GenomeNet

Database: Pfam
Entry: Transformer
LinkDB: Transformer
Original site: Transformer 
#=GF ID   Transformer
#=GF AC   PF06495.11
#=GF DE   Fruit fly transformer protein
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_13780 (release 10.0)
#=GF GA   26.50 26.50;
#=GF TC   26.60 26.50;
#=GF NC   26.40 26.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8013913
#=GF RT   Molecular population genetics of sex determination genes: the
#=GF RT   transformer gene of Drosophila melanogaster. 
#=GF RA   Walthour CS, Schaeffer SW; 
#=GF RL   Genetics 1994;136:1367-1372.
#=GF DR   INTERPRO; IPR010519;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of transformer proteins from several
#=GF CC   Drosophila species and also from Ceratitis capitata
#=GF CC   (Mediterranean fruit fly). The transformer locus (tra) produces
#=GF CC   an RNA processing protein that alternatively splices the
#=GF CC   doublesex pre-mRNA in the sex determination hierarchy of
#=GF CC   Drosophila melanogaster [1].
#=GF SQ   34
#=GS A0A1L8FGP1_XENLA/6-122    AC A0A1L8FGP1.1
#=GS A0A0V0YF79_TRIPS/12-150   AC A0A0V0YF79.1
#=GS A0A1L3KIY5_9VIRU/2-147    AC A0A1L3KIY5.1
#=GS W5L948_ASTMX/5-128        AC W5L948.1
#=GS B3M4G4_DROAN/3-179        AC B3M4G4.2
#=GS B4LB81_DROVI/1-189        AC B4LB81.2
#=GS S8BSI1_DACHA/12-142       AC S8BSI1.1
#=GS A0A1L8FMU9_XENLA/6-121    AC A0A1L8FMU9.1
#=GS A0A1I8NZ16_STOCA/111-245  AC A0A1I8NZ16.1
#=GS W2PYB1_PHYPN/65-216       AC W2PYB1.1
#=GS G7YVU8_CLOSI/44-183       AC G7YVU8.1
#=GS B4L9E2_DROMO/1-197        AC B4L9E2.1
#=GS W2GET0_PHYPR/63-214       AC W2GET0.1
#=GS F1QVD2_DANRE/5-131        AC F1QVD2.1
#=GS B5DR46_DROPS/1-187        AC B5DR46.2
#=GS H2Z1Z9_CIOSA/1-132        AC H2Z1Z9.1
#=GS V9ERF1_PHYPR/63-214       AC V9ERF1.1
#=GS TRSF_DROME/3-187          AC P11596.1
#=GS A0A1L8FGS2_XENLA/6-122    AC A0A1L8FGS2.1
#=GS A0A1A9UGC0_GLOAU/53-219   AC A0A1A9UGC0.1
#=GS A0A1U7YQ33_NICSY/115-264  AC A0A1U7YQ33.1
#=GS A0A1S3YZ20_TOBAC/116-264  AC A0A1S3YZ20.1
#=GS H0W3M0_CAVPO/330-452      AC H0W3M0.2
#=GS A0A074ZGI3_9TREM/102-241  AC A0A074ZGI3.1
#=GS Q28EQ0_XENTR/6-122        AC Q28EQ0.1
#=GS B4J1D8_DROGR/261-443      AC B4J1D8.1
#=GS A0A182YCS6_ANOST/44-174   AC A0A182YCS6.1
#=GS A0A1W4UGH0_DROFC/1-178    AC A0A1W4UGH0.1
#=GS E7F8Y4_DANRE/5-131        AC E7F8Y4.3
#=GS B4H201_DROPE/1-143        AC B4H201.1
#=GS B4QMV6_DROSI/1-172        AC B4QMV6.1
#=GS A0A0R3SJW2_HYMDI/34-170   AC A0A0R3SJW2.1
#=GS A0A1A9W460_9MUSC/111-295  AC A0A1A9W460.1
#=GS A0A0W8E0Q3_PHYNI/144-295  AC A0A0W8E0Q3.1
A0A1L8FGP1_XENLA/6-122               ................deferqlnenkq------------.--.........................-------....---------------------.----E----RDKEN.....RHRKRSR..SRSK.......---SKER.KRRSRSKE.R.R---A.........RE.QRSG.SR.....DRRRRSRSPRH....--E...KK..KKIRKYWD...IPP..PGF.EH-..------...------.----.--...----.-....---...----..---------..-----.--.-------itplqykamqaagqipatallptmtpdglavtptp...........................
