GenomeNet

Database: Pfam
Entry: Tubulin_3
LinkDB: Tubulin_3
Original site: Tubulin_3 
#=GF ID   Tubulin_3
#=GF AC   PF14881.7
#=GF DE   Tubulin domain
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9P6K5
#=GF GA   30.00 30.00;
#=GF TC   30.10 30.30;
#=GF NC   29.60 29.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12702300
#=GF RT   Preliminary characterisation of DML1, an essential Saccharomyces
#=GF RT   cerevisiae gene  related to misato of Drosophila melanogaster.
#=GF RA   Gurvitz A, Hartig A, Ruis H, Hamilton B, de Couet HG;
#=GF RL   FEMS Yeast Res. 2002;2:123-135.
#=GF RN   [2]
#=GF RM   17349998
#=GF RT   Human Misato regulates mitochondrial distribution and
#=GF RT   morphology.
#=GF RA   Kimura M, Okano Y;
#=GF RL   Exp Cell Res. 2007;313:1393-1404.
#=GF DR   INTERPRO; IPR029209;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This family includes the tubulin alpha, beta and gamma chains,
#=GF CC   as well as the bacterial FtsZ family of proteins. Misato from
#=GF CC   Drosophila and Dml1p from fungi are descendants of an ancestral
#=GF CC   tubulin-like protein, and exhibit regions with similarity to
#=GF CC   members of a GTPase family that includes eukaryotic tubulin and
#=GF CC   prokaryotic FtsZ. Dml1p and Misato have been co-opted into a
#=GF CC   role in mtDNA inheritance in yeast, and into a cell
#=GF CC   division-related mechanism in flies, respectively. Dml1p might
#=GF CC   additionally function in the partitioning of the mitochondrial
#=GF CC   organelle itself, or in the segregation of chromosomes, thereby
#=GF CC   explaining its essential requirement. This domain subject to
#=GF CC   extensive post-translational modifications.
#=GF SQ   1193
#=GS A0A2G8KPR1_STIJA/153-343    AC A0A2G8KPR1.1
#=GS J9P0H7_CANLF/153-347        AC J9P0H7.1
#=GS DML1_CANAL/133-354          AC Q5A2W2.1
#=GS U5CWA2_AMBTC/130-316        AC U5CWA2.1
#=GS A0A0C3NNF9_PHLGI/169-303    AC A0A0C3NNF9.1
#=GS A0A453JUC8_AEGTS/164-351    AC A0A453JUC8.1
#=GS A0A3Q1FYF3_9TELE/163-352    AC A0A3Q1FYF3.1
#=GS A0A2V5ISV9_9EURO/119-303    AC A0A2V5ISV9.1
#=GS A0A0D2X559_CAPO3/194-382    AC A0A0D2X559.1
#=GS A0A1S3HA85_LINUN/164-356    AC A0A1S3HA85.1
#=GS I2GYJ2_TETBL/124-315        AC I2GYJ2.1
#=GS I1IH01_BRADI/149-335        AC I1IH01.1
#=GS M5G9A7_DACPD/133-322        AC M5G9A7.1
