GenomeNet

Database: Pfam
Entry: TolA
LinkDB: TolA
Original site: TolA 
#=GF ID   TolA
#=GF AC   PF06519.13
#=GF DE   TolA C-terminal
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_16081 (release 10.0)
#=GF GA   20.80 20.80;
#=GF TC   20.80 20.80;
#=GF NC   20.70 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0428
#=GF RN   [1]
#=GF RM   12423782
#=GF RT   The Tol proteins of Escherichia coli and their involvement in
#=GF RT   the translocation of group A colicins. 
#=GF RA   Lazzaroni JC, Dubuisson JF, Vianney A; 
#=GF RL   Biochimie 2002;84:391-397.
#=GF DR   INTERPRO; IPR014161;
#=GF DR   SCOP; 1lr0; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several bacterial TolA proteins as well
#=GF CC   as two eukaryotic proteins of unknown function.  Tol proteins
#=GF CC   are involved in the translocation of group A colicins. Colicins
#=GF CC   are bacterial protein toxins, which are active against
#=GF CC   Escherichia coli and other related species (See Pfam:PF01024). 
#=GF CC   TolA is anchored to the cytoplasmic membrane by a single
#=GF CC   membrane spanning segment near the N-terminus, leaving most of
#=GF CC   the protein exposed to the periplasm [1].
#=GF SQ   413
#=GS A0A2I0FRY4_9GAMM/307-401  AC A0A2I0FRY4.1
#=GS A0A068QPS4_9GAMM/247-342  AC A0A068QPS4.1
#=GS A0A0Q0J4M9_9GAMM/210-308  AC A0A0Q0J4M9.1
#=GS A0A1T4UIW4_9GAMM/273-368  AC A0A1T4UIW4.1
#=GS J2LS40_KLEPN/1-77         AC J2LS40.1
#=GS A0A085U465_YERRU/288-382  AC A0A085U465.1
#=GS A0A233REV9_9GAMM/322-416  AC A0A233REV9.1
#=GS A0A381H6F7_CITKO/259-353  AC A0A381H6F7.1
#=GS A0A5J5G0K9_9GAMM/291-385  AC A0A5J5G0K9.1
#=GS A0A0L0UL91_9BASI/11-105   AC A0A0L0UL91.1
#=GS A0A220VE13_9GAMM/256-351  AC A0A220VE13.1
#=GS A0A5S3P2D3_9GAMM/202-298  AC A0A5S3P2D3.1
#=GS A0A1B7UM65_9GAMM/209-304  AC A0A1B7UM65.1
#=GS A0A1T0ARL5_9PAST/386-482  AC A0A1T0ARL5.1
#=GS A0A411PLL5_9GAMM/219-314  AC A0A411PLL5.1
#=GS I9P3P5_9ALTE/219-315      AC I9P3P5.1
#=GS A0A4Q5MA86_9GAMM/212-307  AC A0A4Q5MA86.1
#=GS A0A4R5H9M6_9ALTE/205-300  AC A0A4R5H9M6.1
#=GS A0A1C4AZK6_9GAMM/292-386  AC A0A1C4AZK6.1
#=GS H2IWI9_RAHAC/310-404      AC H2IWI9.1
#=GS A0A0M0HTC4_VIBNE/234-332  AC A0A0M0HTC4.1
#=GS A6T6G5_KLEP7/340-434      AC A6T6G5.1
#=GS A0A2A7U0T2_EDWTA/301-395  AC A0A2A7U0T2.1
#=GS Q5QYU9_IDILO/168-263      AC Q5QYU9.1
#=GS A0A3N1J980_9ENTR/27-123   AC A0A3N1J980.1
#=GS A0A2S0IP62_9GAMM/193-288  AC A0A2S0IP62.1
#=GS A0A6I4L2Q1_9ENTR/349-443  AC A0A6I4L2Q1.1
