC W5L9Z5.1
#=GS W5QI91_SHEEP/263-314        AC W5QI91.1
#=GS A0A182JXT1_9DIPT/460-515    AC A0A182JXT1.1
#=GS F1SS95_PIG/258-309          AC F1SS95.2
#=GS G1L2Y3_AILME/263-314        AC G1L2Y3.1
#=GS Q17D97_AEDAE/75-138         AC Q17D97.1
#=GS A0A182XZV8_ANOST/514-569    AC A0A182XZV8.1
#=GS A0A1U7T5F2_TARSY/258-309    AC A0A1U7T5F2.1
#=GS Q7Q3P9_ANOGA/271-326        AC Q7Q3P9.4
#=GS A0A182HV29_ANOAR/527-582    AC A0A182HV29.1
#=GS A0A151M5C4_ALLMI/328-379    AC A0A151M5C4.1
#=GS G7YBR9_CLOSI/276-328        AC G7YBR9.1
#=GS A0A1S3CUX9_DIACI/366-414    AC A0A1S3CUX9.1
#=GS A0A1J1INV5_9DIPT/933-991    AC A0A1J1INV5.1
#=GS X1X4B9_ACYPI/284-323        AC X1X4B9.1
#=GS K7B3J1_PANTR/258-309        AC K7B3J1.1
#=GS A0A1I8I8L3_9PLAT/927-991    AC A0A1I8I8L3.1
#=GS A0A232F7G5_9HYME/782-833    AC A0A232F7G5.1
#=GS A7T0X8_NEMVE/351-401        AC A7T0X8.1
#=GS A0A1D2N373_ORCCI/234-291    AC A0A1D2N373.1
#=GS A0A183NAC3_9TREM/202-254    AC A0A183NAC3.1
#=GS A0A1B0AF68_GLOPL/643-705    AC A0A1B0AF68.1
#=GS G5E8N3_MOUSE/258-309        AC G5E8N3.1
#=GS H3GBS4_PHYRM/71-118         AC H3GBS4.1
#=GS A0A1I8JEB6_9PLAT/287-339    AC A0A1I8JEB6.1
#=GS A0A226F0L3_FOLCA/606-663    AC A0A226F0L3.1
#=GS A0A1W4XQY0_AGRPL/491-538    AC A0A1W4XQY0.1
#=GS A0A068XTU2_ECHMU/271-317    AC A0A068XTU2.1
#=GS A0A182WT32_ANOQN/517-572    AC A0A182WT32.1
#=GS A0A2D0R1U2_ICTPU/292-343    AC A0A2D0R1U2.1
#=GS A0A0R3TLV4_HYMNN/269-321    AC A0A0R3TLV4.1
#=GS A0A0G2K5A7_RAT/278-329      AC A0A0G2K5A7.1
#=GS A0A139WDT3_TRICA/396-456    AC A0A139WDT3.1
#=GS A0A093J165_EURHL/69-119     AC A0A093J165.1
#=GS T0R2Y4_9STRA/58-104         AC T0R2Y4.1
#=GS I3JGZ4_ORENI/276-327        AC I3JGZ4.1
#=GS J9JU99_ACYPI/276-330        AC J9JU99.1
#=GS D6WYT6_TRICA/154-214        AC D6WYT6.2
#=GS T1JK41_STRMM/78-129         AC T1JK41.1
#=GS A0A0L8H098_OCTBM/1-46       AC A0A0L8H098.1
#=GS A0A2I3H4W3_NOMLE/258-309    AC A0A2I3H4W3.1
#=GS A0A164ZKP0_9CRUS/306-362    AC A0A164ZKP0.1
#=GS A0A2B4S578_STYPI/433-482    AC A0A2B4S578.1
#=GS A0A1D2ME92_ORCCI/369-426    AC A0A1D2ME92.1
#=GS A0A1U7QR72_MESAU/129-180    AC A0A1U7QR72.1
#=GS A0A1S3WLW5_ERIEU/71-122     AC A0A1S3WLW5.1
#=GS G7NTT5_MACFA/258-309        AC G7NTT5.1
#=GS A0A026W0J7_OOCBI/337-388    AC A0A026W0J7.1
#=GS A0A151WI55_9HYME/337-388    AC A0A151WI55.1
#=GS A0A1B0CWL2_LUTLO/1435-1486  AC A0A1B0CWL2.1
#=GS G3WHI2_SARHA/258-309        AC G3WHI2.1
#=GS H9L3I9_CHICK/390-441        AC H9L3I9.3
#=GS A0A1S3A9W0_ERIEU/258-309    AC A0A1S3A9W0.1
#=GS G5A2N1_PHYSP/72-113         AC G5A2N1.1
#=GS A0A0K0D2S9_ANGCA/407-460    AC A0A0K0D2S9.1
#=GS A0A158QFJ0_HYMDI/269-321    AC A0A158QFJ0.1
#=GS E2QW40_CANLF/261-312        AC E2QW40.2
#=GS L5MET7_MYODS/307-344        AC L5MET7.1
#=GS B3MC21_DROAN/538-599        AC B3MC21.2
#=GS A0A286ZV06_PIG/120-171      AC A0A286ZV06.1
#=GS A0A2D0R3I4_ICTPU/177-228    AC A0A2D0R3I4.1
#=GS A0A1A9X4V2_9MUSC/633-694    AC A0A1A9X4V2.1
#=GS A0A2D0S1X4_ICTPU/499-550    AC A0A2D0S1X4.1
#=GS SETB1_MOUSE/258-309         AC O88974.1
#=GS A0A1D2M340_ORCCI/138-191    AC A0A1D2M340.1
#=GS A0A0N0PDV3_PAPMA/1214-1261  AC A0A0N0PDV3.1
#=GS A0A1V9X194_9ACAR/377-426    AC A0A1V9X194.1
#=GS B4MP92_DROWI/111-175        AC B4MP92.1
#=GS A0A1U8DNH9_ALLSI/264-315    AC A0A1U8DNH9.1
#=GS W6UDU9_ECHGR/150-202        AC W6UDU9.1
#=GS A0A2K5JAN0_COLAP/243-294    AC A0A2K5JAN0.1
#=GS G1MQP3_MELGA/262-313        AC G1MQP3.2
#=GS A0A151HXM5_9HYME/336-387    AC A0A151HXM5.1
#=GS A0A2I3HIG4_NOMLE/258-309    AC A0A2I3HIG4.1
#=GS F0Y7E4_AURAN/217-262        AC F0Y7E4.1
#=GS A0A1S3F3U0_DIPOR/258-295    AC A0A1S3F3U0.1
#=GS A0A067BTL2_SAPPC/630-674    AC A0A067BTL2.1
#=GS A0A1I8MWS1_MUSDO/704-765    AC A0A1I8MWS1.1
#=GS G1PG25_MYOLU/265-316        AC G1PG25.1
#=GS U4U7K2_DENPD/298-358        AC U4U7K2.1
#=GS A0A068XA93_HYMMI/269-321    AC A0A068XA93.1
#=GS A0A087TZN4_9ARAC/85-147     AC A0A087TZN4.1
#=GS T0R2Y4_9STRA/117-163        AC T0R2Y4.1
#=GS A0A093RE21_PYGAD/194-245    AC A0A093RE21.1
#=GS A0A182PD15_9DIPT/352-407    AC A0A182PD15.1
#=GS H9G2L0_MACMU/258-309        AC H9G2L0.1
#=GS U3J2K8_ANAPL/252-303        AC U3J2K8.1
#=GS S9XWZ0_CAMFR/258-309        AC S9XWZ0.1
#=GS A0A0R3X6T6_HYDTA/271-317    AC A0A0R3X6T6.1
