GenomeNet

Database: Pfam
Entry: Tropomyosin_1
LinkDB: Tropomyosin_1
Original site: Tropomyosin_1 
#=GF ID   Tropomyosin_1
#=GF AC   PF12718.9
#=GF DE   Tropomyosin like
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   manual
#=GF GA   34.20 34.20;
#=GF TC   34.20 34.20;
#=GF NC   34.10 34.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF WK   Tropomyosin
#=GF CL   CL0452
#=GF RN   [1]
#=GF RM   7844152
#=GF RT   Tropomyosin is essential in yeast, yet the TPM1 and TPM2
#=GF RT   products perform distinct functions.
#=GF RA   Drees B, Brown C, Barrell BG, Bretscher A;
#=GF RL   J Cell Biol. 1995;128:383-392.
#=GF RN   [2]
#=GF RM   9819304
#=GF RT   Identification and molecular characterization of Charybdis
#=GF RT   feriatus tropomyosin, the major crab allergen.
#=GF RA   Leung PS, Chen YC, Gershwin ME, Wong SH, Kwan HS, Chu KH;
#=GF RL   J Allergy Clin Immunol. 1998;102:847-852.
#=GF RN   [3]
#=GF RM   12740526
#=GF RT   Cloning and characterisation of two IgE-binding proteins,
#=GF RT   homologous to tropomyosin and alpha-tubulin, from the mite
#=GF RT   Lepidoglyphus destructor.
#=GF RA   Saarne T, Kaiser L, Rasool O, Huecas S, van Hage-Hamsten M,
#=GF RA   Gafvelin G;
#=GF RL   Int Arch Allergy Immunol. 2003;130:258-265.
#=GF DR   INTERPRO; IPR000533;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   This family is a set of eukaryotic tropomyosins. Within the
#=GF CC   yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate
#=GF CC   that Tpm2p spans four actin monomers along a filament, whereas
#=GF CC   Tpm1p spans five.  Despite its shorter length, Tpm2p can compete
#=GF CC   with Tpm1p for binding to F-actin. Over-expression of Tpm2p in
#=GF CC   vivo alters the axial budding of haploids to a bipolar pattern,
#=GF CC   and this can be partially suppressed by co-over-expression of
#=GF CC   Tpm1p. This suggests distinct functions for the two
#=GF CC   tropomyosins, and indicates that the ratio between them is
#=GF CC   important for correct morphogenesis [1]. The family also
#=GF CC   contains higher eukaryote Tpm3 members.
#=GF SQ   1272
#=GS A0A367JY92_RHIAZ/45-111     AC A0A367JY92.1
#=GS A0A074XN30_9PEZI/7-149      AC A0A074XN30.1
#=GS S4R2U0_MOUSE/7-152          AC S4R2U0.1
#=GS A0A1Y1UWM3_9FUNG/2-144      AC A0A1Y1UWM3.1
#=GS A0A0B1PDK2_UNCNE/7-149      AC A0A0B1PDK2.1
#=GS A0A484B9Z8_DRONA/7-83       AC A0A484B9Z8.1
#=GS Q5KF76_CRYNJ/8-149          AC Q5KF76.1
#=GS A0A068RYZ0_9FUNG/45-111     AC A0A068RYZ0.1
#=GS A0A182XV84_ANOST/7-85       AC A0A182XV84.1
#=GS A0A1S7HMX3_9SACH/7-149      AC A0A1S7HMX3.1
#=GS A0A427XNP3_9TREE/7-149      AC A0A427XNP3.1