#=GS A0A4Q7ZAX0_9GAMM/133-229  AC A0A4Q7ZAX0.1
#=GS A0A1Y6ISK2_9VIBR/233-332  AC A0A1Y6ISK2.1
#=GS A0A248KJH7_9ENTR/322-417  AC A0A248KJH7.1
#=GS A0A553L258_9ALTE/192-287  AC A0A553L258.1
#=GS A0A1V0KUB2_9GAMM/196-292  AC A0A1V0KUB2.1
#=GS A0A545UBS9_9GAMM/193-286  AC A0A545UBS9.1
#=GS D4E9I2_SEROD/298-392      AC D4E9I2.1
#=GS A0A2N5EQT9_9GAMM/356-450  AC A0A2N5EQT9.1
#=GS A0A6I4L0L7_9ENTR/50-141   AC A0A6I4L0L7.1
#=GS A0A2S4MTW7_SHIFL/317-411  AC A0A2S4MTW7.1
#=GS Q8ZQT6_SALTY/311-405      AC Q8ZQT6.1
#=GS A0A1W6BAM4_9GAMM/20-106   AC A0A1W6BAM4.1
#=GS A0A097R096_HAFAL/315-409  AC A0A097R096.1
#=GS A0A2C8CZ85_9GAMM/167-261  AC A0A2C8CZ85.1
#=GS L8JGN7_9GAMM/256-351      AC L8JGN7.1
#=GS A0A2S7UYN0_9GAMM/239-334  AC A0A2S7UYN0.1
#=GS A0A3D9ULM2_9GAMM/240-334  AC A0A3D9ULM2.1
#=GS A0A3S5EYR3_ACTEU/3-58     AC A0A3S5EYR3.1
#=GS A0A4R6UM55_9GAMM/206-300  AC A0A4R6UM55.1
#=GS A0A0J8YIE1_9GAMM/143-237  AC A0A0J8YIE1.1
#=GS A0A0F5AP25_9GAMM/235-330  AC A0A0F5AP25.1
#=GS R9PPN1_AGAAL/233-328      AC R9PPN1.1
#=GS A0A495RKH3_9GAMM/263-356  AC A0A495RKH3.1
#=GS I1DZ02_9GAMM/206-301      AC I1DZ02.1
#=GS Q9CM70_PASMU/291-386      AC Q9CM70.1
#=GS A0A1J7CJQ2_9GAMM/78-172   AC A0A1J7CJQ2.1
#=GS A1SSW3_PSYIN/205-300      AC A1SSW3.1
#=GS A4W888_ENT38/310-404      AC A4W888.1
#=GS A0A4R1FVR7_9PAST/295-390  AC A0A4R1FVR7.1
#=GS A0A0F7HC92_SERFO/304-398  AC A0A0F7HC92.1
#=GS K6YVP7_9ALTE/191-286      AC K6YVP7.1
#=GS A0A2Z6UH57_GLASK/162-257  AC A0A2Z6UH57.1
#=GS A0A1B7JZ04_9GAMM/270-367  AC A0A1B7JZ04.1
#=GS A0A0J5S3J2_9PAST/312-407  AC A0A0J5S3J2.1
#=GS A0A2V1HH64_9GAMM/270-364  AC A0A2V1HH64.1
#=GS A0A1I1UV42_9GAMM/206-301  AC A0A1I1UV42.1
#=GS A0A2M8RX58_9PAST/308-403  AC A0A2M8RX58.1
#=GS Q8EBA2_SHEON/18-117       AC Q8EBA2.1
#=GS R4I1C1_9GAMM/190-284      AC R4I1C1.1
#=GS Q9KR10_VIBCH/254-353      AC Q9KR10.1
#=GS Q9KR10_VIBCH/254-353      DR PDB; 6FW4 A; 22-119;
#=GS A0A4R2FGW6_9GAMM/220-315  AC A0A4R2FGW6.1
#=GS A0A0H3GU69_KLEPH/343-437  AC A0A0H3GU69.1
#=GS A0A1H9ZUL3_9GAMM/316-411  AC A0A1H9ZUL3.1
#=GS A0A2C6DNA2_9GAMM/250-344  AC A0A2C6DNA2.1
#=GS W0LCR3_9GAMM/295-389      AC W0LCR3.1
#=GS Q8EDJ7_SHEON/245-340      AC Q8EDJ7.1
#=GS A0A2P5GRA9_9ENTR/302-397  AC A0A2P5GRA9.1
#=GS A0A0J8YH36_9GAMM/18-100   AC A0A0J8YH36.1
#=GS Q7VR85_BLOFL/337-432      AC Q7VR85.1
#=GS A0A0F4NXF8_9VIBR/241-339  AC A0A0F4NXF8.1
#=GS A0A2T3MPL6_9GAMM/15-114   AC A0A2T3MPL6.1
#=GS A0A094JBP3_9GAMM/222-317  AC A0A094JBP3.1