#=GS A0A2D0S2U9_ICTPU/499-550    AC A0A2D0S2U9.1
#=GS T0RJS0_9STRA/107-152        AC T0RJS0.1
#=GS T0Q6A6_9STRA/138-183        AC T0Q6A6.1
#=GS A7T4H9_NEMVE/317-368        AC A7T4H9.1
#=GS E9PQM8_HUMAN/258-309        AC E9PQM8.1
#=GS A0A088APQ1_APIME/334-384    AC A0A088APQ1.1
#=GS F0Y7E4_AURAN/803-848        AC F0Y7E4.1
A0A0D9RZL2_CHLSB/105-156               ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
H2N5X9_PONAB/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
F7E6H0_MACMU/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
G4VJ00_SCHMA/150-202                   ...YPVGARVVSI............Y..RDD..............TGGIGYYSGLIAEPPSERNNQ..RYLLFFDDGYTQYSP---pne.....
A0A1I8IDI7_9PLAT/395-459               ..c-PVGTRVVSTva.......dpdY..ADEgpd.......aeadGDETPRYAGIVAESPGEANKF..RYLIFFDDGYCQYSE---qaa.....
A0A2I4D125_9TELE/490-538               ...LFVGARVVVK............S..-ES..............-DQADFQPGILTEVPNRKNRM..RFLVFIDD----------htpvycpl
H2LBD0_ORYLA/212-260                   ...LCVGARVVVR............C..QNN..............--KFRFRPGILAELPSRKNQF..RFLVFVDDH---------tpvyvgl.
E9PRF4_HUMAN/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A158NJG1_ATTCE/346-397               ...IPVGTRVVAI............F..HDV..............-VSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
D3YYC3_MOUSE/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1V4KMR9_PATFA/305-356               ..h-YVGSRVVAK............Y..KDG..............-NQVWLYAGIVAEAPNVKNKD..RFLIFFDDGYASYVKE--we......
E0VSB9_PEDHC/314-368                   ...YPVGTRIVAL............F..HNSk............aPSKSAFYAGIIAEPPKILNMF..RYLVFFDDGYAQYVTHHK........
A0A226F5M3_FOLCA/587-644               ...LIVGTRVIAK............F..REDlk.........ekpHGPDGHYAGIVAEQPTPRNKF..RYLIFFDDGCAQYVGI--nd......
A0A1S3A9P0_ERIEU/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
J9NWE7_CANLF/76-127                    ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A194PSL4_PAPXU/1128-1177             ...LIIGTRIIAC............A..---..............EKTDSFYSGVVAEVPNPVNKF..RYLVFFDDGHAKYVQHAD........
A0A212FGN1_DANPL/1562-1614             lph---CTRVIAL............F..KDI..............MRREFFYPGIVAEMPNPRNSY..RYLIFFDDGYSQYAPHSK........
F6XVT3_XENTR/260-311                   ...LVVGSRVVAK............Y..KDG..............-NQVWLYAGIVAEPPSNKNKM..RYLIFFDDGYASYVTHA-e.......
A0A1I8JI82_9PLAT/391-455               ..c-PVGTRVVSTva.......dpdY..ADEgpd.......aeadGDETPRYAGIVAESPGEANKF..RYLIFFDDGYCQYSE---qaa.....
A0A084W5Y3_ANOSI/410-469               .ip--QGNRVIAK............T.aR-Reed.......ldveHDETAFYAGFVAESLHQYNSH..RYLIIFDNGRTCYAH---swn.....
A0A2A4JI38_HELVI/252-304               ...MTIGTRLIAL............F..KDS..............SKRESFYSGVVAEIPNPVNSY..RYLVFFDDGYAQYVQHQH........
A0A2G8KGE8_STIJA/166-218               ...LTIGQRVVAL............F..REE..............DGDDCLYAGVIAEMPMTTNHG..RYLVFFDDGYVQYMHRK-r.......
A7SYL7_NEMVE/100-150                   ...VPIGARVIAA............F..---..............EGRCHYYKGRVTQI-DLTNPYapRYHVTYDDGDKGWVNCDK........
A0A1S3KCV2_LINUN/266-320               ...LPVGTRVVAL............Y..KDEe............aTPSTSFYAGIVAEPPNVRNNN..RFLVFFDDGYAQYSQPKD........
A0A091CMK2_FUKDA/299-350               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A287BKD2_PIG/105-156                 ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKN..RFLIFFDDGYASYVTES-e.......
A0A1U8DYJ4_ALLSI/264-315               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQ--pe......
A0A218UE46_9PASE/264-315               ..h-HVGRRVVAK............Y..KDG..............-NQMWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVKE--we......
F6YYF6_HORSE/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A0R3U4N4_9CEST/271-323               ...YPVGARAVAL............Y..QDD..............NGGTAYYSGIIAEPPNERNSY..RYLIFFDDGYAYYAQPK-c.......
T0RJS0_9STRA/166-212                   ...LKVGTKVEAK............Y..---..............KGKAKFYPGKITKVHADG---..SYDIDYDDGEHEKRVES-d.......
F6YYP8_MONDO/395-446                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A067QY42_ZOONE/35-88                 ..f-PVGTRVIAV............F..QDN.............dWSKECYYSGVIAEPPKSMNKY..RYLVFFDDGYAQYVTHEK........
