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Database: Pfam
Entry: TraA
LinkDB: TraA
Original site: TraA 
#=GF ID   TraA
#=GF AC   PF05513.11
#=GF DE   TraA
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_9521 (release 8.0)
#=GF GA   21.60 21.60;
#=GF TC   21.90 21.60;
#=GF NC   21.30 21.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12399504
#=GF RT   Functional analysis of TraA, the sex pheromone receptor encoded
#=GF RT   by pPD1, in a promoter region essential for the mating response
#=GF RT   in Enterococcus faecalis. 
#=GF RA   Horii T, Nagasawa H, Nakayama J; 
#=GF RL   J Bacteriol 2002;184:6343-6350.
#=GF DR   INTERPRO; IPR008873;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Conjugative transfer of a bacteriocin plasmid, pPD1, of
#=GF CC   Enterococcus faecalis is induced in response to a peptide sex
#=GF CC   pheromone, cPD1, secreted from plasmid-free recipient cells.
#=GF CC   cPD1 is taken up by a pPD1 donor cell and binds to an
#=GF CC   intracellular receptor, TraA. Once a recipient cell acquires
#=GF CC   pPD1, it starts to produce an inhibitor of cPD1, termed iPD1,
#=GF CC   which functions as a TraA antagonist and blocks self-induction
#=GF CC   in donor cells. TraA transduces the signal of cPD1 to the mating
#=GF CC   response [1].
#=GF SQ   36
#=GS W1E4R8_KLEPN/1-120        AC W1E4R8.1
#=GS A0A0L0UNB3_9BASI/58-180   AC A0A0L0UNB3.1
#=GS W1DGH1_KLEPN/1-105        AC W1DGH1.1
#=GS A0A098GA35_9GAMM/3-106    AC A0A098GA35.1
#=GS A0A2A2GWB8_9GAMM/3-119    AC A0A2A2GWB8.1
#=GS A0A0A3ZQC9_9GAMM/1-127    AC A0A0A3ZQC9.1
#=GS A6TIG0_KLEP7/1-100        AC A6TIG0.1
#=GS A0A0W0XSK6_9GAMM/1-113    AC A0A0W0XSK6.1
#=GS A0A0A8UXU8_LEGHA/3-106    AC A0A0A8UXU8.1
#=GS A0A085FZ24_9ENTR/1-116    AC A0A085FZ24.1
#=GS A0A071LQ45_9ENTR/27-147   AC A0A071LQ45.1
#=GS D4EA56_SEROD/1-119        AC D4EA56.1
#=GS H3RL68_PANSE/11-128       AC H3RL68.1
#=GS A0A0K2E1J3_PISSA/2-104    AC A0A0K2E1J3.1
#=GS A0A0C2IV57_THEKT/22-137   AC A0A0C2IV57.1
#=GS A0A0L0CC97_LUCCU/118-241  AC A0A0L0CC97.1
#=GS A0A0G3Q778_KLUIN/24-128   AC A0A0G3Q778.1
#=GS D8MK43_ERWBE/27-139       AC D8MK43.1
#=GS A0A0T9R1M4_9GAMM/1-116    AC A0A0T9R1M4.1
#=GS A0A0J8YF81_9BACT/4-114    AC A0A0J8YF81.1
#=GS G2GX05_9ENTR/2-84         AC G2GX05.1
#=GS H6SI81_SALEN/1-118        AC H6SI81.1
#=GS A0A0J8VLR7_9ENTR/10-127   AC A0A0J8VLR7.1
#=GS E6WNQ9_PANSA/16-129       AC E6WNQ9.1
#=GS A0A0M3EXR0_ENTCL/1-116    AC A0A0M3EXR0.1
#=GS B2VB05_ERWT9/2-104        AC B2VB05.1
#=GS H9L4B7_SALTY/1-118        AC H9L4B7.1
#=GS Q2NQ45_SODGM/22-63        AC Q2NQ45.1
#=GS E6WLT1_PANSA/19-129       AC E6WLT1.1
#=GS A0A0H3GYZ1_KLEPH/1-120    AC A0A0H3GYZ1.1
#=GS A0A0W0SZR8_9GAMM/11-102   AC A0A0W0SZR8.1
#=GS W3YD47_9GAMM/1-115        AC W3YD47.1
#=GS A0A2A2HMP4_9GAMM/3-117    AC A0A2A2HMP4.1
#=GS B6ESX3_ALISL/6-91         AC B6ESX3.1
#=GS A6TIT3_KLEP7/1-120        AC A6TIT3.1
#=GS A4WGS0_ENT38/5-116        AC A4WGS0.1
W1E4R8_KLEPN/1-120                   ..............................................MNAVLSVQGSAV.PEKTKPSFMSRVFNKKK...AL......K..AAKVALP..V.A..A..VA.AFFPDAA.MAT....T...TATDLMKSGDATVKGTFGKQSSVVKW.VV.LAEVVAGGIMYMMTKN.VKFLF...GFAIISTFITIGMSVA.........