#=GS A0A0D2A9T4_9EURO/7-157      AC A0A0D2A9T4.1
#=GS A0A162JAU3_CORFA/7-149      AC A0A162JAU3.1
#=GS A0A367IP43_RHIST/7-122      AC A0A367IP43.1
#=GS A0A3N4IYY8_9PEZI/7-150      AC A0A3N4IYY8.1
#=GS A0A6Q2Z250_ESOLU/7-94       AC A0A6Q2Z250.1
#=GS A0A0D1YRV2_9PEZI/7-149      AC A0A0D1YRV2.1
#=GS A0A3M7ASA7_HORWE/7-149      AC A0A3M7ASA7.1
#=GS A0A166HWU1_9AGAM/7-149      AC A0A166HWU1.1
#=GS A0A1C7MB52_GRIFR/7-149      AC A0A1C7MB52.1
#=GS A0A151PIW8_ALLMI/7-90       AC A0A151PIW8.1
#=GS M2LBP0_BAUPA/7-149          AC M2LBP0.1
#=GS A0A1G4J5U5_9SACH/7-149      AC A0A1G4J5U5.1
#=GS A0A319D874_9EURO/7-149      AC A0A319D874.1
#=GS A0A397IJD1_9GLOM/7-62       AC A0A397IJD1.1
#=GS A0A423SL41_PENVA/7-126      AC A0A423SL41.1
#=GS A0A2B7Z414_9EURO/1-142      AC A0A2B7Z414.1
#=GS A0A1Y2CM18_9FUNG/2-144      AC A0A1Y2CM18.1
#=GS A0A167BXY1_9ASCO/1-141      AC A0A167BXY1.1
#=GS A0A436ZQC5_9PEZI/39-181     AC A0A436ZQC5.1
#=GS L5LKC3_MYODS/7-85           AC L5LKC3.1
#=GS A0A0N4V4S0_ENTVE/1-79       AC A0A0N4V4S0.1
#=GS S2J3Q2_MUCC1/44-111         AC S2J3Q2.1
#=GS A2AIM5_MOUSE/7-105          AC A2AIM5.8
#=GS A0A5C6NIS2_9TELE/7-88       AC A0A5C6NIS2.1
#=GS A0A1B8FAV5_9PEZI/7-149      AC A0A1B8FAV5.1
#=GS A0A5M9K212_MONFR/1-142      AC A0A5M9K212.1
#=GS A0A1R1Y9Z3_9FUNG/7-147      AC A0A1R1Y9Z3.1
#=GS A0A5Q4C3G0_9PEZI/7-149      AC A0A5Q4C3G0.1
#=GS A0A179G4G7_METCM/56-115     AC A0A179G4G7.1
#=GS C6HBH0_AJECH/7-149          AC C6HBH0.1
#=GS A0A4T0W388_9PEZI/7-149      AC A0A4T0W388.1
#=GS H9GGI7_ANOCA/7-80           AC H9GGI7.1
#=GS A0A671EYW4_RHIFE/7-88       AC A0A671EYW4.1
#=GS A0A1A5ZU22_9TREE/14-115     AC A0A1A5ZU22.1
#=GS A0A367KNJ5_RHIST/618-684    AC A0A367KNJ5.1
#=GS A0A3G2S242_9BASI/7-149      AC A0A3G2S242.1
#=GS A0A372QW75_9GLOM/1-143      AC A0A372QW75.1
#=GS A0A0C9MF20_9FUNG/7-61       AC A0A0C9MF20.1
#=GS A0A0C9Y4T9_9AGAR/8-150      AC A0A0C9Y4T9.1
#=GS A0A1E3PBR7_WICAA/7-149      AC A0A1E3PBR7.1
#=GS A0A0C2XIW1_AMAMU/8-150      AC A0A0C2XIW1.1
#=GS A0A2I2GN17_9EURO/1-142      AC A0A2I2GN17.1
#=GS A0A1V9XFA7_9ACAR/133-207    AC A0A1V9XFA7.1
#=GS A0A372R079_9GLOM/57-126     AC A0A372R079.1
#=GS A0A2I0T393_LIMLA/7-83       AC A0A2I0T393.1
#=GS A0A4V5N9Z1_9PEZI/1-142      AC A0A4V5N9Z1.1
#=GS A0A2G9V400_TELCI/7-109      AC A0A2G9V400.1
#=GS A0A3M0IZ00_HIRRU/7-78       AC A0A3M0IZ00.1
#=GS B6Q8K6_TALMQ/7-149          AC B6Q8K6.1
#=GS A0A6H5IX78_9HYME/189-270    AC A0A6H5IX78.1
#=GS A0A317SNH4_9PEZI/7-150      AC A0A317SNH4.1
#=GS A0A165MHK9_EXIGL/29-97      AC A0A165MHK9.1
#=GS B4GLB9_DROPE/7-100          AC B4GLB9.1
#=GS A0A5C3ELL1_9BASI/84-226     AC A0A5C3ELL1.1