#=GS C5YQV4_SORBI/148-332        AC C5YQV4.1
#=GS A0A0E0GBG9_ORYNI/158-345    AC A0A0E0GBG9.1
#=GS I0YMJ6_COCSC/114-300        AC I0YMJ6.1
#=GS A0A366R402_9HYPO/114-299    AC A0A366R402.1
#=GS A0A3Q4BFQ5_MOLML/134-319    AC A0A3Q4BFQ5.1
#=GS A0A182FMH3_ANOAL/139-332    AC A0A182FMH3.1
#=GS DML1_ASHGO/120-307          AC Q756C7.1
#=GS H3A2P6_LATCH/158-349        AC H3A2P6.2
#=GS A0A0L0G6D2_9EUKA/4-178      AC A0A0L0G6D2.1
#=GS A0A1V6URN7_9EURO/118-302    AC A0A1V6URN7.1
#=GS A0A1V6PMN2_PENDC/118-302    AC A0A1V6PMN2.1
#=GS B8P6A1_POSPM/98-160         AC B8P6A1.1
#=GS F7VSA5_SORMK/98-287         AC F7VSA5.1
#=GS A0A0C4DRQ9_MAGP6/152-340    AC A0A0C4DRQ9.1
#=GS A0A0D3HW72_9ORYZ/143-330    AC A0A0D3HW72.1
#=GS M3Y1Q9_MUSPF/84-277         AC M3Y1Q9.1
#=GS E9CY65_COCPS/119-303        AC E9CY65.1
#=GS A0A3B3SQN8_9TELE/167-357    AC A0A3B3SQN8.1
#=GS S7RRJ8_GLOTA/143-332        AC S7RRJ8.1
#=GS A0A060SSM5_PYCCI/134-243    AC A0A060SSM5.1
#=GS A0A0L0HRU7_SPIPD/129-320    AC A0A0L0HRU7.1
#=GS A0A446BJB4_9PEZI/119-288    AC A0A446BJB4.1
#=GS R0L000_ANAPL/31-222         AC R0L000.1
#=GS A0A452IUK8_9SAUR/159-350    AC A0A452IUK8.1
#=GS A0A448YF54_BRENA/118-314    AC A0A448YF54.1
#=GS A0A0V1CG32_TRIBR/1330-1531  AC A0A0V1CG32.1
#=GS A0A453JU92_AEGTS/93-280     AC A0A453JU92.1
#=GS A0A0D3FG16_9ORYZ/125-312    AC A0A0D3FG16.1
#=GS U5HGP1_USTV1/79-230         AC U5HGP1.1
#=GS A0A369JAA7_HYPMA/130-319    AC A0A369JAA7.1
#=GS A0A3B0JQR1_DROGU/112-308    AC A0A3B0JQR1.1
#=GS A0A2K6QRM4_RHIRO/152-345    AC A0A2K6QRM4.1
#=GS A0A0E0CXS6_9ORYZ/143-330    AC A0A0E0CXS6.1
#=GS A0A2P6U0R0_CHLSO/163-355    AC A0A2P6U0R0.1
#=GS A0A250WZG1_9CHLO/197-334    AC A0A250WZG1.1
#=GS A0A2X0MEK0_9BASI/56-227     AC A0A2X0MEK0.1
#=GS M3BCP6_PSEFD/120-304        AC M3BCP6.1
#=GS A0A0P0YBU3_ORYSJ/143-308    AC A0A0P0YBU3.1
#=GS B3MRV4_DROAN/153-349        AC B3MRV4.1
#=GS A0A1U8INF3_GOSHI/150-337    AC A0A1U8INF3.1
#=GS A0A3Q0D7K3_MESAU/137-329    AC A0A3Q0D7K3.1
#=GS A0A167MJ93_9HYPO/1-142      AC A0A167MJ93.1
#=GS A0A1Y1Z2E7_9FUNG/124-208    AC A0A1Y1Z2E7.1
#=GS A0A1Y2X7R2_9PEZI/118-303    AC A0A1Y2X7R2.1
#=GS A0A165Q1M0_9AGAM/156-214    AC A0A165Q1M0.1
#=GS A0A2T9ZIX2_9FUNG/73-257     AC A0A2T9ZIX2.1
#=GS A0A409XK00_PSICY/72-274     AC A0A409XK00.1
#=GS L2FNR8_COLFN/141-326        AC L2FNR8.1