A0A0L0UNB3_9BASI/58-180              aegkrisnerstfyvrqvpahlgavamakanlynpnvltmvgftlm------------.-----------------...--......-..-------..-.-..A..LAlMFMPS--.-TH....A...EAVDLFTKGRTNIKDTFGLSSTVVWI.LY.IIEGLGAVFTYTKTKN.LAVFG...GIAAVMVFVNVL----fgii.....
W1DGH1_KLEPN/1-105                   ..............................................MNAVLSVQGSAV.PEKTKPSFMSRVFNKKK...AL......K..AAKVALP..V.A..A..VA.AFFPDAA.MAT....T...TATDLMKSGDATVKGTFGKQSSVVKW.VV.LAEVVAGGIMYMMTKK.-----...----------------revpvw...
A0A098GA35_9GAMM/3-106               ........vstvirkssiklhefiqwsvpllvfswvvvlcltntgy------------.-----------------...--......-..-------..-.-..-..--.-------.---....A...EGQNYLSAMKGDVSATFGKNSDLPGY.LY.AGETLVAGVTWMKTKS.PWVFV...GLPLLMIFTHWGLSY-v........
A0A2A2GWB8_9GAMM/3-119               .............................gkvisclknpftvgava------------.--------------IFK...VL......K..QQKSLLT..M.TffG..IL.MLFPAMQ.VYAddtpV...VAKDLFSGGKEVVKSTFGKGSTVVWI.LY.VLEILAAIFAYVKTKN.LAVFG...GIAAVIVFVNVV----fgli.....
A0A0A3ZQC9_9GAMM/1-127               ......................................madisvin-------QGADVvCQGNKKGLLSRMVSAVK...AVpsmannR..TAKALFK..Y.V..A..VP.LALFLAA.RGM....A...HAEDLTAAGKADANDTFGADSTMMYY.FM.LAEVVLVFLLYLKSHN.P---A...TFLLIPVFIVVT----kiifai...
A6TIG0_KLEP7/1-100                   ..............................................------------.--------MSRVFNKKK...AL......K..AAKVALP..V.A..A..VA.AFFPDAA.MAT....T...TATDLMKSGDATVKGTFGKQSSVVKW.VV.LAEVVAGGIMYMMTKN.VKFLF...GFAIISTFITIGMSVA.........
A0A0W0XSK6_9GAMM/1-113               .........................mkkkqfmtinamvreksiqlh------------.-----------------...--......E..FLKWSMP..V.L..V..FC.WFLMLCF.TST....GhaeAGQNYLSGMKSDVSATFGKNSDLPGY.LY.GAETLVAGFTWMKSKS.PWVFV...GLPLLIIFTHWGLS--yv.......
A0A0A8UXU8_LEGHA/3-106               ............vsavirkssiklyefmrwslpllvlswlivlclt------------.-----------------...--......-..-------..-.-..-..--.------N.IGY....A...EGQNYLSGVKSDVSATFGKNSDLPGY.LY.AGETLVAGVTWMKTKS.PWVFV...GLPLLMIFTHWGLSY-v........
A0A085FZ24_9ENTR/1-116               ..............................mftqgyalnvekgwav------------.--------AS-LFRKAR...EN......R..QLKKLIK..N.G..G..LV.LISLMVAhPVL....A...SGTDLLASQQATVSSTFGSGSSIVKW.FY.IAEIIIALFTYIKVRS.PLVFL...GLVICIIFTRIAFAI-a........
A0A071LQ45_9ENTR/27-147              ...............................iamtlsgeiaanddh------------.--TTASSVLSRLQHKRT...QY......K..EALKTVA..A.F..G..GV.LALMAAM.MHP....A...LATDLLSSQDSSVTATFGHGSSIEKY.FY.YAEIFIAIFTYIKSRS.PLAFV...GLVIMILFTRIGFQI-a........
D4EA56_SEROD/1-119                   ..............................................MNASLSAQGPAV.AQSQG-FSLSKMFSRQR...VV......N..FLKFLLP..M.A..V..LA.VFFPQVA.LAA....G...AGADMLKPGDATVKATAGSGSTMYKW.II.LGEVVAGLVLYVLTHS.FKFLF...GFIILSIIGNVGMKVA.........