#=GS A0A081CIS3_PSEA2/7-138      AC A0A081CIS3.1
#=GS A0A4V3SHL8_9PEZI/7-151      AC A0A4V3SHL8.1
#=GS A0A4W4G4S0_ELEEL/7-81       AC A0A4W4G4S0.1
#=GS A0A150VG52_9PEZI/7-149      AC A0A150VG52.1
#=GS A0A094JGE8_9PEZI/7-149      AC A0A094JGE8.1
#=GS A0A0L6W6U6_9AGAR/82-185     AC A0A0L6W6U6.1
#=GS W9YUA0_9EURO/11-161         AC W9YUA0.1
#=GS A0A1V6S0C1_9EURO/7-149      AC A0A1V6S0C1.1
#=GS A0A507FUH7_9FUNG/962-1104   AC A0A507FUH7.1
#=GS A0A1V8UPL5_9PEZI/7-149      AC A0A1V8UPL5.1
#=GS A0A0K8LE88_9EURO/1-142      AC A0A0K8LE88.1
#=GS K1QFV5_CRAGI/7-91           AC K1QFV5.1
#=GS A0A1Y1XFJ4_9FUNG/76-187     AC A0A1Y1XFJ4.1
#=GS A0A261XXE7_9FUNG/45-111     AC A0A261XXE7.1
#=GS A0A0L1J0F6_ASPNO/1-68       AC A0A0L1J0F6.1
#=GS A0A423VPF7_9PEZI/10-152     AC A0A423VPF7.1
#=GS A0A2G8RU33_9APHY/7-149      AC A0A2G8RU33.1
#=GS S3CX36_OPHP1/7-149          AC S3CX36.1
#=GS C1HDY0_PARBA/1-142          AC C1HDY0.2
#=GS A0A3L8RVB4_CHLGU/7-82       AC A0A3L8RVB4.1
#=GS A0A1E5RNK9_9ASCO/7-149      AC A0A1E5RNK9.1
#=GS A0A423XGW0_9PEZI/10-152     AC A0A423XGW0.1
#=GS A0A367IY35_RHIAZ/45-111     AC A0A367IY35.1
#=GS A0A2G4SZ81_RHIZD/45-111     AC A0A2G4SZ81.1
#=GS A0A1B7TBT8_9ASCO/7-149      AC A0A1B7TBT8.1
#=GS I1C950_RHIO9/7-74           AC I1C950.1
#=GS A0A0L0NII5_TOLOC/25-129     AC A0A0L0NII5.1
#=GS A0A177DN76_ALTAL/7-149      AC A0A177DN76.1
#=GS W4K1A3_HETIT/7-149          AC W4K1A3.1
#=GS A0A2C5YSU5_9HYPO/7-149      AC A0A2C5YSU5.1
#=GS A0A0D2CAT3_9EURO/7-157      AC A0A0D2CAT3.1
#=GS A0A2T2N583_CORCC/7-149      AC A0A2T2N583.1
#=GS A5E0H9_LODEL/7-149          AC A5E0H9.1
#=GS A0A0C7N2C1_9SACH/7-149      AC A0A0C7N2C1.1
#=GS A0A1L9NE82_ASPTC/7-149      AC A0A1L9NE82.1
#=GS A0A164VUT2_9AGAM/7-149      AC A0A164VUT2.1
#=GS A0A182GDW2_AEDAL/7-86       AC A0A182GDW2.1
#=GS A0A674DB23_SALTR/17-81      AC A0A674DB23.1
#=GS A0A4V5NEB5_9PEZI/1-142      AC A0A4V5NEB5.1
#=GS A0A151PJ09_ALLMI/7-90       AC A0A151PJ09.1
#=GS A0A1Y2X4L4_9PEZI/8-160      AC A0A1Y2X4L4.1
#=GS A0A0D7BPP3_9AGAR/39-112     AC A0A0D7BPP3.1
#=GS A0A367KU09_RHIST/45-111     AC A0A367KU09.1
#=GS A0A163MRE7_ABSGL/45-111     AC A0A163MRE7.1
#=GS A0A229X3P8_9EURO/1-142      AC A0A229X3P8.1
#=GS A0A1Y1XJU9_9FUNG/7-149      AC A0A1Y1XJU9.1
#=GS E9DGN1_COCPS/11-153         AC E9DGN1.1
#=GS A0A409XL41_PSICY/8-150      AC A0A409XL41.1
#=GS A0A094FC69_9PEZI/7-149      AC A0A094FC69.1
#=GS A0A183LIU4_9TREM/41-113     AC A0A183LIU4.1
#=GS TPM2_YEAST/7-149            AC P40414.1
#=GS A0A090L9S7_STRRB/7-91       AC A0A090L9S7.1
#=GS A0A1S7HBK4_9SACH/7-149      AC A0A1S7HBK4.1
#=GS A0A2X0LV29_9BASI/7-126      AC A0A2X0LV29.1
#=GS A0A1X6N6H8_9APHY/7-149      AC A0A1X6N6H8.1