A0A226MKM5_CALSU/332-383               ..h-YVGSRVVAK............Y..KDG..............-DQVWLYAGIVAETPNMKNKD..RFLIFFDDGYASYVKE--we......
A0A162QA47_9CRUS/334-390               ...LTVGSRVIAQ............Y..VEDkd..........gkLKPSSYYAGVVAEAPKTLNQY..RYLIFFDDGYAQYCTHEQ........
E9HTR0_DAPPU/338-394                   ...LTVGARVIAQ............Y..VEDkd..........gkLKPSSYYAGVIAEAPKTLNQY..RYLVFFDDGYAQYCTHEQ........
A0A1S3IVM9_LINUN/266-320               ...LPVGTRVVAL............Y..KDEe............aTPSTSFYAGIVAEPPNVRNNN..RFLVFFDDGYAQYSQPKD........
G4VJ01_SCHMA/264-316                   ...YPVGARVVSI............Y..RDD..............TGGIGYYSGLIAEPPSERNNQ..RYLLFFDDGYTQYSP---pne.....
F7B9J0_CALJA/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1A9XPS9_GLOFF/642-704               ...LPTGARVIAY............F..DATsltrg....kekvtTVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
W5JEX8_ANODA/482-539                   ...LMLGTRVIAKi.........esY..--Vgk..........ggNVQDAFYPGVVGESLGSYNRY..RYLVFYDDGYAQYLPPKD........
D4A081_RAT/258-309                     ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A087XFB0_POEFO/290-341               ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
A0A1B0BRM8_9MUSC/642-704               ...LPTGARVIAY............F..DATsltrg....kekvtTVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
B4J4D7_DROGR/651-712                   ...LTIGTRVIAY............F..NGStlsr.....gkekcVVPSAFYPGIIAEPLKQANRF..RYLIFYDDGYTQYVQHSD........
A0A096LRY5_POEFO/278-329               ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
A0A2C9KBL5_BIOGL/70-122                ..i-KVGTRVVAV............Y..KEE..............DAANSFYAGVIAEAPSAKNNR..RFLVFFDDGYAQYCDAK-e.......
A0A1I7SU76_BURXY/367-418               .cn--AGTRVLAK............Y..KGI..............-DENKWKWGTLGTFPIKEYRF..HYLVFFDDGTVQFIRPK-n.......
A0A0R4IPA3_DANRE/277-328               ...LFVGARVVAR............Y..KDG..............-NQVWLYAGVVAEMPNSKNRM..RFLIFFDDGYASYVG---lpe.....
A0A0M5J2T6_DROBS/437-496               ..l-LLGTRVIAF............F..DGStls.......rgkaMVQSAFYPGIIAEPLKQANGF..RYLIFYDDGYTQYVQHND........
E9J254_SOLIN/333-384                   ...IPVGTRVVAI............F..RDT..............-CSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
M7B6Z7_CHEMY/170-221                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNMKNKL..RFLIFFDDGYASYVTQS-e.......
A0A087XFK2_POEFO/263-314               ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
G3WHI0_SARHA/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1I8HR48_9PLAT/339-391               ...YPVGARVVSS............Y..TDD..............RGLVFYYSAIVAEPPGERNSR..RYLLFFDDGYAQYAPPSD........
A0A151M5E2_ALLMI/328-379               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQ--pe......
T0S9U5_9STRA/58-104                    ..w-TVGSRVLAR............Y..---..............NGDDDFYAGTITAVDDEN--R..VYDIAYDDGEVE------envsy...
J9KGN5_ACYPI/280-334                   ...YPVGSRVIAK............F..QDVd............iKLTDKFYVGIIAEPPKLLNNF..RYMIFFDDGYVQYVCHK-n.......
SETB1_HUMAN/258-309                    ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
#=GR SETB1_HUMAN/258-309         SS    ...--TT-EEEEE............E..EET..............-TEEEEEEEEEEE-S-TTTTS..-EEEEETTS-EEEE-GG-G.......
B4GIE1_DROPE/596-656                   ...LPIGTRVIAF............F..DGTlvgg......kekgVVQSAFYPGIIAEPLKQNNRF..RYLIFYDDGYTQYVHHSD........
G3RJM2_GORGO/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
T0Q6A6_9STRA/354-399                   ...LVVGTKVEAK............Y..---..............-KGKTYYPGTIAKVNDDE---..SYDIDYDDGEKEKR----vdrd....
A0A182VI58_ANOME/374-429               ..l-LLGTRVVAR............T..-SSpt..........qdGMNRTFYAGTVLESLSSYNKY..RYLIVLDSGHPQYSP---ftd.....
F0Y7E4_AURAN/94-137                    .aa---GARVEAR............Y..---..............RGKSKFYPGKIAKA---NDDG..SYDIAYDDGESE------anvi....
A0A1B0DMP7_PHLPP/933-984               ...LPVGTRVLAM............F..SAT..............-RRNLFYPGIVAEPTQETNRF..RYLVFFDDGYVQYVHPSD........
A0A226NX34_COLVI/172-223               ..h-YVGSRVVAK............Y..KDG..............-DQVWLYAGIVAETPNMKNKD..RFLIFFDDGYASYVKE--we......
T1JZ06_TETUR/317-372                   ..n-----RVIAH............Y..PTEssq.......plgeSNRQFLFSGLIAEVARRTNLF..RYLVFFDNGLVAYVPCD-t.......
A0A2I4AXH0_9TELE/277-328               ...LFVGARVVAK............Y..KDG..............-NLTWLYAGIIAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
G3PCX5_GASAC/263-314                   ...LYVGARVVAN............Y..KDG..............-SLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTLP-d.......
A0A182RJ96_ANOFN/542-597               ...LRLGTRIIAK............V..SSGv...........gdEASRSFYAGTVLESISAYNKF..RYLIIFDSGHTLYAPLS-d.......
SETB1_DROME/530-591                    ...LTIGTRVIAY............F..DGTtlsr.....gkdkgVVQSAFYPGIIAEPLKQANRY..RYLIFYDDGYTQYVPHRD........
A7SWQ8_NEMVE/108-157                   lkp---GARVIAQ............F..---..............RGSTKYYAGRIVEVDSSNSQQ.pRCHVQFDDGDKEWAE---ag......