A0A0V0YF79_TRIPS/12-150              ...................ddevvsnnh------------.--.........................-------....---------------------.-------SANNRGS.....RTRSRSS..TRTP.......SRSRSFT.RSRSRTRS.P.TRSRS.........RD.RRRS.R-.....NKRSRSSSRDR...rRRR...TP..EAVLV---...---..---.---..------...------.----.--...----.-....---...----..---------..-----.--.-------tegidmgvdeanlahlcqiesenpptsrclgvfglslytterdlhqlfskygkvddiqlvyd
A0A1L3KIY5_9VIRU/2-147               ......................nngvkk------------.--.........................-------....---------------------.MLNNKRDVNANNTR.....QSRSQSR..GRSK.......SRANGNQ.KNKQRGNS.R.RRSNS.........RN.RSKS.RS.....NSRGRSGSKSR....VRP...YG..TYKKVHVPqfgVNS..HKH.VFT..ISNQTF...EIQINV.KQGNpMQ...YTTT.D....YLI..mALYF..AVYARPD--..-----.--.-------grslqnkviks...................................................
W5L948_ASTMX/5-128                   ....................deferqlt------------.--.........................-------....---------------------.-----ENKQADRDK.....ENKHHRR..SSSR.......SR-SRDR.KRRSRDRE.R.RGSRE.........RG.HADS.KD.....RRHRRSRSPHR....EKK...KI..KV-KKYWD...VPP..PGF.EHI..------...------.----.--...----.-....---...----..---------..-----.--.-------tpmqykamqaagqipatallptmtpeglavtptpvp..........................
B3M4G4_DROAN/3-179                   ............................MDADSS-RGHKD.SHgsrsrrkrdsyerdnsrerkrerdrERQREDE...kKVPYFADAGRERDRVKNSRT-.------------NR.....RSRTRSR..SRSS.......ERRRWHR.R-RSSSDS.R.NHYRS.........RS.PN--.--.....-----RRSMRK....DTP...PP..KIINYYVQ...VPA..HEFnGYG..YGMYGP...YGMVPP.--PR.YG...YQRL.P....RP-...SHF-..-----PSAH..LMYRHrPP.FSRTPRF..............................................................
B4LB81_DROVI/1-189                   ............................MDADSSSRSPRD.TR.........................RRSRQRE....KMPYFADEVRERDRVRNLRKL.KTTQKRTPTPPRERrsrheRPRSRSR..THSP.......EQSRCQR.R-RSRSYV.R.HRSVS.........RQ.KTSSsSC.....SRRRRSRSRSRs.rgRSR...TP..RIITVPVP...VPA..AEY.SYA..YGWPPP...RPHFNP.MYGA.LP...FGMQ.P....RPL...NPYF..GSYARPP-P..FRYRA.GP.FRPHPRY..............................................................
S8BSI1_DACHA/12-142                  ..................ddayaaasaa------------.--.........................-------....---------------------.-----------KKG.....KLKLKSK..RRSH.......RHNDGHR.RHRSRTRS.R.SRSRT.........RS.RSAS.PI.....SLNRKKRKQPTv..tETD...DP..SLY-DDVY...LPG..QNS.-FK..YKDPEAafqESLFEA.M---.--...----.-....---...----..---------..-----.--.-------adddgaaywegvygqpihnysrprvenek.................................
A0A1L8FMU9_XENLA/6-121               ...................eferqlnen------------.--.........................-------....---------------------.--------KQERDK.....ENRHKKR..SHSR.......SRSR-ER.KRRSRSRE.R.R---A.........RE.QRSG.SK.....DRRRRSRSPRN....--E...KK..KKIRKYWD...IPP..PGF.EH-..------...------.----.--...----.-....---...----..---------..-----.--.-------itplqykamqaagqipatallptmtpdglavtptp...........................
A0A1I8NZ16_STOCA/111-245             keshktsekkgdvrgskanddphkkkdl------------.-Phe.....................lqSESVKKH....KVPYFSDPVRERDRLRRLYGSpAKQKSRSHTPPHSR.....RQASTGRylHDSP.......TRRRSRS.RHKHRSRS.S.QRIRS.........RS.RGHS.S-.....-YRGHSPSRHS....---...--..--------...---..---.---..------...------.----.--...----.-....---...----..---------..-----.--.-------syrdhfpy......................................................
W2PYB1_PHYPN/65-216                  .....................npadpad------------.--.........................-------....------------DRHRSSRR-.-SHRSRSGSSHRRD.....RSRSRER..RSSR.......HRSSRDR.RSRSRERE.R.RRSRD.........HS.ERRS.S-.....-RRSRSRSSTR....IVR...RR..KKSNFDVR...PPGvtEEN.AAA..YAAQAI..lQQNMAA.LSGS.VGpasFGAP.P....NPT...-P--..---------..-----.--.-------tgnvpaapmyshshagpgyg..........................................