#=GS A0A1X0SD50_RHIZD/7-149      AC A0A1X0SD50.1
#=GS A0A0R3WVE5_HYDTA/20-100     AC A0A0R3WVE5.1
#=GS A0A1X2IZF2_9FUNG/45-111     AC A0A1X2IZF2.1
#=GS A0A4R8RTT4_COLTR/7-149      AC A0A4R8RTT4.1
#=GS A0A068RW89_9FUNG/45-111     AC A0A068RW89.1
#=GS A0A2R6Q6Q4_ACTCC/313-433    AC A0A2R6Q6Q4.1
#=GS A0A1V8T7T0_9PEZI/7-149      AC A0A1V8T7T0.1
#=GS W9CJ83_SCLBF/7-149          AC W9CJ83.1
#=GS I1BYI9_RHIO9/7-149          AC I1BYI9.1
#=GS A0A2C5X5E2_9PEZI/7-149      AC A0A2C5X5E2.1
#=GS A0A0W0FXM8_9AGAR/8-150      AC A0A0W0FXM8.1
#=GS A0A2S4KUU8_9HYPO/7-162      AC A0A2S4KUU8.1
#=GS A0A4Z1JP78_9HELO/7-149      AC A0A4Z1JP78.1
#=GS A0A1A6H1Z0_NEOLE/7-120      AC A0A1A6H1Z0.1
#=GS A0A0B7NQD0_9FUNG/7-73       AC A0A0B7NQD0.1
#=GS A0A5N6DJX7_ASPPA/7-74       AC A0A5N6DJX7.1
#=GS Q0VBX6_BOVIN/7-82           AC Q0VBX6.1
#=GS A0A1E3HE31_9TREE/14-155     AC A0A1E3HE31.1
#=GS A0A095D3X2_CRYGR/8-149      AC A0A095D3X2.1
#=GS A0A1E3Q1S6_LIPST/1-143      AC A0A1E3Q1S6.1
#=GS A0A367IY35_RHIAZ/7-70       AC A0A367IY35.1
#=GS A0A1R3RGV4_ASPC5/7-149      AC A0A1R3RGV4.1
#=GS I1CQW7_RHIO9/45-111         AC I1CQW7.1
#=GS A0A5J5DAK0_9PERO/7-134      AC A0A5J5DAK0.1
#=GS A0A068RQ27_9FUNG/7-149      AC A0A068RQ27.1
#=GS A0A5N7A116_9EURO/48-111     AC A0A5N7A116.1
#=GS U4U063_DENPD/6-95           AC U4U063.1
#=GS A0A433PUE5_9FUNG/464-606    AC A0A433PUE5.1
#=GS A0A674M9R8_TAKRU/7-73       AC A0A674M9R8.1
#=GS A0A015L1X9_RHIIW/43-112     AC A0A015L1X9.1
#=GS C0NWT6_AJECG/7-149          AC C0NWT6.1
#=GS A0A066VFD1_TILAU/16-158     AC A0A066VFD1.1
#=GS B8LZD5_TALSN/1-142          AC B8LZD5.1
#=GS A0A183AHT6_9TREM/10-84      AC A0A183AHT6.1
#=GS A0A0F7ZUV7_9HYPO/7-149      AC A0A0F7ZUV7.1
#=GS A0A1J9PPF3_9EURO/1-142      AC A0A1J9PPF3.1
#=GS A0A1I7V9I5_LOALO/7-81       AC A0A1I7V9I5.1
#=GS A0A151I2U1_9HYME/7-89       AC A0A151I2U1.1
#=GS W5NBY5_LEPOC/7-73           AC W5NBY5.1
#=GS A0A317V978_9EURO/7-149      AC A0A317V978.1
#=GS A0A556UG84_BAGYA/7-89       AC A0A556UG84.1
#=GS A0A0L0HSL9_SPIPD/45-111     AC A0A0L0HSL9.1
#=GS A0A397I3D5_9EURO/1-142      AC A0A397I3D5.1
#=GS A0A5N6U1P7_9EURO/7-149      AC A0A5N6U1P7.1
#=GS B8MW01_ASPFN/7-149          AC B8MW01.1
#=GS A0A0R3WVV2_HYDTA/7-98       AC A0A0R3WVV2.1
#=GS A0A3M0IZ00_HIRRU/57-145     AC A0A3M0IZ00.1
#=GS A0A369H4H3_9HYPO/7-149      AC A0A369H4H3.1
#=GS A0A670KNL7_PODMU/7-84       AC A0A670KNL7.1
#=GS A0A507DD01_9FUNG/7-149      AC A0A507DD01.1
#=GS A0A5E4BTY1_MARMO/7-85       AC A0A5E4BTY1.1
#=GS A0A0F9ZKS0_TRIHA/7-157      AC A0A0F9ZKS0.1
#=GS A0A0B7NHJ5_9FUNG/60-187     AC A0A0B7NHJ5.1
#=GS A0A183SUW7_SCHSO/7-94       AC A0A183SUW7.1