H3RL68_PANSE/11-128                  .................tglsrqgerkgllfrmvsavksvptllnn------------.-----------------...--......K..TAKALFK..Y.V..A..VP.LAIWLAA.RGM....A...HADDLTKAGKQDAEDTFGADSTMMYY.FM.LAEVVLVFLLYLRSHN.P---A...TFLLIPVFIVVT----kiifaii..
A0A0K2E1J3_PISSA/2-104               .......................iktkqialktyerlieyapymlg------------.-----------------...--......-..-------..-.A..M..IL.YLIASSP.LFA....A...TGTDYLSGIKDSTASSFGEGSTFEHL.LY.LGEGIAGVYGYIKTKN.IMILG...GLIVVMIFTHFGFAM-a........
A0A0C2IV57_THEKT/22-137              ..............................cqkpisgkylstkkmv------------.------KGFVRTACKKG...YQ......H..RANVTLV..AlA..M..LC.FALPHLA.---....-...GATDLLAAQKQDAKDTFGHGST-VEWgFY.IGEIIISIGGYIKTRNpMLFVG...GLAFLIV---------itrtffala
A0A0L0CC97_LUCCU/118-241             ............seisvgnapsvvtkkagvfarakasikrsvavln------------.-----------------...-T......K..TARTVFR..C.V..GmpLA.VFLA--S.RGV....A...QADDLMTAGRKDAEETFGEGSTMMYY.IM.LAEVVLVFLLYLRNHNpATFLFi.pVFFVVT----------tvifail..
A0A0G3Q778_KLUIN/24-128              ....................gasslfigmlrgafsliyrhrinlll------------.-----------------...--......-..-----LC..L.A..V..VF.IALPHL-.---....G...HAEDLLSGQKQDAKDTFGHGST-VEWgLY.IAEVLISAAAYMKTRNpMLFVG...GLAFLI----------vitrsffal
D8MK43_ERWBE/27-139                  ............gniishikksiysfsiprlksrlrhspeaqrnla------------.-----------------...--......-..--LFALM..L.A..V..V-.-IFPHIA.---....-...GAEDLLKSQKADANDTFGHG-STVEW.VLyIAEIIVSVVGYIKTRN.PMVFA...GLVILI----------litraffsl
A0A0T9R1M4_9GAMM/1-116               ........................................mseisi------MNGVDI.KPAKK-GLLTRVMAAAN...N-......K..SAKALVKylA.A..P..LA.VWM--CA.QGF....A...RAEDLAAAGRTDVEDTFGSDSTMMYY.FM.VAEVVLVFLLYLKTHN.P---A...TFLLIPVFIVVT----kvifs....
A0A0J8YF81_9BACT/4-114               ....................................istlnavpas------------.-------AVKKKISKVG...LL......K..SLKLALP..V.A..A..VA.TFFPETV.MAS....S...AGKDLMASGNDTVKSTFGSGSSVVKW.VI.LAEVLVGAVMYMTTKN.LKFLA...GFAILSVFVAIGMSVA.........
G2GX05_9ENTR/2-84                    ...............................ivlilisimallgit------------.-----------------...--......-..-------..-.-..-..--.-------.-ST....V...QAVDLMAGGKVTVTDTFGASSAIAKW.II.LAEVIVGIITFIKTKN.VFMLF...GIAVVIVFTTIGFSL-t........
H6SI81_SALEN/1-118                   ..............................................MSAILSVQGASA.PVKKK-SFFS-EFTRLN...LL......K..LARAVIP..A.A..V..LM.FFFPQLA.MAA....G...GSQDLMASGNGTVKATFGKDSSAVKW.VI.LAEVLVGAVMYMMTKN.VKFLA...GFAIISVFIAVGMAVV.........
A0A0J8VLR7_9ENTR/10-127              ..................arkgwavaslfrkaqenvisvksqikqr------------.----------------K...EL......KtfLARGGLF..A.L..L..LL.STHPSF-.-AA....G...--GDLLASQDSTVTSTFGHGSSLEKY.FY.FGEIIMALFTYIRARS.PLVFV...GLIIVIIFTRVGFAL-a........
E6WNQ9_PANSA/16-129                  ...........................eacpafrtaapsgfigtly------------.----------RSFSLLW...RH......R..VNVLLIA..L.A..V..LF.FALPHLV.---....-...RAEDLLSSQKQDAKDTFGHGSTI-EWgLY.IAEVIISIGAYIKTRN.PMLFVgglGFLIVV----------trvlfsla.