G7YVU8_CLOSI/44-183                  ................dinsteyldrkd------------.--.........................-------....---------------------.-----R-SPRHRKR.....DSSSEDR..GRDR.......KRDKKRS.RSRSRSRE.RrRHSRD.........RH.RDRS.RE.....RRSKHRHSRHR....-SE...TP..PLIYKYWD...VPP..PGF.EHV..TPAQYK...AMQASG.QIPV.NV...YAAG.Q....IPM...PAH-..AP-------..-----.--.-------napltlttnipfagsa..............................................
B4L9E2_DROMO/1-197                   ............................MDADSSSRSPRD.TR.........................RRTRPKEkekeKVPYFADEARERDRVRNLRLR.KTSITRPTTPPRGR.....PRRARSR..SYSA.......ERNCCHR.RRRSRSYE.R.RHSSN.........RY.KSAT.ALaakpnRRRSRSRSRSR...sRSR...TP..RIITVPVP...VPA..ADY.PYA..YAWPPPp.qRPHFNP.MYGA.VP...YGLP.P....RPVypgHPYF..APYPRPRPT..FPYRA.AP.FRPHPRF..............................................................
W2GET0_PHYPR/63-214                  .....................npadpad------------.--.........................-------....------------DRHRSSRR-.-SHRSRSGSSHRRD.....RSRSRER..RSSR.......HRSSRDR.RSRSRERE.R.RRSRD.........HS.ERRS.S-.....-RRSRSRSSTR....IVR...RR..KKSNFDVR...PPGvtEEN.AAA..YAAQAI..lQQNMAA.LSGS.VGpasFGAP.P....NPT...-P--..---------..-----.--.-------tgnvpaapmyshshagpgyg..........................................
F1QVD2_DANRE/5-131                   ...................deferqlte------------.--.........................-------....---------------------.NKQADRDKENKHH-.....-RRSGSR..SRSR.......DRD-RKR.RSRDRDRE.R.RGSRD.........RH.GDSK.D-.....RRHRRSRSPHR....EKK...KI..KV-KKYWD...VPP..PGF.EHI..------...------.----.--...----.-....---...----..---------..-----.--.-------tpmqykamqaagqipatallptmtpeglavtptpvp..........................
B5DR46_DROPS/1-187                   ............................MDADSSVASHRD.SHrsrtrrdv........hvrdqgrerERVREQK....TVPYFADPVRERDRVKNVRPK.SPPST----GKRFR.....RTRSRSR..--SS.......DRRRYRR.RT------.-.-----.........--.RSRS.S-.....ERRHRNRSPRR....RTP...PP..RIITVPVP...VPA..HEF.AYG..YGWPAPh.pAHQFNG.IYGP.LA...YPPR.PrfgyRPM...RPSFqaAPYSRPYAH..HEYRHrHP.FNPQSRF..............................................................
H2Z1Z9_CIOSA/1-132                   .....................emksree------------.--.........................-------....---------------------.--------KKDRDRg...sSGRHRDR..KRSR.......DR---DR.KKRSRSRS.R.G---K.........RH.RSRS.R-.....DRKRKSRSKER....TER...KP..KKAYKYWD...VPP..IGY.EHV..TP----...-LQYKA.MQ--.--...----.-....---...----..---------..-----.--.-------aagqiplmaatqplnmaenamqvcvlhtvpsiyyfsnpimpm....................
V9ERF1_PHYPR/63-214                  .....................npadpad------------.--.........................-------....------------DRHRSSRR-.-SHRSRSGSSHRRD.....RSRSRER..RSSR.......HRSSRDR.RSRSRERE.R.RRSRD.........HS.ERRS.S-.....-RRSRSRSSTR....IVR...RR..KKSNFDVR...PPGvtEEN.AAA..YAAQAI..lQQNMAA.LSGS.VGpasFGAP.P....NPT...-P--..---------..-----.--.-------tgnvpaapmyshshagpgyg..........................................
TRSF_DROME/3-187                     ............................MDADSSGTQHRD.SRgsrsrsrre.......reyhgrsseRDSRKKE...hKIPYFADEVREQDRLRRLRQR.AHQSTR--------.....RTRSRSR..SQSS.......IRESRHR.RHRQRSRS.R.NRSRSrsserkrrqRS.RSRS.S-.....ERRRRQRSPHR....YNP...PP..KIINYYVQ...VPP..QDF.---..YG----...---MSG.MQQS.FG...YQRL.P....RP-...PPF-..-----PPAP..YRYRQrPP.FIGVPRF..............................................................