#=GS A0A178KMC5_9GAMM/242-337  AC A0A178KMC5.1
#=GS A0A4U2UEP5_9ENTR/294-388  AC A0A4U2UEP5.1
#=GS A0A4Q9XMR2_9ALTE/182-277  AC A0A4Q9XMR2.1
#=GS A0A1I0GU19_THASX/182-278  AC A0A1I0GU19.1
#=GS M4R7L5_BIBTR/301-396      AC M4R7L5.1
#=GS A0A1M5QSS8_9GAMM/202-297  AC A0A1M5QSS8.1
#=GS W1IW62_9GAMM/253-347      AC W1IW62.1
#=GS D4GL71_PANAM/47-133       AC D4GL71.1
#=GS A0A263HBC1_9PAST/336-431  AC A0A263HBC1.1
#=GS A0A0A3APG6_9PAST/285-380  AC A0A0A3APG6.1
#=GS A0A0E3U405_9ENTR/234-327  AC A0A0E3U405.1
#=GS M1STN5_MORMO/264-358      AC M1STN5.1
#=GS A0A1V3TTG5_9PAST/347-442  AC A0A1V3TTG5.1
#=GS A0A420XH29_9PAST/327-419  AC A0A420XH29.1
#=GS H5TBL3_9ALTE/187-282      AC H5TBL3.1
#=GS A0A432WGG9_9GAMM/199-294  AC A0A432WGG9.1
#=GS A0A370QNQ4_9ENTR/37-124   AC A0A370QNQ4.1
#=GS A0A0J8VRE4_9ENTR/345-439  AC A0A0J8VRE4.1
#=GS A0A0A2VY63_BEABA/460-554  AC A0A0A2VY63.1
#=GS A0A432X047_9GAMM/192-287  AC A0A432X047.1
#=GS A0A250B872_9ENTR/312-406  AC A0A250B872.1
#=GS A0A1V4B1H5_9PAST/267-362  AC A0A1V4B1H5.1
#=GS A0A269PKD5_9GAMM/201-296  AC A0A269PKD5.1
#=GS O82913_ECO57/49-141       AC O82913.1
#=GS J5KQA3_PASMD/121-168      AC J5KQA3.1
#=GS A0A653FVJ3_9CAUD/46-140   AC A0A653FVJ3.1
#=GS E3G3S2_ENTLS/324-418      AC E3G3S2.1
#=GS A0A1E7Z469_9GAMM/247-341  AC A0A1E7Z469.1
#=GS A0A427TZS5_9VIBR/227-325  AC A0A427TZS5.1
#=GS A0A077PC43_XENBV/270-364  AC A0A077PC43.1
#=GS C0B249_9GAMM/16-109       AC C0B249.1
#=GS E0SFP4_DICD3/301-395      AC E0SFP4.1
#=GS A0A085JBT9_9GAMM/127-221  AC A0A085JBT9.1
#=GS A0A097R335_HAFAL/37-130   AC A0A097R335.1
#=GS G2H009_9ENTR/249-342      AC G2H009.1
#=GS A0A514EUU8_9ENTR/361-456  AC A0A514EUU8.1
#=GS A0A3N1IUP9_9ENTR/311-405  AC A0A3N1IUP9.1
#=GS Q8X965_ECO57/298-392      AC Q8X965.1
#=GS Q8X965_ECO57/298-392      DR PDB; 2X9A D; 332-418;
#=GS Q8X965_ECO57/298-392      DR PDB; 2X9A B; 332-418;
#=GS A0A148KNI7_9ALTE/197-292  AC A0A148KNI7.1
#=GS A0A0J8YV77_9GAMM/347-441  AC A0A0J8YV77.1
#=GS A0A2N7DHY5_9VIBR/270-368  AC A0A2N7DHY5.1
#=GS G4QKX6_GLANF/188-282      AC G4QKX6.1
#=GS A0A1E7Q8H7_9GAMM/208-303  AC A0A1E7Q8H7.1
#=GS A0A6I4L8U5_9ENTR/46-140   AC A0A6I4L8U5.1
#=GS A0A1X1ERL5_PANCY/36-119   AC A0A1X1ERL5.1
#=GS A0A2N1IFT7_9GAMM/214-310  AC A0A2N1IFT7.1
#=GS A0A089Q109_9ENTR/335-429  AC A0A089Q109.1
#=GS F7S008_9GAMM/219-314      AC F7S008.1
#=GS A0A5B7YFP0_9ALTE/178-273  AC A0A5B7YFP0.1
#=GS A0A090QR00_9GAMM/253-348  AC A0A090QR00.1
#=GS D2U0F2_9GAMM/233-330      AC D2U0F2.1