#=GS A0A5C6P9T4_9TELE/7-85       AC A0A5C6P9T4.1
#=GS A0A132B6R1_9HELO/7-149      AC A0A132B6R1.1
#=GS A0A0D1VR01_9EURO/7-157      AC A0A0D1VR01.1
#=GS K5WM47_PHACS/7-67           AC K5WM47.1
#=GS A0A319F4L2_ASPSB/7-149      AC A0A319F4L2.1
#=GS S2JCU8_MUCC1/49-111         AC S2JCU8.1
#=GS A0A1Y1XFJ4_9FUNG/7-104      AC A0A1Y1XFJ4.1
#=GS A0A0F8B1E0_CERFI/7-149      AC A0A0F8B1E0.1
#=GS A0A443I3K4_BYSSP/7-149      AC A0A443I3K4.1
#=GS A0A3N0YHU1_ANAGA/7-90       AC A0A3N0YHU1.1
#=GS A0A4Q4V6R0_9PEZI/7-149      AC A0A4Q4V6R0.1
#=GS A0A016STZ4_9BILA/7-81       AC A0A016STZ4.1
#=GS A0A4S4LKA2_9AGAM/47-104     AC A0A4S4LKA2.1
#=GS A0A026WJ77_OOCBI/7-110      AC A0A026WJ77.1
#=GS V5FQ13_BYSSN/7-149          AC V5FQ13.1
#=GS B0CUA0_LACBS/10-152         AC B0CUA0.1
#=GS A0A1X0SAT2_RHIZD/44-111     AC A0A1X0SAT2.1
#=GS S8BJ98_DACHA/7-149          AC S8BJ98.1
#=GS A0A2I3MYM9_PAPAN/7-152      AC A0A2I3MYM9.1
#=GS A0A517LB11_9PEZI/7-149      AC A0A517LB11.1
#=GS A0A0L6URM5_9BASI/13-152     AC A0A0L6URM5.1
#=GS A0A4Q4WXA2_9PEZI/7-149      AC A0A4Q4WXA2.1
#=GS F4P372_BATDJ/7-149          AC F4P372.1
#=GS F4X196_ACREC/7-86           AC F4X196.1
#=GS A0A1Y2IPM5_PYCCO/7-149      AC A0A1Y2IPM5.1
#=GS A0A5S6PE19_BRUMA/7-82       AC A0A5S6PE19.1
#=GS L8X3F8_THACA/85-222         AC L8X3F8.1
#=GS A0A158R239_NIPBR/7-87       AC A0A158R239.1
#=GS A0A084QF76_STAC4/7-149      AC A0A084QF76.1
#=GS V8N1C7_OPHHA/7-80           AC V8N1C7.1
#=GS A0A2P8YRT6_BLAGE/7-88       AC A0A2P8YRT6.1
#=GS A0A067LUA8_9AGAM/10-65      AC A0A067LUA8.1
#=GS S8FS20_FOMPI/7-149          AC S8FS20.1
#=GS A0A5N6SRP1_ASPPS/49-111     AC A0A5N6SRP1.1
#=GS A0A4C1SXB8_EUMVA/39-123     AC A0A4C1SXB8.1
#=GS A0A0C9MUU4_9FUNG/7-149      AC A0A0C9MUU4.1
#=GS A0A1C7NNC5_9FUNG/45-111     AC A0A1C7NNC5.1
#=GS K9GU53_PEND2/7-149          AC K9GU53.1
#=GS A0A167XD28_9HYPO/1-151      AC A0A167XD28.1
#=GS A0A4Q4UQQ7_9PEZI/7-149      AC A0A4Q4UQQ7.1
#=GS A0A1V6Z3B8_PENNA/7-149      AC A0A1V6Z3B8.1
#=GS A0A1S9DWZ8_ASPOZ/1-142      AC A0A1S9DWZ8.1
#=GS M7UB20_BOTF1/7-149          AC M7UB20.1
#=GS H3FQ19_PRIPA/31-152         AC H3FQ19.2
#=GS A0A195DP88_9HYME/7-85       AC A0A195DP88.1
#=GS A0A165K0H0_XYLHT/10-152     AC A0A165K0H0.1
#=GS A0A507E8E7_9FUNG/7-149      AC A0A507E8E7.1
#=GS A0A165WE78_9AGAM/7-149      AC A0A165WE78.1
#=GS A0A060YU53_ONCMY/7-84       AC A0A060YU53.1
#=GS A0A6A4XA68_AMPAM/7-121      AC A0A6A4XA68.1
#=GS A0A0L0NII5_TOLOC/140-189    AC A0A0L0NII5.1
#=GS A0A1Y1YPT2_9PLEO/7-149      AC A0A1Y1YPT2.1
#=GS A0A178EC90_9PLEO/7-149      AC A0A178EC90.1