A0A067BTL2_SAPPC/776-823               ...LKVGAKVEAK............Y..---..............KGKSKFYPGKITKVHGDG--S..SYDISYDDGETETRVES-d.......
B4LN52_DROVI/634-695                   ...LTIGTRVIAY............F..NGStlsr.....gkekgVVPSAFYPGIIAEPLKQANRF..RYLIFYDDGYTQYVQHND........
A0A182W7G5_9DIPT/379-433               ...LKLGTRVLAK............V..SSAe............gEESRSFYAGTVLESISAYNKF..RYLIIFDFGHTLYAP---isn.....
F1R772_DANRE/634-686                   ...LYIGCRVVAS............A..KSE..............NGKSLYNAGVMVELPERKNRM..RFLVFFDDGLATYLALP-d.......
A0A151JZN9_9HYME/336-387               ...IPVGTRVVAI............F..HDV..............-VSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
A0A182NTK7_9DIPT/485-536               ...LMIGTRVIAKp.........nsF..---..............-EERAFFVGTVIEAISSYNRY..RYLIIFDSGQAAYASI--ad......
A0A1D2MCJ8_ORCCI/131-186               ...LPVGARVIAK............Y..VDEn...........rsEDDGMFYAGVVADYPKITTKN..RYLIFFDDGSAQYVSQE-a.......
A0A182F1J2_ANOAL/493-550               ...LMLGTRVIAKi.........dsY..--Vgk..........ggSVQDEFYPGVVAESLGSYNRF..RYLIFYDDGYAQYVPPKD........
B0XAP5_CULQU/240-306                   ...LPLGTRVIAR............F..DAGsstappgkanqqmqAKTNAFYPGIIAESFGKYNRH..RYLIFFDDGYAQYVSHGD........
A0A0L0CQA2_LUCCU/775-836               ...LPIGTRVIAY............F..DATslar.....grekiNVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
M4AQ98_XIPMA/278-329                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
A0A0F8AEB0_LARCR/276-327               ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
A0A1S3MUY0_SALSA/348-399               ...LYVGARVVAK............Y..KDG..............-NQVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
G3H2X6_CRIGR/200-251                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A195DKZ4_9HYME/308-359               ...IPVGTRVVAI............F..HDV..............-VSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
A0A1S3WLW4_ERIEU/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
G3WHI1_SARHA/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
STB1B_DANRE/267-318                    ...LFVGARVVAR............Y..KDG..............-NQVWLYAGVVAEMPNSKNRM..RFLIFFDDGYASYVG---lpe.....
A0A182L1Y1_9DIPT/298-353               ..l-LLGTRVVARt.........ssA..TQD..............GMNRTFYAGTVLESLSSYNKY..RYLIVLDSGHPQYSP---ftd.....
H3CRK5_TETNG/255-306                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
I3JGZ5_ORENI/270-321                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
H2UKE0_TAKRU/263-314                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
L5K5I1_PTEAL/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
G1T430_RABIT/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
STB1A_DANRE/634-686                    ...LYIGCRVVAS............A..KSE..............NGKSLYNAGVMVELPERKNRM..RFLVFFDDGLATYLALP-d.......
A0A087XQP9_POEFO/213-261               ...LYIGARVVVR............C..QNN..............--KYRFRPGILAELPSRKNQF..RFLMFMDDH---------tpvyvgl.
K7ILY5_NASVI/334-385                   ...IPVTTRVVAI............F..QDS..............-YSSNYYSGVIAEPPKSTNKY..RYLVFFDDGYAQYVKHKH........
A0A154PEE2_9HYME/1169-1220             ...IPVGTRVVAV............F..RDV..............-TSSNFYSGVIAEPPKATNKY..RYLIFFDDGYAQYVEHR-h.......
A0A087XQN8_POEFO/152-200               ...LSIGCRVVVK............I..SNE..............--KVVYKPGIMAELPSRKNRM..RFLVYIDDHTPMY-----vgl.....
F4WGP5_ACREC/336-387                   ...IPVGTRVVAI............F..HDV..............-VSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
G5AJY0_HETGA/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A151IE23_9HYME/338-389               ...IPVGTRVVAI............F..HDV..............-NSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
E1BKH5_BOVIN/263-314                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
SETB1_DROPS/536-596                    ...LPIGTRVIAF............F..DGTlvgg......kekgVVQSAFYPGIIAEPLKQNNRF..RYLIFYDDGYTQYVHHSD........
A0A286ZY41_PIG/258-309                 ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKN..RFLIFFDDGYASYVTES-e.......
L8Y8R6_TUPCH/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
H9GIB6_ANOCA/264-315                   ...LHVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNAKNKM..RFLIFFDDGYASYVVQ--pe......
A0A2D0R211_ICTPU/292-343               ...LYVGARVVAK............Y..KDG..............-NQVWLYAGIVAEMPNSKNRM..RFLIFFDDGYASYVALP-d.......
A0A182ZZX8_9TREM/85-137                ...YPVGARVVSI............Y..RDD..............DGGIGYYSGLIAEPPSERNNH..RYLLFFDDGYTQYSP---pne.....
A0A158PJ89_ANGCS/274-327               ..y--LGLRVVALvt.......nvyF..---..............SDGPAWYSGTIGALPNSVHNK..EFLIFFDDGFEQYVQA--pl......
A0A182U139_9DIPT/345-400               ..l-LLGTRVVAR............T..-SSpt..........qdGMNRTFYAGTVLESLSSYNKY..RYLIVLDSGHPQYSP---ftd.....
A0A2I3TGZ2_PANTR/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
T0Q6A6_9STRA/287-333                   ...LKVGTKVEAR............Y..---..............KGKSKYYPGKIAKCHADE---..TYDIDYDDGEKEK-----rierd...
A0A1I8H7U6_9PLAT/287-339               ...YPVGARVVSS............Y..TDD..............RGLVFYYSAIVAEPPGERNSR..RYLLFFDDGYAQYVPPSD........
A0A074ZL29_9TREM/261-296               ...YPVGARVVSI............Y..RDE..............SGGIGYYSGLIAEPPSERNNH..R-----------------........
E9HRD0_DAPPU/291-347                   .fv--VGARVIAQ............Y.vGDNn...........efLEPLSYYAGMVAEEAKFLNQE..RHLVFFDQGYVQYCKHEQ........
A0A183BVS5_GLOPA/312-369               cpe---GTRVVAFs..........eL..--Aer.........qanVRVVKYFSGTIGVKPFTQNRF..EYLVFFDNGLDEYVRP--gd......