A0A1L8FGS2_XENLA/6-122               ................deferqlnenkq------------.--.........................-------....---------------------.----E----RDKEN.....RHRKRSR..SRSK.......---SKER.KRRSRSKE.R.R---A.........RE.QRSG.SR.....DRRRRSRSPRH....--E...KK..KKIRKYWD...IPP..PGF.EH-..------...------.----.--...----.-....---...----..---------..-----.--.-------itplqykamqaagqipatallptmtpdglavtptp...........................
A0A1A9UGC0_GLOAU/53-219              ...............krndrhlrhqalk----------RE.TKv.......................qSEATFRS....KLPYYRDAERECDRLKRLYGN.RDEKYSDLRRSRKE.....DFRKQKP..TESF.......SKRANDRnGHRSRRTD.R.GKRNY.........KP.KREK.S-.....-PRRQTRSVAR....KSP...QSsgETKIVYVP...IPI..LTY.PYQ..YWRP--...------.----.--...----.-....---...----..---------..-----.--.-------nfydgyfrsnwtrpnqnfhqqtfchnkm..................................
A0A1U7YQ33_NICSY/115-264             ..................egreywqkdy------------.--.........................-------....----------DRDRDERHRHR.SKSYER----EREE.....GHRHRSK..SYDK.......DREERDR.-HRSKSYD.K.DREERr......ghRS.HSRG.KS.....GHRSRSRSRSR...sRSK...SK..RISGFDMA...PPT..S--.---..------...------.----.--...----.-....---...----..---------..-----.--.-------allpgapavtgqlpatapaipgifpnmfplasaqlgaipvmpvqamtq..............
A0A1S3YZ20_TOBAC/116-264             ...................greywqkdy------------.--.........................-------....----------DRDRDERYRHR.SKSYER----EREE.....GHRHRSK..SYDK.......DREERDR.-HRSKSYD.K.DREERr......ghRS.HSRG.KS.....GHRSRSRSRSR...sRSK...SK..RISGFDMA...PPT..S--.---..------...------.----.--...----.-....---...----..---------..-----.--.-------allpgapavtgqlpatapaipgifpnmfplasaqlgaipvmpvqamtq..............
H0W3M0_CAVPO/330-452                 ..................vqeevfeqea------------.--.........................-------....---------------------.-----------KKV.....AVRSRSR..THSR.......SRSRRKH.RKRSRSRS.R.ERKRK.........SS.RSYS.S-.....ERRAREREKER...qKKG...LP..PIRSKT--...---..---.---..------...------.----.--...----.-....---...----..---------..-----.--.-------lsvcsttlwvgqvdkkatqqdltnlfeefgqiesinmipprgcayvcm..............
A0A074ZGI3_9TREM/102-241             ................dinsteyldrkd------------.--.........................-------....---------------------.-----R-SPRHRKR.....DSSSEDR..GRDR.......KRDKKRS.RSRSRSRE.RrRHSRD.........RH.RDRS.RE.....RRSKHRHSRHR....-SE...TP..PLIYKYWD...VPP..PGF.EHV..TPAQYK...AMQASG.QIPV.NV...YAAG.Q....IPM...PAH-..AP-------..-----.--.-------napltlttnipfagsa..............................................
Q28EQ0_XENTR/6-122                   ...................eferqlnen------------.--.........................-------....---------------------.--------KQERDK.....ENRHRKR..SHSR.......SRS-RDR.KRRSRSRD.R.R---G.........RE.QRSG.SR.....DRRRRSRSPRH....--E...KK..KKIRKYWD...VPP..PGF.EHI..------...------.----.--...----.-....---...----..---------..-----.--.-------tpmqykamqaagqipatallptmtpdglavtptpv...........................
B4J1D8_DROGR/261-443                 ......................tgklmr--------RPRErER.........................AKEREKE....KLPYFTDVGRERDRTRNLRQH.RTERSPTPPPPPAR.....RQRLRSR..SHSP.......QTSNRQR.R-RSRSAE.R.SQRNS.........RNmRHAS.SY.....THRRRSRSRSR....-SR...TP..RIITVPVP...VPA..TGY.PYA..YGWP-R...QPHFNA.MFAP.MP...FAMHpP....RPL...NPYF..APYPRAPPPpsFRYRF.PPaIRPHARY..............................................................