A0A0M3EXR0_ENTCL/1-116               ............................mstksnalkakkgwavas------------.-----------LFRKARenvAL.....rN..VAKC-GG..L.A..L..IS.LMFAHSA.MAA....G...--TDLLSSQNTTVNATFGSGSSIVKW.FY.LAEILFGVFIYIKTRS.PLTFI...GIPILIIATRVGFAI-a........
B2VB05_ERWT9/2-104                   ........................................kralks------------.-------ILN--FSRAN...KK......K..LS--IVM..A.A..V..TV.CMLPEIA.FSA....D...SSTDLLQAQQATINSTFGHGSSLEKY.FY.IAEVFMSLIAYFRART.PMVFI...GLIMVIIFTRIAF---gii......
H9L4B7_SALTY/1-118                   ..............................................MSAILSVQGASA.PVKKK-SFLS-TFTRLN...LL......K..LARAVIP..A.A..V..LI.FFFPQLA.MAA....G...GSQDLMASGNGTVKATFGKDSSAVKW.VI.LAEVLVGAVMYMMTKN.VKFLA...GFAIISVFIAVGMAVV.........
Q2NQ45_SODGM/22-63                   ........................................tsglsw------------.-----------------...--......-..-------..-.-..-..--.-------.---....-...--------------------------.--.-GEVLAGMVLYVLTHS.FKFLF...GFIILSIIGNVGMKVA.........
E6WLT1_PANSA/19-129                  ..............................psrrarvpsgiigivl------------.----------RAFSVIR...RH......R..VNVLLIA..L.A..V..LC.FALPHLV.R--....-...-AEDLLSSQKQDAKDTFGHGSTI-EWgLY.IAEVIISIGAYIKTRN.PMLFVgglGFLIVV----------trvlfsla.
A0A0H3GYZ1_KLEPH/1-120               ..............................................MNAVLSVQGSAV.SEKTKPSFMSRVFNKKK...AL......K..VAKVALP..V.A..A..VA.AFFPDAA.MAT....T...TATDLMKSGDATVKGTFGKQSSVVKW.VV.LAEVVAGGIMYMMTKN.VKFLF...GFAIISTFITIGMSVA.........
A0A0W0SZR8_9GAMM/11-102              ...........................sikgylyarqllpflmigl------------.-----------------...--......-..-------..-.-..A..LL.CLMPDTC.FAA....E...N---RLSGLKEEVKATFGADSDLPYF.LL.LAEGLAGAYAYIKTKN.IAVLA...GVPVLMVFT-------hwal.....
W3YD47_9GAMM/1-115                   .......................................msqiaid-----------S.PVTKRKGIFSRAWSALN...T-......K..TAKSLYK..Y.V..A..AP.LVLWMAA.RGF....A...QAADLAKEGVQDAGDTFGSGSSVMYY.IM.IAEAILIFLAFMKTQN.PALLLl.iPVFIVGTKI-------vfgli....
A0A2A2HMP4_9GAMM/3-117               ..............gkvtsclknpftagavaifkvlkqqqslftlm------------.-----------------...--......-..-------..F.F..G..LL.MFIPAMQ.VYA....Dp.pTTGDLFSGGKDVVKSTFGKGSTVVWI.LY.VLEILAAIFAYVKTKN.LAVFG...GIAAVIVFVNVV----fgli.....
B6ESX3_ALISL/6-91                    ............................itprnllltgtsvllatq------------.-----------------...--......-..-------..-.-..-..--.-------.--P....A...LAADMFASGKTAIKDTVGTDSTVETA.IL.SAGAVGAALTGFITKNwIGAIG...GFAVGMIFWSV-----vapmv....
A6TIT3_KLEP7/1-120                   ..............................................MNAVLSVQGSAV.PEKTKPSFLSRVFNKKK...AL......K..VAKVALP..V.A..A..VA.AFFPDAA.MAT....T...TATDLMKSGDATVKGTFGKQSSVVKW.VV.LAEVVAGGIMYMMTKN.VKFLF...GFAIISTFITIGMSVA.........
A4WGS0_ENT38/5-116                   dnalnvvkgwavaslfrtalenrqmkkflkngglilislmvahpvl------------.-----------------...--......-..-------..-.-..-..--.-------.---....A...AGTDLLAPQQATVNSTFGSGSSLIKW.FY.IAEIVMGLFIYIKARS.PLVFV...GIVGCIIFTRVAFS--ia.......
#=GC seq_cons                        ..........................................hhh..........................................c....hhhh...h.s..s..lh.hhhsths.hsh....s...tupDLhuutcssVpuTFGcsSolhca.lh.lAEllhuhhhYh+T+N.shhhs...GhsllhlFhtls....h........
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