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TPM1_YEAST/7-71                        .............................KLSNLKLEAESWQE.KYEEL.KEKNK....DLEQENV..E.............K.............E.....N.....QIKS.L.TVKN.QQLEDE.IE....K.L....E.AG....LS..DSK.QT-..--.-....-.-.....-..-..-....---.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------e.................................................
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A5WW36_DANRE/7-81                      .............................KMMMLKLDKENALD.QAEQA.ETDRK....AAEERSK..Q.............H.............E.....D.....ELIQ.M.QKKL.KGTEDE.LD....K.Y....S.EA....LK..DAQ.EKL..EI.S....E.K.....K..A..A....---.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------dv................................................
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K2RPC7_MACPH/7-149                     .............................RMNALRIEADEATA.KVEEL.SADKK....RLEQENL..A.............K.............E.....Q.....EITS.L.THKN.QLLESE.VE....K.L....E.QS....LK..DAK.AIA..DE.S....T.Q.....A..G..T....HNE.....................SLT.R..RVQ..LLE....EEA..EEAD...K.NL..RET.......NEK.............LRQTDV...R.AGHYER..K............VQ.ALE.....AER....DQ..WESK..Y..E.EMAKKYADTKK..................................................
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K5VT12_PHACS/7-149                     .............................RLASLRQEADNAIA.RAEGA.EAKVK....QLDQQLL..E.............K.............E.....Q.....EVKS.L.RVKL.DLADAN.LE....K.S....E.SK....LT..ETK.AAA..LD.A....E.S.....S..K..T....TID.....................ALQ.R..KVQ..LLE....EEL..DAAE...K.HS..KEV.......VEK.............LRQVDV...K.AEEFER..R............CH.SLD.....QER....EQ..WEKK..Y..E.ETQEKLRKSQ-a.................................................
B4UN77_KLULA/7-149                     .............................KLSNLKLEAESWQD.KYEEL.KEQVK....VLEQEKT..D.............N.............E.....N.....LIKS.L.TTKN.QTLEEE.VE....T.L....E.GQ....VS..EHK.QLA..ED.S....T.N.....L..K..S....HNE.....................NFS.K..KNQ..QLE....EEL..EEND...S.KL..KET.......TEK.............LREADL...K.VEQLER..K............VT.SLE.....QER....DD..LEKK..Y..D.DLQTKYDAAK-a.................................................
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W2RRV1_9EURO/12-161                    .............................KMNSLRIEADENAA.KAEES.KKRVK....ELEQDNL..Q.............K.............E.....Q.....EITS.L.NHRN.QLLEAE.VE....K.L....E.TG....IK..EAK.AAA..SD.A....S.Q.....H..G..Q....QNE.....................ALT.R..RLQ..LLE....EEA..ESAD...K.TL..RET.......NEK.............LRQTDV...K.AGHYER..K............VQ.AAE.....QAR....DE..WEAK..Y..E.EMAKKHADLQ-kelqeleq..........................................