#=GS A0A3P8NJT0_ASTCA/160-349    AC A0A3P8NJT0.1
#=GS A0A1E3B6E6_9EURO/119-303    AC A0A1E3B6E6.1
#=GS H2AQG7_KAZAF/116-295        AC H2AQG7.1
#=GS A0A0L7RBC9_9HYME/127-316    AC A0A0L7RBC9.1
#=GS G8BB70_CANPC/146-338        AC G8BB70.1
#=GS A0A0V0RKS0_9BILA/1372-1555  AC A0A0V0RKS0.1
#=GS A0A365MX33_GIBIN/118-303    AC A0A365MX33.1
#=GS A0A2K6L113_RHIBE/102-295    AC A0A2K6L113.1
#=GS K0K870_WICCF/122-314        AC K0K870.1
#=GS A0A420H8R1_9PEZI/157-263    AC A0A420H8R1.1
#=GS E0CVU9_VITVI/151-338        AC E0CVU9.1
#=GS A0A154PIK9_DUFNO/127-314    AC A0A154PIK9.1
#=GS I1C6F1_RHIO9/6-172          AC I1C6F1.1
#=GS A0A2U9CXQ4_SCOMX/161-349    AC A0A2U9CXQ4.1
#=GS A0A2Y9ILF9_ENHLU/193-386    AC A0A2Y9ILF9.1
#=GS G1PEM6_MYOLU/153-346        AC G1PEM6.1
#=GS A0A1V6SM92_9EURO/104-288    AC A0A1V6SM92.1
#=GS A0A226MES3_CALSU/64-235     AC A0A226MES3.1
#=GS A0A232F208_9HYME/130-317    AC A0A232F208.1
#=GS A0A0D3DI28_BRAOL/473-649    AC A0A0D3DI28.1
#=GS A0A226NTY8_COLVI/66-259     AC A0A226NTY8.1
#=GS A0A2C5XUL2_9HYPO/125-303    AC A0A2C5XUL2.1
#=GS A0A0C3BLZ9_HEBCY/127-316    AC A0A0C3BLZ9.1
#=GS A0A0E0Q7Q7_ORYRU/1083-1270  AC A0A0E0Q7Q7.1
#=GS A0A2Y9EX67_PHYMC/153-346    AC A0A2Y9EX67.1
#=GS DML1_GIBZE/105-290          AC Q4IBL8.1
#=GS A5E051_LODEL/168-357        AC A5E051.1
#=GS A0A2G4SYL5_RHIZD/129-320    AC A0A2G4SYL5.1
#=GS G0RWU5_HYPJQ/120-307        AC G0RWU5.1
#=GS B8P6F2_POSPM/141-193        AC B8P6F2.1
#=GS A0A402EP29_9SAUR/154-342    AC A0A402EP29.1
#=GS A0A1S3AQ55_ERIEU/152-345    AC A0A1S3AQ55.1
#=GS M7Z0D4_TRIUA/137-324        AC M7Z0D4.1
#=GS A0A100I763_ASPNG/119-303    AC A0A100I763.1
#=GS A0A3Q0HA21_ALLSI/496-684    AC A0A3Q0HA21.1
#=GS A0A2J6JUR3_LACSA/145-332    AC A0A2J6JUR3.1
#=GS A0A2I0S9L5_9PEZI/120-304    AC A0A2I0S9L5.1
#=GS A0A2K5NI74_CERAT/153-346    AC A0A2K5NI74.1
#=GS C4QVG5_KOMPG/116-288        AC C4QVG5.1
#=GS A0A316ZI51_9BASI/153-363    AC A0A316ZI51.1
#=GS G9MX86_HYPVG/120-305        AC G9MX86.1
#=GS A0A2V0PMB1_9CHLO/155-352    AC A0A2V0PMB1.1
#=GS A0A1A0HI53_9ASCO/114-305    AC A0A1A0HI53.1
#=GS A0A1Y1XIY9_9FUNG/151-334    AC A0A1Y1XIY9.1
#=GS A0A179GRA7_PURLI/121-306    AC A0A179GRA7.1
#=GS E2RSB9_CANLF/153-347        AC E2RSB9.2
#=GS A0A1Y2E5R8_9FUNG/148-331    AC A0A1Y2E5R8.1
#=GS A0A401GXW1_9APHY/141-331    AC A0A401GXW1.1
#=GS A0A026W5I7_OOCBI/130-318    AC A0A026W5I7.1