A0A1L8FBV0_XENLA/326-377               ...LTVGSRVVAK............Y..KDG..............-NQVWLYAGIVAEPPSSKNKM..RYLIFFDDGYASYVTHA-e.......
A0A096MVU1_PAPAN/258-309               ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A182GTC3_AEDAL/1123-1186             ...LPLGTRVIAR............F..NAGttqpt...lnksqqTKSTSFYPGIIAESFGKYNRN..RYLIFFDDGYAQYVTHGD........
A0A183KQK4_9TREM/28-75                 .qc-------EAI............Y..RDD..............TGGIGYYSGLIAEPPSERNNQ..RYLLFFDDGYTQYSP---pne.....
E2ATZ3_CAMFO/267-318                   ...IPVGTRVVAI............F..HDI..............-TSSNYYSGIIAEPPKSTNKY..RYLVFFDDGYAQYVTHKD........
A0A182PZR8_9DIPT/347-397               ...LMLGTRVIAK............P..HAE..............--ERAFFVGTVLESMSSYNRY..RYLIIFDSGQAAYASI--gd......
A0A182M0Q0_9DIPT/464-518               ...LKLGTRIIAK............V..GSGv............gEKSQSFFAGTVLESISAYNKF..RYLIIFDYGVTLYAPM--en......
A0A1U8DNI1_ALLSI/264-315               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQ--pe......
A0A2D0S206_ICTPU/498-549               ...LFVGCRVVAC............Y..RED..............-KQSWLHAAVVVEMPERRNRM..RFLVFFDDGRPAYISLP-d.......
A0A0L7QQN1_9HYME/333-384               ..i-SVGTRVVAV............F..KDV..............-SSSNFYSGVIAEPPKATNKY..RYLIFFDDGYAQYVEHKH........
A0A096LWV0_POEFO/294-345               ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
M3WBU8_FELCA/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1A6HLN9_NEOLE/140-191               ...LFVGSRVVAR............Y..KDG..............-NQVWLYXGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1I8BD64_MELHA/382-439               cpe---GTRVVAL............C..KRGvv.........qigSLFASYFEGTIAVKPFSQNRF..EYLVFFDSGIDAYVKPT-d.......
A0A0N0PDV3_PAPMA/1083-1132             ...LIIGTRIIAC............A..---..............EKTDSFYSGVVAEVPNPVNKF..RYLVFFDDGHAKYVQHAD........
M3XYW3_MUSPF/263-314                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
H0UWN1_CAVPO/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
J9P7P5_CANLF/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
X1WR37_ACYPI/260-314                   ...YPVGSRVIAK............F..QDMn............iELTDKFYVGVIAEPPKYLNNF..RYMIFFDDGYTQYVYHK-n.......
H0Z2Q1_TAEGU/185-236                   ..h-HVGRRVVAR............Y..KDG..............-NQMWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVKE--we......
T1IYR1_STRMM/200-254                   ...LPVGTRIIAK............Y..KDEn............wHQQDSMYAGIIAEPPKIMNKY..RYLIFFDDGFAQYTSHEH........
V9DXY3_PHYPR/36-80                     ..f-RVGTRVEAR............Y..---..............MGKDKYFKGTISRVNSDG---..TYVIEYDDGDKE------nrvp....
B7PPM4_IXOSC/278-332                   ...LPVGTRVVAT............Y..TDEs............wNQRQSLYAGLVAEPPKPLNRY..RYLVFFDDGYAQYVHID-k.......
A0A182G2F1_AEDAL/1126-1189             ...LPLGTRVIAR............F..DAGttqpt...lnksqqAKSTSFYPGIIAESFGKYNRN..RYLIFFDDGYAQYVTHGD........
A0A2D0S1X9_ICTPU/499-550               ...LFVGCRVVAC............Y..RED..............-KQSWLHAAVVVEMPERRNRM..RFLVFFDDGRPAYISLP-d.......
A0A1S3PXQ1_SALSA/395-446               ...LYVGVRVVAK............F..KDA..............-EQSWFYSGILAELPNRKNRM..RFLVFFDDGTPSYVGL--pd......
W4Z632_STRPU/31-85                     ...LAVGIRVVAS............YlvEEG..............AKTKGMYAGIIAEVPMKTNRG..RYLVFFDDGYAQYLSCEK........
B3SBL7_TRIAD/159-208                   ...LFVGCRGVAN............Y..SQC..............---GVYYGCIIVEKPCFNNGF..RYLVFFDDGFAEYFPAK-e.......
H2M4D0_ORYLA/244-295                   ...LFVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYV----ilpe....
G1RG51_NOMLE/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A7SWQ8_NEMVE/372-422                   ...VPIGARVIAA............F..---..............EGRCHYYKGRVTQI-DSTNPYapRYHVTYDDGDKGWVNCDK........
A0A067BTL2_SAPPC/245-290               ...LTVGTKVEAK............Y..---..............-KGKTFYPGKIAKAHADG---..SYDIDYDDGEIEK-----kvspd...
A0A1I8P1Y1_STOCA/939-1000              ...LPIGTRVIAY............F..DATslar.....grekiNVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
B4IH79_DROSE/211-272                   ...LTIGTRVIAY............F..DGTtlsr.....gkdkgVVQSAFYPGIIAEPLKQANRY..RYLIFYDDGYTQYVPHRD........
A0A067BTL2_SAPPC/137-182               ...LTVGTKVDAK............Y..---..............-KGKTYYPGTIARAHADD---..RYDIDYDDGEKET-----kvprd...
A0A0T6B9S1_9SCAR/480-541               ...LDVGARVIAV............F..REVllpe.....earerIKKDVFYPGIVAEPLQSSNKY..RYLIFFDDGYAQYVNF--sl......
H0X2F3_OTOGA/259-310                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
B3SBL5_TRIAD/207-272                   ...LRIGLRIIGLl..........sY..ISRvsllf...fipafyGIIKKYKGGLIAEVPSESNND..RYLIFFDDGFVSYLHED-k.......
A0A0P7TYV5_9TELE/200-251               ...LYVGARVVAK............Y..KDG..............-NQVWLYAGIVAEMPNSKNRM..RFLIFFDDGYASYVG---lpe.....
H2UKE1_TAKRU/260-311                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
H2UKD9_TAKRU/263-314                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
A0A287BEQ3_PIG/258-309                 ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKN..RFLIFFDDGYASYVTES-e.......