A0A182YCS6_ANOST/44-174              ..deiqpddtdgnkqpnadveakinspg------------.--.........................-------....---------------------.--------------.....GMRSRSG..SRNS.......HTSQQDQ.RRRDRSGS.Q.V-SET.........RS.RKSR.STs...rQSRRRSRSQAR....SSSsysSA..RPYTFPVA...VPI..R-F.TIS..FT----...------.----.--...----.-....---...----..---------..-----.--.-------vpitlplsfpvpfaitvsitltltfrf...................................
A0A1W4UGH0_DROFC/1-178               ............................MDADSSGSVHRD.FHesrsrsgr........erenhgrlrERERKREe..pKVPYFADVARERDRVRRLRQR.SSRSPR-------R.....TRRSRSR..SLSY.......ERESRHR.RHGQRSRS.R.N----.........RS.RSRS.S-.....ERRHRERSPRR....YNP...PP..KIINYYVQ...VPA..QDF.YGM..YG----...AYAMG-.PPPR.FG...YQRP.P....RP-...PPF-..-----QPAS..YRFRHrPP.FLGAPRF..............................................................
E7F8Y4_DANRE/5-131                   ...................deferqlte------------.--.........................-------....---------------------.NKQADRDKENKHH-.....-RRSGSR..SRSR.......DRD-RKR.RSRDRDRE.R.RGSRD.........RH.GDSK.D-.....RRHRRSRSPHR....EKK...KI..KV-KKYWD...VPP..PGF.EHI..------...------.----.--...----.-....---...----..---------..-----.--.-------tpmqykamqaagqipatallptmtpeglavtptpvp..........................
B4H201_DROPE/1-143                   ............................MDADSSVASHRD.SHrsrtrrdv........hvrdqggerERVREQK....TVPYFADPVRERDRVKNVRPK.SPPST----GKRCR.....RTRSRSR..--SS.......DRRRYRR.RT------.-.-----.........--.RSRS.S-.....ERRHRNRSPRR....RTP...PP..RIITVPVP...VPA..HEF.AYG..YVSSIP...ISRF--.----.--...----.-....---...----..---------..-----.--.-------illkfafc......................................................
B4QMV6_DROSI/1-172                   ............................MDADSSGTEHRD.SRgsrsrswre.......rehhgrtseRDSRKKE...hKIPYFADEVREQDRIRRLRQR.AHQSTR--------.....RTRSRSR..SQSS.......DRGSRHR.RHRQRSRS.R.N----.........RS.RSRS.S-.....ERRRRQRSPHR....YNP...PP..KIINYYVQ...VPP..QDF.---..YG----...---MSG.MQQS.FG...YQRL.P....RP-...PPF-..-----PPAP..FRYRQrQP.FMGAPRF..............................................................
A0A0R3SJW2_HYMDI/34-170              .................taddvlsrhes------------.--.........................-------....---------------------.-------------E.....RDGGRHR..NGSD.......ERRSKDR.D-RRRDRH.R.SHSGSrg....hrrRS.RSRS.HD.....RHRRHHRSRDR...sESP...LK..KIVYKYWD...VPP..PGF.EHM..T---PQ...QYKALQ.ASGQ.IP...VNVY.A....AGQ...VPM-..-P-------..-----.--.-------astpnapltlntnipfagsa..........................................
A0A1A9W460_9MUSC/111-295             ..........dntptsseeskstsssfi------------.--.........................---HSRI...sKVPYFRDEIREQERLRHLYEK.EQHKSHSKSRNRYK....qRYRSPTR..YHSTctsrrskNKDNKYR.KSRSRTRStR.RRNHS.........RS.NREY.GS.....PRGREHKTPNIsnkdAQL...TS..RYITIPVA...LPP..ESMfPYAgfHNFPPP...-THYSPyTVMP.LM...TQRL.R....RPM...P---..---------..-----.--.-------rrafsmthetm...................................................
A0A0W8E0Q3_PHYNI/144-295             .....................npadpad------------.--.........................-------....------------DRHRSSRR-.-SHRSRSGSSHRRD.....RSRSRER..RSSR.......HRSSRDR.RSRSRERE.R.RRSRD.........HS.ERRS.S-.....-RRSRSRSSTR....IVR...RR..KKSNFDVR...PPGvtEEN.AAA..YAAQAI..lQQNMAA.LSGS.VGpasFGAP.P....NPT...-P--..---------..-----.--.-------tgnvpaapmyshshagpgyg..........................................
#=GC seq_cons                        ........................p.tt...................................................................................p+pc.....cpRoRoR..spSp.......cRpp+cR.RpRSRoRp.R.pppps.........Rs.+scS.u......pRR+RSRS.pR.....sc...p...+hhph.hs...lPs...ta..ah..h..........................................................................h....hhh..s...................................................
//
DBGET integrated database retrieval system