#=GS A0A1V6NEA8_9EURO/119-303    AC A0A1V6NEA8.1
#=GS A0A1E4RN62_9ASCO/113-285    AC A0A1E4RN62.1
#=GS A0A3P8VK08_CYNSE/148-337    AC A0A3P8VK08.1
#=GS W4JMY6_9AGAM/131-321        AC W4JMY6.1
#=GS A0A150URN2_9PEZI/121-305    AC A0A150URN2.1
#=GS A0A1C7N061_9FUNG/128-319    AC A0A1C7N061.1
#=GS A0A010RLQ1_9PEZI/118-303    AC A0A010RLQ1.1
#=GS A0A3B3IUD2_HUMAN/153-346    AC A0A3B3IUD2.1
#=GS A0A195BQ53_9HYME/125-314    AC A0A195BQ53.1
#=GS A0A1J7J1V7_9PEZI/118-302    AC A0A1J7J1V7.1
#=GS A0A166AZX7_DAUCS/186-369    AC A0A166AZX7.1
#=GS A0A3Q1IWN8_ANATE/160-350    AC A0A3Q1IWN8.1
#=GS A0A2K6BL63_MACNE/118-311    AC A0A2K6BL63.1
#=GS A0A199VWT6_ANACO/182-367    AC A0A199VWT6.1
#=GS A0A0D1YSS9_9EURO/153-337    AC A0A0D1YSS9.1
#=GS A0A063BZA4_USTVR/120-305    AC A0A063BZA4.1
#=GS A0A2K5NIT5_CERAT/119-312    AC A0A2K5NIT5.1
#=GS A0A453JUK6_AEGTS/166-353    AC A0A453JUK6.1
#=GS A0A0D9Y0Z1_9ORYZ/110-296    AC A0A0D9Y0Z1.1
#=GS A0A395S3V1_FUSSP/118-303    AC A0A395S3V1.1
#=GS A0A137NUB9_CONC2/101-284    AC A0A137NUB9.1
#=GS A0A166CU36_9AGAM/123-311    AC A0A166CU36.1
#=GS DML1_CANGA/119-310          AC Q6FUF9.1
#=GS A0A3B3Z3U8_9TELE/160-347    AC A0A3B3Z3U8.1
#=GS J7RBL8_KAZNA/120-305        AC J7RBL8.1
#=GS A0A0S3T4U9_PHAAN/150-336    AC A0A0S3T4U9.1
#=GS W9YM09_9EURO/120-305        AC W9YM09.1
#=GS A0A3P8TW48_AMPPE/163-352    AC A0A3P8TW48.1
#=GS A0A1D2NE71_ORCCI/148-347    AC A0A1D2NE71.1
#=GS A0A0V0URE2_9BILA/1325-1526  AC A0A0V0URE2.1
#=GS A0A182Q3G6_9DIPT/80-274     AC A0A182Q3G6.1
#=GS A0A1L9X7P4_ASPAC/119-303    AC A0A1L9X7P4.1
#=GS A0A1Y3NP25_PIRSE/60-243     AC A0A1Y3NP25.1
#=GS A0A1Y2LXN6_EPING/121-308    AC A0A1Y2LXN6.1
#=GS A0A2G5I4R7_CERBT/120-304    AC A0A2G5I4R7.1
#=GS A0A1E3PBU2_WICAA/116-310    AC A0A1E3PBU2.1
#=GS K3Z4Z4_SETIT/148-332        AC K3Z4Z4.1
#=GS A0A420J5R5_9PEZI/205-378    AC A0A420J5R5.1
#=GS A0A0D7BB53_9AGAR/123-302    AC A0A0D7BB53.1
#=GS A0A2K5U3A8_MACFA/153-346    AC A0A2K5U3A8.1
#=GS A0A0B2X6F8_METAS/89-262     AC A0A0B2X6F8.1
#=GS A0A0L9UQN7_PHAAN/150-336    AC A0A0L9UQN7.1
#=GS A0A0V1N146_9BILA/85-268     AC A0A0V1N146.1
#=GS I3K832_ORENI/159-349        AC I3K832.1
#=GS A0A286U8A4_9AGAM/130-319    AC A0A286U8A4.1
#=GS M7P633_PNEMU/117-289        AC M7P633.1
#=GS A0A421J6I3_9ASCO/108-300    AC A0A421J6I3.1