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TPM_SCHPO/7-149                        .............................KINAARAETDEAVA.RAEAA.EAKLK....EVELQLS..L.............K.............E.....Q.....EYES.L.SRKS.EAAESQ.LE....E.L....E.EE....TK..QLR.LKA..DN.E....D.I.....Q..K..T....EAE.....................QLS.R..KVE..LLE....EEL..ETND...K.LL..RET.......TEK.............MRQTDV...K.AEHFER..R............VQ.SLE.....RER....DD..MEQK..L..E.EMTDKYTKVK-a.................................................
H3C901_TETNG/4-119                     .............................KMQMLKLDKENALD.RAEQA.ETDKK....AAEDRSK..Q.............L.............E.....D.....ELRE.L.EKKL.RVTEDE.RD....R.V....I.EE....FQ..TAE.EKL..LT.A....E.E.....V..A..T....KLEdd.................lvALQ.K..KLK..GTE....DEL..DKFS...E.AL..KDA.......QEK.............LELAEK...K.A-----..-............--.---.....---....--..----..-..-.-----------td................................................
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B2VZI7_PYRTR/7-149                     .............................RMEALRVEADESSA.RAEEL.KAKVK....QLESETT..Q.............K.............E.....Q.....EITS.L.SHKN.QVLESE.VE....K.L....E.TQ....VK..TYK.DEA..GA.G....A.Q.....A..G..T....QAE.....................SLQ.R..KIQ..VLE....EEA..EESD...R.TI..REL.......NEK.............LRQTDV...K.SGHYER..K............VQ.ALE.....QSR....DQ..WETK..Y..E.EMAKKYADTKK..................................................
U9TSJ3_RHIID/7-149                     .............................KINSLRAEADASVQ.RAENA.EAELK....KAKEDII..V.............K.............E.....Q.....EIIS.L.TNKI.SLLEAE.VE....R.A....D.KK....IS..DLK.SAK..EE.E....E.S.....T..S..S....TTE.....................ALQ.R..KIS..ILE....NEL..DTTE...K.NL..KET.......TEK.............LRTTDV...K.AEHFER..K............CN.TLE.....SEK....AD..LEKK..L..D.EKEQEFKK---kee...............................................
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D4B1V8_ARTBC/50-192                    .............................KIENMRQEIDDGLS.KIEEQ.KARIK....ELEQENL..S.............K.............E.....Q.....EVTS.L.THRN.QLLEQR.VE....T.L....E.VT....LK..EAK.TKA..SE.A....A.Q.....D..S..S....QNE.....................ALQ.R..RIQ..LME....EEA..EQTD...K.TL..RET.......NEK.............LRQTDV...K.AGHFER..K............VQ.ALE.....ATR....EQ..WETK..Y..E.EMSKQYAAVK-e.................................................
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G2XQ92_BOTF4/7-149                     .............................KMNTLRIEADEATA.KVQEL.QEKVK....ALEQENL..Q.............K.............E.....Q.....EITS.L.THKN.NLLETE.VE....K.L....E.GG....IK..EAK.AVA..EE.G....S.Q.....H..G..T....QNE.....................TLQ.R..RLQ..LLE....EEA..EEAD...K.NL..RET.......NDK.............LRQTDV...K.AGHFER..K............VQ.ALE.....QDR....DQ..WEAK..F..E.EMAKKYATVQK..................................................
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S2JCU8_MUCC1/7-73                      .............................KLASLRAEAEQANA.LAEEY.EAKIK....QLELEHT..S.............K.............D.....H.....ELLS.I.QIRA.KNLEEQ.LD....K.T....E.AK....LH..TVS.A--..--.-....-.-.....-..-..-....---.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------dynk..............................................
A0A2G7G5G6_9EURO/1-67                  .............................-MKSLQTEADTAQT.EVEKL.TAKIQ....ELEQDNQ..S.............K.............D.....E.....EIAT.L.STRH.QALEEQ.VE....E.T....E.KL....VR..EVK.RLF..NE.-....-.-.....-..-..-....---.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------d.................................................
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S7PKF3_MYOBR/7-89                      .............................KMQMLKLDKENALD.RAEQA.EAEQK....QAEERSK..Q.............L.............E.....D.....ELAA.M.QKKL.KGTEDE.LD....K.Y....S.EA....LK..DAQ.EKL..EL.A....E.K.....K..A..A....D--.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------efhdlfqdl.........................................
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I1CI19_RHIO9/493-560                   .............................RLSLLRAEAEAANT.QADEY.EAKIK....QLEQEHT..A.............K.............D.....H.....EILS.L.QIRT.KNLEER.LD....K.T....E.TQ....LQ..TTS.SNS..ND.-....-.-.....-..-..-....---.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------a.................................................