C3Y5H5_BRAFL/366-420                   ...LHAGSRIVGQ............Y..VDEe............gDSVQYLYAGIVAELPSKMNRS..RYLIFFDDGFATYLKRD-q.......
G3STG1_LOXAF/258-309                   ...LYVGSRVVAK............Y..KDG..............-SQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
H3ASP5_LATCH/251-302                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAEPPNVKNKM..RFLIFFDDGYASYVTQS-e.......
T1FPH6_HELRO/180-232                   ..m-AVGTRVIAL............Y..RDI..............SVVNFWYAGVVAEGPSRTNFF..RYLVFFDDGYAQYCAV--cd......
I3M8I9_ICTTR/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A0R3W9Y8_TAEAS/270-322               ...YPVGARVVAL............Y..QDA..............NGVSAYYSGIVGEPPNSYNNY..RYLIFFDDGYAYYAQSD-c.......
B4KTI6_DROMO/621-682                   ...LTIGTRVIAY............F..NGStlsr.....gkekgVVPSAFYPGIIAEPLKQANRF..RYLIFYDDGYTQYVQHND........
B7P544_IXOSC/36-90                     ...LPIGTRVVAT............Y..TDEs............wNQRQSLYAGLIAEPPKPLNRY..RYLVFFDDGYAQYVHID-k.......
A0A2K5P577_CERAT/243-294               ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A182J3P8_9DIPT/446-508               lhq---GMRIIAKvdpadleetgdeY..LKE..............-SGTAFYAGVIAETLSTYNNH..RYLVIFDNGYTHYAQ---pw......
S7MVH5_MYOBR/274-325                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1L8F4F5_XENLA/265-316               ...LTVGSRVVAK............Y..KDG..............-NQVWLYAGIVAEPPSNKNKM..RYLIFFDDGYASYVTHP-e.......
A0A2I4AYF4_9TELE/271-321               ...LYVGARVIIQ............S..LDD..............--ESSFQPGILSELPSRKNRL..RFLIFLDDHSVLYVS---lpa.....
K1R5K2_CRAGI/527-579                   ...VSVGTRVVAL............Y..KDE..............ESMASFYAGIVAETPNQRNAY..RYLIFFDDGYAQYSRSDD........
B2GRL9_DANRE/267-318                   ...LFVGARVVAR............Y..KDG..............-NQVWLYAGVVAEMPNSKNRM..RFLIFFDDGYASYVG---lpe.....
F7A203_CALJA/263-314                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A067BTL2_SAPPC/564-610               ...LKVGARIEAR............Y..---..............KGKSKYYPGKITKCHSDG---..SYDIDYDDGEVESRVEKD........
A0A094ZXJ4_SCHHA/1-46                  ..l--------AI............Y..RDD..............TGGIGYYSGLIAEPPSERNNQ..RYLLFFDDGYTQYSP---pne.....
A0A0C2MIC2_THEKT/1-50                  .mg--IGTRVVAR............W..---..............PGISNYLPGNISSIDVKENST..KYLISFDDGDNHWNSL--dq......
A0A1W4ULS7_DROFC/558-619               ...LTIGTRVIAY............F..DGTtlsr.....ckekgVVQSAFYPGIIAEPLKQANRY..RYLIFYDDGYTQYVPHRD........
A0A1D2MW35_ORCCI/388-445               ...LPVGTRVISK............F..KDLlm.........nnpGFNGKYFAGIVAEAPELQNDN..RYLIFYDDGFVQYVDAA-d.......
A7SP53_NEMVE/1997-2048                 ...LKLGTKVIAK............F..KKN..............--AKTYFSGQIAEVDKTREDK.kIYKVNFDDGDEGWASL--yh......
J9K0P6_ACYPI/360-414                   ..f-PVGCRVIAK............F..TDPn............sKYTDEFYAGLIAEPPKMLNNF..RYLIFFDDGCAQYRHHQD........
W5L9Z5_ASTMX/251-302                   ...LYVGARVVAK............Y..KDG..............-NQVWLYAGIVAEMPNSKNRM..RFLIFFDDGYASYVGL--pd......
W5QI91_SHEEP/263-314                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A182JXT1_9DIPT/460-515               ...LRLGTRVVAS............I..SSVt...........ndPICRTFYAGTVMESMSSYNKF..RYLIIFDSGHTQYSP---ftd.....
F1SS95_PIG/258-309                     ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKN..RFLIFFDDGYASYVTES-e.......
G1L2Y3_AILME/263-314                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
Q17D97_AEDAE/75-138                    ...LPLGTRVIAR............F..DAGttqpt...lnksqqAKSNSFYPGIIAESFGKYNRN..RYLIFFDDGYAQYVTHGD........
A0A182XZV8_ANOST/514-569               ...LKLGTRVIAK............V..CSTt...........geAASRAFYAGTVLESISSYNKF..RYLIIFDSGHTLYAPL--qe......
A0A1U7T5F2_TARSY/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNNKNKF..RFLIFFDDGYASYVTQS-e.......
Q7Q3P9_ANOGA/271-326                   ..l-LLGTRVVARt.........ssA..TQD..............GMNRTFYAGTVLESLSSYNKY..RYLIVLDSGHPQYSP---ftd.....
A0A182HV29_ANOAR/527-582               ..l-LLGTRVVAR............T..-SSpt..........qdGLNRTFYAGTVLESLSSYNKY..RYLIVLDSGHPQYSP---ftd.....
A0A151M5C4_ALLMI/328-379               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQ--pe......
G7YBR9_CLOSI/276-328                   ...YPVGARVVSI............Y..RDE..............SGGIGYYSGLIAEPPSERNNH..RYLLFFDDGYTQYSP---pne.....
A0A1S3CUX9_DIACI/366-414               ...YRVGMRVIAK............F..AS-..............---TDYYSGTVAEIPKETNKW..RYLIFFDDGYTSYSCHED........
A0A1J1INV5_9DIPT/933-991               ...LKIGARVIAQnp........raH..--Skt..........hkDIHKRFCPGVIGEKLSKYNKS..RYLVFYDYGQVNYATPQ-q.......
X1X4B9_ACYPI/284-323                   ...YPVGSRVIAK............F..QDMn............iQLTDKFYVGVIAEPPKYLNNF..RY----------------v.......
K7B3J1_PANTR/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1I8I8L3_9PLAT/927-991               ..c-PVGTRVVSTva.......dpdY..ADEgpd.......aeadGDETPRYAGIVAESPGEANKF..RYLIFFDDGYCQYSE---qaa.....