#=GS A0A2K6L117_RHIBE/134-327    AC A0A2K6L117.1
#=GS A0A401L3L2_ASPAW/119-303    AC A0A401L3L2.1
#=GS G8BVH4_TETPH/118-308        AC G8BVH4.1
#=GS A0A2I4CJS5_9TELE/90-280     AC A0A2I4CJS5.1
#=GS A0A2J5I0Z8_9EURO/117-301    AC A0A2J5I0Z8.1
#=GS A0A1U8IQ03_GOSHI/150-337    AC A0A1U8IQ03.1
#=GS W5JM00_ANODA/139-332        AC W5JM00.1
#=GS A0A0D2PCV6_GOSRA/150-333    AC A0A0D2PCV6.1
#=GS C8VQ22_EMENI/119-303        AC C8VQ22.1
#=GS A0A1G4MD32_LACFM/136-329    AC A0A1G4MD32.1
#=GS A0A087X700_POEFO/166-355    AC A0A087X700.2
#=GS A0A1E4SIR5_9ASCO/115-309    AC A0A1E4SIR5.1
#=GS A0A1V8UGP9_9PEZI/119-302    AC A0A1V8UGP9.1
#=GS Q018N1_OSTTA/177-353        AC Q018N1.1
#=GS A0A2J7QQE2_9NEOP/127-318    AC A0A2J7QQE2.1
#=GS A0A1B8DID8_9PEZI/119-289    AC A0A1B8DID8.1
#=GS A0A2Y9M8V3_DELLE/153-346    AC A0A2Y9M8V3.1
#=GS A0A084QN43_STAC4/118-303    AC A0A084QN43.1
#=GS A0A109FBG8_9BASI/78-224     AC A0A109FBG8.1
#=GS A8Q4T4_MALGO/3-157          AC A8Q4T4.1
#=GS A0A2S7QVT1_9HELO/118-306    AC A0A2S7QVT1.1
#=GS A0A0J7K9U3_LASNI/93-281     AC A0A0J7K9U3.1
#=GS A0A1X6MKI0_9APHY/141-193    AC A0A1X6MKI0.1
#=GS S6EU88_ZYGB2/118-302        AC S6EU88.1
#=GS A0A3Q4H8V8_NEOBR/160-348    AC A0A3Q4H8V8.1
#=GS R7Q939_CHOCR/15-156         AC R7Q939.1
#=GS A0A0G4PQ53_PENCA/119-303    AC A0A0G4PQ53.1
#=GS A0A3Q3FS45_9LABR/146-336    AC A0A3Q3FS45.1
#=GS A0A2X0MN57_9BASI/80-213     AC A0A2X0MN57.1
#=GS A0A135UF48_9PEZI/118-303    AC A0A135UF48.1
#=GS A0A1V6RXS8_9EURO/118-302    AC A0A1V6RXS8.1
#=GS A0A024TIK2_9STRA/99-259     AC A0A024TIK2.1
#=GS W9ZCC0_9EURO/120-306        AC W9ZCC0.1
#=GS K7ISD8_NASVI/130-317        AC K7ISD8.1
#=GS A0A1Y1Z2E7_9FUNG/212-262    AC A0A1Y1Z2E7.1
#=GS A0A074W7H6_9PEZI/120-304    AC A0A074W7H6.1
#=GS A0A2K5DHQ9_AOTNA/156-344    AC A0A2K5DHQ9.1
#=GS A0A3B3VER6_9TELE/160-349    AC A0A3B3VER6.1
#=GS A0A0D2XZT4_FUSO4/1-149      AC A0A0D2XZT4.1
#=GS A0A1S3EF03_CICAR/98-282     AC A0A1S3EF03.1
#=GS A0A2Y9M356_DELLE/153-346    AC A0A2Y9M356.1
#=GS A0A2U3W4K6_ODORO/153-346    AC A0A2U3W4K6.1
#=GS M9MA84_PSEA3/174-395        AC M9MA84.1
#=GS A0A182M0L6_9DIPT/141-335    AC A0A182M0L6.1
#=GS A0A059AME4_EUCGR/144-330    AC A0A059AME4.1
#=GS A0A167GI06_9HYPO/120-305    AC A0A167GI06.1
#=GS A0A165HXA6_XYLHT/119-303    AC A0A165HXA6.1
#=GS A0A2K5UX38_MACFA/151-344    AC A0A2K5UX38.1
#=GS A0A0R3NY68_DROPS/151-347    AC A0A0R3NY68.1