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J4GL39_9APHY/139-187                   .........................lanr--------------.-----.-----....-------..-.............-.............-.....-.....----.-.----.------.--....-.-....-.--....--..---.---..--.-....-.-.....-..-..-....---.....................---.-..---..---....---..----...-.--..--V.......MHR.............LRQVDV...K.AEHFER..Q............VQ.RLE.....QER....DQ..WEKK..Y..E.EAQTKYRESK-a.................................................
A0A0B2WHC4_METAS/1-151                 .............................-MSSLRLEADEAAA.KVQEL.QQKVK....GLEEQNT..A.............K.............E.....Q.....ENRS.L.QHRN.DLLEAE.VE....K.L....E.AA....MK..DFK.KAA..DE.G....Q.Q.....H..G..T....QNE.....................TLQ.R..RLQ..LLE....EEA..EDAD...K.TL..REA.......NEK.............LRQTDV...K.AGHFER..K............VQ.ALE.....QER....DQ..WEQK..Y..E.EMSKKHSTLQ-keleelqnei........................................
J8LIP8_SACAR/7-71                      .............................KLSTLKLEAESWQE.KYEEL.KEKNK....DLEQDTV..E.............K.............E.....N.....QVKS.L.TVKN.QQLEEE.IE....K.L....E.SG....LS..GSK.QT-..--.-....-.-.....-..-..-....---.....................---.-..---..---....---..----...-.--..---.......---.............------...-.------..-............--.---.....---....--..----..-..-.-----------e.................................................
A0A4Q7JQ97_METCM/1-151                 .............................-MNSLRLEADEAAA.KVEEL.QAKVK....TLEQENL..S.............K.............E.....Q.....EITS.L.QHKN.NLLEGE.VE....K.L....E.SA....TK..DFK.KAA..DE.G....Q.Q.....H..G..T....QNE.....................TLQ.R..RLQ..LLE....EEA..EDAD...K.TL..REA.......NEK.............LRQTDV...K.AGHFER..K............VQ.ALE.....QER....DQ..WEQK..Y..E.EMAKKHSTLQ-keleelqnei........................................
A0A0S7DTF1_9EURO/1-142                 .............................-MNALRLEADEAQN.KVEEL.KAKVK....TLEQENL..A.............K.............E.....Q.....EITS.L.NHRN.QLLEGE.VE....K.L....E.AA....LK..EAK.ESA..NQ.S....A.Q.....H..D..T....QNE.....................ALQ.R..RVQ..LLE....EEA..EEAD...R.NL..RET.......NEK.............LRQTDV...K.AGHYER..K............VQ.ALE.....ASR....DQ..WESK..Y..E.EMAKKYAELQK..................................................
A0A1X0SE57_RHIZD/518-584               .............................--------------.-----.-----....-------..-.............-.............-.....-.....----.-.----.------.--....-.-....-.--....--..---.---..--.-....-.-.....-..-..-....---.....................SLQ.I..RIK..NLE....EQL..DKTE...N.SL..QTT.......STD.............YNKADL...R.AEEAER..K............VQ.KLE.....QEL....LD..KEQG..Y..E.ELTEKYNSAK-n.................................................
A0A5N5P8Q7_9PEZI/7-149                 .............................KMNKLRLEADESSA.KAEEY.QAKVK....VLEQENL..A.............K.............E.....Q.....EITS.L.QHKN.GLLEAE.VE....K.L....E.KQ....VA..DLK.KAA..DD.G....Q.Q.....H..G..T....QNE.....................TLT.R..RLQ..LLE....EEA..EEAD...K.TL..REA.......NEK.............LRQTDV...K.AGHFER..K............VQ.ALE.....TER....DT..WEAK..Y..E.EMAKKYADVQK..................................................
#=GC seq_cons                          .............................KhptL+lEs-pAhs.+sEph.cschK....phEpcsh..p.............+.............E.....p.....ElsS.L.p+K..phLEs-.l-....K.h....-.pp....lp..-h+.pth..pp.u....p.p.....p..t..s....ps-.....................sLp.+..+lp..hLE....--h..-ps-...c.pl..+-s.......scK.............L+psDl...+.AtphER..p............lt.tlE.....tpt....tp..hEt+..h..-.-h.tchtt.p...................................................
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