A0A232F7G5_9HYME/782-833               ...IPVTTRVVAI............F..QDT..............-YSSNYYSGVIAEPPKSTNKY..RYLVFFDDGYAQYVKHKH........
A7T0X8_NEMVE/351-401                   ...VPVGARVIAS............F..---..............QGRPNFYKGRVTKI-DSTNHYapRYHVTYDDGDKGWVNCD-q.......
A0A1D2N373_ORCCI/234-291               ...LPIGCRIIAK............F..KDLlr.........tdgEVDGMLYAGVTAEVPKNSNKQ..RYLIFFDDGYAQYVSQA-d.......
A0A183NAC3_9TREM/202-254               ...YPVGARVVSI............Y..RDD..............AGGIGYYSGLIAEPPSERNNQ..RYLLFFDDGYTQYSP---pne.....
A0A1B0AF68_GLOPL/643-705               ...LPTGARVIAY............F..DATsltrg....kekvtTVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
G5E8N3_MOUSE/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
H3GBS4_PHYRM/71-118                    ...LSVGTRVQAF............W..REE..............---NEWFDGTILHV-EEGNER..RYYVHYDDGEEQW-----evld....
A0A1I8JEB6_9PLAT/287-339               ...YPVGARVVSS............Y..TDD..............RGLVFYYSAIVAEPPGERNSR..RYLLFFDDGYAQYVPPSD........
A0A226F0L3_FOLCA/606-663               ...LIVGTRIIAK............F..RDElk.........mepIGDGQYYAGIVAEHPTPQNKF..RYLIFFDDGYAQYVGIK-d.......
A0A1W4XQY0_AGRPL/491-538               ...LDVGTRVIAV............F..RETatnm......etkkHKKETFFPGIVAEPLSAANRY..R-----------------svli....
A0A068XTU2_ECHMU/271-317               ..p-------VAL............Y..QDA..............NGVSAYYSGIVGEPPNSYNNY..RYLIFFDDGYAYYAQSD-c.......
A0A182WT32_ANOQN/517-572               ..l-LLGTRVVAR............T..-SSpt..........qdGMNRTFYAGTVLESLSSYNKY..RYLIVLDSGHPQYSP---ftd.....
A0A2D0R1U2_ICTPU/292-343               ...LYVGARVVAK............Y..KDG..............-NQVWLYAGIVAEMPNSKNRM..RFLIFFDDGYASYVALP-d.......
A0A0R3TLV4_HYMNN/269-321               ...YPVGARVVAR............Y..IDP..............HGVSDYYSGTIGEPPKLDNEY..RYLIFFDDGYAYYAQP--gc......
A0A0G2K5A7_RAT/278-329                 ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A139WDT3_TRICA/396-456               ...LETGTRVIAV............F..KEIgptg......earkIRYEPFYPGVVAEPPVAQNKY..RYLIFFDIGYSQYVNY--tn......
A0A093J165_EURHL/69-119                ..h-YVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVK---dw......
T0R2Y4_9STRA/58-104                    .wv--VGAKVEAK............Y..---..............KGKSKFYPGTIAKVHTDA---..SFDIDYDDGEKEKRVEKD........
I3JGZ4_ORENI/276-327                   ...LYVGARVVAK............Y..KDG..............-NLVWLYAGIVAEMPNNKNRM..RFLIFFDDGYASYVTL--pe......
J9JU99_ACYPI/276-330                   ..y-SVGSRVIAK............F..QDMn............iELTDKFYVGVIAEPPKYLNNF..RYMIFFDDGYTQYVYHK-n.......
D6WYT6_TRICA/154-214                   ...VPVGSRVVAH............Q..-RGikpt.....geikrNGRRNFQLGVVAELPSQLNGS..RYLVIFDNGAWNYIESK-l.......
T1JK41_STRMM/78-129                    ...LSVGTRVVAL............Y..AGN..............GKSAVYLAGIIAEPPGMANKH..RYLIFFDDGSTQYV----gil.....
A0A0L8H098_OCTBM/1-46                  ..m----------............Y..RDEe............aNPSTSFYAGIVAEVPTNRNRH..RFLIFFDDGYAQYCLP--ke......
A0A2I3H4W3_NOMLE/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A164ZKP0_9CRUS/306-362               ..f-AVGARIIAQ............Y..VGEky..........emLEPLAYYAGIIAEEAKSLTQE..RYLVFFDQGYAQYCKHEQ........
A0A2B4S578_STYPI/433-482               ...LNVGSRVVGI............Y..---..............GKLDVLYAGIVAENACGENKN..RYLVFFDDGFAQYLPVK-k.......
A0A1D2ME92_ORCCI/369-426               ..h-PVGTRVVAD............L..RDEle.........idpEDDGEFYVGVVGEIPKPSTKN..RYLIFFDNGRTKYVTSE-r.......
A0A1U7QR72_MESAU/129-180               ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1S3WLW5_ERIEU/71-122                ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
G7NTT5_MACFA/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A026W0J7_OOCBI/337-388               ...IPVGTRVVAI............F..HDV..............-SSSNYYSGIIAEPPKYTNKY..RYLVFFDDGYAQYVTHDD........
A0A151WI55_9HYME/337-388               ...IPVGTRVVAI............F..HDV..............-VSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
A0A1B0CWL2_LUTLO/1435-1486             ...LSVGCRVVAQ............F..SAA..............-RRKLYYPGIVAEPTQETNKF..RYLIFFDDGYVQYVF---pgd.....
G3WHI2_SARHA/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
H9L3I9_CHICK/390-441                   ..h-YVGSRVVAK............Y..KDG..............-DQVWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVKE--we......
A0A1S3A9W0_ERIEU/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
G5A2N1_PHYSP/72-113                    .ic--VGTRVLCR............Y..---..............DGGEEYYPGQVSDV---QENG..RYTIAYDDGEV-------ee......
A0A0K0D2S9_ANGCA/407-460               ..y--LGLRVVALvt.......nvyF..SD-..............--EPAWYSGTIGALPNSVHNK..EFLIFFDDGFEQYVQA--pl......
A0A158QFJ0_HYMDI/269-321               ...YPVGARVVAR............Y..IDP..............HGVSDYYSGTIGEPPKLDNEY..RYLIFFDDGYAYYAQPD-c.......
E2QW40_CANLF/261-312                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
L5MET7_MYODS/307-344                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RH----------------al......