#=GS A0A066XR16_COLSU/105-290    AC A0A066XR16.1
#=GS A0A0H2RY31_9AGAM/127-318    AC A0A0H2RY31.1
#=GS A0A167F7L7_9HYPO/120-305    AC A0A167F7L7.1
#=GS A0A3F2XZS6_DEKBR/117-271    AC A0A3F2XZS6.1
#=GS A0A2D0SD83_ICTPU/163-352    AC A0A2D0SD83.1
#=GS A0A0W4ZMD1_PNEJ7/116-288    AC A0A0W4ZMD1.1
#=GS A0A1S3M1E0_SALSA/159-348    AC A0A1S3M1E0.1
#=GS A0A317WXZ4_9EURO/119-303    AC A0A317WXZ4.1
#=GS F4Q9I8_CAVFA/113-305        AC F4Q9I8.1
#=GS A0A1B8AKI8_FUSPO/118-303    AC A0A1B8AKI8.1
#=GS E6ZQ10_SPORE/169-388        AC E6ZQ10.1
#=GS A0A178ZJG4_9EURO/119-303    AC A0A178ZJG4.1
#=GS MSTO1_DANRE/163-353         AC Q1L908.1
#=GS A0A1S3F3E4_DIPOR/156-346    AC A0A1S3F3E4.1
#=GS A0A074XCX1_AURPU/120-304    AC A0A074XCX1.1
#=GS A0A1V9XLW9_9ACAR/5-168      AC A0A1V9XLW9.1
#=GS A0A428TKH3_9HYPO/118-303    AC A0A428TKH3.1
#=GS A0A182LBW8_9DIPT/145-339    AC A0A182LBW8.1
#=GS B2AWJ1_PODAN/250-315        AC B2AWJ1.1
#=GS G3NCU5_GASAC/162-351        AC G3NCU5.1
#=GS A0A1E5RJN3_HANUV/176-330    AC A0A1E5RJN3.1
#=GS A0A197K2A2_9FUNG/137-329    AC A0A197K2A2.1
#=GS K7FG55_PELSI/127-318        AC K7FG55.1
#=GS A0A165XQE2_9AGAM/136-326    AC A0A165XQE2.1
#=GS A0A1Z5TNL6_HORWE/120-304    AC A0A1Z5TNL6.1
#=GS G0S6X1_CHATD/121-327        AC G0S6X1.1
#=GS A0A212F4P5_DANPL/123-321    AC A0A212F4P5.1
#=GS A0A2V5HY53_9EURO/119-303    AC A0A2V5HY53.1
#=GS A0A101MF40_9EURO/1-148      AC A0A101MF40.1
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J9P0H7_CANLF/153-347                   ....................................................kphvp----TEGSIKVWSDFL..SVHLHPRSIC...MI.........Q.........K..........Y....NH..............DGE.............AG.................R..............L.........EA......F...G..QG.ESI...L..K...E....P.......R................Y........L..E......E...L..E.D.......R...-.......LHFY.LEECDYLQ...GFQILCD.........LHN..........G..F.SGV...G...A...K.A.T.E.L.LQD.EY.......S.G..R.G....I.....I....T........W..G..L...LP................GP.YS.....L....G....E..P...Q....-.....-..........-.K............N.......I.Y..R.L.......L....NTAFGLVHM.SA........HSS.....LV.CPLSlgg........slglRpepp...........vtfphLR.........yDA..........................ALP....F....H.CG...A.ILATAL.DTLTVPYRL.............................................................
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