#=GS A0A161ZW86_9GAMM/214-309  AC A0A161ZW86.1
#=GS A0A2M8S0E2_9PAST/303-398  AC A0A2M8S0E2.1
#=GS A0A090P638_9VIBR/254-352  AC A0A090P638.1
#=GS A0A0J5NIV9_PLUGE/361-455  AC A0A0J5NIV9.1
#=GS A0A4R4F9K1_9GAMM/188-283  AC A0A4R4F9K1.1
#=GS B7VMJ1_VIBA3/218-316      AC B7VMJ1.1
#=GS Q6D7F3_PECAS/298-392      AC Q6D7F3.1
#=GS A0A432ZPP9_9GAMM/171-266  AC A0A432ZPP9.1
#=GS A0A4Y6IDM9_9GAMM/240-335  AC A0A4Y6IDM9.1
#=GS A0A2A7U525_EDWTA/43-133   AC A0A2A7U525.1
#=GS A0A1T0BC75_9PAST/264-359  AC A0A1T0BC75.1
#=GS A0A090V3Z4_PSEVU/332-426  AC A0A090V3Z4.1
#=GS A0A2N0X374_9GAMM/238-333  AC A0A2N0X374.1
#=GS A0A380U6I0_9PAST/264-359  AC A0A380U6I0.1
#=GS TOLA_ECOLI/325-419        AC P19934.1
#=GS TOLA_ECOLI/325-419        DR PDB; 3QDP A; 334-419;
#=GS TOLA_ECOLI/325-419        DR PDB; 3QDR A; 329-419;
#=GS TOLA_ECOLI/325-419        DR PDB; 1TOL A; 125-211;
#=GS TOLA_ECOLI/325-419        DR PDB; 1S62 A; 4-98;
#=GS A0A514ERQ0_9ENTR/49-140   AC A0A514ERQ0.1
#=GS A0A1N6S368_9GAMM/284-379  AC A0A1N6S368.1
#=GS E1SLC7_FERBD/209-304      AC E1SLC7.1
#=GS A0A0M2KLM1_9GAMM/286-380  AC A0A0M2KLM1.1
#=GS A0A3A6UMP4_9GAMM/211-306  AC A0A3A6UMP4.1
#=GS A0A085HKP0_9GAMM/236-330  AC A0A085HKP0.1
#=GS A0A2A2H4E8_9GAMM/233-330  AC A0A2A2H4E8.1
#=GS A0A1R4B204_9VIBR/253-352  AC A0A1R4B204.1
#=GS J2E7G7_KLEPN/365-459      AC J2E7G7.1
#=GS A0A2S6VQ90_9GAMM/354-448  AC A0A2S6VQ90.1
#=GS A0A1Y0CVI8_9GAMM/289-383  AC A0A1Y0CVI8.1
#=GS A0A1D3TUN3_9FIRM/34-128   AC A0A1D3TUN3.1
#=GS R8AUW7_PLESH/291-386      AC R8AUW7.1
#=GS A0A1M5R630_9ALTE/163-256  AC A0A1M5R630.1
#=GS A0A2T4CR33_9ALTE/121-216  AC A0A2T4CR33.1
#=GS A0A0U5L1V3_9GAMM/25-115   AC A0A0U5L1V3.1
#=GS A0A4Q8UHT0_9ALTE/164-259  AC A0A4Q8UHT0.1
#=GS A0A396TT75_9GAMM/197-293  AC A0A396TT75.1
#=GS A0A545TD09_9GAMM/201-294  AC A0A545TD09.1
#=GS D0YYS2_PHODD/232-327      AC D0YYS2.1
#=GS W7R089_9ALTE/200-295      AC W7R089.1
#=GS A0A085G940_9ENTR/1-55     AC A0A085G940.1
#=GS B2VBQ8_ERWT9/334-428      AC B2VBQ8.1
#=GS A0A1A6KKQ4_9VIBR/250-348  AC A0A1A6KKQ4.1
#=GS A0A514ESJ8_9ENTR/47-139   AC A0A514ESJ8.1
#=GS A0A1E7Z7H2_9ALTE/173-268  AC A0A1E7Z7H2.1
#=GS S7IAN3_VIBFL/254-354      AC S7IAN3.1
#=GS Q084K2_SHEFN/220-315      AC Q084K2.1
#=GS A0A1S1MYI0_9GAMM/213-308  AC A0A1S1MYI0.1
#=GS A0A3D8M6P1_9ALTE/163-258  AC A0A3D8M6P1.1
#=GS A0A085GLE9_9GAMM/328-422  AC A0A085GLE9.1
#=GS A0A2S2E508_9ALTE/169-264  AC A0A2S2E508.1
#=GS A0A1T4VJ32_9GAMM/235-323  AC A0A1T4VJ32.1
#=GS A0A090SWV8_9VIBR/1-84     AC A0A090SWV8.1