B3MC21_DROAN/538-599                   ...LTIGTRVIAY............F..DGStlsr.....gkdkgVVQSAFYPGIIAEPLKQANRF..RYLIFYDDGYTQYVQHRD........
A0A286ZV06_PIG/120-171                 ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKN..RFLIFFDDGYASYVTES-e.......
A0A2D0R3I4_ICTPU/177-228               ...LYVGARVVAK............Y..KDG..............-NQVWLYAGIVAEMPNSKNRM..RFLIFFDDGYASYVALP-d.......
A0A1A9X4V2_9MUSC/633-694               ...LPTGARVIAY............F..DASsltr.....gkdkvTVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
A0A2D0S1X4_ICTPU/499-550               ...LFVGCRVVAC............Y..RED..............-KQSWLHAAVVVEMPERRNRM..RFLVFFDDGRPAYISLP-d.......
SETB1_MOUSE/258-309                    ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A1D2M340_ORCCI/138-191               ...LPVGTRVIAKl.........tgF..AEN..............--DGQIYAGVVGDVPKPNNKN..RYLIFVDNKMVQYVESC-d.......
A0A0N0PDV3_PAPMA/1214-1261             .tr----TRIIAC............A..---..............EKTDSFYSGVVAEVPNPVNKF..RYLVFFDDGHAKYVQHAD........
A0A1V9X194_9ACAR/377-426               ...LQLGSRIVSQ............Y..VP-..............--DKQFYAGVVIEYPKWQNRH..RYLILFEDGYWQYSQPS-n.......
B4MP92_DROWI/111-175                   ...LPIGTRVIAY............F..DGStlirgr..erkergVVQSAFYPGIIAEPIKQANRF..RYLIFYDDGYTQYVLHKD........
A0A1U8DNH9_ALLSI/264-315               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQ--pe......
W6UDU9_ECHGR/150-202                   ...YPVGARVVAL............Y..QDA..............NGVSAYYSGIVGEPPNSYNNY..RYLIFFDDGYAYYAQSD-c.......
A0A2K5JAN0_COLAP/243-294               ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
G1MQP3_MELGA/262-313                   ..h-YVGSRVVAK............Y..KDG..............-DQVWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVKE--we......
A0A151HXM5_9HYME/336-387               ...IPVGTRVVAI............F..HDV..............-VSNNYYSGIIAETPKSINKY..RYLVFFDDGYAQYVVHND........
A0A2I3HIG4_NOMLE/258-309               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
F0Y7E4_AURAN/217-262                   ..f-AVGAKVEAR............Y..---..............RGKSKYYAGVIAKDNGDG---..TYDIDYDDGEKE------skvae...
A0A1S3F3U0_DIPOR/258-295               ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RH----------------vl......
A0A067BTL2_SAPPC/630-674               ...LAVGTKVEAK............Y..---..............-KGKTFYPGTIAKAHADG---..SYDINYDDGEIE------kkvpp...
A0A1I8MWS1_MUSDO/704-765               ...LPIGTRVIAY............F..DATslar.....grekiNVQSAFYPGIIAEPLKPNNKF..RYLIFYDDGYTQYVYHKD........
G1PG25_MYOLU/265-316                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
U4U7K2_DENPD/298-358                   ...LTVGSRVLSQ............F..KETnava......qgkrPRAVPYYAGVVGEHPVENNHF..RYLIFFDIGYAQYVQHSD........
A0A068XA93_HYMMI/269-321               ...YPVGARVVAR............Y..IDP..............HGVSDYYSGTIGEPPKLDNEY..RYLIFFDDGYAYYAQPS-c.......
A0A087TZN4_9ARAC/85-147                ...VPVGTRIIAVcnlem.dtlsarY..TDE..............-FKSHLYAGIVAEPPKVTNRG..RYLIFFDDGYAQYVYHED........
T0R2Y4_9STRA/117-163                   ..f-RVGSKVEAR............Y..---..............NGKLKYYPGKIARCHANG---..TYDIDYDDGEVETR----vdka....
A0A093RE21_PYGAD/194-245               ..h-YVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVM---ewe.....
A0A182PD15_9DIPT/352-407               ...LRLGTRVIAR............I..SSNp...........ndAMNRAFYAGTVLESISNYNNF..RYLITFDSGHTLYAPF--td......
H9G2L0_MACMU/258-309                   ...LFVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
U3J2K8_ANAPL/252-303                   ..h-YVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKD..RFLIFFDDGYASYVKE--we......
S9XWZ0_CAMFR/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A0R3X6T6_HYDTA/271-317               ..p-------VAL............Y..QDA..............NGVSAYYSGIVGEPPNSYNNY..RYLIFFDDGYAYYAQSD-c.......
A0A2D0S2U9_ICTPU/499-550               ...LFVGCRVVAC............Y..RED..............-KQSWLHAAVVVEMPERRNRM..RFLVFFDDGRPAYISLP-d.......
T0RJS0_9STRA/107-152                   ...LAVGTKVEAK............Y..---..............-KGKTFYPGKITRCHADG---..SYDIDYDDGEKEKRVEKD........
T0Q6A6_9STRA/138-183                   ..f-AVGTKVDAK............Y..---..............-KGKTFYPGTIARAHADD---..RYDIDYDDGEKET-----kvprd...
A7T4H9_NEMVE/317-368                   ...LKLGTKVIAK............F..KKN..............--AKTYFSGQIAEVDKTREDK.kIYKVNFDDGDEGWASL--yh......
E9PQM8_HUMAN/258-309                   ...LYVGSRVVAK............Y..KDG..............-NQVWLYAGIVAETPNVKNKL..RFLIFFDDGYASYVTQS-e.......
A0A088APQ1_APIME/334-384               ...IPVGTRVVAI............F..KDV..............--SSNFYSGVIAEPPKATNKY..RYLIFFDDGYAQYVVHKD........
F0Y7E4_AURAN/803-848                   ..f-AVGAKVEAR............Y..---..............RGKSKYYAGVIAKDNGDG---..TYDIDYDDGEKE------skvae...
#=GC SS_cons                           ...--TT-EEEEE............E..EET..............-TEEEEEEEEEEE-S-TTTTS..-EEEEETTS-EEEE-GG-G.......
#=GC seq_cons                          ...LhVGoRVVA+............Y..cDs...............spshhYuGIVAEsPsspN+h..RaLIFFDDGYApYVs.t.........
//
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