#=GS A0A2N1D3B7_9ALTE/198-293  AC A0A2N1D3B7.1
#=GS A0A1G9A0B0_9GAMM/206-301  AC A0A1G9A0B0.1
#=GS A0A366W098_9GAMM/281-376  AC A0A366W098.1
#=GS C4K8V1_HAMD5/219-313      AC C4K8V1.1
#=GS A0A553FJT6_9GAMM/224-320  AC A0A553FJT6.1
#=GS Q6LP46_PHOPR/249-344      AC Q6LP46.1
#=GS A0A0K2BK37_9GAMM/1-39     AC A0A0K2BK37.1
#=GS A8FUE4_SHESH/219-314      AC A8FUE4.1
#=GS A0A432ZK28_9GAMM/215-310  AC A0A432ZK28.1
#=GS H3R889_PANSE/30-114       AC H3R889.1
#=GS A0A2X0WU30_9GAMM/221-307  AC A0A2X0WU30.1
#=GS Q12PE7_SHEDO/228-323      AC Q12PE7.1
#=GS U4K6U7_9VIBR/250-348      AC U4K6U7.1
#=GS A0A094IWF0_9GAMM/195-290  AC A0A094IWF0.1
#=GS A0A447M7Z0_SALBN/166-260  AC A0A447M7Z0.1
#=GS A0A1X0W9P5_9GAMM/37-128   AC A0A1X0W9P5.1
#=GS A0A094IR34_9GAMM/196-291  AC A0A094IR34.1
#=GS A0A2I5TAC4_SERS3/287-381  AC A0A2I5TAC4.1
#=GS A0A6I4LSD6_9ENTR/46-140   AC A0A6I4LSD6.1
#=GS J3TXQ2_9ENTR/171-265      AC J3TXQ2.1
#=GS A0A2A5T0E3_9GAMM/217-312  AC A0A2A5T0E3.1
#=GS A0A5P8YDT0_YERPE/291-385  AC A0A5P8YDT0.1
#=GS A0A250AVF4_9ENTR/37-131   AC A0A250AVF4.1
#=GS I4W9Z5_9GAMM/203-301      AC I4W9Z5.1
#=GS A0A090TAM6_9VIBR/239-337  AC A0A090TAM6.1
#=GS A0A377I147_HAEPH/319-415  AC A0A377I147.1
#=GS A0A1W6B0V4_9GAMM/336-430  AC A0A1W6B0V4.1
#=GS A0A0F4P1V2_9VIBR/21-112   AC A0A0F4P1V2.1
#=GS A0A291BBR0_9GAMM/219-314  AC A0A291BBR0.1
#=GS D0IBG0_GRIHO/245-340      AC D0IBG0.1
#=GS A0A071M617_9ENTR/35-128   AC A0A071M617.1
#=GS A0A075NUV8_9ALTE/162-257  AC A0A075NUV8.1
#=GS B1KIF7_SHEWM/209-304      AC B1KIF7.1
#=GS A0A0F4PJ01_9GAMM/211-306  AC A0A0F4PJ01.1
#=GS A0A4U1B5X8_9GAMM/214-310  AC A0A4U1B5X8.1
#=GS D3VAP6_XENNA/216-311      AC D3VAP6.1
#=GS E6KYY3_9PAST/270-365      AC E6KYY3.1
#=GS A0A1H3VW99_9GAMM/272-366  AC A0A1H3VW99.1
#=GS A0A432WAV6_9GAMM/193-288  AC A0A432WAV6.1
#=GS A0A1X1ES70_PANCY/321-415  AC A0A1X1ES70.1
#=GS A0A662ZHW9_9GAMM/302-393  AC A0A662ZHW9.1
#=GS A0A0A3YUY0_9GAMM/305-399  AC A0A0A3YUY0.1
#=GS A0A6I4VC61_9GAMM/225-319  AC A0A6I4VC61.1
#=GS H5V301_ATLHE/341-435      AC H5V301.1
#=GS A0A3N5Y3F4_9ALTE/158-253  AC A0A3N5Y3F4.1
#=GS A0A4R1NB23_9GAMM/340-434  AC A0A4R1NB23.1
#=GS A0A3R8YW81_9GAMM/346-440  AC A0A3R8YW81.1
#=GS A0A0J1HI92_9GAMM/256-351  AC A0A0J1HI92.1
#=GS A0A198FJ97_9GAMM/244-337  AC A0A198FJ97.1
#=GS A0A0C5WLG8_9GAMM/218-313  AC A0A0C5WLG8.1
#=GS A0A2S6VPR9_9GAMM/22-94    AC A0A2S6VPR9.1
#=GS A0A4R6VM02_9PAST/282-377  AC A0A4R6VM02.1
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